Michael R. Sawaya - Publications

Affiliations: 
2001- Chemistry University of California, Los Angeles, Los Angeles, CA 

182 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Warmack RA, Boyer DR, Zee CT, Richards LS, Sawaya MR, Cascio D, Gonen T, Eisenberg DS, Clarke SG. Structure of amyloid-β (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface. Nature Communications. 10: 3357. PMID 31350392 DOI: 10.1038/s41467-019-11183-z  1
2019 Cao Q, Boyer DR, Sawaya MR, Ge P, Eisenberg DS. Cryo-EM structures of four polymorphic TDP-43 amyloid cores. Nature Structural & Molecular Biology. PMID 31235914 DOI: 10.1038/s41594-019-0248-4  1
2019 Kattke MD, Gosschalk JE, Martinez OE, Kumar G, Gale RT, Cascio D, Sawaya MR, Philips M, Brown ED, Clubb RT. Structure and mechanism of TagA, a novel membrane-associated glycosyltransferase that produces wall teichoic acids in pathogenic bacteria. Plos Pathogens. 15: e1007723. PMID 31002736 DOI: 10.1371/journal.ppat.1007723  1
2019 Zee CT, Glynn C, Gallagher-Jones M, Miao J, Santiago CG, Cascio D, Gonen T, Sawaya MR, Rodriguez JA. Homochiral and racemic MicroED structures of a peptide repeat from the ice-nucleation protein InaZ. Iucrj. 6: 197-205. PMID 30867917 DOI: 10.1107/S2052252518017621  1
2018 Cao Q, Shin WS, Chan H, Vuong CK, Dubois B, Li B, Murray KA, Sawaya MR, Feigon J, Black DL, Eisenberg DS, Jiang L. Author Correction: Inhibiting amyloid-β cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design. Nature Chemistry. PMID 30420778 DOI: 10.1038/s41557-018-0182-9  1
2018 Tuukkanen AT, Freire D, Chan S, Arbing MA, Reed RW, Evans TJ, Zenkeviciutė G, Kim J, Kahng S, Sawaya MR, Chaton CT, Wilmanns M, Eisenberg D, Parret AHA, Korotkov KV. Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3 and ESX-5 Type VII Secretion Systems. Journal of Molecular Biology. PMID 30419243 DOI: 10.1016/j.jmb.2018.11.003  1
2018 Brumshtein B, Esswein SR, Sawaya MR, Rosenberg G, Ly AT, Landau M, Eisenberg DS. Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light chain amyloidosis. The Journal of Biological Chemistry. PMID 30355736 DOI: 10.1074/jbc.RA118.004142  1
2018 Cao Q, Shin WS, Chan H, Vuong CK, Dubois B, Li B, Murray KA, Sawaya MR, Feigon J, Black DL, Eisenberg DS, Jiang L. Inhibiting amyloid-ß cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design. Nature Chemistry. PMID 30297750 DOI: 10.1038/s41557-018-0147-z  1
2018 Li B, Ge P, Murray KA, Sheth P, Zhang M, Nair G, Sawaya MR, Shin WS, Boyer DR, Ye S, Eisenberg DS, Zhou ZH, Jiang L. Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel. Nature Communications. 9: 3609. PMID 30190461 DOI: 10.1038/s41467-018-05971-2  1
2018 McPartland L, Heller DM, Eisenberg DS, Hochschild A, Sawaya MR. Atomic insights into the genesis of cellular filaments by globular proteins. Nature Structural & Molecular Biology. 25: 705-714. PMID 30076408 DOI: 10.1038/s41594-018-0096-7  1
2018 Guenther EL, Cao Q, Trinh H, Lu J, Sawaya MR, Cascio D, Boyer DR, Rodriguez JA, Hughes MP, Eisenberg DS. Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nature Structural & Molecular Biology. PMID 29786080 DOI: 10.1038/s41594-018-0064-2  1
2018 Saelices L, Sievers SA, Sawaya MR, Eisenberg DS. Crystal Structures of Amyloidogenic Segments of Human Transthyretin. Protein Science : a Publication of the Protein Society. PMID 29626847 DOI: 10.1002/pro.3420  1
2018 Guenther EL, Ge P, Trinh H, Sawaya MR, Cascio D, Boyer DR, Gonen T, Zhou ZH, Eisenberg DS. Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Nature Structural & Molecular Biology. PMID 29531287 DOI: 10.1038/s41594-018-0045-5  1
2018 Sangwan S, Sawaya MR, Murray KA, Hughes M, Eisenberg DS. Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations. Protein Science : a Publication of the Protein Society. PMID 29453800 DOI: 10.1002/pro.3391  1
2018 Hughes MP, Sawaya MR, Boyer DR, Goldschmidt L, Rodriguez JA, Cascio D, Chong L, Gonen T, Eisenberg DS. Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks. Science (New York, N.Y.). 359: 698-701. PMID 29439243 DOI: 10.1126/science.aan6398  1
2018 Seidler PM, Boyer DR, Rodriguez JA, Sawaya MR, Cascio D, Murray K, Gonen T, Eisenberg DS. Structure-based inhibitors of tau aggregation. Nature Chemistry. 10: 170-176. PMID 29359764 DOI: 10.1038/nchem.2889  1
2018 Do TD, Sangwan S, de Almeida NEC, Ilitchev AI, Giammona M, Sawaya MR, Buratto SK, Eisenberg DS, Bowers MT. Distal Amyloid β-Protein Fragments Template Amyloid Assembly. Protein Science : a Publication of the Protein Society. PMID 29349888 DOI: 10.1002/pro.3375  1
2018 Gallagher-Jones M, Glynn C, Boyer DR, Martynowycz MW, Hernandez E, Miao J, Zee CT, Novikova IV, Goldschmidt L, McFarlane HT, Helguera GF, Evans JE, Sawaya MR, Cascio D, Eisenberg DS, et al. Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp. Nature Structural & Molecular Biology. PMID 29335561 DOI: 10.1038/s41594-017-0018-0  1
2017 Krotee P, Griner SL, Sawaya MR, Cascio D, Rodriguez JA, Shi D, Philipp S, Murray K, Saelices L, Lee J, Seidler P, Glabe CG, Jiang L, Gonen T, Eisenberg DS. Common fibrillar spines of amyloid-β and human Islet Amyloid Polypeptide revealed by Micro Electron Diffraction and inhibitors developed using structure-based design. The Journal of Biological Chemistry. PMID 29282295 DOI: 10.1074/jbc.M117.806109  1
2017 Grintsevich EE, Ge P, Sawaya MR, Yesilyurt HG, Terman JR, Zhou ZH, Reisler E. Catastrophic disassembly of actin filaments via Mical-mediated oxidation. Nature Communications. 8: 2183. PMID 29259197 DOI: 10.1038/s41467-017-02357-8  0.44
2017 Hanczyc P, Mikhailovsky AA, Boyer DR, Sawaya MR, Heeger AJ, Eisenberg D. Ultrafast Time-Resolved Studies on Fluorescein for Recognition Strands Architecture in Amyloid Fibrils. The Journal of Physical Chemistry. B. PMID 29237120 DOI: 10.1021/acs.jpcb.7b07923  1
