Howard Y. Chang - Publications

Affiliations: 
2014- Dermatology Stanford University, Palo Alto, CA 

256 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Durai V, Bagadia P, Granja JM, Satpathy AT, Kulkarni DH, Davidson JT, Wu R, Patel SJ, Iwata A, Liu TT, Huang X, Briseño CG, Grajales-Reyes GE, Wöhner M, Tagoh H, ... ... Chang HY, et al. Cryptic activation of an Irf8 enhancer governs cDC1 fate specification. Nature Immunology. PMID 31406378 DOI: 10.1038/s41590-019-0450-x  0.36
2019 Satpathy AT, Granja JM, Yost KE, Qi Y, Meschi F, McDermott GP, Olsen BN, Mumbach MR, Pierce SE, Corces MR, Shah P, Bell JC, Jhutty D, Nemec CM, Wang J, ... ... Chang HY, et al. Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion. Nature Biotechnology. 37: 925-936. PMID 31375813 DOI: 10.1038/s41587-019-0206-z  0.44
2019 Yost KE, Satpathy AT, Wells DK, Qi Y, Wang C, Kageyama R, McNamara KL, Granja JM, Sarin KY, Brown RA, Gupta RK, Curtis C, Bucktrout SL, Davis MM, Chang ALS, ... Chang HY, et al. Clonal replacement of tumor-specific T cells following PD-1 blockade. Nature Medicine. PMID 31359002 DOI: 10.1038/s41591-019-0522-3  0.44
2019 Lee J, Termglinchan V, Diecke S, Itzhaki I, Lam CK, Garg P, Lau E, Greenhaw M, Seeger T, Wu H, Zhang JZ, Chen X, Gil IP, Ameen M, Sallam K, ... ... Chang HY, et al. Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. Nature. PMID 31316208 DOI: 10.1038/s41586-019-1406-x  0.44
2019 Fazal FM, Han S, Parker KR, Kaewsapsak P, Xu J, Boettiger AN, Chang HY, Ting AY. Atlas of Subcellular RNA Localization Revealed by APEX-Seq. Cell. PMID 31230715 DOI: 10.1016/j.cell.2019.05.027  1
2019 Mumbach MR, Granja JM, Flynn RA, Roake CM, Satpathy AT, Rubin AJ, Qi Y, Jiang Z, Shams S, Louie BH, Guo JK, Gennert DG, Corces MR, Khavari PA, Atianand MK, ... ... Chang HY, et al. HiChIRP reveals RNA-associated chromosome conformation. Nature Methods. PMID 31133759 DOI: 10.1038/s41592-019-0407-x  0.44
2019 Xu J, Nuno K, Litzenburger UM, Qi Y, Corces MR, Majeti R, Chang HY. Single-cell lineage tracing by endogenous mutations enriched in transposase accessible mitochondrial DNA. Elife. 8. PMID 30958261 DOI: 10.7554/eLife.45105  0.44
2019 Sun L, Fazal FM, Li P, Broughton JP, Lee B, Tang L, Huang W, Kool ET, Chang HY, Zhang QC. RNA structure maps across mammalian cellular compartments. Nature Structural & Molecular Biology. PMID 30886404 DOI: 10.1038/s41594-019-0200-7  1
2019 Van Gool F, Nguyen MLT, Mumbach MR, Satpathy AT, Rosenthal WL, Giacometti S, Le DT, Liu W, Brusko TM, Anderson MS, Rudensky AY, Marson A, Chang HY, Bluestone JA. A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells. Immunity. PMID 30709738 DOI: 10.1016/j.immuni.2018.12.016  0.36
2019 Li L, Wang Y, Torkelson JL, Shankar G, Pattison JM, Zhen HH, Fang F, Duren Z, Xin J, Gaddam S, Melo SP, Piekos SN, Li J, Liaw EJ, Chen L, ... ... Chang HY, et al. TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment. Cell Stem Cell. PMID 30686763 DOI: 10.1016/j.stem.2018.12.012  0.4
2019 Ang CE, Ma Q, Wapinski OL, Fan S, Flynn RA, Lee QY, Coe B, Onoguchi M, Olmos VH, Do BT, Dukes-Rimsky L, Xu J, Tanabe K, Wang L, Elling U, ... ... Chang HY, et al. The novel lncRNA is pro-neurogenic and mutated in human neurodevelopmental disorders. Elife. 8. PMID 30628890 DOI: 10.7554/eLife.41770  0.44
2018 Rubin AJ, Parker KR, Satpathy AT, Qi Y, Wu B, Ong AJ, Mumbach MR, Ji AL, Kim DS, Cho SW, Zarnegar BJ, Greenleaf WJ, Chang HY, Khavari PA. Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks. Cell. PMID 30580963 DOI: 10.1016/j.cell.2018.11.022  0.44
2018 Lu Z, Chang HY. The RNA Base-Pairing Problem and Base-Pairing Solutions. Cold Spring Harbor Perspectives in Biology. 10. PMID 30510063 DOI: 10.1101/cshperspect.a034926  1
2018 Pattison JM, Melo SP, Piekos SN, Torkelson JL, Bashkirova E, Mumbach MR, Rajasingh C, Zhen HH, Li L, Liaw E, Alber D, Rubin AJ, Shankar G, Bao X, Chang HY, et al. Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment. Nature Genetics. PMID 30397335 DOI: 10.1038/s41588-018-0263-0  0.32
2018 Chen X, Litzenburger UM, Wei Y, Schep AN, LaGory EL, Choudhry H, Giaccia AJ, Greenleaf WJ, Chang HY. Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity. Nature Communications. 9: 4590. PMID 30389926 DOI: 10.1038/s41467-018-07115-y  0.44
2018 Corces MR, Granja JM, Shams S, Louie BH, Seoane JA, Zhou W, Silva TC, Groeneveld C, Wong CK, Cho SW, Satpathy AT, Mumbach MR, Hoadley KA, Robertson AG, Sheffield NC, ... ... Chang HY, et al. The chromatin accessibility landscape of primary human cancers. Science (New York, N.Y.). 362. PMID 30361341 DOI: 10.1126/science.aav1898  0.44
2018 Ransom RC, Carter AC, Salhotra A, Leavitt T, Marecic O, Murphy MP, Lopez ML, Wei Y, Marshall CD, Shen EZ, Jones RE, Sharir A, Klein OD, Chan CKF, Wan DC, ... Chang HY, et al. Mechanoresponsive stem cells acquire neural crest fate in jaw regeneration. Nature. PMID 30356216 DOI: 10.1038/s41586-018-0650-9  0.52
2018 Jeng MY, Mumbach MR, Granja JM, Satpathy AT, Chang HY, Chang ALS. Enhancer connectome nominates target genes of inherited risk variants from inflammatory skin disorders. The Journal of Investigative Dermatology. PMID 30315781 DOI: 10.1016/j.jid.2018.09.011  0.44
2018 Chan CKF, Gulati GS, Sinha R, Tompkins JV, Lopez M, Carter AC, Ransom RC, Reinisch A, Wearda T, Murphy M, Brewer RE, Koepke LS, Marecic O, Manjunath A, Seo EY, ... ... Chang HY, et al. Identification of the Human Skeletal Stem Cell. Cell. 175: 43-56.e21. PMID 30241615 DOI: 10.1016/j.cell.2018.07.029  0.52
2018 Chu C, Chang HY. ChIRP-MS: RNA-Directed Proteomic Discovery. Methods in Molecular Biology (Clifton, N.J.). 1861: 37-45. PMID 30218357 DOI: 10.1007/978-1-4939-8766-5_3  0.6
2018 Duren Z, Chen X, Zamanighomi M, Zeng W, Satpathy AT, Chang HY, Wang Y, Wong WH. Integrative analysis of single-cell genomics data by coupled nonnegative matrix factorizations. Proceedings of the National Academy of Sciences of the United States of America. PMID 29987051 DOI: 10.1073/pnas.1805681115  0.36
2018 Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo F, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, ... ... Chang HY, et al. Retraction Note: DDX5 and its associated lncRNA Rmrp modulate T17 cell effector functions. Nature. PMID 29973715 DOI: 10.1038/s41586-018-0311-z  0.4
2018 Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, ... ... Chang HY, et al. Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. PMID 29899441 DOI: 10.1038/s41586-018-0227-7  0.44
2018 Chen L, Roake CM, Freund A, Batista PJ, Tian S, Yin YA, Gajera CR, Lin S, Lee B, Pech MF, Venteicher AS, Das R, Chang HY, Artandi SE. An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1. Cell. PMID 29804836 DOI: 10.1016/j.cell.2018.04.039  0.96
2018 Satpathy AT, Brown RA, Gomulia E, Briseño CG, Mumbach MR, Pan Z, Murphy KM, Natkunam Y, Chang HY, Kim J. Expression of the transcription factor ZBTB46 distinguishes human histiocytic disorders of classical dendritic cell origin. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 29743654 DOI: 10.1038/s41379-018-0052-4  0.36
2018 Cho SW, Xu J, Sun R, Mumbach MR, Carter AC, Chen YG, Yost KE, Kim J, He J, Nevins SA, Chin SF, Caldas C, Liu SJ, Horlbeck MA, Lim DA, ... ... Chang HY, et al. Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. Cell. PMID 29731168 DOI: 10.1016/j.cell.2018.03.068  0.52
2018 Yost KE, Carter AC, Xu J, Litzenburger U, Chang HY. ATAC Primer Tool for targeted analysis of accessible chromatin. Nature Methods. 15: 304-305. PMID 29702633 DOI: 10.1038/nmeth.4663  0.52
2018 Wang KC, Chang HY. Epigenomics: Technologies and Applications. Circulation Research. 122: 1191-1199. PMID 29700067 DOI: 10.1161/CIRCRESAHA.118.310998  0.76
