Michael Thomas Rudd - Publications

Affiliations: 
1999-2005 Chemistry Stanford University, Palo Alto, CA 

15/58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Trost BM, Maulide N, Rudd MT. Ruthenium-catalyzed cross-coupling of tertiary propargyl alcohols with omega-alkynenitriles: a regio- and stereoselective surrogate for an aldol condensation. Journal of the American Chemical Society. 131: 420-1. PMID 19099475 DOI: 10.1021/Ja8077686  0.6
2009 Trost BM, Maulide N, Rudd MT. ChemInform Abstract: Ruthenium-Catalyzed Cross-Coupling of Tertiary Propargyl Alcohols with ω-Alkynenitriles: A Regio- and Stereoselective Surrogate for an Aldol Condensation. Cheminform. 40. DOI: 10.1002/chin.200921048  0.633
2005 Trost BM, Frederiksen MU, Rudd MT. Ruthenium-catalyzed reactions--a treasure trove of atom-economic transformations. Angewandte Chemie (International Ed. in English). 44: 6630-66. PMID 16206300 DOI: 10.1002/Anie.200500136  0.421
2005 Trost BM, Rudd MT. Ruthenium-catalyzed cycloisomerizations of diynols. Journal of the American Chemical Society. 127: 4763-76. PMID 15796542 DOI: 10.1021/Ja043097O  0.52
2005 Trost BM, Frederiksen MU, Rudd MT. Ruthenium-katalysierte Reaktionen - eine Schatzkiste für atomökonomische Umwandlungen Angewandte Chemie. 117: 6788-6825. DOI: 10.1002/Ange.200500136  0.393
2004 Trost BM, Rudd MT, Costa MG, Lee PI, Pomerantz AE. Regioselectivity control in a ruthenium-catalyzed cycloisomerization of diyne-ols. Organic Letters. 6: 4235-8. PMID 15524451 DOI: 10.1021/Ol048351W  0.573
2004 Ramachandran PV, Rudd MT, Burghardt TE, Reddy MVR. Vinylalumination for the Synthesis of Functionalized Allyl Alcohols, Vinylepoxides, and α-Alkylidene-β-hydroxy-γ-lactones. Cheminform. 35. DOI: 10.1002/chin.200414063  0.355
2003 Trost BM, Rudd MT. Chemoselectivity of the ruthenium-catalyzed hydrative diyne cyclization: total synthesis of (+)-cylindricine C, D, and E. Organic Letters. 5: 4599-602. PMID 14627393 DOI: 10.1021/Ol035752N  0.437
2003 Trost BM, Rudd MT. A mechanistic dichotomy in ruthenium-catalyzed propargyl alcohol reactivity: a novel hydrative diyne cyclization. Journal of the American Chemical Society. 125: 11516-7. PMID 13129352 DOI: 10.1021/Ja036410F  0.585
2003 Trost BM, Rudd MT. Ruthenium-catalyzed alkyne-propargyl alcohol addition. An asymmetric total synthesis of (+)-alpha-kainic acid. Organic Letters. 5: 1467-70. PMID 12713300 DOI: 10.1021/Ol034241Y  0.552
2002 Ram Reddy MV, Rudd MT, Ramachandran PV. Study of fluorocarbonyls for the Baylis-Hillman reaction. The Journal of Organic Chemistry. 67: 5382-5. PMID 12126433 DOI: 10.1021/jo025591l  0.328
2002 Trost BM, Rudd MT. An unusual ruthenium-catalyzed cycloisomerization of alkynes and propargyl alcohols. Journal of the American Chemical Society. 124: 4178-9. PMID 11960424 DOI: 10.1021/Ja012672A  0.638
2001 Trost BM, Rudd MT. An unusual ruthenium-catalyzed dimerization of propargyl alcohols. Journal of the American Chemical Society. 123: 8862-3. PMID 11535098 DOI: 10.1021/Ja0111636  0.555
2001 Ramachandran PV, Reddy MVR, Rudd MT. Carbonyl and olefin reactivities for the Baylis-Hillman reaction of fluorocarbonyls Chemical Communications. 757-758.  0.312
1999 Ramachandran PV, Reddy MVR, Rudd MT. Studies toward the syntheses of functionalized, fluorinated allyl alcohols Acs Symposium Series. 746: 117-126.  0.491
Low-probability matches (unlikely to be authored by this person)
