Romas J. Kazlauskas - Publications

Biochemistry, Molecular Biology, and Biophysics University of Minnesota, Twin Cities, Minneapolis, MN 
Stereoselective Enzymatic Reactions.

127 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Lin H, Kazlauskas RJ, Travisano M. Developmental evolution facilitates rapid adaptation. Scientific Reports. 7: 15891. PMID 29162942 DOI: 10.1038/s41598-017-16229-0  1
2017 Lee PG, Kim J, Kim EJ, Lee SH, Choi KY, Kazlauskas RJ, Kim BG. Biosynthesis of (-)-5-hydroxy-equol and 5-hydroxy-dehydroequol from soy isoflavone, genistein using microbial whole cell bioconversion. Acs Chemical Biology. PMID 28985044 DOI: 10.1021/acschembio.7b00624  0.36
2017 Lee HR, Kazlauskas RJ, Park TH. One-step pretreatment of yellow poplar biomass using peracetic acid to enhance enzymatic digestibility. Scientific Reports. 7: 12216. PMID 28939889 DOI: 10.1038/s41598-017-12542-w  0.32
2016 Lin H, Travisano M, Kazlauskas RJ. The Fungus Trichoderma Regulates Submerged Conidiation Using the Steroid Pregnenolone. Acs Chemical Biology. PMID 27413801 DOI: 10.1021/acschembio.6b00376  1
2016 Lin H, Travisano M, Kazlauskas RJ. Experimental Evolution of Trichoderma citrinoviride for Faster Deconstruction of Cellulose. Plos One. 11: e0147024. PMID 26820897 DOI: 10.1371/journal.pone.0147024  1
2016 Devamani T, Rauwerdink AM, Lunzer M, Jones BJ, Mooney JL, Tan MA, Zhang ZJ, Xu JH, Dean AM, Kazlauskas RJ. Catalytic promiscuity of ancestral esterases and hydroxynitrile lyases. Journal of the American Chemical Society. PMID 26736133 DOI: 10.1021/jacs.5b12209  1
2015 Jung DH, Kim EJ, Jung E, Kazlauskas RJ, Choi KY, Kim BG. Production of p-hydroxybenzoic acid from p-coumaric acid by Burkholderia glumae BGR1. Biotechnology and Bioengineering. PMID 26693833 DOI: 10.1002/bit.25908  1
2015 Rauwerdink A, Lunzer M, Devamani T, Jones B, Mooney J, Zhang ZJ, Xu JH, Kazlauskas RJ, Dean AM. Evolution of a Catalytic Mechanism. Molecular Biology and Evolution. PMID 26681154 DOI: 10.1093/molbev/msv338  1
2015 Huang J, Jones BJ, Kazlauskas RJ. Stabilization of an α/β-Hydrolase by Introducing Proline Residues: Salicylic Acid Binding Protein 2 from Tobacco. Biochemistry. 54: 4330-41. PMID 26110207 DOI: 10.1021/acs.biochem.5b00333  1
2015 Rauwerdink A, Kazlauskas RJ. How the Same Core Catalytic Machinery Catalyzes 17 Different Reactions: The Serine-Histidine-Aspartate Catalytic Triad of α/β-Hydrolase Fold Enzymes Acs Catalysis. 5: 6153-6176. DOI: 10.1021/acscatal.5b01539  1
2014 Nedrud DM, Lin H, Lopez G, Padhi SK, Legatt GA, Kaz-Lauskas RJ. Uncovering divergent evolution of α/β-hydrolases: a surprising residue substitution needed to convert Hevea brasiliensis hydroxynitrile lyase into an esterase. Chemical Science (Royal Society of Chemistry : 2010). 5: 4265-4277. PMID 25346843 DOI: 10.1039/c4sc01544d  1
2014 von Langermann J, Nedrud DM, Kazlauskas RJ. Increasing the reaction rate of hydroxynitrile lyase from Hevea brasiliensis toward mandelonitrile by copying active site residues from an esterase that accepts aromatic esters. Chembiochem : a European Journal of Chemical Biology. 15: 1931-8. PMID 25044660 DOI: 10.1002/cbic.201402081  1
2014 Eum H, Kazlauskas RJ, Ha HJ. Molecular basis for the enantio- and diastereoselectivity of burkholderia cepacia lipase toward γ-Butyrolactone primary alcohols Iubmb Life. 356: 3585-3599. DOI: 10.1002/adsc.201400510  1
2013 Choi KY, Jung EO, Yun H, Yang YH, Kazlauskas RJ, Kim BG. Development of colorimetric HTS assay of cytochrome p450 for ortho-specific hydroxylation, and engineering of CYP102D1 with enhanced catalytic activity and regioselectivity. Chembiochem : a European Journal of Chemical Biology. 14: 1231-8. PMID 23780920 DOI: 10.1002/cbic.201300212  1
