Christopher Lohans, Ph.D.
Affiliations: | 2014 | University of Alberta, Edmonton, Alberta, Canada |
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"Christopher Lohans"Mean distance: 8.05 | S | N | B | C | P |
Parents
Sign in to add mentorJohn C. Vederas | grad student | 2014 | University of Alberta |
Christopher J. Schofield | post-doc | 2015- | Oxford |
Children
Sign in to add traineeMontserrat Mora Ochomogo | grad student | 2021- | Queens University, Ontario |
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Publications
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Lang PA, Raj R, Tumber A, et al. (2022) Studies on enmetazobactam clarify mechanisms of widely used β-lactamase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 119: e2117310119 |
Lucic A, Hinchliffe P, Malla TR, et al. (2021) Faropenem reacts with serine and metallo-β-lactamases to give multiple products. European Journal of Medicinal Chemistry. 215: 113257 |
Aertker KMJ, Chan HTH, Lohans CT, et al. (2020) Analysis of β-lactone formation by clinically observed carbapenemases informs on a novel antibiotic resistance mechanism. The Journal of Biological Chemistry |
Liu T, Abboud MI, Chowdhury R, et al. (2020) Biochemical and biophysical analyses of hypoxia sensing prolyl hydroxylases from Dictyostelium discoideum and Toxoplasma gondii. The Journal of Biological Chemistry |
Cochrane SA, Lohans CT. (2020) Breaking down the cell wall: Strategies for antibiotic discovery targeting bacterial transpeptidases. European Journal of Medicinal Chemistry. 194: 112262 |
Holt-Martyn J, Chowdhury R, Tumber A, et al. (2019) Structure-Activity Relationship and Crystallographic Studies On 4-Hydroxypyrimidine HIF Prolyl Hydroxylase Domain Inhibitors. Chemmedchem |
Shaikh F, Zhao Y, Alvarez L, et al. (2019) Correction to "Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library". Journal of Medicinal Chemistry |
Lohans CT, Freeman EI, Groesen EV, et al. (2019) Mechanistic Insights into β-Lactamase-Catalysed Carbapenem Degradation Through Product Characterisation. Scientific Reports. 9: 13608 |
de Munnik M, Lohans CT, Lang PA, et al. (2019) Targeting the Mycobacterium tuberculosis transpeptidase Ldt with cysteine-reactive inhibitors including ebselen. Chemical Communications (Cambridge, England) |
de Munnik M, Lohans CT, Langley GW, et al. (2019) A Fluorescence-based Assay for Screening β-Lactams Targeting the Mycobacterium tuberculosis Transpeptidase LdtMt2. Chembiochem : a European Journal of Chemical Biology |