Edwin Thrower - Publications

Affiliations: 
1999-2002 Pharmacology Yale University, New Haven, CT 

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Orabi AI, Luo Y, Ahmad MU, Shah AU, Mannan Z, Wang D, Sarwar S, Muili KA, Shugrue C, Kolodecik TR, Singh VP, Lowe ME, Thrower E, Chen J, Husain SZ. IP3 receptor type 2 deficiency is associated with a secretory defect in the pancreatic acinar cell and an accumulation of zymogen granules. Plos One. 7: e48465. PMID 23185258 DOI: 10.1371/Journal.Pone.0048465  0.559
2011 Reed AM, Husain SZ, Thrower E, Alexandre M, Shah A, Gorelick FS, Nathanson MH. Low extracellular pH induces damage in the pancreatic acinar cell by enhancing calcium signaling. The Journal of Biological Chemistry. 286: 1919-26. PMID 21084290 DOI: 10.1074/Jbc.M110.158329  0.513
2009 Gorelick FS, Thrower E. The acinar cell and early pancreatitis responses. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 7: S10-4. PMID 19896090 DOI: 10.1016/J.Cgh.2009.07.036  0.379
2009 Husain S, Thrower E. Molecular and cellular regulation of pancreatic acinar cell function. Current Opinion in Gastroenterology. 25: 466-71. PMID 19571746 DOI: 10.1097/Mog.0B013E32832Ebfac  0.331
2006 Grant W, Shah A, Thrower E, Husain S. Caerulein-Induced Intracellular Pancreatic Zymogen Activation Is Dependent Upon Calcineurin Pancreas. 33: 464. DOI: 10.1097/00006676-200611000-00095  0.341
2003 Thrower EC, Choe CU, So SH, Jeon SH, Ehrlich BE, Yoo SH. A functional interaction between chromogranin B and the inositol 1,4,5-trisphosphate receptor/Ca2+ channel. The Journal of Biological Chemistry. 278: 49699-706. PMID 14506248 DOI: 10.1074/Jbc.M309307200  0.656
2003 Leite MF, Thrower EC, Echevarria W, Koulen P, Hirata K, Bennett AM, Ehrlich BE, Nathanson MH. Nuclear and cytosolic calcium are regulated independently. Proceedings of the National Academy of Sciences of the United States of America. 100: 2975-80. PMID 12606721 DOI: 10.1073/Pnas.0536590100  0.63
2002 Jiang QX, Thrower EC, Chester DW, Ehrlich BE, Sigworth FJ. Three-dimensional structure of the type 1 inositol 1,4,5-trisphosphate receptor at 24 A resolution. The Embo Journal. 21: 3575-81. PMID 12110570 DOI: 10.1093/Emboj/Cdf380  0.539
2002 Thrower EC, Park HY, So SH, Yoo SH, Ehrlich BE. Activation of the inositol 1,4,5-trisphosphate receptor by the calcium storage protein chromogranin A. The Journal of Biological Chemistry. 277: 15801-6. PMID 11842082 DOI: 10.1074/Jbc.M110139200  0.658
2001 Koulen P, Thrower EC. Pharmacological modulation of intracellular Ca(2+) channels at the single-channel level. Molecular Neurobiology. 24: 65-86. PMID 11831555 DOI: 10.1385/MN:24:1-3:065  0.425
2001 Thrower EC, Hagar RE, Ehrlich BE. Regulation of Ins(1,4,5)P3 receptor isoforms by endogenous modulators. Trends in Pharmacological Sciences. 22: 580-6. PMID 11698102 DOI: 10.1016/S0165-6147(00)01809-5  0.642
2000 Thrower EC, Mobasheri H, Dargan S, Marius P, Lea EJ, Dawson AP. Interaction of luminal calcium and cytosolic ATP in the control of type 1 inositol (1,4,5)-trisphosphate receptor channels. The Journal of Biological Chemistry. 275: 36049-55. PMID 10956640 DOI: 10.1074/jbc.M000970200  0.672
1999 Thrower EC. Measurement of Ca2+ flux through Ins(1,4,5)P3 receptor-Ca2+ channels in lipid bilayers ("dip-tip" and "Schindler" methodology). Methods in Molecular Biology (Clifton, N.J.). 114: 221-33. PMID 10081021 DOI: 10.1385/1-59259-250-3:221  0.519
1998 Thrower EC, Lea EJ, Dawson AP. The effects of free [Ca2+] on the cytosolic face of the inositol (1,4,5)-trisphosphate receptor at the single channel level. The Biochemical Journal. 330: 559-64. PMID 9461556  0.511
1996 Thrower EC, Duclohier H, Lea EJ, Molle G, Dawson AP. The inositol 1,4,5-trisphosphate-gated Ca2+ channel: effect of the protein thiol reagent thimerosal on channel activity. The Biochemical Journal. 318: 61-6. PMID 8761453  0.408
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