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Nadja B. Cech, Ph.D. - Publications

Affiliations: 
2001- Chemistry  University of North Carolina at Greensboro, Greensboro, NC, United States 
Area:
Mass spectrometry, botany
Website:
https://www.uncg.edu/che/faculty/cech/team.html

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Clark TN, Houriet J, Vidar WS, Kellogg JJ, Todd DA, Cech NB, Linington RG. Interlaboratory Comparison of Untargeted Mass Spectrometry Data Uncovers Underlying Causes for Variability. Journal of Natural Products. PMID 33666420 DOI: 10.1021/acs.jnatprod.0c01376  0.8
2021 Khin M, Knowles SL, Crandall WJ, Jones DD, Oberlies NH, Cech NB, Houriet J. Capturing the antimicrobial profile of Rosmarinus officinalis against methicillin-resistant Staphylococcus aureus (MRSA) with bioassay-guided fractionation and bioinformatics. Journal of Pharmaceutical and Biomedical Analysis. 197: 113965. PMID 33640687 DOI: 10.1016/j.jpba.2021.113965  0.8
2020 Nguyen JT, Tian DD, Tanna RS, Hadi DL, Bansal S, Calamia JC, Arian CM, Shireman LM, Molnár B, Horváth M, Kellogg JJ, Layton ME, White JR, Cech NB, Boyce RD, et al. Assessing Transporter-Mediated Natural Product-Drug Interactions via In vitro-In vivo Extrapolation: Clinical Evaluation with a Probe Cocktail. Clinical Pharmacology and Therapeutics. PMID 33174626 DOI: 10.1002/cpt.2107  0.8
2020 Tanna RS, Tian DD, Cech NB, Oberlies NH, Rettie AE, Thummel KE, Paine MF. Refined prediction of pharmacokinetic kratom-drug interactions: time-dependent inhibition considerations. The Journal of Pharmacology and Experimental Therapeutics. PMID 33093187 DOI: 10.1124/jpet.120.000270  0.8
2020 Jones DD, Caesar LK, Pelzer CV, Crandall WJ, Jenul C, Todd DA, Horswill AR, Cech NB. Targeted and untargeted analysis of secondary metabolites to monitor growth and quorum sensing inhibition for methicillin-resistant Staphylococcus aureus (MRSA). Journal of Microbiological Methods. 106000. PMID 32649968 DOI: 10.1016/J.Mimet.2020.106000  0.68
2020 Khin M, Cech NB, Kellogg JJ, Caesar LK. Chemical Evaluation of the Effects of Storage Conditions on the Botanical Goldenseal using Marker-based and Metabolomics Approaches. The Yale Journal of Biology and Medicine. 93: 265-275. PMID 32607087  0.8
2020 Flores-Bocanegra L, Raja HA, Graf TN, Augustinović M, Wallace ED, Hematian S, Kellogg JJ, Todd DA, Cech NB, Oberlies NH. The Chemistry of Kratom []: Updated Characterization Data and Methods to Elucidate Indole and Oxindole Alkaloids. Journal of Natural Products. PMID 32597657 DOI: 10.1021/Acs.Jnatprod.0C00257  0.8
2020 Wallace ED, Todd DA, Harnly JM, Cech NB, Kellogg JJ. Identification of adulteration in botanical samples with untargeted metabolomics. Analytical and Bioanalytical Chemistry. PMID 32347364 DOI: 10.1007/S00216-020-02678-6  0.8
2020 Schilcher K, Caesar LK, Cech NB, Horswill AR. Processing, Export, and Identification of Novel Linear Peptides from Staphylococcus aureus. Mbio. 11. PMID 32291297 DOI: 10.1128/Mbio.00112-20  0.68
2020 Brown MM, Kwiecinski JM, Mejia Cruz L, Shahbandi A, Todd DA, Cech NB, Horswill AR. Novel peptide from commensal blocks MRSA quorum sensing and protects host skin from damage. Antimicrobial Agents and Chemotherapy. PMID 32253213 DOI: 10.1128/Aac.00172-20  0.56
