Amanda L. Garner, Ph.D. - Publications

2003-2008 Chemistry University of Pittsburgh, Pittsburgh, PA, United States 
 2014- Chemistry University of Michigan, Ann Arbor, Ann Arbor, MI 
Chemical Biology

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Song JM, Gallagher EE, Menon A, Mishra LD, Garner AL. The role of olefin geometry in the activity of hydrocarbon stapled peptides targeting eukaryotic translation initiation factor 4E (eIF4E). Organic & Biomolecular Chemistry. PMID 31215581 DOI: 10.1039/c9ob01041f  0.32
2019 Garner AL, Lorenz DA, Sandoval J, Gallagher EE, Kerk SA, Kaur T, Menon A. Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition. Acs Medicinal Chemistry Letters. 10: 816-821. PMID 31098005 DOI: 10.1021/acsmedchemlett.9b00091  0.32
2019 Mitchell DC, Menon A, Garner AL. Chemoproteomic Profiling Uncovers CDK4-Mediated Phosphorylation of the Translational Suppressor 4E-BP1. Cell Chemical Biology. PMID 31056462 DOI: 10.1016/j.chembiol.2019.03.012  0.32
2019 Gallagher E, Song JM, Menon A, Mishra L, Chmiel AF, Garner AL. Consideration of Binding Kinetics in the Design of Stapled Peptide Mimics of the Disordered Proteins Eukaryotic Translation Initiation Factor 4E (eIF4E)-Binding Protein 1 (4E-BP1) and Eukaryotic Translation Initiation Factor 4G (eIF4G). Journal of Medicinal Chemistry. PMID 31033289 DOI: 10.1021/acs.jmedchem.9b00068  0.32
2019 Kaur T, Menon A, Garner AL. Synthesis of 7-benzylguanosine cap-analogue conjugates for eIF4E targeted degradation. European Journal of Medicinal Chemistry. 166: 339-350. PMID 30735900 DOI: 10.1016/j.ejmech.2019.01.080  0.32
2017 Song JM, Menon A, Mitchell DC, Johnson OT, Garner AL. High-Throughput Chemical Probing of Full-Length Protein-Protein Interactions. Acs Combinatorial Science. PMID 29112379 DOI: 10.1021/acscombsci.7b00128  0.32
2016 Hart JR, Weinberg MS, Morris KV, Roberts TC, Janda KD, Garner AL, Vogt PK. MINCR is not a MYC-induced lncRNA. Proceedings of the National Academy of Sciences of the United States of America. PMID 26811502 DOI: 10.1073/pnas.1519903113  1
2015 Lorenz DA, Song JM, Garner AL. High-throughput platform assay technology for the discovery of pre-microrna-selective small molecule probes. Bioconjugate Chemistry. 26: 19-23. PMID 25506628 DOI: 10.1021/bc500544v  1
2014 Hart JR, Garner AL, Yu J, Ito Y, Sun M, Ueno L, Rhee JK, Baksh MM, Stefan E, Hartl M, Bister K, Vogt PK, Janda KD. Inhibitor of MYC identified in a Kröhnke pyridine library. Proceedings of the National Academy of Sciences of the United States of America. 111: 12556-61. PMID 25114221 DOI: 10.1073/pnas.1319488111  1
2013 Garner AL, Kim SK, Zhu J, Struss AK, Watkins R, Feske BD, Kaufmann GF, Janda KD. Retraction: Stereochemical insignificance discovered in Acinetobacter baumannii quorum sensing (PLoS ONE) Plos One. 8. PMID 23853689 DOI: 10.1371/annotation/1345f9b0-016e-4123-9e72-6ccc4fa17ba2  1
2013 Garner AL, Fullagar JL, Day JA, Cohen SM, Janda KD. Development of a high-throughput screen and its use in the discovery of Streptococcus pneumoniae immunoglobulin A1 protease inhibitors. Journal of the American Chemical Society. 135: 10014-7. PMID 23808771 DOI: 10.1021/ja404180x  1
2013 Kravchenko V, Garner AL, Mathison J, Seit-Nebi A, Yu J, Gileva IP, Ulevitch R, Janda KD. Facilitating cytokine-mediated cancer cell death by proteobacterial N-acylhomoserine lactones. Acs Chemical Biology. 8: 1117-20. PMID 23517377 DOI: 10.1021/cb4000184  1
