Nick Westwood - Publications

Affiliations: 
Chemistry University of St. Andrews, Saint Andrews, Scotland, United Kingdom 

86 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Chen ASY, Westwood NJ, Brear P, Rogers GW, Mavridis L, Mitchell JBO. A Random Forest Model for Predicting Allosteric and Functional Sites on Proteins Molecular Informatics. DOI: 10.1002/minf.201500108  0.72
2015 Healy AR, Izumikawa M, Slawin AM, Shin-Ya K, Westwood NJ. Stereochemical Assignment of the Protein-Protein Interaction Inhibitor JBIR-22 by Total Synthesis. Angewandte Chemie (Weinheim An Der Bergstrasse, Germany). 127: 4118-4122. PMID 27087707 DOI: 10.1002/ange.201411141  0.72
2015 Oueis E, Mann G, Ludwig H, Adamson C, Redpath P, Migaud M, Westwood N, Naismith JH. Derivatisable cyanobactin analogues: a semi-synthetic approach. Chembiochem : a European Journal of Chemical Biology. PMID 26507241 DOI: 10.1002/cbic.201500494  0.72
2015 Healy AR, Westwood NJ. Synthetic studies on the bioactive tetramic acid JBIR-22 using a late stage Diels-Alder reaction. Organic & Biomolecular Chemistry. 13: 10527-31. PMID 26337398 DOI: 10.1039/c5ob01771h  0.72
2015 Figuera-Losada M, Stathis M, Dorskind JM, Thomas AG, Bandaru VV, Yoo SW, Westwood NJ, Rogers GW, McArthur JC, Haughey NJ, Slusher BS, Rojas C. Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties. Plos One. 10: e0124481. PMID 26010541 DOI: 10.1371/journal.pone.0124481  0.72
2015 Deuss PJ, Scott M, Tran F, Westwood NJ, de Vries JG, Barta K. Aromatic Monomers by in Situ Conversion of Reactive Intermediates in the Acid-Catalyzed Depolymerization of Lignin. Journal of the American Chemical Society. 137: 7456-67. PMID 26001165 DOI: 10.1021/jacs.5b03693  0.72
2015 Lancefield CS, Slawin AM, Westwood NJ, Lebl T. The use of residual dipolar coupling for conformational analysis of structurally related natural products. Magnetic Resonance in Chemistry : Mrc. 53: 467-75. PMID 25854705 DOI: 10.1002/mrc.4213  0.72
2015 Schölz C, Weinert BT, Wagner SA, Beli P, Miyake Y, Qi J, Jensen LJ, Streicher W, McCarthy AR, Westwood NJ, Lain S, Cox J, Matthias P, Mann M, Bradner JE, et al. Acetylation site specificities of lysine deacetylase inhibitors in human cells. Nature Biotechnology. 33: 415-23. PMID 25751058 DOI: 10.1038/nbt.3130  0.72
2015 Healy AR, Izumikawa M, Slawin AM, Shin-Ya K, Westwood NJ. Stereochemical assignment of the protein-protein interaction inhibitor JBIR-22 by total synthesis. Angewandte Chemie (International Ed. in English). 54: 4046-50. PMID 25650886 DOI: 10.1002/anie.201411141  0.72
2015 Healy AR, Vinale F, Lorito M, Westwood NJ. Total synthesis and biological evaluation of the tetramic acid based natural product harzianic acid and its stereoisomers. Organic Letters. 17: 692-5. PMID 25629709 DOI: 10.1021/ol503717r  0.72
2015 Lancefield CS, Ojo OS, Tran F, Westwood NJ. Isolation of functionalized phenolic monomers through selective oxidation and C-O bond cleavage of the β-O-4 linkages in lignin. Angewandte Chemie (International Ed. in English). 54: 258-62. PMID 25377996 DOI: 10.1002/anie.201409408  0.72
2015 Odell AV, Tran F, Foderaro JE, Poupart S, Pathak R, Westwood NJ, Ward GE. Yeast three-hybrid screen identifies TgBRADIN/GRA24 as a negative regulator of toxoplasma gondii bradyzoite differentiation Plos One. 10. DOI: 10.1371/journal.pone.0120331  0.72
