Douglas A. Lappi, Ph.D. - Publications

Advanced Targeting Systems 
Toxins, ribosome-inactivating proteins

93 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Lappi DA, Feldman J, Sengelaub D, McGaughy J. Nervous System Research with RIP Conjugates: From Determination of Function to Therapy Ribosome-Inactivating Proteins: Ricin and Related Proteins. 253-269. DOI: 10.1002/9781118847237.ch17  1
2014 Lappi DA, Stirpe F. Ribosome-inactivating Proteins in Cancer Treatment Ribosome-Inactivating Proteins: Ricin and Related Proteins. 244-252. DOI: 10.1002/9781118847237.ch16  1
2014 Stirpe F, Lappi DA. Ribosome-inactivating proteins: Ricin and related proteins Ribosome-Inactivating Proteins: Ricin and Related Proteins. 1-296. DOI: 10.1002/9781118847237  1
2013 Wiese AJ, Rathbun M, Butt MT, Malkmus SA, Richter PJ, Osborn KG, Xu Q, Veesart SL, Steinauer JJ, Higgins D, Lappi DA, Russell B, Yaksh TL. Intrathecal substance P-saporin in the dog: distribution, safety, and spinal neurokinin-1 receptor ablation. Anesthesiology. 119: 1163-77. PMID 24051388 DOI: 10.1097/ALN.0b013e3182a95164  1
2011 Laplante F, Lappi DA, Sullivan RM. Cholinergic depletion in the nucleus accumbens: effects on amphetamine response and sensorimotor gating. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35: 501-9. PMID 21163316 DOI: 10.1016/j.pnpbp.2010.12.005  1
2008 Göz D, Studholme K, Lappi DA, Rollag MD, Provencio I, Morin LP. Targeted destruction of photosensitive retinal ganglion cells with a saporin conjugate alters the effects of light on mouse circadian rhythms. Plos One. 3: e3153. PMID 18773079 DOI: 10.1371/journal.pone.0003153  1
2006 Allen JW, Mantyh PW, Horais K, Tozier N, Rogers SD, Ghilardi JR, Cizkova D, Grafe MR, Richter P, Lappi DA, Yaksh TL. Safety evaluation of intrathecal substance P-saporin, a targeted neurotoxin, in dogs. Toxicological Sciences : An Official Journal of the Society of Toxicology. 91: 286-98. PMID 16500924 DOI: 10.1093/toxsci/kfj143  1
2005 Wiley RG, Lappi DA. Saporin conjugates and pain Molecular Neurosurgery With Targeted Toxins. 235-248. DOI: 10.1007/978-1-59259-896-0_10  1
2005 Wiley RG, Lappi DA. Introduction to molecular neurosurgery Molecular Neurosurgery With Targeted Toxins. 1-8. DOI: 10.1007/978-1-59259-896-0_1  1
2005 Wiley RG, Lappi DA. Molecular neurosurgery with targeted toxins Molecular Neurosurgery With Targeted Toxins. 1-311. DOI: 10.1007/978-1-59259-896-0  1
2004 Lappi DA, Wiley RG. Immunotoxins and neuropeptide-toxin conjugates experimental applications. Mini Reviews in Medicinal Chemistry. 4: 585-95. PMID 15180512  1
2004 Yezierski RP, Yu CG, Mantyh PW, Vierck CJ, Lappi DA. Spinal neurons involved in the generation of at-level pain following spinal injury in the rat. Neuroscience Letters. 361: 232-6. PMID 15135936 DOI: 10.1016/j.neulet.2003.12.035  1
2004 Nattie EE, Li A, Richerson GB, Richerson G, Lappi DA. Medullary serotonergic neurones and adjacent neurones that express neurokinin-1 receptors are both involved in chemoreception in vivo. The Journal of Physiology. 556: 235-53. PMID 14724193 DOI: 10.1113/jphysiol.2003.059766  1
2003 Wiley RG, Harrison MB, Levey AI, Lappi DA. Destruction of midbrain dopaminergic neurons by using immunotoxin to dopamine transporter. Cellular and Molecular Neurobiology. 23: 839-50. PMID 14514035 DOI: 10.1023/A:1025065306264  1