2020 Kellogg JJ, Kvalheim OM, Cech NB. Composite score analysis for unsupervised comparison and network visualization of metabolomics data. Analytica Chimica Acta. 1095: 38-47. PMID 31864629 DOI: 10.1016/J.Aca.2019.10.029  0.8
2019 Rivera-Chávez J, Caesar L, Garcia-Salazar JJ, Raja HA, Cech NB, Pearce CJ, Oberlies NH. Mycopyranone: a 8,8'-binaphthopyranone with potent anti-MRSA activity from the fungus sp. Tetrahedron Letters. 60: 594-597. PMID 31598014 DOI: 10.1016/J.Tetlet.2019.01.029  0.8
2019 Caesar LK, Nogo S, Naphen CN, Cech NB. Simplify: A Mass Spectrometry Metabolomics Approach to Identify Additives and Synergists from Complex Mixtures. Analytical Chemistry. PMID 31365233 DOI: 10.1021/Acs.Analchem.9B02377  0.68
2019 Caesar LK, Cech NB. Synergy and antagonism in natural product extracts: when 1 + 1 does not equal 2. Natural Product Reports. PMID 31187844 DOI: 10.1039/C9Np00011A  0.68
2019 Williams MR, Costa SK, Zaramela LS, Khalil S, Todd DA, Winter HL, Sanford JA, O'Neill AM, Liggins MC, Nakatsuji T, Cech NB, Cheung AL, Zengler K, Horswill AR, Gallo RL. Quorum sensing between bacterial species on the skin protects against epidermal injury in atopic dermatitis. Science Translational Medicine. 11. PMID 31043573 DOI: 10.1126/Scitranslmed.Aat8329  0.56
2019 Parlet CP, Kavanaugh JS, Crosby HA, Raja HA, El-Elimat T, Todd DA, Pearce CJ, Cech NB, Oberlies NH, Horswill AR. Apicidin Attenuates MRSA Virulence through Quorum-Sensing Inhibition and Enhanced Host Defense. Cell Reports. 27: 187-198.e6. PMID 30943400 DOI: 10.1016/J.Celrep.2019.03.018  0.8
2019 Caesar LK, Kellogg JJ, Kvalheim OM, Cech NB. Opportunities and Limitations for Untargeted Mass Spectrometry Metabolomics to Identify Biologically Active Constituents in Complex Natural Product Mixtures. Journal of Natural Products. PMID 30844279 DOI: 10.1021/Acs.Jnatprod.9B00176  0.8
2019 Knowles SL, Raja HA, Wright AJ, Lee AML, Caesar LK, Cech NB, Mead ME, Steenwyk JL, Ries LNA, Goldman GH, Rokas A, Oberlies NH. Mapping the Fungal Battlefield: Using Chemistry and Deletion Mutants to Monitor Interspecific Chemical Interactions Between Fungi. Frontiers in Microbiology. 10: 285. PMID 30837981 DOI: 10.3389/Fmicb.2019.00285  0.8
2019 Marroquin S, Gimza B, Tomlinson B, Stein M, Frey A, Keogh RA, Zapf R, Todd DA, Cech NB, Carroll RK, Shaw LN. MroQ is a Novel Abi-domain Protein That Influences Virulence Gene Expression in via Modulation of Agr Activity. Infection and Immunity. PMID 30833335 DOI: 10.1128/Iai.00002-19  0.56
2019 Paguigan ND, Rivera-Chávez J, Stempin JJ, Augustinović M, Noras AI, Raja HA, Todd DA, Triplett KD, Day C, Figueroa M, Hall PR, Cech NB, Oberlies NH. Prenylated Diresorcinols Inhibit Bacterial Quorum Sensing. Journal of Natural Products. PMID 30730742 DOI: 10.1021/Acs.Jnatprod.8B00925  0.8
2019 Kellogg JJ, Paine MF, McCune JS, Oberlies NH, Cech NB. Selection and characterization of botanical natural products for research studies: a NaPDI center recommended approach. Natural Product Reports. PMID 30681109 DOI: 10.1039/C8Np00065D  0.8
2018 Khin M, Jones AM, Cech NB, Caesar LK. Phytochemical Analysis and Antimicrobial Efficacy of against Extensively Drug-Resistant . Natural Product Communications. 13. PMID 31080542 DOI: 10.1177/1934578X1801301117  0.68
