Thomas E. Edwards, Ph.D. - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
chemistry and structural biology of nucleic acids

115 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Demars A, Vitali A, Comein A, Carlier E, Azouz A, Goriely S, Smout J, Flamand V, Van Gysel M, Wouters J, Abendroth J, Edwards TE, Machelart A, Hoffmann E, Brodin P, et al. Aconitate decarboxylase 1 participates in the control of pulmonary Brucella infection in mice. Plos Pathogens. 17: e1009887. PMID 34525130 DOI: 10.1371/journal.ppat.1009887  1
2021 Schirmer T, de Beer TAP, Tamegger S, Harms A, Dietz N, Dranow DM, Edwards TE, Myler PJ, Phan I, Dehio C. Evolutionary Diversification of Host-Targeted Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms. 9. PMID 34442725 DOI: 10.3390/microorganisms9081645  1
2021 Ghafoori SM, Robles AM, Arada AM, Shirmast P, Dranow DM, Mayclin SJ, Lorimer DD, Myler PJ, Edwards TE, Kuhn ML, Forwood JK. Structural characterization of a Type B chloramphenicol acetyltransferase from the emerging pathogen Elizabethkingia anophelis NUHP1. Scientific Reports. 11: 9453. PMID 33947893 DOI: 10.1038/s41598-021-88672-z  1
2021 Nagaratnam N, Delker SL, Jernigan R, Edwards TE, Snider J, Thifault D, Williams D, Nannenga BL, Stofega M, Sambucetti L, Hsieh JJ, Flint AJ, Fromme P, Martin-Garcia JM. Structural insights into the function of the catalytically active human Taspase1. Structure (London, England : 1993). PMID 33784495 DOI: 10.1016/j.str.2021.03.008  0.01
2021 Tillery L, Barrett K, Goldstein J, Lassner JW, Osterhout B, Tran NL, Xu L, Young RM, Craig J, Chun I, Dranow DM, Abendroth J, Delker SL, Davies DR, Mayclin SJ, ... ... Edwards TE, et al. Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba. Plos One. 16: e0241738. PMID 33760815 DOI: 10.1371/journal.pone.0241738  1
2021 Rodarte JV, Abendroth J, Edwards TE, Lorimer DD, Staker BL, Zhang S, Myler PJ, McLaughlin KJ. Crystal structure of acetoacetyl-CoA reductase from Rickettsia felis. Acta Crystallographica. Section F, Structural Biology Communications. 77: 54-60. PMID 33620038 DOI: 10.1107/S2053230X21001497  1
2021 Shirmast P, Ghafoori SM, Irwin RM, Abendroth J, Mayclin SJ, Lorimer DD, Edwards TE, Forwood JK. Structural characterization of a GNAT family acetyltransferase from Elizabethkingia anophelis bound to acetyl-CoA reveals a new dimeric interface. Scientific Reports. 11: 1274. PMID 33446675 DOI: 10.1038/s41598-020-79649-5  1
2020 Patel S, Smith T, Morton MD, Stiers K, Seravalli J, Mayclin S, Edwards T, Tanner JJ, Becker DF. Cautionary tale of using tris(alkyl)phosphine reducing agents with NAD-dependent enzymes. Biochemistry. PMID 32841567 DOI: 10.1021/Acs.Biochem.0C00490  0.01
2020 Edwards T, Williams C, Teethaisong Y, Sealey J, Sasaki S, Hobbs G, Cuevas LE, Evans K, Adams ER. A highly multiplexed melt-curve assay for detecting the most prevalent carbapenemase, ESBL, and AmpC genes. Diagnostic Microbiology and Infectious Disease. 97: 115076. PMID 32521424 DOI: 10.1016/j.diagmicrobio.2020.115076  0.01
2020 Tillery L, Barrett K, Dranow DM, Craig J, Shek R, Chun I, Barrett LK, Phan I, Subramanian S, Abendroth J, Lorimer DD, Edwards TE, Van Voorhis WC. Towards a structome of Acinetobacter baumannii drug targets. Protein Science : a Publication of the Protein Society. PMID 31930600 DOI: 10.1002/pro.3826  1
2020 Barrett KF, Dranow DM, Phan I, Michaels SA, Shaheen S, Navaluna ED, Craig JK, Tillery LM, Choi R, Edwards TE, Conrady DG, Abendroth J, Horanyi PS, Lorimer DD, Van Voorhis WC, et al. Structures of glyceraldehyde 3-phosphate dehydrogenase in Neisseria gonorrhoeae and Chlamydia trachomatis. Protein Science : a Publication of the Protein Society. PMID 31930578 DOI: 10.1002/Pro.3824  1
2019 Ghosh S, Padalia J, Ngobeni R, Abendroth J, Farr L, Shirley DA, Edwards T, Moonah S. Targeting parasite-produced MIF as an anti-virulence strategy with antibiotic-antibody combination to reduce tissue damage. The Journal of Infectious Diseases. PMID 31677380 DOI: 10.1093/Infdis/Jiz579  1
2019 Buchko GW, Abendroth J, Robinson JI, Phan I, Myler PJ, Edwards TE. Structural diversity in the Mycobacteria DUF3349 superfamily. Protein Science : a Publication of the Protein Society. PMID 31658388 DOI: 10.1002/Pro.3758  1
