Tom Schrader
Affiliations: | 2002 | Boston College, Newton, MA, United States |
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| Ren A, Zhu X, Feichtinger K, et al. (2019) Discovery of a lead series of potent benzodiazepine 5-HT receptor agonists with high selectivity in functional and binding assays. Bioorganic & Medicinal Chemistry Letters. 126929 |
| Schrader TO, Zhu X, Kasem M, et al. (2018) Asymmetric syntheses of (R)-4-halo-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,n]naphthyridines, important 5-HT2C agonist precursors Tetrahedron Letters. 59: 2030-2033 |
| Schrader TO, Kasem M, Ren A, et al. (2016) Tetrahydroquinoline-based tricyclic amines as potent and selective agonists of the 5-HT2C receptor. Bioorganic & Medicinal Chemistry Letters |
| Fogerson SM, van Brummen AJ, Busch DJ, et al. (2016) Reducing synuclein accumulation improves neuronal survival after spinal cord injury. Experimental Neurology |
| Schrader TO, Kasem M, Sun Q, et al. (2016) Complementary asymmetric routes to fused tricyclic (R)-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinolines and (R)-1,2,3,4,5,5a,6,7-octahydro-[1,4]diazepino[1,2-a]quinolines Tetrahedron Letters. 57: 4730-4733 |
| Mallon M, Dutt S, Schrader T, et al. (2016) Protein Camouflage: Supramolecular Anion Recognition by Ubiquitin Chembiochem |
| Malishev R, Nandi S, Kolusheva S, et al. (2015) Toxicity Inhibitors Protect Lipid Membranes from Disruption by Aβ42. Acs Chemical Neuroscience |
| Lump E, Castellano LM, Meier C, et al. (2015) A molecular tweezer antagonizes seminal amyloids and HIV infection. Elife. 4 |
| Herzog G, Shmueli MD, Levy L, et al. (2015) The Lys-Specific Molecular Tweezer, CLR01, Modulates Aggregation of the Mutant p53 DNA Binding Domain and Inhibits Its Toxicity. Biochemistry. 54: 3729-38 |
| Lopes DH, Attar A, Nair G, et al. (2015) Molecular Tweezers Inhibit Islet Amyloid Polypeptide Assembly and Toxicity by a New Mechanism. Acs Chemical Biology. 10: 1555-69 |