2003 Ramachandran PV, Rudd MT, Burghardt TE, Ram Reddy MV. Vinylalumination for the synthesis of functionalized allyl alcohols, vinylepoxides, and alpha-alkylidene-beta-hydroxy-gamma-lactones. The Journal of Organic Chemistry. 68: 9310-6. PMID 14629151 DOI: 10.1021/jo034954u  0.3
2005 Ramachandran PV, Rudd MT, Reddy MVR. Stereoselective synthesis of hex-2-(E)-en-4-yn-1,6-dioates and E,Z-muconic acid diesters via organo-catalyzed self-coupling of propiolates Tetrahedron Letters. 46: 2547-2549. DOI: 10.1002/chin.200531071  0.219
1999 Ramachandran PV, Rudd MT, Reddy MVR. 1,4-diazabicyclo[2.2.2]octane-catalyzed self- and cross- condensation of α-acetylenic ketones Tetrahedron Letters. 40: 3819-3822. DOI: 10.1016/S0040-4039(99)00630-9  0.2
1999 Ramachandran PV, Reddy MVR, Rudd MT. An improved vinylalumination procedure replacing HMPA with NMO for the hydroalumination of α-acetylenic esters and ketones Chemical Communications. 1979-1980.  0.12
2017 Zhang H, Han GW, Batyuk A, Ishchenko A, White KL, Patel N, Sadybekov A, Zamlynny B, Rudd MT, Hollenstein K, Tolstikova A, White TA, Hunter MS, Weierstall U, Liu W, et al. Structural basis for selectivity and diversity in angiotensin II receptors. Nature. PMID 28379944 DOI: 10.1038/Nature22035  0.085
2015 Rudd MT, Butcher JW, Nguyen KT, McIntyre CJ, Romano JJ, Gilbert KF, Bush KJ, Liverton NJ, Holloway MK, Harper S, Ferrara M, DiFilippo M, Summa V, Swestock J, Fritzen J, et al. P2-quinazolinones and bis-macrocycles as new templates for next-generation hepatitis C virus NS3/4a protease inhibitors: discovery of MK-2748 and MK-6325. Chemmedchem. 10: 727-35. PMID 25759009 DOI: 10.1002/cmdc.201402558  0.079
2012 Rudd MT, McCauley JA, Romano JJ, Butcher JW, Bush K, McIntyre CJ, Nguyen KT, Gilbert KF, Lyle TA, Holloway MK, Wan BL, Vacca JP, Summa V, Harper S, Rowley M, et al. Development of potent macrocyclic inhibitors of genotype 3a HCV NS3/4A protease. Bioorganic & Medicinal Chemistry Letters. 22: 7201-6. PMID 23021993 DOI: 10.1016/j.bmcl.2012.08.106  0.073
2011 Rudd MT, McCauley JA, Butcher JW, Romano JJ, McIntyre CJ, Nguyen KT, Gilbert KF, Bush KJ, Holloway MK, Swestock J, Wan BL, Carroll SS, DiMuzio JM, Graham DJ, Ludmerer SW, et al. Discovery of MK-1220: A Macrocyclic Inhibitor of Hepatitis C Virus NS3/4A Protease with Improved Preclinical Plasma Exposure. Acs Medicinal Chemistry Letters. 2: 207-12. PMID 24900304 DOI: 10.1021/ml1002426  0.069
1998 Ramachandran PV, Reddy MVR, Rudd MT, De Alaniz JR. Vinylalumination of fluoro-carbonyl compounds Tetrahedron Letters. 39: 8791-8794.  0.063
2010 McCauley JA, McIntyre CJ, Rudd MT, Nguyen KT, Romano JJ, Butcher JW, Gilbert KF, Bush KJ, Holloway MK, Swestock J, Wan BL, Carroll SS, DiMuzio JM, Graham DJ, Ludmerer SW, et al. Discovery of vaniprevir (MK-7009), a macrocyclic hepatitis C virus NS3/4a protease inhibitor. Journal of Medicinal Chemistry. 53: 2443-63. PMID 20163176 DOI: 10.1021/jm9015526  0.06
2023 Rudd MT, Manley PJ, Hanney B, Meng Z, Shu Y, de Leon P, Frie JL, Han Y, Wai JM, Yang ZQ, Perkins JJ, Hurzy DM, Manikowski JJ, Zhu H, Bungard CJ, et al. Discovery of MK-8768, a Potent and Selective mGluR2 Negative Allosteric Modulator. Acs Medicinal Chemistry Letters. 14: 1088-1094. PMID 37583812 DOI: 10.1021/acsmedchemlett.3c00210  0.057