2018 Satpathy AT, Saligrama N, Buenrostro JD, Wei Y, Wu B, Rubin AJ, Granja JM, Lareau CA, Li R, Qi Y, Parker KR, Mumbach MR, Serratelli WS, Gennert DG, Schep AN, ... ... Chang HY, et al. Transcript-indexed ATAC-seq for precision immune profiling. Nature Medicine. PMID 29686426 DOI: 10.1038/s41591-018-0008-8  0.44
2018 Calo E, Gu B, Bowen ME, Aryan F, Zalc A, Liang J, Flynn RA, Swigut T, Chang HY, Attardi LD, Wysocka J. Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders. Nature. PMID 29364875 DOI: 10.1038/nature25449  0.4
2017 Carter AC, Chang HY, Church G, Dombkowski A, Ecker JR, Gil E, Giresi PG, Greely H, Greenleaf WJ, Hacohen N, He C, Hill D, Ko J, Kohane I, Kundaje A, et al. Challenges and recommendations for epigenomics in precision health. Nature Biotechnology. 35: 1128-1132. PMID 29220033 DOI: 10.1038/nbt.4030  0.52
2017 Bailey AS, Batista PJ, Gold RS, Chen YG, de Rooij DG, Chang HY, Fuller MT. The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline. Elife. 6. PMID 29087293 DOI: 10.7554/eLife.26116  0.96
2017 Wapinski OL, Lee QY, Chen AC, Li R, Corces MR, Ang CE, Treutlein B, Xiang C, Baubet V, Suchy FP, Sankar V, Sim S, Quake SR, Dahmane N, Wernig M, ... Chang HY, et al. Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons. Cell Reports. 20: 3236-3247. PMID 28954238 DOI: 10.1016/j.celrep.2017.09.011  0.4
2017 Lu Z, Carter AC, Chang HY. Mechanistic insights in X-chromosome inactivation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28947655 DOI: 10.1098/rstb.2016.0356  1
2017 Mumbach MR, Satpathy AT, Boyle EA, Dai C, Gowen BG, Cho SW, Nguyen ML, Rubin AJ, Granja JM, Kazane KR, Wei Y, Nguyen T, Greenside PG, Corces MR, Tycko J, ... ... Chang HY, et al. Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements. Nature Genetics. PMID 28945252 DOI: 10.1038/ng.3963  0.44
2017 Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, ... ... Chang HY, et al. Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. PMID 28854172 DOI: 10.1038/nature23875  0.44
2017 Corces MR, Trevino AE, Hamilton EG, Greenside PG, Sinnott-Armstrong NA, Vesuna S, Satpathy AT, Rubin AJ, Montine KS, Wu B, Kathiria A, Cho SW, Mumbach MR, Carter AC, Kasowski M, ... ... Chang HY, et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nature Methods. PMID 28846090 DOI: 10.1038/nmeth.4396  0.52
2017 Chen YG, Satpathy AT, Chang HY. Gene regulation in the immune system by long noncoding RNAs. Nature Immunology. 18: 962-972. PMID 28829444 DOI: 10.1038/ni.3771  0.36
2017 Rubin AJ, Barajas BC, Furlan-Magaril M, Lopez-Pajares V, Mumbach MR, Howard I, Kim DS, Boxer LD, Cairns J, Spivakov M, Wingett SW, Shi M, Zhao Z, Greenleaf WJ, Kundaje A, ... ... Chang HY, et al. Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation. Nature Genetics. PMID 28805829 DOI: 10.1038/ng.3935  0.32
2017 Li HB, Tong J, Zhu S, Batista PJ, Duffy EE, Zhao J, Bailis W, Cao G, Kroehling L, Chen Y, Wang G, Broughton JP, Chen YG, Kluger Y, Simon MD, ... Chang HY, et al. m(6)A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways. Nature. PMID 28792938 DOI: 10.1038/nature23450  0.96
2017 Liu Q, Jiang C, Xu J, Zhao M, Van Bortle K, Cheng X, Wang G, Chang HY, Wu JC, Snyder MP. Genome-Wide Temporal Profiling of Transcriptome and Open-Chromatin of Early Cardiomyocyte Differentiation Derived From hiPSCs and hESCs. Circulation Research. PMID 28663367 DOI: 10.1161/CIRCRESAHA.116.310456  0.44
2017 Wang KC, Chang HY. Transcription coactivator and lncRNA duet evoke Hox genes. Plos Genetics. 13: e1006797. PMID 28662057 DOI: 10.1371/journal.pgen.1006797  0.76
2017 Chen YG, Kim MV, Chen X, Batista PJ, Aoyama S, Wilusz JE, Iwasaki A, Chang HY. Sensing Self and Foreign Circular RNAs by Intron Identity. Molecular Cell. PMID 28625551 DOI: 10.1016/j.molcel.2017.05.022  0.96
2017 Simsek D, Tiu GC, Flynn RA, Byeon GW, Leppek K, Xu AF, Chang HY, Barna M. The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity. Cell. 169: 1051-1065.e18. PMID 28575669 DOI: 10.1016/j.cell.2017.05.022  0.4
2017 Xu J, Carter AC, Gendrel AV, Attia M, Loftus J, Greenleaf WJ, Tibshirani R, Heard E, Chang HY. Corrigendum: Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells. Nature Genetics. 49: 970. PMID 28546577 DOI: 10.1038/ng0617-970a  0.52
2017 Chang J, Mancuso MR, Maier C, Liang X, Yuki K, Yang L, Kwong JW, Wang J, Rao V, Vallon M, Kosinski C, Zhang JJ, Mah AT, Xu L, Li L, ... ... Chang HY, et al. Gpr124 is essential for blood-brain barrier integrity in central nervous system disease. Nature Medicine. PMID 28288111 DOI: 10.1038/nm.4309  0.4
2017 Schmitt AM, Chang HY. Long Noncoding RNAs: At the Intersection of Cancer and Chromatin Biology. Cold Spring Harbor Perspectives in Medicine. PMID 28193769 DOI: 10.1101/cshperspect.a026492  0.64
2017 Xu J, Carter AC, Gendrel AV, Attia M, Loftus J, Greenleaf WJ, Tibshirani R, Heard E, Chang HY. Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells. Nature Genetics. PMID 28112738 DOI: 10.1038/ng.3769  0.52
2016 Liu SJ, Horlbeck MA, Cho SW, Birk HS, Malatesta M, He D, Attenello FJ, Villalta JE, Cho MY, Chen Y, Mandegar MA, Olvera MP, Gilbert LA, Conklin BR, Chang HY, et al. CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science (New York, N.Y.). PMID 27980086 DOI: 10.1126/science.aah7111  0.32
2016 Li L, Helms JA, Chang HY. Comment on "Hotair Is Dispensable for Mouse Development". Plos Genetics. 12: e1006406. PMID 27977686 DOI: 10.1371/journal.pgen.1006406  0.48
2016 Lee B, Flynn RA, Kadina A, Guo JK, Kool ET, Chang HY. Comparison of SHAPE Reagents for Mapping RNA Structures Inside Living Cells. Rna (New York, N.Y.). PMID 27879433 DOI: 10.1261/rna.058784.116  0.44
2016 Xu J, Spitale RC, Guan L, Flynn RA, Torre EA, Li R, Raber I, Qu K, Kern D, Knaggs HE, Chang HY, Chang AL. Novel Gene Expression Profile of Women with Intrinsic Skin Youthfulness by Whole Transcriptome Sequencing. Plos One. 11: e0165913. PMID 27829007 DOI: 10.1371/journal.pone.0165913  0.6
2016 Chen X, Shen Y, Draper W, Buenrostro JD, Litzenburger U, Cho SW, Satpathy AT, Carter AC, Ghosh RP, East-Seletsky A, Doudna JA, Greenleaf WJ, Liphardt JT, Chang HY. ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing. Nature Methods. PMID 27749837 DOI: 10.1038/nmeth.4031  0.52
2016 Fazal FM, Chang HY. lncRNA Structure: Message to the Heart. Molecular Cell. 64: 1-2. PMID 27716479 DOI: 10.1016/j.molcel.2016.09.030  1
2016 Huang WH, Guenthner CJ, Xu J, Nguyen T, Schwarz LA, Wilkinson AW, Gozani O, Chang HY, Shamloo M, Luo L. Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome. Neuron. PMID 27693255 DOI: 10.1016/j.neuron.2016.09.019  0.44
2016 Schmitt AM, Garcia JT, Hung T, Flynn RA, Shen Y, Qu K, Payumo AY, Peres-da-Silva A, Broz DK, Baum R, Guo S, Chen JK, Attardi LD, Chang HY. An inducible long noncoding RNA amplifies DNA damage signaling. Nature Genetics. PMID 27668660 DOI: 10.1038/ng.3673  1
2016 Chu C, Chang HY. Understanding RNA-Chromatin Interactions Using Chromatin Isolation by RNA Purification (ChIRP). Methods in Molecular Biology (Clifton, N.J.). 1480: 115-23. PMID 27659979 DOI: 10.1007/978-1-4939-6380-5_10  0.6
2016 Mumbach MR, Rubin AJ, Flynn RA, Dai C, Khavari PA, Greenleaf WJ, Chang HY. HiChIP: efficient and sensitive analysis of protein-directed genome architecture. Nature Methods. PMID 27643841 DOI: 10.1038/nmeth.3999  0.4
2016 Corces MR, Buenrostro JD, Wu B, Greenside PG, Chan SM, Koenig JL, Snyder MP, Pritchard JK, Kundaje A, Greenleaf WJ, Majeti R, Chang HY. Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution. Nature Genetics. PMID 27526324 DOI: 10.1038/ng.3646  1
2016 Wang K, Lee CS, Marinkovich MP, Chang HY, Oro AE, Khavari PA. Factors That May Promote an Effective Local Research Environment. The Journal of Investigative Dermatology. 136: 1529-31. PMID 27450496 DOI: 10.1016/j.jid.2016.04.015  0.32
