Hien M. Nguyen, Ph.D. - Publications

Affiliations: 
2006-2009 Chemistry Montana State University, Bozeman, MT 
 2009- Chemistry University of Iowa, Iowa City, IA 
 2018- Chemistry Wayne State University, Detroit, MI, United States 
Area:
Complex carbohydrates
Website:
https://s.wayne.edu/nguyengroup/hien-nguyen/

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Usman FO, Gogoi AR, Mixdorf JC, Gutierrez O, Nguyen HM. Rhodium-Catalyzed Asymmetric Synthesis of 1,2-Disubstituted Allylic Fluorides. Angewandte Chemie (International Ed. in English). 62: e202314843. PMID 37856668 DOI: 10.1002/anie.202314843  0.352
2023 Abdulsalam H, Li J, Loka RS, Sletten ET, Nguyen HM. Heparan Sulfate-Mimicking Glycopolymers Bind SARS-CoV-2 Spike Protein in a Length- and Sulfation Pattern-Dependent Manner. Acs Medicinal Chemistry Letters. 14: 1411-1418. PMID 37849547 DOI: 10.1021/acsmedchemlett.3c00319  0.663
2023 Arachchi MK, Schaugaard RN, Schlegel HB, Nguyen HM. Scope and Mechanistic Probe into Asymmetric Synthesis of α-Trisubstituted-α-Tertiary Amines by Rhodium Catalysis. Journal of the American Chemical Society. PMID 37651695 DOI: 10.1021/jacs.3c04211  0.354
2022 Li J, Nguyen HM. Phenanthroline Catalysis in Stereoselective 1,2- Glycosylations. Accounts of Chemical Research. PMID 36448710 DOI: 10.1021/acs.accounts.2c00636  0.358
2022 Loka RS, Song Z, Sletten ET, Kayal Y, Vlodavsky I, Zhang K, Nguyen HM. Heparan Sulfate Mimicking Glycopolymer Prevents Pancreatic β Cell Destruction and Suppresses Inflammatory Cytokine Expression in Islets under the Challenge of Upregulated Heparanase. Acs Chemical Biology. PMID 35658404 DOI: 10.1021/acschembio.1c00908  0.67
2022 Xu H, Schaugaard RN, Li J, Schlegel HB, Nguyen HM. Stereoselective 1,2- Furanosylations Catalyzed by Phenanthroline. Journal of the American Chemical Society. 144: 7441-7456. PMID 35413194 DOI: 10.1021/jacs.2c02063  0.31
2021 Li J, Nguyen HM. A Mechanistic Probe into 1,2- Glycoside Formation Catalyzed by Phenanthroline and Further Expansion of Scope. Advanced Synthesis & Catalysis. 363: 4054-4066. PMID 35431716 DOI: 10.1002/adsc.202100639  0.317
2021 DeMent PM, Liu C, Wakpal J, Schaugaard RN, Schlegel HB, Nguyen HM. Phenanthroline-Catalyzed Stereoselective Formation of -1,2- 2-Deoxy-2-Fluoro Glycosides. Acs Catalysis. 11: 2108-2120. PMID 34336371 DOI: 10.1021/acscatal.0c04381  0.311
2020 Rodrigo S, Um C, Mixdorf JC, Gunasekera D, Nguyen HM, Luo L. Alternating Current Electrolysis for Organic Electrosynthesis: Trifluoromethylation of (Hetero)arenes. Organic Letters. PMID 32658484 DOI: 10.1021/Acs.Orglett.0C01906  0.334
2020 Zhu S, Li J, Loka R, Song Z, Vlodavsky I, Zhang K, Nguyen HM. Modulating Heparanase Activity: Tuning Sulfation Pattern and Glycosidic Linkage of Oligosaccharides. Journal of Medicinal Chemistry. PMID 32216347 DOI: 10.1021/Acs.Jmedchem.0C00156  0.383
