Margie Mattmann
Affiliations: | 2010 | University of Wisconsin, Madison, Madison, WI |
Area:
synthesis of biologically active moleculesGoogle:
"Margie Mattmann"Mean distance: 7.73 | S | N | B | C | P |
Parents
Sign in to add mentor| Helen Elizabeth Blackwell | grad student | 2010 | UW Madison | |
| (Design, synthesis, and evaluation of small molecules for the modulation of quorum sensing in Pseudomonas aeruginosa.) | ||||
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Publications
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| Eibergen NR, Moore JD, Mattmann ME, et al. (2015) Potent and Selective Modulation of the RhlR Quorum Sensing Receptor by Using Non-native Ligands: An Emerging Target for Virulence Control in Pseudomonas aeruginosa. Chembiochem : a European Journal of Chemical Biology. 16: 2348-56 |
| Jalan-Sakrikar N, Field JR, Klar R, et al. (2014) Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7. Acs Chemical Neuroscience. 5: 1221-37 |
| Blobaum AL, Bridges TM, Byers FW, et al. (2013) Heterotropic activation of the midazolam hydroxylase activity of CYP3A by a positive allosteric modulator of mGlu5: in vitro to in vivo translation and potential impact on clinically relevant drug-drug interactions. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 2066-75 |
| Lindemann A, Pessi G, Schaefer AL, et al. (2011) Isovaleryl-homoserine lactone, an unusual branched-chain quorum-sensing signal from the soybean symbiont Bradyrhizobium japonicum. Proceedings of the National Academy of Sciences of the United States of America. 108: 16765-70 |
| Mattmann ME, Shipway PM, Heth NJ, et al. (2011) Potent and selective synthetic modulators of a quorum sensing repressor in Pseudomonas aeruginosa identified from second-generation libraries of N-acylated L-homoserine lactones. Chembiochem : a European Journal of Chemical Biology. 12: 942-9 |
| Mattmann ME, Blackwell HE. (2010) Small molecules that modulate quorum sensing and control virulence in Pseudomonas aeruginosa. The Journal of Organic Chemistry. 75: 6737-46 |
| Geske GD, Mattmann ME, Blackwell HE. (2008) Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators. Bioorganic & Medicinal Chemistry Letters. 18: 5978-81 |
| Geske GD, O'Neill JC, Miller DM, et al. (2008) Comparative analyses of N-acylated homoserine lactones reveal unique structural features that dictate their ability to activate or inhibit quorum sensing. Chembiochem : a European Journal of Chemical Biology. 9: 389-400 |
| Mattmann ME, Geske GD, Worzalla GA, et al. (2008) Synthetic ligands that activate and inhibit a quorum-sensing regulator in Pseudomonas aeruginosa. Bioorganic & Medicinal Chemistry Letters. 18: 3072-5 |
| Geske GD, O'Neill JC, Miller DM, et al. (2007) Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action. Journal of the American Chemical Society. 129: 13613-25 |