Michael R. Sawaya - Publications

Affiliations: 
2001- Chemistry University of California, Los Angeles, Los Angeles, CA 

67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Abskharon R, Seidler P, Sawaya MR, Cascio D, Philipp S, Glabe CG, Eisenberg DS. ATOMIC STRUCTURES OF A SINGLE CHAIN ANTIBODY THAT BINDS AND INHIBITS SEEDING BY TAU OLIGOMERS Alzheimer's & Dementia. 15: P1599. DOI: 10.1016/J.Jalz.2019.09.061  0.315
2018 Tuukkanen AT, Freire D, Chan S, Arbing MA, Reed RW, Evans TJ, Zenkeviciutė G, Kim J, Kahng S, Sawaya MR, Chaton CT, Wilmanns M, Eisenberg D, Parret AHA, Korotkov KV. Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3 and ESX-5 Type VII Secretion Systems. Journal of Molecular Biology. PMID 30419243 DOI: 10.1016/J.Jmb.2018.11.003  0.317
2018 McPartland L, Heller DM, Eisenberg DS, Hochschild A, Sawaya MR. Atomic insights into the genesis of cellular filaments by globular proteins. Nature Structural & Molecular Biology. 25: 705-714. PMID 30076408 DOI: 10.1107/S0108767318095995  0.358
2018 Guenther EL, Cao Q, Trinh H, Lu J, Sawaya MR, Cascio D, Boyer DR, Rodriguez JA, Hughes MP, Eisenberg DS. Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nature Structural & Molecular Biology. PMID 29786080 DOI: 10.1038/S41594-018-0064-2  0.374
2018 Guenther EL, Ge P, Trinh H, Sawaya MR, Cascio D, Boyer DR, Gonen T, Zhou ZH, Eisenberg DS. Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Nature Structural & Molecular Biology. PMID 29531287 DOI: 10.1038/S41594-018-0045-5  0.378
2018 Sangwan S, Sawaya MR, Murray KA, Hughes M, Eisenberg DS. Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations. Protein Science : a Publication of the Protein Society. PMID 29453800 DOI: 10.1002/Pro.3391  0.342
2017 Krotee P, Griner SL, Sawaya MR, Cascio D, Rodriguez JA, Shi D, Philipp S, Murray K, Saelices L, Lee J, Seidler P, Glabe CG, Jiang L, Gonen T, Eisenberg DS. Common fibrillar spines of amyloid-β and human Islet Amyloid Polypeptide revealed by Micro Electron Diffraction and inhibitors developed using structure-based design. The Journal of Biological Chemistry. PMID 29282295 DOI: 10.1074/Jbc.M117.806109  0.32
2017 Eisenberg DS, Sawaya MR. Structural Studies of Amyloid Proteins at the Molecular Level. Annual Review of Biochemistry. PMID 28125289 DOI: 10.1146/Annurev-Biochem-061516-045104  0.364
2016 Sawaya MR, Rodriguez J, Cascio D, Collazo MJ, Shi D, Reyes FE, Hattne J, Gonen T, Eisenberg DS. Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED. Proceedings of the National Academy of Sciences of the United States of America. PMID 27647903 DOI: 10.1073/Pnas.1606287113  0.362
2015 Soriaga AB, Sangwan S, Macdonald R, Sawaya MR, Eisenberg D. Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets. The Journal of Physical Chemistry. B. PMID 26629790 DOI: 10.1021/Acs.Jpcb.5B09981  0.301
2014 Do TD, LaPointe NE, Sangwan S, Teplow DB, Feinstein SC, Sawaya MR, Eisenberg DS, Bowers MT. Factors that drive peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants. The Journal of Physical Chemistry. B. 118: 7247-56. PMID 24915112 DOI: 10.1021/Jp502473S  0.37
2014 Eisenberg D, Laganowsky A, Liu C, Sawaya M, Whitelegge J, Zhao M, Soriaga A, Landau M, Teng P, Cascio D, Jiang L, Sievers S, Soragni A. Structural Studies of the Amyloid State of Proteins Acta Crystallographica Section a Foundations and Advances. 70: C797-C797. DOI: 10.1107/S205327331409202X  0.395
