Howard Y. Chang - Publications

2014- Dermatology Stanford University, Palo Alto, CA 

241 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wu KE, Yost KE, Chang HY, Zou J. BABEL enables cross-modality translation between multiomic profiles at single-cell resolution. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33827925 DOI: 10.1073/pnas.2023070118  0.56
2020 Lu Z, Guo JK, Wei Y, Dou DR, Zarnegar B, Ma Q, Li R, Zhao Y, Liu F, Choudhry H, Khavari PA, Chang HY. Structural modularity of the XIST ribonucleoprotein complex. Nature Communications. 11: 6163. PMID 33268787 DOI: 10.1038/s41467-020-20040-3  1
2020 Corley M, Flynn RA, Lee B, Blue SM, Chang HY, Yeo GW. Footprinting SHAPE-eCLIP Reveals Transcriptome-wide Hydrogen Bonds at RNA-Protein Interfaces. Molecular Cell. PMID 33242392 DOI: 10.1016/j.molcel.2020.11.014  0.56
2020 Leavitt T, Hu MS, Borrelli MR, Januszyk M, Garcia JT, Ransom RC, Mascharak S, desJardins-Park HE, Litzenburger UM, Walmsley GG, Marshall CD, Moore AL, Duoto B, Adem S, Foster DS, ... ... Chang HY, et al. Prrx1 Fibroblasts Represent a Pro-fibrotic Lineage in the Mouse Ventral Dermis. Cell Reports. 33: 108356. PMID 33176144 DOI: 10.1016/j.celrep.2020.108356  0.4
2020 Wu KE, Fazal FM, Parker KR, Zou J, Chang HY. RNA-GPS Predicts SARS-CoV-2 RNA Residency to Host Mitochondria and Nucleolus. Cell Systems. PMID 32673562 DOI: 10.1016/J.Cels.2020.06.008  1
2020 Wu K, Zou J, Chang HY. RNA-GPS Predicts SARS-CoV-2 RNA Localization to Host Mitochondria and Nucleolus. Biorxiv : the Preprint Server For Biology. PMID 32511373 DOI: 10.1101/2020.04.28.065201  0.56
2020 Fazal FM, Chang HY. Subcellular Spatial Transcriptomes: Emerging Frontier for Understanding Gene Regulation. Cold Spring Harbor Symposia On Quantitative Biology. PMID 32482897 DOI: 10.1101/Sqb.2019.84.040352  1
2020 Wu KE, Parker KR, Fazal FM, Chang H, Zou J. RNA-GPS predicts high-resolution RNA subcellular localization and highlights the role of splicing. Rna (New York, N.Y.). PMID 32220894 DOI: 10.1261/Rna.074161.119  1
2020 Li Y, Gruber JJ, Litzenburger UM, Zhou Y, Miao YR, LaGory EL, Li AM, Hu Z, Yip M, Hart LS, Maris JM, Chang HY, Giaccia AJ, Ye J. Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia. Cell Death & Disease. 11: 102. PMID 32029721 DOI: 10.1038/S41419-020-2303-9  0.36
2020 Trevino AE, Sinnott-Armstrong N, Andersen J, Yoon SJ, Huber N, Pritchard JK, Chang HY, Greenleaf WJ, Pașca SP. Chromatin accessibility dynamics in a model of human forebrain development. Science (New York, N.Y.). 367. PMID 31974223 DOI: 10.1126/Science.Aay1645  0.36
2020 Chinta M, Foster D, Nguyen A, Salhotra A, Gulati G, Ransom RC, Jones RE, Titan AL, Marshall CD, Mascharak S, Hu M, Januszyk M, Gurtner GC, Wan DC, Norton JA, ... Chang HY, et al. Abstract 190: Dermal Wounding Reveals Focal Adhesion Kinase Dependent Tissue-Resident Fibroblast Progenitors Plastic and Reconstructive Surgery. Global Open. 8: 129-130. DOI: 10.1097/01.Gox.0000667816.27720.Fd  0.4
2019 Fang J, Ma Q, Chu C, Huang B, Li L, Cai P, Batista PJ, Tolentino KEM, Xu J, Li R, Du P, Qu K, Chang HY. PIRCh-seq: functional classification of non-coding RNAs associated with distinct histone modifications. Genome Biology. 20: 292. PMID 31862000 DOI: 10.1186/S13059-019-1880-3  1
2019 Esfahani MS, Lee LJ, Jeon YJ, Flynn RA, Stehr H, Hui AB, Ishisoko N, Kildebeck E, Newman AM, Bratman SV, Porteus MH, Chang HY, Alizadeh AA, Diehn M. Functional significance of U2AF1 S34F mutations in lung adenocarcinomas. Nature Communications. 10: 5712. PMID 31836708 DOI: 10.1038/S41467-019-13392-Y  0.56
2019 Fazal FM, Han S, Parker KR, Kaewsapsak P, Xu J, Boettiger AN, Chang HY, Ting AY. Atlas of Subcellular RNA Localization Revealed by APEX-Seq. Cell. PMID 31230715 DOI: 10.1016/J.Cell.2019.05.027  1
2019 Sun L, Fazal FM, Li P, Broughton JP, Lee B, Tang L, Huang W, Kool ET, Chang HY, Zhang QC. RNA structure maps across mammalian cellular compartments. Nature Structural & Molecular Biology. PMID 30886404 DOI: 10.1038/S41594-019-0200-7  1
2019 Li L, Wang Y, Torkelson JL, Shankar G, Pattison JM, Zhen HH, Fang F, Duren Z, Xin J, Gaddam S, Melo SP, Piekos SN, Li J, Liaw EJ, Chen L, ... ... Chang HY, et al. TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment. Cell Stem Cell. PMID 30686763 DOI: 10.1016/J.Stem.2018.12.012  0.68
2019 Luo C, Lee QY, Wapinski O, Castanon R, Nery JR, Mall M, Kareta MS, Cullen SM, Goodell MA, Chang HY, Wernig M, Ecker JR. Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons. Elife. 8. PMID 30644360 DOI: 10.7554/Elife.40197  0.36
2019 desJardins-Park HE, Moore AL, Litzenburger U, Mascharak S, Chinta M, Ransom RC, Hu MS, Lorenz HP, Chang HY, Longaker MT. Intrinsic Chromatin State and Extrinsic Wound-Related Cues Can Coordinate to Activate Fibroblasts for Scarring Journal of the American College of Surgeons. 229. DOI: 10.1016/J.Jamcollsurg.2019.08.491  0.4
2019 Simonetta F, Maas-Bauer K, Hirai T, Wenokur A, Fazal FM, Kambham N, Ribado J, Mavers M, Baker J, Bhatt AS, Chang HY, Negrin RS. Distinct Immune Regulatory Potential of Invariant Natural Killer T (iNKT) Cell Subsets: iNKT2 and iNKT17, but Not iNKT1, Protect from Graft-Versus-Host-Disease Biology of Blood and Marrow Transplantation. 25. DOI: 10.1016/J.Bbmt.2018.12.683  1
2018 Lu Z, Chang HY. The RNA Base-Pairing Problem and Base-Pairing Solutions. Cold Spring Harbor Perspectives in Biology. 10. PMID 30510063 DOI: 10.1101/Cshperspect.A034926  1
2018 Pattison JM, Melo SP, Piekos SN, Torkelson JL, Bashkirova E, Mumbach MR, Rajasingh C, Zhen HH, Li L, Liaw E, Alber D, Rubin AJ, Shankar G, Bao X, Chang HY, et al. Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment. Nature Genetics. PMID 30397335 DOI: 10.1038/S41588-018-0263-0  0.56
2018 Chu C, Chang HY. ChIRP-MS: RNA-Directed Proteomic Discovery. Methods in Molecular Biology (Clifton, N.J.). 1861: 37-45. PMID 30218357 DOI: 10.1007/978-1-4939-8766-5_3  0.6
2018 Arda HE, Tsai J, Rosli YR, Giresi P, Bottino R, Greenleaf WJ, Chang HY, Kim SK. A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas. Cell Systems. PMID 30145115 DOI: 10.1016/J.Cels.2018.07.007  0.36
2018 Gate RE, Cheng CS, Aiden AP, Siba A, Tabaka M, Lituiev D, Machol I, Gordon MG, Subramaniam M, Shamim M, Hougen KL, Wortman I, Huang SC, Durand NC, Feng T, ... ... Chang HY, et al. Genetic determinants of co-accessible chromatin regions in activated T cells across humans. Nature Genetics. PMID 29988122 DOI: 10.1038/S41588-018-0156-2  0.36
2018 Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo F, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, ... ... Chang HY, et al. Retraction Note: DDX5 and its associated lncRNA Rmrp modulate T17 cell effector functions. Nature. PMID 29973715 DOI: 10.1038/S41586-018-0311-Z  0.56
2018 Chen L, Roake CM, Freund A, Batista PJ, Tian S, Yin YA, Gajera CR, Lin S, Lee B, Pech MF, Venteicher AS, Das R, Chang HY, Artandi SE. An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1. Cell. PMID 29804836 DOI: 10.1016/J.Cell.2018.04.039  1
2018 Buenrostro JD, Corces MR, Lareau CA, Wu B, Schep AN, Aryee MJ, Majeti R, Chang HY, Greenleaf WJ. Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation. Cell. PMID 29706549 DOI: 10.1016/J.Cell.2018.03.074  0.36