2015 Lancefield CS, Westwood NJ. The synthesis and analysis of advanced lignin model polymers Green Chemistry. 17: 4980-4990. DOI: 10.1039/c5gc01334h  0.72
2015 Healy AR, Houston DR, Remnant L, Huart AS, Brychtova V, Maslon MM, Meers O, Muller P, Krejci A, Blackburn EA, Vojtesek B, Hernychova L, Walkinshaw MD, Westwood NJ, Hupp TR. Discovery of a novel ligand that modulates the protein-protein interactions of the AAA+ superfamily oncoprotein reptin Chemical Science. 6: 3109-3116. DOI: 10.1039/c4sc03885a  0.72
2015 Bouxin FP, McVeigh A, Tran F, Westwood NJ, Jarvis MC, Jackson SD. Catalytic depolymerisation of isolated lignins to fine chemicals using a Pt/alumina catalyst: Part 1 - Impact of the lignin structure Green Chemistry. 17: 1235-1242. DOI: 10.1039/c4gc01678e  0.72
2014 Sidik SM, Hackett CG, Tran F, Westwood NJ, Lourido S. Efficient genome engineering of Toxoplasma gondii using CRISPR/Cas9. Plos One. 9: e100450. PMID 24971596 DOI: 10.1371/journal.pone.0100450  0.72
2014 Leung JM, Tran F, Pathak RB, Poupart S, Heaslip AT, Ballif BA, Westwood NJ, Ward GE. Identification of T. gondii myosin light chain-1 as a direct target of TachypleginA-2, a small-molecule inhibitor of parasite motility and invasion. Plos One. 9: e98056. PMID 24892871 DOI: 10.1371/journal.pone.0098056  0.72
2014 Tilley LD, Krishnamurthy S, Westwood NJ, Ward GE. Identification of TgCBAP, a novel cytoskeletal protein that localizes to three distinct subcompartments of the Toxoplasma gondii pellicle. Plos One. 9: e98492. PMID 24887026 DOI: 10.1371/journal.pone.0098492  0.72
2014 Müller I, Larsson K, Frenzel A, Oliynyk G, Zirath H, Prochownik EV, Westwood NJ, Henriksson MA. Targeting of the MYCN protein with small molecule c-MYC inhibitors. Plos One. 9: e97285. PMID 24859015 DOI: 10.1371/journal.pone.0097285  0.72
2014 Liu G, Lancefield CS, Lorion MM, Slawin AMZ, Westwood NJ. Synthesis and oxidative cleavage of oxazinocarbazoles: Atropselective access to medium-sized rings Synthesis (Germany). 46: 2808-2814. DOI: 10.1055/s-0034-1378530  0.72
2013 Groves MJ, Johnson CE, James J, Prescott AR, Cunningham J, Haydock S, Pepper C, Fegan C, Pirrie L, Westwood NJ, Coates PJ, Ganley IG, Tauro S. p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia. British Journal of Cancer. 109: 2434-44. PMID 24091621 DOI: 10.1038/bjc.2013.601  0.72
2013 Tran F, Odell AV, Ward GE, Westwood NJ. A modular approach to triazole-containing chemical inducers of dimerisation for yeast three-hybrid screening. Molecules (Basel, Switzerland). 18: 11639-57. PMID 24064457 DOI: 10.3390/molecules180911639  0.72
2013 MacCallum SF, Groves MJ, James J, Murray K, Appleyard V, Prescott AR, Drbal AA, Nicolaou A, Cunningham J, Haydock S, Ganley IG, Westwood NJ, Coates PJ, Lain S, Tauro S. Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6. Scientific Reports. 3: 1275. PMID 23429453 DOI: 10.1038/srep01275  0.72
2013 McCarthy AR, Sachweh MC, Higgins M, Campbell J, Drummond CJ, van Leeuwen IM, Pirrie L, Ladds MJ, Westwood NJ, Laín S. Tenovin-D3, a novel small-molecule inhibitor of sirtuin SirT2, increases p21 (CDKN1A) expression in a p53-independent manner. Molecular Cancer Therapeutics. 12: 352-60. PMID 23322738 DOI: 10.1158/1535-7163.MCT-12-0900  0.72