2019 Lerch TF, Sharpe P, Mayclin SJ, Edwards TE, Polleck S, Rouse JC, Zou Q, Conlon HD. Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar. Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. PMID 31650490 DOI: 10.1007/s40259-019-00390-1  1
2019 Baragaña B, Forte B, Choi R, Nakazawa Hewitt S, Bueren-Calabuig JA, Pisco JP, Peet C, Dranow DM, Robinson DA, Jansen C, Norcross NR, Vinayak S, Anderson M, Brooks CF, Cooper CA, ... ... Edwards TE, et al. Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30894487 DOI: 10.1073/Pnas.1814685116  1
2019 Sullivan AH, Dranow DM, Horanyi PS, Lorimer DD, Edwards TE, Abendroth J. Crystal structures of thiamine monophosphate kinase from Acinetobacter baumannii in complex with substrates and products. Scientific Reports. 9: 4392. PMID 30867460 DOI: 10.1038/S41598-019-40558-X  1
2018 Pratt R, Handelman GJ, Edwards TE, Gupta A. Ferric pyrophosphate citrate: interactions with transferrin. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. PMID 30311019 DOI: 10.1007/S10534-018-0142-2  0.01
2018 Abendroth J, Sankaran B, Myler PJ, Lorimer DD, Edwards TE. Ab initio structure solution of a proteolytic fragment using ARCIMBOLDO. Acta Crystallographica. Section F, Structural Biology Communications. 74: 530-535. PMID 30198884 DOI: 10.1107/S2053230X18010063  1
2018 Asojo OA, Dranow DM, Serbzhinskiy D, Subramanian S, Staker B, Edwards TE, Myler PJ. Crystal structure of chorismate mutase from Burkholderia thailandensis. Acta Crystallographica. Section F, Structural Biology Communications. 74: 294-299. PMID 29717997 DOI: 10.1107/S2053230X1800506X  1
2018 Asojo OA, Subramanian S, Abendroth J, Exley I, Lorimer DD, Edwards TE, Myler PJ. Crystal structure of chorismate mutase from Burkholderia phymatum. Acta Crystallographica. Section F, Structural Biology Communications. 74: 187-192. PMID 29633965 DOI: 10.1107/S2053230X18002868  1
2018 Helgren TR, Seven ES, Chen C, Edwards TE, Staker BL, Abendroth J, Myler PJ, Horn JR, Hagen TJ. The identification of inhibitory compounds of Rickettsia prowazekii methionine aminopeptidase for antibacterial applications. Bioorganic & Medicinal Chemistry Letters. PMID 29551481 DOI: 10.1016/J.Bmcl.2018.03.002  1
2017 Abendroth J, Frando A, Phan IQ, Staker BL, Myler PJ, Edwards TE, Grundner C. Mycobacterium tuberculosis Rv3651 is a triple sensor-domain protein. Protein Science : a Publication of the Protein Society. PMID 29119630 DOI: 10.1002/Pro.3343  1
2017 Kenniston JA, Taylor BM, Conley GP, Cosic J, Kopacz KJ, Lindberg AP, Comeau SR, Atkins K, Bullen J, TenHoor C, Adelman BA, Sexton DJ, Edwards TE, Nixon AE. Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody. The Journal of Biological Chemistry. PMID 28878017 DOI: 10.1074/Jbc.M117.807396  1
2017 Lerch TF, Sharpe P, Mayclin SJ, Edwards TE, Lee E, Conlon HD, Polleck S, Rouse JC, Luo Y, Zou Q. Infliximab crystal structures reveal insights into self-association. Mabs. 0. PMID 28421849 DOI: 10.1080/19420862.2017.1320463  1
2017 Dyck B, Branstetter B, Gharbaoui T, Hudson AR, Breitenbucher JG, Gomez L, Botrous I, Marrone T, Barido R, Allerston CK, Cedervall EP, Xu R, Sridhar V, Barker R, Aertgeerts K, ... ... Edwards TE, et al. Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties. Journal of Medicinal Chemistry. PMID 28406621 DOI: 10.1021/Acs.Jmedchem.7B00302  0.01
2017 Varela-Ramirez A, Abendroth J, Mejia AA, Phan IQ, Lorimer DD, Edwards TE, Aguilera RJ. Structure of acid deoxyribonuclease. Nucleic Acids Research. PMID 28369538 DOI: 10.1093/Nar/Gkx222  1
2017 Abbara A, Chitty S, Roe JK, Ghani R, Collin SM, Ritchie A, Kon OM, Dzvova J, Davidson H, Edwards TE, Hateley C, Routledge M, Buckley J, Davidson RN, John L. Drug-induced liver injury from antituberculous treatment: a retrospective study from a large TB centre in the UK. Bmc Infectious Diseases. 17: 231. PMID 28340562 DOI: 10.1186/s12879-017-2330-z  0.01
2017 Moen SO, Edwards TE, Dranow DM, Clifton MC, Sankaran B, Van Voorhis WC, Sharma A, Manoil C, Staker BL, Myler PJ, Lorimer DD. Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms. Scientific Reports. 7: 223. PMID 28303005 DOI: 10.1038/S41598-017-00367-6  1