2018 Calo E, Gu B, Bowen ME, Aryan F, Zalc A, Liang J, Flynn RA, Swigut T, Chang HY, Attardi LD, Wysocka J. Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders. Nature. PMID 29364875 DOI: 10.1038/Nature25449  0.56
2018 Koh AS, Miller EL, Buenrostro JD, Moskowitz DM, Wang J, Greenleaf WJ, Chang HY, Crabtree GR. Rapid chromatin repression by Aire provides precise control of immune tolerance. Nature Immunology. PMID 29335648 DOI: 10.1038/S41590-017-0032-8  0.36
2018 Luo C, Lee QY, Wapinski O, Castanon R, Nery JR, Mall M, Kareta MS, Cullen SM, Goodell MA, Chang HY, Wernig M, Ecker JR. Author response: Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons Elife. DOI: 10.7554/Elife.40197.020  0.36
2017 Corces MR, Chang HY, Majeti R. Preleukemic Hematopoietic Stem Cells in Human Acute Myeloid Leukemia. Frontiers in Oncology. 7: 263. PMID 29164062 DOI: 10.3389/Fonc.2017.00263  0.36
2017 Bailey AS, Batista PJ, Gold RS, Chen YG, de Rooij DG, Chang HY, Fuller MT. The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline. Elife. 6. PMID 29087293 DOI: 10.7554/Elife.26116  1
2017 Lu Z, Carter AC, Chang HY. Mechanistic insights in X-chromosome inactivation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28947655 DOI: 10.1098/Rstb.2016.0356  1
2017 Li HB, Tong J, Zhu S, Batista PJ, Duffy EE, Zhao J, Bailis W, Cao G, Kroehling L, Chen Y, Wang G, Broughton JP, Chen YG, Kluger Y, Simon MD, ... Chang HY, et al. m(6)A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways. Nature. PMID 28792938 DOI: 10.1038/Nature23450  1
2017 Chen YG, Kim MV, Chen X, Batista PJ, Aoyama S, Wilusz JE, Iwasaki A, Chang HY. Sensing Self and Foreign Circular RNAs by Intron Identity. Molecular Cell. PMID 28625551 DOI: 10.1016/J.Molcel.2017.05.022  1
2017 Simsek D, Tiu GC, Flynn RA, Byeon GW, Leppek K, Xu AF, Chang HY, Barna M. The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity. Cell. 169: 1051-1065.e18. PMID 28575669 DOI: 10.1016/J.Cell.2017.05.022  0.56
2017 Yang N, Chanda S, Marro S, Ng YH, Janas JA, Haag D, Ang CE, Tang Y, Flores Q, Mall M, Wapinski O, Li M, Ahlenius H, Rubenstein JL, Chang HY, et al. Generation of pure GABAergic neurons by transcription factor programming. Nature Methods. PMID 28504679 DOI: 10.1038/Nmeth.4291  0.36
2017 Chang J, Mancuso MR, Maier C, Liang X, Yuki K, Yang L, Kwong JW, Wang J, Rao V, Vallon M, Kosinski C, Zhang JJ, Mah AT, Xu L, Li L, ... ... Chang HY, et al. Gpr124 is essential for blood-brain barrier integrity in central nervous system disease. Nature Medicine. PMID 28288111 DOI: 10.1038/Nm.4309  0.6
2017 Schmitt AM, Chang HY. Long Noncoding RNAs: At the Intersection of Cancer and Chromatin Biology. Cold Spring Harbor Perspectives in Medicine. PMID 28193769 DOI: 10.1101/Cshperspect.A026492  0.72
2017 Litzenburger UM, Buenrostro JD, Wu B, Shen Y, Sheffield NC, Kathiria A, Greenleaf WJ, Chang HY. Single-cell epigenomic variability reveals functional cancer heterogeneity. Genome Biology. 18: 15. PMID 28118844 DOI: 10.1186/S13059-016-1133-7  0.36
2017 Bailey AS, Batista PJ, Gold RS, Chen YG, Rooij DGd, Chang HY, Fuller MT. Author response: The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline Elife. DOI: 10.7554/Elife.26116.050  1
2016 Liu SJ, Horlbeck MA, Cho SW, Birk HS, Malatesta M, He D, Attenello FJ, Villalta JE, Cho MY, Chen Y, Mandegar MA, Olvera MP, Gilbert LA, Conklin BR, Chang HY, et al. CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science (New York, N.Y.). PMID 27980086 DOI: 10.1126/Science.Aah7111  0.56
2016 Li L, Helms JA, Chang HY. Comment on "Hotair Is Dispensable for Mouse Development". Plos Genetics. 12: e1006406. PMID 27977686 DOI: 10.1371/Journal.Pgen.1006406  0.56
2016 Lee B, Flynn RA, Kadina A, Guo JK, Kool ET, Chang HY. Comparison of SHAPE Reagents for Mapping RNA Structures Inside Living Cells. Rna (New York, N.Y.). PMID 27879433 DOI: 10.1261/Rna.058784.116  0.56
2016 Fazal FM, Chang HY. lncRNA Structure: Message to the Heart. Molecular Cell. 64: 1-2. PMID 27716479 DOI: 10.1016/J.Molcel.2016.09.030  1
2016 Schmitt AM, Garcia JT, Hung T, Flynn RA, Shen Y, Qu K, Payumo AY, Peres-da-Silva A, Broz DK, Baum R, Guo S, Chen JK, Attardi LD, Chang HY. An inducible long noncoding RNA amplifies DNA damage signaling. Nature Genetics. PMID 27668660 DOI: 10.1038/Ng.3673  1
2016 Chu C, Chang HY. Understanding RNA-Chromatin Interactions Using Chromatin Isolation by RNA Purification (ChIRP). Methods in Molecular Biology (Clifton, N.J.). 1480: 115-23. PMID 27659979 DOI: 10.1007/978-1-4939-6380-5_10  0.6
2016 Mumbach MR, Rubin AJ, Flynn RA, Dai C, Khavari PA, Greenleaf WJ, Chang HY. HiChIP: efficient and sensitive analysis of protein-directed genome architecture. Nature Methods. PMID 27643841 DOI: 10.1038/Nmeth.3999  0.36
2016 Corces MR, Buenrostro JD, Wu B, Greenside PG, Chan SM, Koenig JL, Snyder MP, Pritchard JK, Kundaje A, Greenleaf WJ, Majeti R, Chang HY. Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution. Nature Genetics. PMID 27526324 DOI: 10.1038/Ng.3646  1
2016 Sadik H, Korangath P, Nguyen N, Győrffy B, Kumar R, Hedayati M, Teo WW, Park S, Panday H, Gonzalez Munoz T, Menyhart O, Shah N, Pandita RK, Chang JC, DeWeese TL, ... Chang HY, et al. HOXC10 expression supports the development of chemotherapy resistance by fine tuning DNA repair in breast cancer cells. Cancer Research. PMID 27302171 DOI: 10.1158/0008-5472.Can-16-0774  1
2016 Lu Z, Zhang QC, Lee B, Flynn RA, Smith MA, Robinson JT, Davidovich C, Gooding AR, Goodrich KJ, Mattick JS, Mesirov JP, Cech TR, Chang HY. RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure. Cell. PMID 27180905 DOI: 10.1016/J.Cell.2016.04.028  1
2016 Arda HE, Li L, Tsai J, Torre EA, Rosli Y, Peiris H, Spitale RC, Dai C, Gu X, Qu K, Wang P, Wang J, Grompe M, Scharfmann R, Snyder MS, ... ... Chang HY, et al. Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function. Cell Metabolism. PMID 27133132 DOI: 10.1016/J.Cmet.2016.04.002  1
2016 Zarnegar BJ, Flynn RA, Shen Y, Do BT, Chang HY, Khavari PA. irCLIP platform for efficient characterization of protein-RNA interactions. Nature Methods. PMID 27111506 DOI: 10.1038/Nmeth.3840  0.36
2016 Ma Q, Chang HY. Single-cell profiling of lncRNAs in the developing human brain. Genome Biology. 17: 68. PMID 27079200 DOI: 10.1186/S13059-016-0933-0  1
2016 Schmitt AM, Chang HY. Long Noncoding RNAs in Cancer Pathways. Cancer Cell. 29: 452-63. PMID 27070700 DOI: 10.1016/J.Ccell.2016.03.010  1
2016 Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, ... ... Chang HY, et al. Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. Molecular Cell. 62: 34-46. PMID 27058786 DOI: 10.1016/J.Molcel.2016.03.013  1
2016 Oh S, Flynn RA, Floor SN, Purzner J, Martin L, Do BT, Schubert S, Vaka D, Morrissy S, Li Y, Kool M, Hovestadt V, Jones DT, Northcott PA, Risch T, ... ... Chang HY, et al. Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress. Oncotarget. 7: 28169-82. PMID 27058758 DOI: 10.18632/Oncotarget.8612  1
2016 Lu Z, Chang HY. Decoding the RNA structurome. Current Opinion in Structural Biology. 36: 142-148. PMID 26923056 DOI: 10.1016/J.Sbi.2016.01.007  1
2016 He C, Hu H, Wilson KD, Wu H, Feng J, Xia S, Churko J, Qu K, Chang HY, Wu JC. Systematic Characterization of Long Non-Coding RNAs Reveals the Contrasting Coordination of Cis- and Trans- Molecular Regulation in Human Fetal and Adult Heart. Circulation. Cardiovascular Genetics. PMID 26896382 DOI: 10.1161/Circgenetics.115.001264  1