2020 Yu F, Dickson JL, Loka RS, Xu H, Schaugaard RN, Schlegel HB, Luo L, Nguyen HM. Diastereoselective sp3 C–O Bond Formation via Visible Light-Induced, Copper-Catalyzed Cross-Couplings of Glycosyl Bromides with Aliphatic Alcohols Acs Catalysis. 10: 5990-6001. DOI: 10.1021/Acscatal.0C01470  0.314
2019 Zhu S, Samala G, Sletten ET, Stockdill JL, Nguyen HM. Facile triflic acid-catalyzed α-1,2--thio glycosylations: scope and application to the synthesis of -linked oligosaccharides, glycolipids, sublancin glycopeptides, and T/T antigens. Chemical Science. 10: 10475-10480. PMID 32110337 DOI: 10.1039/C9Sc04079J  0.752
2019 Sletten ET, Tu YJ, Schlegel HB, Nguyen HM. Are Brønsted Acids the True Promoter of Metal-Triflate-Catalyzed Glycosylations? A Mechanistic Probe into 1,2--Aminoglycoside Formation by Nickel Triflate. Acs Catalysis. 9: 2110-2123. PMID 31819822 DOI: 10.1021/Acscatal.8B04444  0.737
2019 Sorlin AM, Mixdorf JC, Rotella M, Martin R, Gutierrez O, Nguyen HM. The Role of Trichloroacetimidate To Enable Iridium-Catalyzed Regio- and Enantioselective Allylic Fluorination: A Combined Experimental and Computational Study. Journal of the American Chemical Society. PMID 31438667 DOI: 10.1021/Jacs.9B07575  0.456
2019 Nguyen HM, Yu F, Li J, DeMent PM, Tu YJ, Schlegel HB. Phenanthroline-Catalyzed Stereoretentive Glycosylations. Angewandte Chemie (International Ed. in English). PMID 30920099 DOI: 10.1002/Anie.201901346  0.399
2018 Mixdorf JC, Sorlin AM, Dick DW, Nguyen HM. Iridium-Catalyzed Radiosynthesis of Branched Allylic [F]Fluorides. Organic Letters. PMID 30575403 DOI: 10.1021/Acs.Orglett.8B03496  0.347
2018 Loka RS, Sletten ET, Barash U, Vlodavsky I, Nguyen HM. Specific Inhibition of Heparanase by Glycopolymer with Well-Defined Sulfation Pattern Prevents Breast Cancer Metastasis in Mice. Acs Applied Materials & Interfaces. PMID 30543095 DOI: 10.1021/Acsami.8B17625  0.689
2017 Mwenda ET, Nguyen HM. Enantioselective Synthesis of 1,2-Diamines Containing Tertiary and Quaternary Centers through Rhodium-Catalyzed DYKAT of Racemic Allylic Trichloroacetimidates. Organic Letters. PMID 28876951 DOI: 10.1021/Acs.Orglett.7B02256  0.461
2017 Sletten ET, Loka RS, Yu F, Nguyen HM. Glycosidase Inhibition by Multivalent Presentation of Heparan Sulfate Saccharides on Bottlebrush Polymers. Biomacromolecules. PMID 28846389 DOI: 10.1021/Acs.Biomac.7B01049  0.686
2017 Loka RS, Yu F, Sletten ET, Nguyen HM. Design, synthesis, and evaluation of heparan sulfate mimicking glycopolymers for inhibiting heparanase activity. Chemical Communications (Cambridge, England). PMID 28766595 DOI: 10.1039/C7Cc04156J  0.688
2017 Mixdorf JC, Sorlin AM, Zhang Q, Nguyen HM. Asymmetric Synthesis of Allylic Fluorides via Fluorination of Racemic Allylic Trichloroacetimidates Catalyzed by a Chiral Diene-Iridium Complex Acs Catalysis. 8: 790-801. DOI: 10.1021/Acscatal.7B03786  0.448
2016 Sletten ET, Ramadugu SK, Nguyen HM. Utilization of bench-stable and readily available nickel(II) triflate for access to 1,2-cis-2-aminoglycosides. Carbohydrate Research. 435: 195-207. PMID 27816838 DOI: 10.1016/J.Carres.2016.10.008  0.746