2013 Fullagar JL, Garner AL, Struss AK, Day JA, Martin DP, Yu J, Cai X, Janda KD, Cohen SM. Antagonism of a zinc metalloprotease using a unique metal-chelating scaffold: tropolones as inhibitors of P. aeruginosa elastase. Chemical Communications (Cambridge, England). 49: 3197-9. PMID 23482955 DOI: 10.1039/c3cc41191e  1
2013 Garner AL, Yu J, Struss AK, Kaufmann GF, Kravchenko VV, Janda KD. Immunomodulation and the quorum sensing molecule 3-oxo-C12-homoserine lactone: the importance of chemical scaffolding for probe development. Chemical Communications (Cambridge, England). 49: 1515-7. PMID 23328974 DOI: 10.1039/c3cc38851d  1
2012 Garner AL, Struss AK, Fullagar JL, Agrawal A, Moreno AY, Cohen SM, Janda KD. 3-Hydroxy-1-alkyl-2-methylpyridine-4(1H)-thiones: Inhibition of the Pseudomonas aeruginosa Virulence Factor LasB. Acs Medicinal Chemistry Letters. 3: 668-672. PMID 23181168 DOI: 10.1021/ml300128f  1
2012 Garner AL, Kim SK, Zhu J, Struss AK, Watkins R, Feske BD, Kaufmann GF, Janda KD. Stereochemical insignificance discovered in Acinetobacter baumannii quorum sensing. Plos One. 7: e37102. PMID 22629354 DOI: 10.1371/journal.pone.0037102  1
2011 Li Z, Garner AL, Gloeckner C, Janda KD, Carlow CK. Targeting the Wolbachia cell division protein FtsZ as a new approach for antifilarial therapy. Plos Neglected Tropical Diseases. 5: e1411. PMID 22140592 DOI: 10.1371/journal.pntd.0001411  1
2011 Garner AL, Park J, Zakhari JS, Lowery CA, Struss AK, Sawada D, Kaufmann GF, Janda KD. A multivalent probe for AI-2 quorum-sensing receptors. Journal of the American Chemical Society. 133: 15934-7. PMID 21913711 DOI: 10.1021/ja207556d  1
2011 Koide K, Osman S, Garner AL, Song F, Dixon T, Greenberger JS, Epperly MW. The Use of 3,5,4'-Tri-O-acetylresveratrol as a Potential Pro-drug for Resveratrol Protects Mice from γ-Irradiation-Induced Death. Acs Medicinal Chemistry Letters. 2: 270-274. PMID 21826253 DOI: 10.1021/ml100159p  1
2011 Garner AL, Janda KD. A small molecule antagonist of ghrelin O-acyltransferase (GOAT). Chemical Communications (Cambridge, England). 47: 7512-4. PMID 21594284 DOI: 10.1039/c1cc11817j  1
2011 Garner AL, Gloeckner C, Tricoche N, Zakhari JS, Samje M, Cho-Ngwa F, Lustigman S, Janda KD. Design, synthesis, and biological activities of closantel analogues: structural promiscuity and its impact on Onchocerca volvulus. Journal of Medicinal Chemistry. 54: 3963-72. PMID 21534605 DOI: 10.1021/jm200364n  1
2011 Uckun FM, Qazi S, Ozer Z, Garner AL, Pitt J, Ma H, Janda KD. Inducing apoptosis in chemotherapy-resistant B-lineage acute lymphoblastic leukaemia cells by targeting HSPA5, a master regulator of the anti-apoptotic unfolded protein response signalling network. British Journal of Haematology. 153: 741-52. PMID 21517817 DOI: 10.1111/j.1365-2141.2011.08671.x  1
2011 Kirchdoerfer RN, Garner AL, Flack CE, Mee JM, Horswill AR, Janda KD, Kaufmann GF, Wilson IA. Structural basis for ligand recognition and discrimination of a quorum-quenching antibody. The Journal of Biological Chemistry. 286: 17351-8. PMID 21454495 DOI: 10.1074/jbc.M111.231258  1
2011 Garner AL, Janda KD. Protein-protein interactions and cancer: targeting the central dogma. Current Topics in Medicinal Chemistry. 11: 258-80. PMID 21320057 DOI: 10.2174/156802611794072614  1