2013 Zhou L, Stewart G, Rideau E, Westwood NJ, Smith TK. A class of 5-nitro-2-furancarboxylamides with potent trypanocidal activity against Trypanosoma brucei in vitro. Journal of Medicinal Chemistry. 56: 796-806. PMID 23281892 DOI: 10.1021/jm301215e  0.72
2013 Alphey MS, Pirrie L, Torrie LS, Boulkeroua WA, Gardiner M, Sarkar A, Maringer M, Oehlmann W, Brenk R, Scherman MS, McNeil M, Rejzek M, Field RA, Singh M, Gray D, ... Westwood NJ, et al. Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa. Acs Chemical Biology. 8: 387-96. PMID 23138692 DOI: 10.1021/cb300426u  0.72
2012 Lancefield CS, Zhou L, Lébl T, Slawin AM, Westwood NJ. The synthesis of melohenine B and a related natural product. Organic Letters. 14: 6166-9. PMID 23214465 DOI: 10.1021/ol302859j  0.72
2012 Pirrie L, McCarthy AR, Major LL, Morkūnaitė V, Zubrienė A, Matulis D, Lain S, Lebl T, Westwood NJ. Discovery and validation of SIRT2 inhibitors based on tenovin-6: use of a ¹H-NMR method to assess deacetylase activity. Molecules (Basel, Switzerland). 17: 12206-24. PMID 23079492 DOI: 10.3390/molecules171012206  0.72
2012 Brear P, Telford J, Taylor GL, Westwood NJ. Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem : a European Journal of Chemical Biology. 13: 2374-83. PMID 23070966 DOI: 10.1002/cbic.201200433  0.72
2012 Zhou L, Ishizaki H, Spitzer M, Taylor KL, Temperley ND, Johnson SL, Brear P, Gautier P, Zeng Z, Mitchell A, Narayan V, McNeil EM, Melton DW, Smith TK, Tyers M, ... Westwood NJ, et al. ALDH2 mediates 5-nitrofuran activity in multiple species. Chemistry & Biology. 19: 883-92. PMID 22840776 DOI: 10.1016/j.chembiol.2012.05.017  0.72
2012 McCarthy AR, Pirrie L, Hollick JJ, Ronseaux S, Campbell J, Higgins M, Staples OD, Tran F, Slawin AM, Lain S, Westwood NJ. Synthesis and biological characterisation of sirtuin inhibitors based on the tenovins. Bioorganic & Medicinal Chemistry. 20: 1779-93. PMID 22304848 DOI: 10.1016/j.bmc.2012.01.001  0.72
2011 van Leeuwen IM, Higgins M, Campbell J, Brown CJ, McCarthy AR, Pirrie L, Westwood NJ, Laín S. Mechanism-specific signatures for small-molecule p53 activators. Cell Cycle (Georgetown, Tex.). 10: 1590-8. PMID 21490429 DOI: 10.4161/cc.10.10.15519  0.72
2011 Jones AM, Liu G, Lorion MM, Patterson S, Lebl T, Slawin AM, Westwood NJ. Asymmetric catalytic oxidative cleavage of polycyclic systems: the synthesis of atropisomeric diazonanes and diazecanes. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 5714-8. PMID 21469229 DOI: 10.1002/chem.201003188  0.72
2011 Walton JG, Jones DC, Kiuru P, Durie AJ, Westwood NJ, Fairlamb AH. Synthesis and evaluation of indatraline-based inhibitors for trypanothione reductase. Chemmedchem. 6: 321-8. PMID 21275055 DOI: 10.1002/cmdc.201000442  0.72
2011 Lawson CP, Slawin AM, Westwood NJ. Application of the copper catalysed N-arylation of amidines in the synthesis of analogues of the chemical tool, blebbistatin. Chemical Communications (Cambridge, England). 47: 1057-9. PMID 21079840 DOI: 10.1039/c0cc03624b  0.72
2011 Medda F, Joseph TL, Pirrie L, Higgins M, Slawin AMZ, Lain S, Verma C, Westwood NJ. N1-Benzyl substituted cambinol analogues as isozyme selective inhibitors of the sirtuin family of protein deacetylases Medchemcomm. 2: 611-615. DOI: 10.1039/c1md00023c  0.72