2018 Bruni R, Brighenti V, Caesar LK, Bertelli D, Cech NB, Pellati F. Analytical methods for the study of bioactive compounds from medicinally used Echinacea species. Journal of Pharmaceutical and Biomedical Analysis. 160: 443-477. PMID 30142565 DOI: 10.1016/J.Jpba.2018.07.044  0.68
2018 Wallace ED, Oberlies NH, Cech NB, Kellogg JJ. Detection of adulteration in Hydrastis canadensis (goldenseal) dietary supplements via untargeted mass spectrometry-based metabolomics. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. PMID 30031041 DOI: 10.1016/J.Fct.2018.07.033  0.8
2018 Caesar LK, Kvalheim OM, Cech NB. Hierarchical cluster analysis of technical replicates to identify interferents in untargeted mass spectrometry metabolomics. Analytica Chimica Acta. 1021: 69-77. PMID 29681286 DOI: 10.1016/J.Aca.2018.03.013  0.68
2018 Caesar LK, Kellogg JJ, Kvalheim OM, Cech RA, Cech NB. Integration of Biochemometrics and Molecular Networking to Identify Antimicrobials in Angelica keiskei. Planta Medica. PMID 29571174 DOI: 10.1055/A-0590-5223  0.8
2018 Tian DD, Kellogg JJ, Okut N, Oberlies NH, Cech NB, Shen DD, McCune JS, Paine MF. Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea () Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29467215 DOI: 10.1124/Dmd.117.079491  0.8
2017 Paharik AE, Parlet CP, Chung N, Todd DA, Rodriguez EI, Van Dyke MJ, Cech NB, Horswill AR. Coagulase-Negative Staphylococcal Strain Prevents Staphylococcus aureus Colonization and Skin Infection by Blocking Quorum Sensing. Cell Host & Microbe. 22: 746-756.e5. PMID 29199097 DOI: 10.1016/J.Chom.2017.11.001  0.56
2017 Britton ER, Kellogg JJ, Kvalheim OM, Cech NB. Biochemometrics to Identify Synergists and Additives from Botanical Medicines: A Case Study with Hydrastis canadensis (Goldenseal). Journal of Natural Products. PMID 29091439 DOI: 10.1021/Acs.Jnatprod.7B00654  0.8
2017 Gulledge TV, Collette NM, Mackey E, Johnstone SE, Moazami Y, Todd DA, Moeser AJ, Pierce JG, Cech NB, Laster SM. Mast cell degranulation and calcium influx are inhibited by an Echinacea purpurea extract and the alkylamide dodeca-2E,4E-dienoic acid isobutylamide. Journal of Ethnopharmacology. PMID 29042288 DOI: 10.1016/J.Jep.2017.10.012  0.56
2017 Kellogg JJ, Wallace ED, Graf TN, Oberlies NH, Cech NB. Conventional and accelerated-solvent extractions of green tea (camellia sinensis) for metabolomics-based chemometrics. Journal of Pharmaceutical and Biomedical Analysis. 145: 604-610. PMID 28787673 DOI: 10.1016/J.Jpba.2017.07.027  0.8
2017 Leyte-Lugo M, Britton ER, Foil DH, Brown AR, Todd DA, Rivera-Chávez J, Oberlies NH, Cech NB. Secondary Metabolites from the Leaves of the Medicinal Plant Goldenseal (Hydrastis canadensis). Phytochemistry Letters. 20: 54-60. PMID 28736584 DOI: 10.1016/J.Phytol.2017.03.012  0.8
2017 Todd DA, Parlet CP, Crosby HA, Malone CL, Heilmann KP, Horswill AR, Cech NB. Targeting quorum sensing signal biosynthesis to fight antibiotic resistant infections: Ambuic acid as a model inhibitor. Antimicrobial Agents and Chemotherapy. PMID 28607020 DOI: 10.1128/Aac.00263-17  0.56
2017 Kellogg JJ, Graf TN, Paine MF, McCune JS, Kvalheim OM, Oberlies NH, Cech NB. Comparison of Metabolomics Approaches for Evaluating the Variability of Complex Botanical Preparations: Green Tea (Camellia sinensis) as a Case Study. Journal of Natural Products. PMID 28453261 DOI: 10.1021/Acs.Jnatprod.6B01156  0.8
