Shaun Michael McLoughlin

Affiliations: 
2005 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
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"Shaun McLoughlin"
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Neil  L. Kelleher grad student 2005 UIUC
 (Mass spectrometry and thiotemplate assembly: Unique insights into the production of natural products on >100 kDa enzymes.)
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Warder SE, McLoughlin SM, Hansen TM, et al. (2016) Abstract 3059: Discovery of BET family proteins as cancer targets using phenotypic-based profiling and affinity capture mass spectrometry Cancer Research. 76: 3059-3059
Zhang HM, McLoughlin SM, Frausto SD, et al. (2010) Simultaneous reduction and digestion of proteins with disulfide bonds for hydrogen/deuterium exchange monitored by mass spectrometry. Analytical Chemistry. 82: 1450-4
Warder SE, Tucker LA, McLoughlin SM, et al. (2008) Discovery, identification, and characterization of candidate pharmacodynamic markers of methionine aminopeptidase-2 inhibition. Journal of Proteome Research. 7: 4807-20
McLoughlin SM, Kelleher NL. (2005) Monitoring multiple active sites on thiotemplate enzymes in parallel: a molecular movie of yersiniabactin bioassembly. Journal of the American Chemical Society. 127: 14984-5
McLoughlin SM, Mazur MT, Miller LM, et al. (2005) Chemoenzymatic approaches for streamlined detection of active site modifications on thiotemplate assembly lines using mass spectrometry. Biochemistry. 44: 14159-69
Yin J, Straight PD, McLoughlin SM, et al. (2005) Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase. Proceedings of the National Academy of Sciences of the United States of America. 102: 15815-20
Miller LM, Mazur MT, McLoughlin SM, et al. (2005) Parallel interrogation of covalent intermediates in the biosynthesis of gramicidin S using high-resolution mass spectrometry. Protein Science : a Publication of the Protein Society. 14: 2702-12
Gatto GJ, McLoughlin SM, Kelleher NL, et al. (2005) Elucidating the substrate specificity and condensation domain activity of FkbP, the FK520 pipecolate-incorporating enzyme. Biochemistry. 44: 5993-6002
McLoughlin SM, Kelleher NL. (2004) Kinetic and regiospecific interrogation of covalent intermediates in the nonribosomal peptide synthesis of yersiniabactin. Journal of the American Chemical Society. 126: 13265-75
Tseng CC, McLoughlin SM, Kelleher NL, et al. (2004) Role of the active site cysteine of DpgA, a bacterial type III polyketide synthase. Biochemistry. 43: 970-80
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