| Year |
Citation |
Score |
| 2023 |
Lu Y, You L, Li L, Kilgore JA, Liu S, Wang X, Dai Y, Wei Q, Shi H, Han L, Sun L, Chen ZJ, Zhang X, Williams NS, Chen C. Orthogonal Hydroxyl Functionalization of cGAMP Confers Metabolic Stability and Enables Antibody Conjugation. Acs Central Science. 9: 2298-2305. PMID 38161369 DOI: 10.1021/acscentsci.3c01122 |
0.422 |
|
| 2023 |
Lu Y, Chen C. Exceptional reactivity of the bridgehead amine on bicyclo[1.1.1]pentane. Arkivoc : Free Online Journal of Organic Chemistry. 2023. PMID 37786812 DOI: 10.24820/ark.5550190.p012.003 |
0.428 |
|
| 2023 |
Wang B, Lu Y, Cha L, Chen TY, Palacios PM, Li L, Guo Y, Chang WC, Chen C. Repurposing Iron- and 2-Oxoglutarate-Dependent Oxygenases to Catalyze Olefin Hydration. Angewandte Chemie (International Ed. in English). e202311099. PMID 37639670 DOI: 10.1002/anie.202311099 |
0.366 |
|
| 2022 |
Lu Y, You L, Chen C. A phosphine-based redox method for direct conjugation of disulfides. Chemical Communications (Cambridge, England). 58: 12439-12442. PMID 36278800 DOI: 10.1039/d2cc04967h |
0.384 |
|
| 2021 |
Deng Y, You L, Lu Y, Han S, Wang J, Vicas N, Chen C, Ye J. Identification of TRAMs as Sphingolipid-Binding Proteins Using a Photoactivatable and Clickable Short Chain Ceramide Analog. The Journal of Biological Chemistry. 101415. PMID 34793833 DOI: 10.1016/j.jbc.2021.101415 |
0.383 |
|
| 2020 |
Johnston AN, Ma Y, Liu H, Liu S, Hanna-Addams S, Chen S, Chen C, Wang Z. Necroptosis-blocking compound NBC1 targets heat shock protein 70 to inhibit MLKL polymerization and necroptosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 32156734 DOI: 10.1073/Pnas.1916503117 |
0.304 |
|
| 2019 |
Wang S, Han L, Han J, Li P, Ding Q, Zhang QJ, Liu ZP, Chen C, Yu Y. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nature Chemical Biology. PMID 31659317 DOI: 10.1038/S41589-019-0379-2 |
0.305 |
|
| 2018 |
You L, Chen C. Rapid access to the core skeleton of the [3 + 2]-type dimeric pyrrole-imidazole alkaloids by triplet ketone-mediated C-H functionalization. Tetrahedron. 74: 769-772. PMID 29622843 DOI: 10.1016/J.Tet.2017.12.027 |
0.397 |
|
| 2018 |
Ma Z, Chen C. Natural products as inspiration for the development of new synthetic methods. Journal of the Chinese Chemical Society. Zhongguo Hua Xue Hui (Taipei, Taiwan). 65: 43-59. PMID 29430058 DOI: 10.1002/Jccs.201700134 |
0.307 |
|
| 2017 |
Han L, Xia J, You L, Chen C. Ketone-catalyzed photochemical C(sp(3))-H chlorination. Tetrahedron. 73: 3696-3701. PMID 28717256 DOI: 10.1016/J.Tet.2017.05.008 |
0.338 |
|
| 2016 |
Ma Z, You L, Chen C. Stereocontrolled Formation of a [4.4]-Heterospiro Ring System with Unexpected Inversion of Configuration at the Spirocenter. The Journal of Organic Chemistry. PMID 27933858 DOI: 10.1021/Acs.Joc.6B02266 |
0.407 |
|
| 2016 |
You L, Zhang C, Yarravarapu N, Morlock L, Wang X, Zhang L, Williams NS, Lum L, Chen C. Development of a triazole class of highly potent Porcn inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27876319 DOI: 10.1016/J.Bmcl.2016.11.012 |