2016 Flynn RA, Do BT, Rubin AJ, Calo E, Lee B, Kuchelmeister H, Rale M, Chu C, Kool ET, Wysocka J, Khavari PA, Chang HY. 7SK-BAF axis controls pervasive transcription at enhancers. Nature Structural & Molecular Biology. PMID 26878240 DOI: 10.1038/Nsmb.3176  0.6
2016 Lee Y, Shin JH, Longmire M, Wang H, Kohrt HE, Chang HY, Sunwoo JB. CD44+ cells in head and neck squamous cell carcinoma suppress T cell-mediated immunity by selective constitutive and inducible expression of PD-L1. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26864211 DOI: 10.1158/1078-0432.Ccr-15-2665  0.4
2016 Lin WC, Chang HY, Chen JY. Electrotransfer of the tilapia piscidin 3 and tilapia piscidin 4 genes into skeletal muscle enhances the antibacterial and immunomodulatory functions of Oreochromis niloticus. Fish & Shellfish Immunology. PMID 26828260 DOI: 10.1016/j.fsi.2016.01.034  0.6
2016 Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo F, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, ... ... Chang HY, et al. Corrigendum: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions. Nature. PMID 26789242 DOI: 10.1038/Nature16968  0.56
2016 Chang HY, Chen CT, Lih TM, Lynn KS, Juo CG, Hsu WL, Sung TY. iMet-Q: A User-Friendly Tool for Label-Free Metabolomics Quantitation Using Dynamic Peak-Width Determination. Plos One. 11: e0146112. PMID 26784691 DOI: 10.1371/Journal.Pone.0146112  0.36
2016 Quinn JJ, Zhang QC, Georgiev P, Ilik IA, Akhtar A, Chang HY. Rapid evolutionary turnover underlies conserved lncRNA-genome interactions. Genes & Development. 30: 191-207. PMID 26773003 DOI: 10.1101/Gad.272187.115  1
2016 Flynn RA, Zhang QC, Spitale RC, Lee B, Mumbach MR, Chang HY. Transcriptome-wide interrogation of RNA secondary structure in living cells with icSHAPE. Nature Protocols. 11: 273-90. PMID 26766114 DOI: 10.1038/Nprot.2016.011  1
2016 Hsiao PJ, Chen GH, Chang YH, Chang CH, Chang H, Bai LY. An unresectable retroperitoneal malignant fibrous histiocytoma: A case report Oncology Letters. 11: 2403-2407. DOI: 10.3892/ol.2016.4283  0.36
2016 Chen CW, Chang HY, Chen JH, Weng R. Elucidating the role of conformity in innovative smartphones International Journal of Mobile Communications. 14: 56-78. DOI: 10.1504/IJMC.2016.073367  0.4
2016 Mumbach M, Rubin A, Flynn R, Dai C, Khavari P, Greenleaf W, Chang H. HiChIP: Protein-centric chromatin conformation Protocol Exchange. DOI: 10.1038/Protex.2016.071  0.36
2016 Chang HY, Wang WK, Chen KN, Su JK, Hsin CY, Li J, Wang YK, Lin HD. Phylogeography and genetic structure of the endemic cyprinid fish Microphysogobio brevirostris in northern Taiwan Biochemical Systematics and Ecology. 65: 176-184. DOI: 10.1016/j.bse.2016.02.020  0.68
2015 Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo FW, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, ... ... Chang HY, et al. DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions. Nature. PMID 26675721 DOI: 10.1038/Nature16193  0.56
2015 Quinn JJ, Chang HY. Unique features of long non-coding RNA biogenesis and function. Nature Reviews. Genetics. 17: 47-62. PMID 26666209 DOI: 10.1038/Nrg.2015.10  1
2015 Carlson HL, Quinn JJ, Yang YW, Thornburg CK, Chang HY, Stadler HS. LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes. Plos Genetics. 11: e1005680. PMID 26633036 DOI: 10.1371/Journal.Pgen.1005680  0.56
2015 Mazumdar C, Shen Y, Xavy S, Zhao F, Reinisch A, Li R, Corces MR, Flynn RA, Buenrostro JD, Chan SM, Thomas D, Koenig JL, Hong WJ, Chang HY, Majeti R. Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation. Cell Stem Cell. PMID 26607380 DOI: 10.1016/J.Stem.2015.09.017  0.36
2015 Li CT, Chang HY, Li YY, Huang YJ, Tsai YL, Vittal R, Sheng YJ, Ho KC. Electro-catalytic Zinc Composites as the Efficient Counter Electrodes of Dye-Sensitized Solar Cells: A Study on the Electrochemical Performances and Density Functional Theory Calculations. Acs Applied Materials & Interfaces. PMID 26599619 DOI: 10.1021/acsami.5b07724  0.36
2015 Chang HY, Huang CW, Chen YF, Chen SY, Sheng YJ, Tsao HK. Assembly of Lock and Key Colloids Mediated by Polymeric Depletant. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 26566068 DOI: 10.1021/acs.langmuir.5b02527  0.68
2015 Kuo SF, Chao TC, Chang HY, Hsueh C, Lin CL, Chiang KC, Chuang WY, Chen YC, Lin JD. Prognosis of papillary thyroid cancers with positive serum thyroglobulin antibody after total thyroidectomy. Asian Journal of Surgery / Asian Surgical Association. PMID 26553529 DOI: 10.1016/j.asjsur.2015.08.002  0.36
2015 Choong WK, Chang HY, Chen CT, Tsai CF, Hsu WL, Chen YJ, Sung TY. Informatics view on the challenges of identifying missing proteins from shotgun proteomics. Journal of Proteome Research. PMID 26549055 DOI: 10.1021/Acs.Jproteome.5B00482  0.36
2015 Chou HC, Wang YM, Chang HY. Design intelligent wheelchair with ECG measurement and wireless transmission function. Technology and Health Care : Official Journal of the European Society For Engineering and Medicine. PMID 26444818 DOI: 10.3233/THC-151092  0.6
2015 Spitale RC, Flynn RA, Zhang QC, Crisalli P, Lee B, Jung JW, Kuchelmeister HY, Batista PJ, Torre EA, Kool ET, Chang HY. Erratum: Structural imprints in vivo decode RNA regulatory mechanisms. Nature. PMID 26416736 DOI: 10.1038/Nature15717  1
2015 Qu K, Zaba LC, Giresi PG, Li R, Longmire M, Kim YH, Greenleaf WJ, Chang HY. Individuality and variation of personal regulomes in primary human T cells. Cell Systems. 1: 51-61. PMID 26251845 DOI: 10.1016/J.Cels.2015.06.003  1
2015 Harris A, Chang HY, Wang L, Sylvia M, Neale D, Levine D, Bennett W. Emergency Room Utilization After Medically Complicated Pregnancies: A Medicaid Claims Analysis. Journal of Women's Health (2002). PMID 26226405 DOI: 10.1089/Jwh.2014.5125  0.4
2015 Liu Y, Tan C, Chou H, Nayak A, Wu D, Ghosh R, Chang HY, Hao Y, Wang X, Kim JS, Piner R, Ruoff RS, Akinwande D, Lai K. Thermal Oxidation of WSe2 Nanosheets Adhered on SiO2/Si Substrates. Nano Letters. PMID 26171759 DOI: 10.1021/Acs.Nanolett.5B02069  0.4
2015 Chang HY, Park SY, Kim JA, Kim YK, Lee HJ. Early radiographic diagnosis of peri-implantitis enhances the outcome of peri-implantitis treatment: a 5-year retrospective study after non-surgical treatment. Journal of Periodontal & Implant Science. 45: 82-93. PMID 26131368 DOI: 10.5051/jpis.2015.45.3.82  0.36
2015 Roost C, Lynch SR, Batista PJ, Qu K, Chang HY, Kool ET. Correction to "Structure and Thermodynamics of N(6)-Methyladenosine in RNA: A Spring-Loaded Base Modification". Journal of the American Chemical Society. PMID 26087989 DOI: 10.1021/Jacs.5B05858  1
2015 Buenrostro JD, Wu B, Litzenburger UM, Ruff D, Gonzales ML, Snyder MP, Chang HY, Greenleaf WJ. Single-cell chromatin accessibility reveals principles of regulatory variation. Nature. 523: 486-90. PMID 26083756 DOI: 10.1038/Nature14590  1
2015 Tsai CY, Wen SY, Shibu MA, Yang YC, Peng H, Wang B, Wei YM, Chang HY, Lee CY, Huang CY, Kuo WW. Diallyl trisulfide protects against high glucose-induced cardiac apoptosis by stimulating the production of cystathionine gamma-lyase-derived hydrogen sulfide. International Journal of Cardiology. 195: 300-10. PMID 26056963 DOI: 10.1016/J.Ijcard.2015.05.111  0.4
