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Patrick Knerr, Ph.D.

Affiliations: 
2013 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
 2013- DuPont 
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Wilfred A. van der Donk grad student 2013 UIUC
 (Chemical and chemoenzymatic syntheses of lantibiotics and other bioactive cyclic peptides.)
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Publications

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Knerr PJ, Mowery SA, Douros JD, et al. (2022) Next generation GLP-1/GIP/glucagon triple agonists normalize body weight in obese mice. Molecular Metabolism. 101533
Huang Y, Reis ES, Knerr PJ, et al. (2014) Conjugation to albumin-binding molecule tags as a strategy to improve both efficacy and pharmacokinetic properties of the complement inhibitor compstatin. Chemmedchem. 9: 2223-6
Huang Y, Reis ES, Knerr PJ, et al. (2014) Conjugation to albumin-binding molecule tags as a strategy to improve both efficacy and pharmacokinetic properties of the complement inhibitor compstatin Chemmedchem. 9: 2223-2226
Knerr PJ, Van Der Donk WA. (2013) Chemical synthesis of the lantibiotic lacticin 481 reveals the importance of lanthionine stereochemistry Journal of the American Chemical Society. 135: 7094-7097
Knerr PJ, Oman TJ, Garcia De Gonzalo CV, et al. (2012) Non-proteinogenic amino acids in lacticin 481 analogues result in more potent inhibition of peptidoglycan transglycosylation Acs Chemical Biology. 7: 1791-1795
Knerr PJ, Van Der Donk WA. (2012) Chemical synthesis and biological activity of analogues of the lantibiotic epilancin 15X Journal of the American Chemical Society. 134: 7648-7651
Oman TJ, Knerr PJ, Bindman NA, et al. (2012) An engineered lantibiotic synthetase that does not require a leader peptide on its substrate Journal of the American Chemical Society. 134: 6952-6955
Knerr PJ, Van Der Donk WA. (2012) Discovery, biosynthesis, and engineering of lantipeptides Annual Review of Biochemistry. 81: 479-505
Knerr PJ, Tzekou A, Ricklin D, et al. (2011) Synthesis and activity of thioether-containing analogues of the complement inhibitor compstatin Acs Chemical Biology. 6: 753-760
Micklitsch CM, Knerr PJ, Branco MC, et al. (2011) Zinc-triggered hydrogelation of a self-assembling β-hairpin peptide. Angewandte Chemie (International Ed. in English). 50: 1577-9
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