2003 Wiley RG, Lappi DA. Targeted toxins in pain. Advanced Drug Delivery Reviews. 55: 1043-54. PMID 12935943 DOI: 10.1016/S0169-409X(03)00102-9  1
2001 Wiley RG, Lappi DA. Targeted toxins. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit1.7. PMID 18428453 DOI: 10.1002/0471142301.ns0107s14  1
2001 Berger-Sweeney J, Stearns NA, Murg SL, Floerke-Nashner LR, Lappi DA, Baxter MG. Selective immunolesions of cholinergic neurons in mice: effects on neuroanatomy, neurochemistry, and behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 8164-73. PMID 11588189  1
2001 Gerashchenko D, Kohls MD, Greco M, Waleh NS, Salin-Pascual R, Kilduff TS, Lappi DA, Shiromani PJ. Hypocretin-2-saporin lesions of the lateral hypothalamus produce narcoleptic-like sleep behavior in the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7273-83. PMID 11549737  1
2001 Porreca F, Burgess SE, Gardell LR, Vanderah TW, Malan TP, Ossipov MH, Lappi DA, Lai J. Inhibition of neuropathic pain by selective ablation of brainstem medullary cells expressing the mu-opioid receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5281-8. PMID 11438603  1
2000 Jasmin L, Janni G, Moallem TM, Lappi DA, Ohara PT. Schwann cells are removed from the spinal cord after effecting recovery from paraplegia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 9215-23. PMID 11124999  1
2000 Lappi DA, Wiley RG. Entering through the doors of perception: characterization of a highly selective Substance P receptor-targeted toxin. Neuropeptides. 34: 323-8. PMID 11049736 DOI: 10.1054/npep.2000.0827  1
2000 Maciejewski-Lenoir D, Heinrichs SC, Liu XJ, Ling N, Tucker A, Xie Q, Lappi DA, Grigoriadis DE. Selective impairment of corticotropin-releasing factor1 (CRF1) receptor-mediated function using CRF coupled to saporin. Endocrinology. 141: 498-504. PMID 10650928 DOI: 10.1210/endo.141.2.7336  1
2000 Kohls MD, Lappi DA. Mab-ZAP: a tool for evaluating antibody efficacy for use in an immunotoxin. Biotechniques. 28: 162-5. PMID 10649788  1
1999 Wiley RG, Lappi DA. Targeting neurokinin-1 receptor-expressing neurons with [Sar9,Met(O2)11 substance P-saporin. Neuroscience Letters. 277: 1-4. PMID 10643883 DOI: 10.1016/S0304-3940(99)00846-0  1
1999 Wrenn CC, Lappi DA, Wiley RG. Threshold relationship between lesion extent of the cholinergic basal forebrain in the rat and working memory impairment in the radial maze. Brain Research. 847: 284-98. PMID 10575099 DOI: 10.1016/S0006-8993(99)02099-5  1
1999 Nichols ML, Allen BJ, Rogers SD, Ghilardi JR, Honore P, Luger NM, Finke MP, Li J, Lappi DA, Simone DA, Mantyh PW. Transmission of chronic nociception by spinal neurons expressing the substance P receptor. Science (New York, N.Y.). 286: 1558-61. PMID 10567262 DOI: 10.1126/science.286.5444.1558  1
1998 Zhang ZJ, Lappi DA, Wrenn CC, Milner TA, Wiley RG. Selective lesion of the cholinergic basal forebrain causes a loss of cortical neuropeptide Y and somatostatin neurons. Brain Research. 800: 198-206. PMID 9685641 DOI: 10.1016/S0006-8993(98)00484-3  1
1998 Blessing WW, Lappi DA, Wiley RG. Destruction of locus coeruleus neuronal perikarya after injection of anti-dopamine-B-hydroxylase immunotoxin into the olfactory bulb of the rat. Neuroscience Letters. 243: 85-8. PMID 9535119 DOI: 10.1016/S0304-3940(98)00090-1  1
