Marc L. Mendillo, Ph.D. - Publications

Affiliations: 
Biomedical Sciences University of California, San Diego, La Jolla, CA 
Area:
genetic recombination and DNA repair

15/42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 McGrail DJ, Li Y, Smith RS, Feng B, Dai H, Hu L, Dennehey B, Awasthi S, Mendillo ML, Sood AK, Mills GB, Lin SY, Yi SS, Sahni N. Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA-binding proteins. Cell Reports. Medicine. 101255. PMID 37909041 DOI: 10.1016/j.xcrm.2023.101255  0.382
2016 Chakrabortee S, Kayatekin C, Newby GA, Mendillo ML, Lancaster A, Lindquist S. Luminidependens (LD) is an Arabidopsis protein with prion behavior. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114519 DOI: 10.1073/Pnas.1604478113  0.322
2016 Scherz-Shouval R, Mendillo ML, Gaglia G, Ben-Aharon I, Beck AH, Whitesell L, Lindquist S. Abstract PR07: Mechanisms of stromal reprogramming mediated by heat shock factor 1 Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-Pr07  0.301
2015 Tsvetkov P, Mendillo ML, Zhao J, Carette JE, Merrill PH, Cikes D, Varadarajan M, van Diemen FR, Penninger JM, Goldberg AL, Brummelkamp TR, Santagata S, Lindquist S. Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome. Elife. 4. PMID 26327695 DOI: 10.7554/Elife.08467  0.323
2014 Filone CM, Caballero IS, Dower K, Mendillo ML, Cowley GS, Santagata S, Rozelle DK, Yen J, Rubins KH, Hacohen N, Root DE, Hensley LE, Connor J. The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infection. Plos Pathogens. 10: e1003904. PMID 24516381 DOI: 10.1371/Journal.Ppat.1003904  0.306
2013 Smith CE, Mendillo ML, Bowen N, Hombauer H, Campbell CS, Desai A, Putnam CD, Kolodner RD. Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway. Plos Genetics. 9: e1003869. PMID 24204293 DOI: 10.1371/Journal.Pgen.1003869  0.65
2013 Hura GL, Tsai CL, Claridge SA, Mendillo ML, Smith JM, Williams GJ, Mastroianni AJ, Alivisatos AP, Putnam CD, Kolodner RD, Tainer JA. DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals. Proceedings of the National Academy of Sciences of the United States of America. 110: 17308-13. PMID 24101514 DOI: 10.1073/Pnas.1308595110  0.688
2011 Mendillo M, Santagata S, Koeva M, Fraenkel E, Ince T, Whitesell L, Lindquist S. P3-01-09: Oncogenic Activation of HSF1 Enables the Malignant Progression of Breast Carcinoma. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P3-01-09  0.305
2010 Mendillo ML, Putnam CD, Mo AO, Jamison JW, Li S, Woods VL, Kolodner RD. Probing DNA- and ATP-mediated conformational changes in the MutS family of mispair recognition proteins using deuterium exchange mass spectrometry Journal of Biological Chemistry. 285: 13170-13182. PMID 20181951 DOI: 10.1074/Jbc.M110.108894  0.693
2009 Mendillo ML, Hargreaves VV, Jamison JW, Mo AO, Li S, Putnam CD, Woods VL, Kolodner RD. A conserved MutS homolog connector domain interface interacts with MutL homologs Proceedings of the National Academy of Sciences of the United States of America. 106: 22223-22228. PMID 20080788 DOI: 10.1073/Pnas.0912250106  0.665
2007 Kolodner RD, Mendillo ML, Putnam CD. Coupling distant sites in DNA during DNA mismatch repair Proceedings of the National Academy of Sciences of the United States of America. 104: 12953-12954. PMID 17664420 DOI: 10.1073/Pnas.0705698104  0.7
2007 Mendillo ML, Putnam CD, Kolodner RD. Escherichia coli MutS tetramerization domain structure reveals that stable dimers but not tetramers are essential for DNA mismatch repair in vivo Journal of Biological Chemistry. 282: 16345-16354. PMID 17426027 DOI: 10.1074/Jbc.M700858200  0.712
2006 Mazur DJ, Mendillo ML, Kolodner RD. Inhibition of Msh6 ATPase Activity by Mispaired DNA Induces a Msh2(ATP)-Msh6(ATP) State Capable of Hydrolysis-Independent Movement along DNA Molecular Cell. 22: 39-49. PMID 16600868 DOI: 10.1016/J.Molcel.2006.02.010  0.62
2006 Hess MT, Mendillo ML, Mazur DJ, Kolodner RD. Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene Proceedings of the National Academy of Sciences of the United States of America. 103: 558-563. PMID 16407100 DOI: 10.1073/Pnas.0510078103  0.596
