Wendell A. Lim - Related publications

1996- Cellular and Molecular Pharmacology University of California, San Francisco, San Francisco, CA 
Cellular Signaling Systems
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2021 Woodall NB, Weinberg Z, Park J, Busch F, Johnson RS, Feldbauer MJ, Murphy M, Ahlrichs M, Yousif I, MacCoss MJ, Wysocki VH, El-Samad H, Baker D. De novo design of tyrosine and serine kinase-driven protein switches. Nature Structural & Molecular Biology. 28: 762-770. PMID 34518698 DOI: 10.1038/s41594-021-00649-8   
2021 Chen SJ, Bi YH, Zhang LH. Systematic analysis of the potential off-target activities of osimertinib by computational target fishing. Anti-Cancer Drugs. PMID 34459459 DOI: 10.1097/CAD.0000000000001229   
2021 Mysore VP, Zhou ZW, Ambrogio C, Li L, Kapp JN, Lu C, Wang Q, Tucker MR, Okoro JJ, Nagy-Davidescu G, Bai X, Plückthun A, Jänne PA, Westover KD, Shan Y, et al. A structural model of a Ras-Raf signalosome. Nature Structural & Molecular Biology. 28: 847-857. PMID 34625747 DOI: 10.1038/s41594-021-00667-6   
2021 Limaye AJ, Bendzunas GN, Kennedy EJ. Targeted disruption of PKC from AKAP signaling complexes. Rsc Chemical Biology. 2: 1227-1231. PMID 34458835 DOI: 10.1039/d1cb00106j   
2021 Carrasco-Navarro U, Aguirre J. HO Induces Major Phosphorylation Changes in Critical Regulators of Signal Transduction, Gene Expression, Metabolism and Developmental Networks in . Journal of Fungi (Basel, Switzerland). 7. PMID 34436163 DOI: 10.3390/jof7080624   
2021 Sanchez-Garrido J, Shenoy AR. Regulation and repurposing of nutrient sensing and autophagy in innate immunity. Autophagy. 17: 1571-1591. PMID 32627660 DOI: 10.1080/15548627.2020.1783119   
2021 Luci C, Vieira E, Bourinet M, Rousseau D, Bonnafous S, Patouraux S, Lefevre L, Larbret F, Prod'homme V, Iannelli A, Tran A, Anty R, Bailly-Maitre B, Deckert M, Gual P. SYK-3BP2 Pathway Activity in Parenchymal and Myeloid Cells Is a Key Pathogenic Factor in Metabolic Steatohepatitis. Cellular and Molecular Gastroenterology and Hepatology. PMID 34411785 DOI: 10.1016/j.jcmgh.2021.08.004   
2021 Yeung W, Kwon A, Taujale R, Bunn C, Venkat A, Kannan N. Evolution of functional diversity in the holozoan tyrosine kinome. Molecular Biology and Evolution. PMID 34515793 DOI: 10.1093/molbev/msab272   
2021 Cabarca S, Frazão de Souza M, Albert de Oliveira A, Vignoli Muniz GS, Lamy MT, Vinicius Dos Reis C, Takarada J, Effer B, Souza LS, Iriarte de la Torre L, Couñago R, Pinto Oliveira CL, Balan A. Structure of the PknF and conformational changes induced in forkhead-associated regulatory domains. Current Research in Structural Biology. 3: 165-178. PMID 34382010 DOI: 10.1016/j.crstbi.2021.07.001   
2021 Zheng X, Su H, Wang L, Yao R, Ma Y, Bai L, Wang Y, Guo X, Wang Z. Phosphoproteomics Analysis Reveals a Pivotal Mechanism Related to Amino Acid Signals in Goat Fetal Fibroblast. Frontiers in Veterinary Science. 8: 685548. PMID 34414225 DOI: 10.3389/fvets.2021.685548   
2021 Wu C, Yang H, Han C, Wang Q, Zhang H, Huang T, Mao W, Tang C, Zhao W, Zhu Z, Xu J, Yang W. Quyu Shengxin Decoction Alleviates DSS-Induced Ulcerative Colitis in Mice by Suppressing RIP1/RIP3/NLRP3 Signalling. Evidence-Based Complementary and Alternative Medicine : Ecam. 2021: 6682233. PMID 34462641 DOI: 10.1155/2021/6682233   
2021 Kondo Y, Paul JW, Subramaniam S, Kuriyan J. New insights into Raf regulation from structural analyses. Current Opinion in Structural Biology. 71: 223-231. PMID 34454301 DOI: 10.1016/j.sbi.2021.07.005   
