Michael Thomas Rudd - Publications

Affiliations: 
1999-2005 Chemistry Stanford University, Palo Alto, CA 

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 McCauley JA, Rudd MT. Hepatitis C virus NS3/4a protease inhibitors. Current Opinion in Pharmacology. 30: 84-92. PMID 27544488 DOI: 10.1016/j.coph.2016.07.015  1
2016 Stachel SJ, Zerbinatti C, Rudd MT, Cosden M, Suon S, Nanda KK, Wessner K, Dimuzio JM, Maxwell J, Wu Z, Uslaner JM, Michener MS, Szczerba P, Brnardic E, Rada V, et al. Identification and In Vivo Evaluation of Liver X Receptor β (LXRβ) Selective Agonists for the Potential Treatment of Alzheimer's Disease. Journal of Medicinal Chemistry. PMID 27011007 DOI: 10.1021/acs.jmedchem.6b00176  1
2015 Rudd MT, Butcher JW, Nguyen KT, McIntyre CJ, Romano JJ, Gilbert KF, Bush KJ, Liverton NJ, Holloway MK, Harper S, Ferrara M, DiFilippo M, Summa V, Swestock J, Fritzen J, et al. P2-quinazolinones and bis-macrocycles as new templates for next-generation hepatitis C virus NS3/4a protease inhibitors: discovery of MK-2748 and MK-6325. Chemmedchem. 10: 727-35. PMID 25759009 DOI: 10.1002/cmdc.201402558  1
2015 Solly K, Klein R, Rudd M, Holloway MK, Johnson EN, Henze D, Finley MF. High-Throughput Screen of GluK1 Receptor Identifies Selective Inhibitors with a Variety of Kinetic Profiles Using Fluorescence and Electrophysiology Assays. Journal of Biomolecular Screening. 20: 708-19. PMID 25700884 DOI: 10.1177/1087057115570580  1
2014 Stachel SJ, Sanders JM, Henze DA, Rudd MT, Su HP, Li Y, Nanda KK, Egbertson MS, Manley PJ, Jones KL, Brnardic EJ, Green A, Grobler JA, Hanney B, Leitl M, et al. Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic pain. Journal of Medicinal Chemistry. 57: 5800-16. PMID 24914455 DOI: 10.1021/jm5006429  1
2014 Shah U, Jayne C, Chackalamannil S, Velázquez F, Guo Z, Buevich A, Howe JA, Chase R, Soriano A, Agrawal S, Rudd MT, McCauley JA, Liverton NJ, Romano J, Bush K, et al. Novel Quinoline-Based P2-P4 Macrocyclic Derivatives As Pan-Genotypic HCV NS3/4a Protease Inhibitors. Acs Medicinal Chemistry Letters. 5: 264-9. PMID 24900818 DOI: 10.1021/ml400466p  1
2012 Harper S, McCauley JA, Rudd MT, Ferrara M, DiFilippo M, Crescenzi B, Koch U, Petrocchi A, Holloway MK, Butcher JW, Romano JJ, Bush KJ, Gilbert KF, McIntyre CJ, Nguyen KT, et al. Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor. Acs Medicinal Chemistry Letters. 3: 332-6. PMID 24900473 DOI: 10.1021/ml300017p  1
2012 Rudd MT, McIntyre CJ, Romano JJ, Butcher JW, Holloway MK, Bush K, Nguyen KT, Gilbert KF, Lyle TA, Liverton NJ, Wan BL, Summa V, Harper S, Rowley M, Vacca JP, et al. Development of macrocyclic inhibitors of HCV NS3/4A protease with cyclic constrained P2-P4 linkers. Bioorganic & Medicinal Chemistry Letters. 22: 7207-13. PMID 23084906 DOI: 10.1016/j.bmcl.2012.09.061  1
2012 Rudd MT, McCauley JA, Romano JJ, Butcher JW, Bush K, McIntyre CJ, Nguyen KT, Gilbert KF, Lyle TA, Holloway MK, Wan BL, Vacca JP, Summa V, Harper S, Rowley M, et al. Development of potent macrocyclic inhibitors of genotype 3a HCV NS3/4A protease. Bioorganic & Medicinal Chemistry Letters. 22: 7201-6. PMID 23021993 DOI: 10.1016/j.bmcl.2012.08.106  1
