R. Jeffrey Neitz - Publications

Affiliations: 
2003 University of Michigan, Ann Arbor, Ann Arbor, MI 

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Alverez C, Bulfer SL, Chakrasali R, Chimenti MS, Deshaies RJ, Green N, Kelly M, LaPorte MG, Lewis TS, Liang M, Moore WJ, Neitz RJ, Peshkov VA, Walters MA, Zhang F, et al. Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway Acs Medicinal Chemistry Letters. 7: 182-187. DOI: 10.1021/acsmedchemlett.5b00396  0.88
2015 Khare S, Roach SL, Barnes SW, Hoepfner D, Walker JR, Chatterjee AK, Neitz RJ, Arkin MR, McNamara CW, Ballard J, Lai Y, Fu Y, Molteni V, Yeh V, McKerrow JH, et al. Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease. Plos Pathogens. 11: e1005058. PMID 26186534 DOI: 10.1371/journal.ppat.1005058  0.88
2015 Neitz RJ, Bryant C, Chen S, Gut J, Hugo Caselli E, Ponce S, Chowdhury S, Xu H, Arkin MR, Ellman JA, Renslo AR. Tetrafluorophenoxymethyl ketone cruzain inhibitors with improved pharmacokinetic properties as therapeutic leads for Chagas' disease. Bioorganic & Medicinal Chemistry Letters. 25: 4834-7. PMID 26144347 DOI: 10.1016/j.bmcl.2015.06.066  0.88
2015 Chimenti MS, Bulfer SL, Neitz RJ, Renslo AR, Jacobson MP, James TL, Arkin MR, Kelly MJ. A Fragment-Based Ligand Screen Against Part of a Large Protein Machine: The ND1 Domains of the AAA+ ATPase p97/VCP. Journal of Biomolecular Screening. 20: 788-800. PMID 25690569 DOI: 10.1177/1087057115570550  0.88
2015 Alverez C, Arkin MR, Bulfer SL, Colombo R, Kovaliov M, Laporte MG, Lim C, Liang M, Moore WJ, Neitz RJ, Yan Y, Yue Z, Huryn DM, Wipf P. Structure-Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97 Acs Medicinal Chemistry Letters. 6: 1225-1230. DOI: 10.1021/acsmedchemlett.5b00364  0.88
2013 Ng RA, Sun M, Bowers S, Hom RK, Probst GD, John V, Fang LY, Maillard M, Gailunas A, Brogley L, Neitz RJ, Tung JS, Pleiss MA, Konradi AW, Sham HL, et al. Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: prime side chromane-containing inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 4674-9. PMID 23856050 DOI: 10.1016/j.bmcl.2013.06.006  0.88
2013 Aubele DL, Hom RK, Adler M, Galemmo RA, Bowers S, Truong AP, Pan H, Beroza P, Neitz RJ, Yao N, Lin M, Tonn G, Zhang H, Bova MP, Ren Z, et al. Selective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce α-synuclein phosphorylation in rat brain. Chemmedchem. 8: 1295-313. PMID 23794260 DOI: 10.1002/cmdc.201300166  0.88
2013 Bowers S, Truong AP, Ye M, Aubele DL, Sealy JM, Neitz RJ, Hom RK, Chan W, Dappen MS, Galemmo RA, Konradi AW, Sham HL, Zhu YL, Beroza P, Tonn G, et al. Design and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 2743-9. PMID 23522834 DOI: 10.1016/j.bmcl.2013.02.065  0.88
2013 Garofalo AW, Adler M, Aubele DL, Bowers S, Franzini M, Goldbach E, Lorentzen C, Neitz RJ, Probst GD, Quinn KP, Santiago P, Sham HL, Tam D, Truong AP, Ye XM, et al. Novel cinnoline-based inhibitors of LRRK2 kinase activity. Bioorganic & Medicinal Chemistry Letters. 23: 71-4. PMID 23219325 DOI: 10.1016/j.bmcl.2012.11.021  0.88
2011 Neitz RJ, Konradi AW, Sham HL, Zmolek W, Wong K, Qin A, Lorentzen C, Nakamura D, Quinn KP, Sauer JM, Powell K, Ruslim L, Chereau D, Ren Z, Anderson J, et al. Highly selective c-Jun N-terminal kinase (JNK) 3 inhibitors with in vitro CNS-like pharmacokinetic properties II. Central core replacement. Bioorganic & Medicinal Chemistry Letters. 21: 3726-9. PMID 21570836 DOI: 10.1016/j.bmcl.2011.04.074  0.88
2011 Bowers S, Truong AP, Neitz RJ, Neitzel M, Probst GD, Hom RK, Peterson B, Galemmo RA, Konradi AW, Sham HL, Tóth G, Pan H, Yao N, Artis DR, Brigham EF, et al. Design and synthesis of a novel, orally active, brain penetrant, tri-substituted thiophene based JNK inhibitor. Bioorganic & Medicinal Chemistry Letters. 21: 1838-43. PMID 21316234 DOI: 10.1016/j.bmcl.2011.01.046  0.88
2010 Hom RK, Bowers S, Sealy JM, Truong AP, Probst GD, Neitzel ML, Neitz RJ, Fang L, Brogley L, Wu J, Konradi AW, Sham HL, Tóth G, Pan H, Yao N, et al. Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK. Bioorganic & Medicinal Chemistry Letters. 20: 7303-7. PMID 21071223 DOI: 10.1016/j.bmcl.2010.10.066  0.88
2004 Roush WR, Neitz RJ. Studies on the synthesis of landomycin A. Synthesis of the originally assigned structure of the aglycone, landomycinone, and revision of structure. The Journal of Organic Chemistry. 69: 4906-12. PMID 15255715 DOI: 10.1021/jo049426c  0.88
2003 Shenai BR, Lee BJ, Alvarez-Hernandez A, Chong PY, Emal CD, Neitz RJ, Roush WR, Rosenthal PJ. Structure-activity relationships for inhibition of cysteine protease activity and development of Plasmodium falciparum by peptidyl vinyl sulfones. Antimicrobial Agents and Chemotherapy. 47: 154-60. PMID 12499184 DOI: 10.1128/AAC.47.1.154-160.2003  0.88
1993 Creaser I, Heckel MC, Neitz RJ, Pope MT. Rigid nonlabile polyoxometalate cryptaptes [ZP5W30O110](15-n)- that exhibit unprecedented selectivity for certain lanthanide and other multivalent cations Inorganic Chemistry. 32: 1573-1578.  0.88
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