0.345 |
|
| 2016 |
Wang X, Ma Z, Lu J, Tan X, Chen C. Correction to "Asymmetric Synthesis of Ageliferin". Journal of the American Chemical Society. 138: 14504. PMID 27802603 DOI: 10.1021/Jacs.6B09696 |
0.402 |
|
| 2016 |
Zhang C, You L, Chen C. Palladium-Catalyzed C-H Arylation of 1,2,3-Triazoles. Molecules (Basel, Switzerland). 21. PMID 27669198 DOI: 10.3390/Molecules21101268 |
0.366 |
|
| 2016 |
Chen C. The past, present, and future of the Yang reaction. Organic & Biomolecular Chemistry. PMID 27517138 DOI: 10.1039/C6Ob01214K |
0.334 |
|
| 2016 |
Ma Z, Wang X, Ma Y, Chen C. Asymmetric Synthesis of Axinellamines A and B. Angewandte Chemie (International Ed. in English). 55: 4763-4766. PMID 27037993 DOI: 10.1002/Anie.201600007 |
0.406 |
|
| 2015 |
Wang X, Gao Y, Ma Z, Rodriguez RA, Yu ZX, Chen C. Syntheses of Sceptrins and Nakamuric Acid and Insights into the Biosyntheses of Pyrrole-Imidazole Dimers. Organic Chemistry Frontiers : An International Journal of Organic Chemistry / Royal Society of Chemistry. 2: 978-984. PMID 26328059 DOI: 10.1039/C5Qo00165J |
0.397 |
|
| 2015 |
Lum L, Chen C. Chemical Disruption of Wnt-dependent Cell Fate Decision-making Mechanisms in Cancer and Regenerative Medicine. Current Medicinal Chemistry. 22: 4091-4103. PMID 26310918 DOI: 10.2174/0929867322666150827094015 |
0.302 |
|
| 2015 |
Ma Z, Wang X, Wang X, Rodriguez RA, Moore CE, Gao S, Tan X, Ma Y, Rheingold AL, Baran PS, Chen C. ORGANIC SYNTHESIS. Response to Comment on "Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence". Science (New York, N.Y.). 349: 149. PMID 26160939 DOI: 10.1126/Science.Aaa9626 |
0.331 |
|
| 2015 |
Shi H, De S, Wang Q, Gao S, Wang X, Chen C. Construction of the 5,6,7-tricyclic skeleton of lancifodilactone F. Tetrahedron Letters. 56: 3225-3227. PMID 26097263 DOI: 10.1016/J.Tetlet.2014.12.054 |
0.374 |
|
| 2015 |
Wang X, Chen C. An approach for the synthesis of nakamuric acid. Tetrahedron. 71: 3690-3693. PMID 25983349 DOI: 10.1016/J.Tet.2014.10.027 |
0.358 |
|
| 2015 |
Ma Y, De S, Chen C. Syntheses of Cyclic Guanidine-Containing Natural Products. Tetrahedron. 71: 1145-1173. PMID 25684829 DOI: 10.1016/J.Tet.2014.11.056 |
0.328 |
|
| 2014 |
Ma Z, Wang X, Wang X, Rodriguez RA, Moore CE, Gao S, Tan X, Ma Y, Rheingold AL, Baran PS, Chen C. Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence. Science (New York, N.Y.). 346: 219-24. PMID 25301624 DOI: 10.1126/Science.1255677 |
0.416 |
|
| 2014 |
Xia JB, Ma Y, Chen C. Vanadium-Catalyzed C(sp(3))-H Fluorination Reactions. Organic Chemistry Frontiers : An International Journal of Organic Chemistry / Royal Society of Chemistry. 1: 468-472. PMID 24976971 DOI: 10.1039/C4Qo00057A |
0.354 |
|
| 2014 |
Wang X, Ma Z, Wang X, De S, Ma Y, Chen C. Dimeric pyrrole-imidazole alkaloids: synthetic approaches and biosynthetic hypotheses. Chemical Communications (Cambridge, England). 50: 8628-39. PMID 24828265 DOI: 10.1039/C4Cc02290D |
0.353 |
|
| 2014 |