2017 Sangwan S, Zhao A, Adams KL, Jayson CK, Sawaya MR, Guenther EL, Pan AC, Ngo J, Moore DM, Soriaga AB, Do TD, Goldschmidt L, Nelson R, Bowers MT, Koehler CM, et al. Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS). Proceedings of the National Academy of Sciences of the United States of America. PMID 28760994 DOI: 10.1073/pnas.1705091114  1
2017 Eisenberg DS, Sawaya MR. Neurodegeneration: Taming tangled tau. Nature. PMID 28678777 DOI: 10.1038/nature23094  1
2017 Popp D, Loh ND, Zorgati H, Ghoshdastider U, Liow LT, Ivanova MI, Larsson M, DePonte DP, Bean R, Beyerlein KR, Gati C, Oberthuer D, Arnlund D, Brändén G, Berntsen P, ... ... Sawaya MR, et al. Flow-aligned, single-shot fiber diffraction using a femtosecond X-ray free-electron laser. Cytoskeleton (Hoboken, N.J.). PMID 28574190 DOI: 10.1002/cm.21378  1
2017 Tayeb-Fligelman E, Tabachnikov O, Moshe A, Goldshmidt-Tran O, Sawaya MR, Coquelle N, Colletier JP, Landau M. The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril. Science (New York, N.Y.). 355: 831-833. PMID 28232575 DOI: 10.1126/science.aaf4901  0.52
2017 de la Cruz MJ, Hattne J, Shi D, Seidler P, Rodriguez J, Reyes FE, Sawaya MR, Cascio D, Weiss SC, Kim SK, Hinck CS, Hinck AP, Calero G, Eisenberg D, Gonen T. Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nature Methods. PMID 28192420 DOI: 10.1038/nmeth.4178  1
2017 Eisenberg DS, Sawaya MR. Structural Studies of Amyloid Proteins at the Molecular Level. Annual Review of Biochemistry. PMID 28125289 DOI: 10.1146/annurev-biochem-061516-045104  1
2017 Krotee P, Rodriguez JA, Sawaya MR, Cascio D, Reyes FE, Shi D, Hattne J, Nannenga BL, Oskarsson ME, Philipp S, Griner S, Jiang L, Glabe CG, Westermark GT, Gonen T, et al. Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity. Elife. 6. PMID 28045370 DOI: 10.7554/eLife.19273  1
2016 Kattke MD, Chan AH, Duong A, Sexton DL, Sawaya MR, Cascio D, Elliot MA, Clubb RT. Crystal Structure of the Streptomyces coelicolor Sortase E1 Transpeptidase Provides Insight into the Binding Mode of the Novel Class E Sorting Signal. Plos One. 11: e0167763. PMID 27936128 DOI: 10.1371/journal.pone.0167763  1
2016 Flores BN, Dulchavsky ME, Krans A, Sawaya MR, Paulson HL, Todd PK, Barmada SJ, Ivanova MI. Distinct C9orf72-Associated Dipeptide Repeat Structures Correlate with Neuronal Toxicity. Plos One. 11: e0165084. PMID 27776165 DOI: 10.1371/journal.pone.0165084  0.56
2016 Sawaya MR, Verma M, Balendiran V, Rath NP, Cascio D, Balendiran GK. Characterization of WY 14,643 and its Complex with Aldose Reductase. Scientific Reports. 6: 34394. PMID 27721416 DOI: 10.1038/srep34394  1
2016 Colletier JP, Sawaya MR, Gingery M, Rodriguez JA, Cascio D, Brewster AS, Michels-Clark T, Hice RH, Coquelle N, Boutet S, Williams GJ, Messerschmidt M, DePonte DP, Sierra RG, Laksmono H, et al. De novo phasing with X-ray laser reveals mosquito larvicide BinAB structure. Nature. PMID 27680699 DOI: 10.1038/nature19825  1
2016 Sawaya MR, Rodriguez J, Cascio D, Collazo MJ, Shi D, Reyes FE, Hattne J, Gonen T, Eisenberg DS. Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED. Proceedings of the National Academy of Sciences of the United States of America. PMID 27647903 DOI: 10.1073/pnas.1606287113  1
2016 Chowdhury C, Chun S, Sawaya MR, Yeates TO, Bobik TA. The function of the PduJ microcompartment shell protein is determined by the genomic position of its encoding gene. Molecular Microbiology. 101: 770-83. PMID 27561553 DOI: 10.1111/mmi.13423  0.52
2016 Eisenberg DS, Sawaya MR. Implications for Alzheimer's disease of an atomic resolution structure of amyloid-β(1-42) fibrils. Proceedings of the National Academy of Sciences of the United States of America. PMID 27506787 DOI: 10.1073/pnas.1610806113  1
2016 Wheatley NM, Eden KD, Ngo J, Rosinski JS, Sawaya MR, Cascio D, Collazo M, Hoveida H, Hubbell WL, Yeates TO. A PII-like protein regulated by bicarbonate: Structural and biochemical studies of the carboxysome-associated CPII protein. Journal of Molecular Biology. PMID 27464895 DOI: 10.1016/j.jmb.2016.07.015  0.36
2016 Landreh M, Sawaya MR, Hipp MS, Eisenberg DS, Wüthrich K, Hartl FU. The formation, function and regulation of amyloids: insights from structural biology. Journal of Internal Medicine. 280: 164-76. PMID 27237473 DOI: 10.1111/joim.12500  1
2016 Jorda J, Sawaya MR, Yeates TO. Progress in low-resolution ab initio phasing with CrowdPhase. Acta Crystallographica. Section D, Structural Biology. 72: 446-453. PMID 26960132 DOI: 10.1107/S2059798316003405  0.52
2015 Soriaga AB, Sangwan S, Macdonald R, Sawaya MR, Eisenberg D. Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets. The Journal of Physical Chemistry. B. PMID 26629790 DOI: 10.1021/acs.jpcb.5b09981  1
2015 Brumshtein B, Esswein SR, Salwinski L, Phillips ML, Ly AT, Cascio D, Sawaya MR, Eisenberg DS. Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain. Elife. 4. PMID 26576950 DOI: 10.7554/eLife.10935  1
2015 Saelices L, Johnson LM, Liang WY, Sawaya MR, Cascio D, Ruchala P, Whitelegge J, Jiang L, Riek R, Eisenberg DS. Uncovering the Mechanism of Aggregation of Human Transthyretin. The Journal of Biological Chemistry. PMID 26459562 DOI: 10.1074/jbc.M115.659912  1
2015 Xu R, Chen CC, Wu L, Scott MC, Theis W, Ophus C, Bartels M, Yang Y, Ramezani-Dakhel H, Sawaya MR, Heinz H, Marks LD, Ercius P, Miao J. Three-dimensional coordinates of individual atoms in materials revealed by electron tomography. Nature Materials. PMID 26390325 DOI: 10.1038/nmat4426  1
2015 Rodriguez JA, Ivanova MI, Sawaya MR, Cascio D, Reyes FE, Shi D, Sangwan S, Guenther EL, Johnson LM, Zhang M, Jiang L, Arbing MA, Nannenga BL, Hattne J, Whitelegge J, et al. Structure of the toxic core of α-synuclein from invisible crystals. Nature. PMID 26352473 DOI: 10.1038/nature15368  1
2015 Sereda V, Sawaya MR, Lednev IK. Structural Organization of Insulin Fibrils Based on Polarized Raman Spectroscopy: Evaluation of Existing Models. Journal of the American Chemical Society. 137: 11312-20. PMID 26278047 DOI: 10.1021/jacs.5b07535  1