2013 Lai YT, Tsai KL, Sawaya MR, Asturias FJ, Yeates TO. Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly. Journal of the American Chemical Society. 135: 7738-43. PMID 23621606 DOI: 10.1021/Ja402277F  0.345
2012 Min AB, Miallau L, Sawaya MR, Habel J, Cascio D, Eisenberg D. The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg²⁺ ion in the active site and a putative RNA-binding site. Protein Science : a Publication of the Protein Society. 21: 1754-67. PMID 23011806 DOI: 10.1002/Pro.2161  0.363
2012 Chen CK, Sawaya MR, Phillips ML, Reisler E, Quinlan ME. Multiple forms of Spire-actin complexes and their functional consequences. The Journal of Biological Chemistry. 287: 10684-92. PMID 22334675 DOI: 10.1074/Jbc.M111.317792  0.363
2012 Zheng J, Liu C, Sawaya MR, Vadla B, Khan S, Woods RJ, Eisenberg D, Goux WJ, Nowick JS. Correction to Macrocyclic β-Sheet Peptides That Inhibit the Aggregation of a Tau-Protein-Derived Hexapeptide Journal of the American Chemical Society. 134: 17832-17832. DOI: 10.1021/Ja308086H  0.32
2011 Pickens LB, Sawaya MR, Rasool H, Pashkov I, Yeates TO, Tang Y. Structural and biochemical characterization of the salicylyl-acyltranferase SsfX3 from a tetracycline biosynthetic pathway. The Journal of Biological Chemistry. 286: 41539-51. PMID 21965680 DOI: 10.1074/Jbc.M111.299859  0.37
2011 Colletier JP, Laganowsky A, Landau M, Zhao M, Soriaga AB, Goldschmidt L, Flot D, Cascio D, Sawaya MR, Eisenberg D. Molecular basis for amyloid-beta polymorphism. Proceedings of the National Academy of Sciences of the United States of America. 108: 16938-43. PMID 21949245 DOI: 10.1073/Pnas.1112600108  0.394
2011 Chaptal V, Kwon S, Sawaya MR, Guan L, Kaback HR, Abramson J. Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition. Proceedings of the National Academy of Sciences of the United States of America. 108: 9361-6. PMID 21593407 DOI: 10.1073/pnas.1105687108  0.316
2011 Liu C, Sawaya MR, Cheng PN, Zheng J, Nowick JS, Eisenberg D. Characteristics of amyloid-related oligomers revealed by crystal structures of macrocyclic β-sheet mimics. Journal of the American Chemical Society. 133: 6736-44. PMID 21473620 DOI: 10.1021/Ja200222N  0.387
2011 Stafford RL, Tang MY, Sawaya MR, Phillips ML, Bowie JU. Crystal structure of the central coiled-coil domain from human liprin-β2 Biochemistry. 50: 3807-3815. PMID 21462929 DOI: 10.1021/Bi200141E  0.382
2011 Apostol MI, Wiltzius JJ, Sawaya MR, Cascio D, Eisenberg D. Atomic structures suggest determinants of transmission barriers in mammalian prion disease. Biochemistry. 50: 2456-63. PMID 21323366 DOI: 10.1021/Bi101803K  0.313
2011 Liu C, Sawaya MR, Eisenberg D. β₂-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages. Nature Structural & Molecular Biology. 18: 49-55. PMID 21131979 DOI: 10.1038/Nsmb.1948  0.379
2011 Yeates T, Thompson M, Sheng F, Kopstein J, Sawaya M, Cascio D, Crowley C. Structure and function of protein-based metabolic organelles in bacteria Acta Crystallographica Section a Foundations of Crystallography. 67: C36-C36. DOI: 10.1107/S010876731109920X  0.322
2010 King NP, Jacobitz AW, Sawaya MR, Goldschmidt L, Yeates TO. Structure and folding of a designed knotted protein. Proceedings of the National Academy of Sciences of the United States of America. 107: 20732-7. PMID 21068371 DOI: 10.1073/Pnas.1007602107  0.38