2017 Kirschberg TA, Metobo S, Clarke MO, Aktoudianakis V, Babusis D, Barauskas O, Birkus G, Butler T, Byun D, Chin G, Doerffler E, Edwards TE, Fenaux M, Lee R, Lew W, et al. Discovery of a 2'-fluoro-2'-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties. Bioorganic & Medicinal Chemistry Letters. PMID 28274633 DOI: 10.1016/J.Bmcl.2017.02.037  1
2017 Haft DH, Pierce PG, Mayclin SJ, Sullivan A, Gardberg AS, Abendroth J, Begley DW, Phan IQ, Staker BL, Myler PJ, Marathias VM, Lorimer DD, Edwards TE. Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors. Scientific Reports. 7: 41074. PMID 28120876 DOI: 10.1038/Srep41074  1
2016 Helgren TR, Chen C, Wangtrakuldee P, Edwards TE, Staker BL, Abendroth J, Sankaran B, Housley NA, Myler PJ, Audia JP, Horn JR, Hagen TJ. Rickettsia prowazekii methionine aminopeptidase as a promising target for the development of antibacterial agents. Bioorganic & Medicinal Chemistry. PMID 28089350 DOI: 10.1016/J.Bmc.2016.11.013  1
2016 McKary MG, Abendroth J, Edwards TE, Johnson RJ. Structural Basis for the Strict Substrate Selectivity of the Mycobacterial Hydrolase LipW. Biochemistry. PMID 27936614 DOI: 10.1021/Acs.Biochem.6B01057  1
2016 Nakazawa Hewitt S, Dranow DM, Horst BG, Abendroth JA, Forte B, Hallyburton I, Jansen C, Baragana B, Choi R, Rivas KL, Hulverson MA, Dumais M, Edwards TE, Lorimer DD, Fairlamb AH, et al. Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase. Acs Infectious Diseases. PMID 27798837 DOI: 10.1021/Acsinfecdis.6B00078  1
2016 Ojo KK, Ranade RM, Zhang Z, Dranow DM, Myers JB, Choi R, Nakazawa Hewitt S, Edwards TE, Davies DR, Lorimer D, Boyle SM, Barrett LK, Buckner FS, Fan E, Van Voorhis WC. Correction: Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis. Plos One. 11: e0163641. PMID 27658298 DOI: 10.1371/Journal.Pone.0163641  1
2016 Ojo KK, Ranade RM, Zhang Z, Dranow DM, Myers JB, Choi R, Nakazawa Hewitt S, Edwards TE, Davies DR, Lorimer D, Boyle SM, Barrett LK, Buckner FS, Fan E, Van Voorhis WC. Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis. Plos One. 11: e0160350. PMID 27500735 DOI: 10.1371/Journal.Pone.0160350  1
2015 Gillespie JJ, Phan IQ, Scheib H, Subramanian S, Edwards TE, Lehman SS, Piitulainen H, Sayeedur Rahman M, Rennoll-Bankert KE, Staker BL, Taira S, Stacy R, Myler PJ, Azad AF, Pulliainen AT. Structural Insight into How Bacteria Prevent Interference between Multiple Divergent Type IV Secretion Systems. Mbio. 6. PMID 26646013 DOI: 10.1128/Mbio.01867-15  1
2015 Oliva Chávez AS, Fairman JW, Felsheim RF, Nelson CM, Herron MJ, Higgins L, Burkhardt NY, Oliver JD, Markowski TW, Kurtti TJ, Edwards TE, Munderloh UG. An O-Methyltransferase Is Required for Infection of Tick Cells by Anaplasma phagocytophilum. Plos Pathogens. 11: e1005248. PMID 26544981 DOI: 10.1371/Journal.Ppat.1005248  1
2015 Jarvis TC, Davies DR, Hisaminato A, Resnicow DI, Gupta S, Waugh SM, Nagabukuro A, Wadatsu T, Hishigaki H, Gawande B, Zhang C, Wolk SK, Mayfield WS, Nakaishi Y, Burgin AB, ... ... Edwards TE, et al. Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor. Structure (London, England : 1993). 23: 1293-304. PMID 26027732 DOI: 10.1016/J.Str.2015.03.027  1
2015 Phan IQ, Davies DR, Moretti NS, Shanmugam D, Cestari I, Anupama A, Fairman JW, Edwards TE, Stuart K, Schenkman S, Myler PJ. Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures. Acta Crystallographica. Section F, Structural Biology Communications. 71: 615-21. PMID 25961325 DOI: 10.1107/S2053230X15004185  1
2015 Clifton MC, Bruhn JF, Atkins K, Webb TL, Baydo RO, Raymond A, Lorimer DD, Edwards TE, Myler PJ, Saphire EO. High-resolution Crystal Structure of Dimeric VP40 From Sudan ebolavirus. The Journal of Infectious Diseases. 212: S167-71. PMID 25957961 DOI: 10.1093/Infdis/Jiv090  1
2015 Buchko GW, Edwards TE, Hewitt SN, Phan IQ, Van Voorhis WC, Miller SI, Myler PJ. Backbone chemical shift assignments for the sensor domain of the Burkholderia pseudomallei histidine kinase RisS: "missing" resonances at the dimer interface. Biomolecular Nmr Assignments. PMID 25957069 DOI: 10.1007/S12104-015-9614-2  1