2013 Yin DT, Purpero VM, Fujii R, Jing Q, Kazlauskas RJ. New structural motif for carboxylic acid perhydrolases. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 3037-46. PMID 23325572 DOI: 10.1002/chem.201202027  1
2013 Jung DH, Choi W, Choi KY, Jung E, Yun H, Kazlauskas RJ, Kim BG. Bioconversion of p-coumaric acid to p-hydroxystyrene using phenolic acid decarboxylase from B. amyloliquefaciens in biphasic reaction system. Applied Microbiology and Biotechnology. 97: 1501-11. PMID 23081771 DOI: 10.1007/s00253-012-4358-8  1
2012 Yin DT, Kazlauskas RJ. Revised molecular basis of the promiscuous carboxylic acid perhydrolase activity in serine hydrolases. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 8130-9. PMID 22618813 DOI: 10.1002/chem.201200052  1
2012 Bornscheuer UT, Huisman GW, Kazlauskas RJ, Lutz S, Moore JC, Robins K. Engineering the third wave of biocatalysis. Nature. 485: 185-94. PMID 22575958 DOI: 10.1038/nature11117  1
2012 Choi KY, Jung E, Jung DH, Pandey BP, Yun H, Park HY, Kazlauskas RJ, Kim BG. Cloning, expression and characterization of CYP102D1, a self-sufficient P450 monooxygenase from Streptomyces avermitilis. The Febs Journal. 279: 1650-62. PMID 22188665 DOI: 10.1111/j.1742-4658.2011.08462.x  1
2012 Malla S, Koffas MA, Kazlauskas RJ, Kim BG. Production of 7-O-methyl aromadendrin, a medicinally valuable flavonoid, in Escherichia coli. Applied and Environmental Microbiology. 78: 684-94. PMID 22101053 DOI: 10.1128/AEM.06274-11  1
2012 Kazlauskas R. Biology evolves to fight chemistry Chemistry and Biology. 19: 435-437. DOI: 10.1016/j.chembiol.2012.04.004  1
2012 Kazlauskas RJ, Bornscheuer UT. 7.22 Enzyme Catalytic Promiscuity: Expanding the Catalytic Action of Enzymes to New Reactions Comprehensive Chirality. 7: 465-480. DOI: 10.1016/B978-0-08-095167-6.00729-1  1
2012 Bornscheuer UT, Kazlauskas RJ. Enzymatic Catalytic Promiscuity and the Design of New Enzyme Catalyzed Reactions Enzyme Catalysis in Organic Synthesis, Third Edition. 3: 1695-1733. DOI: 10.1002/9783527639861.ch41  1
2011 Bornscheuer U, Kazlauskas RJ. Survey of protein engineering strategies. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit26.7. PMID 22045562 DOI: 10.1002/0471140864.ps2607s66  1
2011 Chen GQ, Kazlauskas R. Chemical biotechnology in progress Current Opinion in Biotechnology. 22: 747-748. PMID 21862309 DOI: 10.1016/j.copbio.2011.08.003  1
2011 Jochens H, Hesseler M, Stiba K, Padhi SK, Kazlauskas RJ, Bornscheuer UT. Protein engineering of α/β-hydrolase fold enzymes. Chembiochem : a European Journal of Chemical Biology. 12: 1508-17. PMID 21506229 DOI: 10.1002/cbic.201000771  1
2011 Jiang Y, Morley KL, Schrag JD, Kazlauskas RJ. Different active-site loop orientation in serine hydrolases versus acyltransferases. Chembiochem : a European Journal of Chemical Biology. 12: 768-76. PMID 21351219 DOI: 10.1002/cbic.201000693  1
2011 Yin DT, Jing Q, AlDajani WW, Duncan S, Tschirner U, Schilling J, Kazlauskas RJ. Improved pretreatment of lignocellulosic biomass using enzymatically-generated peracetic acid. Bioresource Technology. 102: 5183-92. PMID 21345668 DOI: 10.1016/j.biortech.2011.01.079  1
2011 Colton IJ, Yin D, Grochulski P, Kazlauskas RJ. Molecular basis of chiral acid recognition by Candida rugosa lipase: X-ray structure of transition state analog and modeling of the hydrolysis of methyl 2-methoxy-2-phenylacetate Advanced Synthesis and Catalysis. 353: 2529-2544. DOI: 10.1002/adsc.201100459  1
2011 Kazlauskas R. Engineering Enantioselectivity in Enzyme-Catalyzed Reactions Protein Engineering Handbook, Volume 1 & Volume 2. 1: 15-46. DOI: 10.1002/9783527634026.ch2  1
2011 Kazlauskas RJ, Kim BG. Biotechnology Tools for Green Synthesis: Enzymes, Metabolic Pathways, and their Improvement by Engineering Biocatalysis For Green Chemistry and Chemical Process Development. 1-22. DOI: 10.1002/9781118028308.ch1  1
