Nick Westwood - Publications

Affiliations: 
Chemistry University of St. Andrews, Saint Andrews, Scotland, United Kingdom 

21/211 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Coufalova D, Remnant L, Hernychova L, Muller P, Healy A, Kannan S, Vojtesek B, Westwood N, Verma CS, Vojtesek B, Hupp TR, Houston DR. An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin. Journal of Proteomics. PMID 30862565 DOI: 10.1016/J.Jprot.2019.02.012  0.537
2015 Healy AR, Izumikawa M, Slawin AM, Shin-Ya K, Westwood NJ. Stereochemical Assignment of the Protein-Protein Interaction Inhibitor JBIR-22 by Total Synthesis. Angewandte Chemie (Weinheim An Der Bergstrasse, Germany). 127: 4118-4122. PMID 27087707 DOI: 10.1002/ange.201411141  0.574
2015 Healy AR, Westwood NJ. Synthetic studies on the bioactive tetramic acid JBIR-22 using a late stage Diels-Alder reaction. Organic & Biomolecular Chemistry. 13: 10527-31. PMID 26337398 DOI: 10.1039/c5ob01771h  0.514
2015 Healy AR, Izumikawa M, Slawin AM, Shin-Ya K, Westwood NJ. Stereochemical assignment of the protein-protein interaction inhibitor JBIR-22 by total synthesis. Angewandte Chemie (International Ed. in English). 54: 4046-50. PMID 25650886 DOI: 10.1002/Anie.201411141  0.574
2015 Healy AR, Vinale F, Lorito M, Westwood NJ. Total synthesis and biological evaluation of the tetramic acid based natural product harzianic acid and its stereoisomers. Organic Letters. 17: 692-5. PMID 25629709 DOI: 10.1021/ol503717r  0.544
2015 Healy AR, Houston DR, Remnant L, Huart AS, Brychtova V, Maslon MM, Meers O, Muller P, Krejci A, Blackburn EA, Vojtesek B, Hernychova L, Walkinshaw MD, Westwood NJ, Hupp TR. Discovery of a novel ligand that modulates the protein-protein interactions of the AAA+ superfamily oncoprotein reptin Chemical Science. 6: 3109-3116. DOI: 10.1039/c4sc03885a  0.482
2010 WESTWOOD NJ, SCHOFIELD CJ, CLARIDGE TDW. ChemInform Abstract: Studies on the Reactivity of Azetidin-2-ones in Phosphate Buffer. Cheminform. 29: no-no. DOI: 10.1002/chin.199802245  0.317
2010 ADLINGTON RM, BALDWIN JE, MCCOULL W, PRITCHARD GJ, SCHOFIELD CJ, WESTWOOD NJ. ChemInform Abstract: An Investigation of the N-Arylsulfonylation of 2-Azetidinones. Cheminform. 28: no-no. DOI: 10.1002/chin.199752129  0.409
2001 Pelish HE, Westwood NJ, Feng Y, Kirchhausen T, Shair MD. Use of biomimetic diversity-oriented synthesis to discover galanthamine-like molecules with biological properties beyond those of the natural product. Journal of the American Chemical Society. 123: 6740-1. PMID 11439080 DOI: 10.1021/Ja016093H  0.683
2001 Tallarico JA, Depew KM, Pelish HE, Westwood NJ, Lindsley CW, Shair MD, Schreiber SL, Foley MA. An alkylsilyl-tethered, high-capacity solid support amenable to diversity-oriented synthesis for one-bead, one-stock solution chemical genetics. Journal of Combinatorial Chemistry. 3: 312-8. PMID 11350255 DOI: 10.1021/Cc000107I  0.646
1999 Wilmouth RC, Kassamally S, Westwood NJ, Sheppard RJ, Claridge TD, Aplin RT, Wright PA, Pritchard GJ, Schofield CJ. Mechanistic insights into the inhibition of serine proteases by monocyclic lactams. Biochemistry. 38: 7989-98. PMID 10387042 DOI: 10.1021/Bi990098Y  0.418
1999 Magnus P, Westwood N, Spyvee M, Frost C, Linnane P, Tavares F, Lynch V. Taxane diterpenes 5: Synthesis of the A- and C-rings: An unusual rearrangement of an N-hydroxyimino lactone Tetrahedron. 55: 6435-6452. DOI: 10.1016/S0040-4020(99)00305-1  0.528
1998 Wilmouth RC, Westwood NJ, Anderson K, Brownlee W, Claridge TD, Clifton IJ, Pritchard GJ, Aplin RT, Schofield CJ. Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex. Biochemistry. 37: 17506-13. PMID 9860865 DOI: 10.1021/Bi9816249  0.575
1997 Wilmouth RC, Clifton IJ, Robinson CV, Roach PL, Aplin RT, Westwood NJ, Hajdu J, Schofield CJ. Structure of a specific acyl-enzyme complex formed between beta-casomorphin-7 and porcine pancreatic elastase. Nature Structural Biology. 4: 456-62. PMID 9187653 DOI: 10.1038/Nsb0697-456  0.579
1997 Adlington RM, Baldwin JE, MC Coull W, Pritchard GJ, Schofield CJ, Westwood NJ. An Investigation of the N-Arylsulfonylation of 2-Azetidinones Synthetic Communications. 27: 3803-3813. DOI: 10.1080/00397919708007305  0.473
1997 Westwood NJ, Claridge TD, Edwards PN, Schofield CJ. Reversible acylation of elastase by γ-lactam analogues of β-lactam inhibitors Bioorganic & Medicinal Chemistry Letters. 7: 2973-2978. DOI: 10.1016/S0960-894X(97)10123-8  0.376
1997 Magnus P, Tavares F, Westwood N. Enantioselective synthesis of a taxane C-ring component using the Schultz asymmetric Birch reduction methodology Tetrahedron Letters. 38: 1341-1344. DOI: 10.1016/S0040-4039(97)00094-4  0.516
1996 Magnus P, Ujjainwalla F, Westwood N, Lynch V. Isomerization, autooxidation and epimerization for the introduction of C-1 to C-5 functionality into the taxane ABC ring system Tetrahedron Letters. 37: 6639-6642. DOI: 10.1016/S0040-4039(96)01495-5  0.479
1994 Aplin RT, Robinson CV, Schofield CJ, Westwood NJ. Does the observation of noncovalent complexes between biomolecules by electrospray ionisation mass spectrometry necessarily reflect specific solution interactions? Journal of the Chemical Society, Chemical Communications. 2415-2417. DOI: 10.1039/C39940002415  0.365
1993 Aplin RT, Robinson CV, Schofield CJ, Westwood NJ. An investigation into the mechanism of elastase inhibition by cephalosporins using electrospray ionisation mass spectrometry Tetrahedron. 49: 10903-10912. DOI: 10.1016/S0040-4020(01)80243-X  0.34
1992 Aplin RT, Robinson CV, Schofield CJ, Westwood NJ. Studies on the inhibition of porcine pancreatic elastase using electrospray mass spectrometry Journal of the Chemical Society, Chemical Communications. 1650-1652. DOI: 10.1039/C39920001650  0.323
Low-probability matches (unlikely to be authored by this person)
1998 Magnus P, Ujjainwalla F, Westwood N, Lynch V. Taxane diterpenes 4: Autoxidation, epimerization and isomerization for the introduction of functionality into the taxane ABC ring system Tetrahedron. 54: 3069-3092. DOI: 10.1016/S0040-4020(98)00056-8  0.287
2007 Evans KM, Haraldsen JD, Pearson RJ, Slawin AM, Ward GE, Westwood NJ. Synthesis and chemical characterisation of target identification reagents based on an inhibitor of human cell invasion by the parasite Toxoplasma gondii. Organic & Biomolecular Chemistry. 5: 2063-9. PMID 17581649 DOI: 10.1039/b704685e  0.274
1999 Magnus P, Westwood N. Ireland-Claisen rearrangement for the stereoselective formation of the C2-C3 bond in taxanes Tetrahedron Letters. 40: 4659-4662. DOI: 10.1016/S0040-4039(99)00828-X  0.27
2015 Deuss PJ, Scott M, Tran F, Westwood NJ, de Vries JG, Barta K. Aromatic Monomers by in Situ Conversion of Reactive Intermediates in the Acid-Catalyzed Depolymerization of Lignin. Journal of the American Chemical Society. 137: 7456-67. PMID 26001165 DOI: 10.1021/Jacs.5B03693  0.268