2015 Moen SO, Fairman JW, Barnes SR, Sullivan A, Nakazawa-Hewitt S, Van Voorhis WC, Staker BL, Lorimer DD, Myler PJ, Edwards TE. Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP. Acta Crystallographica. Section F, Structural Biology Communications. 71: 609-14. PMID 25945716 DOI: 10.1107/S2053230X15006883  1
2015 Serbzhinskiy DA, Clifton MC, Sankaran B, Staker BL, Edwards TE, Myler PJ. Structure of an ADP-ribosylation factor, ARF1, from Entamoeba histolytica bound to Mg(2+)-GDP. Acta Crystallographica. Section F, Structural Biology Communications. 71: 594-9. PMID 25945714 DOI: 10.1107/S2053230X15004677  1
2015 Lorimer DD, Choi R, Abramov A, Nakazawa Hewitt S, Gardberg AS, Van Voorhis WC, Staker BL, Myler PJ, Edwards TE. Structures of a histidine triad family protein from Entamoeba histolytica bound to sulfate, AMP and GMP. Acta Crystallographica. Section F, Structural Biology Communications. 71: 572-6. PMID 25945711 DOI: 10.1107/S2053230X1500237X  1
2015 Abendroth J, Choi R, Wall A, Clifton MC, Lukacs CM, Staker BL, Van Voorhis W, Myler P, Lorimer DD, Edwards TE. Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. Acta Crystallographica. Section F, Structural Biology Communications. 71: 566-71. PMID 25945710 DOI: 10.1107/S2053230X15001831  1
2015 Edwards TE, Gardberg AS, Phan IQ, Zhang Y, Staker BL, Myler PJ, Lorimer DD. Structure of uridine diphosphate N-acetylglucosamine pyrophosphorylase from Entamoeba histolytica. Acta Crystallographica. Section F, Structural Biology Communications. 71: 560-5. PMID 25945709 DOI: 10.1107/S2053230X1500179X  1
2015 Buchko GW, Abendroth J, Clifton MC, Robinson H, Zhang Y, Hewitt SN, Staker BL, Edwards TE, Van Voorhis WC, Myler PJ. Structure of a CutA1 divalent-cation tolerance protein from Cryptosporidium parvum, the protozoal parasite responsible for cryptosporidiosis. Acta Crystallographica. Section F, Structural Biology Communications. 71: 522-30. PMID 25945704 DOI: 10.1107/S2053230X14028210  1
2015 Edwards TE, Baugh L, Bullen J, Baydo RO, Witte P, Thompkins K, Phan IQ, Abendroth J, Clifton MC, Sankaran B, Van Voorhis WC, Myler PJ, Staker BL, Grundner C, Lorimer DD. Crystal structures of Mycobacterial MeaB and MMAA-like GTPases. Journal of Structural and Functional Genomics. 16: 91-9. PMID 25832174 DOI: 10.1007/S10969-015-9197-2  1
2015 Appleby TC, Perry JK, Murakami E, Barauskas O, Feng J, Cho A, Fox D, Wetmore DR, McGrath ME, Ray AS, Sofia MJ, Swaminathan S, Edwards TE. Viral replication. Structural basis for RNA replication by the hepatitis C virus polymerase. Science (New York, N.Y.). 347: 771-5. PMID 25678663 DOI: 10.1126/Science.1259210  1
2015 Baugh L, Phan I, Begley DW, Clifton MC, Armour B, Dranow DM, Taylor BM, Muruthi MM, Abendroth J, Fairman JW, Fox D, Dieterich SH, Staker BL, Gardberg AS, Choi R, ... ... Edwards TE, et al. Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinburgh, Scotland). 95: 142-8. PMID 25613812 DOI: 10.1016/J.Tube.2014.12.003  1
2014 Moreno MA, Alonso A, Alcolea PJ, Abramov A, de Lacoba MG, Abendroth J, Zhang S, Edwards T, Lorimer D, Myler PJ, Larraga V. Tyrosine aminotransferase from Leishmania infantum: A new drug target candidate. International Journal For Parasitology. Drugs and Drug Resistance. 4: 347-54. PMID 25516846 DOI: 10.1016/J.Ijpddr.2014.06.001  1
2014 Lam AM, Edwards TE, Mosley RT, Murakami E, Bansal S, Lugo C, Bao H, Otto MJ, Sofia MJ, Furman PA. Molecular and structural basis for the roles of hepatitis C virus polymerase NS5B amino acids 15, 223, and 321 in viral replication and drug resistance. Antimicrobial Agents and Chemotherapy. 58: 6861-9. PMID 25182647 DOI: 10.1128/Aac.03847-14  1
2014 Moen SO, Abendroth J, Fairman JW, Baydo RO, Bullen J, Kirkwood JL, Barnes SR, Raymond AC, Begley DW, Henkel G, McCormack K, Tam VC, Phan I, Staker BL, Stacy R, ... ... Edwards TE, et al. Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1. Scientific Reports. 4: 5944. PMID 25089892 DOI: 10.1038/Srep05944  1
2014 Kenniston JA, Faucette RR, Martik D, Comeau SR, Lindberg AP, Kopacz KJ, Conley GP, Chen J, Viswanathan M, Kastrapeli N, Cosic J, Mason S, DiLeo M, Abendroth J, Kuzmic P, ... ... Edwards TE, et al. Inhibition of plasma kallikrein by a highly specific active site blocking antibody. The Journal of Biological Chemistry. 289: 23596-608. PMID 24970892 DOI: 10.1074/Jbc.M114.569061  1
