Yali Dou, Ph.D. - Publications

the histone genes and tubulin genes of the ciliated protozoan Tetrahymena thermophila

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Year Citation  Score
2020 Liu L, Inoki A, Fan K, Mao F, Shi G, Jin X, Zhao M, Ney G, Jones MA, Sun S, Dou Y, Inoki K, Qi L, Li Q. ER associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activity. Blood. PMID 33150381 DOI: 10.1182/blood.2020007975  0.32
2020 Zhang Z, Zong C, Jiang M, Hu H, Cheng X, Ni J, Yi X, Jiang B, Tian F, Chang MW, Su W, Zhu L, Li J, Xiang X, Miao C, ... ... Dou Y, et al. Hepatic HuR modulates lipid homeostasis in response to high-fat diet. Nature Communications. 11: 3067. PMID 32546794 DOI: 10.1038/s41467-020-16918-x  0.32
2020 Li J, Wang W, Zhang Y, Cieślik M, Guo J, Tan M, Green MD, Wang W, Lin H, Li W, Wei S, Zhou J, Li G, Jing X, Vatan L, ... ... Dou Y, et al. Epigenetic driver mutations in ARID1A shape cancer immune phenotype and immunotherapy. The Journal of Clinical Investigation. PMID 32027624 DOI: 10.1172/JCI134402  0.32
2019 Klossowski S, Miao H, Kempinska K, Wu T, Purohit T, Kim E, Linhares BM, Chen D, Jih G, Perkey E, Huang H, He M, Wen B, Wang Y, Yu K, ... ... Dou Y, et al. Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia. The Journal of Clinical Investigation. PMID 31855575 DOI: 10.1172/JCI129126  1
2019 Bazopoulou D, Knoefler D, Zheng Y, Ulrich K, Oleson BJ, Xie L, Kim M, Kaufmann A, Lee YT, Dou Y, Chen Y, Quan S, Jakob U. Developmental ROS individualizes organismal stress resistance and lifespan. Nature. PMID 31801997 DOI: 10.1038/s41586-019-1814-y  0.32
2019 Hu H, Jiang M, Cao Y, Zhang Z, Jiang B, Tian F, Feng J, Dou Y, Gorospe M, Zheng M, Zheng L, Yang Z, Wang W. HuR regulates phospholamban expression in isoproterenol-induced cardiac remodeling. Cardiovascular Research. PMID 31373621 DOI: 10.1093/cvr/cvz205  0.32
2018 Tang H, Wang H, Cheng X, Fan X, Yang F, Zhang M, Chen Y, Tian Y, Liu C, Shao D, Jiang B, Dou Y, Cong Y, Xing J, Zhang X, et al. Author Correction: HuR regulates telomerase activity through TERC methylation. Nature Communications. 9: 2721. PMID 29988036 DOI: 10.1038/s41467-018-05213-5  0.32
2018 Liu Y, Dou Y. Re-SET for Transcription. Molecular Cell. 70: 985-986. PMID 29932907 DOI: 10.1016/j.molcel.2018.06.010  1
2018 Tang H, Wang H, Cheng X, Fan X, Yang F, Zhang M, Chen Y, Tian Y, Liu C, Shao D, Jiang B, Dou Y, Cong Y, Xing J, Zhang X, et al. HuR regulates telomerase activity through TERC methylation. Nature Communications. 9: 2213. PMID 29880812 DOI: 10.1038/s41467-018-04617-7  0.32
2017 Karatas H, Li Y, Liu L, Ji J, Lee S, Chen Y, Yang J, Huang L, Bernard D, Xu J, Townsend EC, Cao F, Ran X, Li X, Wen B, ... ... Dou Y, et al. Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)-Mixed Lineage Leukemia (MLL) Protein-Protein Interaction. Journal of Medicinal Chemistry. PMID 28603984 DOI: 10.1021/acs.jmedchem.6b01796  0.32
2017 Li Q, Li X, Tang H, Jiang B, Dou Y, Gorospe M, Wang W. NSUN2-mediated m5C Methylation and METTL3/METTL14-mediated m6A Methylation Cooperatively Enhance p21 Translation. Journal of Cellular Biochemistry. PMID 28247949 DOI: 10.1002/jcb.25957  0.32
2016 Liu L, Lei I, Karatas H, Li Y, Wang L, Gnatovskiy L, Dou Y, Wang S, Qian L, Wang Z. Targeting Mll1 H3K4 methyltransferase activity to guide cardiac lineage specific reprogramming of fibroblasts. Cell Discovery. 2: 16036. PMID 27924221 DOI: 10.1038/celldisc.2016.36  0.32
2016 Luo H, Shenoy AK, Li X, Jin Y, Jin L, Cai Q, Tang M, Liu Y, Chen H, Reisman D, Wu L, Seto E, Qiu Y, Dou Y, Casero RA, et al. MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition. Cell Reports. PMID 27292636 DOI: 10.1016/j.celrep.2016.05.050  1