2010 McCarthy AR, Hollick JJ, Westwood NJ. The discovery of nongenotoxic activators of p53: building on a cell-based high-throughput screen. Seminars in Cancer Biology. 20: 40-5. PMID 20206696 DOI: 10.1016/j.semcancer.2010.02.007  0.72
2010 McIntyre NA, McInnes C, Griffiths G, Barnett AL, Kontopidis G, Slawin AM, Jackson W, Thomas M, Zheleva DI, Wang S, Blake DG, Westwood NJ, Fischer PM. Design, synthesis, and evaluation of 2-methyl- and 2-amino-N-aryl-4,5-dihydrothiazolo[4,5-h]quinazolin-8-amines as ring-constrained 2-anilino-4-(thiazol-5-yl)pyrimidine cyclin-dependent kinase inhibitors. Journal of Medicinal Chemistry. 53: 2136-45. PMID 20146435 DOI: 10.1021/jm901660c  0.72
2010 Heaslip AT, Leung JM, Carey KL, Catti F, Warshaw DM, Westwood NJ, Ballif BA, Ward GE. A small-molecule inhibitor of T. gondii motility induces the posttranslational modification of myosin light chain-1 and inhibits myosin motor activity. Plos Pathogens. 6: e1000720. PMID 20084115 DOI: 10.1371/journal.ppat.1000720  0.72
2010 Voûte N, Philp D, Slawin AM, Westwood NJ. Studies on the Claisen rearrangements in the indolo[2,3-b]quinoline system. Organic & Biomolecular Chemistry. 8: 442-50. PMID 20066282 DOI: 10.1039/b915677a  0.72
2010 Liu G, Botting CH, Evans KM, Walton JA, Xu G, Slawin AM, Westwood NJ. Optimisation of conoidin A, a peroxiredoxin inhibitor. Chemmedchem. 5: 41-5. PMID 19946931 DOI: 10.1002/cmdc.200900391  0.72
2010 Jones AM, Lorion MM, Lebl T, Slawin AMZ, Philp D, Westwood NJ. The chemical reactivity of a known anti-psoriasis drug. Part 1: Further insights into the products resulting from oxidative cleavage Tetrahedron. 66: 9667-9674. DOI: 10.1016/j.tet.2010.10.044  0.72
2010 Lebl T, Lorion MM, Jones AM, Philp D, Westwood NJ. Synthesis and characterisation of medium-sized ring systems by oxidative cleavage. Part 2: Insights from the study of ring expanded analogues Tetrahedron. 66: 9694-9702. DOI: 10.1016/j.tet.2010.10.043  0.72
2009 Makiyi EF, Frade RF, Lebl T, Jaffray EG, Cobb SE, Harvey AL, Slawin AM, Hay RT, Westwood NJ. Iso-seco-tanapartholides: Isolation, Synthesis and Biological Evaluation. European Journal of Organic Chemistry. 2009: 5711-5715. PMID 23606807 DOI: 10.1002/ejoc.200901016  0.72
2009 Haraldsen JD, Liu G, Botting CH, Walton JG, Storm J, Phalen TJ, Kwok LY, Soldati-Favre D, Heintz NH, Müller S, Westwood NJ, Ward GE. IDENTIFICATION OF CONOIDIN A AS A COVALENT INHIBITOR OF PEROXIREDOXIN II. Organic & Biomolecular Chemistry. 7: 3040-3048. PMID 21359112 DOI: 10.1039/B901735F  0.72
2009 Jahan N, Potter JA, Sheikh MA, Botting CH, Shirran SL, Westwood NJ, Taylor GL. Insights into the biosynthesis of the Vibrio cholerae major autoinducer CAI-1 from the crystal structure of the PLP-dependent enzyme CqsA. Journal of Molecular Biology. 392: 763-73. PMID 19631226 DOI: 10.1016/j.jmb.2009.07.042  0.72
2009 Medda F, Russell RJ, Higgins M, McCarthy AR, Campbell J, Slawin AM, Lane DP, Lain S, Westwood NJ. Novel cambinol analogs as sirtuin inhibitors: synthesis, biological evaluation, and rationalization of activity. Journal of Medicinal Chemistry. 52: 2673-82. PMID 19419202 DOI: 10.1021/jm8014298  0.72
2009 Walton JGA, Patterson S, Liu G, Haraldsen JD, Hollick JJ, Slawin AMZ, Ward GE, Westwood NJ. Synthesis and biological evaluation of functionalised tetrahydro-β- carboline analogues as inhibitors of Toxoplasma gondii invasion Organic and Biomolecular Chemistry. 7: 3049-3060. DOI: 10.1039/b902319d  0.72