2005 Mendillo ML, Mazur DJ, Kolodner RD. Analysis of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 complexes with DNA using a reversible DNA end-blocking system Journal of Biological Chemistry. 280: 22245-22257. PMID 15811858 DOI: 10.1074/Jbc.M407545200  0.637
Low-probability matches (unlikely to be authored by this person)
2020 Zhou Y, Han C, Wang E, Lorch AH, Serafin V, Cho BK, Guttierrez Diaz BT, Calvo J, Fang C, Khodadadi-Jamayran A, Tabaglio T, Marier C, Kuchmiy A, Sun L, Yacu G, ... ... Mendillo ML, et al. Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia. Cancer Discovery. PMID 32444465 DOI: 10.1158/2159-8290.Cd-19-1436  0.299
2017 Park J, Yang J, Wenzel AT, Ramachandran A, Lee WJ, Daniels JC, Kim J, Martinez-Escala E, Amankulor N, Pro B, Guitart J, Mendillo ML, Savas JN, Boggon TJ, Choi J. Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E). Blood. PMID 28694326 DOI: 10.1182/Blood-2017-02-768234  0.292
2013 Santagata S, Mendillo ML, Tang YC, Subramanian A, Perley CC, Roche SP, Wong B, Narayan R, Kwon H, Koeva M, Amon A, Golub TR, Porco JA, Whitesell L, Lindquist S. Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state. Science (New York, N.Y.). 341: 1238303. PMID 23869022 DOI: 10.1126/Science.1238303  0.291
2020 Alasady MJ, Mendillo ML. The Multifaceted Role of HSF1 in Tumorigenesis. Advances in Experimental Medicine and Biology. 1243: 69-85. PMID 32297212 DOI: 10.1007/978-3-030-40204-4_5  0.284
2014 Petrocca F, Altschuler G, Tan SM, Mendillo ML, Yan H, Jerry DJ, Kung AL, Hide W, Ince TA, Lieberman J. Abstract SY43-03: Screening for triple negative breast cancer vulnerabilities Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Sy43-03  0.278
2012 Mendillo ML, Santagata S, Koeva M, Bell GW, Hu R, Tamimi RM, Fraenkel E, Ince TA, Whitesell L, Lindquist S. HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers. Cell. 150: 549-62. PMID 22863008 DOI: 10.1016/J.Cell.2012.06.031  0.276
2014 Scherz-Shouval R, Santagata S, Mendillo ML, Sholl LM, Ben-Aharon I, Beck AH, Dias-Santagata D, Koeva M, Stemmer SM, Whitesell L, Lindquist S. The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy. Cell. 158: 564-78. PMID 25083868 DOI: 10.1016/J.Cell.2014.05.045  0.273
2014 Whitesell L, Santagata S, Mendillo ML, Lin NU, Proia DA, Lindquist S. HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models. Proceedings of the National Academy of Sciences of the United States of America. 111: 18297-302. PMID 25489079 DOI: 10.1073/Pnas.1421323111  0.272
2013 Petrocca F, Altschuler G, Tan SM, Mendillo ML, Yan H, Jerry DJ, Kung AL, Hide W, Ince TA, Lieberman J. A genome-wide siRNA screen identifies proteasome addiction as a vulnerability of basal-like triple-negative breast cancer cells. Cancer Cell. 24: 182-96. PMID 23948298 DOI: 10.1016/J.Ccr.2013.07.008  0.268
2011 Santagata S, Hu R, Lin N, Mendillo M, Collins L, Hankinson S, Schnitt S, Whitesell L, Lindquist S, Tamimi R, Ince T. P5-01-13: High Levels of Nuclear Heat Shock Factor 1 (HSF1) Are Associated with Poor Prognosis in Breast Cancer: Results from the Nurses' Health Study. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P5-01-13  0.267
2011 Santagata S, Hu R, Lin NU, Mendillo ML, Collins LC, Hankinson SE, Schnitt SJ, Whitesell L, Tamimi RM, Lindquist S, Ince TA. High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 108: 18378-83. PMID 22042860 DOI: 10.1073/Pnas.1115031108  0.262
2015 Tsvetkov P, Mendillo ML, Zhao J, Carette JE, Merrill PH, Cikes D, Varadarajan M, Diemen FRv, Penninger JM, Goldberg AL, Brummelkamp TR, Santagata S, Lindquist S. Author response: Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome Elife. DOI: 10.7554/Elife.08467.021  0.259
2023 Amici DR, Cingoz H, Alasady MJ, Alhayek S, Phoumyvong CM, Sahni N, Yi SS, Mendillo ML. The HAPSTR2 retrogene buffers stress signaling and resilience in mammals. Nature Communications. 14: 152. PMID 36631436 DOI: 10.1038/s41467-022-35697-1  0.248
2023 Li Y, Dobrolecki LE, Sallas C, Zhang X, Kerr TD, Bisht D, Wang Y, Awasthi S, Kaundal B, Wu S, Peng W, Mendillo ML, Lu Y, Jeter CR, Peng G, et al. PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition. Cell Reports. Medicine. 4: 101326. PMID 38118413 DOI: 10.1016/j.xcrm.2023.101326  0.244