2016 Wang W, Kryczek I, Dostál L, Lin H, Tan L, Zhao L, Lu F, Wei S, Maj T, Peng D, He G, Vatan L, Szeliga W, Kuick R, Kotarski J, ... ... Dou Y, et al. Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer. Cell. PMID 27133165 DOI: 10.1016/j.cell.2016.04.009  1
2016 Zhang H, Gayen S, Xiong J, Zhou B, Shanmugam AK, Sun Y, Karatas H, Liu L, Rao RC, Wang S, Nesvizhskii AI, Kalantry S, Dou Y. MLL1 Inhibition Reprograms Epiblast Stem Cells to Naive Pluripotency. Cell Stem Cell. PMID 26996599 DOI: 10.1016/j.stem.2016.02.004  1
2016 Dou Y, Wang W, Tang Y. Clinical significance of expression of miR-145 in gastric cancer World Chinese Journal of Digestology. 23: 5683-5687. DOI: 10.11569/wcjd.v23.i35.5683  0.32
2016 Tian Y, Song X, Xie Z, Gao J, Dou Y, Li B, Lin J, Tomie T. Sharpening of the 6.8 nm peak in an Nd:YAG laser produced Gd plasma by using a pre-formed plasma Aip Advances. 6. DOI: 10.1063/1.4943976  0.96
2016 Li Y, Dou Y, Qin X, Zhang J, Xin H, Li D, Song C, Zou T, Liu Y, Li C. Enhanced thermoelectric figure of merit in p-type β-Zn4Sb3/Bi0.4Sb1.6Te3 nanocomposites Rsc Advances. 6: 12243-12248. DOI: 10.1039/c5ra25012a  1
2016 Zhou B, Wang J, Lee SY, Xiong J, Bhanu N, Guo Q, Ma P, Sun Y, Rao RC, Garcia BA, Hess JL, Dou Y. PRDM16 Suppresses MLL1r Leukemia via Intrinsic Histone Methyltransferase Activity Molecular Cell. 62: 222-236. DOI: 10.1016/j.molcel.2016.03.010  1
2015 Zeng N, Tong B, Zhang X, Dou Y, Wu X, Xia Y, Dai Y, Wei Z. Antiarthritis Effect of Morin is Associated with Inhibition of Synovial Angiogensis. Drug Development Research. 76: 463-73. PMID 26769128 DOI: 10.1002/ddr.21282  0.32
2015 Tang H, Fan X, Xing J, Liu Z, Jiang B, Dou Y, Gorospe M, Wang W. NSun2 delays replicative senescence by repressing p27 (KIP1) translation and elevating CDK1 translation. Aging. PMID 26687548  0.32
2015 Yuan X, Tong B, Dou Y, Wu X, Wei Z, Dai Y. Tetrandrine ameliorates collagen-induced arthritis in mice by restoring the balance between Th17 and Treg cells via the aryl hydrocarbon receptor. Biochemical Pharmacology. PMID 26640276 DOI: 10.1016/j.bcp.2015.11.025  0.32
2015 Zhang Y, Li W, Dou Y, Zhang J, Jiang G, Miao L, Han G, Liu Y, Li H, Zhang Z. Transcript Quantification by RNA-Seq Reveals Differentially Expressed Genes in the Red and Yellow Fruits of Fragaria vesca. Plos One. 10: e0144356. PMID 26636322 DOI: 10.1371/journal.pone.0144356  1
2015 Peng D, Kryczek I, Nagarsheth N, Zhao L, Wei S, Wang W, Sun Y, Zhao E, Vatan L, Szeliga W, Kotarski J, Tarkowski R, Dou Y, Cho K, Hensley-Alford S, et al. Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy. Nature. PMID 26503055 DOI: 10.1038/nature15520  0.32
2015 Luo J, Liu M, Wu X, Dou Y, Xia Y, Dai Y, Wei Z. DGAEE, a newly synthesized derivative of glycyrrhetinic acid, potently attenuates mouse septic shock via its main metabolite DGA in an IL-10-dependent manner. International Immunopharmacology. PMID 26456500 DOI: 10.1016/j.intimp.2015.09.025  0.32
2015 Liu X, Zhou A, Dou Y, Pan T, Shao M, Han J, Wei M. Ultrafast switching of an electrochromic device based on layered double hydroxide/Prussian blue multilayered films. Nanoscale. PMID 26420230 DOI: 10.1039/c5nr04458h  0.32
2015 Wang T, Wei ZF, Dou YN, Xia YF, Dai Y. [Effect of Madecassoside on Intestinal Mucosal Immunity in Collagen-Induced Arthritis Rats]. Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials. 38: 333-8. PMID 26415412  0.32