2009 Jones AM, Lebl T, Patterson S, van Mourik T, Früchtl HA, Philp D, Slawin AMZ, Westwood NJ. Parallel synthesis and spectroscopic analysis of a collection of heterocycles based on the diazabenz[e]aceanthrylene core structure Tetrahedron. 65: 563-578. DOI: 10.1016/j.tet.2008.10.049  0.72
2008 Catti F, Kiuru PS, Slawin AM, Westwood NJ. The synthesis of highly functionalised pyridines using Ghosez-type reactions of dihydropyrazoles. Tetrahedron. 64: 9561-9566. PMID 19794812 DOI: 10.1016/j.tet.2008.07.063  0.72
2008 Staples OD, Hollick JJ, Campbell J, Higgins M, McCarthy AR, Appleyard V, Murray KE, Baker L, Thompson A, Ronseaux S, Slawin AM, Lane DP, Westwood NJ, Lain S. Characterization, chemical optimization and anti-tumour activity of a tubulin poison identified by a p53-based phenotypic screen. Cell Cycle (Georgetown, Tex.). 7: 3417-27. PMID 18971638  0.72
2008 Lucas-Lopez C, Allingham JS, Lebl T, Lawson CP, Brenk R, Sellers JR, Rayment I, Westwood NJ. The small molecule tool (S)-(-)-blebbistatin: novel insights of relevance to myosin inhibitor design. Organic & Biomolecular Chemistry. 6: 2076-84. PMID 18528569 DOI: 10.1039/b801223g  0.72
2008 Lain S, Hollick JJ, Campbell J, Staples OD, Higgins M, Aoubala M, McCarthy A, Appleyard V, Murray KE, Baker L, Thompson A, Mathers J, Holland SJ, Stark MJ, Pass G, ... ... Westwood NJ, et al. Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell. 13: 454-63. PMID 18455128 DOI: 10.1016/j.ccr.2008.03.004  0.72
2007 Evans KM, Haraldsen JD, Pearson RJ, Slawin AM, Ward GE, Westwood NJ. Synthesis and chemical characterisation of target identification reagents based on an inhibitor of human cell invasion by the parasite Toxoplasma gondii. Organic & Biomolecular Chemistry. 5: 2063-9. PMID 17581649 DOI: 10.1039/b704685e  0.72
2007 Evans KM, Slawin AM, Lebl T, Philp D, Westwood NJ. An improved understanding of the reaction of bis(bromomethyl)quinoxaline 1-N-oxides with amines using substituent effects. The Journal of Organic Chemistry. 72: 3186-93. PMID 17407354 DOI: 10.1021/jo062380y  0.72
2007 Morgan RE, Evans KM, Patterson S, Catti F, Ward GE, Westwood NJ. Targeting invasion and egress: from tools to drugs? Current Drug Targets. 8: 61-74. PMID 17266531 DOI: 10.2174/138945007779315678  0.72
2005 Pearson RJ, Evans KM, Slawin AM, Philp D, Westwood NJ. Controlling the outcome of an N-alkylation reaction by using N-oxide functional groups. The Journal of Organic Chemistry. 70: 5055-61. PMID 15960505 DOI: 10.1021/jo0503106  0.72
2005 Berkson RG, Hollick JJ, Westwood NJ, Woods JA, Lane DP, Lain S. Pilot screening programme for small molecule activators of p53. International Journal of Cancer. Journal International Du Cancer. 115: 701-10. PMID 15729694 DOI: 10.1002/ijc.20968  0.72
2005 Riggs RL, Morton CJH, Slawin AMZ, Smith DM, Westwood NJ, Austen WSD, Stuart KE. Synthetic studies related to diketopyrrolopyrrole (DPP) pigments. Part 3: Syntheses of tri- and tetra-aryl DPPs Tetrahedron. 61: 11230-11243. DOI: 10.1016/j.tet.2005.09.005  0.72
2005 Morton CJH, Riggs RL, Smith DM, Westwood NJ, Lightfoot P, Slawin AMZ. Synthetic studies related to diketopyrrolopyrrole (DPP) pigments. Part 2: The use of esters in place of nitriles in standard DPP syntheses: Claisen-type acylations and furopyrrole intermediates Tetrahedron. 61: 727-738. DOI: 10.1016/j.tet.2004.10.027  0.72