2015 Chen CL, Chen FF, Lin CH, Lou SZ, Chang HY, Yeung KT. Effect of Anterior Ankle-Foot Orthoses on Weight Shift in Persons With Stroke. Archives of Physical Medicine and Rehabilitation. PMID 25998222 DOI: 10.1016/j.apmr.2015.05.003  0.36
2015 Satpathy AT, Chang HY. Long noncoding RNA in hematopoiesis and immunity. Immunity. 42: 792-804. PMID 25992856 DOI: 10.1016/J.Immuni.2015.05.004  1
2015 Lin CH, Lin CT, Huang HT, Zeng WS, Chiang SC, Chang HY. 60-GHz optical/wireless MIMO system integrated with optical subcarrier multiplexing and 2x2 wireless communication. Optics Express. 23: 12111-6. PMID 25969299  0.6
2015 Wang RS, Chang HY, Kao SH, Kao CH, Wu YC, Yeh S, Tzeng CR, Chang C. Abnormal mitochondrial function and impaired granulosa cell differentiation in androgen receptor knockout mice. International Journal of Molecular Sciences. 16: 9831-49. PMID 25941928 DOI: 10.3390/ijms16059831  0.36
2015 Grow EJ, Flynn RA, Chavez SL, Bayless NL, Wossidlo M, Wesche DJ, Martin L, Ware CB, Blish CA, Chang HY, Pera RA, Wysocka J. Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells. Nature. 522: 221-5. PMID 25896322 DOI: 10.1038/Nature14308  1
2015 Hung CC, Chang HY, Luh DL, Wu CC, Yen LL. Do parents play different roles in drinking behaviours of male and female adolescents? A longitudinal follow-up study. Bmj Open. 5: e007179. PMID 25877273 DOI: 10.1136/bmjopen-2014-007179  0.4
2015 Chen LY, Wu PH, Guan HH, Fun HK, Chang HY, Chen CJ. Purification, crystallization and preliminary X-ray crystallographic analysis of the phosphatase domain (PA3346PD) of the response regulator PA3346 from Pseudomonas aeruginosa PAO1. Acta Crystallographica. Section F, Structural Biology Communications. 71: 434-7. PMID 25849505 DOI: 10.1107/S2053230X15004197  0.36
2015 Chu C, Zhang QC, da Rocha ST, Flynn RA, Bharadwaj M, Calabrese JM, Magnuson T, Heard E, Chang HY. Systematic discovery of Xist RNA binding proteins. Cell. 161: 404-16. PMID 25843628 DOI: 10.1016/J.Cell.2015.03.025  1
2015 Yu ST, Chang HY, Yao KP, Lin YH, Hurng BS. Validity of EQ-5D in general population of Taiwan: results of the 2009 National Health Interview and Drug Abuse Survey of Taiwan. Quality of Life Research : An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation. PMID 25833013 DOI: 10.1007/s11136-015-0978-7  0.4
2015 Chiou CJ, Wang HH, Chang HY. Development and testing of a scale for assessing the quality of home nursing. Geriatrics & Gerontology International. PMID 25809857 DOI: 10.1111/ggi.12478  0.4
2015 Spitale RC, Flynn RA, Zhang QC, Crisalli P, Lee B, Jung JW, Kuchelmeister HY, Batista PJ, Torre EA, Kool ET, Chang HY. Structural imprints in vivo decode RNA regulatory mechanisms. Nature. 519: 486-90. PMID 25799993 DOI: 10.1038/Nature14263  1
2015 Gilchrest BA, Campisi J, Chang HY, Fisher GJ, Kulesz-Martin MF. Montagna Symposium 2014-skin aging: molecular mechanisms and tissue consequences. The Journal of Investigative Dermatology. 135: 950-3. PMID 25785950 DOI: 10.1038/Jid.2014.546  1
2015 Zhao FR, Zhou DH, Lin T, Shao JJ, Wei P, Zhang YG, Chang HY. The first lack of evidence of H7N9 avian influenza virus infections among pigs in Eastern China. Microbial Pathogenesis. 80: 63-6. PMID 25680835 DOI: 10.1016/j.micpath.2015.02.003  0.6
2015 Chen CZ, Ou CY, Yu CH, Yang SC, Chang HY, Hsiue TR. Comparison of global initiative for chronic obstructive pulmonary disease 2013 classification and body mass index, airflow obstruction, dyspnea, and exacerbations index in predicting mortality and exacerbations in elderly adults with chronic obstructive pulmonary disease. Journal of the American Geriatrics Society. 63: 244-50. PMID 25641518 DOI: 10.1111/jgs.13258  0.56
2015 Cho SW, Chang HY. Genomics: CRISPR engineering turns on genes. Nature. 517: 560-2. PMID 25631441 DOI: 10.1038/517560A  1
2015 Corley M, Solem A, Qu K, Chang HY, Laederach A. Detecting riboSNitches with RNA folding algorithms: a genome-wide benchmark. Nucleic Acids Research. 43: 1859-68. PMID 25618847 DOI: 10.1093/Nar/Gkv010  1
2015 Roost C, Lynch SR, Batista PJ, Qu K, Chang HY, Kool ET. Structure and thermodynamics of N6-methyladenosine in RNA: a spring-loaded base modification. Journal of the American Chemical Society. 137: 2107-15. PMID 25611135 DOI: 10.1021/Ja513080V  1
2015 Chu C, Spitale RC, Chang HY. Technologies to probe functions and mechanisms of long noncoding RNAs. Nature Structural & Molecular Biology. 22: 29-35. PMID 25565030 DOI: 10.1038/Nsmb.2921  1
2015 Buenrostro JD, Wu B, Chang HY, Greenleaf WJ. ATAC-seq: A Method for Assaying Chromatin Accessibility Genome-Wide. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. 109: 21.29.1-9. PMID 25559105 DOI: 10.1002/0471142727.Mb2129S109  0.36
2015 Quinn JJ, Chang HY. In situ dissection of RNA functional subunits by domain-specific chromatin isolation by RNA purification (dChIRP). Methods in Molecular Biology (Clifton, N.J.). 1262: 199-213. PMID 25555583 DOI: 10.1007/978-1-4939-2253-6_12  1
2015 Lynn KS, Cheng ML, Chen YR, Hsu C, Chen A, Lih TM, Chang HY, Huang CJ, Shiao MS, Pan WH, Sung TY, Hsu WL. Metabolite identification for mass spectrometry-based metabolomics using multiple types of correlated ion information. Analytical Chemistry. 87: 2143-51. PMID 25543920 DOI: 10.1021/ac503325c  0.4
2015 Feng JY, Chang YT, Chang HY, Fetzer S, Wang JD. Prevalence of different forms of child maltreatment among Taiwanese adolescents: a population-based study. Child Abuse & Neglect. 42: 10-9. PMID 25477233 DOI: 10.1016/j.chiabu.2014.11.010  0.56
2015 Calo E, Flynn RA, Martin L, Spitale RC, Chang HY, Wysocka J. RNA helicase DDX21 coordinates transcription and ribosomal RNA processing. Nature. 518: 249-53. PMID 25470060 DOI: 10.1038/Nature13923  1
2015 Flynn RA, Martin L, Spitale RC, Do BT, Sagan SM, Zarnegar B, Qu K, Khavari PA, Quake SR, Sarnow P, Chang HY. Dissecting noncoding and pathogen RNA-protein interactomes. Rna (New York, N.Y.). 21: 135-43. PMID 25411354 DOI: 10.1261/Rna.047803.114  1
2015 Wang RS, Chang HY, Kao SH, Kao CH, Wu YC, Yeh S, Tzeng CR, Chang C. Abnormal mitochondrial function and impaired granulosa cell differentiation in androgen receptor knockout mice International Journal of Molecular Sciences. 16: 9831-9849. DOI: 10.3390/ijms16059831  0.36
2015 Kim DW, You SJ, Kim JH, Chang HY, Oh WY. Computational Characterization of a New Inductively Coupled Plasma Source for Application to Narrow Gap Plasma Processes Ieee Transactions On Plasma Science. DOI: 10.1109/TPS.2015.2475613  0.36
2015 Chang HY, Lin CH, Liu YC, Li WP, Wang YC. A 2.5 GHz High Efficiency High Power Low Phase Noise Monolithic Microwave Power Oscillator Ieee Microwave and Wireless Components Letters. DOI: 10.1109/LMWC.2015.2479849  0.6
2015 Kim DW, You SJ, Kim JH, Seong DJ, Chang HY, Oh WY. Computational study on reliability of sheath width measurement by the cutoff probe in low pressure plasmas Journal of Instrumentation. 10. DOI: 10.1088/1748-0221/10/11/T11001  0.36
2015 Chen SF, Chang HY, Wang SJ, Chen SH, Chen CC. Enhanced electromagnetic properties of Fe-Cr-Si alloy powders by sodium silicate treatment Journal of Alloys and Compounds. 637: 30-35. DOI: 10.1016/j.jallcom.2015.02.198  0.56
