Jeffrey K. Tong
Affiliations: | 2000 | Harvard University, Cambridge, MA, United States |
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"Jeffrey Tong"Mean distance: 7.32 | S | N | B | C | P |
Parents
Sign in to add mentor| Stuart L. Schreiber | grad student | 2000 | Harvard | |
| (Biochemical and genomic studies of histone deacetylases.) | ||||
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Publications
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| Song D, Chaerkady R, Tan AC, et al. (2008) Antitumor activity and molecular effects of the novel heat shock protein 90 inhibitor, IPI-504, in pancreatic cancer. Molecular Cancer Therapeutics. 7: 3275-84 |
| Sydor JR, Normant E, Pien CS, et al. (2006) Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90. Proceedings of the National Academy of Sciences of the United States of America. 103: 17408-13 |
| Ge J, Normant E, Porter JR, et al. (2006) Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90. Journal of Medicinal Chemistry. 49: 4606-15 |
| Tong JK. (2002) Dissecting histone deacetylase function. Chemistry & Biology. 9: 668-70 |
| Pflum MK, Tong JK, Lane WS, et al. (2001) Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation. The Journal of Biological Chemistry. 276: 47733-41 |
| You A, Tong JK, Grozinger CM, et al. (2001) CoREST is an integral component of the CoREST- human histone deacetylase complex. Proceedings of the National Academy of Sciences of the United States of America. 98: 1454-8 |
| Bernstein BE, Tong JK, Schreiber SL. (2000) Genomewide studies of histone deacetylase function in yeast. Proceedings of the National Academy of Sciences of the United States of America. 97: 13708-13 |
| Hardwick JS, Kuruvilla FG, Tong JK, et al. (1999) Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins. Proceedings of the National Academy of Sciences of the United States of America. 96: 14866-70 |
| Hardwick JS, Tong JK, Schreiber SL. (1999) The transcriptional profile of Saccharomyces cerevisiae exposed to rapamycin mimics the profile induced by amino acid starvation Nature Genetics. 23: 49-49 |
| Stockwell BR, Hardwick JS, Tong JK, et al. (1999) Chemical genetic and genomic approaches reveal a role for copper in specific gene activation [19] Journal of the American Chemical Society. 121: 10662-10663 |