2015 Winter JM, Cascio D, Dietrich D, Sato M, Watanabe K, Sawaya MR, Vederas JC, Tang Y. Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis. Journal of the American Chemical Society. PMID 26172141 DOI: 10.1021/jacs.5b04520  1
2015 Zhang H, Unal H, Gati C, Han GW, Liu W, Zatsepin NA, James D, Wang D, Nelson G, Weierstall U, Sawaya MR, Xu Q, Messerschmidt M, Williams GJ, Boutet S, et al. Structure of the Angiotensin receptor revealed by serial femtosecond crystallography. Cell. 161: 833-44. PMID 25913193 DOI: 10.1016/j.cell.2015.04.011  1
2015 Soragni A, Yousefi S, Stoeckle C, Soriaga AB, Sawaya MR, Kozlowski E, Schmid I, Radonjic-Hoesli S, Boutet S, Williams GJ, Messerschmidt M, Seibert MM, Cascio D, Zatsepin NA, Burghammer M, et al. Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation. Molecular Cell. 57: 1011-21. PMID 25728769 DOI: 10.1016/j.molcel.2015.01.026  1
2015 Chowdhury C, Chun S, Pang A, Sawaya MR, Sinha S, Yeates TO, Bobik TA. Selective molecular transport through the protein shell of a bacterial microcompartment organelle. Proceedings of the National Academy of Sciences of the United States of America. 112: 2990-5. PMID 25713376 DOI: 10.1073/pnas.1423672112  1
2015 Brewster AS, Sawaya MR, Rodriguez J, Hattne J, Echols N, McFarlane HT, Cascio D, Adams PD, Eisenberg DS, Sauter NK. Indexing amyloid peptide diffraction from serial femtosecond crystallography: new algorithms for sparse patterns. Acta Crystallographica. Section D, Biological Crystallography. 71: 357-66. PMID 25664747 DOI: 10.1107/S1399004714026145  1
2015 Vinokur JM, Korman TP, Sawaya MR, Collazo M, Cascio D, Bowie JU. Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases. Protein Science : a Publication of the Protein Society. 24: 212-20. PMID 25422158 DOI: 10.1002/pro.2607  1
2014 Li D, Jones EM, Sawaya MR, Furukawa H, Luo F, Ivanova M, Sievers SA, Wang W, Yaghi OM, Liu C, Eisenberg DS. Structure-based design of functional amyloid materials. Journal of the American Chemical Society. 136: 18044-51. PMID 25474758 DOI: 10.1021/ja509648u  1
2014 Bobik TA, Morales EJ, Shin A, Cascio D, Sawaya MR, Arbing M, Yeates TO, Rasche ME. Structure of the methanofuran/methanopterin-biosynthetic enzyme MJ1099 from Methanocaldococcus jannaschii. Acta Crystallographica. Section F, Structural Biology Communications. 70: 1472-9. PMID 25372812 DOI: 10.1107/S2053230X1402130X  1
2014 Malmirchegini GR, Sjodt M, Shnitkind S, Sawaya MR, Rosinski J, Newton SM, Klebba PE, Clubb RT. Novel mechanism of hemin capture by Hbp2, the hemoglobin-binding hemophore from Listeria monocytogenes. The Journal of Biological Chemistry. 289: 34886-99. PMID 25315777 DOI: 10.1074/jbc.M114.583013  1
2014 Brumshtein B, Esswein SR, Landau M, Ryan CM, Whitelegge JP, Phillips ML, Cascio D, Sawaya MR, Eisenberg DS. Formation of amyloid fibers by monomeric light chain variable domains. The Journal of Biological Chemistry. 289: 27513-25. PMID 25138218 DOI: 10.1074/jbc.M114.585638  1
2014 Sawaya MR, Cascio D, Gingery M, Rodriguez J, Goldschmidt L, Colletier JP, Messerschmidt MM, Boutet S, Koglin JE, Williams GJ, Brewster AS, Nass K, Hattne J, Botha S, Doak RB, et al. Protein crystal structure obtained at 2.9 Å resolution from injecting bacterial cells into an X-ray free-electron laser beam. Proceedings of the National Academy of Sciences of the United States of America. 111: 12769-74. PMID 25136092 DOI: 10.1073/pnas.1413456111  1
2014 Thompson MC, Wheatley NM, Jorda J, Sawaya MR, Gidaniyan SD, Ahmed H, Yang Z, McCarty KN, Whitelegge JP, Yeates TO. Identification of a unique Fe-S cluster binding site in a glycyl-radical type microcompartment shell protein. Journal of Molecular Biology. 426: 3287-304. PMID 25102080 DOI: 10.1016/j.jmb.2014.07.018  1
2014 Do TD, LaPointe NE, Sangwan S, Teplow DB, Feinstein SC, Sawaya MR, Eisenberg DS, Bowers MT. Factors that drive peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants. The Journal of Physical Chemistry. B. 118: 7247-56. PMID 24915112 DOI: 10.1021/jp502473s  1
2014 Jorda J, Sawaya MR, Yeates TO. CrowdPhase: crowdsourcing the phase problem. Acta Crystallographica. Section D, Biological Crystallography. 70: 1538-48. PMID 24914965 DOI: 10.1107/S1399004714006427  1
2014 Sinha S, Cheng S, Sung YW, McNamara DE, Sawaya MR, Yeates TO, Bobik TA. Alanine scanning mutagenesis identifies an asparagine-arginine-lysine triad essential to assembly of the shell of the Pdu microcompartment. Journal of Molecular Biology. 426: 2328-45. PMID 24747050 DOI: 10.1016/j.jmb.2014.04.012  1
2014 Jiménez-Osés G, Osuna S, Gao X, Sawaya MR, Gilson L, Collier SJ, Huisman GW, Yeates TO, Tang Y, Houk KN. The role of distant mutations and allosteric regulation on LovD active site dynamics. Nature Chemical Biology. 10: 431-6. PMID 24727900 DOI: 10.1038/nchembio.1503  1
2014 Hochberg GK, Ecroyd H, Liu C, Cox D, Cascio D, Sawaya MR, Collier MP, Stroud J, Carver JA, Baldwin AJ, Robinson CV, Eisenberg DS, Benesch JL, Laganowsky A. The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity. Proceedings of the National Academy of Sciences of the United States of America. 111: E1562-70. PMID 24711386 DOI: 10.1073/pnas.1322673111  1
2014 Okamoto R, Mandal K, Sawaya MR, Kajihara Y, Yeates TO, Kent SB. (Quasi-)racemic X-ray structures of glycosylated and non-glycosylated forms of the chemokine Ser-CCL1 prepared by total chemical synthesis. Angewandte Chemie (International Ed. in English). 53: 5194-8. PMID 24692304 DOI: 10.1002/anie.201400679  1
2014 Ivanova MI, Sievers SA, Guenther EL, Johnson LM, Winkler DD, Galaleldeen A, Sawaya MR, Hart PJ, Eisenberg DS. Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS. Proceedings of the National Academy of Sciences of the United States of America. 111: 197-201. PMID 24344300 DOI: 10.1073/pnas.1320786110  1
2014 Sawaya MR. Methods to refine macromolecular structures in cases of severe diffraction anisotropy. Methods in Molecular Biology (Clifton, N.J.). 1091: 205-14. PMID 24203335 DOI: 10.1007/978-1-62703-691-7_15  1