Zhu C, Xia JB, Chen C. Vanadium-catalyzed oxidative Strecker reaction: α-C-H cyanation of para-methoxyphenyl (PMP)-protected primary amines. Tetrahedron Letters. 55. PMID 24415804 DOI: 10.1016/J.Tetlet.2013.11.012 |
0.336 |
|
| 2014 |
Zhu C, Xia JB, Chen C. A simple method for the electrophilic cyanation of secondary amines. Organic Letters. 16: 247-9. PMID 24313859 DOI: 10.1021/Ol403245R |
0.326 |
|
| 2013 |
Xia JB, Zhu C, Chen C. Visible light-promoted metal-free C-H activation: diarylketone-catalyzed selective benzylic mono- and difluorination. Journal of the American Chemical Society. 135: 17494-500. PMID 24180320 DOI: 10.1021/Ja410815U |
0.323 |
|
| 2013 |
Wang X, Moon J, Dodge ME, Pan X, Zhang L, Hanson JM, Tuladhar R, Ma Z, Shi H, Williams NS, Amatruda JF, Carroll TJ, Lum L, Chen C. The development of highly potent inhibitors for porcupine. Journal of Medicinal Chemistry. 56: 2700-4. PMID 23477365 DOI: 10.1021/Jm400159C |
0.323 |
|
| 2013 |
Wang X, Wang X, Tan X, Lu J, Cormier KW, Ma Z, Chen C. Correction to a biomimetic route for construction of the [4 + 2] and [3 + 2] core skeletons of dimeric pyrrole-imidazole alkaloids and asymmetric synthesis of ageliferins. Journal of the American Chemical Society. 135: 1163. PMID 23311687 DOI: 10.1021/Ja311681X |
0.4 |
|
| 2012 |
Wang X, Wang X, Tan X, Lu J, Cormier KW, Ma Z, Chen C. A biomimetic route for construction of the [4+2] and [3+2] core skeletons of dimeric pyrrole-imidazole alkaloids and asymmetric synthesis of ageliferins. Journal of the American Chemical Society. 134: 18834-42. PMID 23072663 DOI: 10.1021/Ja309172T |
0.437 |
|
| 2012 |
Dodge ME, Moon J, Tuladhar R, Lu J, Jacob LS, Zhang LS, Shi H, Wang X, Moro E, Mongera A, Argenton F, Karner CM, Carroll TJ, Chen C, Amatruda JF, et al. Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine. The Journal of Biological Chemistry. 287: 23246-54. PMID 22593577 DOI: 10.1074/Jbc.M112.372029 |
0.327 |
|
| 2011 |
Wang X, Ma Z, Lu J, Tan X, Chen C. Asymmetric synthesis of ageliferin. Journal of the American Chemical Society. 133: 15350-3. PMID 21888421 DOI: 10.1021/Ja207386Q |
0.434 |
|
| 2011 |
Ma Z, Lu J, Wang X, Chen C. Revisiting the Kinnel-Scheuer hypothesis for the biosynthesis of palau'amine. Chemical Communications (Cambridge, England). 47: 427-9. PMID 20848010 DOI: 10.1039/C0Cc02214D |
0.385 |
|
| 2011 |
Huang X-, Pan X-, Lee G-, Chen C. New Ligands for Catalytic Asymmetric NHK Allylation of Aldehydes Synfacts. 2011: 1209-1209. DOI: 10.1055/S-0031-1289178 |
0.3 |
|
| 2010 |
Karner CM, Merkel CE, Dodge M, Ma Z, Lu J, Chen C, Lum L, Carroll TJ. Tankyrase is necessary for canonical Wnt signaling during kidney development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 2014-23. PMID 20549720 DOI: 10.1002/Dvdy.22340 |
0.311 |
|
| 2010 |
Gao S, Wang Q, Huang LJ, Lum L, Chen C. Chemical and biological studies of nakiterpiosin and nakiterpiosinone. Journal of the American Chemical Society. 132: 371-83. PMID 20000429 DOI: 10.1021/Ja908626K |
0.404 |
|
| 2009 |