2014 Moreno MA, Abramov A, Abendroth J, Alonso A, Zhang S, Alcolea PJ, Edwards T, Lorimer D, Myler PJ, Larraga V. Structure of tyrosine aminotransferase from Leishmania infantum. Acta Crystallographica. Section F, Structural Biology Communications. 70: 583-7. PMID 24817714 DOI: 10.1107/S2053230X14007845  1
2014 Clifton MC, Kirchdoerfer RN, Atkins K, Abendroth J, Raymond A, Grice R, Barnes S, Moen S, Lorimer D, Edwards TE, Myler PJ, Saphire EO. Structure of the Reston ebolavirus VP30 C-terminal domain. Acta Crystallographica. Section F, Structural Biology Communications. 70: 457-60. PMID 24699737 DOI: 10.1107/S2053230X14003811  1
2014 Linford AS, Jiang NM, Edwards TE, Sherman NE, Van Voorhis WC, Stewart LJ, Myler PJ, Staker BL, Petri WA. Crystal structure and putative substrate identification for the Entamoeba histolytica low molecular weight tyrosine phosphatase. Molecular and Biochemical Parasitology. 193: 33-44. PMID 24548880 DOI: 10.1016/J.Molbiopara.2014.01.003  1
2014 Gelinas AD, Davies DR, Edwards TE, Rohloff JC, Carter JD, Zhang C, Gupta S, Ishikawa Y, Hirota M, Nakaishi Y, Jarvis TC, Janjic N. Crystal structure of interleukin-6 in complex with a modified nucleic acid ligand. The Journal of Biological Chemistry. 289: 8720-34. PMID 24415767 DOI: 10.1074/Jbc.M113.532697  1
2014 Begley DW, Fox D, Jenner D, Juli C, Pierce PG, Abendroth J, Muruthi M, Safford K, Anderson V, Atkins K, Barnes SR, Moen SO, Raymond AC, Stacy R, Myler PJ, ... ... Edwards TE, et al. A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrobial Agents and Chemotherapy. 58: 1458-67. PMID 24366729 DOI: 10.1128/Aac.01875-13  1
2014 Abendroth J, Ollodart A, Andrews ES, Myler PJ, Staker BL, Edwards TE, Arcus VL, Grundner C. Mycobacterium tuberculosis Rv2179c protein establishes a new exoribonuclease family with broad phylogenetic distribution. The Journal of Biological Chemistry. 289: 2139-47. PMID 24311791 DOI: 10.1074/Jbc.M113.525683  1
2014 Edwards TE, Sigurdsson ST. Modified RNAs as Tools in RNA Biochemistry Handbook of Rna Biochemistry: Second, Completely Revised and Enlarged Edition. 1: 151-172. DOI: 10.1002/9783527647064.ch8  1
2013 Zhang Z, Jakkaraju S, Blain J, Gogol K, Zhao L, Hartley RC, Karlsson CA, Staker BL, Edwards TE, Stewart LJ, Myler PJ, Clare M, Begley DW, Horn JR, Hagen TJ. Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei. Bioorganic & Medicinal Chemistry Letters. 23: 6860-3. PMID 24157367 DOI: 10.1016/J.Bmcl.2013.09.101  1
2013 Armour BL, Barnes SR, Moen SO, Smith E, Raymond AC, Fairman JW, Stewart LJ, Staker BL, Begley DW, Edwards TE, Lorimer DD. Multi-target parallel processing approach for gene-to-structure determination of the influenza polymerase PB2 subunit. Journal of Visualized Experiments : Jove. PMID 23851357 DOI: 10.3791/4225  1
2013 Bocedi A, Fabrini R, Farrotti A, Stella L, Ketterman AJ, Pedersen JZ, Allocati N, Lau PC, Grosse S, Eltis LD, Ruzzini A, Edwards TE, Morici L, Del Grosso E, Guidoni L, et al. The impact of nitric oxide toxicity on the evolution of the glutathione transferase superfamily: a proposal for an evolutionary driving force. The Journal of Biological Chemistry. 288: 24936-47. PMID 23828197 DOI: 10.1074/Jbc.M113.476135  1
2013 Buchko GW, Abendroth J, Robinson H, Zhang Y, Hewitt SN, Edwards TE, Van Voorhis WC, Myler PJ. Crystal structure of a macrophage migration inhibitory factor from Giardia lamblia. Journal of Structural and Functional Genomics. 14: 47-57. PMID 23709284 DOI: 10.1007/S10969-013-9155-9  1
2013 Zhang Y, Gardberg AS, Edwards TE, Sankaran B, Robinson H, Varnum SM, Buchko GW. Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D. Biochimie. 95: 1379-85. PMID 23523511 DOI: 10.1016/J.Biochi.2013.03.006  1
2013 Baugh L, Gallagher LA, Patrapuvich R, Clifton MC, Gardberg AS, Edwards TE, Armour B, Begley DW, Dieterich SH, Dranow DM, Abendroth J, Fairman JW, Fox D, Staker BL, Phan I, et al. Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One. 8: e53851. PMID 23382856 DOI: 10.1371/Journal.Pone.0053851  1
2012 Davies DR, Gelinas AD, Zhang C, Rohloff JC, Carter JD, O'Connell D, Waugh SM, Wolk SK, Mayfield WS, Burgin AB, Edwards TE, Stewart LJ, Gold L, Janjic N, Jarvis TC. Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets. Proceedings of the National Academy of Sciences of the United States of America. 109: 19971-6. PMID 23139410 DOI: 10.1073/Pnas.1213933109  1