2014 Chang HY, Wahlqvist ML, Liu WL, Lee MS, Shin SJ, Li YS, Chang CJ, Chang CT, Fuh MT, Yang HJ, Tai TY, Hsu CC. Management trajectories in the type 2 diabetes Integrated Delivery System project in Taiwan: accounting for behavioral therapy, nutrition education and therapeutics. Asia Pacific Journal of Clinical Nutrition. 23: 592-606. PMID 25516317 DOI: 10.6133/apjcn.2014.23.4.06  0.4
2014 Chen CH, Wang PH, Hsieh MT, Tzeng CR, Wu YH, Lee CS, Chu YH, Chang HY. Sexual orientations of women with polycystic ovary syndrome: clinical observation in Taiwan. Taiwanese Journal of Obstetrics & Gynecology. 53: 542-6. PMID 25510698 DOI: 10.1016/j.tjog.2014.09.002  0.36
2014 Yeh YL, Chang HY. Design and analysis of a K-band low-phase-noise phase-locked loop with subharmonically injection-locked technique. Ieee Transactions On Ultrasonics, Ferroelectrics, and Frequency Control. 61: 1927-37. PMID 25474769 DOI: 10.1109/TUFFC.2012.005040  0.56
2014 Batista PJ, Molinie B, Wang J, Qu K, Zhang J, Li L, Bouley DM, Lujan E, Haddad B, Daneshvar K, Carter AC, Flynn RA, Zhou C, Lim KS, Dedon P, ... ... Chang HY, et al. m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells. Cell Stem Cell. 15: 707-19. PMID 25456834 DOI: 10.1016/J.Stem.2014.09.019  1
2014 Benitez CM, Qu K, Sugiyama T, Pauerstein PT, Liu Y, Tsai J, Gu X, Ghodasara A, Arda HE, Zhang J, Dekker JD, Tucker HO, Chang HY, Kim SK. An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development. Plos Genetics. 10: e1004645. PMID 25330008 DOI: 10.1371/Journal.Pgen.1004645  1
2014 Lee HJ, Kim HM, Kim N, Oh JC, Jo HJ, Lee JT, Chang HY, Chang NH, Ahn S, Lee JY. Association between halitosis diagnosed by a questionnaire and halimeter and symptoms of gastroesophageal reflux disease. Journal of Neurogastroenterology and Motility. 20: 483-90. PMID 25257469 DOI: 10.5056/jnm14052  0.36
2014 Yang SC, Lai WW, Chang HY, Su WC, Chen HH, Wang JD. Estimation of loss of quality-adjusted life expectancy (QALE) for patients with operable versus inoperable lung cancer: adjusting quality-of-life and lead-time bias for utility of surgery. Lung Cancer (Amsterdam, Netherlands). 86: 96-101. PMID 25178685 DOI: 10.1016/j.lungcan.2014.08.006  0.56
2014 Quinn JJ, Chang HY. RNA switch at enhancers. Nature Genetics. 46: 929-31. PMID 25162802 DOI: 10.1038/Ng.3074  1
2014 Spitale RC, Flynn RA, Torre EA, Kool ET, Chang HY. RNA structural analysis by evolving SHAPE chemistry. Wiley Interdisciplinary Reviews. Rna. 5: 867-81. PMID 25132067 DOI: 10.1002/Wrna.1253  1
2014 Chen CL, Teng YL, Lou SZ, Chang HY, Chen FF, Yeung KT. Effects of an anterior ankle-foot orthosis on walking mobility in stroke patients: get up and go and stair walking. Archives of Physical Medicine and Rehabilitation. 95: 2167-71. PMID 25128000 DOI: 10.1016/j.apmr.2014.07.408  0.36
2014 Li L, Chang HY. Physiological roles of long noncoding RNAs: insight from knockout mice. Trends in Cell Biology. 24: 594-602. PMID 25022466 DOI: 10.1016/J.Tcb.2014.06.003  1
2014 Quinn JJ, Ilik IA, Qu K, Georgiev P, Chu C, Akhtar A, Chang HY. Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification. Nature Biotechnology. 32: 933-40. PMID 24997788 DOI: 10.1038/Nbt.2943  1
2014 Zheng GX, Do BT, Webster DE, Khavari PA, Chang HY. Dicer-microRNA-Myc circuit promotes transcription of hundreds of long noncoding RNAs. Nature Structural & Molecular Biology. 21: 585-90. PMID 24929436 DOI: 10.1038/Nsmb.2842  1
2014 Flynn RA, Chang HY. Long noncoding RNAs in cell-fate programming and reprogramming. Cell Stem Cell. 14: 752-61. PMID 24905165 DOI: 10.1016/J.Stem.2014.05.014  1
2014 Buenrostro JD, Araya CL, Chircus LM, Layton CJ, Chang HY, Snyder MP, Greenleaf WJ. Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes. Nature Biotechnology. 32: 562-8. PMID 24727714 DOI: 10.1038/Nbt.2880  1
2014 Yang YW, Flynn RA, Chen Y, Qu K, Wan B, Wang KC, Lei M, Chang HY. Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency. Elife. 3: e02046. PMID 24521543 DOI: 10.7554/Elife.02046  1
2014 Wan Y, Qu K, Zhang QC, Flynn RA, Manor O, Ouyang Z, Zhang J, Spitale RC, Snyder MP, Segal E, Chang HY. Landscape and variation of RNA secondary structure across the human transcriptome. Nature. 505: 706-9. PMID 24476892 DOI: 10.1038/Nature12946  1
2014 Chang AL, Atzmon G, Bergman A, Brugmann S, Atwood SX, Chang HY, Barzilai N. Identification of genes promoting skin youthfulness by genome-wide association study. The Journal of Investigative Dermatology. 134: 651-7. PMID 24037343 DOI: 10.1038/Jid.2013.381  1
2013 Harcourt EM, Ehrenschwender T, Batista PJ, Chang HY, Kool ET. Identification of a selective polymerase enables detection of N(6)-methyladenosine in RNA. Journal of the American Chemical Society. 135: 19079-82. PMID 24328136 DOI: 10.1021/Ja4105792  1
2013 Wapinski OL, Vierbuchen T, Qu K, Lee QY, Chanda S, Fuentes DR, Giresi PG, Ng YH, Marro S, Neff NF, Drechsel D, Martynoga B, Castro DS, Webb AE, Südhof TC, ... ... Chang HY, et al. Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Cell. 155: 621-35. PMID 24243019 DOI: 10.1016/J.Cell.2013.09.028  0.6
2013 Whyte JL, Smith AA, Liu B, Manzano WR, Evans ND, Dhamdhere GR, Fang MY, Chang HY, Oro AE, Helms JA. Augmenting endogenous Wnt signaling improves skin wound healing. Plos One. 8: e76883. PMID 24204695 DOI: 10.1371/Journal.Pone.0076883  1
2013 Buenrostro JD, Giresi PG, Zaba LC, Chang HY, Greenleaf WJ. Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. Nature Methods. 10: 1213-8. PMID 24097267 DOI: 10.1038/Nmeth.2688  1
2013 Li L, Liu B, Wapinski OL, Tsai MC, Qu K, Zhang J, Carlson JC, Lin M, Fang F, Gupta RA, Helms JA, Chang HY. Targeted disruption of Hotair leads to homeotic transformation and gene derepression. Cell Reports. 5: 3-12. PMID 24075995 DOI: 10.1016/J.Celrep.2013.09.003  1
2013 Schmitt AM, Chang HY. Gene regulation: Long RNAs wire up cancer growth. Nature. 500: 536-7. PMID 23945584 DOI: 10.1038/Nature12548  1
2013 Rapicavoli NA, Qu K, Zhang J, Mikhail M, Laberge RM, Chang HY. A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics. Elife. 2: e00762. PMID 23898399 DOI: 10.7554/Elife.00762  1
2013 Ilik IA, Quinn JJ, Georgiev P, Tavares-Cadete F, Maticzka D, Toscano S, Wan Y, Spitale RC, Luscombe N, Backofen R, Chang HY, Akhtar A. Tandem stem-loops in roX RNAs act together to mediate X chromosome dosage compensation in Drosophila. Molecular Cell. 51: 156-73. PMID 23870142 DOI: 10.1016/J.Molcel.2013.07.001  1
2013 Shah N, Jin K, Cruz LA, Park S, Sadik H, Cho S, Goswami CP, Nakshatri H, Gupta R, Chang HY, Zhang Z, Cimino-Mathews A, Cope L, Umbricht C, Sukumar S. HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression. Cancer Research. 73: 5449-58. PMID 23832664 DOI: 10.1158/0008-5472.Can-13-1178  1
2013 Wan Y, Qu K, Ouyang Z, Chang HY. Genome-wide mapping of RNA structure using nuclease digestion and high-throughput sequencing. Nature Protocols. 8: 849-69. PMID 23558785 DOI: 10.1038/Nprot.2013.045  1
2013 Batista PJ, Chang HY. Long noncoding RNAs: cellular address codes in development and disease. Cell. 152: 1298-307. PMID 23498938 DOI: 10.1016/J.Cell.2013.02.012  1
2013 Gomez JA, Wapinski OL, Yang YW, Bureau JF, Gopinath S, Monack DM, Chang HY, Brahic M, Kirkegaard K. The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus. Cell. 152: 743-54. PMID 23415224 DOI: 10.1016/J.Cell.2013.01.015  1
2013 Batista PJ, Chang HY. Cytotopic localization by long noncoding RNAs. Current Opinion in Cell Biology. 25: 195-9. PMID 23279909 DOI: 10.1016/J.Ceb.2012.12.001  1