2021 Karl K, Hristova K. Pondering the mechanism of receptor tyrosine kinase activation: The case for ligand-specific dimer microstate ensembles. Current Opinion in Structural Biology. 71: 193-199. PMID 34399300 DOI: 10.1016/j.sbi.2021.07.003   
2021 Ma J, Ren Y, Zhang JN, Lin L, Zhang YL. [Analysis on targets of regulating Qi and activating blood based on activity spectrum of targets]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 46: 3970-3979. PMID 34472274 DOI: 10.19540/j.cnki.cjcmm.20210303.401   
2021 Zhang A, Pompeo F, Galinier A. Overview of protein phosphorylation in bacteria with a main focus on unusual protein kinases in Bacillus subtilis. Research in Microbiology. 103871. PMID 34500011 DOI: 10.1016/j.resmic.2021.103871   
2021 Rho SB, Lee KW, Lee SH, Byun HJ, Kim BR, Lee CH. Novel Anti-Angiogenic and Anti-Tumour Activities of the N-Terminal Domain of NOEY2 via Binding to VEGFR-2 in Ovarian Cancer. Biomolecules & Therapeutics. 29: 506-518. PMID 34462379 DOI: 10.4062/biomolther.2021.121   
2021 Muñoz-Muñoz PLA, Mares-Alejandre RE, Meléndez-López SG, Ramos-Ibarra MA. Bioinformatic Analysis of Two TOR (Target of Rapamycin)-Like Proteins Encoded by Revealed Structural Similarities with Functional Homologs. Genes. 12. PMID 34440318 DOI: 10.3390/genes12081139   
2021 Nosratpour S, Ndiaye K. Ankyrin-repeat and SOCS box-containing protein 9 (ASB9) regulates ovarian granulosa cells function and MAPK signaling. Molecular Reproduction and Development. PMID 34476862 DOI: 10.1002/mrd.23532   
2021 Zheng CR, Singh A, Libby A, Silver PA, Libby EA. Modular and Single-Cell Sensors of Bacterial Ser/Thr Kinase Activity. Acs Synthetic Biology. PMID 34463482 DOI: 10.1021/acssynbio.1c00250   
2021 Wang W, Dai Z, Li J, Ouyang J, Li T, Zeng B, Kang L, Jia K, Xi Z, Jia W. A Method for Assaying of Protein Kinase Activity In Vivo and Its Use in Studies of Signal Transduction in Strawberry Fruit Ripening. International Journal of Molecular Sciences. 22. PMID 34638834 DOI: 10.3390/ijms221910495   
2021 Zhu S, Fu Q, Xu F, Zheng H, Yu F. New paradigms in cell adaptation: decades of discoveries on the CrRLK1L receptor kinase signalling network. The New Phytologist. PMID 34424552 DOI: 10.1111/nph.17683   
2021 Aledavood E, Forte A, Estarellas C, Javier Luque F. Structural basis of the selective activation of enzyme isoforms: Allosteric response to activators of β1- and β2-containing AMPK complexes. Computational and Structural Biotechnology Journal. 19: 3394-3406. PMID 34194666 DOI: 10.1016/j.csbj.2021.05.056   
2021 Chan TY, Egbert CM, Maxson JE, Siddiqui A, Larsen LJ, Kohler K, Balasooriya ER, Pennington KL, Tsang TM, Frey M, Soderblom EJ, Geng H, Müschen M, Forostyan TV, Free S, et al. TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth. Nature Communications. 12: 5337. PMID 34504101 DOI: 10.1038/s41467-021-25622-3   
2021 Geng Q, Liu B, Zhao PC, Xiong YB, Li L, Yi JF, Lyu C. [Molecular mechanism of Fagopyri Dibotryis Rhizoma in treatment of acute lung injury based on network pharmacology and in vitro experiments]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 46: 4816-4823. PMID 34581093 DOI: 10.19540/j.cnki.cjcmm.20210524.401   
2021 Karamafrooz A, Brennan J, Thomas DD, Parker LL. Integrated Phosphoproteomics for Identifying Substrates of Human Protein Kinase A () and Its Oncogenic Mutant 1. Journal of Proteome Research. PMID 34436901 DOI: 10.1021/acs.jproteome.1c00500   