2016 Giorgetti L, Lajoie BR, Carter AC, Attia M, Zhan Y, Xu J, Chen CJ, Kaplan N, Chang HY, Heard E, Dekker J. Structural organization of the inactive X chromosome in the mouse. Nature. PMID 27437574 DOI: 10.1038/nature18589  0.52
2016 Atianand MK, Hu W, Satpathy AT, Shen Y, Ricci EP, Alvarez-Dominguez JR, Bhatta A, Schattgen SA, McGowan JD, Blin J, Braun JE, Gandhi P, Moore MJ, Chang HY, Lodish HF, et al. A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation. Cell. 165: 1672-85. PMID 27315481 DOI: 10.1016/j.cell.2016.05.075  0.36
2016 Sadik H, Korangath P, Nguyen N, Győrffy B, Kumar R, Hedayati M, Teo WW, Park S, Panday H, Gonzalez Munoz T, Menyhart O, Shah N, Pandita RK, Chang JC, DeWeese TL, ... Chang HY, et al. HOXC10 expression supports the development of chemotherapy resistance by fine tuning DNA repair in breast cancer cells. Cancer Research. PMID 27302171 DOI: 10.1158/0008-5472.CAN-16-0774  1
2016 Lu Z, Zhang QC, Lee B, Flynn RA, Smith MA, Robinson JT, Davidovich C, Gooding AR, Goodrich KJ, Mattick JS, Mesirov JP, Cech TR, Chang HY. RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure. Cell. PMID 27180905 DOI: 10.1016/j.cell.2016.04.028  1
2016 Arda HE, Li L, Tsai J, Torre EA, Rosli Y, Peiris H, Spitale RC, Dai C, Gu X, Qu K, Wang P, Wang J, Grompe M, Scharfmann R, Snyder MS, ... ... Chang HY, et al. Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function. Cell Metabolism. PMID 27133132 DOI: 10.1016/j.cmet.2016.04.002  1
2016 Zarnegar BJ, Flynn RA, Shen Y, Do BT, Chang HY, Khavari PA. irCLIP platform for efficient characterization of protein-RNA interactions. Nature Methods. PMID 27111506 DOI: 10.1038/nmeth.3840  0.4
2016 Ma Q, Chang HY. Single-cell profiling of lncRNAs in the developing human brain. Genome Biology. 17: 68. PMID 27079200 DOI: 10.1186/s13059-016-0933-0  1
2016 Schmitt AM, Chang HY. Long Noncoding RNAs in Cancer Pathways. Cancer Cell. 29: 452-63. PMID 27070700 DOI: 10.1016/j.ccell.2016.03.010  1
2016 Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, ... ... Chang HY, et al. Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. Molecular Cell. 62: 34-46. PMID 27058786 DOI: 10.1016/j.molcel.2016.03.013  1
2016 Oh S, Flynn RA, Floor SN, Purzner J, Martin L, Do BT, Schubert S, Vaka D, Morrissy S, Li Y, Kool M, Hovestadt V, Jones DT, Northcott PA, Risch T, ... ... Chang HY, et al. Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress. Oncotarget. 7: 28169-82. PMID 27058758 DOI: 10.18632/oncotarget.8612  1
2016 Lu Z, Chang HY. Decoding the RNA structurome. Current Opinion in Structural Biology. 36: 142-148. PMID 26923056 DOI: 10.1016/j.sbi.2016.01.007  1
2016 He C, Hu H, Wilson KD, Wu H, Feng J, Xia S, Churko J, Qu K, Chang HY, Wu JC. Systematic Characterization of Long Non-Coding RNAs Reveals the Contrasting Coordination of Cis- and Trans- Molecular Regulation in Human Fetal and Adult Heart. Circulation. Cardiovascular Genetics. PMID 26896382 DOI: 10.1161/CIRCGENETICS.115.001264  1
2016 Flynn RA, Do BT, Rubin AJ, Calo E, Lee B, Kuchelmeister H, Rale M, Chu C, Kool ET, Wysocka J, Khavari PA, Chang HY. 7SK-BAF axis controls pervasive transcription at enhancers. Nature Structural & Molecular Biology. PMID 26878240 DOI: 10.1038/nsmb.3176  0.6
2016 Lin WC, Chang HY, Chen JY. Electrotransfer of the tilapia piscidin 3 and tilapia piscidin 4 genes into skeletal muscle enhances the antibacterial and immunomodulatory functions of Oreochromis niloticus. Fish & Shellfish Immunology. PMID 26828260 DOI: 10.1016/j.fsi.2016.01.034  0.4
2016 Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo F, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, ... ... Chang HY, et al. Corrigendum: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions. Nature. PMID 26789242 DOI: 10.1038/nature16968  0.4
2016 Chang HY, Chen CT, Lih TM, Lynn KS, Juo CG, Hsu WL, Sung TY. iMet-Q: A User-Friendly Tool for Label-Free Metabolomics Quantitation Using Dynamic Peak-Width Determination. Plos One. 11: e0146112. PMID 26784691 DOI: 10.1371/journal.pone.0146112  0.4
2016 Qu K, Garamszegi S, Wu F, Thorvaldsdottir H, Liefeld T, Ocana M, Borges-Rivera D, Pochet N, Robinson JT, Demchak B, Hull T, Ben-Artzi G, Blankenberg D, Barber GP, Lee BT, ... ... Chang HY, et al. Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace. Nature Methods. PMID 26780094 DOI: 10.1038/nmeth.3732  0.52
2016 Quinn JJ, Zhang QC, Georgiev P, Ilik IA, Akhtar A, Chang HY. Rapid evolutionary turnover underlies conserved lncRNA-genome interactions. Genes & Development. 30: 191-207. PMID 26773003 DOI: 10.1101/gad.272187.115  1
2016 Chang HY, Chang TC, Huang WY, Lee CT, Yen CJ, Tsai YS, Tzai TS, Chen SH, Chow NH. RON nuclear translocation under hypoxia potentiated chemoresistance to DNA double-strand break-inducing anti-cancer drugs. Molecular Cancer Therapeutics. PMID 26772202 DOI: 10.1158/1535-7163.MCT-15-0311  0.32
2016 Flynn RA, Zhang QC, Spitale RC, Lee B, Mumbach MR, Chang HY. Transcriptome-wide interrogation of RNA secondary structure in living cells with icSHAPE. Nature Protocols. 11: 273-90. PMID 26766114 DOI: 10.1038/nprot.2016.011  1
2016 Wan Y, Qu K, Ouyang Z, Chang HY. Genome-Wide Probing of RNA Structures In Vitro Using Nucleases and Deep Sequencing. Methods in Molecular Biology (Clifton, N.J.). 1361: 141-60. PMID 26483021 DOI: 10.1007/978-1-4939-3079-1_9  0.36
2016 Hsiao PJ, Chen GH, Chang YH, Chang CH, Chang H, Bai LY. An unresectable retroperitoneal malignant fibrous histiocytoma: A case report Oncology Letters. 11: 2403-2407. DOI: 10.3892/ol.2016.4283  0.44
2016 Chang HY, Lee AYP. The relationship between business diversification and productivity: considering the impact of process innovation at different corporate life cycles Technology Analysis and Strategic Management. 1-14. DOI: 10.1080/09537325.2016.1158405  0.32
2016 Tsay CY, Lin YH, Wang YM, Chang HY, Lei CM, Jen SU. Electrical transport properties of CoMn0.2-xGaxFe1.8O4 ferrites using complex impedance spectroscopy Aip Advances. 6. DOI: 10.1063/1.4943149  0.6
2015 Bao X, Rubin AJ, Qu K, Zhang J, Giresi PG, Chang HY, Khavari PA. A novel ATAC-seq approach reveals lineage-specific reinforcement of the open chromatin landscape via cooperation between BAF and p63. Genome Biology. 16: 284. PMID 26683334 DOI: 10.1186/s13059-015-0840-9  0.4
2015 Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo FW, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, ... ... Chang HY, et al. DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions. Nature. PMID 26675721 DOI: 10.1038/nature16193  0.4
2015 Quinn JJ, Chang HY. Unique features of long non-coding RNA biogenesis and function. Nature Reviews. Genetics. 17: 47-62. PMID 26666209 DOI: 10.1038/nrg.2015.10  1
2015 Carlson HL, Quinn JJ, Yang YW, Thornburg CK, Chang HY, Stadler HS. LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes. Plos Genetics. 11: e1005680. PMID 26633036 DOI: 10.1371/journal.pgen.1005680  0.32
2015 Mazumdar C, Shen Y, Xavy S, Zhao F, Reinisch A, Li R, Corces MR, Flynn RA, Buenrostro JD, Chan SM, Thomas D, Koenig JL, Hong WJ, Chang HY, Majeti R. Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation. Cell Stem Cell. PMID 26607380 DOI: 10.1016/j.stem.2015.09.017  0.4
2015 Li CT, Chang HY, Li YY, Huang YJ, Tsai YL, Vittal R, Sheng YJ, Ho KC. Electro-catalytic Zinc Composites as the Efficient Counter Electrodes of Dye-Sensitized Solar Cells: A Study on the Electrochemical Performances and Density Functional Theory Calculations. Acs Applied Materials & Interfaces. PMID 26599619 DOI: 10.1021/acsami.5b07724  0.44
2015 Chang HY, Huang CW, Chen YF, Chen SY, Sheng YJ, Tsao HK. Assembly of Lock and Key Colloids Mediated by Polymeric Depletant. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 26566068 DOI: 10.1021/acs.langmuir.5b02527  0.44
