Wolfgang Dohle
Affiliations: | 1999-2002 | Ludwig-Maximilians-Universität München, München, Bayern, Germany |
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"Wolfgang Dohle"Mean distance: 8.93 | S | N | B | C | P |
Parents
Sign in to add mentor| Paul Knochel | grad student | 1999-2002 | Universität München |
| Barry V. L. Potter | research scientist | Oxford |
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Publications
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| Dohle W, Su X, Mills SJ, et al. (2019) A synthetic cyclitol-nucleoside conjugate polyphosphate is a highly potent second messenger mimic. Chemical Science. 10: 5382-5390 |
| Nel M, Joubert AM, Dohle W, et al. (2018) Modes of cell death induced by tetrahydroisoquinoline-based analogs in MDA-MB-231 breast and A549 lung cancer cell lines. Drug Design, Development and Therapy. 12: 1881-1904 |
| Shen YC, Upadhyayula R, Cevallos S, et al. (2015) Targeted NF1 cancer therapeutics with multiple modes of action: small molecule hormone-like agents resembling the natural anticancer metabolite, 2-methoxyoestradiol. British Journal of Cancer. 113: 1158-67 |
| Dohle W, Leese MP, Jourdan FL, et al. (2014) Optimisation of tetrahydroisoquinoline-based chimeric microtubule disruptors. Chemmedchem. 9: 1783-93 |
| Leese MP, Jourdan FL, Major MR, et al. (2014) Synthesis, anti-tubulin and antiproliferative SAR of steroidomimetic dihydroisoquinolinones. Chemmedchem. 9: 798-812 |
| Dohle W, Leese MP, Jourdan FL, et al. (2014) Synthesis, antitubulin, and antiproliferative SAR of C3/C1-substituted tetrahydroisoquinolines. Chemmedchem. 9: 350-70 |
| Leese MP, Jourdan FL, Major MR, et al. (2014) Tetrahydroisoquinolinone-based steroidomimetic and chimeric microtubule disruptors. Chemmedchem. 9: 85-108, 1 |
| Leese MP, Jourdan F, Dohle W, et al. (2012) Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors. Acs Medicinal Chemistry Letters. 3: 5-9 |
| Jourdan F, Leese MP, Dohle W, et al. (2011) Structure-activity relationships of C-17-substituted estratriene-3-O-sulfamates as anticancer agents. Journal of Medicinal Chemistry. 54: 4863-79 |
| Jourdan F, Leese MP, Dohle W, et al. (2010) Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamate. Journal of Medicinal Chemistry. 53: 2942-51 |