2021 Gerritsen JS, White FM. Phosphoproteomics: a valuable tool for uncovering molecular signaling in cancer cells. Expert Review of Proteomics. PMID 34468274 DOI: 10.1080/14789450.2021.1976152   
2021 Waschbüsch D, Berndsen K, Lis P, Knebel A, Lam YP, Alessi DR, Khan AR. Structural basis for the specificity of PPM1H phosphatase for Rab GTPases. Embo Reports. e52675. PMID 34580980 DOI: 10.15252/embr.202152675   
2021 Ma X, Verweij EWE, Siderius M, Leurs R, Vischer HF. Identification of TSPAN4 as Novel Histamine H Receptor Interactor. Biomolecules. 11. PMID 34439793 DOI: 10.3390/biom11081127   
2021 Mathis CL, Barrios AM. Histidine phosphorylation in metalloprotein binding sites. Journal of Inorganic Biochemistry. 225: 111606. PMID 34555600 DOI: 10.1016/j.jinorgbio.2021.111606   
2021 Lin ZY, Yun QZ, Wu L, Zhang TW, Yao TZ. Pharmacological basis and new insights of deguelin concerning its anticancer effects. Pharmacological Research. 105935. PMID 34644595 DOI: 10.1016/j.phrs.2021.105935   
2021 Liu Q, Zhai L, Han M, Shi D, Sun Z, Peng S, Wang M, Zhang C, Gao J, Yan W, Jiang Q, Chen D, Xu Q, Tan M, Sun Y. SHP2 inhibition attenuates osteoarthritis by maintaining homeostasis of cartilage metabolism via the DOK1/UPP1/uridine cascade. Arthritis & Rheumatology (Hoboken, N.J.). PMID 34569725 DOI: 10.1002/art.41988   
2021 Huang LC, Taujale R, Gravel N, Venkat A, Yeung W, Byrne DP, Eyers PA, Kannan N. KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases. Bmc Bioinformatics. 22: 446. PMID 34537014 DOI: 10.1186/s12859-021-04358-3   
2021 Lisa MN, Sogues A, Barilone N, Baumgart M, Gil M, Graña M, Durán R, Biondi RM, Bellinzoni M, Bott M, Alzari PM. A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG. Mbio. e0171721. PMID 34607462 DOI: 10.1128/mBio.01717-21   
2021 Wang W, Mevellec L, Liu A, Struble G, Miller R, Allen SJ, Federowicz K, Wroblowski B, Vialard J, Ahn K, Krosky D. Discovery of an Allosteric, Inactive Conformation-Selective Inhibitor of Full-Length HPK1 Utilizing a Kinase Cascade Assay. Biochemistry. PMID 34608799 DOI: 10.1021/acs.biochem.1c00486   
2021 Wang J, Peng H, Timur AA, Pasupuleti V, Yao Y, Zhang T, You SA, Fan C, Yu Y, Jia X, Chen J, Xu C, Chen Q, Wang Q. Receptor and Molecular Mechanism of AGGF1 Signaling in Endothelial Cell Functions and Angiogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA121316867. PMID 34551592 DOI: 10.1161/ATVBAHA.121.316867   
2021 Ozkan AD, Gettas T, Sogata A, Phaychanpheng W, Zhou M, Lacroix JJ. Mechanical and chemical activation of GPR68 probed with a genetically encoded fluorescent reporter. Journal of Cell Science. 134. PMID 34322699 DOI: 10.1242/jcs.255455   
2021 Kong L, Zhang Q, Mao J, Cheng L, Shi X, Yu L, Hu J, Yang M, Li L, Liu B, Qian X. A dual-targeted molecular therapy of PP242 and cetuximab plays an anti-tumor effect through EGFR downstream signaling pathways in colorectal cancer. Journal of Gastrointestinal Oncology. 12: 1625-1642. PMID 34532116 DOI: 10.21037/jgo-21-467   
2021 Qin L, Cao X, Kaneko T, Voss C, Liu X, Wang G, Li SS. Dynamic interplay of two molecular switches enabled by the MEK1/2-ERK1/2 and IL-6-STAT3 signaling axes controls epithelial cell migration in response to growth factors. The Journal of Biological Chemistry. 101161. PMID 34480897 DOI: 10.1016/j.jbc.2021.101161   
