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J. Christopher C. Love - Publications

Chemical Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
Nano-based Drugs, Personalized Medicine, Cancer Immunology

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Liao MC, Muratore CR, Gierahn TM, Sullivan SE, Srikanth P, De Jager PL, Love JC, Young-Pearse TL. Single-Cell Detection of Secreted Aβ and sAPPα from Human IPSC-Derived Neurons and Astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1730-46. PMID 26843653 DOI: 10.1523/Jneurosci.2735-15.2016  0.88
2015 Ozkumur AY, Goods BA, Love JC. Development of a High-Throughput Functional Screen Using Nanowell-Assisted Cell Patterning. Small (Weinheim An Der Bergstrasse, Germany). 11: 4643-50. PMID 26121321 DOI: 10.1002/smll.201500674  0.88
2015 Mozdzierz NJ, Love KR, Lee KS, Lee HL, Shah KA, Ram RJ, Love JC. A perfusion-capable microfluidic bioreactor for assessing microbial heterologous protein production. Lab On a Chip. 15: 2918-22. PMID 26055071 DOI: 10.1039/c5lc00443h  0.88
2015 Shah KA, Clark JJ, Goods BA, Politano TJ, Mozdzierz NJ, Zimnisky RM, Leeson RL, Love C, Love KR. Automated pipeline for rapid production & screening of HIV-specific monoclonal antibodies using Pichia pastoris. Biotechnology and Bioengineering. PMID 26032261 DOI: 10.1002/bit.25663  0.88
2015 Patil SU, Ogunniyi AO, Calatroni A, Tadigotla VR, Ruiter B, Ma A, Moon J, Love JC, Shreffler WG. Peanut oral immunotherapy transiently expands circulating Ara h 2-specific B cells with a homologous repertoire in unrelated subjects. The Journal of Allergy and Clinical Immunology. 136: 125-134.e12. PMID 25985925 DOI: 10.1016/j.jaci.2015.03.026  0.88
2015 Cao Y, Goods BA, Raddassi K, Nepom GT, Kwok WW, Love JC, Hafler DA. Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis. Science Translational Medicine. 7: 287ra74. PMID 25972006 DOI: 10.1126/Scitranslmed.Aaa8038  0.88
2015 Zhang CZ, Adalsteinsson VA, Francis J, Cornils H, Jung J, Maire C, Ligon KL, Meyerson M, Love JC. Calibrating genomic and allelic coverage bias in single-cell sequencing. Nature Communications. 6: 6822. PMID 25879913 DOI: 10.1038/Ncomms7822  0.88
2015 Castellarnau M, Szeto GL, Su HW, Tokatlian T, Love JC, Irvine DJ, Voldman J. Stochastic particle barcoding for single-cell tracking and multiparametric analysis. Small (Weinheim An Der Bergstrasse, Germany). 11: 489-98. PMID 25180800 DOI: 10.1002/Smll.201401369  0.88
2014 Torres AJ, Hill AS, Love JC. Nanowell-based immunoassays for measuring single-cell secretion: characterization of transport and surface binding. Analytical Chemistry. 86: 11562-9. PMID 25347613 DOI: 10.1021/ac4030297  0.88
2014 Yao X, Williamson C, Adalsteinsson VA, D'Agostino RS, Fitton T, Smaroff GG, William RT, Wittrup KD, Love JC. Tumor cells are dislodged into the pulmonary vein during lobectomy. The Journal of Thoracic and Cardiovascular Surgery. 148: 3224-31.e1-5. PMID 25172322 DOI: 10.1016/J.Jtcvs.2014.06.074  0.88
2014 Tsioris K, Torres AJ, Douce TB, Love JC. A new toolbox for assessing single cells. Annual Review of Chemical and Biomolecular Engineering. 5: 455-77. PMID 24910919 DOI: 10.1146/annurev-chembioeng-060713-035958  0.88
