Brian B. Tuch, Ph.D. - Publications

Biological and Medical Informatics University of California, San Francisco, San Francisco, CA 
Molecular Biology of Transcription Circuit Evolution, Candida albicans pathogenesis

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lowe E, Fan RA, Jiang J, Johnson HWB, Kirk CJ, McMinn D, Millare B, Muchamuel T, Qian Y, Tuch BB, Whang JA, Zuno P. Preclinical evaluation of KZR-261, a novel small molecule inhibitor of Sec61. Journal of Clinical Oncology. 38: 3582-3582. DOI: 10.1200/Jco.2020.38.15_Suppl.3582  0.313
2019 Cocco E, Schram AM, Kulick A, Misale S, Won HH, Yaeger R, Razavi P, Ptashkin R, Hechtman JF, Toska E, Cownie J, Somwar R, Shifman S, Mattar M, Selçuklu SD, ... ... Tuch BB, et al. Resistance to TRK inhibition mediated by convergent MAPK pathway activation. Nature Medicine. PMID 31406350 DOI: 10.1038/S41591-019-0542-Z  0.31
2019 Hong DS, Bauer TM, Lee JJ, Dowlati A, Brose MS, Farago AF, Taylor M, Shaw AT, Montez S, Meric-Bernstam F, Smith S, Tuch BB, Ebata K, Cruickshank S, Cox MC, et al. Larotrectinib in adult patients with solid tumours: a multicentre, open-label, phase I dose-escalation study. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 30624546 DOI: 10.1093/Annonc/Mdy539  0.347
2019 Lowe E, Fan AR, Jiang J, Johnson HWB, Kirk CJ, McMinn D, Muchamuel T, Qian Y, Tuch BB. Blocking Protein Secretion with Novel Small Molecule Inhibitors of Sec61 Represents a Potential Treatment Strategy Against Hematologic Malignancies Blood. 134: 408-408. DOI: 10.1182/Blood-2019-123782  0.315
2018 Laetsch TW, DuBois SG, Mascarenhas L, Turpin B, Federman N, Albert CM, Nagasubramanian R, Davis JL, Rudzinski E, Feraco AM, Tuch BB, Ebata KT, Reynolds M, Smith S, Cruickshank S, et al. Larotrectinib for paediatric solid tumours harbouring NTRK gene fusions: phase 1 results from a multicentre, open-label, phase 1/2 study. The Lancet. Oncology. PMID 29606586 DOI: 10.1016/S1470-2045(18)30119-0  0.302
2015 Sorrells TR, Booth LN, Tuch BB, Johnson AD. Intersecting transcription networks constrain gene regulatory evolution. Nature. 523: 361-5. PMID 26153861 DOI: 10.1038/Nature14613  0.796
2014 Enroth S, Andersson R, Bysani M, Wallerman O, Termén S, Tuch BB, De La Vega FM, Heldin CH, Moustakas A, Komorowski J, Wadelius C. Nucleosome regulatory dynamics in response to TGFβ. Nucleic Acids Research. 42: 6921-34. PMID 24771338 DOI: 10.1093/Nar/Gku326  0.487
2012 Nobile CJ, Fox EP, Nett JE, Sorrells TR, Mitrovich QM, Hernday AD, Tuch BB, Andes DR, Johnson AD. A recently evolved transcriptional network controls biofilm development in Candida albicans. Cell. 148: 126-38. PMID 22265407 DOI: 10.1016/J.Cell.2011.10.048  0.663
2012 Nobile CJ, Fox EP, Nett JE, Mitrovich QM, Hernday AD, Tuch BB, Andes DR, Johnson AD. The transcriptional network controlling biofilm development in Candida albicans F1000research. 3. DOI: 10.7490/F1000Research.1194.1  0.584
2011 Chen C, Pande K, French SD, Tuch BB, Noble SM. An iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis. Cell Host & Microbe. 10: 118-35. PMID 21843869 DOI: 10.1016/J.Chom.2011.07.005  0.357
2011 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA. Deterministic and stochastic allele specific gene expression in single mouse blastomeres. Plos One. 6: e21208. PMID 21731673 DOI: 10.1371/Journal.Pone.0021208  0.451
2011 Baker CR, Tuch BB, Johnson AD. Extensive DNA-binding specificity divergence of a conserved transcription regulator. Proceedings of the National Academy of Sciences of the United States of America. 108: 7493-8. PMID 21498688 DOI: 10.1073/Pnas.1019177108  0.658