2015 Choong WK, Chang HY, Chen CT, Tsai CF, Hsu WL, Chen YJ, Sung TY. Informatics view on the challenges of identifying missing proteins from shotgun proteomics. Journal of Proteome Research. PMID 26549055 DOI: 10.1021/acs.jproteome.5b00482  0.4
2015 Jim WT, Chiu NC, Ho CS, Shu CH, Chang JH, Hung HY, Kao HA, Chang HY, Peng CC, Yui BH, Chuu CP. Outcome of Preterm Infants With Postnatal Cytomegalovirus Infection via Breast Milk: A Two-Year Prospective Follow-Up Study. Medicine. 94: e1835. PMID 26512588 DOI: 10.1097/MD.0000000000001835  0.44
2015 Lee YC, Lin SW, Chen MY, Chang SY, Kuo CH, Sheng WH, Hsieh SM, Sun HY, Chang HY, Wu MR, Liu WC, Wu PY, Yang SP, Zhang JY, Su YC, et al. Presence of Tablet Remnants of Nevirapine Extended-Release in Stools and Its Impact on Virological Outcome in HIV-1-Infected Patients: A Prospective Cohort Study. Plos One. 10: e0140574. PMID 26465325 DOI: 10.1371/journal.pone.0140574  0.4
2015 Chou HC, Wang YM, Chang HY. Design intelligent wheelchair with ECG measurement and wireless transmission function. Technology and Health Care : Official Journal of the European Society For Engineering and Medicine. PMID 26444818 DOI: 10.3233/THC-151092  0.6
2015 Spitale RC, Flynn RA, Zhang QC, Crisalli P, Lee B, Jung JW, Kuchelmeister HY, Batista PJ, Torre EA, Kool ET, Chang HY. Erratum: Structural imprints in vivo decode RNA regulatory mechanisms. Nature. PMID 26416736 DOI: 10.1038/nature15717  0.96
2015 Zhao FR, Zhou DH, Shao JJ, Lin T, Zhang YG, Chang HY. Avian influenza and live mixed poultry-animal markets in China. The Journal of Infection. PMID 26327234 DOI: 10.1016/j.jinf.2015.08.006  0.32
2015 Chiang CY, Pan CC, Chang HY, Lai MD, Tzai TS, Tsai YS, Ling P, Liu HS, Lee BF, Cheng HL, Ho CL, Chen SH, Chow NH. SH3BGRL3 Protein As A Potential Prognostic Biomarker For Urothelial Carcinoma: A novel binding partner of epidermal growth factor receptor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26286913 DOI: 10.1158/1078-0432.CCR-14-3308  0.32
2015 Qu K, Zaba LC, Giresi PG, Li R, Longmire M, Kim YH, Greenleaf WJ, Chang HY. Individuality and variation of personal regulomes in primary human T cells. Cell Systems. 1: 51-61. PMID 26251845 DOI: 10.1016/j.cels.2015.06.003  1
2015 Chang HY, Liao CY, Su GC, Lin SW, Wang HW, Chi P. Functional Relationship of ATP Hydrolysis, Presynaptic Filament Stability, and Homologous DNA Pairing Activity of the Human Meiotic Recombinase DMC1. The Journal of Biological Chemistry. PMID 26088134 DOI: 10.1074/jbc.M115.666289  0.32
2015 Roost C, Lynch SR, Batista PJ, Qu K, Chang HY, Kool ET. Correction to "Structure and Thermodynamics of N(6)-Methyladenosine in RNA: A Spring-Loaded Base Modification". Journal of the American Chemical Society. PMID 26087989 DOI: 10.1021/jacs.5b05858  1
2015 Buenrostro JD, Wu B, Litzenburger UM, Ruff D, Gonzales ML, Snyder MP, Chang HY, Greenleaf WJ. Single-cell chromatin accessibility reveals principles of regulatory variation. Nature. 523: 486-90. PMID 26083756 DOI: 10.1038/nature14590  1
2015 Chen CL, Chen FF, Lin CH, Lou SZ, Chang HY, Yeung KT. Effect of Anterior Ankle-Foot Orthoses on Weight Shift in Persons With Stroke. Archives of Physical Medicine and Rehabilitation. PMID 25998222 DOI: 10.1016/j.apmr.2015.05.003  0.44
2015 Satpathy AT, Chang HY. Long noncoding RNA in hematopoiesis and immunity. Immunity. 42: 792-804. PMID 25992856 DOI: 10.1016/j.immuni.2015.05.004  1
2015 Lin CH, Lin CT, Huang HT, Zeng WS, Chiang SC, Chang HY. 60-GHz optical/wireless MIMO system integrated with optical subcarrier multiplexing and 2x2 wireless communication. Optics Express. 23: 12111-6. PMID 25969299  0.44
2015 Chung SY, Kao CH, Villarroya F, Chang HY, Chang HC, Hsiao SP, Liou GG, Chen SL. Bhlhe40 Represses PGC-1α Activity on Metabolic Gene Promoters in Myogenic Cells. Molecular and Cellular Biology. 35: 2518-29. PMID 25963661 DOI: 10.1128/MCB.00387-15  0.32
2015 Zhao FR, Zhou DH, Zhang YG, Shao JJ, Lin T, Li YF, Wei P, Chang HY. Detection prevalence of H5N1 avian influenza virus among stray cats in eastern China. Journal of Medical Virology. 87: 1436-40. PMID 25952001 DOI: 10.1002/jmv.24216  0.32
2015 Wang RS, Chang HY, Kao SH, Kao CH, Wu YC, Yeh S, Tzeng CR, Chang C. Abnormal mitochondrial function and impaired granulosa cell differentiation in androgen receptor knockout mice. International Journal of Molecular Sciences. 16: 9831-49. PMID 25941928 DOI: 10.3390/ijms16059831  0.32
2015 Sheen JM, Yu HR, Tiao MM, Chen CC, Huang LT, Chang HY, Tain YL. Prenatal dexamethasone-induced programmed hypertension and renal programming. Life Sciences. 132: 41-8. PMID 25921765 DOI: 10.1016/j.lfs.2015.04.005  0.56
2015 Chang HY, Huang MF, Hsu CL, Huang CC, Chang HT. Analyses of functional polymer-modified nanoparticles for protein sensing by surface-assisted laser desorption/ionization mass spectrometry coupled with HgTe nanomatrices. Colloids and Surfaces. B, Biointerfaces. 130: 157-63. PMID 25896538 DOI: 10.1016/j.colsurfb.2015.04.001  0.52
2015 Grow EJ, Flynn RA, Chavez SL, Bayless NL, Wossidlo M, Wesche DJ, Martin L, Ware CB, Blish CA, Chang HY, Pera RA, Wysocka J. Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells. Nature. 522: 221-5. PMID 25896322 DOI: 10.1038/nature14308  1
2015 Chu C, Zhang QC, da Rocha ST, Flynn RA, Bharadwaj M, Calabrese JM, Magnuson T, Heard E, Chang HY. Systematic discovery of Xist RNA binding proteins. Cell. 161: 404-16. PMID 25843628 DOI: 10.1016/j.cell.2015.03.025  1
2015 Spitale RC, Flynn RA, Zhang QC, Crisalli P, Lee B, Jung JW, Kuchelmeister HY, Batista PJ, Torre EA, Kool ET, Chang HY. Structural imprints in vivo decode RNA regulatory mechanisms. Nature. 519: 486-90. PMID 25799993 DOI: 10.1038/nature14263  1
2015 Gilchrest BA, Campisi J, Chang HY, Fisher GJ, Kulesz-Martin MF. Montagna Symposium 2014-skin aging: molecular mechanisms and tissue consequences. The Journal of Investigative Dermatology. 135: 950-3. PMID 25785950 DOI: 10.1038/jid.2014.546  1
2015 Zhao FR, Zhou DH, Lin T, Shao JJ, Wei P, Zhang YG, Chang HY. The first lack of evidence of H7N9 avian influenza virus infections among pigs in Eastern China. Microbial Pathogenesis. 80: 63-6. PMID 25680835 DOI: 10.1016/j.micpath.2015.02.003  0.32
2015 Cho SW, Chang HY. Genomics: CRISPR engineering turns on genes. Nature. 517: 560-2. PMID 25631441 DOI: 10.1038/517560a  1
2015 Corley M, Solem A, Qu K, Chang HY, Laederach A. Detecting riboSNitches with RNA folding algorithms: a genome-wide benchmark. Nucleic Acids Research. 43: 1859-68. PMID 25618847 DOI: 10.1093/nar/gkv010  1
2015 Roost C, Lynch SR, Batista PJ, Qu K, Chang HY, Kool ET. Structure and thermodynamics of N6-methyladenosine in RNA: a spring-loaded base modification. Journal of the American Chemical Society. 137: 2107-15. PMID 25611135 DOI: 10.1021/ja513080v  1
2015 Chu C, Spitale RC, Chang HY. Technologies to probe functions and mechanisms of long noncoding RNAs. Nature Structural & Molecular Biology. 22: 29-35. PMID 25565030 DOI: 10.1038/nsmb.2921  1
2015 Chung CJ, Chang CH, Chuu CP, Yang CR, Chang YH, Huang CP, Chen WC, Chung MC, Chang H. Reduced 5-methylcytosine level as a potential progression predictor in patients with T1 or non-invasive urothelial carcinoma. International Journal of Molecular Sciences. 16: 677-90. PMID 25561224 DOI: 10.3390/ijms16010677  0.44
2015 Chang HY, Li MH, Huang TC, Hsu CL, Tsai SR, Lee SC, Huang HC, Juan HF. Quantitative proteomics reveals middle infrared radiation-interfered networks in breast cancer cells. Journal of Proteome Research. 14: 1250-62. PMID 25556991 DOI: 10.1021/pr5011873  0.48
2015 Quinn JJ, Chang HY. In situ dissection of RNA functional subunits by domain-specific chromatin isolation by RNA purification (dChIRP). Methods in Molecular Biology (Clifton, N.J.). 1262: 199-213. PMID 25555583 DOI: 10.1007/978-1-4939-2253-6_12  1