2014 Francis JM, Zhang CZ, Maire CL, Jung J, Manzo VE, Adalsteinsson VA, Homer H, Haidar S, Blumenstiel B, Pedamallu CS, Ligon AH, Love JC, Meyerson M, Ligon KL. EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing. Cancer Discovery. 4: 956-71. PMID 24893890 DOI: 10.1158/2159-8290.CD-13-0879  0.88
2014 Adalsteinsson VA, Love JC. Towards Engineered Processes for Sequencing-Based Analysis of Single Circulating Tumor Cells. Current Opinion in Chemical Engineering. 4: 97-104. PMID 24839591 DOI: 10.1016/j.coche.2014.01.011  0.88
2014 Lohr JG, Adalsteinsson VA, Cibulskis K, Choudhury AD, Rosenberg M, Cruz-Gordillo P, Francis JM, Zhang CZ, Shalek AK, Satija R, Trombetta JJ, Lu D, Tallapragada N, Tahirova N, Kim S, ... ... Love JC, et al. Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer. Nature Biotechnology. 32: 479-84. PMID 24752078 DOI: 10.1038/Nbt.2892  0.88
2014 Ogunniyi AO, Thomas BA, Politano TJ, Varadarajan N, Landais E, Poignard P, Walker BD, Kwon DS, Love JC. Profiling human antibody responses by integrated single-cell analysis. Vaccine. 32: 2866-73. PMID 24602776 DOI: 10.1016/J.Vaccine.2014.02.020  0.88
2014 Yao X, Choudhury AD, Yamanaka YJ, Adalsteinsson VA, Gierahn TM, Williamson CA, Lamb CR, Taplin ME, Nakabayashi M, Chabot MS, Li T, Lee GS, Boehm JS, Kantoff PW, Hahn WC, ... ... Love JC, et al. Functional analysis of single cells identifies a rare subset of circulating tumor cells with malignant traits. Integrative Biology : Quantitative Biosciences From Nano to Macro. 6: 388-98. PMID 24522233 DOI: 10.1039/C3Ib40264A  0.88
2014 Zhou P, Shaffer DR, Alvarez Arias DA, Nakazaki Y, Pos W, Torres AJ, Cremasco V, Dougan SK, Cowley GS, Elpek K, Brogdon J, Lamb J, Turley SJ, Ploegh HL, Root DE, ... Love JC, et al. In vivo discovery of immunotherapy targets in the tumour microenvironment. Nature. 506: 52-7. PMID 24476824 DOI: 10.1038/Nature12988  0.88
2014 Chattopadhyay PK, Gierahn TM, Roederer M, Love JC. Single-cell technologies for monitoring immune systems. Nature Immunology. 15: 128-35. PMID 24448570 DOI: 10.1038/ni.2796  0.88
2014 Gierahn TM, Loginov D, Love JC. Crossword: a fully automated algorithm for the segmentation and quality control of protein microarray images. Journal of Proteome Research. 13: 362-71. PMID 24417579 DOI: 10.1021/pr401167h  0.88
2013 Adalsteinsson VA, Tahirova N, Tallapragada N, Yao X, Campion L, Angelini A, Douce TB, Huang C, Bowman B, Williamson CA, Kwon DS, Wittrup KD, Love JC. Single cells from human primary colorectal tumors exhibit polyfunctional heterogeneity in secretions of ELR+ CXC chemokines. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 1272-81. PMID 23995780 DOI: 10.1039/C3Ib40059J  0.88
2013 Reuel NF, Grassbaugh B, Kruss S, Mundy JZ, Opel C, Ogunniyi AO, Egodage K, Wahl R, Helk B, Zhang J, Kalcioglu ZI, Tvrdy K, Bellisario DO, Mu B, Blake SS, ... ... Love JC, et al. Emergent properties of nanosensor arrays: applications for monitoring IgG affinity distributions, weakly affined hypermannosylation, and colony selection for biomanufacturing. Acs Nano. 7: 7472-82. PMID 23909808 DOI: 10.1021/Nn403215E  0.88
2013 Love KR, Bagh S, Choi J, Love JC. Microtools for single-cell analysis in biopharmaceutical development and manufacturing. Trends in Biotechnology. 31: 280-6. PMID 23582471 DOI: 10.1016/J.Tibtech.2013.03.001  0.88