2016 Egan JM, Kaur A, Raja HA, Kellogg JJ, Oberlies NH, Cech NB. Antimicrobial fungal endophytes from the botanical medicine goldenseal (Hydrastis canadensis). Phytochemistry Letters. 17: 219-225. PMID 28603575 DOI: 10.1016/J.Phytol.2016.07.031  0.8
2016 Kaur A, Oberhofer M, Juzumaite M, Raja HA, Gulledge TV, Kao D, Faeth SH, Laster SM, Oberlies NH, Cech NB. Secondary Metabolites from Fungal Endophytes of Echinacea purpurea Suppress Cytokine Secretion by Macrophage-Type Cells. Natural Product Communications. 11: 1143-1146. PMID 28479944 DOI: 10.1177/1934578X1601100827  0.8
2016 Brooks WC, Paguigan ND, Raja HA, Moy FJ, Cech NB, Pearce CJ, Oberlies NH. qNMR for profiling the production of fungal secondary metabolites. Magnetic Resonance in Chemistry : Mrc. PMID 28024162 DOI: 10.1002/Mrc.4571  0.8
2016 Caesar LK, Cech NB. A Review of the Medicinal Uses and Pharmacology of Ashitaba. Planta Medica. PMID 27399234 DOI: 10.1055/S-0042-110496  0.68
2016 Todd DA, Zich DB, Ettefagh KA, Kavanaugh JS, Horswill AR, Cech NB. Hybrid Quadrupole-Orbitrap mass spectrometry for quantitative measurement of quorum sensing inhibition. Journal of Microbiological Methods. PMID 27237773 DOI: 10.1016/J.Mimet.2016.05.024  1
2016 Graf TN, Cech NB, Polyak SJ, Oberlies NH. A validated UHPLC-tandem mass spectrometry method for quantitative analysis of flavonolignans in milk thistle (Silybum marianum) extracts. Journal of Pharmaceutical and Biomedical Analysis. 126: 26-33. PMID 27136284 DOI: 10.1016/J.Jpba.2016.04.028  1
2016 Kellogg JJ, Todd DA, Egan JM, Raja HA, Oberlies NH, Kvalheim OM, Cech NB. Biochemometrics for Natural Products Research: Comparison of Data Analysis Approaches and Application to Identification of Bioactive Compounds. Journal of Natural Products. PMID 26841051 DOI: 10.1021/Acs.Jnatprod.5B01014  1
2016 Egan JM, Kaur A, Raja HA, Kellogg JJ, Oberlies NH, Cech NB. Antimicrobial fungal endophytes from the botanical medicine goldenseal (Hydrastis canadensis) Phytochemistry Letters. 17: 219-225. DOI: 10.1016/j.phytol.2016.07.031  1
2015 Britton ER, Ibberson CB, Horswill AR, Cech NB. A new mass spectrometry based bioassay for the direct assessment of hyaluronidase activity and inhibition. Journal of Microbiological Methods. 119: 163-167. PMID 26519769 DOI: 10.1016/J.Mimet.2015.10.019  1
2015 Jarmusch AK, Musso AM, Shymanovich T, Jarmusch SA, Weavil MJ, Lovin ME, Ehrmann BM, Saari S, Nichols DE, Faeth SH, Cech NB. Comparison of electrospray ionization and atmospheric pressure photoionization liquid chromatography mass spectrometry methods for analysis of ergot alkaloids from endophyte-infected sleepygrass (Achnatherum robustum). Journal of Pharmaceutical and Biomedical Analysis. 117: 11-17. PMID 26340558 DOI: 10.1016/J.Jpba.2015.08.031  1
2015 Raja HA, Kaur A, El-Elimat T, Figueroa M, Kumar R, Deep G, Agarwal R, Faeth SH, Cech NB, Oberlies NH. Phylogenetic and chemical diversity of fungal endophytes isolated from Silybum marianum (L) Gaertn. (milk thistle). Mycology. 6: 8-27. PMID 26000195 DOI: 10.1080/21501203.2015.1009186  1
2015 Brown AR, Ettefagh KA, Todd D, Cole PS, Egan JM, Foil DH, Graf TN, Schindler BD, Kaatz GW, Cech NB. A mass spectrometry-based assay for improved quantitative measurements of efflux pump inhibition. Plos One. 10: e0124814. PMID 25961825 DOI: 10.1371/Journal.Pone.0124814  0.4