2015 Chen C, Zhu X, Dou Y, Xu J, Zhang J, Fan T, Du J, Liu K, Deng Y, Zhao L, Huang Y. Exendin-4 Loaded Nanoparticles with a Lipid Shell and Aqueous Core Containing Micelles for Enhanced Intestinal Absorption. Journal of Biomedical Nanotechnology. 11: 865-76. PMID 26349398 DOI: 10.1166/jbn.2015.1971  0.32
2015 Khan M, Walters LL, Li Q, Thomas DG, Miller JM, Zhang Q, Sciallis AP, Liu Y, Dlouhy BJ, Fort PE, Archer SM, Demirci H, Dou Y, Rao RC. Characterization and pharmacologic targeting of EZH2, a fetal retinal protein and epigenetic regulator, in human retinoblastoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 26280220 DOI: 10.1038/labinvest.2015.104  1
2015 Chen Y, Zhang J, Wang W, Wang Z, Dou Y, Wei D. [The clinical outcomes of thymectomy combined with radiotherapy or cyclophosphamide treatment for myasthenia gravis patients with thymoma]. Zhonghua Nei Ke Za Zhi. 54: 201-204. PMID 26269441  0.32
2015 Wang C, Jiang L, Wang S, Shi H, Wang J, Wang R, Li Y, Dou Y, Liu Y, Hou G, Ke Y, Liu H. The Antitumor Activity of the Novel Compound Jesridonin on Human Esophageal Carcinoma Cells. Plos One. 10: e0130284. PMID 26103161 DOI: 10.1371/journal.pone.0130284  1
2015 Ren R, Sun G, Yang Y, Peng L, Zhang X, Wang S, Dou Y, Zhang X, Wang Z, Bo X, Liu Q, Li W, Fan N, Ma X. [A pilot study of treating ulcerative colitis with fecal microbiota transplantation]. Zhonghua Nei Ke Za Zhi. 54: 411-5. PMID 26080819  0.32
2015 Wu X, Dou Y, Yang Y, Bian D, Luo J, Tong B, Xia Y, Dai Y. Arctigenin exerts anti-colitis efficacy through inhibiting the differentiation of Th1 and Th17 cells via an mTORC1-dependent pathway. Biochemical Pharmacology. PMID 26074264 DOI: 10.1016/j.bcp.2015.06.008  0.32
2015 Liu M, Dou Y, Sun R, Zhang Y, Liu Y. Molecular mechanisms for alcoholic hepatitis based on analysis of gene expression profile. Hepatitis Monthly. 15: e27336. PMID 26045708 DOI: 10.5812/hepatmon.15(5)2015.27336  1
2015 Rao RC, Dou Y. Hijacked in cancer: the KMT2 (MLL) family of methyltransferases. Nature Reviews. Cancer. 15: 334-46. PMID 25998713 DOI: 10.1038/nrc3929  1
2015 Zhao P, Dou Y, Chen L, Li L, Wei Z, Yu J, Wu X, Dai Y, Xia Y. SC-III3, a novel scopoletin derivative, induces autophagy of human hepatoma HepG2 cells through AMPK/mTOR signaling pathway by acting on mitochondria. Fitoterapia. 104: 31-40. PMID 25964188 DOI: 10.1016/j.fitote.2015.05.002  0.32
2015 Jones M, Chase J, Brinkmeier M, Xu J, Weinberg DN, Schira J, Friedman A, Malek S, Grembecka J, Cierpicki T, Dou Y, Camper SA, Maillard I. Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells. The Journal of Clinical Investigation. 125: 2007-20. PMID 25866973 DOI: 10.1172/JCI78124  1
2015 Yang Y, Wu X, Wei Z, Dou Y, Zhao D, Wang T, Bian D, Tong B, Xia Y, Xia Y, Dai Y. Oral curcumin has anti-arthritic efficacy through somatostatin generation via cAMP/PKA and Ca(2+)/CaMKII signaling pathways in the small intestine. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 95: 71-81. PMID 25836921 DOI: 10.1016/j.phrs.2015.03.016  0.32
2015 Shu H, Wang Z, Ye F, Li Q, Dou Y, Lin Y, Huang W, Xiao X. High-dose pentazocine antagonizes the antinociception induced by high-dose morphine. Life Sciences. 130: 1-6. PMID 25817230 DOI: 10.1016/j.lfs.2015.02.023  0.32
2015 Lee YT, Gibbons G, Lee SY, Nikolovska-Coleska Z, Dou Y. One-pot refolding of core histones from bacterial inclusion bodies allows rapid reconstitution of histone octamer. Protein Expression and Purification. 110: 89-94. PMID 25687285 DOI: 10.1016/j.pep.2015.02.007  1