2013 Arbing MA, Chan S, Harris L, Kuo E, Zhou TT, Ahn CJ, Nguyen L, He Q, Lu J, Menchavez PT, Shin A, Holton T, Sawaya MR, Cascio D, Eisenberg D. Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions. Plos One. 8: e81753. PMID 24312350 DOI: 10.1371/journal.pone.0081753  1
2013 Lai YT, Tsai KL, Sawaya MR, Asturias FJ, Yeates TO. Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly. Journal of the American Chemical Society. 135: 7738-43. PMID 23621606 DOI: 10.1021/ja402277f  1
2013 Wang P, Bashiri G, Gao X, Sawaya MR, Tang Y. Uncovering the enzymes that catalyze the final steps in oxytetracycline biosynthesis. Journal of the American Chemical Society. 135: 7138-41. PMID 23621493 DOI: 10.1021/ja403516u  1
2013 Zhu C, Chen CC, Du J, Sawaya MR, Scott MC, Ercius P, Ciston J, Miao J. Towards three-dimensional structural determination of amorphous materials at atomic resolution Physical Review B - Condensed Matter and Materials Physics. 88. DOI: 10.1103/PhysRevB.88.100201  1
2013 Sawaya MR, Eisenberg D. Amyloid Structures at the Atomic Level: Insights from Crystallography Amyloid Fibrils and Prefibrillar Aggregates: Molecular and Biological Properties. 21-38. DOI: 10.1002/9783527654185.ch2  1
2012 Liu C, Zhao M, Jiang L, Cheng PN, Park J, Sawaya MR, Pensalfini A, Gou D, Berk AJ, Glabe CG, Nowick J, Eisenberg D. Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates. Proceedings of the National Academy of Sciences of the United States of America. 109: 20913-8. PMID 23213214 DOI: 10.1073/pnas.1218792109  1
2012 Min AB, Miallau L, Sawaya MR, Habel J, Cascio D, Eisenberg D. The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg²⁺ ion in the active site and a putative RNA-binding site. Protein Science : a Publication of the Protein Society. 21: 1754-67. PMID 23011806 DOI: 10.1002/pro.2161  1
2012 Durer ZA, Kudryashov DS, Sawaya MR, Altenbach C, Hubbell W, Reisler E. Structural states and dynamics of the D-loop in actin. Biophysical Journal. 103: 930-9. PMID 23009842 DOI: 10.1016/j.bpj.2012.07.030  1
2012 King NP, Sheffler W, Sawaya MR, Vollmar BS, Sumida JP, André I, Gonen T, Yeates TO, Baker D. Computational design of self-assembling protein nanomaterials with atomic level accuracy. Science (New York, N.Y.). 336: 1171-4. PMID 22654060 DOI: 10.1126/science.1219364  1
2012 Kato M, Han TW, Xie S, Shi K, Du X, Wu LC, Mirzaei H, Goldsmith EJ, Longgood J, Pei J, Grishin NV, Frantz DE, Schneider JW, Chen S, Li L, ... Sawaya MR, et al. Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels. Cell. 149: 753-67. PMID 22579281 DOI: 10.1016/j.cell.2012.04.017  1
2012 Laganowsky A, Liu C, Sawaya MR, Whitelegge JP, Park J, Zhao M, Pensalfini A, Soriaga AB, Landau M, Teng PK, Cascio D, Glabe C, Eisenberg D. Atomic view of a toxic amyloid small oligomer. Science (New York, N.Y.). 335: 1228-31. PMID 22403391 DOI: 10.1126/science.1213151  1
2012 Chen CK, Sawaya MR, Phillips ML, Reisler E, Quinlan ME. Multiple forms of Spire-actin complexes and their functional consequences. The Journal of Biological Chemistry. 287: 10684-92. PMID 22334675 DOI: 10.1074/jbc.M111.317792  1
2012 Sawaya MR, Pentelute BL, Kent SB, Yeates TO. Single-wavelength phasing strategy for quasi-racemic protein crystal diffraction data. Acta Crystallographica. Section D, Biological Crystallography. 68: 62-8. PMID 22194334 DOI: 10.1107/S0907444911049985  1
2012 Teng PK, Anderson NJ, Goldschmidt L, Sawaya MR, Sambashivan S, Eisenberg D. Ribonuclease A suggests how proteins self-chaperone against amyloid fiber formation. Protein Science : a Publication of the Protein Society. 21: 26-37. PMID 22095666 DOI: 10.1002/pro.754  1
2011 Pickens LB, Sawaya MR, Rasool H, Pashkov I, Yeates TO, Tang Y. Structural and biochemical characterization of the salicylyl-acyltranferase SsfX3 from a tetracycline biosynthetic pathway. The Journal of Biological Chemistry. 286: 41539-51. PMID 21965680 DOI: 10.1074/jbc.M111.299859  1
2011 Colletier JP, Laganowsky A, Landau M, Zhao M, Soriaga AB, Goldschmidt L, Flot D, Cascio D, Sawaya MR, Eisenberg D. Molecular basis for amyloid-beta polymorphism. Proceedings of the National Academy of Sciences of the United States of America. 108: 16938-43. PMID 21949245 DOI: 10.1073/pnas.1112600108  1
2011 Laganowsky A, Zhao M, Soriaga AB, Sawaya MR, Cascio D, Yeates TO. An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Science : a Publication of the Protein Society. 20: 1876-90. PMID 21898649 DOI: 10.1002/pro.727  1
2011 Landau M, Sawaya MR, Faull KF, Laganowsky A, Jiang L, Sievers SA, Liu J, Barrio JR, Eisenberg D. Towards a pharmacophore for amyloid. Plos Biology. 9: e1001080. PMID 21695112 DOI: 10.1371/journal.pbio.1001080  1
2011 Chaptal V, Kwon S, Sawaya MR, Guan L, Kaback HR, Abramson J. Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition. Proceedings of the National Academy of Sciences of the United States of America. 108: 9361-6. PMID 21593407 DOI: 10.1073/pnas.1105687108  1
2011 Liu C, Sawaya MR, Cheng PN, Zheng J, Nowick JS, Eisenberg D. Characteristics of amyloid-related oligomers revealed by crystal structures of macrocyclic β-sheet mimics. Journal of the American Chemical Society. 133: 6736-44. PMID 21473620 DOI: 10.1021/ja200222n  1
2011 Stafford RL, Tang MY, Sawaya MR, Phillips ML, Bowie JU. Crystal structure of the central coiled-coil domain from human liprin-β2 Biochemistry. 50: 3807-3815. PMID 21462929 DOI: 10.1021/bi200141e  1
2011 Zhao M, Cascio D, Sawaya MR, Eisenberg D. Structures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation. Protein Science : a Publication of the Protein Society. 20: 996-1004. PMID 21462277 DOI: 10.1002/pro.630  1
2011 Tullius MV, Harmston CA, Owens CP, Chim N, Morse RP, McMath LM, Iniguez A, Kimmey JM, Sawaya MR, Whitelegge JP, Horwitz MA, Goulding CW. Discovery and characterization of a unique mycobacterial heme acquisition system. Proceedings of the National Academy of Sciences of the United States of America. 108: 5051-6. PMID 21383189 DOI: 10.1073/pnas.1009516108  1