2015 Todd DA, Gulledge TV, Britton ER, Oberhofer M, Leyte-Lugo M, Moody AN, Shymanovich T, Grubbs LF, Juzumaite M, Graf TN, Oberlies NH, Faeth SH, Laster SM, Cech NB. Ethanolic Echinacea purpurea Extracts Contain a Mixture of Cytokine-Suppressive and Cytokine-Inducing Compounds, Including Some That Originate from Endophytic Bacteria. Plos One. 10: e0124276. PMID 25933416 DOI: 10.1371/Journal.Pone.0124276  1
2015 Daly SM, Elmore BO, Kavanaugh JS, Triplett KD, Figueroa M, Raja HA, El-Elimat T, Crosby HA, Femling JK, Cech NB, Horswill AR, Oberlies NH, Hall PR. ω-Hydroxyemodin limits staphylococcus aureus quorum sensing-mediated pathogenesis and inflammation. Antimicrobial Agents and Chemotherapy. 59: 2223-35. PMID 25645827 DOI: 10.1128/Aac.04564-14  1
2015 Bussey RO, Kaur A, Todd DA, Egan JM, El-Elimat T, Graf TN, Raja HA, Oberlies NH, Cech NB. Comparison of the chemistry and diversity of endophytes isolated from wild-harvested and greenhouse-cultivated yerba mansa (Anemopsis californica). Phytochemistry Letters. 11: 202-208. PMID 25642298 DOI: 10.1016/J.Phytol.2014.12.013  1
2015 Shymanovich T, Saari S, Lovin ME, Jarmusch AK, Jarmusch SA, Musso AM, Charlton ND, Young CA, Cech NB, Faeth SH. Alkaloid variation among epichloid endophytes of sleepygrass (Achnatherum robustum) and consequences for resistance to insect herbivores. Journal of Chemical Ecology. 41: 93-104. PMID 25501262 DOI: 10.1007/S10886-014-0534-X  1
2015 Todd DA, Gulledge TV, Britton ER, Oberhofer M, Leyte-Lugo M, Moody AN, Shymanovich T, Grubbs LF, Juzumaite M, Graf TN, Oberlies NH, Faeth SH, Laster SM, Cech NB. Alkylamide content of an Echinacea purpurea extract, chloroform layer, and column fractions from the chloroform layer. Plos One. DOI: 10.1371/Journal.Pone.0124276.T001  0.8
2015 Todd DA, Gulledge TV, Britton ER, Oberhofer M, Leyte-Lugo M, Moody AN, Shymanovich T, Grubbs LF, Juzumaite M, Graf TN, Oberlies NH, Faeth SH, Laster SM, Cech NB. Echinacea purpurea plants grown from sterilized seeds. Plos One. DOI: 10.1371/Journal.Pone.0124276.G008  0.8
2015 Todd DA, Gulledge TV, Britton ER, Oberhofer M, Leyte-Lugo M, Moody AN, Shymanovich T, Grubbs LF, Juzumaite M, Graf TN, Oberlies NH, Faeth SH, Laster SM, Cech NB. Alkylamides from Echinacea purpurea. Plos One. DOI: 10.1371/Journal.Pone.0124276.G003  0.8
2015 Leyte-Lugo M, Foil D, Todd D, Britton E, Cech N. Alkaloids, flavanones and other compounds new to Goldenseal (Hydrastis canadensis) Planta Medica. 81. DOI: 10.1055/S-0035-1556497  0.4
2014 Alfaro CM, Uwakweh AO, Todd DA, Ehrmann BM, Cech NB. Investigations of analyte-specific response saturation and dynamic range limitations in atmospheric pressure ionization mass spectrometry. Analytical Chemistry. 86: 10639-45. PMID 25268329 DOI: 10.1021/Ac502984A  1
2014 Olson ME, Todd DA, Schaeffer CR, Paharik AE, Van Dyke MJ, Büttner H, Dunman PM, Rohde H, Cech NB, Fey PD, Horswill AR. Staphylococcus epidermidis agr quorum-sensing system: signal identification, cross talk, and importance in colonization. Journal of Bacteriology. 196: 3482-93. PMID 25070736 DOI: 10.1128/Jb.01882-14  1
2014 Wagoner KM, Lehmann T, Huestis DL, Ehrmann BM, Cech NB, Wasserberg G. Identification of morphological and chemical markers of dry- and wet-season conditions in female Anopheles gambiae mosquitoes. Parasites & Vectors. 7: 294. PMID 24970701 DOI: 10.1186/1756-3305-7-294  1