2011 Tao J, Kazlauskas R. Biocatalysis for Green Chemistry and Chemical Process Development Biocatalysis For Green Chemistry and Chemical Process Development. DOI: 10.1002/9781118028308  1
2010 Padhi SK, Fujii R, Legatt GA, Fossum SL, Berchtold R, Kazlauskas RJ. Switching from an esterase to a hydroxynitrile lyase mechanism requires only two amino acid substitutions. Chemistry & Biology. 17: 863-71. PMID 20797615 DOI: 10.1016/j.chembiol.2010.06.013  1
2010 Yin de LT, Bernhardt P, Morley KL, Jiang Y, Cheeseman JD, Purpero V, Schrag JD, Kazlauskas RJ. Switching catalysis from hydrolysis to perhydrolysis in Pseudomonas fluorescens esterase. Biochemistry. 49: 1931-42. PMID 20112920 DOI: 10.1021/bi9021268  1
2010 Duncan S, Jing Q, Katona A, Kazlauskas RJ, Schilling J, Tschirner U, Aldajani WW. Increased saccharification yields from aspen biomass upon treatment with enzymatically generated peracetic acid. Applied Biochemistry and Biotechnology. 160: 1637-52. PMID 19484411 DOI: 10.1007/s12010-009-8639-3  1
2010 Gorke JT, Srienc F, Kazlauskas RJ. Deep eutectic solvents for Candida antarctica lipase B-catalyzed reactions Acs Symposium Series. 1038: 169-180. DOI: 10.1021/bk-2010-1038.ch014  1
2010 Gorke J, Srienc F, Kazlauskas R. Toward advanced ionic liquids. Polar, enzyme-friendly solvents for biocatalysis Biotechnology and Bioprocess Engineering. 15: 40-53. DOI: 10.1007/s12257-009-3079-z  1
2010 Jing Q, Kazlauskas RJ. Regioselective Hydroformylation of Styrene Using Rhodium-Substituted Carbonic Anhydrase Chemcatchem. 2: 953-957. DOI: 10.1002/cctc.201000159  1
2009 Park JH, Ha HJ, Lee WK, Généreux-Vincent T, Kazlauskas RJ. Molecular basis for the stereoselective ammoniolysis of N-alkyl aziridine-2-carboxylates catalyzed by Candida antarctica lipase B. Chembiochem : a European Journal of Chemical Biology. 10: 2213-22. PMID 19672908 DOI: 10.1002/cbic.200900343  1
2009 Kazlauskas RJ, Bornscheuer UT. Finding better protein engineering strategies. Nature Chemical Biology. 5: 526-9. PMID 19620988 DOI: 10.1038/nchembio0809-526  1
2009 Jochens H, Stiba K, Savile C, Fujii R, Yu JG, Gerassenkov T, Kazlauskas RJ, Bornscheuer UT. Converting an esterase into an epoxide hydrolase. Angewandte Chemie (International Ed. in English). 48: 3532-5. PMID 19350592 DOI: 10.1002/anie.200806276  0.56
2009 Kazlauskas R, Lutz S. Engineering enzymes by 'intelligent' design. Current Opinion in Chemical Biology. 13: 1-2. PMID 19272831 DOI: 10.1016/j.cbpa.2009.02.022  1
2009 Jing Q, Okrasa K, Kazlauskas RJ. Stereoselective hydrogenation of olefins using rhodium-substituted carbonic anhydrase--a new reductase. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 1370-6. PMID 19115310 DOI: 10.1002/chem.200801673  1
2009 Jing Q, Okrasa K, Kazlauskas RJ. Manganese-substituted α-carbonic anhydrase as an enantioselective peroxidase Topics in Organometallic Chemistry. 25: 45-61. DOI: 10.1007/978-3-540-87757-8_3  1
2009 Gadler P, Faber K, Savile CK, Kazlauskas RJ, Carnell AJ, Breen G. Kinetic Resolutions Using Biotransformations Practical Methods For Biocatalysis and Biotransformations. 117-131. DOI: 10.1002/9780470748589.ch3  1
2008 Mugford PF, Wagner UG, Jiang Y, Faber K, Kazlauskas RJ. Enantiocomplementary enzymes: classification, molecular basis for their enantiopreference, and prospects for mirror-image biotransformations. Angewandte Chemie (International Ed. in English). 47: 8782-93. PMID 18850616 DOI: 10.1002/anie.200705159  1
2008 Gorke JT, Srienc F, Kazlauskas RJ. Hydrolase-catalyzed biotransformations in deep eutectic solvents. Chemical Communications (Cambridge, England). 1235-7. PMID 18309428 DOI: 10.1039/b716317g  1
