Matt Holt
Affiliations: | 2014 | Princeton University, Princeton, NJ |
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| Dai S, Holt MV, Horton JR, et al. (2020) Characterization of SETD3 methyltransferase mediated protein methionine methylation. The Journal of Biological Chemistry |
| Holt MV, Wang T, Young NL. (2019) High-Throughput Quantitative Top-Down Proteomics: Histone H4. Journal of the American Society For Mass Spectrometry |
| Wang T, Holt MV, Young NL. (2018) Early Butyrate Induced Acetylation of Histone H4 is Proteoform Specific and Linked to Methylation State. Epigenetics |
| Wang T, Holt MV, Young NL. (2018) The histone H4 proteoform dynamics in response to SUV4-20 inhibition reveals single molecule mechanisms of inhibitor resistance. Epigenetics & Chromatin. 11: 29 |
| Jiang T, Hoover ME, Holt MV, et al. (2018) Middle-Down Characterization of the Cell Cycle Dependence of Histone H4 Post-Translational Modifications and Proteoforms. Proteomics. e1700442 |
| Holt MV, Wang T, Young NL. (2017) Recent Advances in Understanding Histone Modification Events Current Molecular Biology Reports. 3: 11-17 |
| Zhou L, Holt MT, Ohashi N, et al. (2016) Evidence that ubiquitylated H2B corrals hDot1L on the nucleosomal surface to induce H3K79 methylation. Nature Communications. 7: 10589 |
| Holt MT, David Y, Pollock S, et al. (2015) Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin. Proceedings of the National Academy of Sciences of the United States of America |
| Holt M, Muir T. (2015) Application of the protein semisynthesis strategy to the generation of modified chromatin. Annual Review of Biochemistry. 84: 265-90 |
| Whitcomb SJ, Fierz B, McGinty RK, et al. (2012) Histone monoubiquitylation position determines specificity and direction of enzymatic cross-talk with histone methyltransferases Dot1L and PRC2. The Journal of Biological Chemistry. 287: 23718-25 |