2015 Lynn KS, Cheng ML, Chen YR, Hsu C, Chen A, Lih TM, Chang HY, Huang CJ, Shiao MS, Pan WH, Sung TY, Hsu WL. Metabolite identification for mass spectrometry-based metabolomics using multiple types of correlated ion information. Analytical Chemistry. 87: 2143-51. PMID 25543920 DOI: 10.1021/ac503325c  0.32
2015 Calo E, Flynn RA, Martin L, Spitale RC, Chang HY, Wysocka J. RNA helicase DDX21 coordinates transcription and ribosomal RNA processing. Nature. 518: 249-53. PMID 25470060 DOI: 10.1038/nature13923  1
2015 Flynn RA, Martin L, Spitale RC, Do BT, Sagan SM, Zarnegar B, Qu K, Khavari PA, Quake SR, Sarnow P, Chang HY. Dissecting noncoding and pathogen RNA-protein interactomes. Rna (New York, N.Y.). 21: 135-43. PMID 25411354 DOI: 10.1261/rna.047803.114  1
2015 Wang RS, Chang HY, Kao SH, Kao CH, Wu YC, Yeh S, Tzeng CR, Chang C. Abnormal mitochondrial function and impaired granulosa cell differentiation in androgen receptor knockout mice International Journal of Molecular Sciences. 16: 9831-9849. DOI: 10.3390/ijms16059831  0.32
2015 Chang HY, Lin CH, Liu YC, Li WP, Wang YC. A 2.5 GHz High Efficiency High Power Low Phase Noise Monolithic Microwave Power Oscillator Ieee Microwave and Wireless Components Letters. DOI: 10.1109/LMWC.2015.2479849  0.44
2015 Chen SF, Chang HY, Wang SJ, Chen SH, Chen CC. Enhanced electromagnetic properties of Fe-Cr-Si alloy powders by sodium silicate treatment Journal of Alloys and Compounds. 637: 30-35. DOI: 10.1016/j.jallcom.2015.02.198  0.56
2015 Chang HY, Wang CY, Lee MH, Wu HK, Liang JC, Lee SWY, Chiou GL, Lo HC, Lin JW, Hsu CY, Wu YT, Chen S, Hwang FK, Tsai CC. A review of features of technology-supported learning environments based on participants' perceptions Computers in Human Behavior. 53: 223-237. DOI: 10.1016/j.chb.2015.06.042  0.32
2015 Shen J, Liu OL, Chang HY. Assessing Students’ Deep Conceptual Understanding in Physical Sciences: an Example on Sinking and Floating International Journal of Science and Mathematics Education. DOI: 10.1007/s10763-015-9680-z  0.32
2015 Chen WY, Chang HY, Lu JK, Huang YC, Harroun SG, Tseng YT, Li YJ, Huang CC, Chang HT. Self-Assembly of Antimicrobial Peptides on Gold Nanodots: Against Multidrug-Resistant Bacteria and Wound-Healing Application Advanced Functional Materials. 25: 7189-7199. DOI: 10.1002/adfm.201503248  0.52
2014 Paik KJ, Qu K, Hsueh B, Torre EA, Flynn RA, Chung MT, Spencley A, Wang KC, Wu JC, Longaker MT, Chang HY, Wan DC. Abstract 158: Identification of BMP-Responsive Long Noncoding RNAs in Pluripotent Cells. Plastic and Reconstructive Surgery. 133: 174. PMID 25942268 DOI: 10.1097/01.prs.0000444987.90678.b2  0.76
2014 Chen CH, Wang PH, Hsieh MT, Tzeng CR, Wu YH, Lee CS, Chu YH, Chang HY. Sexual orientations of women with polycystic ovary syndrome: clinical observation in Taiwan. Taiwanese Journal of Obstetrics & Gynecology. 53: 542-6. PMID 25510698 DOI: 10.1016/j.tjog.2014.09.002  0.32
2014 Batista PJ, Molinie B, Wang J, Qu K, Zhang J, Li L, Bouley DM, Lujan E, Haddad B, Daneshvar K, Carter AC, Flynn RA, Zhou C, Lim KS, Dedon P, ... ... Chang HY, et al. m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells. Cell Stem Cell. 15: 707-19. PMID 25456834 DOI: 10.1016/j.stem.2014.09.019  1
2014 Chang HY, Huang TC, Chen NN, Huang HC, Juan HF. Combination therapy targeting ectopic ATP synthase and 26S proteasome induces ER stress in breast cancer cells. Cell Death & Disease. 5: e1540. PMID 25429617 DOI: 10.1038/cddis.2014.504  0.32
2014 Chang CC, Ting CT, Chang CH, Fang S, Chang HY. The persistence of facultative parthenogenesis in Drosophila albomicans. Plos One. 9: e113275. PMID 25415200 DOI: 10.1371/journal.pone.0113275  0.44
2014 Benitez CM, Qu K, Sugiyama T, Pauerstein PT, Liu Y, Tsai J, Gu X, Ghodasara A, Arda HE, Zhang J, Dekker JD, Tucker HO, Chang HY, Kim SK. An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development. Plos Genetics. 10: e1004645. PMID 25330008 DOI: 10.1371/journal.pgen.1004645  1
2014 Juang JH, Kuo CH, Liu YH, Chang HY, Chen CT. Effects of Dipeptidyl Peptidase-4 Inhibition with MK-0431 on Syngeneic Mouse Islet Transplantation. International Journal of Endocrinology. 2014: 795283. PMID 25165473 DOI: 10.1155/2014/795283  0.4
2014 Quinn JJ, Chang HY. RNA switch at enhancers. Nature Genetics. 46: 929-31. PMID 25162802 DOI: 10.1038/ng.3074  1
2014 Ding YZ, You YN, Sun DJ, Chen HT, Wang YL, Chang HY, Pan L, Fang YZ, Zhang ZW, Zhou P, Lv JL, Liu XS, Shao JJ, Zhao FR, Lin T, et al. The effects of the context-dependent codon usage bias on the structure of the nsp1α of porcine reproductive and respiratory syndrome virus. Biomed Research International. 2014: 765320. PMID 25162025 DOI: 10.1155/2014/765320  0.32
2014 Spitale RC, Flynn RA, Torre EA, Kool ET, Chang HY. RNA structural analysis by evolving SHAPE chemistry. Wiley Interdisciplinary Reviews. Rna. 5: 867-81. PMID 25132067 DOI: 10.1002/wrna.1253  1
2014 Juang JH, Kuo CH, Liu YH, Chang HY, Van YH. Effects of all-trans retinoid acid and exendin-4 on islet transplantation in NOD mice. Transplantation Proceedings. 46: 1950-2. PMID 25131079 DOI: 10.1016/j.transproceed.2014.05.072  0.4
2014 Li L, Chang HY. Physiological roles of long noncoding RNAs: insight from knockout mice. Trends in Cell Biology. 24: 594-602. PMID 25022466 DOI: 10.1016/j.tcb.2014.06.003  1
2014 Quinn JJ, Ilik IA, Qu K, Georgiev P, Chu C, Akhtar A, Chang HY. Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification. Nature Biotechnology. 32: 933-40. PMID 24997788 DOI: 10.1038/nbt.2943  1
2014 Zheng GX, Do BT, Webster DE, Khavari PA, Chang HY. Dicer-microRNA-Myc circuit promotes transcription of hundreds of long noncoding RNAs. Nature Structural & Molecular Biology. 21: 585-90. PMID 24929436 DOI: 10.1038/nsmb.2842  1
2014 Flynn RA, Chang HY. Long noncoding RNAs in cell-fate programming and reprogramming. Cell Stem Cell. 14: 752-61. PMID 24905165 DOI: 10.1016/j.stem.2014.05.014  1
2014 Buenrostro JD, Araya CL, Chircus LM, Layton CJ, Chang HY, Snyder MP, Greenleaf WJ. Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes. Nature Biotechnology. 32: 562-8. PMID 24727714 DOI: 10.1038/nbt.2880  1
2014 Yang YW, Flynn RA, Chen Y, Qu K, Wan B, Wang KC, Lei M, Chang HY. Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency. Elife. 3: e02046. PMID 24521543 DOI: 10.7554/eLife.02046  1
2014 Wan Y, Qu K, Zhang QC, Flynn RA, Manor O, Ouyang Z, Zhang J, Spitale RC, Snyder MP, Segal E, Chang HY. Landscape and variation of RNA secondary structure across the human transcriptome. Nature. 505: 706-9. PMID 24476892 DOI: 10.1038/nature12946  1
2014 Chang AL, Atzmon G, Bergman A, Brugmann S, Atwood SX, Chang HY, Barzilai N. Identification of genes promoting skin youthfulness by genome-wide association study. The Journal of Investigative Dermatology. 134: 651-7. PMID 24037343 DOI: 10.1038/jid.2013.381  1
2013 Harcourt EM, Ehrenschwender T, Batista PJ, Chang HY, Kool ET. Identification of a selective polymerase enables detection of N(6)-methyladenosine in RNA. Journal of the American Chemical Society. 135: 19079-82. PMID 24328136 DOI: 10.1021/ja4105792  1
2013 Wapinski OL, Vierbuchen T, Qu K, Lee QY, Chanda S, Fuentes DR, Giresi PG, Ng YH, Marro S, Neff NF, Drechsel D, Martynoga B, Castro DS, Webb AE, Südhof TC, ... ... Chang HY, et al. Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Cell. 155: 621-35. PMID 24243019 DOI: 10.1016/j.cell.2013.09.028  0.36
2013 Whyte JL, Smith AA, Liu B, Manzano WR, Evans ND, Dhamdhere GR, Fang MY, Chang HY, Oro AE, Helms JA. Augmenting endogenous Wnt signaling improves skin wound healing. Plos One. 8: e76883. PMID 24204695 DOI: 10.1371/journal.pone.0076883  1
2013 Buenrostro JD, Giresi PG, Zaba LC, Chang HY, Greenleaf WJ. Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. Nature Methods. 10: 1213-8. PMID 24097267 DOI: 10.1038/nmeth.2688  1