2013 Nguyen CQ, Ogunniyi AO, Karabiyik A, Love JC. Single-cell analysis reveals isotype-specific autoreactive B cell repertoires in Sjögren's syndrome. Plos One. 8: e58127. PMID 23516437 DOI: 10.1371/journal.pone.0058127  0.88
2013 Yamanaka YJ, Gierahn TM, Love JC. The dynamic lives of T cells: new approaches and themes. Trends in Immunology. 34: 59-66. PMID 23200626 DOI: 10.1016/  0.88
2013 Torres AJ, Contento RL, Gordo S, Wucherpfennig KW, Love JC. Functional single-cell analysis of T-cell activation by supported lipid bilayer-tethered ligands on arrays of nanowells. Lab On a Chip. 13: 90-9. PMID 23070211 DOI: 10.1039/C2Lc40869D  0.88
2013 Love JC, Love KR, Barone PW. Enabling global access to high-quality biopharmaceuticals Current Opinion in Chemical Engineering. 2: 383-390. DOI: 10.1016/j.coche.2013.09.002  0.88
2013 Lam LKW, Maire C, Francis J, Ligon KL, Meyerson ML, Adalsteinsson V, Love JC. A single-cell perspective on signaling and heterogeneity maintenance in glioblastoma multiforme Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 165-166.  0.88
2013 Castellarnau M, Szeto GL, Irvine DJ, Love JC, Voldman J. Stochastic barcoding for single-cell tracking 17th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2013. 1: 690-692.  0.88
2012 Yamanaka YJ, Szeto GL, Gierahn TM, Forcier TL, Benedict KF, Brefo MS, Lauffenburger DA, Irvine DJ, Love JC. Cellular barcodes for efficiently profiling single-cell secretory responses by microengraving. Analytical Chemistry. 84: 10531-6. PMID 23205933 DOI: 10.1021/Ac302264Q  0.88
2012 Yamanaka YJ, Berger CT, Sips M, Cheney PC, Alter G, Love JC. Single-cell analysis of the dynamics and functional outcomes of interactions between human natural killer cells and target cells. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 1175-84. PMID 22945136 DOI: 10.1039/c2ib20167d  0.88
2012 Love KR, Politano TJ, Panagiotou V, Jiang B, Stadheim TA, Love JC. Systematic single-cell analysis of Pichia pastoris reveals secretory capacity limits productivity. Plos One. 7: e37915. PMID 22685548 DOI: 10.1371/journal.pone.0037915  1
2012 Varadarajan N, Kwon DS, Law KM, Ogunniyi AO, Anahtar MN, Richter JM, Walker BD, Love JC. Rapid, efficient functional characterization and recovery of HIV-specific human CD8+ T cells using microengraving. Proceedings of the National Academy of Sciences of the United States of America. 109: 3885-90. PMID 22355106 DOI: 10.1073/Pnas.1111205109  0.88
2012 Yalçın A, Yamanaka YJ, Love JC. Analytical technologies for integrated single-cell analysis of human immune responses. Methods in Molecular Biology (Clifton, N.J.). 853: 211-35. PMID 22323150 DOI: 10.1007/978-1-61779-567-1_16  0.88
2012 Han Q, Bagheri N, Bradshaw EM, Hafler DA, Lauffenburger DA, Love JC. Polyfunctional responses by human T cells result from sequential release of cytokines. Proceedings of the National Academy of Sciences of the United States of America. 109: 1607-12. PMID 22160692 DOI: 10.1073/Pnas.1117194109  1
2012 Srinivas RL, Shasha D, Han Q, Chapin SC, Walker BD, Love JC, Doyle PS. Encoded gel particle array for rapid, multiplexed protein detection in complex media Proceedings of the 16th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2012. 377-379.  0.88
2011 Varadarajan N, Julg B, Yamanaka YJ, Chen H, Ogunniyi AO, McAndrew E, Porter LC, Piechocka-Trocha A, Hill BJ, Douek DC, Pereyra F, Walker BD, Love JC. A high-throughput single-cell analysis of human CD8⁺ T cell functions reveals discordance for cytokine secretion and cytolysis. The Journal of Clinical Investigation. 121: 4322-31. PMID 21965332 DOI: 10.1172/Jci58653  1