2012 McCarthy AR, Pirrie L, Hollick JJ, Ronseaux S, Campbell J, Higgins M, Staples OD, Tran F, Slawin AM, Lain S, Westwood NJ. Synthesis and biological characterisation of sirtuin inhibitors based on the tenovins. Bioorganic & Medicinal Chemistry. 20: 1779-93. PMID 22304848 DOI: 10.1016/j.bmc.2012.01.001  0.251
2009 Jones AM, Lebl T, Patterson S, van Mourik T, Früchtl HA, Philp D, Slawin AMZ, Westwood NJ. Parallel synthesis and spectroscopic analysis of a collection of heterocycles based on the diazabenz[e]aceanthrylene core structure Tetrahedron. 65: 563-578. DOI: 10.1016/J.Tet.2008.10.049  0.248
2013 Tran F, Odell AV, Ward GE, Westwood NJ. A modular approach to triazole-containing chemical inducers of dimerisation for yeast three-hybrid screening. Molecules (Basel, Switzerland). 18: 11639-57. PMID 24064457 DOI: 10.3390/molecules180911639  0.248
2008 Lucas-Lopez C, Allingham JS, Lebl T, Lawson CP, Brenk R, Sellers JR, Rayment I, Westwood NJ. The small molecule tool (S)-(-)-blebbistatin: novel insights of relevance to myosin inhibitor design. Organic & Biomolecular Chemistry. 6: 2076-84. PMID 18528569 DOI: 10.1039/B801223G  0.247
2018 Ricci F, Carrassa L, Christodoulou MS, Passarella D, Michel B, Benhida R, Martinet N, Hunyadi A, Ioannou E, Roussis V, Musso L, Dallavalle S, Silvestri R, Westwood N, Mori M, et al. A high-throughput screening of a chemical compound library in ovarian cancer stem cells. Combinatorial Chemistry & High Throughput Screening. PMID 29366408 DOI: 10.2174/1386207321666180124093406  0.236
2016 Zurnic I, Hütter S, Lehmann U, Stanke N, Reh J, Kern T, Lindel F, Gerresheim G, Hamann M, Müllers E, Lesbats P, Cherepanov P, Serrao E, Engelman A, Lindemann D, ... ... Westwood N, et al. Proceedings of the Frontiers of Retrovirology Conference 2016 Retrovirology. 13. DOI: 10.1186/S12977-016-0294-5  0.234
2011 Lawson CP, Slawin AM, Westwood NJ. Application of the copper catalysed N-arylation of amidines in the synthesis of analogues of the chemical tool, blebbistatin. Chemical Communications (Cambridge, England). 47: 1057-9. PMID 21079840 DOI: 10.1039/c0cc03624b  0.233
2005 Pearson RJ, Evans KM, Slawin AM, Philp D, Westwood NJ. Controlling the outcome of an N-alkylation reaction by using N-oxide functional groups. The Journal of Organic Chemistry. 70: 5055-61. PMID 15960505 DOI: 10.1021/Jo0503106  0.231
2008 Catti F, Kiuru PS, Slawin AM, Westwood NJ. The synthesis of highly functionalised pyridines using Ghosez-type reactions of dihydropyrazoles. Tetrahedron. 64: 9561-9566. PMID 19794812 DOI: 10.1016/j.tet.2008.07.063  0.23
2009 Makiyi EF, Frade RF, Lebl T, Jaffray EG, Cobb SE, Harvey AL, Slawin AM, Hay RT, Westwood NJ. Iso-seco-tanapartholides: Isolation, Synthesis and Biological Evaluation. European Journal of Organic Chemistry. 2009: 5711-5715. PMID 23606807 DOI: 10.1002/ejoc.200901016  0.23
2015 Lancefield CS, Slawin AM, Westwood NJ, Lebl T. The use of residual dipolar coupling for conformational analysis of structurally related natural products. Magnetic Resonance in Chemistry : Mrc. 53: 467-75. PMID 25854705 DOI: 10.1002/mrc.4213  0.227
2013 Groves MJ, Johnson CE, James J, Prescott AR, Cunningham J, Haydock S, Pepper C, Fegan C, Pirrie L, Westwood NJ, Coates PJ, Ganley IG, Tauro S. p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia. British Journal of Cancer. 109: 2434-44. PMID 24091621 DOI: 10.1038/Bjc.2013.601  0.226
2015 Oueis E, Mann G, Ludwig H, Adamson C, Redpath P, Migaud M, Westwood N, Naismith JH. Derivatisable cyanobactin analogues: a semi-synthetic approach. Chembiochem : a European Journal of Chemical Biology. PMID 26507241 DOI: 10.1002/Cbic.201500494  0.224
2012 Lancefield CS, Zhou L, Lébl T, Slawin AM, Westwood NJ. The synthesis of melohenine B and a related natural product. Organic Letters. 14: 6166-9. PMID 23214465 DOI: 10.1021/ol302859j  0.221
2005 Lucas-Lopez C, Patterson S, Blum T, Straight AF, Toth J, Slawin AMZ, Mitchison TJ, Sellers JR, Westwood NJ. Absolute stereochemical assignment and fluorescence tuning of the small molecule tool, (-)-blebbistatin European Journal of Organic Chemistry. 1736-1740. DOI: 10.1002/Ejoc.200500103  0.221
2018 Oueis E, Stevenson H, Jaspars M, Westwood NJ, Naismith JH. Bypassing the proline/thiazoline requirement of the macrocyclase PatG. Chemical Communications (Cambridge, England). 53: 12274-12277. PMID 29090689 DOI: 10.1039/C7Cc06550G  0.221
2009 Medda F, Russell RJ, Higgins M, McCarthy AR, Campbell J, Slawin AM, Lane DP, Lain S, Westwood NJ. Novel cambinol analogs as sirtuin inhibitors: synthesis, biological evaluation, and rationalization of activity. Journal of Medicinal Chemistry. 52: 2673-82. PMID 19419202 DOI: 10.1021/Jm8014298  0.219
2011 Jones AM, Liu G, Lorion MM, Patterson S, Lebl T, Slawin AM, Westwood NJ. Asymmetric catalytic oxidative cleavage of polycyclic systems: the synthesis of atropisomeric diazonanes and diazecanes. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 5714-8. PMID 21469229 DOI: 10.1002/chem.201003188  0.212
2007 Evans KM, Slawin AM, Lebl T, Philp D, Westwood NJ. An improved understanding of the reaction of bis(bromomethyl)quinoxaline 1-N-oxides with amines using substituent effects. The Journal of Organic Chemistry. 72: 3186-93. PMID 17407354 DOI: 10.1021/Jo062380Y  0.206
2010 McIntyre NA, McInnes C, Griffiths G, Barnett AL, Kontopidis G, Slawin AM, Jackson W, Thomas M, Zheleva DI, Wang S, Blake DG, Westwood NJ, Fischer PM. Design, synthesis, and evaluation of 2-methyl- and 2-amino-N-aryl-4,5-dihydrothiazolo[4,5-h]quinazolin-8-amines as ring-constrained 2-anilino-4-(thiazol-5-yl)pyrimidine cyclin-dependent kinase inhibitors. Journal of Medicinal Chemistry. 53: 2136-45. PMID 20146435 DOI: 10.1021/Jm901660C  0.204
2015 Figuera-Losada M, Stathis M, Dorskind JM, Thomas AG, Bandaru VV, Yoo SW, Westwood NJ, Rogers GW, McArthur JC, Haughey NJ, Slusher BS, Rojas C. Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties. Plos One. 10: e0124481. PMID 26010541 DOI: 10.1371/Journal.Pone.0124481  0.202
2010 Jones AM, Lorion MM, Lebl T, Slawin AMZ, Philp D, Westwood NJ. The chemical reactivity of a known anti-psoriasis drug. Part 1: Further insights into the products resulting from oxidative cleavage Tetrahedron. 66: 9667-9674. DOI: 10.1016/J.Tet.2010.10.044  0.195
2012 Brear P, Telford J, Taylor GL, Westwood NJ. Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem : a European Journal of Chemical Biology. 13: 2374-83. PMID 23070966 DOI: 10.1002/Cbic.201200433  0.188
2011 Walton JG, Jones DC, Kiuru P, Durie AJ, Westwood NJ, Fairlamb AH. Synthesis and evaluation of indatraline-based inhibitors for trypanothione reductase. Chemmedchem. 6: 321-8. PMID 21275055 DOI: 10.1002/cmdc.201000442  0.188
2010 Voûte N, Philp D, Slawin AM, Westwood NJ. Studies on the Claisen rearrangements in the indolo[2,3-b]quinoline system. Organic & Biomolecular Chemistry. 8: 442-50. PMID 20066282 DOI: 10.1039/B915677A  0.185