2015 Loka RS, McConnell MS, Nguyen HM. Studies of Highly-Ordered Heterodiantennary Mannose/Glucose-Functionalized Polymers and Concanavalin A Protein Interactions Using Isothermal Titration Calorimetry. Biomacromolecules. PMID 26580410 DOI: 10.1021/Acs.Biomac.5B01380  0.552
2015 Zhang Q, Stockdale DP, Mixdorf JC, Topczewski JJ, Nguyen HM. Iridium-Catalyzed Enantioselective Fluorination of Racemic, Secondary Allylic Trichloroacetimidates. Journal of the American Chemical Society. 137: 11912-5. PMID 26348569 DOI: 10.1021/Jacs.5B07492  0.681
2015 Sletten ET, Svec RL, Nguyen HM. Synthesis of a polymerizable, bivalent glycan mimetic of the HIV envelope spike gp120. Tetrahedron Letters. 56: 3473-3476. PMID 26019370 DOI: 10.1016/J.Tetlet.2015.01.016  0.702
2015 Yu F, McConnell MS, Nguyen HM. Scalable synthesis of Fmoc-protected GalNAc-threonine amino acid and T(N) antigen via nickel catalysis. Organic Letters. 17: 2018-21. PMID 25853273 DOI: 10.1021/Acs.Orglett.5B00780  0.605
2015 Zhang Q, Mixdorf JC, Reynders GJ, Nguyen HM. Rhodium-catalyzed benzylic fluorination of trichloroacetimidates Tetrahedron. 71: 5932-5938. DOI: 10.1016/J.Tet.2015.04.066  0.438
2014 McKay MJ, Park NH, Nguyen HM. Investigations of scope and mechanism of nickel-catalyzed transformations of glycosyl trichloroacetimidates to glycosyl trichloroacetamides and subsequent, atom-economical, one-step conversion to α-urea-glycosides. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 8691-701. PMID 24905328 DOI: 10.1002/Chem.201402433  0.625
2014 Arnold JS, Mwenda ET, Nguyen HM. Rhodium-catalyzed sequential allylic amination and olefin hydroacylation reactions: enantioselective synthesis of seven-membered nitrogen heterocycles. Angewandte Chemie (International Ed. in English). 53: 3688-92. PMID 24591294 DOI: 10.1002/Anie.201310354  0.688
2014 McKay MJ, Nguyen HM. Recent developments in glycosyl urea synthesis. Carbohydrate Research. 385: 18-44. PMID 24398301 DOI: 10.1016/J.Carres.2013.08.007  0.577
2014 Zhang Q, Nguyen HM. Rhodium-catalyzed regioselective opening of vinyl epoxides with Et 3N·3HF reagent-formation of allylic fluorohydrins Chemical Science. 5: 291-296. DOI: 10.1039/C3Sc51949J  0.431
2014 Arnold JS, Zhang Q, Nguyen HM. Transition-metal-catalyzed allylic substitutions of trichloroacetimidates European Journal of Organic Chemistry. 2014: 4925-4948. DOI: 10.1002/Ejoc.201402097  0.672
2013 McConnell MS, Mensah EA, Nguyen HM. Stereoselective α-glycosylation of C(6)-hydroxyl myo-inositols via nickel catalysis-application to the synthesis of GPI anchor pseudo-oligosaccharides. Carbohydrate Research. 381: 146-52. PMID 24121123 DOI: 10.1016/J.Carres.2013.09.006  0.756
2013 McConnell MS, Yu F, Nguyen HM. Nickel-catalyzed α-glycosylation of C(1)-hydroxyl D-myo-inositol: a formal synthesis of mycothiol. Chemical Communications (Cambridge, England). 49: 4313-5. PMID 22992771 DOI: 10.1039/C2Cc35823A  0.623
