Reymundo Antonio Villa
Affiliations: | 2014- | Boston Biomedical |
Website:
https://www.linkedin.com/pub/reymundo-villa/6b/53/159Google:
"Reymundo Villa"Mean distance: 7.7 | S | N | B | C | P |
Parents
Sign in to add mentor| Ohyun Kwon | grad student | 2001-2008 | UCLA | |
| (Phosphine catalyzed [4+2] annulation in the total synthesis of corynantheine indole alkaloids.) | ||||
| Michael D. Burkart | post-doc | 2008-2013 | UCSD | |
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Publications
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| Kumar D, Kashyap MK, Yu Z, et al. (2022) Modulation of RNA splicing associated with Wnt signaling pathway using FD-895 and pladienolide B. Aging. 14: 2081-2100 |
| Crews LA, Balaian L, Delos Santos NP, et al. (2016) RNA Splicing Modulation Selectively Impairs Leukemia Stem Cell Maintenance in Secondary Human AML. Cell Stem Cell |
| Kumar D, Kashyap MK, La Clair JJ, et al. (2016) Selectivity in Small Molecule Splicing Modulation. Acs Chemical Biology |
| Crews LA, Balaian L, Leu HS, et al. (2016) Abstract 915: RNA processing signatures of normal versus malignant progenitor cell aging predict leukemia stem cell sensitivity to RNA splicing modulation Cancer Research. 76: 915-915 |
| Kashyap MK, Kumar D, Villa R, et al. (2015) Targeting the spliceosome in chronic lymphocytic leukemia with the macrolides FD-895 and pladienolide-B. Haematologica. 100: 945-54 |
| Crews LA, Balaian L, Leu H, et al. (2015) RNA Splicing Modulation Impairs Acute Myeloid Leukemia Stem Cell Maintenance Blood. 126: 567-567 |
| Villa R, Kashyap MK, Kumar D, et al. (2013) Stabilized cyclopropane analogs of the splicing inhibitor FD-895. Journal of Medicinal Chemistry. 56: 6576-82 |
| Rothmann M, Kang M, Villa R, et al. (2013) Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A. Journal of the American Chemical Society. 135: 5962-5 |
| Kumar D, Kashyap MK, Spaanderman I, et al. (2013) A Cyclopropane-Derived Stable Analog Of Fd-895 Induces Apoptosis and Inhibition Of mRNA Splicing In Lymphoma and Chronic Lymphocytic Leukemia: A Novel Therapeutic Approach Blood. 122: 2884-2884 |
| Villa R, Mandel AL, Jones BD, et al. (2012) Structure of FD-895 revealed through total synthesis. Organic Letters. 14: 5396-9 |