2013 Kretz M, Siprashvili Z, Chu C, Webster DE, Zehnder A, Qu K, Lee CS, Flockhart RJ, Groff AF, Chow J, Johnston D, Kim GE, Spitale RC, Flynn RA, Zheng GX, ... ... Chang HY, et al. Control of somatic tissue differentiation by the long non-coding RNA TINCR. Nature. 493: 231-5. PMID 23201690 DOI: 10.1038/Nature11661  1
2013 Spitale RC, Crisalli P, Flynn RA, Torre EA, Kool ET, Chang HY. RNA SHAPE analysis in living cells. Nature Chemical Biology. 9: 18-20. PMID 23178934 DOI: 10.1038/Nchembio.1131  1
2013 Ouyang Z, Snyder MP, Chang HY. SeqFold: genome-scale reconstruction of RNA secondary structure integrating high-throughput sequencing data. Genome Research. 23: 377-87. PMID 23064747 DOI: 10.1101/Gr.138545.112  1
2013 Chang AL, Bitter PH, Qu K, Lin M, Rapicavoli NA, Chang HY. Rejuvenation of gene expression pattern of aged human skin by broadband light treatment: a pilot study. The Journal of Investigative Dermatology. 133: 394-402. PMID 22931923 DOI: 10.1038/Jid.2012.287  1
2013 Chang HY, Thomson JA, Chen X. Microarray Analysis of Stem Cells and Differentiation Handbook of Stem Cells. 1: 399-407. DOI: 10.1016/B978-0-12-385942-6.00034-2  1
2012 Siprashvili Z, Webster DE, Kretz M, Johnston D, Rinn JL, Chang HY, Khavari PA. Identification of proteins binding coding and non-coding human RNAs using protein microarrays. Bmc Genomics. 13: 633. PMID 23157412 DOI: 10.1186/1471-2164-13-633  1
2012 Martin L, Meier M, Lyons SM, Sit RV, Marzluff WF, Quake SR, Chang HY. Systematic reconstruction of RNA functional motifs with high-throughput microfluidics Nature Methods. 9: 1192-1194. PMID 23142872 DOI: 10.1038/Nmeth.2225  1
2012 Chisholm KM, Wan Y, Li R, Montgomery KD, Chang HY, West RB. Detection of long non-coding RNA in archival tissue: correlation with polycomb protein expression in primary and metastatic breast carcinoma. Plos One. 7: e47998. PMID 23133536 DOI: 10.1371/Journal.Pone.0047998  1
2012 Wan Y, Qu K, Ouyang Z, Kertesz M, Li J, Tibshirani R, Makino DL, Nutter RC, Segal E, Chang HY. Genome-wide measurement of RNA folding energies. Molecular Cell. 48: 169-81. PMID 22981864 DOI: 10.1016/J.Molcel.2012.08.008  1
2012 Lee CS, Ungewickell A, Bhaduri A, Qu K, Webster DE, Armstrong R, Weng WK, Aros CJ, Mah A, Chen RO, Lin M, Sundram U, Chang HY, Kretz M, Kim YH, et al. Transcriptome sequencing in Sezary syndrome identifies Sezary cell and mycosis fungoides-associated lncRNAs and novel transcripts. Blood. 120: 3288-97. PMID 22936659 DOI: 10.1182/Blood-2012-04-423061  1
2012 Brunner AL, Beck AH, Edris B, Sweeney RT, Zhu SX, Li R, Montgomery K, Varma S, Gilks T, Guo X, Foley JW, Witten DM, Giacomini CP, Flynn RA, Pollack JR, ... ... Chang HY, et al. Transcriptional profiling of long non-coding RNAs and novel transcribed regions across a diverse panel of archived human cancers. Genome Biology. 13: R75. PMID 22929540 DOI: 10.1186/Gb-2012-13-8-R75  1
2012 Littlepage LE, Adler AS, Kouros-Mehr H, Huang G, Chou J, Krig SR, Griffith OL, Korkola JE, Qu K, Lawson DA, Xue Q, Sternlicht MD, Dijkgraaf GJ, Yaswen P, Rugo HS, ... ... Chang HY, et al. The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression. Cancer Discovery. 2: 638-51. PMID 22728437 DOI: 10.1158/2159-8290.Cd-12-0093  1
2012 Rinn JL, Chang HY. Genome regulation by long noncoding RNAs. Annual Review of Biochemistry. 81: 145-66. PMID 22663078 DOI: 10.1182/Blood.V122.21.Sci-29.Sci-29  1
2012 Wu AR, Kawahara TLA, Rapicavoli NA, Riggelen JV, Shroff EH, Xu L, Felsher DW, Chang HY, Quake SR. High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation Lab On a Chip - Miniaturisation For Chemistry and Biology. 12: 2190-2198. PMID 22566096 DOI: 10.1039/C2Lc21290K  1
2012 Martin L, Chang HY. Uncovering the role of genomic "dark matter" in human disease. The Journal of Clinical Investigation. 122: 1589-95. PMID 22546862 DOI: 10.1172/Jci60020  1
2012 Chu C, Quinn J, Chang HY. Chromatin isolation by RNA purification (ChIRP). Journal of Visualized Experiments : Jove. PMID 22472705 DOI: 10.3791/3912  1
2012 Kretz M, Webster DE, Flockhart RJ, Lee CS, Zehnder A, Lopez-Pajares V, Qu K, Zheng GX, Chow J, Kim GE, Rinn JL, Chang HY, Siprashvili Z, Khavari PA. Suppression of progenitor differentiation requires the long noncoding RNA ANCR. Genes & Development. 26: 338-43. PMID 22302877 DOI: 10.1101/Gad.182121.111  1
2012 Rando TA, Chang HY. Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock. Cell. 148: 46-57. PMID 22265401 DOI: 10.1016/J.Cell.2012.01.003  1
2012 Wang P, McKnight KD, Wong DJ, Rodriguez RT, Sugiyama T, Gu X, Ghodasara A, Qu K, Chang HY, Kim SK. A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells. Stem Cells and Development. 21: 2273-87. PMID 22236333 DOI: 10.1089/Scd.2011.0416  1
2012 Flynn RA, Chang HY. Active chromatin and noncoding RNAs: an intimate relationship. Current Opinion in Genetics & Development. 22: 172-8. PMID 22154525 DOI: 10.1016/J.Gde.2011.11.002  1
2012 Chow NH, Chang HY, Chen SH, Liu HS. 212 The Involvement of DNA Double-strand Break Repair in Receptor Tyrosine Kinase RON-mediated Cancer Cell Response to Hypoxia European Journal of Cancer. 48. DOI: 10.1016/S0959-8049(12)70907-3  0.56
2011 Chang H. Howard chang: Gene regulation in time and space Journal of Cell Biology. 195: 4-5. PMID 21969465 DOI: 10.1083/jcb.1951pi  1
2011 Chu C, Qu K, Zhong FL, Artandi SE, Chang HY. Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. Molecular Cell. 44: 667-78. PMID 21963238 DOI: 10.1016/J.Molcel.2011.08.027  0.6
2011 Marro S, Pang ZP, Yang N, Tsai MC, Qu K, Chang HY, Südhof TC, Wernig M. Direct lineage conversion of terminally differentiated hepatocytes to functional neurons. Cell Stem Cell. 9: 374-82. PMID 21962918 DOI: 10.1016/J.Stem.2011.09.002  0.6
2011 Wang KC, Chang HY. Molecular mechanisms of long noncoding RNAs. Molecular Cell. 43: 904-14. PMID 21925379 DOI: 10.1016/J.Molcel.2011.08.018  1
2011 Wan Y, Kertesz M, Spitale RC, Segal E, Chang HY. Understanding the transcriptome through RNA structure. Nature Reviews. Genetics. 12: 641-55. PMID 21850044 DOI: 10.1038/Nrg3049  1
2011 Alastalo TP, Li M, De Jesus Perez V, Pham D, Sawada H, Wang JK, Koskenvuo M, Wang L, Freeman BA, Chang HY, Rabinovitch M. Disruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival Journal of Clinical Investigation. 121: 3735-3746. PMID 21821917 DOI: 10.1172/Jci43382  1
2011 Kawahara TLA, Rapicavoli NA, Wu AR, Qu K, Quake SR, Chang HY. Dynamic chromatin localization of sirt6 shapes stress- and aging-related transcriptional networks Plos Genetics. 7. PMID 21738489 DOI: 10.1371/Journal.Pgen.1002153  1
2011 Chen Y, Wan B, Wang KC, Cao F, Yang Y, Protacio A, Dou Y, Chang HY, Lei M. Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding. Embo Reports. 12: 797-803. PMID 21660059 DOI: 10.1038/Embor.2011.101  1
2011 Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, Horlings HM, Shah N, Umbricht C, Wang P, Wang Y, Kong B, Langerød A, Børresen-Dale AL, Kim SK, ... ... Chang HY, et al. Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. Nature Genetics. 43: 621-9. PMID 21642992 DOI: 10.1038/Ng.848  1
2011 Wapinski O, Chang HY. Long noncoding RNAs and human disease. Trends in Cell Biology. 21: 354-61. PMID 21550244 DOI: 10.1016/J.Tcb.2011.04.001  1