2008 Jing Q, Kazlauskas RJ. Determination of absolute configuration of secondary alcohols using lipase-catalyzed kinetic resolutions. Chirality. 20: 724-35. PMID 18278808 DOI: 10.1002/chir.20543  1
2008 Kazlauskas RJ, Bornscheuer UT. Biotransformations with Lipases Biotechnology: Second, Completely Revised Edition. 8: 36-191. DOI: 10.1002/9783527620906.ch3  1
2008 Gorke JT, Srienc F, Kazlauskas RJ. Deep eutectic solvents: Inexpensive, biologically-derived media for enzyme catalysis Aiche Annual Meeting, Conference Proceedings 1
2007 Gorke JT, Okrasa K, Louwagie A, Kazlauskas RJ, Srienc F. Enzymatic synthesis of poly(hydroxyalkanoates) in ionic liquids. Journal of Biotechnology. 132: 306-13. PMID 17543408 DOI: 10.1016/j.jbiotec.2007.04.001  1
2006 Kazlauskas RJ. Engineering a multipurpose catalyst. Nature Chemical Biology. 2: 514-5. PMID 16983384 DOI: 10.1038/nchembio1006-514  1
2006 Lavandera I, Fernández S, Magdalena J, Ferrero M, Grewal H, Savile CK, Kazlauskas RJ, Gotor V. Remote interactions explain the unusual regioselectivity of lipase from Pseudomonas cepacia toward the secondary hydroxyl of 2'-deoxynucleosides. Chembiochem : a European Journal of Chemical Biology. 7: 693-8. PMID 16491501 DOI: 10.1002/cbic.200500451  1
2006 Okrasa K, Kazlauskas RJ. Manganese-substituted carbonic anhydrase as a new peroxidase. Chemistry (Weinheim An Der Bergstrasse, Germany). 12: 1587-96. PMID 16416502 DOI: 10.1002/chem.200501413  1
2006 Nisole A, Lussier FX, Morley KL, Shareck F, Kazlauskas RJ, Dupont C, Pelletier JN. Extracellular production of Streptomyces lividans acetyl xylan esterase A in Escherichia coli for rapid detection of activity. Protein Expression and Purification. 46: 274-84. PMID 16256365 DOI: 10.1016/j.pep.2005.09.008  1
2006 Anastas P, Kazlauskas R, Sheldrake G. Ten years of green chemistry at the Gordon Research Conferences: Frontiers of science Green Chemistry. 8: 677-678. DOI: 10.1039/b608918f  1
2006 Morley KL, Chauve G, Kazlauskas R, Dupont C, Shareck F, Marchessault RH. Acetyl xylan esterase-catalyzed deacetylation of chitin and chitosan Carbohydrate Polymers. 63: 310-315. DOI: 10.1016/j.carbpol.2005.07.034  1
2006 Savile CK, Kazlauskas RJ. The 3-(3-pyridine)propionyl anchor group for protease-catalyzed resolutions: p-toluenesulfinamide and sterically hindered secondary alcohols Advanced Synthesis and Catalysis. 348: 1183-1192. DOI: 10.1002/adsc.200606040  1
2006 Kazlauskas RJ. Quantitative Assay of Hydrolases for Activity and Selectivity Using Color Changes Enzyme Assays: High-Throughput Screening, Genetic Selection and Fingerprinting. 15-39. DOI: 10.1002/3527607846.ch1  1
2006 Bornscheuer UT, Kazlauskas RJ. Hydrolases in Organic Synthesis: Regio- and Stereoselective Biotransformations: Second Edition Hydrolases in Organic Synthesis: Regio- and Stereoselective Biotransformations: Second Edition. 1-355. DOI: 10.1002/3527607544  1
2005 Savile CK, Kazlauskas RJ. How substrate solvation contributes to the enantioselectivity of subtilisin toward secondary alcohols. Journal of the American Chemical Society. 127: 12228-9. PMID 16131193 DOI: 10.1021/ja0528937  1
2005 Kazlauskas R. Biological chemistry: Enzymes in focus Nature. 436: 1096-1097. PMID 16121163 DOI: 10.1038/4361096a  1
2005 Lavandera I, Fernández S, Magdalena J, Ferrero M, Kazlauskas RJ, Gotor V. An inverse substrate orientation for the regioselective acylation of 3',5'-diaminonucleosides catalyzed by Candida antarctica lipase B? Chembiochem : a European Journal of Chemical Biology. 6: 1381-90. PMID 15977272 DOI: 10.1002/cbic.200400422  1
2005 Mugford PF, Magloire VP, Kazlauskas RJ. Unexpected subtilisin-catalyzed hydrolysis of a sulfinamide bond in preference to a carboxamide bond in N-acyl sulfinamides. Journal of the American Chemical Society. 127: 6536-7. PMID 15869266 DOI: 10.1021/ja0506105  1