2012 Edwards TE, Liao R, Phan I, Myler PJ, Grundner C. Mycobacterium thermoresistibile as a source of thermostable orthologs of Mycobacterium tuberculosis proteins. Protein Science : a Publication of the Protein Society. 21: 1093-6. PMID 22544630 DOI: 10.1002/Pro.2084  1
2012 Mosley RT, Edwards TE, Murakami E, Lam AM, Grice RL, Du J, Sofia MJ, Furman PA, Otto MJ. Structure of hepatitis C virus polymerase in complex with primer-template RNA. Journal of Virology. 86: 6503-11. PMID 22496223 DOI: 10.1128/Jvi.00386-12  1
2011 Edwards TE, Abramov AB, Smith ER, Baydo RO, Leonard JT, Leibly DJ, Thompkins KB, Clifton MC, Gardberg AS, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ. Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis. Bmc Structural Biology. 11: 39. PMID 21995815 DOI: 10.1186/1472-6807-11-39  1
2011 Clifton MC, Abendroth J, Edwards TE, Leibly DJ, Gillespie AK, Ferrell M, Dieterich SH, Exley I, Staker BL, Myler PJ, Van Voorhis WC, Stewart LJ. Structure of the cystathionine γ-synthase MetB from Mycobacterium ulcerans. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1154-8. PMID 21904066 DOI: 10.1107/S1744309111029575  1
2011 Phan I, Subramanian S, Olsen C, Edwards TE, Guo W, Zhang Y, Van Voorhis WC, Stewart LJ, Myler PJ. Structure of fumarate hydratase from Rickettsia prowazekii, the agent of typhus and suspected relative of the mitochondria. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1123-8. PMID 21904061 DOI: 10.1107/S174430911102690X  1
2011 Ferrell M, Abendroth J, Zhang Y, Sankaran B, Edwards TE, Staker BL, Van Voorhis WC, Stewart LJ, Myler PJ. Structure of aldose reductase from Giardia lamblia. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1113-7. PMID 21904059 DOI: 10.1107/S1744309111030879  1
2011 Abendroth J, Sankaran B, Edwards TE, Gardberg AS, Dieterich S, Bhandari J, Napuli AJ, Van Voorhis WC, Staker BL, Myler PJ, Stewart LJ. BrabA.11339.a: anomalous diffraction and ligand binding guide towards the elucidation of the function of a 'putative β-lactamase-like protein' from Brucella melitensis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1106-12. PMID 21904058 DOI: 10.1107/S1744309111010220  1
2011 Zhang Y, Edwards TE, Begley DW, Abramov A, Thompkins KB, Ferrell M, Guo WJ, Phan I, Olsen C, Napuli A, Sankaran B, Stacy R, Van Voorhis WC, Stewart LJ, Myler PJ. Structure of nitrilotriacetate monooxygenase component B from Mycobacterium thermoresistibile. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1100-5. PMID 21904057 DOI: 10.1107/S1744309111012541  1
2011 Buchko GW, Edwards TE, Abendroth J, Arakaki TL, Law L, Napuli AJ, Hewitt SN, Van Voorhis WC, Stewart LJ, Staker BL, Myler PJ. Structure of a Nudix hydrolase (MutT) in the Mg(2+)-bound state from Bartonella henselae, the bacterium responsible for cat scratch fever. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1078-83. PMID 21904053 DOI: 10.1107/S1744309111011559  1
2011 Begley DW, Edwards TE, Raymond AC, Smith ER, Hartley RC, Abendroth J, Sankaran B, Lorimer DD, Myler PJ, Staker BL, Stewart LJ. Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1070-7. PMID 21904052 DOI: 10.1107/S1744309111029009  1
2011 Davies DR, Staker BL, Abendroth JA, Edwards TE, Hartley R, Leonard J, Kim H, Rychel AL, Hewitt SN, Myler PJ, Stewart LJ. An ensemble of structures of Burkholderia pseudomallei 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1044-50. PMID 21904048 DOI: 10.1107/S1744309111030405  1
2011 Edwards TE, Bryan CM, Leibly DJ, Dieterich SH, Abendroth J, Sankaran B, Sivam D, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ. Structures of a putative ζ-class glutathione S-transferase from the pathogenic fungus Coccidioides immitis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1038-43. PMID 21904047 DOI: 10.1107/S1744309111009493  1
2011 Edwards TE, Leibly DJ, Bhandari J, Statnekov JB, Phan I, Dieterich SH, Abendroth J, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ. Structures of phosphopantetheine adenylyltransferase from Burkholderia pseudomallei. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1032-7. PMID 21904046 DOI: 10.1107/S1744309111004349  1