2011 Graveley BR, Brooks AN, Carlson JW, Duff MO, Landolin JM, Yang L, Artieri CG, van Baren MJ, Boley N, Booth BW, Brown JB, Cherbas L, Davis CA, Dobin A, Li R, ... ... Tuch BB, et al. The developmental transcriptome of Drosophila melanogaster. Nature. 471: 473-9. PMID 21179090 DOI: 10.1038/Nature09715  0.431
2010 Booth LN, Tuch BB, Johnson AD. Intercalation of a new tier of transcription regulation into an ancient circuit. Nature. 468: 959-63. PMID 21164485 DOI: 10.1038/Nature09560  0.804
2010 Mitrovich QM, Tuch BB, De La Vega FM, Guthrie C, Johnson AD. Evolution of yeast noncoding RNAs reveals an alternative mechanism for widespread intron loss Science. 330: 838-841. PMID 21051641 DOI: 10.1126/Science.1194554  0.565
2010 Tuch BB, Mitrovich QM, Homann OR, Hernday AD, Monighetti CK, De La Vega FM, Johnson AD. The transcriptomes of two heritable cell types illuminate the circuit governing their differentiation. Plos Genetics. 6: e1001070. PMID 20808890 DOI: 10.1371/Journal.Pgen.1001070  0.68
2010 Tuch BB, Laborde RR, Xu X, Gu J, Chung CB, Monighetti CK, Stanley SJ, Olsen KD, Kasperbauer JL, Moore EJ, Broomer AJ, Tan R, Brzoska PM, Muller MW, Siddiqui AS, et al. Tumor transcriptome sequencing reveals allelic expression imbalances associated with copy number alterations. Plos One. 5: e9317. PMID 20174472 DOI: 10.1371/Journal.Pone.0009317  0.406
2010 Laborde RR, Tuch BB, Olsen KD, Kasperbauer JL, Moore EJ, Barker MA, Vega FMDL, Smith DI. Abstract 2957: Characterization of oral tumors by massively parallel ligation sequencing Cancer Research. 70: 2957-2957. DOI: 10.1158/1538-7445.Am10-2957  0.379
2009 Lao KQ, Tang F, Barbacioru C, Wang Y, Nordman E, Lee C, Xu N, Wang X, Tuch B, Bodeau J, Siddiqui A, Surani MA. mRNA-sequencing whole transcriptome analysis of a single cell on the solid™ system Journal of Biomolecular Techniques. 20: 266-271. PMID 19949700  0.313
2009 Holt LJ, Tuch BB, Villén J, Johnson AD, Gygi SP, Morgan DO. Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution. Science (New York, N.Y.). 325: 1682-6. PMID 19779198 DOI: 10.1126/Science.1172867  0.536
2009 Tang F, Barbacioru C, Wang Y, Nordman E, Lee C, Xu N, Wang X, Bodeau J, Tuch BB, Siddiqui A, Lao K, Surani MA. mRNA-Seq whole-transcriptome analysis of a single cell. Nature Methods. 6: 377-82. PMID 19349980 DOI: 10.1038/Nmeth.1315  0.472
2008 Tuch BB, Li H, Johnson AD. Evolution of eukaryotic transcription circuits. Science (New York, N.Y.). 319: 1797-9. PMID 18369141 DOI: 10.1126/Science.1152398  0.689
2008 Tuch BB, Galgoczy DJ, Hernday AD, Li H, Johnson AD. The evolution of combinatorial gene regulation in fungi. Plos Biology. 6: e38. PMID 18303948 DOI: 10.1371/Journal.Pbio.0060038  0.767
2007 Zordan RE, Miller MG, Galgoczy DJ, Tuch BB, Johnson AD. Interlocking transcriptional feedback loops control white-opaque switching in Candida albicans. Plos Biology. 5: e256. PMID 17880264 DOI: 10.1371/Journal.Pbio.0050256  0.647
2007 Mitrovich QM, Tuch BB, Guthrie C, Johnson AD. Computational and experimental approaches double the number of known introns in the pathogenic yeast Candida albicans. Genome Research. 17: 492-502. PMID 17351132 DOI: 10.1101/Gr.6111907  0.592
2006 Tsong AE, Tuch BB, Li H, Johnson AD. Evolution of alternative transcriptional circuits with identical logic. Nature. 443: 415-20. PMID 17006507 DOI: 10.1038/Nature05099  0.753
Show low-probability matches.