2005 Morley KL, Kazlauskas RJ. Improving enzyme properties: when are closer mutations better? Trends in Biotechnology. 23: 231-7. PMID 15866000 DOI: 10.1016/j.tibtech.2005.03.005  1
2005 Mezzetti A, Schrag JD, Cheong CS, Kazlauskas RJ. Mirror-image packing in enantiomer discrimination molecular basis for the enantioselectivity of B.cepacia lipase toward 2-methyl-3-phenyl-1-propanol. Chemistry & Biology. 12: 427-37. PMID 15850979 DOI: 10.1016/j.chembiol.2005.01.016  1
2005 Kazlauskas RJ. Enhancing catalytic promiscuity for biocatalysis. Current Opinion in Chemical Biology. 9: 195-201. PMID 15811805 DOI: 10.1016/j.cbpa.2005.02.008  1
2005 Bernhardt P, Hult K, Kazlauskas RJ. Molecular basis of perhydrolase activity in serine hydrolases. Angewandte Chemie (International Ed. in English). 44: 2742-6. PMID 15803517 DOI: 10.1002/anie.200463006  1
2005 Savile CK, Magloire VP, Kazlauskas RJ. Subtilisin-catalyzed resolution of N-acyl arylsulfinamides. Journal of the American Chemical Society. 127: 2104-13. PMID 15713087 DOI: 10.1021/ja045397b  1
2005 Park S, Morley KL, Horsman GP, Holmquist M, Hult K, Kazlauskas RJ. Focusing mutations into the P. fluorescens esterase binding site increases enantioselectivity more effectively than distant mutations. Chemistry & Biology. 12: 45-54. PMID 15664514 DOI: 10.1016/j.chembiol.2004.10.012  1
2005 Cheeseman JD, Corbett AD, Gleason JL, Kazlauskas RJ. Receptor-assisted combinatorial chemistry: thermodynamics and kinetics in drug discovery. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 1708-16. PMID 15565741 DOI: 10.1002/chem.200400371  1
2004 Bornscheuer UT, Kazlauskas RJ. Catalytic promiscuity in biocatalysis: using old enzymes to form new bonds and follow new pathways. Angewandte Chemie (International Ed. in English). 43: 6032-40. PMID 15523680 DOI: 10.1002/anie.200460416  1
2004 Mugford PF, Lait SM, Keay BA, Kazlauskas RJ. Enantiocomplementary enzymatic resolution of the chiral auxiliary: cis,cis-6-(2,2-dimethylpropanamido)spiro[4.4]nonan-1-ol and the molecular basis for the high enantioselectivity of subtilisin Carlsberg. Chembiochem : a European Journal of Chemical Biology. 5: 980-7. PMID 15239056 DOI: 10.1002/cbic.200300909  1
2004 Cheeseman JD, Tocilj A, Park S, Schrag JD, Kazlauskas RJ. Structure of an aryl esterase from Pseudomonas fluorescens. Acta Crystallographica. Section D, Biological Crystallography. 60: 1237-43. PMID 15213385 DOI: 10.1107/S0907444904010522  1
2004 Corbett AD, Cheeseman JD, Kazlauskas RJ, Gleason JL. Pseudodynamic combinatorial libraries: a receptor-assisted approach for drug discovery. Angewandte Chemie (International Ed. in English). 43: 2432-6. PMID 15114583 DOI: 10.1002/anie.200453769  1
2004 Kazlauskas R. Integrating biocatalysis into organic synthesis Tetrahedron Asymmetry. 15: 2727-2728. DOI: 10.1016/j.tetasy.2004.08.001  1
2004 Morley KL, Magloire VP, Guérard C, Kazlauskas RJ. Parallel synthesis of an ester library for substrate mapping of esterases and lipases Tetrahedron Asymmetry. 15: 3005-3009. DOI: 10.1016/j.tetasy.2004.07.048  1
2004 Somers NA, Kazlauskas RJ. Mapping the substrate selectivity and enantioselectivity of esterases from thermophiles Tetrahedron Asymmetry. 15: 2991-3004. DOI: 10.1016/j.tetasy.2004.07.044  1
2003 Park S, Kazlauskas RJ. Biocatalysis in ionic liquids - advantages beyond green technology. Current Opinion in Biotechnology. 14: 432-7. PMID 12943854 DOI: 10.1016/S0958-1669(03)00100-9  1
2003 Horsman GP, Liu AM, Henke E, Bornscheuer UT, Kazlauskas RJ. Mutations in distant residues moderately increase the enantioselectivity of Pseudomonas fluorescens esterase towards methyl 3bromo-2-methylpropanoate and ethyl 3phenylbutyrate. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 1933-9. PMID 12740839 DOI: 10.1002/chem.200204551  1