2013 Arnold JS, Nguyen HM. Rhodium-catalyzed asymmetric amination of allylic trichloroacetimidates Synthesis (Germany). 45: 2101-2108. DOI: 10.1055/S-0032-1316921  0.684
2012 Arnold JS, Cizio GT, Heitz DR, Nguyen HM. Rhodium-catalyzed regio- and enantioselective amination of racemic secondary allylic trichloroacetimidates with N-methyl anilines. Chemical Communications (Cambridge, England). 48: 11531-3. PMID 23090208 DOI: 10.1039/C2Cc36961C  0.656
2012 McKay MJ, Nguyen HM. Recent Advances in Transition Metal-Catalyzed Glycosylation. Acs Catalysis. 2: 1563-1595. PMID 22924154 DOI: 10.1021/Cs3002513  0.566
2012 Yu F, Nguyen HM. Studies on the selectivity between nickel-catalyzed 1,2-cis-2-amino glycosylation of hydroxyl groups of thioglycoside acceptors with C2-substituted benzylidene N-phenyl trifluoroacetimidates and intermolecular aglycon transfer of the sulfide group. The Journal of Organic Chemistry. 77: 7330-43. PMID 22838405 DOI: 10.1021/Jo301050Q  0.454
2012 Arnold JS, Nguyen HM. Rhodium-catalyzed dynamic kinetic asymmetric transformations of racemic tertiary allylic trichloroacetimidates with anilines. Journal of the American Chemical Society. 134: 8380-3. PMID 22563701 DOI: 10.1021/Ja302223P  0.678
2011 Topczewski JJ, Tewson TJ, Nguyen HM. Iridium-catalyzed allylic fluorination of trichloroacetimidates. Journal of the American Chemical Society. 133: 19318-21. PMID 22059470 DOI: 10.1021/Ja2087213  0.652
2011 Arnold JS, Cizio GT, Nguyen HM. Synthesis of α,α-disubstituted aryl amines by rhodium-catalyzed amination of tertiary allylic trichloroacetimidates. Organic Letters. 13: 5576-9. PMID 21958228 DOI: 10.1021/Ol202313Y  0.691
2011 Trost BM, Nguyen HM, Koradin C. Reprint of: Synthesis of a tricyclic core of rameswaralide Tetrahedron Letters. 52: 2033-2036. DOI: 10.1016/J.Tetlet.2011.03.001  0.452
2010 Trost BM, Nguyen HM, Koradin C. Synthesis of a Tricyclic Core of Rameswaralide. Tetrahedron Letters. 41: 6232-6235. PMID 21076637 DOI: 10.1016/J.Tetlet.2010.09.042  0.452
2010 Mensah EA, Yu F, Nguyen HM. Nickel-catalyzed stereoselective glycosylation with C(2)-N-substituted benzylidene D-glucosamine and galactosamine trichloroacetimidates for the formation of 1,2-cis-2-amino glycosides. Applications to the synthesis of heparin disaccharides, GPI anchor pseudodisaccharides, and α-GalNAc. Journal of the American Chemical Society. 132: 14288-302. PMID 20860359 DOI: 10.1021/Ja106682M  0.695
2010 Arnold JS, Stone RF, Nguyen HM. Rhodium-catalyzed regioselective amination of secondary allylic trichloroacetimidates with unactivated aromatic amines. Organic Letters. 12: 4580-3. PMID 20843019 DOI: 10.1021/Ol1019025  0.687
2009 Mensah EA, Nguyen HM. Nickel-catalyzed stereoselective formation of alpha-2-deoxy-2-amino glycosides. Journal of the American Chemical Society. 131: 8778-80. PMID 19496537 DOI: 10.1021/Ja903123B  0.659
2009 McKay MJ, Naab BD, Mercer GJ, Nguyen HM. Selective formation of beta-O-aryl glycosides in the absence of the C(2)-ester neighboring group. The Journal of Organic Chemistry. 74: 4705-11. PMID 19485363 DOI: 10.1021/Jo9002807  0.724