2011 Choi J, Love KR, Gong Y, Gierahn TM, Love JC. Immuno-hybridization chain reaction for enhancing detection of individual cytokine-secreting human peripheral mononuclear cells. Analytical Chemistry. 83: 6890-5. PMID 21812465 DOI: 10.1021/Ac2013916  1
2011 Zhao W, Schafer S, Choi J, Yamanaka YJ, Lombardi ML, Bose S, Carlson AL, Phillips JA, Teo W, Droujinine IA, Cui CH, Jain RK, Lammerding J, Love JC, Lin CP, et al. Cell-surface sensors for real-time probing of cellular environments. Nature Nanotechnology. 6: 524-31. PMID 21765401 DOI: 10.1038/Nnano.2011.101  1
2011 Panagiotou V, Love KR, Jiang B, Nett J, Stadheim T, Love JC. Generation and screening of Pichia pastoris strains with enhanced protein production by use of microengraving. Applied and Environmental Microbiology. 77: 3154-6. PMID 21378037 DOI: 10.1128/AEM.00104-11  1
2010 Love JC. Making antibodies from scratch. Nature Biotechnology. 28: 1176-8. PMID 21057486 DOI: 10.1038/nbt1110-1176  1
2010 Gong Y, Ogunniyi AO, Love JC. Massively parallel detection of gene expression in single cells using subnanolitre wells. Lab On a Chip. 10: 2334-7. PMID 20686711 DOI: 10.1039/c004847j  1
2010 Han Q, Bradshaw EM, Nilsson B, Hafler DA, Love JC. Multidimensional analysis of the frequencies and rates of cytokine secretion from single cells by quantitative microengraving. Lab On a Chip. 10: 1391-400. PMID 20376398 DOI: 10.1039/B926849A  1
2010 Love KR, Panagiotou V, Jiang B, Stadheim TA, Love JC. Integrated single-cell analysis shows Pichia pastoris secretes protein stochastically. Biotechnology and Bioengineering. 106: 319-25. PMID 20148400 DOI: 10.1002/bit.22688  1
2010 Choi JH, Ogunniyi AO, Du M, Du M, Kretschmann M, Eberhardt J, Love JC. Development and optimization of a process for automated recovery of single cells identified by microengraving. Biotechnology Progress. 26: 888-95. PMID 20063389 DOI: 10.1002/btpr.374  1
2010 Song Q, Han Q, Bradshaw EM, Kent SC, Raddassi K, Nilsson B, Nepom GT, Hafler DA, Love JC. On-chip activation and subsequent detection of individual antigen-specific T cells. Analytical Chemistry. 82: 473-7. PMID 20000848 DOI: 10.1021/Ac9024363  1
2010 Love JC. Integrated process design for single-cell analytical technologies Aiche Journal. 56: 2496-2502. DOI: 10.1002/aic.12413  1
2009 Ogunniyi AO, Story CM, Papa E, Guillen E, Love JC. Screening individual hybridomas by microengraving to discover monoclonal antibodies. Nature Protocols. 4: 767-82. PMID 19528952 DOI: 10.1038/nprot.2009.40  1
2009 Hu CC, Dougan SK, McGehee AM, Love JC, Ploegh HL. XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells. The Embo Journal. 28: 1624-36. PMID 19407814 DOI: 10.1038/Emboj.2009.117  1
2009 Ronan JL, Story CM, Papa E, Love JC. Optimization of the surfaces used to capture antibodies from single hybridomas reduces the time required for microengraving. Journal of Immunological Methods. 340: 164-9. PMID 19028499 DOI: 10.1016/j.jim.2008.10.018  1
2008 Story CM, Papa E, Hu CC, Ronan JL, Herlihy K, Ploegh HL, Love JC. Profiling antibody responses by multiparametric analysis of primary B cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 17902-7. PMID 19004776 DOI: 10.1073/Pnas.0805470105  1
