Matthew P. Bourbeau
Affiliations: | 2004 | University of Virginia, Charlottesville, VA |
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"Matthew P. Bourbeau"Mean distance: 8.62 | S | N | B | C | P |
Parents
Sign in to add mentor| James A. Marshall | grad student | 2004 | UVA | |
| (The total synthesis of (-)-callystatin A and related studies.) | ||||
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| Payton M, Belmontes B, Hanestad K, et al. (2023) Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers. Nature Cancer |
| Frohn M, Liu L, Siegmund AC, et al. (2020) The development of a structurally distinct series of BACE1 inhibitors via the (Z)-fluoro-olefin amide bioisosteric replacement. Bioorganic & Medicinal Chemistry Letters. 30: 127240 |
| Bourbeau MP, Ashton KS, Yan J, et al. (2014) Nonracemic synthesis of GK-GKRP disruptor AMG-3969. The Journal of Organic Chemistry. 79: 3684-7 |
| Kocienski P, Bourbeau MP, Ashton KS, et al. (2014) Synthesis of GK–GKRP Disruptor AMG-3969 Synfacts. 10: 671-671 |
| Bailis J, Fang L, Orf J, et al. (2013) Abstract 711: Small molecule compounds that target cell division cycle 7 (Cdc7) kinase inhibit cell proliferation and tumor growth. Cancer Research. 73: 711-711 |
| Zeng Q, Allen JG, Bourbeau MP, et al. (2010) Azole-based inhibitors of AKT/PKB for the treatment of cancer. Bioorganic & Medicinal Chemistry Letters. 20: 1559-64 |
| Zeng Q, Bourbeau MP, Wohlhieter GE, et al. (2010) 2-Aminothiadiazole inhibitors of AKT1 as potential cancer therapeutics. Bioorganic & Medicinal Chemistry Letters. 20: 1652-6 |
| Bourbeau MP, Rider JT. (2006) A convenient synthesis of 4-alkyl-5-aminoisoxazoles. Organic Letters. 8: 3679-80 |
| Marshall JA, Mikowski AM, Bourbeau MP, et al. (2006) Leptostatin: a synthetic hybrid of the cytotoxic polyketides callystatin A and leptomycin B. Bioorganic & Medicinal Chemistry Letters. 16: 320-3 |
| Marshall JA, Bourbeau MP. (2003) Synthesis of enantioenriched propargylic alcohols related to polyketide natural products. A comparison of methodologies. Organic Letters. 5: 3197-9 |