2013 Li L, Liu B, Wapinski OL, Tsai MC, Qu K, Zhang J, Carlson JC, Lin M, Fang F, Gupta RA, Helms JA, Chang HY. Targeted disruption of Hotair leads to homeotic transformation and gene derepression. Cell Reports. 5: 3-12. PMID 24075995 DOI: 10.1016/j.celrep.2013.09.003  1
2013 Schmitt AM, Chang HY. Gene regulation: Long RNAs wire up cancer growth. Nature. 500: 536-7. PMID 23945584 DOI: 10.1038/nature12548  1
2013 Rapicavoli NA, Qu K, Zhang J, Mikhail M, Laberge RM, Chang HY. A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics. Elife. 2: e00762. PMID 23898399 DOI: 10.7554/eLife.00762  1
2013 Ilik IA, Quinn JJ, Georgiev P, Tavares-Cadete F, Maticzka D, Toscano S, Wan Y, Spitale RC, Luscombe N, Backofen R, Chang HY, Akhtar A. Tandem stem-loops in roX RNAs act together to mediate X chromosome dosage compensation in Drosophila. Molecular Cell. 51: 156-73. PMID 23870142 DOI: 10.1016/j.molcel.2013.07.001  0.44
2013 Shah N, Jin K, Cruz LA, Park S, Sadik H, Cho S, Goswami CP, Nakshatri H, Gupta R, Chang HY, Zhang Z, Cimino-Mathews A, Cope L, Umbricht C, Sukumar S. HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression. Cancer Research. 73: 5449-58. PMID 23832664 DOI: 10.1158/0008-5472.CAN-13-1178  1
2013 Wan Y, Qu K, Ouyang Z, Chang HY. Genome-wide mapping of RNA structure using nuclease digestion and high-throughput sequencing. Nature Protocols. 8: 849-69. PMID 23558785 DOI: 10.1038/nprot.2013.045  1
2013 Batista PJ, Chang HY. Long noncoding RNAs: cellular address codes in development and disease. Cell. 152: 1298-307. PMID 23498938 DOI: 10.1016/j.cell.2013.02.012  1
2013 Gomez JA, Wapinski OL, Yang YW, Bureau JF, Gopinath S, Monack DM, Chang HY, Brahic M, Kirkegaard K. The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus. Cell. 152: 743-54. PMID 23415224 DOI: 10.1016/j.cell.2013.01.015  1
2013 Batista PJ, Chang HY. Cytotopic localization by long noncoding RNAs. Current Opinion in Cell Biology. 25: 195-9. PMID 23279909 DOI: 10.1016/j.ceb.2012.12.001  1
2013 Kretz M, Siprashvili Z, Chu C, Webster DE, Zehnder A, Qu K, Lee CS, Flockhart RJ, Groff AF, Chow J, Johnston D, Kim GE, Spitale RC, Flynn RA, Zheng GX, ... ... Chang HY, et al. Control of somatic tissue differentiation by the long non-coding RNA TINCR. Nature. 493: 231-5. PMID 23201690 DOI: 10.1038/nature11661  1
2013 Spitale RC, Crisalli P, Flynn RA, Torre EA, Kool ET, Chang HY. RNA SHAPE analysis in living cells. Nature Chemical Biology. 9: 18-20. PMID 23178934 DOI: 10.1038/nchembio.1131  1
2013 Ouyang Z, Snyder MP, Chang HY. SeqFold: genome-scale reconstruction of RNA secondary structure integrating high-throughput sequencing data. Genome Research. 23: 377-87. PMID 23064747 DOI: 10.1101/gr.138545.112  1
2013 Chang AL, Bitter PH, Qu K, Lin M, Rapicavoli NA, Chang HY. Rejuvenation of gene expression pattern of aged human skin by broadband light treatment: a pilot study. The Journal of Investigative Dermatology. 133: 394-402. PMID 22931923 DOI: 10.1038/jid.2012.287  1
2013 Chang HY, Thomson JA, Chen X. Microarray Analysis of Stem Cells and Differentiation Handbook of Stem Cells. 1: 399-407. DOI: 10.1016/B978-0-12-385942-6.00034-2  1
2012 Siprashvili Z, Webster DE, Kretz M, Johnston D, Rinn JL, Chang HY, Khavari PA. Identification of proteins binding coding and non-coding human RNAs using protein microarrays. Bmc Genomics. 13: 633. PMID 23157412 DOI: 10.1186/1471-2164-13-633  1
2012 Martin L, Meier M, Lyons SM, Sit RV, Marzluff WF, Quake SR, Chang HY. Systematic reconstruction of RNA functional motifs with high-throughput microfluidics Nature Methods. 9: 1192-1194. PMID 23142872 DOI: 10.1038/nmeth.2225  1
2012 Chisholm KM, Wan Y, Li R, Montgomery KD, Chang HY, West RB. Detection of long non-coding RNA in archival tissue: correlation with polycomb protein expression in primary and metastatic breast carcinoma. Plos One. 7: e47998. PMID 23133536 DOI: 10.1371/journal.pone.0047998  1
2012 Wan Y, Qu K, Ouyang Z, Kertesz M, Li J, Tibshirani R, Makino DL, Nutter RC, Segal E, Chang HY. Genome-wide measurement of RNA folding energies. Molecular Cell. 48: 169-81. PMID 22981864 DOI: 10.1016/j.molcel.2012.08.008  1
2012 Lee CS, Ungewickell A, Bhaduri A, Qu K, Webster DE, Armstrong R, Weng WK, Aros CJ, Mah A, Chen RO, Lin M, Sundram U, Chang HY, Kretz M, Kim YH, et al. Transcriptome sequencing in Sezary syndrome identifies Sezary cell and mycosis fungoides-associated lncRNAs and novel transcripts. Blood. 120: 3288-97. PMID 22936659 DOI: 10.1182/blood-2012-04-423061  1
2012 Brunner AL, Beck AH, Edris B, Sweeney RT, Zhu SX, Li R, Montgomery K, Varma S, Gilks T, Guo X, Foley JW, Witten DM, Giacomini CP, Flynn RA, Pollack JR, ... ... Chang HY, et al. Transcriptional profiling of long non-coding RNAs and novel transcribed regions across a diverse panel of archived human cancers. Genome Biology. 13: R75. PMID 22929540 DOI: 10.1186/gb-2012-13-8-r75  1
2012 Littlepage LE, Adler AS, Kouros-Mehr H, Huang G, Chou J, Krig SR, Griffith OL, Korkola JE, Qu K, Lawson DA, Xue Q, Sternlicht MD, Dijkgraaf GJ, Yaswen P, Rugo HS, ... ... Chang HY, et al. The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression. Cancer Discovery. 2: 638-51. PMID 22728437 DOI: 10.1158/2159-8290.CD-12-0093  1
2012 Rinn JL, Chang HY. Genome regulation by long noncoding RNAs. Annual Review of Biochemistry. 81: 145-66. PMID 22663078 DOI: 10.1146/annurev-biochem-051410-092902  1
2012 Wu AR, Kawahara TLA, Rapicavoli NA, Riggelen JV, Shroff EH, Xu L, Felsher DW, Chang HY, Quake SR. High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation Lab On a Chip - Miniaturisation For Chemistry and Biology. 12: 2190-2198. PMID 22566096 DOI: 10.1039/c2lc21290k  1
2012 Martin L, Chang HY. Uncovering the role of genomic "dark matter" in human disease. The Journal of Clinical Investigation. 122: 1589-95. PMID 22546862 DOI: 10.1172/JCI60020  1
2012 Chu C, Quinn J, Chang HY. Chromatin isolation by RNA purification (ChIRP). Journal of Visualized Experiments : Jove. PMID 22472705 DOI: 10.3791/3912  1
2012 Kretz M, Webster DE, Flockhart RJ, Lee CS, Zehnder A, Lopez-Pajares V, Qu K, Zheng GX, Chow J, Kim GE, Rinn JL, Chang HY, Siprashvili Z, Khavari PA. Suppression of progenitor differentiation requires the long noncoding RNA ANCR. Genes & Development. 26: 338-43. PMID 22302877 DOI: 10.1101/gad.182121.111  1
2012 Rando TA, Chang HY. Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock. Cell. 148: 46-57. PMID 22265401 DOI: 10.1016/j.cell.2012.01.003  1
2012 Wang P, McKnight KD, Wong DJ, Rodriguez RT, Sugiyama T, Gu X, Ghodasara A, Qu K, Chang HY, Kim SK. A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells. Stem Cells and Development. 21: 2273-87. PMID 22236333 DOI: 10.1089/scd.2011.0416  1
2012 Flynn RA, Chang HY. Active chromatin and noncoding RNAs: an intimate relationship. Current Opinion in Genetics & Development. 22: 172-8. PMID 22154525 DOI: 10.1016/j.gde.2011.11.002  1
2011 Chang H. Howard chang: Gene regulation in time and space Journal of Cell Biology. 195: 4-5. PMID 21969465 DOI: 10.1083/jcb.1951pi  1
2011 Chu C, Qu K, Zhong FL, Artandi SE, Chang HY. Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. Molecular Cell. 44: 667-78. PMID 21963238 DOI: 10.1016/j.molcel.2011.08.027  0.6
2011 Marro S, Pang ZP, Yang N, Tsai MC, Qu K, Chang HY, Südhof TC, Wernig M. Direct lineage conversion of terminally differentiated hepatocytes to functional neurons. Cell Stem Cell. 9: 374-82. PMID 21962918 DOI: 10.1016/j.stem.2011.09.002  0.6
2011 Wang KC, Chang HY. Molecular mechanisms of long noncoding RNAs. Molecular Cell. 43: 904-14. PMID 21925379 DOI: 10.1016/j.molcel.2011.08.018  1
2011 Wan Y, Kertesz M, Spitale RC, Segal E, Chang HY. Understanding the transcriptome through RNA structure. Nature Reviews. Genetics. 12: 641-55. PMID 21850044 DOI: 10.1038/nrg3049  1