2008 Bradshaw EM, Kent SC, Tripuraneni V, Orban T, Ploegh HL, Hafler DA, Love JC. Concurrent detection of secreted products from human lymphocytes by microengraving: cytokines and antigen-reactive antibodies. Clinical Immunology (Orlando, Fla.). 129: 10-8. PMID 18675591 DOI: 10.1016/J.Clim.2008.06.009  1
2008 Perez-Castillejos R, Wong AP, Love JC, Whitesides GM. PARTition of microchannels with collagen for fabricating tunable 3D cellular microenvironments 12th International Conference On Miniaturized Systems For Chemistry and Life Sciences - the Proceedings of Microtas 2008 Conference. 1217-1219.  0.88
2007 Leduc PR, Wong MS, Ferreira PM, Groff RE, Haslinger K, Koonce MP, Lee WY, Love JC, McCammon JA, Monteiro-Riviere NA, Rotello VM, Rubloff GW, Westervelt R, Yoda M. Towards an in vivo biologically inspired nanofactory. Nature Nanotechnology. 2: 3-7. PMID 18654192 DOI: 10.1038/Nnano.2006.180  1
2007 Vyas JM, Kim YM, Artavanis-Tsakonas K, Love JC, Van der Veen AG, Ploegh HL. Tubulation of class II MHC compartments is microtubule dependent and involves multiple endolysosomal membrane proteins in primary dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 7199-210. PMID 17513769 DOI: 10.4049/Jimmunol.178.11.7199  1
2006 Artavanis-Tsakonas K, Love JC, Ploegh HL, Vyas JM. Recruitment of CD63 to Cryptococcus neoformans phagosomes requires acidification. Proceedings of the National Academy of Sciences of the United States of America. 103: 15945-50. PMID 17043215 DOI: 10.1073/Pnas.0607528103  1
2006 Love JC, Ronan JL, Grotenbreg GM, van der Veen AG, Ploegh HL. A microengraving method for rapid selection of single cells producing antigen-specific antibodies. Nature Biotechnology. 24: 703-7. PMID 16699501 DOI: 10.1038/Nbt1210  1
2005 Whitesides GM, Kriebel JK, Love JC. Molecular engineering of surfaces using self-assembled monolayers. Science Progress. 88: 17-48. PMID 16372593 DOI: 10.3184/003685005783238462  1
2005 Love JC, Estroff LA, Kriebel JK, Nuzzo RG, Whitesides GM. Self-assembled monolayers of thiolates on metals as a form of nanotechnology. Chemical Reviews. 105: 1103-69. PMID 15826011 DOI: 10.1021/Cr0300789  1
2004 Hu S, Eberhard L, Chen J, Love JC, Butler JP, Fredberg JJ, Whitesides GM, Wang N. Mechanical anisotropy of adherent cells probed by a three-dimensional magnetic twisting device. American Journal of Physiology. Cell Physiology. 287: C1184-91. PMID 15213058 DOI: 10.1152/ajpcell.00224.2004  1
2004 Gates BD, Xu Q, Love JC, Wolfe DB, Whitesides GM. Unconventional nanofabrication Annual Review of Materials Research. 34: 339-372. DOI: 10.1146/annurev.matsci.34.052803.091100  1
2004 Xu Q, Tonks I, Fuerstman MJ, Love JC, Whitesides GM. Fabrication of free-standing metallic pyramidal shells Nano Letters. 4: 2509-2511. DOI: 10.1021/Nl0484797  1
2004 Wolfe DB, Love JC, Gates BD, Whitesides GM, Conroy RS, Prentiss M. Fabrication of planar optical waveguides by electrical microcontact printing Applied Physics Letters. 84: 1623-1625.  1
2003 Urbach AR, Love JC, Prentiss MG, Whitesides GM. Sub-100 nm confinement of magnetic nanoparticles using localized magnetic field gradients. Journal of the American Chemical Society. 125: 12704-5. PMID 14558807 DOI: 10.1021/ja0378308  1