2014 Figueroa M, Jarmusch AK, Raja HA, El-Elimat T, Kavanaugh JS, Horswill AR, Cooks RG, Cech NB, Oberlies NH. Polyhydroxyanthraquinones as quorum sensing inhibitors from the guttates of Penicillium restrictum and their analysis by desorption electrospray ionization mass spectrometry. Journal of Natural Products. 77: 1351-8. PMID 24911880 DOI: 10.1021/Np5000704  1
2014 Bussey RO, Sy-Cordero AA, Figueroa M, Carter FS, Falkinham JO, Oberlies NH, Cech NB. Antimycobacterial furofuran lignans from the roots of Anemopsis californica. Planta Medica. 80: 498-501. PMID 24687738 DOI: 10.1055/S-0034-1368352  1
2014 El-Elimat T, Raja HA, Graf TN, Faeth SH, Cech NB, Oberlies NH. Flavonolignans from Aspergillus iizukae, a fungal endophyte of milk thistle (Silybum marianum). Journal of Natural Products. 77: 193-9. PMID 24456525 DOI: 10.1021/Np400955Q  1
2014 Roux A, Todd DA, Velázquez JV, Cech NB, Sonenshein AL. Cody-Mediated regulation of the staphylococcus aureus Agr System integrates nutritional and population density signals Journal of Bacteriology. 196: 1184-1196. PMID 24391052 DOI: 10.1128/Jb.00128-13  1
2013 Cech NB, Horswill AR. Small-molecule quorum quenchers to prevent Staphylococcus aureus infection. Future Microbiology. 8: 1511-4. PMID 24266350 DOI: 10.2217/Fmb.13.134  1
2013 El-Elimat T, Figueroa M, Ehrmann BM, Cech NB, Pearce CJ, Oberlies NH. High-resolution MS, MS/MS, and UV database of fungal secondary metabolites as a dereplication protocol for bioactive natural products. Journal of Natural Products. 76: 1709-16. PMID 23947912 DOI: 10.1021/Np4004307  1
2013 Vandermolen KM, Cech NB, Paine MF, Oberlies NH. Rapid Quantitation of Furanocoumarins and Flavonoids in Grapefruit Juice using Ultra-Performance Liquid Chromatography. Phytochemical Analysis : Pca. 24: 654-60. PMID 23780830 DOI: 10.1002/Pca.2449  1
2013 Junio HA, Todd DA, Ettefagh KA, Ehrmann BM, Kavanaugh JS, Horswill AR, Cech NB. Quantitative analysis of autoinducing peptide I (AIP-I) from Staphylococcus aureus cultures using ultrahigh performance liquid chromatography-high resolving power mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 930: 7-12. PMID 23703543 DOI: 10.1016/J.Jchromb.2013.04.019  1
2013 Bame JR, Graf TN, Junio HA, Bussey RO, Jarmusch SA, El-Elimat T, Falkinham JO, Oberlies NH, Cech RA, Cech NB. Sarothrin from Alkanna orientalis is an antimicrobial agent and efflux pump inhibitor. Planta Medica. 79: 327-9. PMID 23468310 DOI: 10.1055/S-0032-1328259  1
2013 Cech NB, Yu K. Mass spectrometry for natural products research: Challenges, pitfalls, and opportunities Lcgc North America. 31: 938-947.  1
2012 Cech NB, Junio HA, Ackermann LW, Kavanaugh JS, Horswill AR. Quorum quenching and antimicrobial activity of goldenseal (Hydrastis canadensis) against methicillin-resistant Staphylococcus aureus (MRSA). Planta Medica. 78: 1556-61. PMID 22814821 DOI: 10.1055/S-0032-1315042  1
2012 Wan C, Yuan T, Li L, Kandhi V, Cech NB, Xie M, Seeram NP. Maplexins, new α-glucosidase inhibitors from red maple (Acer rubrum) stems. Bioorganic & Medicinal Chemistry Letters. 22: 597-600. PMID 22079755 DOI: 10.1016/J.Bmcl.2011.10.073  1
