Thomas Böttcher, Ph.D.

Affiliations: 
2014-2020 Chemistry University of Konstanz, Konstanz, Germany 
 2020- University of Vienna, Wien, Wien, Austria 
Area:
Chemical Biology, Natural Products, Enzyme Inhibitors
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"Thomas Böttcher"
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Publications

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Mix AK, Nguyen THN, Schuhmacher T, et al. (2025) A quinolone N-oxide antibiotic selectively targets Neisseria gonorrhoeae via its toxin-antitoxin system. Nature Microbiology. 10: 939-957
Pereira FC, Ge X, Kristensen JM, et al. (2024) The Parkinson's disease drug entacapone disrupts gut microbiome homoeostasis via iron sequestration. Nature Microbiology
Steuer J, Sinn M, Eble F, et al. (2024) Cooperative binding of bivalent ligands yields new insights into the guanidine-II riboswitch. Nar Genomics and Bioinformatics. 6: lqae132
Ückert AK, Rütschlin S, Gutbier S, et al. (2023) Identification of the bacterial metabolite aerugine as potential trigger of human dopaminergic neurodegeneration. Environment International. 180: 108229
Savchenko V, Szamosvári D, Bao Y, et al. (2023) Biosynthetic flexibility of Pseudomonas aeruginosa leads to hydroxylated 2-alkylquinolones with proinflammatory host response. Communications Chemistry. 6: 138
Szamosvári D, Savchenko V, Badouin N, et al. (2023) Beyond iron: metal-binding activity of the quinolone signal-motif. Organic & Biomolecular Chemistry. 21: 5158-5163
Klein K, Garkov D, Rütschlin S, et al. (2021) Corrigendum to: QSDB-a graphical Quorum Sensing Database. Database : the Journal of Biological Databases and Curation. 2021
Klein K, Garkov D, Rütschlin S, et al. (2021) QSDB-a graphical Quorum Sensing Database. Database : the Journal of Biological Databases and Curation. 2021
Prothiwa M, Filz V, Oehler S, et al. (2021) Inhibiting quinolone biosynthesis of . Chemical Science. 12: 6908-6912
Peñalver L, Schmid P, Szamosvári D, et al. (2020) A ligand selection strategy identifies chemical probes targeting the proteases of SARS-CoV-2. Angewandte Chemie (International Ed. in English)
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