2009 Park NH, Nguyen HM. Stereoselective rearrangement of trichloroacetimidates: application to the synthesis of alpha-glycosyl ureas. Organic Letters. 11: 2433-6. PMID 19473048 DOI: 10.1021/Ol900670A  0.34
2009 Mensah EA, Azzarelli JM, Nguyen HM. Palladium-controlled beta-selective glycosylation in the absence of the C(2)-ester participatory group. The Journal of Organic Chemistry. 74: 1650-7. PMID 19161277 DOI: 10.1021/Jo802468P  0.77
2009 Mensah EA, Azzarelli JM, Nguyen HM. ChemInform Abstract: Palladium-Controlled β-Selective Glycosylation in the Absence of the C(2)-Ester Participatory Group. Cheminform. 40. DOI: 10.1002/chin.200927181  0.762
2008 Mercer GJ, Yang J, McKay MJ, Nguyen HM. Palladium(II)-catalyzed rearrangement of glycal trichloroacetimidates: application to the stereoselective synthesis of glycosyl ureas. Journal of the American Chemical Society. 130: 11210-8. PMID 18642810 DOI: 10.1021/Ja803378K  0.71
2008 Yang J, Cooper-Vanosdell C, Mensah EA, Nguyen HM. Cationic palladium(II)-catalyzed stereoselective glycosylation with glycosyl trichloroacetimidates. The Journal of Organic Chemistry. 73: 794-800. PMID 18184010 DOI: 10.1021/Jo702436P  0.642
2008 Yang J, Mercer GJ, Nguyen HM. ChemInform Abstract: Palladium-Catalyzed Glycal Imidate Rearrangement: Formation of α- and β-N-Glycosyl Trichloroacetamides. Cheminform. 39. DOI: 10.1002/chin.200813186  0.57
2007 Yang J, Mercer GJ, Nguyen HM. Palladium-catalyzed glycal imidate rearrangement: formation of alpha- and beta-N-glycosyl trichloroacetamides. Organic Letters. 9: 4231-4. PMID 17880097 DOI: 10.1021/Ol701778Z  0.607
2007 Schuff BP, Mercer GJ, Nguyen HM. Palladium-catalyzed stereoselective formation of alpha-O-glycosides. Organic Letters. 9: 3173-6. PMID 17616145 DOI: 10.1021/Ol071268Z  0.782
2007 Schuff BP, Mercer GJ, Nguyen HM. Palladium-Catalyzed Stereoselective Formation of α-O-Glycosides. Cheminform. 38. DOI: 10.1002/chin.200749193  0.769
2001 Nguyen HM, Poole JL, Gin DY. Chemoselective Iterative Dehydrative Glycosylation. Angewandte Chemie (International Ed. in English). 40: 414-417. PMID 29712399 DOI: 10.1002/1521-3773(20010119)40:2<414::AID-ANIE414>3.0.CO;2-6  0.61
2001 Nguyen HM, Chen Y, Duron SG, Gin DY. Sulfide-mediated dehydrative glycosylation. Journal of the American Chemical Society. 123: 8766-72. PMID 11535081 DOI: 10.1021/Ja015968P  0.766
2001 Nguyen HM, Poole JL, Gin DY. Chemoselective Iterative Dehydrative Glycosylation This research was supported by the National Institutes of Health (Grant no.: GM-58833), the Arnold and Mabel Beckman Foundation (BYI), Glaxo Wellcome Inc., and the Alfred P. Sloan Foundation. D.Y.G. is a Cottrell Scholar of Research Corporation. Angewandte Chemie (International Ed. in English). 40: 414-417. PMID 11180342 DOI: 10.1002/1521-3773(20010119)40:2<414::AID-ANIE414>3.0.CO;2-6  0.527
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