2021 Quambusch L, Depta L, Landel I, Lubeck M, Kirschner T, Nabert J, Uhlenbrock N, Weisner J, Kostka M, Levy LM, Schultz-Fademrecht C, Glanemann F, Althoff K, Müller MP, Siveke JT, et al. Cellular model system to dissect the isoform-selectivity of Akt inhibitors. Nature Communications. 12: 5297. PMID 34489430 DOI: 10.1038/s41467-021-25512-8   
2021 Liang LY, Roy M, Horne C, Sandow JJ, Surudoi M, Dagley LF, Young SN, Dite T, Babon JJ, Janes PW, Patel O, Murphy JM, Lucet IS. The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signaling hubs. The Biochemical Journal. PMID 34431498 DOI: 10.1042/BCJ20210572   
2021 Drysch M, Schmidt SV, Becerikli M, Reinkemeier F, Dittfeld S, Wagner JM, Dadras M, Sogorski A, von Glinski M, Lehnhardt M, Behr B, Wallner C. Myostatin Deficiency Protects C2C12 Cells from Oxidative Stress by Inhibiting Intrinsic Activation of Apoptosis. Cells. 10. PMID 34359850 DOI: 10.3390/cells10071680   
2021 Wang C, Ruan L, Shi H, Lin W, Liu L, Li S. Phosphorylation of Shrimp Tcf by a Viral Protein Kinase WSV083 Suppresses Its Antiviral Effect. Frontiers in Immunology. 12: 698697. PMID 34408747 DOI: 10.3389/fimmu.2021.698697   
2021 Shams R, Ito Y, Miyatake H. Evaluation of the Binding Kinetics of RHEB with mTORC1 by In-Cell and In Vitro Assays. International Journal of Molecular Sciences. 22. PMID 34445471 DOI: 10.3390/ijms22168766   
2021 Hollenstein DM, Gérecová G, Romanov N, Ferrari J, Veis J, Janschitz M, Beyer R, Schüller C, Ogris E, Hartl M, Ammerer G, Reiter W. A phosphatase-centric mechanism drives stress signaling response. Embo Reports. e52476. PMID 34558777 DOI: 10.15252/embr.202152476   
2021 Dong Y, Han H, Li Y, Guo L. [Roles of Histidine Kinases and Histidine Phosphatases in Cancer]. Zhongguo Fei Ai Za Zhi = Chinese Journal of Lung Cancer. PMID 34455734 DOI: 10.3779/j.issn.1009-3419.2021.102.28   
2021 Ortega MA, Fraile-Martínez O, García-Montero C, Ruiz-Grande F, Barrena S, Montoya H, Pekarek L, Zoullas S, Alvarez-Mon MA, Sainz F, Asúnsolo A, Acero J, Álvarez-Mon M, Buján J, García-Honduvilla N, et al. Chronic venous disease patients show increased IRS-4 expression in the great saphenous vein wall. The Journal of International Medical Research. 49: 3000605211041275. PMID 34590920 DOI: 10.1177/03000605211041275   
2021 Schastnaya E, Raguz Nakic Z, Gruber CH, Doubleday PF, Krishnan A, Johns NI, Park J, Wang HH, Sauer U. Extensive regulation of enzyme activity by phosphorylation in Escherichia coli. Nature Communications. 12: 5650. PMID 34561442 DOI: 10.1038/s41467-021-25988-4   
2021 Bender KW, Couto D, Kadota Y, Macho AP, Sklenar J, Derbyshire P, Bjornson M, DeFalco TA, Petriello A, Font Farre M, Schwessinger B, Ntoukakis V, Stransfeld L, Jones AME, Menke FLH, et al. Activation loop phosphorylaton of a non-RD receptor kinase initiates plant innate immune signaling. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34531323 DOI: 10.1073/pnas.2108242118   
2021 Karia P, Yoshioka K, Moeder W. Multiple phosphorylation events of the mitochondrial membrane protein TTM1 regulate cell death during senescence. The Plant Journal : For Cell and Molecular Biology. PMID 34409658 DOI: 10.1111/tpj.15470   
2021 Ballard DJ, Peng HY, Das JK, Kumar A, Wang L, Ren Y, Xiong X, Ren X, Yang JM, Song J. Insights Into the Pathologic Roles and Regulation of Eukaryotic Elongation Factor-2 Kinase. Frontiers in Molecular Biosciences. 8: 727863. PMID 34532346 DOI: 10.3389/fmolb.2021.727863