2015 Tong B, Yu J, Wang T, Dou Y, Wu X, Kong L, Dai Y, Xia Y. Sinomenine suppresses collagen-induced arthritis by reciprocal modulation of regulatory T cells and Th17 cells in gut-associated lymphoid tissues. Molecular Immunology. 65: 94-103. PMID 25656802 DOI: 10.1016/j.molimm.2015.01.014  0.32
2015 Wang T, Wei Z, Dou Y, Yang Y, Leng D, Kong L, Dai Y, Xia Y. Intestinal interleukin-10 mobilization as a contributor to the anti-arthritis effect of orally administered madecassoside: a unique action mode of saponin compounds with poor bioavailability. Biochemical Pharmacology. 94: 30-8. PMID 25600909 DOI: 10.1016/j.bcp.2015.01.004  0.32
2015 Tong B, Dou Y, Wang T, Yu J, Wu X, Lu Q, Chou G, Wang Z, Kong L, Dai Y, Xia Y. Norisoboldine ameliorates collagen-induced arthritis through regulating the balance between Th17 and regulatory T cells in gut-associated lymphoid tissues. Toxicology and Applied Pharmacology. 282: 90-9. PMID 25481498 DOI: 10.1016/j.taap.2014.11.008  0.32
2015 Dou Y, Liu X, Yin Y, Han S, Lu Y, Liu Y, Hao D. Affinity chromatography revealed insights into unique functionality of two 14-3-3 protein species in developing maize kernels. Journal of Proteomics. 114: 274-86. PMID 25449830 DOI: 10.1016/j.jprot.2014.10.019  1
2015 Wang G, Xue Y, An L, Zheng Y, Dou Y, Zhang L, Liu Y. Theoretical study on the structural and antioxidant properties of some recently synthesised 2,4,5-trimethoxy chalcones. Food Chemistry. 171: 89-97. PMID 25308647 DOI: 10.1016/j.foodchem.2014.08.106  1
2015 Chen J, Dou Y, Wang Z, Li G. A novel method for PD feature extraction of power cable with renyi entropy Entropy. 17: 7698-7712. DOI: 10.3390/e17117698  0.32
2015 Dou Y, Zhang P, Ge B, Jiang J, Chen Y. An integrated technology pushing and requirement pulling model for weapon system portfolio selection in defence acquisition and manufacturing Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture. 229: 1046-1067. DOI: 10.1177/0954405414534640  0.32
2015 Peng J, He R, Tan M, Dou Y, Wang Z, Chen GZ, Jin X. Electrochemical preparation of fine powders of nickel-boron alloys in molten chlorides for magnetic hydrogenation catalysts Journal of the Electrochemical Society. 162: H271-H277. DOI: 10.1149/2.0871504jes  0.32
2015 Li Y, Li D, Qin X, Yang X, Liu Y, Zhang J, Dou Y, Song C, Xin H. Enhanced thermoelectric performance through carrier scattering at heterojunction potentials in BiSbTe based composites with Cu3SbSe4 nanoinclusions Journal of Materials Chemistry C. 3: 7045-7052. DOI: 10.1039/c5tc01318f  1
2015 Dou Y, Zhang X, Xu X, Zhou X, Han S, Wang R, Su M, Li X, Zhang J. Multiple noncovalent interactions mediated one-pot therapeutic assemblies for the effective treatment of atherosclerosis Journal of Materials Chemistry B. 3: 7355-7365. DOI: 10.1039/c5tb01474c  0.32
2015 Zhou X, Han S, Zhang Q, Dou Y, Guo J, Che L, Li X, Zhang J. A facile route to diverse assemblies by host-guest recognition Polymer Chemistry. 6: 3716-3727. DOI: 10.1039/c5py00297d  0.32
2015 Zhang J, Jin H, Chen Z, Cao M, Chen P, Dou Y, Zhao Y, Li J. Self-Assembling VO2 Nanonet with High Switching Performance at Wafer-Scale Chemistry of Materials. 27: 7419-7424. DOI: 10.1021/acs.chemmater.5b03314  0.32
2015 Dou Y, Liu Y. Computational investigation of lateral impact behavior of pressurized pipelines and influence of internal pressure Thin-Walled Structures. 95: 40-47. DOI: 10.1016/j.tws.2015.06.012  1
2015 Wang Y, Dou Y, Liu X, Lei Y. PR-ELM: Parallel regularized extreme learning machine based on cluster Neurocomputing. DOI: 10.1016/j.neucom.2015.08.066  0.32
