Thomas Böttcher, Ph.D.
Affiliations: | 2014-2020 | Chemistry | University of Konstanz, Konstanz, Germany |
| 2020- | University of Vienna, Wien, Wien, Austria |
Area:
Chemical Biology, Natural Products, Enzyme InhibitorsGoogle:
"Thomas Böttcher"Mean distance: 8.71
Parents
Sign in to add mentor| Stephan Sieber | grad student | 2006-2009 | Ludwig Maximilian University Munich |
| Stephan Sieber | post-doc | 2010-2010 | Technical University of Munich |
| Jon C. Clardy | post-doc | 2011-2014 | Harvard Medical School |
Children
Sign in to add trainee| Michaela Prothiwa | grad student | University of Konstanz | |
| Sina Rütschlin | grad student | University of Konstanz | |
| Dávid Szamosvári | grad student | University of Konstanz |
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Publications
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| Mix AK, Nguyen THN, Schuhmacher T, et al. (2025) A quinolone N-oxide antibiotic selectively targets Neisseria gonorrhoeae via its toxin-antitoxin system. Nature Microbiology. 10: 939-957 |
| Pereira FC, Ge X, Kristensen JM, et al. (2024) The Parkinson's disease drug entacapone disrupts gut microbiome homoeostasis via iron sequestration. Nature Microbiology |
| Steuer J, Sinn M, Eble F, et al. (2024) Cooperative binding of bivalent ligands yields new insights into the guanidine-II riboswitch. Nar Genomics and Bioinformatics. 6: lqae132 |
| Ückert AK, Rütschlin S, Gutbier S, et al. (2023) Identification of the bacterial metabolite aerugine as potential trigger of human dopaminergic neurodegeneration. Environment International. 180: 108229 |
| Savchenko V, Szamosvári D, Bao Y, et al. (2023) Biosynthetic flexibility of Pseudomonas aeruginosa leads to hydroxylated 2-alkylquinolones with proinflammatory host response. Communications Chemistry. 6: 138 |
| Szamosvári D, Savchenko V, Badouin N, et al. (2023) Beyond iron: metal-binding activity of the quinolone signal-motif. Organic & Biomolecular Chemistry. 21: 5158-5163 |
| Klein K, Garkov D, Rütschlin S, et al. (2021) Corrigendum to: QSDB-a graphical Quorum Sensing Database. Database : the Journal of Biological Databases and Curation. 2021 |
| Klein K, Garkov D, Rütschlin S, et al. (2021) QSDB-a graphical Quorum Sensing Database. Database : the Journal of Biological Databases and Curation. 2021 |
| Prothiwa M, Filz V, Oehler S, et al. (2021) Inhibiting quinolone biosynthesis of . Chemical Science. 12: 6908-6912 |
| Peñalver L, Schmid P, Szamosvári D, et al. (2020) A ligand selection strategy identifies chemical probes targeting the proteases of SARS-CoV-2. Angewandte Chemie (International Ed. in English) |