1997 Mantyh PW, Rogers SD, Honore P, Allen BJ, Ghilardi JR, Li J, Daughters RS, Lappi DA, Wiley RG, Simone DA. Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor. Science (New York, N.Y.). 278: 275-9. PMID 9323204 DOI: 10.1126/science.278.5336.275  1
1997 Wiley RG, Lappi DA. Destruction of neurokinin-1 receptor expressing cells in vitro and in vivo using substance P-saporin in rats. Neuroscience Letters. 230: 97-100. PMID 9259473 DOI: 10.1016/S0304-3940(97)00490-4  1
1997 Ohtake T, Heckers S, Wiley RG, Lappi DA, Mesulam MM, Geula C. Retrograde degeneration and colchicine protection of basal forebrain cholinergic neurons following hippocampal injections of an immunotoxin against the P75 nerve growth factor receptor. Neuroscience. 78: 123-33. PMID 9135094 DOI: 10.1016/S0306-4522(96)00520-9  1
1996 Wrenn CC, Picklo MJ, Lappi DA, Robertson D, Wiley RG. Central noradrenergic lesioning using anti-DBH-saporin: anatomical findings. Brain Research. 740: 175-84. PMID 8973812 DOI: 10.1016/S0006-8993(96)00855-4  1
1996 Biro S, Shrivastav S, Yu ZX, Lappi DA, Baird A, Casscells W. Stimulation of endothelial cells by doses of basic FGF-saporin that are lethal to smooth muscle cells Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents. 3: 155-163.  1
1996 Robinson JK, Wenk GL, Wiley RG, Lappi DA, Crawley JN. 192IgG-Saporin immunotoxin and ibotenic acid lesions of nucleus basalis and medial septum produce comparable deficits on delayed nonmatching to position in rats Psychobiology. 24: 179-186.  1
1995 Davol P, Beitz JG, Mohler M, Ying W, Cook J, Lappi DA, Frackelton AR. Saporin toxins directed to basic fibroblast growth factor receptors effectively target human ovarian teratocarcinoma in an animal model. Cancer. 76: 79-85. PMID 8630880 DOI: 10.1002/1097-0142(19950701)76:1<79::AID-CNCR2820760111>3.0.CO;2-G  1
1995 Lappi DA. Tumor targeting through fibroblast growth factor receptors. Seminars in Cancer Biology. 6: 279-88. PMID 8562905 DOI: 10.1006/scbi.1995.0036  1
1995 Waite JJ, Chen AD, Wardlow ML, Wiley RG, Lappi DA, Thal LJ. 192 immunoglobulin G-saporin produces graded behavioral and biochemical changes accompanying the loss of cholinergic neurons of the basal forebrain and cerebellar Purkinje cells. Neuroscience. 65: 463-76. PMID 7777161 DOI: 10.1016/0306-4522(94)00479-O  1
1995 Wiley RG, Berbos TG, Deckwerth TL, Johnson EM, Lappi DA. Destruction of the cholinergic basal forebrain using immunotoxin to rat NGF receptor: modeling the cholinergic degeneration of Alzheimer's disease. Journal of the Neurological Sciences. 128: 157-66. PMID 7738592 DOI: 10.1016/0022-510X(94)00226-E  1
1995 Picklo MJ, Wiley RG, Lonce S, Lappi DA, Robertson D. Anti-dopamine beta-hydroxylase immunotoxin-induced sympathectomy in adult rats. The Journal of Pharmacology and Experimental Therapeutics. 275: 1003-10. PMID 7473126  1
1994 Lappi DA, Ying W, Barthelemy I, Martineau D, Prieto I, Benatti L, Soria M, Baird A. Expression and activities of a recombinant basic fibroblast growth factor-saporin fusion protein. The Journal of Biological Chemistry. 269: 12552-8. PMID 8175664  1