2003 Park S, Viklund F, Hult K, Kazlauskas RJ. Vacuum-driven lipase-catalysed direct condensation of L-ascorbic acid and fatty acids in ionic liquids: Synthesis of a natural surface active antioxidant Green Chemistry. 5: 715-719. DOI: 10.1039/b307715b  1
2003 Mezzetti A, Keith C, Kazlauskas RJ. Highly enantioselective kinetic resolution of primary alcohols of the type Ph-X-CH(CH3)-CH2OH by Pseudomonas cepacia lipase: Effect of acyl chain length and solvent Tetrahedron Asymmetry. 14: 3917-3924. DOI: 10.1016/j.tetasy.2003.09.049  1
2003 Park S, Forró E, Grewal H, Fülöp F, Kazlauskas RJ. Molecular Basis for the Enantioselective Ring Opening of β-Lactams Catalyzed by Candida antarctica Lipase B Advanced Synthesis and Catalysis. 345: 986-995. DOI: 10.1002/adsc.200303069  1
2003 Park S, Viklund F, Huit K, Kazlauskas RJ. Ionic liquids create new opportunities for nonaqueous biocatalysis with polar substrates: Acylation of glucose and ascorbic acid Acs Symposium Series. 856: 225-238.  1
2002 Cheeseman JD, Corbett AD, Shu R, Croteau J, Gleason JL, Kazlauskas RJ. Amplification of screening sensitivity through selective destruction: theory and screening of a library of carbonic anhydrase inhibitors. Journal of the American Chemical Society. 124: 5692-701. PMID 12010042 DOI: 10.1021/ja017099+  1
2002 Kazlauskas R. Conference report of the 5th Japanese Symposium on the Chemistry of Biocatalysis, 13-14 December 2001, Okayama, Japan Journal of Molecular Catalysis - B Enzymatic. 17: 267. DOI: 10.1016/S1381-1177(02)00045-0  1
2001 Park S, Kazlauskas RJ. Improved preparation and use of room-temperature ionic liquids in lipase-catalyzed enantio- and regioselective acylations. The Journal of Organic Chemistry. 66: 8395-401. PMID 11735517 DOI: 10.1021/jo015761e  1
2001 Kazlauskas R. Modeling - A tool for experimentalists Science. 293: 2277-2279. PMID 11567144 DOI: 10.1126/science.293.5538.2277  1
2001 Gascoyne DG, Finkbeiner HL, Chan KP, Gordon JL, Stewart KR, Kazlauskas RJ. Molecular basis for enantioselectivity of lipase from Chromobacterium viscosum toward the diesters of 2,3-dihydro-3-(4'-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-ol. The Journal of Organic Chemistry. 66: 3041-8. PMID 11325269 DOI: 10.1021/jo005681v  1
2001 Liu AMF, Somers NA, Kazlauskas RJ, Brush TS, Zocher F, Enzelberger MM, Bornscheuer UT, Horsman GP, Mezzetti A, Schmidt-Dannert C, Schmid RD. Mapping the substrate selectivity of new hydrolases using colorimetric screening: Lipases from Bacillus thermocatenulatus and Ophiostoma piliferum, esterases from Pseudomonas fluorescens and Streptomyces diastatochromogenes Tetrahedron Asymmetry. 12: 545-556. DOI: 10.1016/S0957-4166(01)00072-6  1
2000 Kazlauskas RJ. Molecular modeling and biocatalysis: explanations, predictions, limitations, and opportunities. Current Opinion in Chemical Biology. 4: 81-8. PMID 10679382 DOI: 10.1016/S1367-5931(99)00056-3  1
1999 Tuomi WV, Kazlauskas RJ. Molecular Basis for Enantioselectivity of Lipase from Pseudomonas cepacia toward Primary Alcohols. Modeling, Kinetics, and Chemical Modification of Tyr29 to Increase or Decrease Enantioselectivity. The Journal of Organic Chemistry. 64: 2638-2647. PMID 11674331 DOI: 10.1021/jo981783y  1
1999 Zhang M, Kazlauskas R. First preparation of enantiopure indane monomer, (S)-(-)- and (R)-(+)- 2,3-dihydro-3-(4'-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-ol, via a unique enantio- and regioselective enzymatic kinetic resolution Journal of Organic Chemistry. 64: 7498-7503. DOI: 10.1021/jo990795w  1