2012 Summa V, Ludmerer SW, McCauley JA, Fandozzi C, Burlein C, Claudio G, Coleman PJ, Dimuzio JM, Ferrara M, Di Filippo M, Gates AT, Graham DJ, Harper S, Hazuda DJ, Huang Q, ... ... Rudd MT, et al. MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants. Antimicrobial Agents and Chemotherapy. 56: 4161-7. PMID 22615282 DOI: 10.1128/AAC.00324-12  1
2011 Rudd MT, McCauley JA, Butcher JW, Romano JJ, McIntyre CJ, Nguyen KT, Gilbert KF, Bush KJ, Holloway MK, Swestock J, Wan BL, Carroll SS, DiMuzio JM, Graham DJ, Ludmerer SW, et al. Discovery of MK-1220: A Macrocyclic Inhibitor of Hepatitis C Virus NS3/4A Protease with Improved Preclinical Plasma Exposure. Acs Medicinal Chemistry Letters. 2: 207-12. PMID 24900304 DOI: 10.1021/ml1002426  1
2010 McCauley JA, McIntyre CJ, Rudd MT, Nguyen KT, Romano JJ, Butcher JW, Gilbert KF, Bush KJ, Holloway MK, Swestock J, Wan BL, Carroll SS, DiMuzio JM, Graham DJ, Ludmerer SW, et al. Discovery of vaniprevir (MK-7009), a macrocyclic hepatitis C virus NS3/4a protease inhibitor. Journal of Medicinal Chemistry. 53: 2443-63. PMID 20163176 DOI: 10.1021/jm9015526  1
2010 Liverton NJ, Carroll SS, Dimuzio J, Fandozzi C, Graham DJ, Hazuda D, Holloway MK, Ludmerer SW, McCauley JA, McIntyre CJ, Olsen DB, Rudd MT, Stahlhut M, Vacca JP. MK-7009, a potent and selective inhibitor of hepatitis C virus NS3/4A protease. Antimicrobial Agents and Chemotherapy. 54: 305-11. PMID 19841155 DOI: 10.1128/AAC.00677-09  1
2009 Trost BM, Maulide N, Rudd MT. Ruthenium-catalyzed cross-coupling of tertiary propargyl alcohols with omega-alkynenitriles: a regio- and stereoselective surrogate for an aldol condensation. Journal of the American Chemical Society. 131: 420-1. PMID 19099475 DOI: 10.1021/ja8077686  1
2008 McCauley JA, Rudd MT, Nguyen KT, McIntyre CJ, Romano JJ, Bush KJ, Varga SL, Ross CW, Carroll SS, DiMuzio J, Stahlhut MW, Olsen DB, Lyle TA, Vacca JP, Liverton NJ. Bismacrocyclic inhibitors of hepatitis C NS3/4a protease. Angewandte Chemie (International Ed. in English). 47: 9104-7. PMID 18925594 DOI: 10.1002/anie.200803298  1
2008 Liverton NJ, Holloway MK, McCauley JA, Rudd MT, Butcher JW, Carroll SS, DiMuzio J, Fandozzi C, Gilbert KF, Mao SS, McIntyre CJ, Nguyen KT, Romano JJ, Stahlhut M, Wan BL, et al. Molecular modeling based approach to potent P2-P4 macrocyclic inhibitors of hepatitis C NS3/4A protease. Journal of the American Chemical Society. 130: 4607-9. PMID 18338894 DOI: 10.1021/ja711120r  1
2005 Trost BM, Frederiksen MU, Rudd MT. Ruthenium-catalyzed reactions--a treasure trove of atom-economic transformations. Angewandte Chemie (International Ed. in English). 44: 6630-66. PMID 16206300 DOI: 10.1002/chin.200603257  1
2005 Rudd MT, McCauley JA. Positive allosteric modulators of the metabotropic glutamate receptor subtype 2 (mGluR2). Current Topics in Medicinal Chemistry. 5: 869-84. PMID 16178732 DOI: 10.2174/1568026054750281  1
2005 Trost BM, Rudd MT. Ruthenium-catalyzed cycloisomerizations of diynols. Journal of the American Chemical Society. 127: 4763-76. PMID 15796542 DOI: 10.1002/chin.200533045  1