2011 Apostol MI, Wiltzius JJ, Sawaya MR, Cascio D, Eisenberg D. Atomic structures suggest determinants of transmission barriers in mammalian prion disease. Biochemistry. 50: 2456-63. PMID 21323366 DOI: 10.1021/bi101803k  1
2011 Zheng J, Liu C, Sawaya MR, Vadla B, Khan S, Woods RJ, Eisenberg D, Goux WJ, Nowick JS. Macrocyclic β-sheet peptides that inhibit the aggregation of a tau-protein-derived hexapeptide. Journal of the American Chemical Society. 133: 3144-57. PMID 21319744 DOI: 10.1021/ja110545h  1
2011 Liu C, Sawaya MR, Eisenberg D. β₂-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages. Nature Structural & Molecular Biology. 18: 49-55. PMID 21131979 DOI: 10.1038/nsmb.1948  1
2011 Balendiran GK, Sawaya MR, Schwarz FP, Ponniah G, Cuckovich R, Verma M, Cascio D. The role of Cys-298 in aldose reductase function. The Journal of Biological Chemistry. 286: 6336-44. PMID 21084309 DOI: 10.1074/jbc.M110.154195  1
2011 Forse GJ, Ram N, Banatao DR, Cascio D, Sawaya MR, Klock HE, Lesley SA, Yeates TO. Synthetic symmetrization in the crystallization and structure determination of CelA from Thermotoga maritima. Protein Science : a Publication of the Protein Society. 20: 168-78. PMID 21082721 DOI: 10.1002/pro.550  1
2010 King NP, Jacobitz AW, Sawaya MR, Goldschmidt L, Yeates TO. Structure and folding of a designed knotted protein. Proceedings of the National Academy of Sciences of the United States of America. 107: 20732-7. PMID 21068371 DOI: 10.1073/pnas.1007602107  1
2010 Hsieh JM, Tsirulnikov K, Sawaya MR, Magilnick N, Abuladze N, Kurtz I, Abramson J, Pushkin A. Structures of aminoacylase 3 in complex with acetylated substrates. Proceedings of the National Academy of Sciences of the United States of America. 107: 17962-7. PMID 20921362 DOI: 10.1073/pnas.1006687107  1
2010 Pentelute BL, Mandal K, Gates ZP, Sawaya MR, Yeates TO, Kent SB. Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography. Chemical Communications (Cambridge, England). 46: 8174-6. PMID 20877851 DOI: 10.1039/c0cc03148h  1
2010 Crowley CS, Cascio D, Sawaya MR, Kopstein JS, Bobik TA, Yeates TO. Structural insight into the mechanisms of transport across the Salmonella enterica Pdu microcompartment shell. The Journal of Biological Chemistry. 285: 37838-46. PMID 20870711 DOI: 10.1074/jbc.M110.160580  1
2010 Mura C, McCrimmon CM, Vertrees J, Sawaya MR. An introduction to biomolecular graphics. Plos Computational Biology. 6. PMID 20865174 DOI: 10.1371/journal.pcbi.1000918  1
2010 Apostol MI, Sawaya MR, Cascio D, Eisenberg D. Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease. The Journal of Biological Chemistry. 285: 29671-5. PMID 20685658 DOI: 10.1074/jbc.C110.158303  1
2010 Khakshoor O, Lin AJ, Korman TP, Sawaya MR, Tsai SC, Eisenberg D, Nowick JS. X-ray crystallographic structure of an artificial beta-sheet dimer. Journal of the American Chemical Society. 132: 11622-8. PMID 20669960 DOI: 10.1021/ja103438w  1
2010 Banigan JR, Mandal K, Sawaya MR, Thammavongsa V, Hendrickx AP, Schneewind O, Yeates TO, Kent SB. Determination of the X-ray structure of the snake venom protein omwaprin by total chemical synthesis and racemic protein crystallography. Protein Science : a Publication of the Protein Society. 19: 1840-9. PMID 20669184 DOI: 10.1002/pro.468  1
2010 Ostapchenko VG, Sawaya MR, Makarava N, Savtchenko R, Nilsson KP, Eisenberg D, Baskakov IV. Two amyloid States of the prion protein display significantly different folding patterns. Journal of Molecular Biology. 400: 908-21. PMID 20553730 DOI: 10.1016/j.jmb.2010.05.051  1
2010 Senturia R, Faller M, Yin S, Loo JA, Cascio D, Sawaya MR, Hwang D, Clubb RT, Guo F. Structure of the dimerization domain of DiGeorge critical region 8. Protein Science : a Publication of the Protein Society. 19: 1354-65. PMID 20506313 DOI: 10.1002/pro.414  1
2010 Laganowsky A, Benesch JL, Landau M, Ding L, Sawaya MR, Cascio D, Huang Q, Robinson CV, Horwitz J, Eisenberg D. Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Science : a Publication of the Protein Society. 19: 1031-43. PMID 20440841 DOI: 10.1002/pro.380  1
2010 Wang L, Schubert D, Sawaya MR, Eisenberg D, Riek R. Multidimensional structure-activity relationship of a protein in its aggregated states. Angewandte Chemie (International Ed. in English). 49: 3904-8. PMID 20397175 DOI: 10.1002/anie.201000068  1
2010 Chan S, Giuroiu I, Chernishof I, Sawaya MR, Chiang J, Gunsalus RP, Arbing MA, Perry LJ. Apo and ligand-bound structures of ModA from the archaeon Methanosarcina acetivorans. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 242-50. PMID 20208152 DOI: 10.1107/S1744309109055158  1
2010 Tanaka S, Sawaya MR, Yeates TO. Structure and mechanisms of a protein-based organelle in Escherichia coli. Science (New York, N.Y.). 327: 81-4. PMID 20044574 DOI: 10.1126/science.1179513  1
2009 Gao X, Xie X, Pashkov I, Sawaya MR, Laidman J, Zhang W, Cacho R, Yeates TO, Tang Y. Directed evolution and structural characterization of a simvastatin synthase. Chemistry & Biology. 16: 1064-74. PMID 19875080 DOI: 10.1016/j.chembiol.2009.09.017  1
2009 Ivanova MI, Sievers SA, Sawaya MR, Wall JS, Eisenberg D. Molecular basis for insulin fibril assembly. Proceedings of the National Academy of Sciences of the United States of America. 106: 18990-5. PMID 19864624 DOI: 10.1073/pnas.0910080106  1
2009 Tsai Y, Sawaya MR, Yeates TO. Analysis of lattice-translocation disorder in the layered hexagonal structure of carboxysome shell protein CsoS1C. Acta Crystallographica. Section D, Biological Crystallography. 65: 980-8. PMID 19690376 DOI: 10.1107/S0907444909025153  1
2009 Wiltzius JJ, Landau M, Nelson R, Sawaya MR, Apostol MI, Goldschmidt L, Soriaga AB, Cascio D, Rajashankar K, Eisenberg D. Molecular mechanisms for protein-encoded inheritance. Nature Structural & Molecular Biology. 16: 973-8. PMID 19684598 DOI: 10.1038/nsmb.1643  1