2011 Medda F, Joseph TL, Pirrie L, Higgins M, Slawin AMZ, Lain S, Verma C, Westwood NJ. N1-Benzyl substituted cambinol analogues as isozyme selective inhibitors of the sirtuin family of protein deacetylases Medchemcomm. 2: 611-615. DOI: 10.1039/C1Md00023C  0.184
2002 Ward GE, Carey KL, Westwood NJ. Using small molecules to study big questions in cellular microbiology. Cellular Microbiology. 4: 471-82. PMID 12174082 DOI: 10.1046/j.1462-5822.2002.00205.x  0.183
2008 Lain S, Hollick JJ, Campbell J, Staples OD, Higgins M, Aoubala M, McCarthy A, Appleyard V, Murray KE, Baker L, Thompson A, Mathers J, Holland SJ, Stark MJ, Pass G, ... ... Westwood NJ, et al. Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell. 13: 454-63. PMID 18455128 DOI: 10.1016/J.Ccr.2008.03.004  0.183
2005 Riggs RL, Morton CJH, Slawin AMZ, Smith DM, Westwood NJ, Austen WSD, Stuart KE. Synthetic studies related to diketopyrrolopyrrole (DPP) pigments. Part 3: Syntheses of tri- and tetra-aryl DPPs Tetrahedron. 61: 11230-11243. DOI: 10.1016/j.tet.2005.09.005  0.181
2005 Morton CJH, Riggs RL, Smith DM, Westwood NJ, Lightfoot P, Slawin AMZ. Synthetic studies related to diketopyrrolopyrrole (DPP) pigments. Part 2: The use of esters in place of nitriles in standard DPP syntheses: Claisen-type acylations and furopyrrole intermediates Tetrahedron. 61: 727-738. DOI: 10.1016/j.tet.2004.10.027  0.179
2012 Pirrie L, McCarthy AR, Major LL, Morkūnaitė V, Zubrienė A, Matulis D, Lain S, Lebl T, Westwood NJ. Discovery and validation of SIRT2 inhibitors based on tenovin-6: use of a ¹H-NMR method to assess deacetylase activity. Molecules (Basel, Switzerland). 17: 12206-24. PMID 23079492 DOI: 10.3390/molecules171012206  0.175
2014 Müller I, Larsson K, Frenzel A, Oliynyk G, Zirath H, Prochownik EV, Westwood NJ, Henriksson MA. Targeting of the MYCN protein with small molecule c-MYC inhibitors. Plos One. 9: e97285. PMID 24859015 DOI: 10.1371/journal.pone.0097285  0.173
1998 Westwood NB, Walker RT. Synthesis and biological properties of a new series of 5-substituted- pyrimidine-L-nucleoside analogues Tetrahedron. 54: 13391-13404. DOI: 10.1016/S0040-4020(98)00821-7  0.173
2014 Leung JM, Tran F, Pathak RB, Poupart S, Heaslip AT, Ballif BA, Westwood NJ, Ward GE. Identification of T. gondii myosin light chain-1 as a direct target of TachypleginA-2, a small-molecule inhibitor of parasite motility and invasion. Plos One. 9: e98056. PMID 24892871 DOI: 10.1371/journal.pone.0098056  0.171
2014 Tilley LD, Krishnamurthy S, Westwood NJ, Ward GE. Identification of TgCBAP, a novel cytoskeletal protein that localizes to three distinct subcompartments of the Toxoplasma gondii pellicle. Plos One. 9: e98492. PMID 24887026 DOI: 10.1371/journal.pone.0098492  0.166
1998 Basnak I, Otter GP, Duncombe RJ, Westwood NB, Pietrarelli M, Hardy GW, Mills G, Rahim SG, Walker RT. Efficient syntheses of (E)-5-(2-bromovinyl)-2'-deoxy-4'-thiouridine; a nucleoside analogue with potent biological activity. Nucleosides & Nucleotides. 17: 29-38. PMID 9708340 DOI: 10.1080/07328319808005155  0.165
2013 Alphey MS, Pirrie L, Torrie LS, Boulkeroua WA, Gardiner M, Sarkar A, Maringer M, Oehlmann W, Brenk R, Scherman MS, McNeil M, Rejzek M, Field RA, Singh M, Gray D, ... Westwood NJ, et al. Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa. Acs Chemical Biology. 8: 387-96. PMID 23138692 DOI: 10.1021/Cb300426U  0.164
2008 Staples OD, Hollick JJ, Campbell J, Higgins M, McCarthy AR, Appleyard V, Murray KE, Baker L, Thompson A, Ronseaux S, Slawin AM, Lane DP, Westwood NJ, Lain S. Characterization, chemical optimization and anti-tumour activity of a tubulin poison identified by a p53-based phenotypic screen. Cell Cycle (Georgetown, Tex.). 7: 3417-27. PMID 18971638 DOI: 10.4161/Cc.7.21.6982  0.161
2011 Pasinszki T, Westwood NPC. Synthesis, spectroscopy, and applications of small nitrile oxides Current Organic Chemistry. 15: 1720-1733.  0.16
2009 Jahan N, Potter JA, Sheikh MA, Botting CH, Shirran SL, Westwood NJ, Taylor GL. Insights into the biosynthesis of the Vibrio cholerae major autoinducer CAI-1 from the crystal structure of the PLP-dependent enzyme CqsA. Journal of Molecular Biology. 392: 763-73. PMID 19631226 DOI: 10.1016/J.Jmb.2009.07.042  0.159
1997 Barclay TM, Cordes AW, De Laat RH, Goddard JD, Haddon RC, Jeter DY, Mawhinney RC, Oakley RT, Palstra TTM, Patenaude GW, Reed RW, Westwood NPC. The heterocyclic diradical benzo-1,2:4,5-bis(1,3,2-dithiazolyl). Electronic, molecular and solid state structure Journal of the American Chemical Society. 119: 2633-2641. DOI: 10.1021/Ja9636294  0.158
2015 Schölz C, Weinert BT, Wagner SA, Beli P, Miyake Y, Qi J, Jensen LJ, Streicher W, McCarthy AR, Westwood NJ, Lain S, Cox J, Matthias P, Mann M, Bradner JE, et al. Acetylation site specificities of lysine deacetylase inhibitors in human cells. Nature Biotechnology. 33: 415-23. PMID 25751058 DOI: 10.1038/Nbt.3130  0.157
2002 Humphries J, Burnand KG, Cunningham P, Brock A, Westwood N, Smith A. Identification of potentially effective antisense oligodeoxyribonucleotide (ODN) sequences for inhibiting plasminogen activator inhibitor-2 (PAI-2) production by monocytes. Thrombosis and Haemostasis. 88: 131-6. PMID 12152653  0.157
2014 Liu G, Lancefield CS, Lorion MM, Slawin AMZ, Westwood NJ. Synthesis and oxidative cleavage of oxazinocarbazoles: Atropselective access to medium-sized rings Synthesis (Germany). 46: 2808-2814. DOI: 10.1055/s-0034-1378530  0.157
2009 Walton JGA, Patterson S, Liu G, Haraldsen JD, Hollick JJ, Slawin AMZ, Ward GE, Westwood NJ. Synthesis and biological evaluation of functionalised tetrahydro-β- carboline analogues as inhibitors of Toxoplasma gondii invasion Organic and Biomolecular Chemistry. 7: 3049-3060. DOI: 10.1039/b902319d  0.153
1993 DeLaat RH, Durham L, Livingstone EG, Westwood NPC. The NSCl/AgNCO reaction: A He I photoelectron, photoionization mass spectroscopy, mid-infrared, and ab initio study of the gaseous S2N2CO molecule Journal of Physical Chemistry. 97: 11216-11220.  0.152
2009 Haraldsen JD, Liu G, Botting CH, Walton JG, Storm J, Phalen TJ, Kwok LY, Soldati-Favre D, Heintz NH, Müller S, Westwood NJ, Ward GE. IDENTIFICATION OF CONOIDIN A AS A COVALENT INHIBITOR OF PEROXIREDOXIN II. Organic & Biomolecular Chemistry. 7: 3040-3048. PMID 21359112 DOI: 10.1039/B901735F  0.146
2011 van Leeuwen IM, Higgins M, Campbell J, Brown CJ, McCarthy AR, Pirrie L, Westwood NJ, Laín S. Mechanism-specific signatures for small-molecule p53 activators. Cell Cycle (Georgetown, Tex.). 10: 1590-8. PMID 21490429 DOI: 10.4161/cc.10.10.15519  0.144
2015 Lancefield CS, Ojo OS, Tran F, Westwood NJ. Isolation of functionalized phenolic monomers through selective oxidation and C-O bond cleavage of the β-O-4 linkages in lignin. Angewandte Chemie (International Ed. in English). 54: 258-62. PMID 25377996 DOI: 10.1002/anie.201409408  0.144
