Darren Derksen, Ph.D.
Affiliations: | 2007 | University of Alberta, Edmonton, Alberta, Canada | |
| 2014- | Chemistry | University of Calgary, Calgary, Alberta, Canada |
Area:
Medicinal ChemistryWebsite:
http://people.ucalgary.ca/~dderksen/Google:
"Darren Derksen"Mean distance: 8.54 | S | N | B | C | P |
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Publications
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| Brownsey DK, Rowley BC, Gorobets E, et al. (2022) Identification of ligand linkage vectors for the development of p300/CBP degraders. Rsc Medicinal Chemistry. 13: 726-730 |
| Gorobets E, Papatzimas JW, Dourado J, et al. (2022) A vinylogous Norrish reaction as a strategy for light-mediated ring expansion. Chemical Communications (Cambridge, England). 58: 2910-2913 |
| Dutta I, Dieters-Castator D, Papatzimas JW, et al. (2020) ADAM protease inhibition overcomes resistance of breast cancer stem-like cells to γδ T cell immunotherapy. Cancer Letters |
| Papatzimas JW, Gorobets E, Maity R, et al. (2019) From Inhibition to Degradation: Targeting the Anti-apoptotic Protein Myeloid Cell Leukemia 1 (MCL1). Journal of Medicinal Chemistry |
| Huang Z, Derksen DJ, Vederas JC. (2010) Preparation and use of cysteine orthoesters for solid-supported synthesis of peptides. Organic Letters. 12: 2282-5 |
| Derksen DJ, Boudreau MA, Vederas JC. (2008) Hydrophobic interactions as substitutes for a conserved disulfide linkage in the type IIa bacteriocins, leucocin A and pediocin PA-1. Chembiochem : a European Journal of Chemical Biology. 9: 1898-901 |
| van Belkum MJ, Derksen DJ, Franz CM, et al. (2007) Structure function relationship of inducer peptide pheromones involved in bacteriocin production in Carnobacterium maltaromaticum and Enterococcus faecium. Microbiology (Reading, England). 153: 3660-6 |
| Pattabiraman VR, Stymiest JL, Derksen DJ, et al. (2007) Multiple on-resin olefin metathesis to form ring-expanded analogues of the lantibiotic peptide, lacticin 3147 A2. Organic Letters. 9: 699-702 |
| Derksen DJ, Stymiest JL, Vederas JC. (2006) Antimicrobial leucocin analogues with a disulfide bridge replaced by a carbocycle or by noncovalent interactions of allyl glycine residues. Journal of the American Chemical Society. 128: 14252-3 |
| Gursky LJ, Martin NI, Derksen DJ, et al. (2006) Production of piscicolin 126 by Carnobacterium maltaromaticum UAL26 is controlled by temperature and induction peptide concentration. Archives of Microbiology. 186: 317-25 |