1994 Gonzalez AM, Logan A, Ying W, Lappi DA, Berry M, Baird A. Fibroblast growth factor in the hypothalamic-pituitary axis: differential expression of fibroblast growth factor-2 and a high affinity receptor. Endocrinology. 134: 2289-97. PMID 8156932 DOI: 10.1210/endo.134.5.8156932  1
1994 Heckers S, Ohtake T, Wiley RG, Lappi DA, Geula C, Mesulam MM. Complete and selective cholinergic denervation of rat neocortex and hippocampus but not amygdala by an immunotoxin against the p75 NGF receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 1271-89. PMID 8120624  1
1994 Waite JJ, Wardlow ML, Chen AC, Lappi DA, Wiley RG, Thal LJ. Time course of cholinergic and monoaminergic changes in rat brain after immunolesioning with 192 IgG-saporin. Neuroscience Letters. 169: 154-8. PMID 8047273 DOI: 10.1016/0304-3940(94)90379-4  1
1994 Ying W, Martineau D, Beitz J, Lappi DA, Baird A. Anti-B16-F10 melanoma activity of a basic fibroblast growth factor-saporin mitotoxin. Cancer. 74: 848-53. PMID 8039113 DOI: 10.1002/1097-0142(19940801)74:3<848::AID-CNCR2820740310>3.0.CO;2-J  1
1994 Berger-Sweeney J, Heckers S, Mesulam MM, Wiley RG, Lappi DA, Sharma M. Differential effects on spatial navigation of immunotoxin-induced cholinergic lesions of the medial septal area and nucleus basalis magnocellularis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 4507-19. PMID 8027790  1
1994 Torres EM, Perry TA, Blockland A, Wilkinson LS, Wiley RG, Lappi DA, Dunnet SB. Behavioural, histochemical and biochemical consequences of selective immunolesions in discrete regions of the basal forebrain cholinergic system. Neuroscience. 63: 95-122. PMID 7898665 DOI: 10.1016/0306-4522(94)90010-8  1
1994 Picklo MJ, Wiley RG, Lappi DA, Robertson D. Noradrenergic lesioning with an anti-dopamine beta-hydroxylase immunotoxin. Brain Research. 666: 195-200. PMID 7882029 DOI: 10.1016/0006-8993(94)90772-2  1
1994 Holley LA, Wiley RG, Lappi DA, Sarter M. Cortical cholinergic deafferentation following the intracortical infusion of 192 IgG-saporin: a quantitative histochemical study. Brain Research. 663: 277-86. PMID 7874512 DOI: 10.1016/0006-8993(94)91274-2  1
1993 Casscells W, Lappi DA, Baird A. Molecular atherectomy for restenosis. Trends in Cardiovascular Medicine. 3: 235-43. PMID 21244914 DOI: 10.1016/1050-1738(93)90045-8  1
1993 Barthelemy I, Martineau D, Ong M, Matsunami R, Ling N, Benatti L, Cavallaro U, Soria M, Lappi DA. The expression of saporin, a ribosome-inactivating protein from the plant Saponaria officinalis, in Escherichia coli. The Journal of Biological Chemistry. 268: 6541-8. PMID 8454624  1
1993 Lappi DA, Martineau D, Sarmientos P, Garofano L, Aranda AP, Miyajima A, Kitamura T, Baird A. Characterization of a saporin mitotoxin specifically cytotoxic to cells bearing the granulocyte-macrophage colony-stimulating factor receptor. Growth Factors (Chur, Switzerland). 9: 31-9. PMID 8347350 DOI: 10.3109/08977199308991580  1
1993 Cavallaro U, del Vecchio A, Lappi DA, Soria MR. A conjugate between human urokinase and saporin, a type-1 ribosome-inactivating protein, is selectively cytotoxic to urokinase receptor-expressing cells. The Journal of Biological Chemistry. 268: 23186-90. PMID 8226837  1
1993 Lappi DA, Matsunami R, Martineau D, Baird A. Reducing the heterogeneity of chemically conjugated targeted toxins: homogeneous basic FGF-saporin. Analytical Biochemistry. 212: 446-51. PMID 8214586 DOI: 10.1006/abio.1993.1353  1