1999 Blumenfeld A, Slaugenhaupt SA, Liebert CB, Temper V, Maayan C, Gill S, Lucente DE, Idelson M, MacCormack K, Monahan MA, Mull J, Leyne M, Mendillo M, Schiripo T, Mishori E, et al. Precise genetic mapping and haplotype analysis of the familial dysautonomia gene on human chromosome 9q31. American Journal of Human Genetics. 64: 1110-8. PMID 10090896 DOI: 10.1086/302339  0.218
2022 Hua X, Li Y, Pentaparthi SR, McGrail DJ, Zou R, Guo L, Shrawat A, Cirillo KM, Li Q, Bhat AV, Xu M, Qi D, Singh A, McGrath F, Andrews SB, ... ... Mendillo ML, et al. Landscape of microRNA regulatory network architecture and functional rerouting in cancer. Cancer Research. PMID 36265133 DOI: 10.1158/0008-5472.CAN-20-0371  0.201
2022 Amici DR, Ansel DJ, Metz KA, Smith RS, Phoumyvong CM, Gayatri S, Chamera T, Edwards SL, O'Hara BP, Srivastava S, Brockway S, Takagishi SR, Cho BK, Goo YA, Kelleher NL, ... ... Mendillo ML, et al. C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways. Proceedings of the National Academy of Sciences of the United States of America. 119: e2111262119. PMID 35776542 DOI: 10.1073/pnas.2111262119  0.161
2022 Smith RS, Takagishi SR, Amici DR, Metz K, Gayatri S, Alasady MJ, Wu Y, Brockway S, Taiberg SL, Khalatyan N, Taipale M, Santagata S, Whitesell L, Lindquist S, Savas JN, ... Mendillo ML, et al. HSF2 cooperates with HSF1 to drive a transcriptional program critical for the malignant state. Science Advances. 8: eabj6526. PMID 35294249 DOI: 10.1126/sciadv.abj6526  0.153
2024 Mayer MP, Blair L, Blatch GL, Borges TJ, Chadli A, Chiosis G, de Thonel A, Dinkova-Kostova A, Ecroyd H, Edkins AL, Eguchi T, Fleshner M, Foley KP, Fragkostefanakis S, Gestwicki J, ... ... Mendillo ML, et al. Stress Biology: Complexity and Multifariousness in Health and Disease. Cell Stress & Chaperones. PMID 38311120 DOI: 10.1016/j.cstres.2024.01.006  0.139
2024 Amici DR, Alhayek S, Klein AT, Wang YZ, Wilen AP, Song W, Zhu P, Thakkar A, King MA, Steffeck AW, Alasady MJ, Peek C, Savas JN, Mendillo ML. Tight regulation of a nuclear HAPSTR1-HUWE1 pathway essential for mammalian life. Life Science Alliance. 7. PMID 38453366 DOI: 10.26508/lsa.202302370  0.128
2021 Kunder R, Velyunskiy M, Dunne SF, Cho BK, Kanojia D, Begg L, Orriols AM, Fleming-Trujillo E, Vadlamani P, Vialichka A, Bolin R, Perrino JN, Roth D, Clutter MR, Zielinski-Mozny NA, ... ... Mendillo ML, et al. Synergistic PIM kinase and proteasome inhibition as a therapeutic strategy for MYC-overexpressing triple-negative breast cancer. Cell Chemical Biology. PMID 34525344 DOI: 10.1016/j.chembiol.2021.08.011  0.125
2022 Ali ES, Lipońska A, O'Hara BP, Amici DR, Torno MD, Gao P, Asara JM, Yap MF, Mendillo ML, Ben-Sahra I. The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis. Molecular Cell. PMID 35772404 DOI: 10.1016/j.molcel.2022.06.008  0.123
2020 Brockway S, Wang G, Jackson JM, Amici DR, Takagishi SR, Clutter MR, Bartom ET, Mendillo ML. Quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq. Nature Communications. 11: 5722. PMID 33184288 DOI: 10.1038/s41467-020-19553-8  0.122
2023 Klein AT, Mendillo ML. Addicted to proteostasis: How KRAS-driven cancers acquire resistance to clinical KRAS inhibitors. Cell Chemical Biology. 30: 1334-1336. PMID 37977128 DOI: 10.1016/j.chembiol.2023.10.007  0.11
2021 Amici DR, Jackson JM, Truica MI, Smith RS, Abdulkadir SA, Mendillo ML. FIREWORKS: a bottom-up approach to integrative coessentiality network analysis. Life Science Alliance. 4. PMID 33328249 DOI: 10.26508/lsa.202000882  0.108
2023 Shum A, Zaichick S, McElroy GS, D'Alessandro K, Alasady MJ, Novakovic M, Peng W, Grebenik EA, Chung D, Flanagan ME, Smith R, Morales A, Stumpf L, McGrath K, Krainc D, ... Mendillo ML, et al. Octopamine metabolically reprograms astrocytes to confer neuroprotection against α-synuclein. Proceedings of the National Academy of Sciences of the United States of America. 120: e2217396120. PMID 37068235 DOI: 10.1073/pnas.2217396120  0.093
2021 Amici DR, Pinal-Fernandez I, Christopher-Stine L, Mammen AL, Mendillo ML. A network of core and subtype-specific gene expression programs in myositis. Acta Neuropathologica. PMID 34499219 DOI: 10.1007/s00401-021-02365-5  0.086
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