2004 Liew V, Rudd M, Martin A, Pegg S. Complex scalp defects from cicatricial pemphigoid and ionizing radiation. Burns : Journal of the International Society For Burn Injuries. 30: 495-8. PMID 15225920 DOI: 10.1016/j.burns.2003.12.017  0.056
2016 McCauley JA, Rudd MT. Hepatitis C virus NS3/4a protease inhibitors. Current Opinion in Pharmacology. 30: 84-92. PMID 27544488 DOI: 10.1016/j.coph.2016.07.015  0.056
2005 Rudd MT, McCauley JA. Positive allosteric modulators of the metabotropic glutamate receptor subtype 2 (mGluR2). Current Topics in Medicinal Chemistry. 5: 869-84. PMID 16178732 DOI: 10.2174/1568026054750281  0.055
2012 Harper S, McCauley JA, Rudd MT, Ferrara M, DiFilippo M, Crescenzi B, Koch U, Petrocchi A, Holloway MK, Butcher JW, Romano JJ, Bush KJ, Gilbert KF, McIntyre CJ, Nguyen KT, et al. Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor. Acs Medicinal Chemistry Letters. 3: 332-6. PMID 24900473 DOI: 10.1021/ml300017p  0.054
2014 Shah U, Jayne C, Chackalamannil S, Velázquez F, Guo Z, Buevich A, Howe JA, Chase R, Soriano A, Agrawal S, Rudd MT, McCauley JA, Liverton NJ, Romano J, Bush K, et al. Novel Quinoline-Based P2-P4 Macrocyclic Derivatives As Pan-Genotypic HCV NS3/4a Protease Inhibitors. Acs Medicinal Chemistry Letters. 5: 264-9. PMID 24900818 DOI: 10.1021/ml400466p  0.053
1999 Ramachandran PV, Reddy MVR, Rudd MT. Vinylalumination of activated carbonyl compounds Tetrahedron Letters. 40: 627-630. DOI: 10.1016/S0040-4039(98)02504-0  0.052
2020 Tong L, Li W, Lo MM, Gao X, Wai JM, Rudd MT, Tellers DM, Joshi A, Zeng Z, Miller P, Salinas C, Riffel K, Haley HD, Purcell M, Holahan M, et al. Discovery of [11C]MK-6884: A Positron Emission Tomography (PET) Imaging Agent for the Study of M4 Muscarinic Receptor Positive Allosteric Modulators (PAMs) in Neurodegenerative Diseases. Journal of Medicinal Chemistry. PMID 32101422 DOI: 10.1021/Acs.Jmedchem.9B01406  0.051
2012 Rudd MT, McIntyre CJ, Romano JJ, Butcher JW, Holloway MK, Bush K, Nguyen KT, Gilbert KF, Lyle TA, Liverton NJ, Wan BL, Summa V, Harper S, Rowley M, Vacca JP, et al. Development of macrocyclic inhibitors of HCV NS3/4A protease with cyclic constrained P2-P4 linkers. Bioorganic & Medicinal Chemistry Letters. 22: 7207-13. PMID 23084906 DOI: 10.1016/j.bmcl.2012.09.061  0.051
2014 Stachel SJ, Sanders JM, Henze DA, Rudd MT, Su HP, Li Y, Nanda KK, Egbertson MS, Manley PJ, Jones KL, Brnardic EJ, Green A, Grobler JA, Hanney B, Leitl M, et al. Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic pain. Journal of Medicinal Chemistry. 57: 5800-16. PMID 24914455 DOI: 10.1021/Jm5006429  0.046
2008 Boonyaratanakornkit V, Bi Y, Rudd M, Edwards DP. The role and mechanism of progesterone receptor activation of extra-nuclear signaling pathways in regulating gene transcription and cell cycle progression. Steroids. 73: 922-8. PMID 18321550 DOI: 10.1016/J.Steroids.2008.01.010  0.045
2016 Stachel SJ, Zerbinatti C, Rudd MT, Cosden M, Suon S, Nanda KK, Wessner K, Dimuzio JM, Maxwell J, Wu Z, Uslaner JM, Michener MS, Szczerba P, Brnardic E, Rada V, et al. Identification and In Vivo Evaluation of Liver X Receptor β (LXRβ) Selective Agonists for the Potential Treatment of Alzheimer's Disease. Journal of Medicinal Chemistry. PMID 27011007 DOI: 10.1021/Acs.Jmedchem.6B00176  0.044