2015 Xu SD, Fang CH, Tian GX, Chen Y, Dou YH, Kou JF, Wu XH. Reduction of 4-azidonaphthalimide with different phosphine ligands and exploration of their spectroscopic properties Journal of Molecular Structure. 1102: 197-202. DOI: 10.1016/j.molstruc.2015.08.056  0.32
2015 Wang J, Gao M, Wang D, Li X, Dou Y, Liu Y, Pan H. Chemical vapor deposition prepared bi-morphological carbon-coated Fe3O4 composites as anode materials for lithium-ion batteries Journal of Power Sources. 282: 257-264. DOI: 10.1016/j.jpowsour.2015.02.058  1
2015 Liu G, Zhang J, Dou Y. First-principles study of solute-solute binding in magnesium alloys Computational Materials Science. 103: 97-104. DOI: 10.1016/j.commatsci.2015.03.023  0.32
2015 Dou Y, Zhang J. Effects of structural relaxation on the generalized stacking fault energies of hexagonal-close-packed system from first-principles calculations Computational Materials Science. 98: 405-409. DOI: 10.1016/j.commatsci.2014.11.041  0.32
2015 Karatas H, Lee SY, Townsend EC, Cao F, Xu J, Bernard D, Liu L, Dou Y, Wang S. Structure-based design of conformationally constrained cyclic peptidomimetics to target the MLL1-WDR5 protein-protein interaction as inhibitors of the MLL1 methyltransferase activity Chinese Chemical Letters. 26: 455-458. DOI: 10.1016/j.cclet.2015.03.030  1
2015 Liu X, Wang L, Yin J, Dou Y, Zhang J. Absent multiple kernel learning Proceedings of the National Conference On Artificial Intelligence. 4: 2807-2813.  0.32
2014 Li M, Yang MH, Dou YQ, Liu Y. [Clinical research on supplementing Qi and activating blood circulation herbs on lung protection in acute lung injury ventilation patients]. Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials. 37: 2113-6. PMID 26027135  1
2014 Zheng J, Ma LT, Ren QY, Li L, Zhang Y, Shi HJ, Liu Y, Li CH, Dou YQ, Li SD, Zhang H, Yang MH. The influence of astragalus polysaccharide and β-elemene on LX-2 cell growth, apoptosis and activation. Bmc Gastroenterology. 14: 224. PMID 25551689 DOI: 10.1186/s12876-014-0224-8  1
2014 Komori H, Xiao Q, Janssens DH, Dou Y, Lee CY. Trithorax maintains the functional heterogeneity of neural stem cells through the transcription factor buttonhead. Elife. 3. PMID 25285447 DOI: 10.7554/eLife.03502  1
2014 Wu X, Yang Y, Dou Y, Ye J, Bian D, Wei Z, Tong B, Kong L, Xia Y, Dai Y. Arctigenin but not arctiin acts as the major effective constituent of Arctium lappa L. fruit for attenuating colonic inflammatory response induced by dextran sulfate sodium in mice. International Immunopharmacology. 23: 505-15. PMID 25284342 DOI: 10.1016/j.intimp.2014.09.026  0.32
2014 Yuan S, Tang H, Xing J, Fan X, Cai X, Li Q, Han P, Luo Y, Zhang Z, Jiang B, Dou Y, Gorospe M, Wang W. Methylation by NSun2 represses the levels and function of microRNA 125b. Molecular and Cellular Biology. 34: 3630-41. PMID 25047833 DOI: 10.1128/MCB.00243-14  1
2014 Benitah SA, Bracken A, Dou Y, Huangfu D, Ivanova N, Koseki H, Laurent L, Lim DA, Meshorer E, Pombo A, Sander M, Xu GL. Stem cell epigenetics: looking forward. Cell Stem Cell. 14: 706-9. PMID 25032261 DOI: 10.1016/j.stem.2014.05.011  1
2014 Wu L, Li L, Zhou B, Qin Z, Dou Y. H2B ubiquitylation promotes RNA Pol II processivity via PAF1 and pTEFb. Molecular Cell. 54: 920-31. PMID 24837678 DOI: 10.1016/j.molcel.2014.04.013  1
2014 Zhang J, Dou Y, Zhong Z, Su J, Xu D, Tang F, Zhang X, Zhao Y, Zeng X, Zhang F, You X. Clinical characteristics and therapy exploration of active human cytomegalovirus infection in 105 lupus patients. Lupus. 23: 889-897. PMID 24836584 DOI: 10.1177/0961203314532560  0.32