2010 McCarthy AR, Hollick JJ, Westwood NJ. The discovery of nongenotoxic activators of p53: building on a cell-based high-throughput screen. Seminars in Cancer Biology. 20: 40-5. PMID 20206696 DOI: 10.1016/j.semcancer.2010.02.007  0.142
2010 Lebl T, Lorion MM, Jones AM, Philp D, Westwood NJ. Synthesis and characterisation of medium-sized ring systems by oxidative cleavage. Part 2: Insights from the study of ring expanded analogues Tetrahedron. 66: 9694-9702. DOI: 10.1016/J.Tet.2010.10.043  0.142
1991 Hitchcock AP, DeWitte RS, Van Esbroeck JM, Aebi P, Frenc CL, Oakley RT, Westwood NPC. A valence- and inner-shell electronic and photoelectron spectroscopic study of the frontier orbitals of 2,1,3-benzothiadiazole, C6H4SN2, 1,3,2,4-benzodithiadiazine, C6H4S2N2, and 1,3,5,2,4-benzotrithiadiazepine, C6H4S3N2 Journal of Electron Spectroscopy and Related Phenomena. 57: 165-187. DOI: 10.1016/0368-2048(91)85021-K  0.139
2013 MacCallum SF, Groves MJ, James J, Murray K, Appleyard V, Prescott AR, Drbal AA, Nicolaou A, Cunningham J, Haydock S, Ganley IG, Westwood NJ, Coates PJ, Lain S, Tauro S. Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6. Scientific Reports. 3: 1275. PMID 23429453 DOI: 10.1038/srep01275  0.138
2004 Carey KL, Westwood NJ, Mitchison TJ, Ward GE. A small-molecule approach to studying invasive mechanisms of Toxoplasma gondii. Proceedings of the National Academy of Sciences of the United States of America. 101: 7433-8. PMID 15123807 DOI: 10.1073/Pnas.0307769101  0.136
2004 Morgan RE, Westwood NJ. Screening and synthesis: high throughput technologies applied to parasitology. Parasitology. 128: S71-9. PMID 16454900 DOI: 10.1017/S0031182004007073  0.134
2013 Zhou L, Stewart G, Rideau E, Westwood NJ, Smith TK. A class of 5-nitro-2-furancarboxylamides with potent trypanocidal activity against Trypanosoma brucei in vitro. Journal of Medicinal Chemistry. 56: 796-806. PMID 23281892 DOI: 10.1021/jm301215e  0.133
2005 Berkson RG, Hollick JJ, Westwood NJ, Woods JA, Lane DP, Lain S. Pilot screening programme for small molecule activators of p53. International Journal of Cancer. Journal International Du Cancer. 115: 701-10. PMID 15729694 DOI: 10.1002/Ijc.20968  0.133
2005 Havasi B, Pasinszki T, Westwood NP. Gas-phase infrared and ab initio study of the unstable CF3CNO molecule and its stable furoxan ring dimer. The Journal of Physical Chemistry. A. 109: 3864-74. PMID 16833703 DOI: 10.1021/jp040725f  0.132
2000 Brownridge S, Du H, Fairhurst SA, Haddon RC, Oberhammer H, Parsons S, Passmore J, Schriver MJ, Sutcliffe LH, Westwood NPC. The isolation, characterisation, gas phase electron diffraction and crystal structure of the thermally stable radical [CF3CSNSCCF3] Journal of the Chemical Society, Dalton Transactions. 3365-3382. DOI: 10.1039/B001489N  0.131
2016 Lancefield CS, Rashid GMM, Bouxin F, Wasak A, Tu W, Hallett J, Zein S, Rodríguez J, Jackson SD, Westwood NJ, Bugg TDH. Investigation of the Chemocatalytic and Biocatalytic Valorization of a Range of Different Lignin Preparations: The Importance of β-O-4 Content Acs Sustainable Chemistry & Engineering. 4: 6921-6930. DOI: 10.1021/Acssuschemeng.6B01855  0.129
2013 McCarthy AR, Sachweh MC, Higgins M, Campbell J, Drummond CJ, van Leeuwen IM, Pirrie L, Ladds MJ, Westwood NJ, Laín S. Tenovin-D3, a novel small-molecule inhibitor of sirtuin SirT2, increases p21 (CDKN1A) expression in a p53-independent manner. Molecular Cancer Therapeutics. 12: 352-60. PMID 23322738 DOI: 10.1158/1535-7163.MCT-12-0900  0.127
2012 Pasinszki T, Vass G, Klapstein D, Westwood NP. Generation, spectroscopy, and structure of cyanoformyl chloride and cyanoformyl bromide, XC(O)CN. The Journal of Physical Chemistry. A. 116: 3396-403. PMID 22409314 DOI: 10.1021/Jp301528Q  0.126
2004 Westwood NJ. Chemical genetics: how does it function? Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 362: 2761-74. PMID 15539369 DOI: 10.1098/rsta.2004.1467  0.123
1998 Pasinszki T, Westwood NPC. Unstable chloronitrile oxide, ClCNO, and its stable ring dimer: Generation, spectroscopy, and structure Journal of Physical Chemistry A. 102: 4939-4947.  0.123
2004 Patterson S, Lorenz C, Slawin AMZ, Westwood NJ. Rapid access to a pentacyclic library core structure: A microwave assisted approach Qsar and Combinatorial Science. 23: 883-890. DOI: 10.1002/qsar.200420047  0.119
1994 Alaee M, Westwood NPC. Ultraviolet photoelectron studies of dehydration and dehydrohalogenation reactions of β-substituted alcohols using H-ZSM-5 and the formation of unstable intermediates Journal of Physical Chemistry. 98: 3818-3821.  0.117
2010 Heaslip AT, Leung JM, Carey KL, Catti F, Warshaw DM, Westwood NJ, Ballif BA, Ward GE. A small-molecule inhibitor of T. gondii motility induces the posttranslational modification of myosin light chain-1 and inhibits myosin motor activity. Plos Pathogens. 6: e1000720. PMID 20084115 DOI: 10.1371/journal.ppat.1000720  0.116
2012 Zhou L, Ishizaki H, Spitzer M, Taylor KL, Temperley ND, Johnson SL, Brear P, Gautier P, Zeng Z, Mitchell A, Narayan V, McNeil EM, Melton DW, Smith TK, Tyers M, ... Westwood NJ, et al. ALDH2 mediates 5-nitrofuran activity in multiple species. Chemistry & Biology. 19: 883-92. PMID 22840776 DOI: 10.1016/J.Chembiol.2012.05.017  0.116
1997 Westwood NJ, Claridge TDW, Edwards PN, Schofield CJ. Reversible acylation of elastase by γ-lactam analogues of β-lactam inhibitors Bioorganic and Medicinal Chemistry Letters. 7: 2973-2978.  0.115
1995 Pasinszki T, Westwood NPC. He I photoelectron, photoionization mass spectroscopy, mid-infrared, and ab initio study of the unstable CH3OCN molecule Journal of Physical Chemistry. 99: 1649-1654.  0.115
1997 Brupbacher T, Bohn RK, Jäger W, Gerry MCL, Pasinszki T, Westwood NPC. Microwave spectrum and geometry of cyanogen N-oxide, NCCNO Journal of Molecular Spectroscopy. 181: 316-322. DOI: 10.1006/Jmsp.1996.7180  0.114
2010 Liu G, Botting CH, Evans KM, Walton JA, Xu G, Slawin AM, Westwood NJ. Optimisation of conoidin A, a peroxiredoxin inhibitor. Chemmedchem. 5: 41-5. PMID 19946931 DOI: 10.1002/cmdc.200900391  0.113
1995 Pasinszki T, Westwood NPC. Gas-phase generation of the unstable BrCNO molecule and its stable dibromofuroxan dimer. HeI photoelectron, photoionization mass spectroscopy, mid-infrared, and ab initio studies Journal of Physical Chemistry. 99: 6401-6409.  0.113
2004 Yarrow JC, Perlman ZE, Westwood NJ, Mitchison TJ. A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods. Bmc Biotechnology. 4: 21. PMID 15357872 DOI: 10.1186/1472-6750-4-21  0.111
2001 Pasinszki T, Westwood NPC. Gas-phase spectroscopy of the unstable acetonitrile N-oxide molecule, CH3CNO Journal of Physical Chemistry A. 105: 1244-1253.  0.103