2009 Han GW, Rife C, Sawaya MR. Applications of bioinformatics to protein structures: how protein structure and bioinformatics overlap. Methods in Molecular Biology (Clifton, N.J.). 569: 157-72. PMID 19623490 DOI: 10.1007/978-1-59745-524-4_8  1
2009 Maji SK, Perrin MH, Sawaya MR, Jessberger S, Vadodaria K, Rissman RA, Singru PS, Nilsson KP, Simon R, Schubert D, Eisenberg D, Rivier J, Sawchenko P, Vale W, Riek R. Functional amyloids as natural storage of peptide hormones in pituitary secretory granules. Science (New York, N.Y.). 325: 328-32. PMID 19541956 DOI: 10.1126/science.1173155  1
2009 Wiltzius JJ, Sievers SA, Sawaya MR, Eisenberg D. Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process. Protein Science : a Publication of the Protein Society. 18: 1521-30. PMID 19475663 DOI: 10.1002/pro.145  1
2009 Afshar S, Sawaya MR, Morrison SL. Structure of a mutant human purine nucleoside phosphorylase with the prodrug, 2-fluoro-2'-deoxyadenosine and the cytotoxic drug, 2-fluoroadenine. Protein Science : a Publication of the Protein Society. 18: 1107-14. PMID 19388075 DOI: 10.1002/pro.91  1
2009 Kollman JM, Pandi L, Sawaya MR, Riley M, Doolittle RF. Crystal structure of human fibrinogen. Biochemistry. 48: 3877-86. PMID 19296670 DOI: 10.1021/bi802205g  1
2009 Tanaka S, Sawaya MR, Phillips M, Yeates TO. Insights from multiple structures of the shell proteins from the beta-carboxysome. Protein Science : a Publication of the Protein Society. 18: 108-20. PMID 19177356 DOI: 10.1002/pro.14  1
2008 Zhang K, Sawaya MR, Eisenberg DS, Liao JC. Expanding metabolism for biosynthesis of nonnatural alcohols. Proceedings of the National Academy of Sciences of the United States of America. 105: 20653-8. PMID 19064911 DOI: 10.1073/pnas.0807157106  1
2008 Kudryashov DS, Durer ZA, Ytterberg AJ, Sawaya MR, Pashkov I, Prochazkova K, Yeates TO, Loo RR, Loo JA, Satchell KJ, Reisler E. Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin. Proceedings of the National Academy of Sciences of the United States of America. 105: 18537-42. PMID 19015515 DOI: 10.1073/pnas.0808082105  1
2008 Sawaya MR, Wojtowicz WM, Andre I, Qian B, Wu W, Baker D, Eisenberg D, Zipursky SL. A double S shape provides the structural basis for the extraordinary binding specificity of Dscam isoforms. Cell. 134: 1007-18. PMID 18805093 DOI: 10.1016/j.cell.2008.07.042  1
2008 Crowley CS, Sawaya MR, Bobik TA, Yeates TO. Structure of the PduU shell protein from the Pdu microcompartment of Salmonella. Structure (London, England : 1993). 16: 1324-32. PMID 18786396 DOI: 10.1016/j.str.2008.05.013  1
2008 Beverly KN, Sawaya MR, Schmid E, Koehler CM. The Tim8-Tim13 Complex Has Multiple Substrate Binding Sites and Binds Cooperatively to Tim23 Journal of Molecular Biology. 382: 1144-1156. PMID 18706423 DOI: 10.1016/j.jmb.2008.07.069  1
2008 Wang L, Maji SK, Sawaya MR, Eisenberg D, Riek R. Bacterial inclusion bodies contain amyloid-like structure. Plos Biology. 6: e195. PMID 18684013 DOI: 10.1371/journal.pbio.0060195  1
2008 Wiltzius JJ, Sievers SA, Sawaya MR, Cascio D, Popov D, Riekel C, Eisenberg D. Atomic structure of the cross-beta spine of islet amyloid polypeptide (amylin). Protein Science : a Publication of the Protein Society. 17: 1467-74. PMID 18556473 DOI: 10.1110/ps.036509.108  1
2008 King NP, Lee TM, Sawaya MR, Cascio D, Yeates TO. Structures and functional implications of an AMP-binding cystathionine beta-synthase domain protein from a hyperthermophilic archaeon. Journal of Molecular Biology. 380: 181-92. PMID 18513746 DOI: 10.1016/j.jmb.2008.04.073  1
2008 Sawaya MR, Kudryashov DS, Pashkov I, Adisetiyo H, Reisler E, Yeates TO. Multiple crystal structures of actin dimers and their implications for interactions in the actin filament. Acta Crystallographica. Section D, Biological Crystallography. 64: 454-65. PMID 18391412 DOI: 10.1107/S0907444908003351  1
2008 Harada BT, Knight MJ, Imai Si, Qiao F, Ramachander R, Sawaya MR, Gingery M, Sakane F, Bowie JU. Regulation of Enzyme Localization by Polymerization: Polymer Formation by the SAM Domain of Diacylglycerol Kinase δ1 Structure. 16: 380-387. PMID 18334213 DOI: 10.1016/j.str.2007.12.017  1
2008 Tanaka S, Kerfeld CA, Sawaya MR, Cai F, Heinhorst S, Cannon GC, Yeates TO. Atomic-level models of the bacterial carboxysome shell. Science (New York, N.Y.). 319: 1083-6. PMID 18292340 DOI: 10.1126/science.1151458  1
2007 Tanaka S, Sawaya MR, Kerfeld CA, Yeates TO. Structure of the RuBisCO chaperone RbcX from Synechocystis sp. PCC6803. Acta Crystallographica. Section D, Biological Crystallography. 63: 1109-12. PMID 17881829 DOI: 10.1107/S090744490704228X  1
2007 Tsai Y, Sawaya MR, Cannon GC, Cai F, Williams EB, Heinhorst S, Kerfeld CA, Yeates TO. Structural analysis of CsoS1A and the protein shell of the Halothiobacillus neapolitanus carboxysome. Plos Biology. 5: e144. PMID 17518518 DOI: 10.1371/journal.pbio.0050144  1
2007 Yeates TO, Tsai Y, Tanaka S, Sawaya MR, Kerfeld CA. Self-assembly in the carboxysome: a viral capsid-like protein shell in bacterial cells. Biochemical Society Transactions. 35: 508-11. PMID 17511640 DOI: 10.1042/BST0350508  1
2007 Sawaya MR, Sambashivan S, Nelson R, Ivanova MI, Sievers SA, Apostol MI, Thompson MJ, Balbirnie M, Wiltzius JJ, McFarlane HT, Madsen AØ, Riekel C, Eisenberg D. Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature. 447: 453-7. PMID 17468747 DOI: 10.1038/nature05695  1
2007 Sawaya MR. Characterizing a crystal from an initial native dataset. Methods in Molecular Biology (Clifton, N.J.). 364: 95-120. PMID 17172762 DOI: 10.1385/1-59745-266-1:95  1
2006 Eisenberg D, Nelson R, Sawaya MR, Balbirnie M, Sambashivan S, Ivanova MI, Madsen AØ, Riekel C. The structural biology of protein aggregation diseases: Fundamental questions and some answers. Accounts of Chemical Research. 39: 568-75. PMID 16981672 DOI: 10.1021/ar0500618  1
2006 Nicoll DA, Sawaya MR, Kwon S, Cascio D, Philipson KD, Abramson J. The crystal structure of the primary Ca2+ sensor of the Na+/Ca2+ exchanger reveals a novel Ca2+ binding motif. The Journal of Biological Chemistry. 281: 21577-81. PMID 16774926 DOI: 10.1074/jbc.C600117200  1