2014 Kryczek I, Lin Y, Nagarsheth N, Peng D, Zhao L, Zhao E, Vatan L, Szeliga W, Dou Y, Owens S, Zgodzinski W, Majewski M, Wallner G, Fang J, Huang E, et al. IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L. Immunity. 40: 772-84. PMID 24816405 DOI: 10.1016/j.immuni.2014.03.010  1
2014 Gao Z, Dou Y, Chen Y, Zheng Y. MicroRNA roles in the NF- κB signaling pathway during viral infections. Biomed Research International. 2014: 436097. PMID 24800225 DOI: 10.1155/2014/436097  0.32
2014 Su X, Zhu G, Ding X, Lee SY, Dou Y, Zhu B, Wu W, Li H. Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1. Genes & Development. 28: 622-36. PMID 24589551 DOI: 10.1101/gad.233239.113  1
2014 Cao F, Townsend EC, Karatas H, Xu J, Li L, Lee S, Liu L, Chen Y, Ouillette P, Zhu J, Hess JL, Atadja P, Lei M, Qin ZS, Malek S, ... ... Dou Y, et al. Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia. Molecular Cell. 53: 247-61. PMID 24389101 DOI: 10.1016/j.molcel.2013.12.001  1
2014 Xu F, Pang L, Cai X, Liu X, Yuan S, Fan X, Jiang B, Zhang X, Dou Y, Gorospe M, Wang W. let-7-repressesed Shc translation delays replicative senescence. Aging Cell. 13: 185-92. PMID 24165399 DOI: 10.1111/acel.12176  1
2013 Jiang H, Lu X, Shimada M, Dou Y, Tang Z, Roeder RG. Regulation of transcription by the MLL2 complex and MLL complex-associated AKAP95. Nature Structural & Molecular Biology. 20: 1156-63. PMID 23995757 DOI: 10.1038/nsmb.2656  1
2013 Wu L, Lee SY, Zhou B, Nguyen UT, Muir TW, Tan S, Dou Y. ASH2L regulates ubiquitylation signaling to MLL: trans-regulation of H3 K4 methylation in higher eukaryotes. Molecular Cell. 49: 1108-20. PMID 23453805 DOI: 10.1016/j.molcel.2013.01.033  1
2013 Pandey R, Dou Y. H2A.Z sets the stage in ESCs. Cell Stem Cell. 12: 143-4. PMID 23395439 DOI: 10.1016/j.stem.2013.01.012  1
2013 Karatas H, Townsend EC, Cao F, Chen Y, Bernard D, Liu L, Lei M, Dou Y, Wang S. High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction. Journal of the American Chemical Society. 135: 669-82. PMID 23210835 DOI: 10.1021/ja306028q  1
2013 Chen Z, Yan CT, Dou Y, Viboolsittiseri SS, Wang JH. The role of a newly identified SET domain-containing protein, SETD3, in oncogenesis. Haematologica. 98: 739-43. PMID 23065515 DOI: 10.3324/haematol.2012.066977  1
2012 Li X, Li L, Pandey R, Byun JS, Gardner K, Qin Z, Dou Y. The histone acetyltransferase MOF is a key regulator of the embryonic stem cell core transcriptional network. Cell Stem Cell. 11: 163-78. PMID 22862943 DOI: 10.1016/j.stem.2012.04.023  1
2012 Huang J, Wan B, Wu L, Yang Y, Dou Y, Lei M. Structural insight into the regulation of MOF in the male-specific lethal complex and the non-specific lethal complex. Cell Research. 22: 1078-81. PMID 22547026 DOI: 10.1038/cr.2012.72  1
2012 Chen Y, Cao F, Wan B, Dou Y, Lei M. Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30. Cell Research. 22: 598-602. PMID 22231628 DOI: 10.1038/cr.2012.9  1
2011 Katoh H, Qin ZS, Liu R, Wang L, Li W, Li X, Wu L, Du Z, Lyons R, Liu CG, Liu X, Dou Y, Zheng P, Liu Y. FOXP3 orchestrates H4K16 acetylation and H3K4 trimethylation for activation of multiple genes by recruiting MOF and causing displacement of PLU-1. Molecular Cell. 44: 770-84. PMID 22152480 DOI: 10.1016/j.molcel.2011.10.012  1
2011 Wu L, Zee BM, Wang Y, Garcia BA, Dou Y. The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation. Molecular Cell. 43: 132-44. PMID 21726816 DOI: 10.1016/j.molcel.2011.05.015  1
2011 Chen Y, Wan B, Wang KC, Cao F, Yang Y, Protacio A, Dou Y, Chang HY, Lei M. Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding. Embo Reports. 12: 797-803. PMID 21660059 DOI: 10.1038/embor.2011.101  1