2003 Love JC, Urbach AR, Prentiss MG, Whitesides GM. Three-dimensional self-assembly of metallic rods with submicron diameters using magnetic interactions. Journal of the American Chemical Society. 125: 12696-7. PMID 14558803 DOI: 10.1021/Ja037642H  1
2003 Love JC, Wolfe DB, Haasch R, Chabinyc ML, Paul KE, Whitesides GM, Nuzzo RG. Formation and structure of self-assembled monolayers of alkanethiolates on palladium. Journal of the American Chemical Society. 125: 2597-609. PMID 12603148 DOI: 10.1021/Ja028692+  1
2003 Chabinyc ML, Love JC, Thywissen JH, Cervelli F, Prentiss MG, Whitesides GM. Self-assembled monolayers exposed to metastable argon beams undergo thiol exchange reactions Langmuir. 19: 2201-2205. DOI: 10.1021/La026495I  1
2002 Odom TW, Thalladi VR, Love JC, Whitesides GM. Generation of 30-50 nm structures using easily fabricated, composite PDMS masks. Journal of the American Chemical Society. 124: 12112-3. PMID 12371848 DOI: 10.1021/Ja0209464  1
2002 Love JC, Wolfe DB, Chabinyc ML, Paul KE, Whitesides GM. Self-assembled monolayers of alkanethiolates on palladium are good etch resists. Journal of the American Chemical Society. 124: 1576-7. PMID 11853422 DOI: 10.1021/Ja012569L  1
2002 Wolfe DB, Love JC, Paul KE, Chabinyc ML, Whitesides GM. Fabrication of palladium-based microelectronic devices by microcontact printing Applied Physics Letters. 80: 2222-2224. DOI: 10.1063/1.1463719  1
2002 Love JC, Gates BD, Wolfe DB, Paul KE, Whitesides GM. Fabrication and Wetting Properties of Metallic Half-Shells with Submicron Diameters Nano Letters. 2: 891-894. DOI: 10.1021/Nl025633L  1
2002 Odom TW, Love JC, Wolfe DB, Paul KE, Whitesides GM. Improved pattern transfer in soft lithography using composite stamps Langmuir. 18: 5314-5320. DOI: 10.1021/La020169L  1
2002 Yang H, Love JC, Arias F, Whitesides GM. Electroforming of copper structures at nanometer-sized gaps of self-assembled monolayers on silver Chemistry of Materials. 14: 1385-1390. DOI: 10.1021/Cm011513N  1
2002 Gracias DH, Kavthekar V, Love JC, Paul KE, Whitesides GM. Fabrication of micrometer-scale, patterned polyhedra by self-assembly Advanced Materials. 14: 235-238. DOI: 10.1002/1521-4095(20020205)14:3<235::Aid-Adma235>3.0.Co;2-B  1
2001 Paul KE, Zhu C, Love JC, Whitesides GM. Fabrication of mid-infrared frequency-selective surfaces by soft lithography. Applied Optics. 40: 4557-61. PMID 18360497 DOI: 10.1364/Ao.40.004557  1
2001 Love JC, Wolfe DB, Jacobs HO, Whitesides GM. Microscope projection photolithography for rapid prototyping of masters with micron-scale features for use in soft lithography Langmuir. 17: 6005-6012. DOI: 10.1021/La010655T  1
2001 Love JC, Paul KE, Whitesides GM. Fabrication of nanometer-scale features by controlled isotropic wet chemical etching Advanced Materials. 13: 604-608. DOI: 10.1002/1521-4095(200104)13:8<604::Aid-Adma604>3.0.Co;2-J  1
2001 Smith AP, Savage SA, Love JC, Fraser CL. Synthesis of 4-, 5-, and 6-methyl-2,2′-bipyridine by a Negishi cross-coupling strategy: 5-Methyl-2,2′-bipyridine Organic Syntheses. 78: 51-60.  1
2001 Whitesides GM, Love JC. The art of building small Scientific American. 285: 32-41.  1
2001 Love JC, Anderson JR, Whitesides GM. Fabrication of three-dimensional microfluidic systems by soft lithography Mrs Bulletin. 26: 523-528.  1
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