2011 Alastalo TP, Li M, De Jesus Perez V, Pham D, Sawada H, Wang JK, Koskenvuo M, Wang L, Freeman BA, Chang HY, Rabinovitch M. Disruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival Journal of Clinical Investigation. 121: 3735-3746. PMID 21821917 DOI: 10.1172/JCI43382  1
2011 Kawahara TLA, Rapicavoli NA, Wu AR, Qu K, Quake SR, Chang HY. Dynamic chromatin localization of sirt6 shapes stress- and aging-related transcriptional networks Plos Genetics. 7. PMID 21738489 DOI: 10.1371/journal.pgen.1002153  1
2011 Chen Y, Wan B, Wang KC, Cao F, Yang Y, Protacio A, Dou Y, Chang HY, Lei M. Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding. Embo Reports. 12: 797-803. PMID 21660059 DOI: 10.1038/embor.2011.101  1
2011 Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, Horlings HM, Shah N, Umbricht C, Wang P, Wang Y, Kong B, Langerød A, Børresen-Dale AL, Kim SK, ... ... Chang HY, et al. Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. Nature Genetics. 43: 621-9. PMID 21642992 DOI: 10.1038/ng.848  1
2011 Wapinski O, Chang HY. Long noncoding RNAs and human disease. Trends in Cell Biology. 21: 354-61. PMID 21550244 DOI: 10.1016/j.tcb.2011.04.001  1
2011 Wang KC, Yang YW, Liu B, Sanyal A, Corces-Zimmerman R, Chen Y, Lajoie BR, Protacio A, Flynn RA, Gupta RA, Wysocka J, Lei M, Dekker J, Helms JA, Chang HY. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature. 472: 120-4. PMID 21423168 DOI: 10.1038/nature09819  1
2011 Spitale RC, Tsai MC, Chang HY. RNA templating the epigenome: long noncoding RNAs as molecular scaffolds. Epigenetics : Official Journal of the Dna Methylation Society. 6: 539-43. PMID 21393997 DOI: 10.4161/epi.6.5.15221  1
2011 Tsai MC, Spitale RC, Chang HY. Long intergenic noncoding RNAs: new links in cancer progression. Cancer Research. 71: 3-7. PMID 21199792 DOI: 10.1158/0008-5472.CAN-10-2483  1
2011 Wapinski O, Chang HY. Corrigendum: Long noncoding RNAs and human disease. [Trends in Cell Biology 21 (2011), 354-361] Trends in Cell Biology. 21: 561. DOI: 10.1016/j.tcb.2011.08.004  1
2010 Ouyang Z, Zheng GX, Chang HY. Noncoding RNA landmarks of pluripotency and reprogramming. Cell Stem Cell. 7: 649-50. PMID 21112559 DOI: 10.1016/j.stem.2010.11.018  1
2010 Wirt SE, Adler AS, Gebala V, Weimann JM, Schaffer BE, Saddic LA, Viatour P, Vogel H, Chang HY, Meissner A, Sage J. G1 arrest and differentiation can occur independently of Rb family function. The Journal of Cell Biology. 191: 809-25. PMID 21059851 DOI: 10.1083/jcb.201003048  1
2010 Hung T, Chang HY. Long noncoding RNA in genome regulation: prospects and mechanisms. Rna Biology. 7: 582-5. PMID 20930520  1
2010 Wan Y, Chang HY. HOTAIR: Flight of noncoding RNAs in cancer metastasis. Cell Cycle (Georgetown, Tex.). 9: 3391-2. PMID 20864820 DOI: 10.4161/cc.9.17.13122  1
2010 Kertesz M, Wan Y, Mazor E, Rinn JL, Nutter RC, Chang HY, Segal E. Genome-wide measurement of RNA secondary structure in yeast. Nature. 467: 103-7. PMID 20811459 DOI: 10.1038/nature09322  1
2010 Tsai MC, Manor O, Wan Y, Mosammaparast N, Wang JK, Lan F, Shi Y, Segal E, Chang HY. Long noncoding RNA as modular scaffold of histone modification complexes. Science (New York, N.Y.). 329: 689-93. PMID 20616235 DOI: 10.1126/science.1192002  1
2010 Tsai MC, Wang JK, Chang HY. Tumor suppression by the histone demethylase UTX. Cell Cycle (Georgetown, Tex.). 9: 2043-4. PMID 20505331 DOI: 10.4161/cc.9.11.11845  1
2010 Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, Wang Y, Brzoska P, Kong B, Li R, West RB, ... ... Chang HY, et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature. 464: 1071-6. PMID 20393566 DOI: 10.1038/nature08975  1
2010 Wang JK, Tsai MC, Poulin G, Adler AS, Chen S, Liu H, Shi Y, Chang HY. The histone demethylase UTX enables RB-dependent cell fate control. Genes & Development. 24: 327-32. PMID 20123895 DOI: 10.1101/gad.1882610  1
2010 Sargent JL, Milano A, Bhattacharyya S, Varga J, Connolly MK, Chang HY, Whitfield ML. A TGFbeta-responsive gene signature is associated with a subset of diffuse scleroderma with increased disease severity. The Journal of Investigative Dermatology. 130: 694-705. PMID 19812599 DOI: 10.1038/jid.2009.318  1
2009 Chang HY. Anatomic demarcation of cells: genes to patterns. Science (New York, N.Y.). 326: 1206-7. PMID 19965461 DOI: 10.1126/science.1175686  1
2009 Chan KS, Espinosa I, Chao M, Wong D, Ailles L, Diehn M, Gill H, Presti J, Chang HY, van de Rijn M, Shortliffe L, Weissman IL. Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 14016-21. PMID 19666525 DOI: 10.1073/pnas.0906549106  1
2009 Mace KA, Restivo TE, Rinn JL, Paquet AC, Chang HY, Young DM, Boudreau NJ. HOXA3 modulates injury-induced mobilization and recruitment of bone marrow-derived cells. Stem Cells (Dayton, Ohio). 27: 1654-65. PMID 19544454 DOI: 10.1002/stem.90  1
2009 Chang HY, Cuvier O, Dekker J. Gene dates, parties and galas. Symposium on Chromatin Dynamics and Higher Order Organization. Embo Reports. 10: 689-93. PMID 19525922 DOI: 10.1038/embor.2009.136  1
2009 Chan DA, Kawahara TL, Sutphin PD, Chang HY, Chi JT, Giaccia AJ. Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment. Cancer Cell. 15: 527-38. PMID 19477431 DOI: 10.1016/j.ccr.2009.04.010  1
2009 Reuter JA, Ortiz-Urda S, Kretz M, Garcia J, Scholl FA, Pasmooij AM, Cassarino D, Chang HY, Khavari PA. Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression. Cancer Cell. 15: 477-88. PMID 19477427 DOI: 10.1016/j.ccr.2009.04.002  1
2009 Wang KC, Helms JA, Chang HY. Regeneration, repair and remembering identity: the three Rs of Hox gene expression. Trends in Cell Biology. 19: 268-75. PMID 19428253 DOI: 10.1016/j.tcb.2009.03.007  1
2009 Rando OJ, Chang HY. Genome-wide views of chromatin structure. Annual Review of Biochemistry. 78: 245-71. PMID 19317649 DOI: 10.1146/annurev.biochem.78.071107.134639  1
2009 Somervaille TC, Matheny CJ, Spencer GJ, Iwasaki M, Rinn JL, Witten DM, Chang HY, Shurtleff SA, Downing JR, Cleary ML. Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells. Cell Stem Cell. 4: 129-40. PMID 19200802 DOI: 10.1016/j.stem.2008.11.015  1
2009 Chung L, Fiorentino DF, Benbarak MJ, Adler AS, Mariano MM, Paniagua RT, Milano A, Connolly MK, Ratiner BD, Wiskocil RL, Whitfield ML, Chang HY, Robinson WH. Molecular framework for response to imatinib mesylate in systemic sclerosis. Arthritis and Rheumatism. 60: 584-91. PMID 19180499 DOI: 10.1002/art.24221  1
2009 Kawahara TL, Michishita E, Adler AS, Damian M, Berber E, Lin M, McCord RA, Ongaigui KC, Boxer LD, Chang HY, Chua KF. SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span. Cell. 136: 62-74. PMID 19135889 DOI: 10.1016/j.cell.2008.10.052  1
2008 Sääf AM, Tengvall-Linder M, Chang HY, Adler AS, Wahlgren CF, Scheynius A, Nordenskjöld M, Bradley M. Global expression profiling in atopic eczema reveals reciprocal expression of inflammatory and lipid genes. Plos One. 3: e4017. PMID 19107207 DOI: 10.1371/journal.pone.0004017  1
2008 Wong DJ, Segal E, Chang HY. Stemness, cancer and cancer stem cells. Cell Cycle (Georgetown, Tex.). 7: 3622-4. PMID 19029796  1
2008 Nuyten DS, Hastie T, Chi JT, Chang HY, van de Vijver MJ. Combining biological gene expression signatures in predicting outcome in breast cancer: An alternative to supervised classification. European Journal of Cancer (Oxford, England : 1990). 44: 2319-29. PMID 18715778 DOI: 10.1016/j.ejca.2008.07.015  1
2008 Gardner JM, Devoss JJ, Friedman RS, Wong DJ, Tan YX, Zhou X, Johannes KP, Su MA, Chang HY, Krummel MF, Anderson MS. Deletional tolerance mediated by extrathymic Aire-expressing cells. Science (New York, N.Y.). 321: 843-7. PMID 18687966 DOI: 10.1126/science.1159407  1
2008 Sen GL, Webster DE, Barragan DI, Chang HY, Khavari PA. Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Genes & Development. 22: 1865-70. PMID 18628393 DOI: 10.1101/gad.1673508  1