2011 Wang KC, Yang YW, Liu B, Sanyal A, Corces-Zimmerman R, Chen Y, Lajoie BR, Protacio A, Flynn RA, Gupta RA, Wysocka J, Lei M, Dekker J, Helms JA, Chang HY. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature. 472: 120-4. PMID 21423168 DOI: 10.1038/Nature09819  1
2011 Spitale RC, Tsai MC, Chang HY. RNA templating the epigenome: long noncoding RNAs as molecular scaffolds. Epigenetics : Official Journal of the Dna Methylation Society. 6: 539-43. PMID 21393997 DOI: 10.4161/Epi.6.5.15221  1
2011 Tsai MC, Spitale RC, Chang HY. Long intergenic noncoding RNAs: new links in cancer progression. Cancer Research. 71: 3-7. PMID 21199792 DOI: 10.1158/0008-5472.Can-10-2483  1
2011 Wapinski O, Chang HY. Corrigendum: Long noncoding RNAs and human disease. [Trends in Cell Biology 21 (2011), 354-361] Trends in Cell Biology. 21: 561. DOI: 10.1016/J.Tcb.2011.08.004  1
2010 Ouyang Z, Zheng GX, Chang HY. Noncoding RNA landmarks of pluripotency and reprogramming. Cell Stem Cell. 7: 649-50. PMID 21112559 DOI: 10.1016/J.Stem.2010.11.018  1
2010 Wirt SE, Adler AS, Gebala V, Weimann JM, Schaffer BE, Saddic LA, Viatour P, Vogel H, Chang HY, Meissner A, Sage J. G1 arrest and differentiation can occur independently of Rb family function. The Journal of Cell Biology. 191: 809-25. PMID 21059851 DOI: 10.1083/Jcb.201003048  1
2010 Hung T, Chang HY. Long noncoding RNA in genome regulation: prospects and mechanisms. Rna Biology. 7: 582-5. PMID 20930520 DOI: 10.4161/Rna.7.5.13216  1
2010 Wan Y, Chang HY. HOTAIR: Flight of noncoding RNAs in cancer metastasis. Cell Cycle (Georgetown, Tex.). 9: 3391-2. PMID 20864820 DOI: 10.4161/Cc.9.17.13122  1
2010 Kertesz M, Wan Y, Mazor E, Rinn JL, Nutter RC, Chang HY, Segal E. Genome-wide measurement of RNA secondary structure in yeast. Nature. 467: 103-7. PMID 20811459 DOI: 10.1038/Nature09322  1
2010 Tsai MC, Manor O, Wan Y, Mosammaparast N, Wang JK, Lan F, Shi Y, Segal E, Chang HY. Long noncoding RNA as modular scaffold of histone modification complexes. Science (New York, N.Y.). 329: 689-93. PMID 20616235 DOI: 10.1126/Science.1192002  1
2010 Tsai MC, Wang JK, Chang HY. Tumor suppression by the histone demethylase UTX. Cell Cycle (Georgetown, Tex.). 9: 2043-4. PMID 20505331 DOI: 10.4161/Cc.9.11.11845  1
2010 Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, Wang Y, Brzoska P, Kong B, Li R, West RB, ... ... Chang HY, et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature. 464: 1071-6. PMID 20393566 DOI: 10.1038/Nature08975  1
2010 Wang JK, Tsai MC, Poulin G, Adler AS, Chen S, Liu H, Shi Y, Chang HY. The histone demethylase UTX enables RB-dependent cell fate control. Genes & Development. 24: 327-32. PMID 20123895 DOI: 10.1101/Gad.1882610  1
2010 Sargent JL, Milano A, Bhattacharyya S, Varga J, Connolly MK, Chang HY, Whitfield ML. A TGFbeta-responsive gene signature is associated with a subset of diffuse scleroderma with increased disease severity. The Journal of Investigative Dermatology. 130: 694-705. PMID 19812599 DOI: 10.1038/Jid.2009.318  1
2010 Sadik H, Shah N, Gupta R, Chang H, Sukumar S. Abstract P4-01-03: The Homeobox Protein H0XC10 Is Overexpressed in Breast Cancer and Confers Resistance to Chemotherapy Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P4-01-03  0.36
2010 Kertesz M, Wan Y, Mazor E, Rinn J, Nutter R, Chang H, Segal E. Probing RNA structure genome-wide using high throughput sequencing Nature Protocols. DOI: 10.1038/Nprot.2010.152  1
2009 Wong DJ, Chang HY. Skin tissue engineering Stembook. PMID 20614591 DOI: 10.3824/Stembook.1.44.1  0.36
2009 Chang HY. Anatomic demarcation of cells: genes to patterns. Science (New York, N.Y.). 326: 1206-7. PMID 19965461 DOI: 10.1126/Science.1175686  1
2009 Chan KS, Espinosa I, Chao M, Wong D, Ailles L, Diehn M, Gill H, Presti J, Chang HY, van de Rijn M, Shortliffe L, Weissman IL. Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 14016-21. PMID 19666525 DOI: 10.1073/Pnas.0906549106  1
2009 Mace KA, Restivo TE, Rinn JL, Paquet AC, Chang HY, Young DM, Boudreau NJ. HOXA3 modulates injury-induced mobilization and recruitment of bone marrow-derived cells. Stem Cells (Dayton, Ohio). 27: 1654-65. PMID 19544454 DOI: 10.1002/Stem.90  1
2009 Chang HY, Cuvier O, Dekker J. Gene dates, parties and galas. Symposium on Chromatin Dynamics and Higher Order Organization. Embo Reports. 10: 689-93. PMID 19525922 DOI: 10.1038/Embor.2009.136  1
2009 Chan DA, Kawahara TL, Sutphin PD, Chang HY, Chi JT, Giaccia AJ. Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment. Cancer Cell. 15: 527-38. PMID 19477431 DOI: 10.1016/J.Ccr.2009.04.010  1
2009 Reuter JA, Ortiz-Urda S, Kretz M, Garcia J, Scholl FA, Pasmooij AM, Cassarino D, Chang HY, Khavari PA. Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression. Cancer Cell. 15: 477-88. PMID 19477427 DOI: 10.1016/J.Ccr.2009.04.002  1
2009 Wang KC, Helms JA, Chang HY. Regeneration, repair and remembering identity: the three Rs of Hox gene expression. Trends in Cell Biology. 19: 268-75. PMID 19428253 DOI: 10.1016/J.Tcb.2009.03.007  1
2009 Rando OJ, Chang HY. Genome-wide views of chromatin structure. Annual Review of Biochemistry. 78: 245-71. PMID 19317649 DOI: 10.1146/Annurev.Biochem.78.071107.134639  1
2009 Somervaille TC, Matheny CJ, Spencer GJ, Iwasaki M, Rinn JL, Witten DM, Chang HY, Shurtleff SA, Downing JR, Cleary ML. Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells. Cell Stem Cell. 4: 129-40. PMID 19200802 DOI: 10.1016/J.Stem.2008.11.015  1
2009 Hung T, Binda O, Champagne KS, Kuo AJ, Johnson K, Chang HY, Simon MD, Kutateladze TG, Gozani O. ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation. Molecular Cell. 33: 248-56. PMID 19187765 DOI: 10.1016/J.Molcel.2008.12.016  0.36
2009 Chung L, Fiorentino DF, Benbarak MJ, Adler AS, Mariano MM, Paniagua RT, Milano A, Connolly MK, Ratiner BD, Wiskocil RL, Whitfield ML, Chang HY, Robinson WH. Molecular framework for response to imatinib mesylate in systemic sclerosis. Arthritis and Rheumatism. 60: 584-91. PMID 19180499 DOI: 10.1002/Art.24221  1
2009 Kawahara TL, Michishita E, Adler AS, Damian M, Berber E, Lin M, McCord RA, Ongaigui KC, Boxer LD, Chang HY, Chua KF. SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span. Cell. 136: 62-74. PMID 19135889 DOI: 10.1016/J.Cell.2008.10.052  1
2008 Sääf AM, Tengvall-Linder M, Chang HY, Adler AS, Wahlgren CF, Scheynius A, Nordenskjöld M, Bradley M. Global expression profiling in atopic eczema reveals reciprocal expression of inflammatory and lipid genes. Plos One. 3: e4017. PMID 19107207 DOI: 10.1371/Journal.Pone.0004017  1
2008 Wong DJ, Segal E, Chang HY. Stemness, cancer and cancer stem cells. Cell Cycle (Georgetown, Tex.). 7: 3622-4. PMID 19029796 DOI: 10.4161/Cc.7.23.7104  1
2008 Nuyten DS, Hastie T, Chi JT, Chang HY, van de Vijver MJ. Combining biological gene expression signatures in predicting outcome in breast cancer: An alternative to supervised classification. European Journal of Cancer (Oxford, England : 1990). 44: 2319-29. PMID 18715778 DOI: 10.1016/J.Ejca.2008.07.015  1
2008 Gardner JM, Devoss JJ, Friedman RS, Wong DJ, Tan YX, Zhou X, Johannes KP, Su MA, Chang HY, Krummel MF, Anderson MS. Deletional tolerance mediated by extrathymic Aire-expressing cells. Science (New York, N.Y.). 321: 843-7. PMID 18687966 DOI: 10.1126/Science.1159407  1