2011 Ruthenburg AJ, Li H, Milne TA, Dewell S, McGinty RK, Yuen M, Ueberheide B, Dou Y, Muir TW, Patel DJ, Allis CD. Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions. Cell. 145: 692-706. PMID 21596426 DOI: 10.1016/j.cell.2011.03.053  1
2011 Carson WF, Cavassani KA, Dou Y, Kunkel SL. Epigenetic regulation of immune cell functions during post-septic immunosuppression. Epigenetics. 6: 273-83. PMID 21048427 DOI: 10.4161/epi.6.3.14017  1
2010 Cao F, Chen Y, Cierpicki T, Liu Y, Basrur V, Lei M, Dou Y. An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain. Plos One. 5: e14102. PMID 21124902 DOI: 10.1371/journal.pone.0014102  1
2010 Li X, Corsa CA, Pan PW, Wu L, Ferguson D, Yu X, Min J, Dou Y. MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1. Molecular and Cellular Biology. 30: 5335-47. PMID 20837706 DOI: 10.1128/MCB.00350-10  1
2010 Karatas H, Townsend EC, Bernard D, Dou Y, Wang S. Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1-WDR5 interaction. Journal of Medicinal Chemistry. 53: 5179-85. PMID 20575550 DOI: 10.1021/jm100139b  1
2010 Li X, Dou Y. New perspectives for the regulation of acetyltransferase MOF. Epigenetics. 5: 185-8. PMID 20305383 DOI: 10.4161/epi.5.3.11372  1
2010 Cavassani KA, Carson WF, Moreira AP, Wen H, Schaller MA, Ishii M, Lindell DM, Dou Y, Lukacs NW, Keshamouni VG, Hogaboam CM, Kunkel SL. The post sepsis-induced expansion and enhanced function of regulatory T cells create an environment to potentiate tumor growth. Blood. 115: 4403-11. PMID 20130237 DOI: 10.1182/blood-2009-09-241083  1
2010 Carson WF, Cavassani KA, Ito T, Schaller M, Ishii M, Dou Y, Kunkel SL. Impaired CD4+ T-cell proliferation and effector function correlates with repressive histone methylation events in a mouse model of severe sepsis. European Journal of Immunology. 40: 998-1010. PMID 20127677 DOI: 10.1002/eji.200939739  1
2009 Li X, Wu L, Corsa CA, Kunkel S, Dou Y. Two mammalian MOF complexes regulate transcription activation by distinct mechanisms. Molecular Cell. 36: 290-301. PMID 19854137 DOI: 10.1016/j.molcel.2009.07.031  1
2009 Ishii M, Wen H, Corsa CA, Liu T, Coelho AL, Allen RM, Carson WF, Cavassani KA, Li X, Lukacs NW, Hogaboam CM, Dou Y, Kunkel SL. Epigenetic regulation of the alternatively activated macrophage phenotype. Blood. 114: 3244-54. PMID 19567879 DOI: 10.1182/blood-2009-04-217620  1
2009 Cao F, Li X, Hiew S, Brady H, Liu Y, Dou Y. Dicer independent small RNAs associate with telomeric heterochromatin. Rna (New York, N.Y.). 15: 1274-81. PMID 19460867 DOI: 10.1261/rna.1423309  1
2009 Wu J, Huen MS, Lu LY, Ye L, Dou Y, Ljungman M, Chen J, Yu X. Histone ubiquitination associates with BRCA1-dependent DNA damage response. Molecular and Cellular Biology. 29: 849-60. PMID 19015238 DOI: 10.1128/MCB.01302-08  1
2008 Dou Y, Hess JL. Mechanisms of transcriptional regulation by MLL and its disruption in acute leukemia. International Journal of Hematology. 87: 10-8. PMID 18224408 DOI: 10.1007/s12185-007-0009-8  1
2008 Wen H, Dou Y, Hogaboam CM, Kunkel SL. Epigenetic regulation of dendritic cell-derived interleukin-12 facilitates immunosuppression after a severe innate immune response. Blood. 111: 1797-804. PMID 18055863 DOI: 10.1182/blood-2007-08-106443  1
2008 Wen H, Schaller MA, Dou Y, Hogaboam CM, Kunkel SL. Dendritic cells at the interface of innate and acquired immunity: the role for epigenetic changes. Journal of Leukocyte Biology. 83: 439-46. PMID 17991763 DOI: 10.1189/jlb.0607357  1
2007 Hyllus D, Stein C, Schnabel K, Schiltz E, Imhof A, Dou Y, Hsieh J, Bauer UM. PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation. Genes & Development. 21: 3369-80. PMID 18079182 DOI: 10.1101/gad.447007  1