2005 Lucas-Lopez C, Patterson S, Blum T, Straight AF, Toth J, Slawin AMZ, Mitchison TJ, Sellers JR, Westwood NJ. Absolute stereochemical assignment and fluorescence tuning of the small molecule tool, (-)-blebbistatin European Journal of Organic Chemistry. 1736-1740. DOI: 10.1002/ejoc.200500103  0.72
2004 Morgan RE, Westwood NJ. Screening and synthesis: high throughput technologies applied to parasitology. Parasitology. 128: S71-9. PMID 16454900 DOI: 10.1017/S0031182004007073  0.72
2004 Westwood NJ. Chemical genetics: how does it function? Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 362: 2761-74. PMID 15539369 DOI: 10.1098/rsta.2004.1467  0.72
2004 Yarrow JC, Perlman ZE, Westwood NJ, Mitchison TJ. A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods. Bmc Biotechnology. 4: 21. PMID 15357872 DOI: 10.1186/1472-6750-4-21  0.72
2004 Carey KL, Westwood NJ, Mitchison TJ, Ward GE. A small-molecule approach to studying invasive mechanisms of Toxoplasma gondii. Proceedings of the National Academy of Sciences of the United States of America. 101: 7433-8. PMID 15123807 DOI: 10.1073/pnas.0307769101  0.72
2004 Patterson S, Lorenz C, Slawin AMZ, Westwood NJ. Rapid access to a pentacyclic library core structure: A microwave assisted approach Qsar and Combinatorial Science. 23: 883-890. DOI: 10.1002/qsar.200420047  0.72
2003 Straight AF, Cheung A, Limouze J, Chen I, Westwood NJ, Sellers JR, Mitchison TJ. Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. Science (New York, N.Y.). 299: 1743-7. PMID 12637748 DOI: 10.1126/science.1081412  0.72
2002 Ward GE, Carey KL, Westwood NJ. Using small molecules to study big questions in cellular microbiology. Cellular Microbiology. 4: 471-82. PMID 12174082 DOI: 10.1046/j.1462-5822.2002.00205.x  0.72
2001 Pelish HE, Westwood NJ, Feng Y, Kirchhausen T, Shair MD. Use of biomimetic diversity-oriented synthesis to discover galanthamine-like molecules with biological properties beyond those of the natural product. Journal of the American Chemical Society. 123: 6740-1. PMID 11439080 DOI: 10.1021/ja016093h  0.72
2001 Tallarico JA, Depew KM, Pelish HE, Westwood NJ, Lindsley CW, Shair MD, Schreiber SL, Foley MA. An alkylsilyl-tethered, high-capacity solid support amenable to diversity-oriented synthesis for one-bead, one-stock solution chemical genetics. Journal of Combinatorial Chemistry. 3: 312-8. PMID 11350255 DOI: 10.1021/cc000107i  0.72
1999 Wilmouth RC, Kassamally S, Westwood NJ, Sheppard RJ, Claridge TD, Aplin RT, Wright PA, Pritchard GJ, Schofield CJ. Mechanistic insights into the inhibition of serine proteases by monocyclic lactams. Biochemistry. 38: 7989-98. PMID 10387042 DOI: 10.1021/bi990098y  0.72
1999 Magnus P, Westwood N. Ireland-Claisen rearrangement for the stereoselective formation of the C2-C3 bond in taxanes Tetrahedron Letters. 40: 4659-4662. DOI: 10.1016/S0040-4039(99)00828-X  0.72
1999 Magnus P, Westwood N, Spyvee M, Frost C, Linnane P, Tavares F, Lynch V. Taxane diterpenes 5: Synthesis of the A- and C-rings: An unusual rearrangement of an N-hydroxyimino lactone Tetrahedron. 55: 6435-6452. DOI: 10.1016/S0040-4020(99)00305-1  0.72