2006 Bennett MJ, Sawaya MR, Eisenberg D. Deposition diseases and 3D domain swapping. Structure (London, England : 1993). 14: 811-24. PMID 16698543 DOI: 10.1016/j.str.2006.03.011  1
2006 Strong M, Sawaya MR, Wang S, Phillips M, Cascio D, Eisenberg D. Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 8060-5. PMID 16690741 DOI: 10.1073/pnas.0602606103  1
2006 Baron MK, Boeckers TM, Vaida B, Faham S, Gingery M, Sawaya MR, Salyer D, Gundelfinger ED, Bowie JU. An architectural framework that may lie at the core of the postsynaptic density. Science (New York, N.Y.). 311: 531-5. PMID 16439662 DOI: 10.1126/science.1118995  1
2006 Sawaya MR, Cannon GC, Heinhorst S, Tanaka S, Williams EB, Yeates TO, Kerfeld CA. The structure of beta-carbonic anhydrase from the carboxysomal shell reveals a distinct subclass with one active site for the price of two. The Journal of Biological Chemistry. 281: 7546-55. PMID 16407248 DOI: 10.1074/jbc.M510464200  1
2005 Sawaya MR, Zhu Z, Mersha F, Chan SH, Dabur R, Xu SY, Balendiran GK. Crystal structure of the restriction-modification system control element C.BclI and mapping of its binding site Structure. 13: 1837-1847. PMID 16338412 DOI: 10.1016/j.str.2005.08.017  1
2005 Sambashivan S, Liu Y, Sawaya MR, Gingery M, Eisenberg D. Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure. Nature. 437: 266-9. PMID 16148936 DOI: 10.1038/nature03916  1
2005 Kudryashov DS, Sawaya MR, Adisetiyo H, Norcross T, Hegyi G, Reisler E, Yeates TO. The crystal structure of a cross-linked actin dimer suggests a detailed molecular interface in F-actin. Proceedings of the National Academy of Sciences of the United States of America. 102: 13105-10. PMID 16141336 DOI: 10.1073/pnas.0506429102  1
2005 Kerfeld CA, Sawaya MR, Tanaka S, Nguyen CV, Phillips M, Beeby M, Yeates TO. Protein structures forming the shell of primitive bacterial organelles. Science (New York, N.Y.). 309: 936-8. PMID 16081736 DOI: 10.1126/science.1113397  1
2005 Nelson R, Sawaya MR, Balbirnie M, Madsen A, Riekel C, Grothe R, Eisenberg D. Structure of the cross-β spine of amyloid-like fibrils Nature. 435: 773-778. PMID 15944695 DOI: 10.1038/nature03680  1
2005 Kim CA, Sawaya MR, Cascio D, Kim W, Bowie JU. Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer. The Journal of Biological Chemistry. 280: 27769-75. PMID 15905166 DOI: 10.1074/jbc.M503055200  1
2005 Li H, Sawaya MR, Tabita FR, Eisenberg D. Crystal structure of a RuBisCO-like protein from the green sulfur bacterium Chlorobium tepidum. Structure (London, England : 1993). 13: 779-89. PMID 15893668 DOI: 10.1016/j.str.2005.02.017  1
2005 Goulding CW, Apostol MI, Sawaya MR, Phillips M, Parseghian A, Eisenberg D. Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme. Journal of Molecular Biology. 349: 61-72. PMID 15876368 DOI: 10.1016/j.jmb.2005.03.023  1
2005 Johnson E, Cascio D, Sawaya MR, Gingery M, Schröder I. Crystal structures of a tetrahedral open pore ferritin from the hyperthermophilic archaeon Archaeoglobus fulgidus. Structure (London, England : 1993). 13: 637-48. PMID 15837202 DOI: 10.1016/j.str.2005.01.019  1
2005 Merchant S, Sawaya MR. The light reactions: A guide to recent acquisitions for the picture gallery Plant Cell. 17: 648-663. PMID 15746074 DOI: 10.1105/tpc.105.030676  1
2005 Müller P, Sawaya MR, Pashkov I, Chan S, Nguyen C, Wu Y, Perry LJ, Eisenberg D. The 1.70 Å X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase Acta Crystallographica Section D: Biological Crystallography. 61: 309-315. PMID 15735341 DOI: 10.1107/S0907444904033190  1
2004 Grzeskowiak K, Sawaya MR, Ohishi H, Tomoo K, Ishida T. Function of AGCA tetrads in (CAG)n repeats. Nucleic Acids Symposium Series (2004). 291-2. PMID 17150593 DOI: 10.1093/nass/48.1.291  1
2004 Chan S, Segelke B, Lekin T, Krupka H, Cho US, Kim MY, So M, Kim CY, Naranjo CM, Rogers YC, Park MS, Waldo GS, Pashkov I, Cascio D, Perry JL, ... Sawaya MR, et al. Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism. Journal of Molecular Biology. 341: 503-17. PMID 15276840 DOI: 10.1016/j.jmb.2004.06.028  1
2004 Qiao F, Song H, Kim CA, Sawaya MR, Hunter JB, Gingery M, Rebay I, Courey AJ, Bowie JU. Derepression by depolymerization; structural insights into the regulation of Yan by Mae. Cell. 118: 163-73. PMID 15260987 DOI: 10.1016/j.cell.2004.07.010  1
2004 Ivanova MI, Sawaya MR, Gingery M, Attinger A, Eisenberg D. An amyloid-forming segment of beta2-microglobulin suggests a molecular model for the fibril. Proceedings of the National Academy of Sciences of the United States of America. 101: 10584-9. PMID 15249659 DOI: 10.1073/pnas.0403756101  1
2003 Lee S, Sawaya MR, Eisenberg D. Structure of superoxide dismutase from Pyrobaculum aerophilum presents a challenging case in molecular replacement with multiple molecules, pseudo-symmetry and twinning. Acta Crystallographica. Section D, Biological Crystallography. 59: 2191-9. PMID 14646077 DOI: 10.1107/S0907444903019942  1
2003 Toth EA, Li Y, Sawaya MR, Cheng Y, Ellenberger T. The crystal structure of the bifunctional primase-helicase of bacteriophage T7 Molecular Cell. 12: 1113-1123. PMID 14636571 DOI: 10.1016/S1097-2765(03)00442-8  1
2003 Goulding CW, Perry LJ, Anderson D, Sawaya MR, Cascio D, Apostol MI, Chan S, Parseghian A, Wang SS, Wu Y, Cassano V, Gill HS, Eisenberg D. Structural genomics of Mycobacterium tuberculosis: a preliminary report of progress at UCLA. Biophysical Chemistry. 105: 361-70. PMID 14499904 DOI: 10.1016/S0301-4622(03)00101-7  1
2003 Kerfeld CA, Sawaya MR, Bottin H, Tran KT, Sugiura M, Cascio D, Desbois A, Yeates TO, Kirilovsky D, Boussac A. Structural and EPR characterization of the soluble form of cytochrome c-550 and of the psbV2 gene product from the cyanobacterium Thermosynechococcus elongatus. Plant & Cell Physiology. 44: 697-706. PMID 12881497 DOI: 10.1093/pcp/pcg084  1