2011 Garner AL, Janda KD. Shedding light on the ghrelin/GOAT metabolism saga. Chembiochem : a European Journal of Chemical Biology. 12: 523-5. PMID 21254317 DOI: 10.1002/cbic.201000777  1
2011 Garner AL, Yu J, Struss AK, Lowery CA, Zhu J, Kim SK, Park J, Mayorov AV, Kaufmann GF, Kravchenko VV, Janda KD. Synthesis of 'clickable' acylhomoserine lactone quorum sensing probes: unanticipated effects on mammalian cell activation. Bioorganic & Medicinal Chemistry Letters. 21: 2702-5. PMID 21190852 DOI: 10.1016/j.bmcl.2010.11.122  1
2010 Garner AL, Janda KD. cat-ELCCA: a robust method to monitor the fatty acid acyltransferase activity of ghrelin O-acyltransferase (GOAT). Angewandte Chemie (International Ed. in English). 49: 9630-4. PMID 20845345 DOI: 10.1002/anie.201003387  1
2010 Gloeckner C, Garner AL, Mersha F, Oksov Y, Tricoche N, Eubanks LM, Lustigman S, Kaufmann GF, Janda KD. Repositioning of an existing drug for the neglected tropical disease Onchocerciasis. Proceedings of the National Academy of Sciences of the United States of America. 107: 3424-9. PMID 20142509 DOI: 10.1073/pnas.0915125107  1
2009 Garner AL, St Croix CM, Pitt BR, Leikauf GD, Ando S, Koide K. Specific fluorogenic probes for ozone in biological and atmospheric samples. Nature Chemistry. 1: 316-21. PMID 20634904 DOI: 10.1038/nchem.240  1
2009 Uchida T, Mills KL, Kuo CH, Roh W, Tung YC, Garner AL, Koide K, Thouless MD, Takayama S. External compression-induced fracture patterning on the surface of poly(dimethylsiloxane) cubes and microspheres. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 3102-7. PMID 19437776 DOI: 10.1021/la801986k  1
2009 Garner AL, Song F, Koide K. Enhancement of a catalysis-based fluorometric detection method for palladium through rational fine-tuning of the palladium species. Journal of the American Chemical Society. 131: 5163-71. PMID 19317401 DOI: 10.1021/ja808385a  1
2009 Garner AL, Koide K. Studies of a fluorogenic probe for palladium and platinum leading to a palladium-specific detection method. Chemical Communications (Cambridge, England). 86-8. PMID 19082007 DOI: 10.1039/b814197e  1
2009 Garner AL, Koide K. Fluorescent method for platinum detection in buffers and serums for cancer medicine and occupational hazards. Chemical Communications (Cambridge, England). 83-5. PMID 19082006 DOI: 10.1039/b817220j  1
2008 Garner AL, Koide K. Oxidation state-specific fluorescent method for palladium(II) and platinum(IV) based on the catalyzed aromatic claisen rearrangement. Journal of the American Chemical Society. 130: 16472-3. PMID 19554719 DOI: 10.1021/ja8065539  1
2008 Koide K, Song F, de Groh ED, Garner AL, Mitchell VD, Davidson LA, Hukriede NA. Scalable and concise synthesis of dichlorofluorescein derivatives displaying tissue permeation in live zebrafish embryos. Chembiochem : a European Journal of Chemical Biology. 9: 214-8. PMID 18161734 DOI: 10.1002/cbic.200700565  1
2007 Garner AL, Koide K. Solid-phase olefin cross-metathesis promoted by a linker. Organic Letters. 9: 5235-8. PMID 18001044 DOI: 10.1021/ol702415x  1
2007 Song F, Garner AL, Koide K. A highly sensitive fluorescent sensor for palladium based on the allylic oxidative insertion mechanism. Journal of the American Chemical Society. 129: 12354-5. PMID 17887672 DOI: 10.1021/ja073910q  1
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