Jason Ray Thomas

Affiliations: 
2007 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
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Paul J. Hergenrother grad student 2007 UIUC
 (Towards the therapies of tomorrow: Selective RNA binding small molecules and cytoprotective strategies for ROS-mediated disease states.)
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Schröder M, Renatus M, Liang X, et al. (2024) DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nature Communications. 15: 275
Ross NT, Lohmann F, Carbonneau S, et al. (2019) CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma. Nature Chemical Biology
Palacino J, Swalley SE, Song C, et al. (2015) SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice. Nature Chemical Biology. 11: 511-7
Thomas JR, Hergenrother PJ. (2008) Targeting RNA with small molecules. Chemical Reviews. 108: 1171-224
Thomas JR, Liu X, Hergenrother PJ. (2006) Biochemical and thermodynamic characterization of compounds that bind to RNA hairpin loops: toward an understanding of selectivity. Biochemistry. 45: 10928-38
Thomas JR, Liu X, Hergenrother PJ. (2005) Size-specific ligands for RNA hairpin loops. Journal of the American Chemical Society. 127: 12434-5
Thomas JR, DeNap JC, Wong ML, et al. (2005) The relationship between aminoglycosides' RNA binding proclivity and their antiplasmid effect on an IncB plasmid. Biochemistry. 44: 6800-8
Denap JC, Thomas JR, Musk DJ, et al. (2004) Combating drug-resistant bacteria: small molecule mimics of plasmid incompatibility as antiplasmid compounds. Journal of the American Chemical Society. 126: 15402-4
Liu X, Thomas JR, Hergenrother PJ. (2004) Deoxystreptamine dimers bind to RNA hairpin loops. Journal of the American Chemical Society. 126: 9196-7
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