2008 Su MA, Giang K, Zumer K, Jiang H, Oven I, Rinn JL, Devoss JJ, Johannes KP, Lu W, Gardner J, Chang A, Bubulya P, Chang HY, Peterlin BM, Anderson MS. Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire. The Journal of Clinical Investigation. 118: 1712-26. PMID 18414681 DOI: 10.1172/JCI34523  1
2008 Wong DJ, Liu H, Ridky TW, Cassarino D, Segal E, Chang HY. Module map of stem cell genes guides creation of epithelial cancer stem cells. Cell Stem Cell. 2: 333-44. PMID 18397753 DOI: 10.1016/j.stem.2008.02.009  1
2008 Michishita E, McCord RA, Berber E, Kioi M, Padilla-Nash H, Damian M, Cheung P, Kusumoto R, Kawahara TL, Barrett JC, Chang HY, Bohr VA, Ried T, Gozani O, Chua KF. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature. 452: 492-6. PMID 18337721 DOI: 10.1038/nature06736  1
2008 Rinn JL, Wang JK, Liu H, Montgomery K, van de Rijn M, Chang HY. A systems biology approach to anatomic diversity of skin. The Journal of Investigative Dermatology. 128: 776-82. PMID 18337710 DOI: 10.1038/sj.jid.5700986  1
2008 Adler AS, Kawahara TL, Segal E, Chang HY. Reversal of aging by NFkappaB blockade. Cell Cycle (Georgetown, Tex.). 7: 556-9. PMID 18256548  1
2008 Sinha S, Adler AS, Field Y, Chang HY, Segal E. Systematic functional characterization of cis-regulatory motifs in human core promoters. Genome Research. 18: 477-88. PMID 18256240 DOI: 10.1101/gr.6828808  1
2008 Rinn JL, Wang JK, Allen N, Brugmann SA, Mikels AJ, Liu H, Ridky TW, Stadler HS, Nusse R, Helms JA, Chang HY. A dermal HOX transcriptional program regulates site-specific epidermal fate. Genes & Development. 22: 303-7. PMID 18245445 DOI: 10.1101/gad.1610508  1
2008 Adler AS, Littlepage LE, Lin M, Kawahara TL, Wong DJ, Werb Z, Chang HY. CSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progression. Cancer Research. 68: 506-15. PMID 18199546 DOI: 10.1158/0008-5472.CAN-07-3060  1
2008 Wong DJ, Nuyten DS, Regev A, Lin M, Adler AS, Segal E, van de Vijver MJ, Chang HY. Revealing targeted therapy for human cancer by gene module maps. Cancer Research. 68: 369-78. PMID 18199530 DOI: 10.1158/0008-5472.CAN-07-0382  1
2007 Adler AS, Sinha S, Kawahara TL, Zhang JY, Segal E, Chang HY. Motif module map reveals enforcement of aging by continual NF-kappaB activity. Genes & Development. 21: 3244-57. PMID 18055696 DOI: 10.1101/gad.1588507  1
2007 Lan F, Bayliss PE, Rinn JL, Whetstine JR, Wang JK, Chen S, Iwase S, Alpatov R, Issaeva I, Canaani E, Roberts TM, Chang HY, Shi Y. A histone H3 lysine 27 demethylase regulates animal posterior development. Nature. 449: 689-94. PMID 17851529 DOI: 10.1038/nature06192  1
2007 Rinn JL, Kertesz M, Wang JK, Squazzo SL, Xu X, Brugmann SA, Goodnough LH, Helms JA, Farnham PJ, Segal E, Chang HY. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell. 129: 1311-23. PMID 17604720 DOI: 10.1016/j.cell.2007.05.022  1
2007 Liu H, Adler AS, Segal E, Chang HY. A transcriptional program mediating entry into cellular quiescence. Plos Genetics. 3: e91. PMID 17559306 DOI: 10.1371/journal.pgen.0030091  1
2007 O'Geen H, Squazzo SL, Iyengar S, Blahnik K, Rinn JL, Chang HY, Green R, Farnham PJ. Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs. Plos Genetics. 3: e89. PMID 17542650 DOI: 10.1371/journal.pgen.0030089  1
2007 Segal E, Sirlin CB, Ooi C, Adler AS, Gollub J, Chen X, Chan BK, Matcuk GR, Barry CT, Chang HY, Kuo MD. Decoding global gene expression programs in liver cancer by noninvasive imaging. Nature Biotechnology. 25: 675-80. PMID 17515910 DOI: 10.1038/nbt1306  1
2006 Chang HY, Thomson JA, Chen X. Microarray analysis of stem cells and differentiation. Methods in Enzymology. 420: 225-54. PMID 17161699 DOI: 10.1016/S0076-6879(06)20010-7  1
2006 Nuyten DS, Kreike B, Hart AA, Chi JT, Sneddon JB, Wessels LF, Peterse HJ, Bartelink H, Brown PO, Chang HY, van de Vijver MJ. Predicting a local recurrence after breast-conserving therapy by gene expression profiling. Breast Cancer Research : Bcr. 8: R62. PMID 17069664 DOI: 10.1186/bcr1614  1
2006 Sneddon JB, Zhen HH, Montgomery K, van de Rijn M, Tward AD, West R, Gladstone H, Chang HY, Morganroth GS, Oro AE, Brown PO. Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 103: 14842-7. PMID 17003113 DOI: 10.1073/pnas.0606857103  1
2006 Rinn JL, Bondre C, Gladstone HB, Brown PO, Chang HY. Anatomic demarcation by positional variation in fibroblast gene expression programs. Plos Genetics. 2: e119. PMID 16895450 DOI: 10.1371/journal.pgen.0020119  1
2006 Ray S, Atkuri KR, Deb-Basu D, Adler AS, Chang HY, Herzenberg LA, Felsher DW. MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species. Cancer Research. 66: 6598-605. PMID 16818632 DOI: 10.1158/0008-5472.CAN-05-3115  1
2006 Adler AS, Chang HY. From description to causality: mechanisms of gene expression signatures in cancer. Cell Cycle (Georgetown, Tex.). 5: 1148-51. PMID 16721055  1
2006 Adler AS, Lin M, Horlings H, Nuyten DS, van de Vijver MJ, Chang HY. Genetic regulators of large-scale transcriptional signatures in cancer. Nature Genetics. 38: 421-30. PMID 16518402 DOI: 10.1038/ng1752  1
2005 Tang J, Chang HY, Yang X. The death domain-associated protein modulates activity of the transcription co-factor Skip/NcoA62. Febs Letters. 579: 2883-90. PMID 15878163 DOI: 10.1016/j.febslet.2005.04.029  0.72
2005 Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sørlie T, Dai H, He YD, van't Veer LJ, Bartelink H, van de Rijn M, Brown PO, van de Vijver MJ. Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proceedings of the National Academy of Sciences of the United States of America. 102: 3738-43. PMID 15701700 DOI: 10.1073/pnas.0409462102  1
2004 Chang HY, Sneddon JB, Alizadeh AA, Sood R, West RB, Montgomery K, Chi JT, van de Rijn M, Botstein D, Brown PO. Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. Plos Biology. 2: E7. PMID 14737219 DOI: 10.1371/journal.pbio.0020007  1
2003 Chi JT, Chang HY, Haraldsen G, Jahnsen FL, Troyanskaya OG, Chang DS, Wang Z, Rockson SG, van de Rijn M, Botstein D, Brown PO. Endothelial cell diversity revealed by global expression profiling. Proceedings of the National Academy of Sciences of the United States of America. 100: 10623-8. PMID 12963823 DOI: 10.1073/pnas.1434429100  1
2003 Chi JT, Chang HY, Wang NN, Chang DS, Dunphy N, Brown PO. Genomewide view of gene silencing by small interfering RNAs. Proceedings of the National Academy of Sciences of the United States of America. 100: 6343-6. PMID 12730368 DOI: 10.1073/pnas.1037853100  1
2002 Chang HY, Chi JT, Dudoit S, Bondre C, van de Rijn M, Botstein D, Brown PO. Diversity, topographic differentiation, and positional memory in human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 99: 12877-82. PMID 12297622 DOI: 10.1073/pnas.162488599  1
1999 Chang HY, Yang X, Baltimore D. Dissecting Fas signaling with an altered-specificity death-domain mutant: requirement of FADD binding for apoptosis but not Jun N-terminal kinase activation. Proceedings of the National Academy of Sciences of the United States of America. 96: 1252-6. PMID 9990010 DOI: 10.1073/pnas.96.4.1252  0.72
1998 Chang HY, Nishitoh H, Yang X, Ichijo H, Baltimore D. Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. Science (New York, N.Y.). 281: 1860-3. PMID 9743501 DOI: 10.1126/science.281.5384.1860  0.72
1998 Yang X, Chang HY, Baltimore D. Essential role of CED-4 oligomerization in CED-3 activation and apoptosis. Science (New York, N.Y.). 281: 1355-7. PMID 9721101  0.72
1998 Yang X, Chang HY, Baltimore D. Autoproteolytic activation of pro-caspases by oligomerization. Molecular Cell. 1: 319-25. PMID 9659928  0.72
1997 Yang X, Khosravi-Far R, Chang HY, Baltimore D. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell. 89: 1067-76. PMID 9215629  0.72
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