2015 Solly K, Klein R, Rudd M, Holloway MK, Johnson EN, Henze D, Finley MF. High-Throughput Screen of GluK1 Receptor Identifies Selective Inhibitors with a Variety of Kinetic Profiles Using Fluorescence and Electrophysiology Assays. Journal of Biomolecular Screening. 20: 708-19. PMID 25700884 DOI: 10.1177/1087057115570580  0.043
2012 Summa V, Ludmerer SW, McCauley JA, Fandozzi C, Burlein C, Claudio G, Coleman PJ, Dimuzio JM, Ferrara M, Di Filippo M, Gates AT, Graham DJ, Harper S, Hazuda DJ, Huang Q, ... ... Rudd MT, et al. MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants. Antimicrobial Agents and Chemotherapy. 56: 4161-7. PMID 22615282 DOI: 10.1128/AAC.00324-12  0.04
2008 Liverton NJ, Holloway MK, McCauley JA, Rudd MT, Butcher JW, Carroll SS, DiMuzio J, Fandozzi C, Gilbert KF, Mao SS, McIntyre CJ, Nguyen KT, Romano JJ, Stahlhut M, Wan BL, et al. Molecular modeling based approach to potent P2-P4 macrocyclic inhibitors of hepatitis C NS3/4A protease. Journal of the American Chemical Society. 130: 4607-9. PMID 18338894 DOI: 10.1021/ja711120r  0.039
2013 Suyapto DR, Greenwood JE, Rudd M. Burns sustained whilst priming the carburetor: an Australian perspective. Journal of Burn Care & Research : Official Publication of the American Burn Association. 33: 634-7. PMID 22274631 DOI: 10.1097/BCR.0b013e31824799b8  0.034
2021 Hong C, Byrne NJ, Zamlynny B, Tummala S, Xiao L, Shipman JM, Partridge AT, Minnick C, Breslin MJ, Rudd MT, Stachel SJ, Rada VL, Kern JC, Armacost KA, Hollingsworth SA, et al. Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation. Nature Communications. 12: 815. PMID 33547286 DOI: 10.1038/s41467-021-21087-6  0.034
2016 Donovan ML, Muller MJ, Simpson C, Rudd M, Paratz J. Interim pressure garment therapy (4-6 mmHg) and its effect on donor site healing in burn patients: study protocol for a randomised controlled trial. Trials. 17: 214. PMID 27113487 DOI: 10.1186/s13063-016-1329-x  0.033
2008 McCauley JA, Rudd MT, Nguyen KT, McIntyre CJ, Romano JJ, Bush KJ, Varga SL, Ross CW, Carroll SS, DiMuzio J, Stahlhut MW, Olsen DB, Lyle TA, Vacca JP, Liverton NJ. Bismacrocyclic inhibitors of hepatitis C NS3/4a protease. Angewandte Chemie (International Ed. in English). 47: 9104-7. PMID 18925594 DOI: 10.1002/anie.200803298  0.03
2010 Liverton NJ, Carroll SS, Dimuzio J, Fandozzi C, Graham DJ, Hazuda D, Holloway MK, Ludmerer SW, McCauley JA, McIntyre CJ, Olsen DB, Rudd MT, Stahlhut M, Vacca JP. MK-7009, a potent and selective inhibitor of hepatitis C virus NS3/4A protease. Antimicrobial Agents and Chemotherapy. 54: 305-11. PMID 19841155 DOI: 10.1128/AAC.00677-09  0.028
2022 Boots R, Xue G, Tromp D, Rawashdeh O, Bellapart J, Townsend S, Rudd M, Winter C, Mitchell G, Garner N, Clement P, Karamujic N, Zappala C. Circadian Rhythmicity of Vital Signs at Intensive Care Unit Discharge and Outcome of Traumatic Brain Injury. American Journal of Critical Care : An Official Publication, American Association of Critical-Care Nurses. 31: 472-482. PMID 36316179 DOI: 10.4037/ajcc2022821  0.027
2020 Bodnar D, Parker L, Rashford S, Rudd M. The Pre-Hospital Initial Fluid Therapy Estimate in Early Nasty Burns (PHIFTEEN B, 15-B) Guideline applied to a retrospective cohort of Intensive Care Unit patients with major burns. Burns : Journal of the International Society For Burn Injuries. PMID 33183830 DOI: 10.1016/j.burns.2020.03.003  0.026