1999 Janes LE, Cimpoia A, Kazlauskas RJ. Protease-mediated separation of cis and trans diastereomers of 2(R,S)- benzyloxymethyl-4(S)-carboxylic acid 1,3-dioxolane methyl ester: Intermediates for the synthesis of dioxolane nucleosides Journal of Organic Chemistry. 64: 9019-9029. DOI: 10.1021/jo990757c  1
1999 Weber HK, Weber H, Kazlauskas RJ. 'Watching' lipase-catalyzed acylations using 1H NMR: Competing hydrolysis of vinyl acetate in dry organic solvents Tetrahedron Asymmetry. 10: 2635-2638. DOI: 10.1016/S0957-4166(99)00274-8  1
1998 Kazlauskas RJ, Weber HK. Improving hydrolases for organic synthesis. Current Opinion in Chemical Biology. 2: 121-6. PMID 9667912  1
1998 Janes LE, Löwendahl AC, Kazlauskas RJ. Quantitative screening of hydrolase libraries using pH indicators: Identifying active and enantioselective hydrolases Chemistry - a European Journal. 4: 2324-2331. DOI: 10.1002/(SICI)1521-3765(19981102)4:11<2324::AID-CHEM2324>3.0.CO;2-I  1
1997 Kazlauskas RJ, Weissfloch ANE. A structure-based rationalization of the enantiopreference of subtilisin toward secondary alcohols and isosteric primary amines Journal of Molecular Catalysis - B Enzymatic. 3: 65-72. DOI: 10.1016/S1381-1177(96)00040-9  1
1997 Janes LE, Kazlauskas RJ. Quick E. A Fast Spectrophotometric Method to Measure the Enantioselectivity of Hydrolases Journal of Organic Chemistry. 62: 4560-4561.  1
1997 Janes LE, Kazlauskas RJ. Empirical rules for the enantiopreference of lipase from Aspergillus niger toward secondary alcohols and carboxylic acids, especially α-amino acids Tetrahedron Asymmetry. 8: 3719-3733.  1
1996 Nobes GAR, Kazlauskas RJ, Marchessault RH. Lipase-catalyzed ring-opening polymerization of lactones: a novel route to poly(hydroxyalkanoate)s Macromolecules. 29: 4829-4833. DOI: 10.1021/ma951774g  1
1995 Weissfloch ANE, Kazlauskas RJ. Enantiopreference of lipase from Pseudomonas cepacia toward primary alcohols Journal of Organic Chemistry. 60: 6959-6969.  1
1995 Colton IJ, Ahmed SN, Kazlauskas RJ. A 2-propanol treatment increases the enantioselectivity of Candida rugosa lipase toward esters of chiral carboxylic acids The Journal of Organic Chemistry. 60: 212-217.  1
1994 Kazlauskas RJ. Elucidating structure-mechanism relationships in lipases: prospects for predicting and engineering catalytic properties. Trends in Biotechnology. 12: 464-72. PMID 7765546 DOI: 10.1016/0167-7799(94)90022-1  1
1994 Ahmed SN, Kazlauskas RJ, Morinville AH, Grochulski P, Schrag JD, Cygler M. Enantioselectivity of candida rugosa lipase toward carboxylic acids: A predictive rule from substrate mapping and x-ray crystallography Biocatalysis and Biotransformation. 9: 209-225. DOI: 10.3109/10242429408992121  1
1994 Caron G, Tseng GWM, Kazlauskas RJ. Kinetic resolutions concentrate the minor enantiomer and aid measurement of high enantiomeric purity. Tetrahedron: Asymmetry. 5: 83-92. DOI: 10.1016/S0957-4166(00)80487-5  1
1994 Caron G, Kazlauskas RJ. Isolation of racemic 2,4-pentanediol and 2,5-hexanediol from commercial mixtures of racemic and meso isomers by way of cyclic sulfites. Tetrahedron: Asymmetry. 5: 657-664. DOI: 10.1016/0957-4166(94)80028-6  1
1994 Colton IJ, Kazlauskas RJ. Dicarboxylic acids link proton transfer across a liquid membrane to the synthesis of acyl phosphates. A model for P-type H+-ATPases Journal of Organic Chemistry. 59: 3626-3635.  1
1994 Serreqi AN, Kazlauskas RJ. Kinetic resolution of phosphines and phosphine oxides with phosphorus stereocenters by hydrolases Journal of Organic Chemistry. 59: 7609-7615.  1
1994 Ng-Youn-Chen MC, Serreqi AN, Huang Q, Kazlauskas RJ. Kinetic resolution of pipecolic acid using partially-purified lipase from Aspergillus niger Journal of Organic Chemistry. 59: 2075-2081.  1
1994 Cygler M, Grochulski P, Kazlauskas RJ, Schrag JD, Bouthillier F, Rubin B, Serreqi AN, Gupta AK. A structural basis for the chiral preferences of lipases Journal of the American Chemical Society. 116: 3180-3186.  1