2010 Jiang J, Cole D, Westwood N, Macpherson L, Farzaneh F, Mufti G, Tavassoli M, Gäken J. Crucial roles for protein kinase C isoforms in tumor-specific killing by apoptin. Cancer Research. 70: 7242-52. PMID 20719884 DOI: 10.1158/0008-5472.CAN-10-1204  0.101
2009 Pasinszki T, Havasi B, Hajgató B, Westwood NP. Synthesis, spectroscopy and structure of the parent furoxan (HCNO)2. The Journal of Physical Chemistry. A. 113: 170-6. PMID 19099439 DOI: 10.1021/jp810066r  0.097
2014 Guest RD, Kirillova N, Mowbray S, Gornall H, Rothwell DG, Cheadle EJ, Austin E, Smith K, Watt SM, Kühlcke K, Westwood N, Thistlethwaite F, Hawkins RE, Gilham DE. Definition and application of good manufacturing process-compliant production of CEA-specific chimeric antigen receptor expressing T-cells for phase I/II clinical trial. Cancer Immunology, Immunotherapy : Cii. 63: 133-45. PMID 24190544 DOI: 10.1007/s00262-013-1492-9  0.096
2020 Munick de Albuquerque Fragoso D, Bouxin FP, Montgomery JR, Westwood NJ, Jackson SD. Catalytic depolymerisation of isolated lignin to fine chemicals: Depolymerisation of Kraft lignin Bioresource Technology Reports. 9: 100400. DOI: 10.1016/j.biteb.2020.100400  0.096
2003 Straight AF, Cheung A, Limouze J, Chen I, Westwood NJ, Sellers JR, Mitchison TJ. Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. Science (New York, N.Y.). 299: 1743-7. PMID 12637748 DOI: 10.1126/Science.1081412  0.095
1995 Pasinszki T, Westwood NPC. Gas-phase generation and spectroscopy of the unstable NCCNO molecule Journal of the Chemical Society, Chemical Communications. 1901-1902. DOI: 10.1039/C39950001901  0.095
2017 Shaw L, Somisara DMUK, How RC, Westwood NJ, Bruijnincx PCA, Weckhuysen BM, Kamer PCJ. Electronic and bite angle effects in catalytic C–O bond cleavage of a lignin model compound using ruthenium Xantphos complexes Catalysis Science & Technology. 7: 619-626. DOI: 10.1039/C6CY00518G  0.094
1996 Pasinszki T, Westwood NPC. Open-chain and ring isomers of CN2OS: Ab initio study of structures and stabilities Journal of the Chemical Society - Faraday Transactions. 92: 333-341.  0.094
2009 Prokopi M, Pula G, Mayr U, Devue C, Gallagher J, Xiao Q, Boulanger CM, Westwood N, Urbich C, Willeit J, Steiner M, Breuss J, Xu Q, Kiechl S, Mayr M. Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures. Blood. 114: 723-32. PMID 19369228 DOI: 10.1182/blood-2009-02-205930  0.094
1997 Westwood NJ, Schofield CJ, Claridge TDW. Studies on the reactivity of azetidin-2-ones in phosphate buffer Journal of the Chemical Society - Perkin Transactions 1. 2725-2729.  0.093
1997 Pasinszki T, Westwood NPC. Substituted oximes and furoxans as precursors to unstable nitrile oxides. Electronic and geometric structures by ultraviolet photoelectron spectroscopy, infrared spectroscopy and ab initio calculations Journal of Molecular Structure. 408: 161-169. DOI: 10.1016/S0022-2860(96)09631-7  0.092
2015 Lancefield CS, Westwood NJ. The synthesis and analysis of advanced lignin model polymers Green Chemistry. 17: 4980-4990. DOI: 10.1039/c5gc01334h  0.088
2007 Morgan RE, Evans KM, Patterson S, Catti F, Ward GE, Westwood NJ. Targeting invasion and egress: from tools to drugs? Current Drug Targets. 8: 61-74. PMID 17266531 DOI: 10.2174/138945007779315678  0.088
2018 Higuchi Y, Aoki S, Takenami H, Kamimura N, Takahashi K, Hishiyama S, Lancefield CS, Ojo OS, Katayama Y, Westwood NJ, Masai E. Bacterial catabolism of β-hydroxypropiovanillone and β-hydroxypropiosyringone produced in the reductive cleavage of arylglycerol-β-aryl ether in lignin. Applied and Environmental Microbiology. PMID 29374031 DOI: 10.1128/AEM.02670-17  0.084
1995 Pasinszki T, Westwood NPC. Cyanogen di-N-oxide (ONCCNO): Gas phase generation and a HeI photoelectron, photoionization mass spectroscopy, midinfrared, and Ab initio study Journal of the American Chemical Society. 117: 8425-8430.  0.083
2001 Pasinszki T, Kárpáti T, Westwood NPC. Structure and stability of small nitrile sulfides and their attempted generation from 1,2,5-thiadiazoles Journal of Physical Chemistry A. 105: 6258-6265. DOI: 10.1021/jp010830e  0.083
2000 ter Steege DH, Smits M, de Lange CA, Westwood NP, Peel JB, Visscher L. Resonance-enhanced multiphoton ionisation photoelectron spectroscopy of the ClO radical: the C 2 sigma- state Faraday Discussions. 259-69; discussion 3. PMID 11040512  0.082
1996 Pasinszki T, Westwood NPC. Ground, excited, and ionic states of the NCCNO molecule: A HeI photoelectron, infrared, ultraviolet, and ab initio investigation Journal of Physical Chemistry. 100: 16856-16863.  0.081
1995 Guo B, Pasinszki T, Westwood NPC, Bernath PF. The high resolution infrared spectroscopy of cyanogen di-N-oxide (ONCCNO) The Journal of Chemical Physics. 103: 3335-3340.  0.081
2009 Cheuk AT, Wells JW, Chan L, Westwood NB, Berger SA, Yagita H, Okumura K, Farzaneh F, Mufti GJ, Guinn BA. Anti-tumor immunity in a model of acute myeloid leukemia. Leukemia & Lymphoma. 50: 447-54. PMID 19197726 DOI: 10.1080/10428190802653776  0.079
2016 Chen ASY, Westwood NJ, Brear P, Rogers GW, Mavridis L, Mitchell JBO. A Random Forest Model for Predicting Allosteric and Functional Sites on Proteins Molecular Informatics. DOI: 10.1002/minf.201500108  0.079
2014 Sidik SM, Hackett CG, Tran F, Westwood NJ, Lourido S. Efficient genome engineering of Toxoplasma gondii using CRISPR/Cas9. Plos One. 9: e100450. PMID 24971596 DOI: 10.1371/Journal.Pone.0100450  0.078
1996 Guo B, Pasinszki T, Westwood NPC, Zhang K, Bernath PF. High resolution infrared spectroscopy of cyanogen N-oxide, NCCNO Journal of Chemical Physics. 105: 4457-4460.  0.077
1993 Westwood N, Dudley JM, Sawyer B, Messinezy M, Pearson TC. Primary polycythaemia: diagnosis by non-conventional positive criteria. European Journal of Haematology. 51: 228-32. PMID 8243612  0.077
2000 Pasinszki T, Westwood NPC. Ground, excited and ionic states of unstable molecules Journal of Electron Spectroscopy and Related Phenomena. 108: 63-73. DOI: 10.1016/S0368-2048(00)00146-8  0.072
1995 Westwood NB, Copson ER, Page LA, Mire-Sluis AR, Brown KA, Pearson TC. Activated phenotype in neutrophils and monocytes from patients with primary proliferative polycythaemia. Journal of Clinical Pathology. 48: 525-30. PMID 7545186  0.071
2000 Rijs AM, Backus EHG, De Lange CA, Westwood NPC, Janssen MHM. `Magnetic bottle' spectrometer as a versatile tool for laser photoelectron spectroscopy Journal of Electron Spectroscopy and Related Phenomena. 112: 151-162. DOI: 10.1016/S0368-2048(00)00209-7  0.07
1992 Ward CS, Westwood NB, Emmerson AJB, Pearson TC. The in vitro effect of high-dose recombinant human erythropoietin on granulocyte-macrophage colony production in premature infants using a defined serum deprived cell culture system British Journal of Haematology. 81: 325-330. PMID 1382542  0.067
1997 Pasinszki T, Westwood NPC. Structure and spectroscopy of dihaloformaldoximes: He I photoelectron, photoionization mass spectroscopy, mid-IR, Raman and ab initio study Journal of the Chemical Society - Faraday Transactions. 93: 43-51.  0.065