2010 Crowley CS, Cascio D, Sawaya MR, Kopstein JS, Bobik TA, Yeates TO. Structural insight into the mechanisms of transport across the Salmonella enterica Pdu microcompartment shell. The Journal of Biological Chemistry. 285: 37838-46. PMID 20870711 DOI: 10.1074/Jbc.M110.160580  0.396
2010 Mura C, McCrimmon CM, Vertrees J, Sawaya MR. An introduction to biomolecular graphics. Plos Computational Biology. 6. PMID 20865174 DOI: 10.1371/Journal.Pcbi.1000918  0.522
2010 Apostol MI, Sawaya MR, Cascio D, Eisenberg D. Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease. The Journal of Biological Chemistry. 285: 29671-5. PMID 20685658 DOI: 10.1074/Jbc.C110.158303  0.398
2010 Khakshoor O, Lin AJ, Korman TP, Sawaya MR, Tsai SC, Eisenberg D, Nowick JS. X-ray crystallographic structure of an artificial beta-sheet dimer. Journal of the American Chemical Society. 132: 11622-8. PMID 20669960 DOI: 10.1021/Ja103438W  0.415
2010 Laganowsky A, Benesch JL, Landau M, Ding L, Sawaya MR, Cascio D, Huang Q, Robinson CV, Horwitz J, Eisenberg D. Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Science : a Publication of the Protein Society. 19: 1031-43. PMID 20440841 DOI: 10.1002/Pro.380  0.332
2010 Chan S, Giuroiu I, Chernishof I, Sawaya MR, Chiang J, Gunsalus RP, Arbing MA, Perry LJ. Apo and ligand-bound structures of ModA from the archaeon Methanosarcina acetivorans. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 242-50. PMID 20208152 DOI: 10.1107/S1744309109055158  0.317
2010 Tanaka S, Sawaya MR, Yeates TO. Structure and mechanisms of a protein-based organelle in Escherichia coli. Science (New York, N.Y.). 327: 81-4. PMID 20044574 DOI: 10.1126/Science.1179513  0.423
2009 Maji SK, Perrin MH, Sawaya MR, Jessberger S, Vadodaria K, Rissman RA, Singru PS, Nilsson KP, Simon R, Schubert D, Eisenberg D, Rivier J, Sawchenko P, Vale W, Riek R. Functional amyloids as natural storage of peptide hormones in pituitary secretory granules. Science (New York, N.Y.). 325: 328-32. PMID 19541956 DOI: 10.1126/Science.1173155  0.31
2009 Kollman JM, Pandi L, Sawaya MR, Riley M, Doolittle RF. Crystal structure of human fibrinogen. Biochemistry. 48: 3877-86. PMID 19296670 DOI: 10.1021/Bi802205G  0.417
2008 King NP, Lee TM, Sawaya MR, Cascio D, Yeates TO. Structures and functional implications of an AMP-binding cystathionine beta-synthase domain protein from a hyperthermophilic archaeon. Journal of Molecular Biology. 380: 181-92. PMID 18513746 DOI: 10.1016/J.Jmb.2008.04.073  0.32
2008 Tanaka S, Kerfeld CA, Sawaya MR, Cai F, Heinhorst S, Cannon GC, Yeates TO. Atomic-level models of the bacterial carboxysome shell. Science (New York, N.Y.). 319: 1083-6. PMID 18292340 DOI: 10.1107/S0108767308089459  0.369
2006 Strong M, Sawaya MR, Wang S, Phillips M, Cascio D, Eisenberg D. Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 8060-5. PMID 16690741 DOI: 10.1073/Pnas.0602606103  0.383
2006 Baron MK, Boeckers TM, Vaida B, Faham S, Gingery M, Sawaya MR, Salyer D, Gundelfinger ED, Bowie JU. An architectural framework that may lie at the core of the postsynaptic density. Science (New York, N.Y.). 311: 531-5. PMID 16439662 DOI: 10.1126/Science.1118995  0.33
2005 Sambashivan S, Liu Y, Sawaya MR, Gingery M, Eisenberg D. Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure. Nature. 437: 266-9. PMID 16148936 DOI: 10.1038/Nature03916  0.328
