| Year |
Citation |
Score |
| 2022 |
Christensen TA, Lee KY, Gottlieb SZP, Carrier MB, Leconte AM. Mutant polymerases capable of 2' fluoro-modified nucleic acid synthesis and amplification with improved accuracy. Rsc Chemical Biology. 3: 1044-1051. PMID 35975008 DOI: 10.1039/d2cb00064d |
0.337 |
|
| 2020 |
Thompson A, Barrett S, Weiden A, Venkatesh A, Seto M, Gottlieb S, Leconte AM. Accurate and efficient one-pot reverse transcription and amplification of 2' fluoro-modified nucleic acids by commercial DNA polymerases. Biochemistry. PMID 32659079 DOI: 10.1021/Acs.Biochem.0C00494 |
0.463 |
|
| 2020 |
Thompson A, Barrett S, Weiden A, Leconte A. Reverse transcription and amplification of 2′F DNA by commercially available DNA polymerases The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00614 |
0.453 |
|
| 2020 |
Seto MK, Barrett SE, Weiden AG, Leconte AM. Characterization of Modified‐DNA Polymerase Fidelity The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00315 |
0.349 |
|
| 2017 |
Liu MD, Warner EA, Morrissey CE, Fick CW, Wu TS, Ornelas MY, Ochoa GV, Zhang B, Rathbun CM, Porterfield WB, Prescher JA, Leconte AM. Statistical Coupling Analysis-guided library design for discovery of mutant luciferases. Biochemistry. PMID 29224332 DOI: 10.1021/Acs.Biochem.7B01014 |
0.332 |
|
| 2017 |
Lewis EL, Leconte AM. DNA Polymerase Activity Assay Using Near-infrared Fluorescent Labeled DNA Visualized by Acrylamide Gel Electrophoresis. Journal of Visualized Experiments : Jove. PMID 29053685 DOI: 10.3791/56228 |
0.483 |
|
| 2017 |
Rosenblum SL, Weiden AG, Lewis EL, Ogonowsky AL, Chia HE, Barrett SE, Liu MD, Leconte AM. Design and discovery of new combinations of mutant DNA polymerases and modified DNA substrates. Chembiochem : a European Journal of Chemical Biology. PMID 28160372 DOI: 10.1002/Cbic.201600701 |
0.496 |
|
| 2015 |
Schultz HJ, Gochi AM, Chia HE, Ogonowsky AL, Chiang S, Filipovic N, Weiden AG, Hadley EE, Gabriel SE, Leconte AM. Taq DNA polymerase mutants and 2' modified sugar recognition. Biochemistry. PMID 26334839 DOI: 10.1021/Acs.Biochem.5B00689 |
0.479 |
|
| 2013 |
Dickinson BC, Leconte AM, Allen B, Esvelt KM, Liu DR. Experimental interrogation of the path dependence and stochasticity of protein evolution using phage-assisted continuous evolution Proceedings of the National Academy of Sciences of the United States of America. 110: 9007-9012. PMID 23674678 DOI: 10.1073/Pnas.1220670110 |
0.718 |
|
| 2013 |
Leconte AM, Dickinson BC, Yang DD, Chen IA, Allen B, Liu DR. A population-based experimental model for protein evolution: Effects of mutation rate and selection stringency on evolutionary outcomes Biochemistry. 52: 1490-1499. PMID 23360105 DOI: 10.1021/Bi3016185 |
0.664 |
|
| 2012 |
Dumelin CE, Chen Y, Leconte AM, Chen YG, Liu DR. Discovery and biological characterization of geranylated RNA in bacteria. Nature Chemical Biology. 8: 913-9. PMID 22983156 DOI: 10.1038/Nchembio.1070 |
0.537 |
|
| 2012 |