2008 Sen GL, Webster DE, Barragan DI, Chang HY, Khavari PA. Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Genes & Development. 22: 1865-70. PMID 18628393 DOI: 10.1101/Gad.1673508  1
2008 Su MA, Giang K, Zumer K, Jiang H, Oven I, Rinn JL, Devoss JJ, Johannes KP, Lu W, Gardner J, Chang A, Bubulya P, Chang HY, Peterlin BM, Anderson MS. Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire. The Journal of Clinical Investigation. 118: 1712-26. PMID 18414681 DOI: 10.1172/Jci34523  1
2008 Wong DJ, Liu H, Ridky TW, Cassarino D, Segal E, Chang HY. Module map of stem cell genes guides creation of epithelial cancer stem cells. Cell Stem Cell. 2: 333-44. PMID 18397753 DOI: 10.1016/J.Stem.2008.02.009  1
2008 Michishita E, McCord RA, Berber E, Kioi M, Padilla-Nash H, Damian M, Cheung P, Kusumoto R, Kawahara TL, Barrett JC, Chang HY, Bohr VA, Ried T, Gozani O, Chua KF. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature. 452: 492-6. PMID 18337721 DOI: 10.1038/Nature06736  1
2008 Rinn JL, Wang JK, Liu H, Montgomery K, van de Rijn M, Chang HY. A systems biology approach to anatomic diversity of skin. The Journal of Investigative Dermatology. 128: 776-82. PMID 18337710 DOI: 10.1038/Sj.Jid.5700986  1
2008 Adler AS, Kawahara TL, Segal E, Chang HY. Reversal of aging by NFkappaB blockade. Cell Cycle (Georgetown, Tex.). 7: 556-9. PMID 18256548 DOI: 10.4161/Cc.7.5.5490  1
2008 Sinha S, Adler AS, Field Y, Chang HY, Segal E. Systematic functional characterization of cis-regulatory motifs in human core promoters. Genome Research. 18: 477-88. PMID 18256240 DOI: 10.1101/Gr.6828808  1
2008 Rinn JL, Wang JK, Allen N, Brugmann SA, Mikels AJ, Liu H, Ridky TW, Stadler HS, Nusse R, Helms JA, Chang HY. A dermal HOX transcriptional program regulates site-specific epidermal fate. Genes & Development. 22: 303-7. PMID 18245445 DOI: 10.1101/gad.1610508  1
2008 Adler AS, Littlepage LE, Lin M, Kawahara TL, Wong DJ, Werb Z, Chang HY. CSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progression. Cancer Research. 68: 506-15. PMID 18199546 DOI: 10.1158/0008-5472.Can-07-3060  1
2008 Wong DJ, Nuyten DS, Regev A, Lin M, Adler AS, Segal E, van de Vijver MJ, Chang HY. Revealing targeted therapy for human cancer by gene module maps. Cancer Research. 68: 369-78. PMID 18199530 DOI: 10.1158/0008-5472.Can-07-0382  1
2007 Adler AS, Sinha S, Kawahara TL, Zhang JY, Segal E, Chang HY. Motif module map reveals enforcement of aging by continual NF-kappaB activity. Genes & Development. 21: 3244-57. PMID 18055696 DOI: 10.1101/Gad.1588507  1
2007 Lan F, Bayliss PE, Rinn JL, Whetstine JR, Wang JK, Chen S, Iwase S, Alpatov R, Issaeva I, Canaani E, Roberts TM, Chang HY, Shi Y. A histone H3 lysine 27 demethylase regulates animal posterior development. Nature. 449: 689-94. PMID 17851529 DOI: 10.1038/Nature06192  1
2007 Rinn JL, Kertesz M, Wang JK, Squazzo SL, Xu X, Brugmann SA, Goodnough LH, Helms JA, Farnham PJ, Segal E, Chang HY. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell. 129: 1311-23. PMID 17604720 DOI: 10.1016/J.Cell.2007.05.022  1
2007 Liu H, Adler AS, Segal E, Chang HY. A transcriptional program mediating entry into cellular quiescence. Plos Genetics. 3: e91. PMID 17559306 DOI: 10.1371/Journal.Pgen.0030091  1
2007 O'Geen H, Squazzo SL, Iyengar S, Blahnik K, Rinn JL, Chang HY, Green R, Farnham PJ. Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs. Plos Genetics. 3: e89. PMID 17542650 DOI: 10.1371/Journal.Pgen.0030089  1
2007 Segal E, Sirlin CB, Ooi C, Adler AS, Gollub J, Chen X, Chan BK, Matcuk GR, Barry CT, Chang HY, Kuo MD. Decoding global gene expression programs in liver cancer by noninvasive imaging. Nature Biotechnology. 25: 675-80. PMID 17515910 DOI: 10.1038/Nbt1306  1
2006 Chang HY, Thomson JA, Chen X. Microarray analysis of stem cells and differentiation. Methods in Enzymology. 420: 225-54. PMID 17161699 DOI: 10.1016/S0076-6879(06)20010-7  1
2006 DeVoss J, Hou Y, Johannes K, Lu W, Liou GI, Rinn J, Chang H, Caspi RR, Caspi R, Fong L, Anderson MS. Spontaneous autoimmunity prevented by thymic expression of a single self-antigen. The Journal of Experimental Medicine. 203: 2727-35. PMID 17116738 DOI: 10.1084/Jem.20061864  1
2006 Nuyten DS, Kreike B, Hart AA, Chi JT, Sneddon JB, Wessels LF, Peterse HJ, Bartelink H, Brown PO, Chang HY, van de Vijver MJ. Predicting a local recurrence after breast-conserving therapy by gene expression profiling. Breast Cancer Research : Bcr. 8: R62. PMID 17069664 DOI: 10.1186/Bcr1614  1
2006 Sneddon JB, Zhen HH, Montgomery K, van de Rijn M, Tward AD, West R, Gladstone H, Chang HY, Morganroth GS, Oro AE, Brown PO. Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 103: 14842-7. PMID 17003113 DOI: 10.1073/Pnas.0606857103  1
2006 Rinn JL, Bondre C, Gladstone HB, Brown PO, Chang HY. Anatomic demarcation by positional variation in fibroblast gene expression programs. Plos Genetics. 2: e119. PMID 16895450 DOI: 10.1371/Journal.Pgen.0020119  1
2006 Ray S, Atkuri KR, Deb-Basu D, Adler AS, Chang HY, Herzenberg LA, Felsher DW. MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species. Cancer Research. 66: 6598-605. PMID 16818632 DOI: 10.1158/0008-5472.Can-05-3115  1
2006 Adler AS, Chang HY. From description to causality: mechanisms of gene expression signatures in cancer. Cell Cycle (Georgetown, Tex.). 5: 1148-51. PMID 16721055 DOI: 10.4161/Cc.5.11.2798  1
2006 Adler AS, Lin M, Horlings H, Nuyten DS, van de Vijver MJ, Chang HY. Genetic regulators of large-scale transcriptional signatures in cancer. Nature Genetics. 38: 421-30. PMID 16518402 DOI: 10.1038/Ng1752  1
2005 Wong DJ, Chang HY. Learning more from microarrays: insights from modules and networks. The Journal of Investigative Dermatology. 125: 175-82. PMID 16098025 DOI: 10.1111/J.0022-202X.2005.23827.X  0.36
2005 Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sørlie T, Dai H, He YD, van't Veer LJ, Bartelink H, van de Rijn M, Brown PO, van de Vijver MJ. Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proceedings of the National Academy of Sciences of the United States of America. 102: 3738-43. PMID 15701700 DOI: 10.1073/Pnas.0409462102  1
2004 Chang HY, Sneddon JB, Alizadeh AA, Sood R, West RB, Montgomery K, Chi JT, van de Rijn M, Botstein D, Brown PO. Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. Plos Biology. 2: E7. PMID 14737219 DOI: 10.1371/Journal.Pbio.0020007  1
2003 Chi JT, Chang HY, Haraldsen G, Jahnsen FL, Troyanskaya OG, Chang DS, Wang Z, Rockson SG, van de Rijn M, Botstein D, Brown PO. Endothelial cell diversity revealed by global expression profiling. Proceedings of the National Academy of Sciences of the United States of America. 100: 10623-8. PMID 12963823 DOI: 10.1073/Pnas.1434429100  1
2003 Chi JT, Chang HY, Wang NN, Chang DS, Dunphy N, Brown PO. Genomewide view of gene silencing by small interfering RNAs. Proceedings of the National Academy of Sciences of the United States of America. 100: 6343-6. PMID 12730368 DOI: 10.1073/Pnas.1037853100  1
2002 Chang HY, Chi JT, Dudoit S, Bondre C, van de Rijn M, Botstein D, Brown PO. Diversity, topographic differentiation, and positional memory in human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 99: 12877-82. PMID 12297622 DOI: 10.1073/Pnas.162488599  1
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