1992 Soria MR, Benatti L, Nitti G, Ceriotti A, Solinas M, Lappi DA, Lorenzetti R. Studies on ribosome-inactivating proteins from Saponaria officinalis. Targeted Diagnosis and Therapy. 7: 193-212. PMID 1633290  1
1992 Nilsson OG, Leanza G, Rosenblad C, Lappi DA, Wiley RG, Björklund A. Spatial learning impairments in rats with selective immunolesion of the forebrain cholinergic system. Neuroreport. 3: 1005-8. PMID 1482757  1
1992 David T, Tassin J, Lappi DA, Baird A, Courtois Y. Biphasic effect of the mitotoxin bFGF-saporin on bovine lens epithelial cell growth: effect of cell density and extracellular matrix. Journal of Cellular Physiology. 153: 483-90. PMID 1447311 DOI: 10.1002/jcp.1041530307  1
1992 Stirpe F, Barbieri L, Battelli MG, Soria M, Lappi DA. Ribosome-inactivating proteins from plants: present status and future prospects. Bio/Technology (Nature Publishing Company). 10: 405-12. PMID 1368484 DOI: 10.1038/nbt0492-405  1
1992 Gonzalez AM, Buscaglia M, Fox R, Isacchi A, Sarmientos P, Farris J, Ong M, Martineau D, Lappi DA, Baird A. Basic fibroblast growth factor in Dupuytren's contracture. The American Journal of Pathology. 141: 661-71. PMID 1325742  1
1992 Casscells W, Lappi DA, Olwin BB, Wai C, Siegman M, Speir EH, Sasse J, Baird A. Elimination of smooth muscle cells in experimental restenosis: targeting of fibroblast growth factor receptors. Proceedings of the National Academy of Sciences of the United States of America. 89: 7159-63. PMID 1323129 DOI: 10.1073/pnas.89.15.7159  1
1992 Lappi DA, Martineau D, Maher PA, Florkiewicz RZ, Buscaglia M, Gonzalez AM, Farris J, Hamer M, Fox R, Baird A. Basic fibroblast growth factor in cells derived from Dupuytren's contracture: synthesis, presence, and implications for treatment of the disease. The Journal of Hand Surgery. 17: 324-32. PMID 1314273 DOI: 10.1016/0363-5023(92)90415-L  1
1992 Beitz JG, Davol P, Clark JW, Kato J, Medina M, Frackelton AR, Lappi DA, Baird A, Calabresi P. Antitumor activity of basic fibroblast growth factor-saporin mitotoxin in vitro and in vivo. Cancer Research. 52: 227-30. PMID 1309225  1
1992 Stirpe F, Barbieri L, Battelli MG, Soria M, Lappi DA. Ribosome-inctivating proteins from plants: Present status and future prospects Nature Biotechnology. 10: 405-412.  1
1991 Beattie GM, Lappi DA, Baird A, Hayek A. Functional impact of attachment and purification in the short term culture of human pancreatic islets. The Journal of Clinical Endocrinology and Metabolism. 73: 93-8. PMID 2045476 DOI: 10.1210/jcem-73-1-93  1
1991 Lindner V, Lappi DA, Baird A, Majack RA, Reidy MA. Role of basic fibroblast growth factor in vascular lesion formation. Circulation Research. 68: 106-13. PMID 1984855  1
1991 Martineau D, Lappi DA, Amburn E, Baird A. Basic fibroblast growth factor-saporin mitotoxin. In vitro studies of its cell-killing activity and of substances that alter that activity. Annals of the New York Academy of Sciences. 638: 438-41. PMID 1785818  1
1991 Prieto I, Lappi DA, Ong M, Matsunami R, Benatti L, Villares R, Soria M, Sarmientos P, Baird A. Expression and characterization of a basic fibroblast growth factor-saporin fusion protein in Escherichia coli. Annals of the New York Academy of Sciences. 638: 434-7. PMID 1785817  1