2005 Kudryashov DS, Sawaya MR, Adisetiyo H, Norcross T, Hegyi G, Reisler E, Yeates TO. The crystal structure of a cross-linked actin dimer suggests a detailed molecular interface in F-actin. Proceedings of the National Academy of Sciences of the United States of America. 102: 13105-10. PMID 16141336 DOI: 10.1073/Pnas.0506429102  0.325
2005 Kerfeld CA, Sawaya MR, Tanaka S, Nguyen CV, Phillips M, Beeby M, Yeates TO. Protein structures forming the shell of primitive bacterial organelles. Science (New York, N.Y.). 309: 936-8. PMID 16081736 DOI: 10.1126/Science.1113397  0.406
2005 Li H, Sawaya MR, Tabita FR, Eisenberg D. Crystal structure of a RuBisCO-like protein from the green sulfur bacterium Chlorobium tepidum. Structure (London, England : 1993). 13: 779-89. PMID 15893668 DOI: 10.1016/J.Str.2005.02.017  0.351
2005 Eisenberg D, Nelson R, Sawaya MR, Balbirnie M, Madsen AØ, Riekel C, Sambashivan S, Liu Y, Gingery M, Grothe R. Structural studies of amyloid Acta Crystallographica Section a Foundations of Crystallography. 61: c8-c8. DOI: 10.1107/S0108767305099666  0.368
2005 Kerfeld CA, Sawaya MR, Tanaka S, Beeby M, Laidman J, Yeates TO. Structural studies on carboxysomes Acta Crystallographica Section a Foundations of Crystallography. 61: c92-c92. DOI: 10.1107/S010876730509611X  0.37
2004 Chan S, Segelke B, Lekin T, Krupka H, Cho US, Kim MY, So M, Kim CY, Naranjo CM, Rogers YC, Park MS, Waldo GS, Pashkov I, Cascio D, Perry JL, ... Sawaya MR, et al. Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism. Journal of Molecular Biology. 341: 503-17. PMID 15276840 DOI: 10.1016/J.Jmb.2004.06.028  0.304
2003 Toth EA, Li Y, Sawaya MR, Cheng Y, Ellenberger T. The crystal structure of the bifunctional primase-helicase of bacteriophage T7 Molecular Cell. 12: 1113-1123. PMID 14636571 DOI: 10.1016/S1097-2765(03)00442-8  0.638
2003 Han GW, Kopka ML, Langs D, Sawaya MR, Dickerson RE. Crystal structure of an RNA·DNA hybrid reveals intermolecular intercalation: Dimer formation by base-pair swapping Proceedings of the National Academy of Sciences of the United States of America. 100: 9214-9219. PMID 12872000 DOI: 10.1073/Pnas.1533326100  0.347
2003 Chaudhuri BN, Sawaya MR, Kim CY, Waldo GS, Park MS, Terwilliger TC, Yeates TO. The crystal structure of the first enzyme in the pantothenate biosynthetic pathway, ketopantoate hydroxymethyltransferase, from M tuberculosis. Structure (London, England : 1993). 11: 753-64. PMID 12842039 DOI: 10.1016/S0969-2126(03)00106-0  0.354
2002 Goulding CW, Parseghian A, Sawaya MR, Cascio D, Apostol MI, Gennaro ML, Eisenberg D. Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at 1.5-A resolution. Protein Science : a Publication of the Protein Society. 11: 2887-93. PMID 12441386 DOI: 10.1110/Ps.0219002  0.317
2002 Maris AE, Sawaya MR, Kaczor-Grzeskowiak M, Jarvis MR, Bearson SM, Kopka ML, Schröder I, Gunsalus RP, Dickerson RE. Dimerization allows DNA target site recognition by the NarL response regulator. Nature Structural Biology. 9: 771-8. PMID 12352954 DOI: 10.1038/Nsb845  0.313
2002 Goulding CW, Sawaya MR, Parseghian A, Lim V, Eisenberg D, Missiakas D. Thiol-disulfide exchange in an immunoglobulin-like fold: Structure of the N-terminal domain of DsbD Biochemistry. 41: 6920-6927. PMID 12033924 DOI: 10.1021/Bi016038L  0.323