2012 Cech NB, Enke CG. Selectivity in Electrospray Ionization Mass Spectrometry Electrospray and Maldi Mass Spectrometry: Fundamentals, Instrumentation, Practicalities, and Biological Applications: Second Edition. 49-73. DOI: 10.1002/9780470588901.ch2  1
2011 Yuan T, Wan C, González-Sarrías A, Kandhi V, Cech NB, Seeram NP. Phenolic glycosides from sugar maple (Acer saccharum) bark. Journal of Natural Products. 74: 2472-6. PMID 22032697 DOI: 10.1021/Np200678N  1
2011 Cecil CE, Davis JM, Cech NB, Laster SM. Inhibition of H1N1 influenza A virus growth and induction of inflammatory mediators by the isoquinoline alkaloid berberine and extracts of goldenseal (Hydrastis canadensis). International Immunopharmacology. 11: 1706-14. PMID 21683808 DOI: 10.1016/J.Intimp.2011.06.002  1
2011 Junio HA, Sy-Cordero AA, Ettefagh KA, Burns JT, Micko KT, Graf TN, Richter SJ, Cannon RE, Oberlies NH, Cech NB. Synergy-directed fractionation of botanical medicines: a case study with goldenseal (Hydrastis canadensis). Journal of Natural Products. 74: 1621-9. PMID 21661731 DOI: 10.1021/Np200336G  1
2011 Ettefagh KA, Burns JT, Junio HA, Kaatz GW, Cech NB. Goldenseal (Hydrastis canadensis L.) extracts synergistically enhance the antibacterial activity of berberine via efflux pump inhibition. Planta Medica. 77: 835-40. PMID 21157683 DOI: 10.1055/S-0030-1250606  1
2011 Cebrián-Torrejón G, Spelman K, Leblanc K, Muñoz-Durango K, Gutiérrez ST, Ferreira ME, de Arias AR, Figadère B, Maciuk AFA, Grellier P, Cech NB, Poupon E. The antiplasmodium effects of a traditional South American remedy: Zanthoxylum chiloperone var. Angustifolium against chloroquine resistant and chloroquine sensitive strains of Plasmodium falciparum Brazilian Journal of Pharmacognosy. 21: 652-661. DOI: 10.1590/S0102-695X2011005000104  1
2010 Cech NB, Kandhi V, Davis JM, Hamilton A, Eads D, Laster SM. Echinacea and its alkylamides: effects on the influenza A-induced secretion of cytokines, chemokines, and PGE₂ from RAW 264.7 macrophage-like cells. International Immunopharmacology. 10: 1268-78. PMID 20674883 DOI: 10.1016/J.Intimp.2010.07.009  1
2010 Bae SS, Ehrmann BM, Ettefagh KA, Cech NB. A validated liquid chromatography-electrospray ionization-mass spectrometry method for quantification of spilanthol in Spilanthes acmella (L.) Murr. Phytochemical Analysis : Pca. 21: 438-43. PMID 20310072 DOI: 10.1002/Pca.1215  1
2010 Benson JM, Pokorny AJ, Rhule A, Wenner CA, Kandhi V, Cech NB, Shepherd DM. Echinacea purpurea extracts modulate murine dendritic cell fate and function. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 48: 1170-7. PMID 20149833 DOI: 10.1016/J.Fct.2010.02.007  1
2009 Spelman K, Iiams-Hauser K, Cech NB, Taylor EW, Smirnoff N, Wenner CA. Role for PPARgamma in IL-2 inhibition in T cells by Echinacea-derived undeca-2E-ene-8,10-diynoic acid isobutylamide. International Immunopharmacology. 9: 1260-4. PMID 19712756 DOI: 10.1016/J.Intimp.2009.08.009  1
2009 Spelman K, Wetschler MH, Cech NB. Comparison of alkylamide yield in ethanolic extracts prepared from fresh versus dry Echinacea purpurea utilizing HPLC-ESI-MS. Journal of Pharmaceutical and Biomedical Analysis. 49: 1141-9. PMID 19321283 DOI: 10.1016/J.Jpba.2009.02.011  1
2008 Ehrmann BM, Henriksen T, Cech NB. Relative importance of basicity in the gas phase and in solution for determining selectivity in electrospray ionization mass spectrometry. Journal of the American Society For Mass Spectrometry. 19: 719-28. PMID 18325781 DOI: 10.1016/J.Jasms.2008.01.003  1