Lu J, Ma Z, Hsieh JC, Fan CW, Chen B, Longgood JC, Williams NS, Amatruda JF, Lum L, Chen C. Structure-activity relationship studies of small-molecule inhibitors of Wnt response. Bioorganic & Medicinal Chemistry Letters. 19: 3825-7. PMID 19410457 DOI: 10.1016/J.Bmcl.2009.04.040 |
0.319 |
|
| 2009 |
Chen B, Dodge ME, Tang W, Lu J, Ma Z, Fan CW, Wei S, Hao W, Kilgore J, Williams NS, Roth MG, Amatruda JF, Chen C, Lum L. Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nature Chemical Biology. 5: 100-7. PMID 19125156 DOI: 10.1038/Nchembio.137 |
0.316 |
|
| 2009 |
Gao S, Wang Q, Chen C. Synthesis and structure revision of nakiterpiosin. Journal of the American Chemical Society. 131: 1410-2. PMID 18998640 DOI: 10.1021/Ja808110D |
0.429 |
|
| 2009 |
Gao S, Wang Q, Chen C. Synthesis of Nakiterpiosin Synfacts. 2009: 703-703. DOI: 10.1055/S-0029-1217242 |
0.426 |
|
| 2008 |
Wang Q, Chen C. An approach to the core skeleton of lancifodilactone F. Organic Letters. 10: 1223-6. PMID 18303901 DOI: 10.1021/Ol800111J |
0.324 |
|
| 2008 |
Wang Q, Chen C. Nickel-catalyzed carbonylative Negishi cross-coupling reactions Tetrahedron Letters. 49: 2916-2921. DOI: 10.1016/J.Tetlet.2008.03.035 |
0.33 |
|
| 2007 |
Lu J, Tan X, Chen C. Palladium-catalyzed direct functionalization of imidazolinone: synthesis of dibromophakellstatin. Journal of the American Chemical Society. 129: 7768-9. PMID 17539649 DOI: 10.1021/Ja072844P |
0.349 |
|
| 2007 |
Lu J, Tan X, Chen C. Palladium-Catalyzed Direct Functionalization of Imidazolinone: Synthesis of Dibromophakellstatin [J. Am. Chem. Soc.2007,129, 7768−7769]. Journal of the American Chemical Society. 129: 14100-14100. DOI: 10.1021/Ja077266R |
0.362 |
|
| 2005 |
Chen C, Li X, Neumann CS, Lo MM, Schreiber SL. Convergent diversity-oriented synthesis of small-molecule hybrids. Angewandte Chemie (International Ed. in English). 44: 2249-52. PMID 15747386 DOI: 10.1002/Anie.200462798 |
0.474 |
|
| 2003 |
Chen C, Li X, Schreiber SL. Catalytic asymmetric [3+2] cycloaddition of azomethine ylides. Development of a versatile stepwise, three-component reaction for diversity-oriented synthesis. Journal of the American Chemical Society. 125: 10174-5. PMID 12926931 DOI: 10.1021/Ja036558Z |
0.522 |
|
| 2000 |
Chen C, Layton ME, Sheehan SM, Shair MD. Synthesis of (+)-CP-263,114 [20] Journal of the American Chemical Society. 122: 7424-7425. DOI: 10.1021/Ja001958X |
0.692 |
|
| 1999 |
Cheng WL, Shaw YJ, Yeh SM, Kanakamma PP, Chen YH, Chen C, Shieu JC, Yiin SJ, Lee GH, Wang Y, Luh TY. Chelation-assisted regioselective C-O bond cleavage reactions of acetals by Grignard reagents. A general procedure for the regioselective synthesis of protected polyols having one free hydroxy group Journal of Organic Chemistry. 64: 532-539. DOI: 10.1021/Jo981579A |
0.386 |
|
| 1998 |
Chen C, Layton ME, Shair MD. Stereospecific synthesis of the CP-263,114 core structure [13] Journal of the American Chemical Society. 120: 10784-10785. DOI: 10.1021/Ja982581M |
0.695 |
|
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