2006 Lee S, Lee DK, Dou Y, Lee J, Lee B, Kwak E, Kong YY, Lee SK, Roeder RG, Lee JW. Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases. Proceedings of the National Academy of Sciences of the United States of America. 103: 15392-7. PMID 17021013 DOI: 10.1073/pnas.0607313103  1
2006 Dou Y, Milne TA, Ruthenburg AJ, Lee S, Lee JW, Verdine GL, Allis CD, Roeder RG. Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nature Structural & Molecular Biology. 13: 713-9. PMID 16878130 DOI: 10.1038/nsmb1128  1
2005 Milne TA, Dou Y, Martin ME, Brock HW, Roeder RG, Hess JL. MLL associates specifically with a subset of transcriptionally active target genes. Proceedings of the National Academy of Sciences of the United States of America. 102: 14765-70. PMID 16199523 DOI: 10.1073/pnas.0503630102  1
2005 Dou Y, Milne TA, Tackett AJ, Smith ER, Fukuda A, Wysocka J, Allis CD, Chait BT, Hess JL, Roeder RG. Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell. 121: 873-85. PMID 15960975 DOI: 10.1016/j.cell.2005.04.031  1
2005 Wysocka J, Swigut T, Milne TA, Dou Y, Zhang X, Burlingame AL, Roeder RG, Brivanlou AH, Allis CD. WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell. 121: 859-72. PMID 15960974 DOI: 10.1016/j.cell.2005.03.036  1
2005 Dou Y, Song X, Liu Y, Gorovsky MA. The H1 phosphorylation state regulates expression of CDC2 and other genes in response to starvation in Tetrahymena thermophila Molecular and Cellular Biology. 25: 3914-3922. PMID 15870266 DOI: 10.1128/MCB.25.10.3914-3922.2005  1
2005 Milne TA, Hughes CM, Lloyd R, Yang Z, Rozenblatt-Rosen O, Dou Y, Schnepp RW, Krankel C, Livolsi VA, Gibbs D, Hua X, Roeder RG, Meyerson M, Hess JL. Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 102: 749-54. PMID 15640349 DOI: 10.1073/pnas.0408836102  1
2004 Wang Y, Wysocka J, Sayegh J, Lee YH, Perlin JR, Leonelli L, Sonbuchner LS, McDonald CH, Cook RG, Dou Y, Roeder RG, Clarke S, Stallcup MR, Allis CD, Coonrod SA. Human PAD4 regulates histone arginine methylation levels via demethylimination. Science (New York, N.Y.). 306: 279-83. PMID 15345777 DOI: 10.1126/science.1101400  1
2002 Dou Y, Bowen J, Liu Y, Gorovsky MA. Phosphorylation and an ATP-dependent process increase the dynamic exchange of H1 in chromatin Journal of Cell Biology. 158: 1161-1170. PMID 12356861 DOI: 10.1083/jcb.200202131  1
2002 Dou Y, Gorovsky MA. Regulation of transcription by H1 phosphorylation in Tetrahymena is position independent and requires clustered sites Proceedings of the National Academy of Sciences of the United States of America. 99: 6142-6146. PMID 11972045 DOI: 10.1073/pnas.092029599  1
2000 Dou Y, Gorovsky MA. Phosphorylation of linker histone H1 regulates gene expression in vivo by creating a charge patch Molecular Cell. 6: 225-231. PMID 10983971  1
1999 Dou Y, Mizzen CA, Abrams M, Allis CD, Gorovsky MA. Phosphorylation of linker histone H1 regulates gene expression in vivo by mimicking H1 removal. Molecular Cell. 4: 641-7. PMID 10549296 DOI: 10.1016/S1097-2765(00)80215-4  1
1999 Mizzen CA, Dou Y, Liu Y, Cook RG, Gorovsky MA, Allis CD. Identification and mutation of phosphorylation sites in a linker histone. Phosphorylation of macronuclear H1 is not essential for viability in tetrahymena. The Journal of Biological Chemistry. 274: 14533-6. PMID 10329641 DOI: 10.1074/jbc.274.21.14533  1
1996 Dou Y, Tong T. Regulation of DNA replication initiation in eukaryotes Progress in Biochemistry and Biophysics. 23: 496-497.  1
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