2007 Raner GM, Cornelious S, Moulick K, Wang Y, Mortenson A, Cech NB. Effects of herbal products and their constituents on human cytochrome P450(2E1) activity. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 45: 2359-65. PMID 17658211 DOI: 10.1016/J.Fct.2007.06.012  1
2007 Stiles EA, Cech NB, Dee SM, Lacey EP. Temperature-sensitive anthocyanin production in flowers of Plantago lanceolata Physiologia Plantarum. 129: 756-765. DOI: 10.1111/J.1399-3054.2007.00855.X  1
2006 Cech NB, Tutor K, Doty BA, Spelman K, Sasagawa M, Raner GM, Wenner CA. Liver enzyme-mediated oxidation of Echinacea purpurea alkylamides: production of novel metabolites and changes in immunomodulatory activity. Planta Medica. 72: 1372-7. PMID 17054047 DOI: 10.1055/S-2006-951718  1
2006 Sasagawa M, Cech NB, Gray DE, Elmer GW, Wenner CA. Echinacea alkylamides inhibit interleukin-2 production by Jurkat T cells. International Immunopharmacology. 6: 1214-21. PMID 16714226 DOI: 10.1016/J.Intimp.2006.02.003  1
2006 Cech NB, Eleazer MS, Shoffner LT, Crosswhite MR, Davis AC, Mortenson AM. High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts. Journal of Chromatography. A. 1103: 219-28. PMID 16298376 DOI: 10.1016/J.Chroma.2005.11.008  1
2005 Henriksen T, Juhler RK, Svensmark B, Cech NB. The relative influences of acidity and polarity on responsiveness of small organic molecules to analysis with negative ion electrospray ionization mass spectrometry (ESI-MS). Journal of the American Society For Mass Spectrometry. 16: 446-55. PMID 15792713 DOI: 10.1016/J.Jasms.2004.11.021  1
2002 Cunningham C, Glimer RL, Hash HD, Cech NB. ESI-MS for the identification and quantitation of bioactive alkaloids in the aerial portions of the endangered medicinal plant goldenseal (hydrastis canadensis L.) Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 377-378.  1
2001 Cech NB, Enke CG. Practical implications of some recent studies in electrospray ionization fundamentals. Mass Spectrometry Reviews. 20: 362-87. PMID 11997944 DOI: 10.1002/Mas.10008  1
2001 Cech NB, Enke CG. Effect of affinity for droplet surfaces on the fraction of analyte molecules charged during electrospray droplet fission. Analytical Chemistry. 73: 4632-9. PMID 11605841 DOI: 10.1021/Ac001267J  1
2001 Cech NB, Krone JR, Enke CG. Electrospray ionization detection of inherently nonresponsive epoxides by peptide binding. Rapid Communications in Mass Spectrometry : Rcm. 15: 1040-4. PMID 11404839 DOI: 10.1002/Rcm.337  1
2001 Cech NB, Krone JR, Enke CG. Predicting electrospray response from chromatographic retention time. Analytical Chemistry. 73: 208-13. PMID 11199967 DOI: 10.1021/Ac0006019  1
2000 Amad MH, Cech NB, Jackson GS, Enke CG. Importance of gas-phase proton affinities in determining the electrospray ionization response for analytes and solvents. Journal of Mass Spectrometry : Jms. 35: 784-9. PMID 10934432 DOI: 10.1002/1096-9888(200007)35:7<784::Aid-Jms17>3.0.Co;2-Q  1
2000 Cech NB, Enke CG. Relating electrospray ionization response to nonpolar character of small peptides. Analytical Chemistry. 72: 2717-23. PMID 10905298 DOI: 10.1021/Ac9914869  1
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