2003 Han GW, Kopka ML, Langs D, Sawaya MR, Dickerson RE. Crystal structure of an RNA·DNA hybrid reveals intermolecular intercalation: Dimer formation by base-pair swapping Proceedings of the National Academy of Sciences of the United States of America. 100: 9214-9219. PMID 12872000 DOI: 10.1073/pnas.1533326100  1
2003 Chaudhuri BN, Sawaya MR, Kim CY, Waldo GS, Park MS, Terwilliger TC, Yeates TO. The crystal structure of the first enzyme in the pantothenate biosynthetic pathway, ketopantoate hydroxymethyltransferase, from M tuberculosis. Structure (London, England : 1993). 11: 753-64. PMID 12842039 DOI: 10.1016/S0969-2126(03)00106-0  1
2003 Kerfeld CA, Sawaya MR, Brahmandam V, Cascio D, Ho KK, Trevithick-Sutton CC, Krogmann DW, Yeates TO. The crystal structure of a cyanobacterial water-soluble carotenoid binding protein. Structure (London, England : 1993). 11: 55-65. PMID 12517340 DOI: 10.1016/S0969-2126(02)00936-X  1
2003 Anderson DH, Sawaya MR, Cascio D, Ernst W, Modlin R, Krensky A, Eisenberg D. Granulysin crystal structure and a structure-derived lytic mechanism. Journal of Molecular Biology. 325: 355-65. PMID 12488100 DOI: 10.1016/S0022-2836(02)01234-2  1
2002 Goulding CW, Parseghian A, Sawaya MR, Cascio D, Apostol MI, Gennaro ML, Eisenberg D. Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at 1.5-A resolution. Protein Science : a Publication of the Protein Society. 11: 2887-93. PMID 12441386 DOI: 10.1110/ps.0219002  1
2002 Maris AE, Sawaya MR, Kaczor-Grzeskowiak M, Jarvis MR, Bearson SM, Kopka ML, Schröder I, Gunsalus RP, Dickerson RE. Dimerization allows DNA target site recognition by the NarL response regulator. Nature Structural Biology. 9: 771-8. PMID 12352954 DOI: 10.1038/nsb845  1
2002 Kerfeld CA, Sawaya MR, Krogmann DW, Yeates TO. Structure of cytochrome c6 from Arthrospira maxima: An assembly of 24 subunits in a nearly symmetric shell Acta Crystallographica Section D: Biological Crystallography. 58: 1104-1110. PMID 12077429 DOI: 10.1107/S0907444902006534  1
2002 Goulding CW, Sawaya MR, Parseghian A, Lim V, Eisenberg D, Missiakas D. Thiol-disulfide exchange in an immunoglobulin-like fold: Structure of the N-terminal domain of DsbD Biochemistry. 41: 6920-6927. PMID 12033924 DOI: 10.1021/bi016038l  1
2002 Wang S, Mura C, Sawaya MR, Cascio D, Eisenberg D. Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets. Acta Crystallographica. Section D, Biological Crystallography. 58: 571-8. PMID 11914479 DOI: 10.1107/S0907444902001191  1
2002 Ryttersgaard C, Griffith SC, Sawaya MR, MacLaren DC, Clarke S, Yeates TO. Crystal structure of human L-isoaspartyl methyltransferase. The Journal of Biological Chemistry. 277: 10642-6. PMID 11792715 DOI: 10.1074/jbc.M200229200  1
2001 Griffith SC, Sawaya MR, Boutz DR, Thapar N, Katz JE, Clarke S, Yeates TO. Crystal structure of a protein repair methyltransferase from Pyrococcus furiosus with its L-isoaspartyl peptide substrate. Journal of Molecular Biology. 313: 1103-16. PMID 11700066 DOI: 10.1006/jmbi.2001.5095  1
2001 Sawaya MR, Krogmann DW, Serag A, Kwok Ki Ho, Yeates TO, Kerfeld CA. Structures of cytochrome c-549 and cytochrome c6 from the cyanobacterium Arthrospira maxima Biochemistry. 40: 9215-9225. PMID 11478889 DOI: 10.1021/bi002679p  1
2001 Mura C, Cascio D, Sawaya MR, Eisenberg DS. The crystal structure of a heptameric archaeal Sm protein: Implications for the eukaryotic snRNP core. Proceedings of the National Academy of Sciences of the United States of America. 98: 5532-7. PMID 11331747 DOI: 10.1073/pnas.091102298  1
2001 Han GW, Lee JY, Song HK, Chang C, Min K, Moon J, Shin DH, Kopka ML, Sawaya MR, Yuan HS, Kim TD, Choe J, Lim D, Moon HJ, Suh SW. Structural basis of non-specific lipid binding in maize lipid-transfer protein complexes revealed by high-resolution X-ray crystallography. Journal of Molecular Biology. 308: 263-78. PMID 11327766 DOI: 10.1006/jmbi.2001.4559  1
2000 Singleton MR, Sawaya MR, Ellenberger T, Wigley DB. Crystal structure of T7 gene 4 ring indicates a mechanism for sequential hydrolysis of nucleotides Cell. 101: 589-600. PMID 10892646  1
1999 Sawaya MR, Guo S, Tabor S, Richardson CC, Ellenberger T. Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7 Cell. 99: 167-177. PMID 10535735  1
1999 Doublié S, Sawaya MR, Ellenberger T. An open and closed case for all polymerases Structure. 7: R31-R35. PMID 10368292 DOI: 10.1016/S0969-2126(99)80017-3  1
1997 Sawaya MR, Prasad R, Wilson SH, Kraut J, Pelletier H. Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism. Biochemistry. 36: 11205-15. PMID 9287163 DOI: 10.1021/bi9703812  1
1997 Sawaya MR, Kraut J. Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry. 36: 586-603. PMID 9012674 DOI: 10.1021/bi962337c  1
1996 Pelletier H, Sawaya MR, Wolfle W, Wilson SH, Kraut J. A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta. Biochemistry. 35: 12762-77. PMID 8841119 DOI: 10.1021/bi9529566  1
1996 Pelletier H, Sawaya MR, Wolfle W, Wilson SH, Kraut J. Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity. Biochemistry. 35: 12742-61. PMID 8841118 DOI: 10.1021/bi952955d  1
1996 Beard WA, Osheroff WP, Prasad R, Sawaya MR, Jaju M, Wood TG, Kraut J, Kunkel TA, Wilson SH. Enzyme-DNA interactions required for efficient nucleotide incorporation and discrimination in human DNA polymerase beta. The Journal of Biological Chemistry. 271: 12141-4. PMID 8647805 DOI: 10.1074/jbc.271.21.12141  1
1995 Reyes VM, Sawaya MR, Brown KA, Kraut J. Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications. Biochemistry. 34: 2710-23. PMID 7873554  1
1994 Sawaya MR, Pelletier H, Kumar A, Wilson SH, Kraut J. Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism. Science (New York, N.Y.). 264: 1930-5. PMID 7516581  1
1994 Pelletier H, Sawaya MR, Kumar A, Wilson SH, Kraut J. Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. Science (New York, N.Y.). 264: 1891-903. PMID 7516580  1
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