1997 Adlington RM, Baldwin JE, McCoull W, Pritchard GJ, Schofield CJ, Westwood NJ. An investigation of the N-arylsulfonylation of 2-azetidinones Synthetic Communications. 27: 3803-3813.  0.065
1995 Acharya J, Westwood NB, Sawyer BM, Messinezy M, Burroughs AK, Mehta AB, Pearson TC. Identification of latent myeloproliferative disease in patients with Budd-Chiari syndrome using X-chromosome inactivation patterns and in vitro erythroid colony formation. European Journal of Haematology. 55: 315-21. PMID 7493678  0.064
2000 Ter Steege DHA, Smits M, De Lange CA, Westwood NPC, Peel JB, Visscher L. Resonance-enhanced multiphoton ionisation photoelectron spectroscopy of the ClO radical: The C 2Σ- state Faraday Discussions. 115: 259-269.  0.063
1990 Alaee M, Hofstra P, Kirby C, Westwood NPC. He I photoelectron spectra of unstable boron isocyanates; electronic and geometric structures in the BClx(NCO)3-x series Journal of the Chemical Society, Dalton Transactions. 1569-1573. DOI: 10.1039/DT9900001569  0.062
1994 Messinezy M, Westwood N, Sawyer B, Grace R, Holland LJ, Lawrie AS, Pearson TC. Primary thrombocythaemia: a composite approach to diagnosis. Clinical and Laboratory Haematology. 16: 139-48. PMID 7955922  0.059
2015 Bouxin FP, McVeigh A, Tran F, Westwood NJ, Jarvis MC, Jackson SD. Catalytic depolymerisation of isolated lignins to fine chemicals using a Pt/alumina catalyst: Part 1 - Impact of the lignin structure Green Chemistry. 17: 1235-1242. DOI: 10.1039/c4gc01678e  0.057
1993 Cordes AW, Bryan CD, Davis WM, De Laat RH, Glarum SH, Goddard JD, Haddon RC, Hicks RG, Kennepohl DK, Oakley RT, Scott SR, Westwood NPC. Prototypal 1,2,3,5-dithia- and 1,2,3,5-diselenadiazolyl [HCN2E2]. (E = S, Se): Molecular and electronic structures of the radicals and their dimers, by theory and experiment Journal of the American Chemical Society. 115: 7232-7239.  0.056
2002 Rijs AM, Backus EHG, De Lange CA, Janssen MHM, Westwood NPC, Wang K, McKoy V. Rotationally resolved photoionization dynamics of hot CO fragmented from OCS Journal of Chemical Physics. 116: 2776-2782. DOI: 10.1063/1.1434993  0.056
1991 Westwood NB, Barrett Emmerson AJ. Erythropoietic progenitor cells from premature neonates studied using a validated serum-deprived medium - Evidence that peripheral blood BFU-E from premature neonates are increased in number and are highly dependent upon 'Burst Promoting Activity' for in vitro growth Cytotechnology. 6: 241-246. PMID 1367667 DOI: 10.1007/BF00624763  0.055
1994 Messinezy M, Sawyer B, Westwood NB, Pearson TC. Idiopathic erythrocytosis--additional new study techniques suggest a heterogenous group. European Journal of Haematology. 53: 163-7. PMID 7925859  0.054
2002 DeMille S, DeLaat RH, Tanner RM, Brooks RL, Westwood NPC. Comparison of CRDS to ICL-PAS and phase-shift CRDS spectroscopies for the absolute intensities of C-H (ΔνCH = 6) overtone absorptions Chemical Physics Letters. 366: 383-389. DOI: 10.1016/S0009-2614(02)01616-0  0.054
1989 Sammynaiken R, Westwood NPC. HeI photoelectron studies of unstable ketenes: Mono- and Di-phenylketenes, and their gas-phase conformations Journal of the Chemical Society, Perkin Transactions 2. 1987-1992.  0.053
1993 Alaee M, Livingstone EG, Westwood NPC. HeI photoelectron, mid-infrared, and ab initio studies of the unstable fluoroisocyanatoboranes F2BNCO and FB(NCO)2 Journal of the American Chemical Society. 115: 2871-2876.  0.053
2015 Odell AV, Tran F, Foderaro JE, Poupart S, Pathak R, Westwood NJ, Ward GE. Yeast three-hybrid screen identifies TgBRADIN/GRA24 as a negative regulator of Toxoplasma gondii bradyzoite differentiation. Plos One. 10: e0120331. PMID 25789621 DOI: 10.1371/journal.pone.0120331  0.051
2015 Odell AV, Tran F, Foderaro JE, Poupart S, Pathak R, Westwood NJ, Ward GE. Yeast three-hybrid screen identifies TgBRADIN/GRA24 as a negative regulator of toxoplasma gondii bradyzoite differentiation Plos One. 10. DOI: 10.1371/journal.pone.0120331  0.051
1992 Clement SG, Ashfold MNR, Western CM, De Beer E, De Lange CA, Westwood NPC. New singlet Rydberg states of the NH(ND) radical in the energy range 92 000-100 000 cm-1 characterized by resonance enhanced multiphoton ionization-photoelectron spectroscopy The Journal of Chemical Physics. 96: 4963-4973.  0.049
2015 Tran F, Lancefield CS, Kamer PCJ, Lebl T, Westwood NJ. Selective modification of the β-β Linkage in DDQ-treated Kraft lignin analysed by 2D NMR spectroscopy Green Chemistry. 17: 244-249. DOI: 10.1039/c4gc01012d  0.049
1998 Pasinszki T, Westwood NPC. Ultraviolet photoelectron spectroscopy of unstable nitrile oxides Journal of Electron Spectroscopy and Related Phenomena. 97: 15-22.  0.048
2002 Pasinszki T, Westwood NPC. Structure and stability of fluoronitrile oxide, FCNO: A quantum-chemical study Physical Chemistry Chemical Physics. 4: 4298-4304. DOI: 10.1039/b204456k  0.046
2005 Guinn BA, Gilkes AF, Woodward E, Westwood NB, Mufti GJ, Linch D, Burnett AK, Mills KI. Microarray analysis of tumour antigen expression in presentation acute myeloid leukaemia. Biochemical and Biophysical Research Communications. 333: 703-13. PMID 15963951 DOI: 10.1016/j.bbrc.2005.05.161  0.046
2009 Pasinszki T, Hajgató B, Havasi B, Westwood NP. Dimerisation of nitrile oxides: a quantum-chemical study. Physical Chemistry Chemical Physics : Pccp. 11: 5263-72. PMID 19551193 DOI: 10.1039/b823406j  0.045
1997 Christ ER, Cummings MH, Westwood NB, Sawyer BM, Pearson TC, Sönksen PH, Russell-Jones DL. The importance of growth hormone in the regulation of erythropoiesis, red cell mass, and plasma volume in adults with growth hormone deficiency. The Journal of Clinical Endocrinology and Metabolism. 82: 2985-90. PMID 9284731 DOI: 10.1210/jcem.82.9.4199  0.045
2007 Mohamedali A, Gäken J, Twine NA, Ingram W, Westwood N, Lea NC, Hayden J, Donaldson N, Aul C, Gattermann N, Giagounidis A, Germing U, List AF, Mufti GJ. Prevalence and prognostic significance of allelic imbalance by single-nucleotide polymorphism analysis in low-risk myelodysplastic syndromes. Blood. 110: 3365-73. PMID 17634407 DOI: 10.1182/Blood-2007-03-079673  0.043
1991 de Beer E, Born M, de Lange CA, Westwood NPC. A rotationally resolved REMPI-PES study of the NH radical Chemical Physics Letters. 186: 40-46. DOI: 10.1016/0009-2614(91)80189-5  0.04
1991 Abood E, Eridani S, Sawyer B, Westwood N, Pearson TC. Erythropoietin gene expression in haemopoietic cell lines. Cytotechnology. 6: 131-6. PMID 1367406 DOI: 10.1007/BF00373030  0.04
2010 Smith AE, Mohamedali AM, Kulasekararaj A, Lim Z, Gäken J, Lea NC, Przychodzen B, Mian SA, Nasser EE, Shooter C, Westwood NB, Strupp C, Gattermann N, Maciejewski JP, Germing U, et al. Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value. Blood. 116: 3923-32. PMID 20693430 DOI: 10.1182/blood-2010-03-274704  0.04