2005 Ramachandran PV, Rudd MT, Reddy MVR. Stereoselective synthesis of hex-2-(E)-en-4-yn-1,6-dioates and E,Z-muconic acid diesters via organo-catalyzed self-coupling of propiolates Tetrahedron Letters. 46: 2547-2549. DOI: 10.1002/chin.200531071  1
2004 Trost BM, Rudd MT, Costa MG, Lee PI, Pomerantz AE. Regioselectivity control in a ruthenium-catalyzed cycloisomerization of diyne-ols. Organic Letters. 6: 4235-8. PMID 15524451 DOI: 10.1021/ol048351w  1
2003 Ramachandran PV, Rudd MT, Burghardt TE, Ram Reddy MV. Vinylalumination for the synthesis of functionalized allyl alcohols, vinylepoxides, and alpha-alkylidene-beta-hydroxy-gamma-lactones. The Journal of Organic Chemistry. 68: 9310-6. PMID 14629151 DOI: 10.1021/jo034954u  1
2003 Trost BM, Rudd MT. Chemoselectivity of the ruthenium-catalyzed hydrative diyne cyclization: total synthesis of (+)-cylindricine C, D, and E. Organic Letters. 5: 4599-602. PMID 14627393 DOI: 10.1021/ol035752n  1
2003 Trost BM, Rudd MT. A mechanistic dichotomy in ruthenium-catalyzed propargyl alcohol reactivity: a novel hydrative diyne cyclization. Journal of the American Chemical Society. 125: 11516-7. PMID 13129352 DOI: 10.1002/chin.200405040  1
2003 Trost BM, Rudd MT. Ruthenium-catalyzed alkyne-propargyl alcohol addition. An asymmetric total synthesis of (+)-alpha-kainic acid. Organic Letters. 5: 1467-70. PMID 12713300 DOI: 10.1021/ol034241y  1
2002 Ram Reddy MV, Rudd MT, Ramachandran PV. Study of fluorocarbonyls for the Baylis-Hillman reaction. The Journal of Organic Chemistry. 67: 5382-5. PMID 12126433 DOI: 10.1021/jo025591l  1
2002 Trost BM, Rudd MT. An unusual ruthenium-catalyzed cycloisomerization of alkynes and propargyl alcohols. Journal of the American Chemical Society. 124: 4178-9. PMID 11960424 DOI: 10.1021/ja012672a  1
2001 Trost BM, Rudd MT. An unusual ruthenium-catalyzed dimerization of propargyl alcohols. Journal of the American Chemical Society. 123: 8862-3. PMID 11535098 DOI: 10.1021/ja0111636  1
2001 Ramachandran PV, Reddy MVR, Rudd MT. Carbonyl and olefin reactivities for the Baylis-Hillman reaction of fluorocarbonyls Chemical Communications. 757-758.  1
1999 Ramachandran PV, Rudd MT, Reddy MVR. 1,4-diazabicyclo[2.2.2]octane-catalyzed self- and cross- condensation of α-acetylenic ketones Tetrahedron Letters. 40: 3819-3822. DOI: 10.1016/S0040-4039(99)00630-9  1
1999 Ramachandran PV, Reddy MVR, Rudd MT. Vinylalumination of activated carbonyl compounds Tetrahedron Letters. 40: 627-630. DOI: 10.1016/S0040-4039(98)02504-0  1
1999 Ramachandran PV, Reddy MVR, Rudd MT. Studies toward the syntheses of functionalized, fluorinated allyl alcohols Acs Symposium Series. 746: 117-126.  1
1999 Ramachandran PV, Reddy MVR, Rudd MT. An improved vinylalumination procedure replacing HMPA with NMO for the hydroalumination of α-acetylenic esters and ketones Chemical Communications. 1979-1980.  1
1998 Ramachandran PV, Reddy MVR, Rudd MT, De Alaniz JR. Vinylalumination of fluoro-carbonyl compounds Tetrahedron Letters. 39: 8791-8794.  1
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