Christopher W. Cunningham, Ph.D. - Publications

Affiliations: 
2003-2008 Pharmaceutical Sciences University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Medicinal Chemistry
Website:
https://cunninghamlab.wordpress.com/

23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Rehrauer KJ, Cunningham CW. IUPHAR Review - Bivalent and bifunctional opioid receptor ligands as novel analgesics. Pharmacological Research. 197: 106966. PMID 37865129 DOI: 10.1016/j.phrs.2023.106966  0.529
2023 Olson KM, Devereaux AL, Chatterjee P, Saldaña-Shumaker SL, Shafer A, Plotkin A, Kandasamy R, MacKerell AD, Traynor JR, Cunningham CW. Nitro-benzylideneoxymorphone, a bifunctional mu and delta opioid receptor ligand with high mu opioid receptor efficacy. Frontiers in Pharmacology. 14: 1230053. PMID 37469877 DOI: 10.3389/fphar.2023.1230053  0.537
2021 Terashvili M, Talluri B, Palangmonthip W, Iczkowski KA, Sanvanson P, Medda BK, Banerjee B, Cunningham CW, Sengupta JN. Peripheral antinociceptive effects of a bifunctional μ and δ opioid receptor ligand in rat model of inflammatory bladder pain. Neuropharmacology. 196: 108701. PMID 34256047 DOI: 10.1016/j.neuropharm.2021.108701  0.41
2020 Mada S, Gerak LR, Soyer A, Maguire DR, Hu Z, Minervini V, Cunningham CW, France CP. Behavioral effects of benzylideneoxymorphone (BOM), a low efficacy µ opioid receptor agonist and a δ opioid receptor antagonist. Psychopharmacology. PMID 32820390 DOI: 10.1007/S00213-020-05638-1  0.526
2019 Cunningham CW, Elballa WM, Vold SU. Bifunctional opioid receptor ligands as novel analgesics. Neuropharmacology. PMID 30858102 DOI: 10.1016/j.neuropharm.2019.03.006  0.495
2018 Burns SM, Cunningham CW, Mercer SL. DARK Classics in Chemical Neuroscience: Fentanyl. Acs Chemical Neuroscience. PMID 29894151 DOI: 10.1021/acschemneuro.8b00174  0.75
2018 Devereaux AL, Mercer SL, Cunningham CW. DARK Classics in Chemical Neuroscience: Morphine. Acs Chemical Neuroscience. PMID 29757600 DOI: 10.1021/acschemneuro.8b00150  0.728
2016 Healy JR, Bezawada P, Griggs NW, Devereaux AL, Matsumoto RR, Traynor JR, Coop A, Cunningham CW. Benzylideneoxymorphone: A new lead for development of bifunctional mu/delta opioid receptor ligands. Bioorganic & Medicinal Chemistry Letters. PMID 28011222 DOI: 10.1016/j.bmcl.2016.11.057  0.706
2014 Cunningham CW, Deschamps JR, Coop A. A One-Step Synthesis of -Bromocodide from Codeine. Journal of Pharmaceutical Sciences and Pharmacology. 1: 54-56. PMID 34584903  0.603
2014 Metcalf MD, Rosicky AD, Hassan HE, Eddington ND, Coop A, Cunningham CW, Mercer SL. Opioids and efflux transporters. Part 4: influence of N-substitution on P-glycoprotein substrate activity of noroxymorphone analogues. Bioorganic & Medicinal Chemistry Letters. 24: 3592-5. PMID 24915880 DOI: 10.1016/J.Bmcl.2014.05.033  0.78
2014 Cunningham CW, Deschamps JR, Coop A. A One-Step Synthesis of -Bromocodide from Codeine Journal of Pharmaceutical Sciences and Pharmacology. 1: 54-56. DOI: 10.1166/jpsp.2014.1005  0.442
2013 Motel WC, Coop A, Cunningham CW. Cholinergic modulation by opioid receptor ligands: potential application to Alzheimer's disease. Mini Reviews in Medicinal Chemistry. 13: 456-66. PMID 22931533 DOI: 10.2174/138955713804999784  0.651
2011 Cunningham CW, Rothman RB, Prisinzano TE. Neuropharmacology of the naturally occurring kappa-opioid hallucinogen salvinorin A. Pharmacological Reviews. 63: 316-47. PMID 21444610 DOI: 10.1124/Pr.110.003244  0.682
2011 Lozama A, Cunningham CW, Caspers MJ, Douglas JT, Dersch CM, Rothman RB, Prisinzano TE. Opioid receptor probes derived from cycloaddition of the hallucinogen natural product salvinorin A. Journal of Natural Products. 74: 718-26. PMID 21338114 DOI: 10.1021/Np1007872  0.736
2010 Cunningham CW, Hom K, Acharya C, Wilks A, Mackerell AD, Coop A. Synthesis and Characterization of a Novel Diels - Alder Adduct of Codeine. Helvetica Chimica Acta. 93: 220-226. PMID 23378668 DOI: 10.1002/Hlca.200900234  0.544
2010 Cunningham CW, Mukhopadhyay A, Lushington GH, Blagg BS, Prisinzano TE, Krise JP. Uptake, distribution and diffusivity of reactive fluorophores in cells: implications toward target identification. Molecular Pharmaceutics. 7: 1301-10. PMID 20557111 DOI: 10.1021/Mp100089K  0.505
2009 Lovell KM, Simpson DS, Cunningham CW, Prisinzano TE. Utilizing nature as a source of new probes for opioid pharmacology. Future Medicinal Chemistry. 1: 285-301. PMID 21425970 DOI: 10.4155/Fmc.09.22  0.787
2009 Hassan HE, Mercer SL, Cunningham CW, Coop A, Eddington ND. Evaluation of the P-glycoprotein (Abcb1) affinity status of a series of morphine analogs: comparative study with meperidine analogs to identify opioids with minimal P-glycoprotein interactions. International Journal of Pharmaceutics. 375: 48-54. PMID 19481690 DOI: 10.1016/J.Ijpharm.2009.03.037  0.779
2008 Mercer SL, Cunningham CW, Eddington ND, Coop A. Opioids and efflux transporters. Part 3: P-glycoprotein substrate activity of 3-hydroxyl addition to meperidine analogs. Bioorganic & Medicinal Chemistry Letters. 18: 3638-40. PMID 18499452 DOI: 10.1016/J.Bmcl.2008.04.046  0.783
2008 Cunningham CW, Mercer SL, Hassan HE, Traynor JR, Eddington ND, Coop A. Opioids and efflux transporters. Part 2: P-glycoprotein substrate activity of 3- and 6-substituted morphine analogs. Journal of Medicinal Chemistry. 51: 2316-20. PMID 18311899 DOI: 10.1021/Jm701457J  0.798
2007 Mercer SL, Hassan HE, Cunningham CW, Eddington ND, Coop A. Opioids and efflux transporters. Part 1: P-glycoprotein substrate activity of N-substituted analogs of meperidine. Bioorganic & Medicinal Chemistry Letters. 17: 1160-2. PMID 17251015 DOI: 10.1016/J.Bmcl.2006.12.042  0.769
2006 Cunningham CW, Thatcher LN, Coop A. Methylation of non-acidic alcohols of alkaloids with TMS-diazomethane: Conversion of codeine to codeine-6-methyl ether Heterocycles. 68: 837-840. DOI: 10.3987/Com-06-10694  0.428
2006 Cunningham CW, Coop A. Therapeutic applications of opioid antagonists Chimica Oggi. 24: 54-57.  0.7
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