Le Cong
Affiliations: | 2014 | Biology: Medical Sciences, Division of | Harvard University, Cambridge, MA, United States |
| 2017 | Biology, Bioengineering, McGovern Institute | Massachusetts Institute of Technology, Cambridge, MA, United States | |
| 2017 | Zhang Lab, Regev Lab | Broad Institute (MIT/Harvard) | |
| 2018- | Pathology, Genetics, Wu Tsai Neuroscience Institute | Stanford University, Palo Alto, CA |
Website:
https://profiles.stanford.edu/186687Google:
"Le Cong"Mean distance: 9.43 | S | N | B | C | P |
Parents
Sign in to add mentor| Feng Zhang | grad student | MIT (Neurotree) | ||
| George M. Church | grad student | 2014 | Harvard | |
| (Genome Engineering Technology and Its Application in Mammalian Cells.) | ||||
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Publications
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| Marsiglia J, Vaalavirta K, Knight E, et al. (2024) Computationally guided high-throughput engineering of an anti-CRISPR protein for precise genome editing in human cells. Cell Reports Methods. 4: 100882 |
| Hebert JD, Xu H, Tang YJ, et al. (2024) Modeling the genomic complexity of human cancer using Cas12a mice. Biorxiv : the Preprint Server For Biology |
| Wang X, Xu G, Johnson WA, et al. (2023) Long sequence insertion via CRISPR/Cas gene-editing with transposase, recombinase, and integrase. Current Opinion in Biomedical Engineering. 28 |
| Wang C, Xia Q, Zhang Q, et al. (2022) CRISPR-Cas12a System With Synergistic Phage Recombination Proteins for Multiplex Precision Editing in Human Cells. Frontiers in Cell and Developmental Biology. 9: 719705 |
| Wang C, Qu Y, Cheng JKW, et al. (2022) dCas9-based gene editing for cleavage-free genomic knock-in of long sequences. Nature Cell Biology. 24: 268-278 |
| Wang C, Cheng JKW, Zhang Q, et al. (2021) Microbial single-strand annealing proteins enable CRISPR gene-editing tools with improved knock-in efficiencies and reduced off-target effects. Nucleic Acids Research |
| Nidetz NF, McGee MC, Tse LV, et al. (2019) Adeno-associated viral vector-mediated immune responses: Understanding barriers to gene delivery. Pharmacology & Therapeutics. 107453 |
| Luan B, Xu G, Feng M, et al. (2019) Combined Computational-Experimental Approach to Explore Molecular Mechanism of SaCas9 with Broadened DNA Targeting Range. Journal of the American Chemical Society |
| Cleary B, Cong L, Cheung A, et al. (2017) Efficient Generation of Transcriptomic Profiles by Random Composite Measurements. Cell |
| Cong L. (2017) CRISPR: Groundbreaking technology for RNA-guided genome engineering. Analytical Biochemistry |