2011 Smith ER, Begley DW, Anderson V, Raymond AC, Haffner TE, Robinson JI, Edwards TE, Duncan N, Gerdts CJ, Mixon MB, Nollert P, Staker BL, Stewart LJ. The Protein Maker: an automated system for high-throughput parallel purification. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1015-21. PMID 21904043 DOI: 10.1107/S1744309111028776  1
2011 Bryan CM, Bhandari J, Napuli AJ, Leibly DJ, Choi R, Kelley A, Van Voorhis WC, Edwards TE, Stewart LJ. High-throughput protein production and purification at the Seattle Structural Genomics Center for Infectious Disease. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1010-4. PMID 21904042 DOI: 10.1107/S1744309111018367  1
2011 Yates SP, Edwards TE, Bryan CM, Stein AJ, Van Voorhis WC, Myler PJ, Stewart LJ, Zheng J, Jia Z. Structural basis of the substrate specificity of bifunctional isocitrate dehydrogenase kinase/phosphatase. Biochemistry. 50: 8103-6. PMID 21870819 DOI: 10.1021/Bi200809P  1
2011 Begley DW, Davies DR, Hartley RC, Edwards TE, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ. Fragment screening of infectious disease targets in a structural genomics environment. Methods in Enzymology. 493: 533-56. PMID 21371605 DOI: 10.1016/B978-0-12-381274-2.00021-2  1
2011 Abendroth J, Gardberg AS, Robinson JI, Christensen JS, Staker BL, Myler PJ, Stewart LJ, Edwards TE. SAD phasing using iodide ions in a high-throughput structural genomics environment. Journal of Structural and Functional Genomics. 12: 83-95. PMID 21359836 DOI: 10.1007/S10969-011-9101-7  1
2011 Begley DW, Hartley RC, Davies DR, Edwards TE, Leonard JT, Abendroth J, Burris CA, Bhandari J, Myler PJ, Staker BL, Stewart LJ. Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. Journal of Structural and Functional Genomics. 12: 63-76. PMID 21359640 DOI: 10.1007/S10969-011-9102-6  1
2011 Edwards TE, Cekan P, Reginsson GW, Shelke SA, Ferré-D'Amaré AR, Schiemann O, Sigurdsson ST. Crystal structure of a DNA containing the planar, phenoxazine-derived bi-functional spectroscopic probe C. Nucleic Acids Research. 39: 4419-26. PMID 21252294 DOI: 10.1093/Nar/Gkr015  1
2010 Gerdts CJ, Stahl GL, Napuli A, Staker B, Abendroth J, Edwards TE, Myler P, Van Voorhis W, Nollert P, Stewart LJ. Nanovolume optimization of protein crystal growth using the microcapillary protein crystallization system. Journal of Applied Crystallography. 43: 1078-1083. PMID 22477778 DOI: 10.1107/S0021889810027378  1
2010 Edwards TE, Phan I, Abendroth J, Dieterich SH, Masoudi A, Guo W, Hewitt SN, Kelley A, Leibly D, Brittnacher MJ, Staker BL, Miller SI, Van Voorhis WC, Myler PJ, Stewart LJ. Structure of a Burkholderia pseudomallei trimeric autotransporter adhesin head. Plos One. 5. PMID 20862217 DOI: 10.1371/Journal.Pone.0012803  1
2010 Abendroth J, McCormick MS, Edwards TE, Staker B, Loewen R, Gifford M, Rifkin J, Mayer C, Guo W, Zhang Y, Myler P, Kelley A, Analau E, Hewitt SN, Napuli AJ, et al. X-ray structure determination of the glycine cleavage system protein H of Mycobacterium tuberculosis using an inverse Compton synchrotron X-ray source. Journal of Structural and Functional Genomics. 11: 91-100. PMID 20364333 DOI: 10.1007/S10969-010-9087-6  1
2010 Kulshina N, Edwards TE, Ferré-D'Amaré AR. Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch. Rna (New York, N.Y.). 16: 186-96. PMID 19948769 DOI: 10.1261/Rna.1847310  1
2009 Klein DJ, Edwards TE, Ferré-D'Amaré AR. Cocrystal structure of a class I preQ1 riboswitch reveals a pseudoknot recognizing an essential hypermodified nucleobase. Nature Structural & Molecular Biology. 16: 343-4. PMID 19234468 DOI: 10.1038/Nsmb.1563  1
2008 Xiao H, Edwards TE, Ferré-D'Amaré AR. Structural basis for specific, high-affinity tetracycline binding by an in vitro evolved aptamer and artificial riboswitch. Chemistry & Biology. 15: 1125-37. PMID 18940672 DOI: 10.1016/J.Chembiol.2008.09.004  1
2008 Edwards TE, Sigurdsson STH. Modified RNAs as Tools in RNA Biochemistry Handbook of Rna Biochemistry. 112-129. DOI: 10.1002/9783527619504.ch8  1