1998 Wilmouth RC, Westwood NJ, Anderson K, Brownlee W, Claridge TD, Clifton IJ, Pritchard GJ, Aplin RT, Schofield CJ. Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex. Biochemistry. 37: 17506-13. PMID 9860865 DOI: 10.1021/bi9816249  0.68
1998 Magnus P, Ujjainwalla F, Westwood N, Lynch V. Taxane diterpenes 4: Autoxidation, epimerization and isomerization for the introduction of functionality into the taxane ABC ring system Tetrahedron. 54: 3069-3092. DOI: 10.1016/S0040-4020(98)00056-8  0.72
1997 Eid CN, Halligan NG, Nicas TI, Mullen DL, Butler TF, Loncharich RJ, Paschal JW, Schofield CJ, Westwood NJ, Cheng L. Tripeptide LY301621 and its diastereomers as methicillin potentiators against methicillin resistant Staphylococcus aureus The Journal of Antibiotics. 50: 283-5. PMID 9439706  0.68
1997 Wilmouth RC, Clifton IJ, Robinson CV, Roach PL, Aplin RT, Westwood NJ, Hajdu J, Schofield CJ. Structure of a specific acyl-enzyme complex formed between beta-casomorphin-7 and porcine pancreatic elastase. Nature Structural Biology. 4: 456-62. PMID 9187653 DOI: 10.1038/nsb0697-456  0.72
1997 Eid CN, Halligan NG, Nicas TI, Mullen DL, Butler TF, Loncharich RJ, Paschal JW, Schofield CJ, Westwood NJ, Cheng L. Tripeptide LY301621 and its diastereomers as methicillin potentiators against methicillin resistant Staphylococcus aureus. The Journal of Antibiotics. 50: 283-5. PMID 9127206  0.72
1997 Magnus P, Tavares F, Westwood N. Enantioselective synthesis of a taxane C-ring component using the Schultz asymmetric Birch reduction methodology Tetrahedron Letters. 38: 1341-1344. DOI: 10.1016/S0040-4039(97)00094-4  0.72
1997 Westwood NJ, Claridge TDW, Edwards PN, Schofield CJ. Reversible acylation of elastase by γ-lactam analogues of β-lactam inhibitors Bioorganic and Medicinal Chemistry Letters. 7: 2973-2978.  0.72
1997 Westwood NJ, Schofield CJ, Claridge TDW. Studies on the reactivity of azetidin-2-ones in phosphate buffer Journal of the Chemical Society - Perkin Transactions 1. 2725-2729.  0.72
1997 Adlington RM, Baldwin JE, McCoull W, Pritchard GJ, Schofield CJ, Westwood NJ. An investigation of the N-arylsulfonylation of 2-azetidinones Synthetic Communications. 27: 3803-3813.  0.72
1996 Magnus P, Ujjainwalla F, Westwood N, Lynch V. Isomerization, autooxidation and epimerization for the introduction of C-1 to C-5 functionality into the taxane ABC ring system Tetrahedron Letters. 37: 6639-6642. DOI: 10.1016/S0040-4039(96)01495-5  0.72
1994 Aplin RT, Robinson CV, Schofield CJ, Westwood NJ. Does the observation of noncovalent complexes between biomolecules by electrospray ionisation mass spectrometry necessarily reflect specific solution interactions? Journal of the Chemical Society, Chemical Communications. 2415-2417. DOI: 10.1039/C39940002415  0.72
1993 Aplin RT, Robinson CV, Schofield CJ, Westwood NJ. An investigation into the mechanism of elastase inhibition by cephalosporins using electrospray ionisation mass spectrometry Tetrahedron. 49: 10903-10912. DOI: 10.1016/S0040-4020(01)80243-X  0.72
1992 Aplin RT, Robinson CV, Schofield CJ, Westwood NJ. Studies on the inhibition of porcine pancreatic elastase using electrospray mass spectrometry Journal of the Chemical Society, Chemical Communications. 1650-1652. DOI: 10.1039/C39920001650  0.72
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