2010 Westwood NJ, Watson M. Hazards of man-made material to nesting Hawfinches British Birds. 103: 247.  0.039
1992 Wang K, Stephens JA, McKoy V, De Beer E, De Lange CA, Westwood NPC. Rotationally resolved photoelectron spectra in resonance enhanced multiphoton ionization of Rydberg states of NH The Journal of Chemical Physics. 97: 211-221.  0.039
2006 Patel RK, Lea NC, Heneghan MA, Westwood NB, Milojkovic D, Thanigaikumar M, Yallop D, Arya R, Pagliuca A, Gäken J, Wendon J, Heaton ND, Mufti GJ. Prevalence of the activating JAK2 tyrosine kinase mutation V617F in the Budd-Chiari syndrome. Gastroenterology. 130: 2031-8. PMID 16762626 DOI: 10.1053/j.gastro.2006.04.008  0.036
1994 Sawyer BM, Westwood NB, Pearson TC. Circulating megakaryocytic progenitor cells in patients with primary thrombocythaemia and reactive thrombocytosis: results using a serum-deprived culture assay and a positive detection technique. European Journal of Haematology. 53: 108-13. PMID 8088381  0.035
2006 Ceesay MM, Lea NC, Ingram W, Westwood NB, Gäken J, Mohamedali A, Cervera J, Germing U, Gattermann N, Giagounidis A, Garcia-Casado Z, Sanz G, Mufti GJ. The JAK2 V617F mutation is rare in RARS but common in RARS-T. Leukemia. 20: 2060-1. PMID 16932338 DOI: 10.1038/sj.leu.2404373  0.034
2006 Lea NC, Lim Z, Westwood NB, Arno MJ, Gäken J, Mohamedali A, Mufti GJ. Presence of JAK2 V617F tyrosine kinase mutation as a myeloid-lineage-specific mutation in chronic neutrophilic leukaemia. Leukemia. 20: 1324-6. PMID 16673022 DOI: 10.1038/sj.leu.2404240  0.033
1992 Price CM, Kanfer EJ, Colman SM, Westwood N, Barrett AJ, Greaves MF. Simultaneous genotypic and immunophenotypic analysis of interphase cells using dual-color fluorescence: a demonstration of lineage involvement in polycythemia vera. Blood. 80: 1033-8. PMID 1498322  0.032
1989 Cordes AW, Goddard JD, Oakley RT, Westwood NPC. 1,2,3,5-Dithiadiazolium cations and 1,2,3,5-dithiadiazolyl radicals: An ab initio computational, ultraviolet photoelectron spectroscopic, and crystallographic study of a cation/radical pair Journal of the American Chemical Society. 111: 6147-6154. DOI: 10.1021/Ja00198A025  0.031
2009 Van Der Ende BM, Winslade C, Brooks RL, DeLaat RH, Westwood NPC. CRDS study of auto-ionizing Rydberg states of argon in a microwave discharge Canadian Journal of Physics. 87: 575-581. DOI: 10.1139/P08-132  0.03
1994 Copson ER, Westwood NB, Majumdar G. T lymphocyte subpopulations in patients with B-cell chronic lymphocyte leukaemia: relationship to infective episodes. Leukemia & Lymphoma. 14: 441-6. PMID 7812203 DOI: 10.3109/10428199409049701  0.029
1990 Inglis IR, Isaacson AJ, Thearle RJP, Westwood NJ. The effects of changing agricultural practice upon woodpigeon Columba palumbus numbers Ibis. 132: 262-272.  0.028
1990 Pagliuca A, Mufti GJ, Janossa-Tahernia M, Eridani S, Westwood NB, Thumpston J, Sawyer B, Sturgess R, Williams R. In vitro colony culture and chromosomal studies in hepatic and portal vein thrombosis--possible evidence of an occult myeloproliferative state. The Quarterly Journal of Medicine. 76: 981-9. PMID 2236481  0.027
1996 Pasinszki T, Ferguson G, Westwood NPC. Geometric and electronic structure of dicyanofuroxan by experiment and theory Journal of the Chemical Society. Perkin Transactions 2. 2: 179-185.  0.027
1990 Dudley JM, Westwood N, Leonard S, Eridani S, Pearson TC. Primary polycythaemia: Positive diagnosis using the differential response of primitive and mature erythroid progenitors to erythropoietin, interleukin 3 and alpha-interferon British Journal of Haematology. 75: 188-194. PMID 2372504  0.026
1992 de Beer E, de Lange CA, Westwood NP. Resonance-enhanced multiphoton-ionization photoelectron spectroscopy of np and nf Rydberg states of atomic nitrogen. Physical Review. A. 46: 5653-5665. PMID 9908815 DOI: 10.1103/PhysRevA.46.5653  0.026
2003 Newell DR, Searle KM, Westwood NB, Burtles SS. Professor Tom Connors and the development of novel cancer therapies by the Phase I/II Clinical Trials Committee of Cancer Research UK. British Journal of Cancer. 89: 437-54. PMID 12888809 DOI: 10.1038/sj.bjc.6601106  0.026
1997 Eid CN, Halligan NG, Nicas TI, Mullen DL, Butler TF, Loncharich RJ, Paschal JW, Schofield CJ, Westwood NJ, Cheng L. Tripeptide LY301621 and its diastereomers as methicillin potentiators against methicillin resistant Staphylococcus aureus The Journal of Antibiotics. 50: 283-5. PMID 9439706  0.024
1997 Eid CN, Halligan NG, Nicas TI, Mullen DL, Butler TF, Loncharich RJ, Paschal JW, Schofield CJ, Westwood NJ, Cheng L. Tripeptide LY301621 and its diastereomers as methicillin potentiators against methicillin resistant Staphylococcus aureus. The Journal of Antibiotics. 50: 283-5. PMID 9127206  0.024
2000 Pearson TC, Messinezy M, Westwood N, Green AR, Bench AJ, Green AR, Huntly BJ, Nacheva EP, Barbui T, Finazzi G. A Polycythemia Vera Updated: Diagnosis, Pathobiology, and Treatment. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 51-68. PMID 11701535  0.023
2009 Mohamedali AM, Smith AE, Gaken J, Lea NC, Mian SA, Westwood NB, Strupp C, Gattermann N, Germing U, Mufti GJ. Novel TET2 mutations associated with UPD4q24 in myelodysplastic syndrome. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 4002-6. PMID 19528370 DOI: 10.1200/JCO.2009.22.6985  0.023
1989 Chadha-Boreham HK, Westwood N. Drawbacks of selection methods for synchronous cell growth: simulation techniques Ima Journal of Mathematics Applied in Medicine and Biology. 6: 243-255. PMID 2577999  0.023
1992 Cook GC, Heard SE, Pearson TC, Westwood NB. Homozygous haemoglobin O Arab disease and conjugated hyperbilirubinaemia [5] British Medical Journal. 304: 446-447. PMID 1547405  0.023
1994 Copson ER, Ellis BA, Westwood NB, Majumdar G. IgG subclass levels in patients with B cell chronic lymphocytic leukaemia. Leukemia & Lymphoma. 14: 471-3. PMID 7812207 DOI: 10.3109/10428199409049706  0.022
2009 Mitchell R, Kremer A, Westwood N, Younge L, Ghosh S. Talking about life and IBD: A paradigm for improving patient-physician communication. Journal of Crohn's & Colitis. 3: 1-3. PMID 21172240 DOI: 10.1016/j.crohns.2008.07.002  0.022
2012 Smith T, Westwood N, Hunter W, Matthews K. Targeting new drugs with choline metabolism. International Innovation : Disseminating Science, Research and Technology. 18-21. PMID 24443701  0.022
1994 Wales NPL, De Beer E, Westwood NPC, Buma WJ, De Lange CA, Van Hemert MC. One- and two-color two-photon resonance enhanced multiphoton ionization spectroscopy of the d 1Σ+ state of NH The Journal of Chemical Physics. 100: 7984-7994.  0.021
2004 Westwood NJ, Boyd S. Mountain scenic flights: A low risk, low impact ecotourism experience within south island, New Zealand Nature-Based Tourism in Peripheral Areas: Development or Disaster?. 50-63.  0.02