2007 Edwards TE, Sigurdsson ST. Site-specific incorporation of nitroxide spin-labels into 2'-positions of nucleic acids. Nature Protocols. 2: 1954-62. PMID 17703207 DOI: 10.1038/Nprot.2007.273  1
2007 Edwards TE, Klein DJ, Ferré-D'Amaré AR. Riboswitches: small-molecule recognition by gene regulatory RNAs. Current Opinion in Structural Biology. 17: 273-9. PMID 17574837 DOI: 10.1016/J.Sbi.2007.05.004  1
2006 Edwards TE, Ferré-D'Amaré AR. Crystal structures of the thi-box riboswitch bound to thiamine pyrophosphate analogs reveal adaptive RNA-small molecule recognition. Structure (London, England : 1993). 14: 1459-68. PMID 16962976 DOI: 10.1016/J.Str.2006.07.008  1
2005 Edwards TE, Sigurdsson ST. EPR spectroscopic analysis of U7 hammerhead ribozyme dynamics during metal ion induced folding. Biochemistry. 44: 12870-8. PMID 16171402 DOI: 10.1021/Bi050549G  1
2005 Olsen GL, Edwards TE, Deka P, Varani G, Sigurdsson ST, Drobny GP. Monitoring tat peptide binding to TAR RNA by solid-state 31P-19F REDOR NMR. Nucleic Acids Research. 33: 3447-54. PMID 15961729 DOI: 10.1093/Nar/Gki626  1
2005 Edwards TE, Robinson BH, Sigurdsson ST. Identification of amino acids that promote specific and rigid TAR RNA-tat protein complex formation. Chemistry & Biology. 12: 329-37. PMID 15797217 DOI: 10.1016/J.Chembiol.2005.01.012  1
2004 Bulger EM, Edwards T, Klotz P, Jurkovich GJ. Epidural analgesia improves outcome after multiple rib fractures. Surgery. 136: 426-430. PMID 15300210 DOI: 10.1016/J.Surg.2004.05.019  0.01
2004 Leulliot N, Quevillon-Cheruel S, Graille M, van Tilbeurgh H, Leeper TC, Godin KS, Edwards TE, Sigurdsson ST, Rozenkrants N, Nagel RJ, Ares M, Varani G. A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III. The Embo Journal. 23: 2468-77. PMID 15192703 DOI: 10.1038/Sj.Emboj.7600260  1
2003 Edwards TE, Sigurdsson ST. EPR spectroscopic analysis of TAR RNA-metal ion interactions. Biochemical and Biophysical Research Communications. 303: 721-5. PMID 12659878 DOI: 10.1016/S0006-291X(03)00411-X  1
2003 Schiemann O, Weber A, Edwards TE, Prisner TF, Sigurdsson ST. Nanometer distance measurements on RNA using PELDOR Journal of the American Chemical Society. 125: 3434-3435. PMID 12643697 DOI: 10.1021/Ja0274610  1
2002 Edwards TE, Sigurdsson ST. Electron paramagnetic resonance dynamic signatures of TAR RNA-small molecule complexes provide insight into RNA structure and recognition Biochemistry. 41: 14843-14847. PMID 12475232 DOI: 10.1021/Bi026299A  1
2002 Edwards TE, Okonogi TM, Sigurdsson ST. Investigation of RNA-protein and RNA-metal ion interactions by electron paramagnetic resonance spectroscopy. The HIV TAR-Tat motif. Chemistry & Biology. 9: 699-706. PMID 12079781 DOI: 10.1016/S1074-5521(02)00150-3  1
2001 Edwards TE, Okonogi TM, Robinson BH, Sigurdsson ST. Site-specific incorporation of nitroxide spin-labels into internal sites of the TAR RNA; structure-dependent dynamics of RNA by EPR spectroscopy. Journal of the American Chemical Society. 123: 1527-8. PMID 11456739 DOI: 10.1021/Ja005649I  1
1988 Edwards TE. The lowering of the 300-mm diameter intermediate pressure pipeline at Caverswall. Pipeline Ind. Guild. J.. 102: 15+33.  1
1964 Thomas PR, Tyler GJ, Edwards TE, Radcliffe AT, Cubbon RCP. The anionic polymerization of some alkyl vinyl ketones Polymer. 5: 525-531.  0.01
1961 Peat S, Whelan WJ, Edwards TE. 6. Polysaccharides of baker's yeast. Part IV. Mannan Journal of the Chemical Society (Resumed). 29-34.  1
1958 Peat S, Whelan WJ, Edwards TE. 785. Polysaccharides of baker's yeast. Part II. Yeast glucan Journal of the Chemical Society (Resumed). 3862-3868. DOI: 10.1039/Jr9580003862  1
1958 Peat S, Whelan WJ, Edwards TE, Owen O. 114. Quantitative aspects of the acid reversion of glucose Journal of the Chemical Society (Resumed). 586-592. DOI: 10.1039/Jr9580000586  1
1957 Deno NC, Edwards T, Perizzolo C. Carbonium Ions. V. The Nature of the t-Butyl Cation as Indicated by a Study of the Formation of N-t-Butylacrylamide1 Journal of the American Chemical Society. 79: 2108-2112. DOI: 10.1021/Ja01566A022  0.01
1955 Peat S, Whelan WJ, Edwards TE. Polysaccharides of Baker's yeast. Part I. Glycogen Journal of the Chemical Society (Resumed). 355-359. DOI: 10.1039/Jr9550000355  1
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