2002 Wang S, Mura C, Sawaya MR, Cascio D, Eisenberg D. Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets. Acta Crystallographica. Section D, Biological Crystallography. 58: 571-8. PMID 11914479 DOI: 10.1107/S0907444902001191  0.603
2002 Kerfeld CA, Sawaya MR, Brahmandan V, Krogmann DW, Ho KK, Yeates TO. The structure of the orange carotenoid protein Acta Crystallographica Section a Foundations of Crystallography. 58: c238-c238. DOI: 10.1107/S0108767302094527  0.371
2001 Mura C, Cascio D, Sawaya MR, Eisenberg DS. The crystal structure of a heptameric archaeal Sm protein: Implications for the eukaryotic snRNP core. Proceedings of the National Academy of Sciences of the United States of America. 98: 5532-7. PMID 11331747 DOI: 10.1073/Pnas.091102298  0.599
2000 Singleton MR, Sawaya MR, Ellenberger T, Wigley DB. Crystal structure of T7 gene 4 ring indicates a mechanism for sequential hydrolysis of nucleotides Cell. 101: 589-600. PMID 10892646 DOI: 10.1016/S0092-8674(00)80871-5  0.653
1999 Sawaya MR, Guo S, Tabor S, Richardson CC, Ellenberger T. Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7 Cell. 99: 167-177. PMID 10535735 DOI: 10.1016/S0092-8674(00)81648-7  0.649
1999 Doublié S, Sawaya MR, Ellenberger T. An open and closed case for all polymerases Structure. 7: R31-R35. PMID 10368292 DOI: 10.1016/S0969-2126(99)80017-3  0.713
1997 Sawaya MR, Prasad R, Wilson SH, Kraut J, Pelletier H. Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism. Biochemistry. 36: 11205-15. PMID 9287163 DOI: 10.1021/Bi9703812  0.64
1997 Sawaya MR, Kraut J. Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry. 36: 586-603. PMID 9012674 DOI: 10.1021/Bi962337C  0.586
1996 Pelletier H, Sawaya MR, Wolfle W, Wilson SH, Kraut J. A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta. Biochemistry. 35: 12762-77. PMID 8841119 DOI: 10.1021/Bi9529566  0.609
1996 Pelletier H, Sawaya MR, Wolfle W, Wilson SH, Kraut J. Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity. Biochemistry. 35: 12742-61. PMID 8841118 DOI: 10.1021/Bi952955D  0.636
1996 Skidmore MO, Sawaya MR, Parkin S, Rupp B, Hope H, Everse SJ, Walter G. Crystallization of the A alpha subunit of protein phosphatase 2A. Protein Science : a Publication of the Protein Society. 5: 1198-200. PMID 8762154 DOI: 10.1002/Pro.5560050625  0.341
1996 Beard WA, Osheroff WP, Prasad R, Sawaya MR, Jaju M, Wood TG, Kraut J, Kunkel TA, Wilson SH. Enzyme-DNA interactions required for efficient nucleotide incorporation and discrimination in human DNA polymerase beta. The Journal of Biological Chemistry. 271: 12141-4. PMID 8647805 DOI: 10.1074/Jbc.271.21.12141  0.607
1995 Reyes VM, Sawaya MR, Brown KA, Kraut J. Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications. Biochemistry. 34: 2710-23. PMID 7873554 DOI: 10.1021/Bi00008A039  0.552
1994 Sawaya MR, Pelletier H, Kumar A, Wilson SH, Kraut J. Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism. Science (New York, N.Y.). 264: 1930-5. PMID 7516581 DOI: 10.1126/Science.7516581  0.64
1994 Pelletier H, Sawaya MR, Kumar A, Wilson SH, Kraut J. Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. Science (New York, N.Y.). 264: 1891-903. PMID 7516580 DOI: 10.1126/Science.7516580  0.634
1994 Pelletier H, Sawaya M, Kumar A, Wilson S, Kraut J. Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP Science. 264: 1891-1903. DOI: 10.1126/SCIENCE.7516580  0.317
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