1991 Wiley RG, Oeltmann TN, Lappi DA. Immunolesioning: selective destruction of neurons using immunotoxin to rat NGF receptor. Brain Research. 562: 149-53. PMID 1666014 DOI: 10.1016/0006-8993(91)91199-B  1
1991 Gonzalez AM, Lappi DA, Buscaglia ML, Carman LS, Gage FH, Baird A. Basic FGF-SAP mitotoxin in the hippocampus. Specific lethal effect on cells expressing the basic FGF receptor. Annals of the New York Academy of Sciences. 638: 442-4. PMID 1664696 DOI: 10.1111/j.1749-6632.1991.tb49064.x  1
1991 Lappi DA, Maher PA, Martineau D, Baird A. The basic fibroblast growth factor-saporin mitotoxin acts through the basic fibroblast growth factor receptor. Journal of Cellular Physiology. 147: 17-26. PMID 1645359 DOI: 10.1002/jcp.1041470104  1
1990 Beattie GM, Lappi DA, Baird A, Hayek A. Selective elimination of fibroblasts from pancreatic islet monolayers by basic fibroblast growth factor-saporin mitotoxin. Diabetes. 39: 1002-5. PMID 2165003  1
1990 Lappi DA, Baird A. Mitotoxins: growth factor-targeted cytotoxic molecules. Progress in Growth Factor Research. 2: 223-36. PMID 2133290 DOI: 10.1016/0955-2235(90)90020-K  1
1989 Barbieri L, Bolognesi A, Cenini P, Falasca AI, Minghetti A, Garofano L, Guicciardi A, Lappi D, Miller SP, Stirpe F. Ribosome-inactivating proteins from plant cells in culture Biochemical Journal. 257: 801-807. PMID 2930487  1
1989 Siena S, Bregni M, Formosa A, Brando B, Marenco P, Lappi DA, Bonadonna G, Gianni AM. Immunotoxin-mediated inhibition of chronic lymphocytic leukemia cell proliferation in humans. Cancer Research. 49: 3328-32. PMID 2785850  1
1989 Montecucchi PC, Lazzarini AM, Barbieri L, Stirpe F, Soria M, Lappi D. N-terminal sequence of some ribosome-inactivating proteins International Journal of Peptide and Protein Research. 33: 263-267. PMID 2753596  1
1989 Barbieri L, Bolognesi A, Dinota A, Lappi DA, Soria M, Tazzari PL, Stirpe F. Selective killing of CD4+ and CD8+ cells with immunotoxins containing saporin. Scandinavian Journal of Immunology. 30: 369-72. PMID 2571186  1
1989 Marcucci F, Lappi DA, Ghislieri M, Martineau D, Formosa A, Siena S, Bregni M, Soria M, Gianni AM. In vivo effects in mice of an anti-T cell immunotoxin. Journal of Immunology (Baltimore, Md. : 1950). 142: 2955-60. PMID 2564860  1
1989 Benatti L, Saccardo MB, Dani M, Nitti G, Sassano M, Lorenzetti R, Lappi DA, Soria M. Nucleotide sequence of cDNA coding for saporin-6, a type-1 ribosome-inactivating protein from Saponaria officinalis. European Journal of Biochemistry / Febs. 183: 465-70. PMID 2547612  1
1989 Lappi DA, Martineau D, Baird A. Biological and chemical characterization of basic FGF-saporin mitotoxin. Biochemical and Biophysical Research Communications. 160: 917-23. PMID 2541718 DOI: 10.1016/0006-291X(89)92522-9  1
1989 Siena S, Bregni M, Formosa A, Brando B, Lappi DA, Bonadonna G, Gianni AM. Immunotoxin mediated killing of clonable T-lymphocytes infiltrating an irreversibly rejected human renal allograft. Journal of Biological Regulators and Homeostatic Agents. 3: 84-8. PMID 2479229  1
1989 Bregni M, Siena S, Formosa A, Lappi DA, Martineau D, Malavasi F, Dorken B, Bonadonna G, Gianni AM. B-cell restricted saporin immunotoxins: activity against B-cell lines and chronic lymphocytic leukemia cells. Blood. 73: 753-62. PMID 2465042  1