1993 Kazlauskas RJ. Biocatalysis--becoming more predictable and selective. Trends in Biotechnology. 11: 439-40. PMID 7764396 DOI: 10.1016/0167-7799(93)90075-K  1
1993 Caron G, Kazlauskas RJ. Sequential kinetic resolution of (±)-2,3-butanediol in organic solvent using lipase from Pseudomonas cepacia. Tetrahedron: Asymmetry. 4: 1995-2000. DOI: 10.1016/S0957-4166(00)82248-X  1
1993 Gupta AK, Kazlauskas RJ. Substrate modification to increase the enantioselectivity of hydrolases. A route to optically-active cyclic allylic alcohols. Tetrahedron: Asymmetry. 4: 879-888. DOI: 10.1016/S0957-4166(00)80126-3  1
1992 Gupta AK, Kazlauskas RJ. Calibration plots to aid determination of high enantiomeric purity using chiral lanthanide shift reagents. Tetrahedron: Asymmetry. 3: 243-246. DOI: 10.1016/S0957-4166(00)80201-3  1
1992 Colton IJ, Kazlauskas RJ. Synthesis of an acylphosphate driven by a proton gradient. A model for H+-ATPase Journal of Organic Chemistry. 57: 7005-7006.  1
1991 Kazlauskas RJ, Weissfloch ANE, Rappaport AT, Cuccia LA. A rule to predict which enantiomer of a secondary alcohol reacts faster in reactions catalyzed by cholesterol esterase, lipase from Pseudomonas cepacia, and lipase from Candida rugosa Journal of Organic Chemistry. 56: 2656-2665.  1
1991 Caron G, Kazlauskas RJ. An optimized sequential kinetic resolution of trans-1,2-cyclohexanediol Journal of Organic Chemistry. 56: 7251-7256.  1
1989 Kazlauskas RJ. Resolution of binaphthols and spirobiindanols using cholesterol esterase Journal of the American Chemical Society. 111: 4953-4959.  1
1988 Kazlauskas RJ. Changing coenzymes improves oxidations catalyzed by alcohol dehydrogenase Journal of Organic Chemistry. 53: 4633-4635.  1
1987 Crans DC, Kazlauskas RJ, Hirschbein BL, Wong CH, Abril O, Whitesides GM. Enzymatic regeneration of adenosine 5'-triphosphate: acetyl phosphate, phosphoenolpyruvate, methoxycarbonyl phosphate, dihydroxyacetone phosphate, 5-phospho-alpha-D-ribosyl pyrophosphate, uridine-5'-diphosphoglucose. Methods in Enzymology. 136: 263-80. PMID 2446104 DOI: 10.1016/S0076-6879(87)36027-6  1
1985 Kazlauskas RJ, Whitesides GM. Synthesis of methoxycarbonyl phosphate, a new reagent having high phosphoryl donor potential for use in ATP cofactor regeneration Journal of Organic Chemistry. 50: 1069-1076.  1
1983 Whitesides GM, Kazlauskas RJ, Josephson L. Magnetic separations in biotechnology Trends in Biotechnology. 1: 144-148. DOI: 10.1016/0167-7799(83)90005-7  1
1982 Kazlauskas RJ, Wrighton MS. Application of rapid-scan Fourier transform infrared spectroscopy to characterize the monodentate intermediate in the photochemical formation of tetracarbonyl(4,4′-dialkyl-2,2′-bipyridine)metal from hexacarbonylmetal Journal of the American Chemical Society. 104: 5784-5786.  1
1982 Kazlauskas RJ, Wrighton MS. Photochemistry of alkyldicarbonyl(η5-cyclopentadienyl)iron and -ruthenium. Ligand substitution and alkene elimination via photogenerated 16-valence-electron intermediates Organometallics. 1: 602-611.  1
1982 Kazlauskas RJ, Wrighton MS. Photochemistry of metal carbonyl alkyls. Study of thermal β-hydrogen transfer in photogenerated, 16-valence-electron alkyldicarbonylcyclopentadienylmolybdenum and -tungsten complexes Journal of the American Chemical Society. 104: 6005-6015.  1
1980 Kazlauskas RJ, Wrighton MS. Photogeneration of intermediates involved in catalytic cycles. β-Hydride elimination from the 16-electron alkyl species generated by irradiation of tricarbonyl(η5-cyclopentadienyl)(n-pentyl)tungsten(II) [7] Journal of the American Chemical Society. 102: 1727-1730.  1
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