Duyzend MH, Clark CT, Simmons SL, Johnson WB, Larson AM, Leconte AM, Wills AW, Ginder-Vogel M, Wilhelm AK, Czechowicz JA, Alberg DG. Synthesis and evaluation of substrate analogue inhibitors of trypanothione reductase. Journal of Enzyme Inhibition and Medicinal Chemistry. 27: 784-94. PMID 22085139 DOI: 10.3109/14756366.2011.604319 |
0.678 |
|
| 2010 |
Leconte AM, Patel MP, Sass LE, McInerney P, Jarosz M, Kung L, Bowers JL, Buzby PR, Efcavitch JW, Romesberg FE. Directed evolution of DNA polymerases for next-generation sequencing. Angewandte Chemie (International Ed. in English). 49: 5921-4. PMID 20629059 DOI: 10.1002/Anie.201001607 |
0.642 |
|
| 2008 |
Hari Y, Hwang GT, Leconte AM, Joubert N, Hocek M, Romesberg FE. Optimization of the pyridyl nucleobase scaffold for polymerase recognition and unnatural base pair replication. Chembiochem : a European Journal of Chemical Biology. 9: 2796-9. PMID 19012285 DOI: 10.1002/Cbic.200800577 |
0.757 |
|
| 2008 |
Leconte AM, Hwang GT, Matsuda S, Capek P, Hari Y, Romesberg FE. Discovery, characterization, and optimization of an unnatural base pair for expansion of the genetic alphabet. Journal of the American Chemical Society. 130: 2336-43. PMID 18217762 DOI: 10.1021/Ja078223D |
0.726 |
|
| 2007 |
Hwang GT, Leconte AM, Romesberg FE. Polymerase recognition and stability of fluoro-substituted pyridone nucleobase analogues. Chembiochem : a European Journal of Chemical Biology. 8: 1606-11. PMID 17647205 DOI: 10.1002/Cbic.200700308 |
0.736 |
|
| 2007 |
Matsuda S, Leconte AM, Romesberg FE. Minor groove hydrogen bonds and the replication of unnatural base pairs. Journal of the American Chemical Society. 129: 5551-7. PMID 17411040 DOI: 10.1021/Ja068282B |
0.731 |
|
| 2006 |
Leconte AM, Romesberg FE. Chemical biology: a broader take on DNA. Nature. 444: 553-5. PMID 17136078 DOI: 10.1038/444553A |
0.661 |
|
| 2006 |
Kim Y, Leconte AM, Hari Y, Romesberg FE. Stability and polymerase recognition of pyridine nucleobase analogues: role of minor-groove H-bond acceptors. Angewandte Chemie (International Ed. in English). 45: 7809-12. PMID 17075934 DOI: 10.1002/Anie.200602579 |
0.533 |
|
| 2006 |
Leconte AM, Romesberg FE. Amplify this! DNA and RNA get a third base pair. Nature Methods. 3: 667-8. PMID 16929309 DOI: 10.1038/Nmeth0906-667 |
0.643 |
|
| 2006 |
Leconte AM, Matsuda S, Hwang GT, Romesberg FE. Efforts towards expansion of the genetic alphabet: pyridone and methyl pyridone nucleobases. Angewandte Chemie (International Ed. in English). 45: 4326-9. PMID 16733840 DOI: 10.1002/Anie.200601272 |
0.706 |
|
| 2006 |
Leconte AM, Matsuda S, Romesberg FE. An efficiently extended class of unnatural base pairs. Journal of the American Chemical Society. 128: 6780-1. PMID 16719445 DOI: 10.1021/Ja060853C |
0.751 |
|
| 2005 |
Leconte AM, Chen L, Romesberg FE. Polymerase evolution: efforts toward expansion of the genetic code. Journal of the American Chemical Society. 127: 12470-1. PMID 16144377 DOI: 10.1021/Ja053322H |
0.778 |
|
| 2005 |
Leconte AM, Romesberg FE. Efforts towards expansion of the genetic alphabet Collection of Czechoslovak Chemical Communications. 7: 77-84. DOI: 10.1135/Css200507077 |
0.697 |
|
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