1990 Pennycuik PR, Reisner AH, Westwood NH. Process responsible for temporal changes in the percentages of pelage colour types among the young recruited into a house mouse population in an outdoor pen Australian Journal of Zoology. 38: 105-116.  0.018
1997 Messinezy M, Macdonald LM, Nunan TO, Westwood NB, Chinn S, Pearson TC. Spleen sizing by ultrasound in polycythaemia and thrombocythaemia: comparison with SPECT. British Journal of Haematology. 98: 103-7. PMID 9233571  0.018
2004 Milojkovic D, Devereux S, Westwood NB, Mufti GJ, Thomas NS, Buggins AG. Antiapoptotic microenvironment of acute myeloid leukemia. Journal of Immunology (Baltimore, Md. : 1950). 173: 6745-52. PMID 15557167  0.016
1996 Westwood NN, Scarcella DL, Bryan-Lluka LJ. Evidence for uptake1-mediated efflux of catecholamines from pulmonary endothelial cells of perfused lungs of rats. Naunyn-Schmiedeberg's Archives of Pharmacology. 353: 528-35. PMID 8740146  0.016
1994 Westwood NB, Chung R, Emmerson AJB, Pearson TC. The in vitro effects of stem cell factor, interleukin 3 and granulocyte- macrophage colony stimulating factor on haemopoietic progenitor cells from premature infants British Journal of Haematology. 86: 468-474. PMID 7519035  0.016
1990 Bottomley F, Paez DE, Sutin L, White PS, Köhler FH, Thompson RC, Westwood NPC. Organometallic oxides: Preparation and molecular and electronic structure of antiferromagnetic [(η-C5H5)Cr(μ3-O)]4 and [(η-C5H5)Cr]4(μ3-η 2-C5H4)(μ3-O)3 Organometallics. 9: 2443-2454.  0.016
2000 Westwood NB, Gruszka-Westwood AM, Pearson CE, Delord CF, Green AR, Huntly BJ, Lakhani A, McMullin MF, Pearson TC. The incidences of trisomy 8, trisomy 9 and D20S108 deletion in polycythaemia vera: an analysis of blood granulocytes using interphase fluorescence in situ hybridization. British Journal of Haematology. 110: 839-46. PMID 11054066 DOI: 10.1046/j.1365-2141.2000.02242.x  0.015
1993 Majumdar G, Westwood NB, Bell-witter C, Muggleston D, Phillips J, Pearson TC. Serum erythropoietin and circulating BFU-e in patients with multiple myeloma and anaemia but without renal failure Leukemia and Lymphoma. 9: 173-176. PMID 8477197 DOI: 10.3109/10428199309148523  0.015
1990 Dudley JM, Westwood N, Woodcock S, Pearson TC, Eridani S. Sensitivity of erythroid progenitors to recombinant growth factors in the diagnosis of myeloproliferative disorders International Journal of Cell Cloning. 8: 199-202. PMID 2324555  0.015
1995 Messinezy M, Westwood NB, Woodcock SP, Strong RM, Pearson TC. Low serum erythropoietin--a strong diagnostic criterion of primary polycythaemia even at normal haemoglobin levels. Clinical and Laboratory Haematology. 17: 217-20. PMID 8719893  0.014
1991 Kazemi A, Westwood NB. Platelet separation from the blood of severely thrombocytopenic patients Medical Laboratory Sciences. 48: 232-234. PMID 1787783  0.014
2004 Pradhan A, Mijovic A, Mills K, Cumber P, Westwood N, Mufti GJ, Rassool FV. Differentially expressed genes in adult familial myelodysplastic syndromes. Leukemia. 18: 449-59. PMID 14737073 DOI: 10.1038/sj.leu.2403265  0.013
1991 Chadha-boreham HK, Westwood N, Andrew M. Drawbacks of induction methods for synchronous cell growth: Simulation techniques Mathematical Medicine and Biology. 8: 273-286. DOI: 10.1093/imammb/8.4.273  0.013
2003 Westwood NB, Mufti GJ. Apoptosis in the myelodysplastic syndromes. Current Hematology Reports. 2: 186-92. PMID 12901339  0.011
1996 Westwood NB, Pearson TC. Diagnostic applications of haemopoietic progenitor culture techniques in polycythaemias and thrombocythaemias. Leukemia & Lymphoma. 22: 95-103. PMID 8951779 DOI: 10.3109/10428199609074366  0.011
2002 Buggins AG, Mufti GJ, Salisbury J, Codd J, Westwood N, Arno M, Fishlock K, Pagliuca A, Devereux S. Peripheral blood but not tissue dendritic cells express CD52 and are depleted by treatment with alemtuzumab. Blood. 100: 1715-20. PMID 12176892  0.011
1992 Hodgkinson PH, Luff I, Westwood N. Pharmacy mail exchange: An international electronic mail distribution system for pharmacists International Pharmacy Journal. 6: 225-227.  0.011
1998 Percy MJ, McMullin MF, Roques AW, Westwood NB, Acharya J, Hughes AE, Lappin TR, Pearson TC. Erythrocytosis due to a mutation in the erythropoietin receptor gene. British Journal of Haematology. 100: 407-10. PMID 9488636  0.01
2009 Gaken J, Mohamedali A, Twine N, Westwood N, Czepulkowski B, Chehade S, Lea N, Quek L, Mufti G. P054 MicroRNA expression profiling of high and low risk MDS Leukemia Research. 33: S90. DOI: 10.1016/S0145-2126(09)70134-1  0.01
2008 Westwood N, Travis SP. Review article: what do patients with inflammatory bowel disease want for their clinical management? Alimentary Pharmacology & Therapeutics. 27: 1-8. PMID 18307643 DOI: 10.1111/j.1365-2036.2008.03605.x  0.01
2006 Ingram W, Lea NC, Cervera J, Germing U, Fenaux P, Cassinat B, Kiladjian JJ, Varkonyi J, Antunovic P, Westwood NB, Arno MJ, Mohamedali A, Gaken J, Kontou T, Czepulkowski BH, et al. The JAK2 V617F mutation identifies a subgroup of MDS patients with isolated deletion 5q and a proliferative bone marrow. Leukemia. 20: 1319-21. PMID 16617322 DOI: 10.1038/sj.leu.2404215  0.01
2002 Messinezy M, Westwood NB, El-Hemaidi I, Marsden JT, Sherwood RS, Pearson TC. Serum erythropoietin values in erythrocytoses and in primary thrombocythaemia. British Journal of Haematology. 117: 47-53. PMID 11918532 DOI: 10.1046/j.1365-2141.2002.03386.x  0.01
2001 Westwood NB, Gruszka-Westwood AM, Atkinson S, Pearson TC. Polycythemia vera: analysis of DNA from blood granulocytes using comparative genomic hybridization. Haematologica. 86: 464-9. PMID 11410408  0.01
1996 Pearson TC, Messinezy M, Westwood N. Polycythemia: Diagnostic aspects and classification European Journal of Laboratory Medicine. 4: 129-135.  0.01
1993 Westwood NN, Bryan-Lluka LJ. Types A and B monoamine oxidase contribute to the metabolism of norepinephrine in perfused lungs of rats Journal of Pharmacology and Experimental Therapeutics. 267: 815-821. PMID 8246156  0.01
1992 Bryan-Lluka LJ, Westwood NN, O'Donnell SR. Vascular uptake of catecholamines in perfused lungs of the rat occurs by the same process as Uptake1 in noradrenergic neurones Naunyn-Schmiedeberg's Archives of Pharmacology. 345: 319-326. PMID 1535692 DOI: 10.1007/BF00168693  0.01
1991 Emmerson AJ, Westwood NB, Rackham RA, Stern CM, Pearson TC. Erythropoietin responsive progenitors in anaemia of prematurity. Archives of Disease in Childhood. 66: 810-1. PMID 1863130 DOI: 10.1136/adc.66.7_Spec_No.810  0.01
1991 Heard SE, Westwood NB, Pearson TC, Stephens AD. Homozygous haemoglobin O-Arab in pregnancy [1] Clinical and Laboratory Haematology. 13: 319-320. PMID 1794236  0.01
1989 Mckendrick D, Farmer A, Kay JS, Hodgkinson P, Westwood N. COMPUTER NETWORKS IN MEDICINE The Lancet. 334: 1456. DOI: 10.1016/S0140-6736(89)92065-5  0.01
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