1988 Siena S, Bregni M, Formosa A, Martineau D, Lappi DA, Bonadonna G, Gianni AM. Evaluation of antihuman T lymphocyte saporin immunotoxins potentially useful in human transplantation. Transplantation. 46: 747-53. PMID 3264092  1
1988 Bregni M, Lappi DA, Siena S, Formosa A, Villa S, Soria M, Bonadonna G, Gianni AM. Activity of a monoclonal antibody-saporin-6 conjugate against B-lymphoma cells. Journal of the National Cancer Institute. 80: 511-7. PMID 3259267  1
1988 Bergamaschi G, Cazzola M, Dezza L, Savino E, Consonni L, Lappi D. Killing of K562 cells with conjugates between human transferrin and a ribosome-inactivating protein (SO-6) British Journal of Haematology. 68: 379-384. PMID 3162685  1
1988 Siena S, Lappi DA, Bregni M, Formosa A, Villa S, Soria M, Bonadonna G, Gianni AM. Synthesis and characterization of an antihuman T-lymphocyte saporin immunotoxin (OKT1-SAP) with in vivo stability into nonhuman primates. Blood. 72: 756-65. PMID 3042047  1
1986 Lorenzetti R, Sidoli A, Palomba R, Monaco L, Martineau D, Lappi DA, Soria M. Expression of the human apolipoprotein AI gene fused to the E. coli gene for beta-galactosidase. Febs Letters. 194: 343-6. PMID 3079712 DOI: 10.1016/0014-5793(86)80114-4  1
1985 Lappi DA, Esch FS, Barbieri L, Stirpe F, Soria M. Characterization of a Saponaria officinalis seed ribosome-inactivating protein: immunoreactivity and sequence homologies. Biochemical and Biophysical Research Communications. 129: 934-42. PMID 3925952 DOI: 10.1016/0006-291X(85)91981-3  1
1985 Lorenzetti R, Dani M, Lappi DA, Martineau D, Casati M, Monaco L, Shatzman A, Rosenberg M, Soria M. Plasmid pFCE4: a new system of Escherichia coli expression-modification vectors. Gene. 39: 85-7. PMID 3908223 DOI: 10.1016/0378-1119(85)90111-8  1
1980 Lappi DA, Evans FE, Kaplan NO. Reduced nicotinamide 8-(alkylamino)adenine dinucleotides: enzyme-coenzyme interactions with different adenyl glycosyl bond conformations. Biochemistry. 19: 3841-5. PMID 6773554  0.84
1979 Kapmeyer H, Lappi DA, Kaplan NO. The synthesis of 8-(6-aminohexyl)-amino-GTP and -GDP and their application as ligands in affinity chromatography. Analytical Biochemistry. 99: 189-99. PMID 532959 DOI: 10.1016/0003-2697(79)90062-9  0.84
1978 Lappi DA, Kapmeyer W, Beglau JM, Kaplan NO. The disulfide bond connecting the chains of ricin. Proceedings of the National Academy of Sciences of the United States of America. 75: 1096-100. PMID 274699  0.84
1977 Everse J, Lappi DA, Beglau JM, Lee CL, Kaplan NO. Investigations into the relationship between structure and function of diphtheria toxin. Proceedings of the National Academy of Sciences of the United States of America. 74: 472-6. PMID 403520 DOI: 10.1073/pnas.74.2.472  0.84
1976 Lappi DA, Stolzenbach FE, Kaplan NO, Kamen MD. Immobilization of hydrogenase on glass beads. Biochemical and Biophysical Research Communications. 69: 878-84. PMID 819014 DOI: 10.1016/0006-291X(76)90455-1  0.84
1974 Lee CY, Lappi DA, Wermuth B, Everse J, Kaplan NO. 8-(6-Aminohexyl)-amino-adenine nucleotide derivatives for affinity chromatography. Archives of Biochemistry and Biophysics. 163: 561-9. PMID 4370563 DOI: 10.1016/0003-9861(74)90515-3  0.84
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