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Matthew Clark, Ph.D.

Affiliations: 
1986-1991 Chemistry Cornell University, Ithaca, NY, United States 
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"Matthew Clark"
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Parents

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Bruce Ganem grad student 1996-2001 Cornell
Stephen James Lippard post-doc 2001-2004 MIT
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Publications

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Ding Y, Franklin GJ, DeLorey JL, et al. (2016) Design and Synthesis of Biaryl DNA-Encoded Libraries. Acs Combinatorial Science
Ding Y, O'Keefe H, DeLorey JL, et al. (2015) Discovery of Potent and Selective Inhibitors for ADAMTS-4 through DNA-Encoded Library Technology (ELT). Acs Medicinal Chemistry Letters. 6: 888-93
Litovchick A, Dumelin CE, Habeshian S, et al. (2015) Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library. Scientific Reports. 5: 10916
Yang H, Medeiros PF, Raha K, et al. (2015) Discovery of a Potent Class of PI3Kα Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT). Acs Medicinal Chemistry Letters. 6: 531-6
Keefe AD, Clark MA, Hupp CD, et al. (2015) Chemical ligation methods for the tagging of DNA-encoded chemical libraries. Current Opinion in Chemical Biology. 26: 80-8
Ding Y, Clark MA. (2015) Robust Suzuki-Miyaura cross-coupling on DNA-linked substrates. Acs Combinatorial Science. 17: 1-4
Deng H, Zhou J, Sundersingh FS, et al. (2015) Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library Acs Medicinal Chemistry Letters. 6: 919-924
Litovchick A, Clark MA, Keefe AD. (2014) Universal strategies for the DNA-encoding of libraries of small molecules using the chemical ligation of oligonucleotide tags. Artificial Dna, Pna & Xna. 5: e27896
Encinas L, O'Keefe H, Neu M, et al. (2014) Encoded library technology as a source of hits for the discovery and lead optimization of a potent and selective class of bactericidal direct inhibitors of Mycobacterium tuberculosis InhA. Journal of Medicinal Chemistry. 57: 1276-88
Götz AW, Clark MA, Walker RC. (2014) An extensible interface for QM/MM molecular dynamics simulations with AMBER. Journal of Computational Chemistry. 35: 95-108
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