2012 Lewis PA, Wright K, Webster A, Steer M, Rudd M, Doubrovsky A, Gardner G. A randomized controlled pilot study comparing aqueous cream with a beeswax and herbal oil cream in the provision of relief from postburn pruritus. Journal of Burn Care & Research : Official Publication of the American Burn Association. 33: e195-200. PMID 22665131 DOI: 10.1097/BCR.0b013e31825042e2  0.024
2012 Adnan S, Paterson DL, Lipman J, Kumar S, Li J, Rudd M, Roberts JA. Pharmacokinetics of beta-lactam antibiotics in patients with intra-abdominal disease: a structured review. Surgical Infections. 13: 9-17. PMID 22316144 DOI: 10.1089/sur.2011.046  0.024
2022 Li W, Wang Y, Lohith TG, Zeng Z, Tong L, Mazzola R, Riffel K, Miller P, Purcell M, Holahan M, Haley H, Gantert L, Hesk D, Ren S, Morrow J, ... ... Rudd MT, et al. The PET tracer [C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer's disease. Science Translational Medicine. 14: eabg3684. PMID 35020407 DOI: 10.1126/scitranslmed.abg3684  0.022
2012 Patel BM, Paratz J, See NC, Muller MJ, Rudd M, Paterson D, Briscoe SE, Ungerer J, McWhinney BC, Lipman J, Roberts JA. Therapeutic drug monitoring of beta-lactam antibiotics in burns patients--a one-year prospective study. Therapeutic Drug Monitoring. 34: 160-4. PMID 22406650 DOI: 10.1097/FTD.0b013e31824981a6  0.018
2007 Dalley AJ, Lipman J, Venkatesh B, Rudd M, Roberts MS, Cross SE. Inadequate antimicrobial prophylaxis during surgery: a study of beta-lactam levels during burn debridement. The Journal of Antimicrobial Chemotherapy. 60: 166-9. PMID 17504805 DOI: 10.1093/jac/dkm128  0.018
2005 Atkinson JA, McKenna KT, Barnett AG, McGrath DJ, Rudd M. A randomized, controlled trial to determine the efficacy of paper tape in preventing hypertrophic scar formation in surgical incisions that traverse Langer's skin tension lines. Plastic and Reconstructive Surgery. 116: 1648-56; discussion . PMID 16267427 DOI: 10.1097/01.prs.0000187147.73963.a5  0.014
2020 Aston S, Denisova K, Hurlbert A, Olkkonen M, Pearce B, Rudd M, Werner A, Xiao B. Exploring the Determinants of Color Perception Using #Thedress and Its Variants: The Role of Spatio-Chromatic Context, Chromatic Illumination, and Material-Light Interaction. Perception. 49: 1235-1251. PMID 33183137 DOI: 10.1177/0301006620963808  0.01
2013 Adnan S, Li JX, Wallis SC, Rudd M, Jarrett P, Paterson DL, Lipman J, Udy AA, Roberts JA. Pharmacokinetics of meropenem and piperacillin in critically ill patients with indwelling surgical drains. International Journal of Antimicrobial Agents. 42: 90-3. PMID 23590897 DOI: 10.1016/j.ijantimicag.2013.02.023  0.01
2012 Patel BM, Paratz JD, Mallet A, Lipman J, Rudd M, Muller MJ, Paterson DL, Roberts JA. Characteristics of bloodstream infections in burn patients: An 11-year retrospective study. Burns : Journal of the International Society For Burn Injuries. 38: 685-90. PMID 22348799 DOI: 10.1016/j.burns.2011.12.018  0.01
2009 Dalley AJ, Deans R, Lipman J, Venkatesh B, Rudd M, Roberts MS, Cross SE. Unbound cephalothin pharmacokinetics in adult burn patients are related to the elapsed time after injury. Antimicrobial Agents and Chemotherapy. 53: 5303-5. PMID 19752272 DOI: 10.1128/AAC.01600-08  0.01
2009 Dalley AJ, Lipman J, Deans R, Venkatesh B, Rudd M, Roberts MS, Cross SE. Tissue accumulation of cephalothin in burns: a comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers. Antimicrobial Agents and Chemotherapy. 53: 210-5. PMID 18955521 DOI: 10.1128/AAC.00718-08  0.01
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