Matthew D. Hirschey, Ph.D. - Publications

Affiliations: 
University of California, Santa Barbara, Santa Barbara, CA, United States 
Area:
bioinorganic chemistry and metallobiochemistry

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Madsen AS, Andersen C, Daoud M, Anderson KA, Laursen JS, Chakladar S, Huynh FK, Colaço AR, Backos DS, Fristrup P, Hirschey MD, Olsen CA. Investigating the Sensitivity of NAD+-Dependent Sirtuin Deacylation Activities to NADH. The Journal of Biological Chemistry. PMID 26861872 DOI: 10.1074/jbc.M115.668699  0.32
2015 Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin AR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, ... ... Hirschey MD, et al. Designing a broad-spectrum integrative approach for cancer prevention and treatment. Seminars in Cancer Biology. 35: S276-304. PMID 26590477 DOI: 10.1016/j.semcancer.2015.09.007  0.32
2015 Hirschey MD, DeBerardinis RJ, Diehl AM, Drew JE, Frezza C, Green MF, Jones LW, Ko YH, Le A, Lea MA, Locasale JW, Longo VD, Lyssiotis CA, McDonnell E, Mehrmohamadi M, et al. Dysregulated metabolism contributes to oncogenesis. Seminars in Cancer Biology. PMID 26454069 DOI: 10.1016/j.semcancer.2015.10.002  0.32
2015 Otsubo C, Bharathi S, Uppala R, Ilkayeva OR, Wang D, McHugh K, Zou Y, Wang J, Alcorn JF, Zuo YY, Hirschey MD, Goetzman ES. Long-chain Acylcarnitines Reduce Lung Function by Inhibiting Pulmonary Surfactant. The Journal of Biological Chemistry. PMID 26240137 DOI: 10.1074/jbc.M115.655837  0.32
2015 Liu X, Sadhukhan S, Sun S, Wagner GR, Hirschey MD, Qi L, Lin H, Locasale JW. High-Resolution Metabolomics with Acyl-CoA Profiling Reveals Widespread Remodeling in Response to Diet. Molecular & Cellular Proteomics : McP. 14: 1489-500. PMID 25795660 DOI: 10.1074/mcp.M114.044859  0.32
2015 Burkewitz K, Morantte I, Weir HJ, Yeo R, Zhang Y, Huynh FK, Ilkayeva OR, Hirschey MD, Grant AR, Mair WB. Neuronal CRTC-1 governs systemic mitochondrial metabolism and lifespan via a catecholamine signal. Cell. 160: 842-55. PMID 25723162 DOI: 10.1016/j.cell.2015.02.004  0.32
2015 Glass OK, Inman BA, Broadwater G, Courneya KS, Mackey JR, Goruk S, Nelson ER, Jasper J, Field CJ, Bain JR, Muehlbauer M, Stevens RD, Hirschey MD, Jones LW. Effect of aerobic training on the host systemic milieu in patients with solid tumours: an exploratory correlative study. British Journal of Cancer. 112: 825-31. PMID 25584487 DOI: 10.1038/bjc.2014.662  0.32
2015 McDonnell E, Peterson BS, Bomze HM, Hirschey MD. SIRT3 regulates progression and development of diseases of aging Trends in Endocrinology and Metabolism. DOI: 10.1016/j.tem.2015.06.001  0.32
2014 Anderson KA, Green MF, Huynh FK, Wagner GR, Hirschey MD. SnapShot: Mammalian Sirtuins. Cell. 159: 956-956.e1. PMID 25417168 DOI: 10.1016/j.cell.2014.10.045  0.32
2014 Schechter MA, Hsieh MK, Njoroge LW, Thompson JW, Soderblom EJ, Feger BJ, Troupes CD, Hershberger KA, Ilkayeva OR, Nagel WL, Landinez GP, Shah KM, Burns VA, Santacruz L, Hirschey MD, et al. Phosphoproteomic profiling of human myocardial tissues distinguishes ischemic from non-ischemic end stage heart failure. Plos One. 9: e104157. PMID 25117565 DOI: 10.1371/journal.pone.0104157  0.32
2014 Moffat C, Bhatia L, Nguyen T, Lynch P, Wang M, Wang D, Ilkayeva OR, Han X, Hirschey MD, Claypool SM, Seifert EL. Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver. Journal of Lipid Research. 55: 2458-70. PMID 25114170 DOI: 10.1194/jlr.M046961  0.32
2014 Huynh FK, Green MF, Koves TR, Hirschey MD. Measurement of fatty acid oxidation rates in animal tissues and cell lines. Methods in Enzymology. 542: 391-405. PMID 24862277 DOI: 10.1016/B978-0-12-416618-9.00020-0  0.32
2014 Tan M, Peng C, Anderson KA, Chhoy P, Xie Z, Dai L, Park J, Chen Y, Huang H, Zhang Y, Ro J, Wagner GR, Green MF, Madsen AS, Schmiesing J, ... ... Hirschey MD, et al. Lysine glutarylation is a protein posttranslational modification regulated by SIRT5. Cell Metabolism. 19: 605-17. PMID 24703693 DOI: 10.1016/j.cmet.2014.03.014  0.32
2013 Bharathi SS, Zhang Y, Mohsen AW, Uppala R, Balasubramani M, Schreiber E, Uechi G, Beck ME, Rardin MJ, Vockley J, Verdin E, Gibson BW, Hirschey MD, Goetzman ES. Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site. The Journal of Biological Chemistry. 288: 33837-47. PMID 24121500 DOI: 10.1074/jbc.M113.510354  0.32
2013 Fritz KS, Green MF, Petersen DR, Hirschey MD. Ethanol metabolism modifies hepatic protein acylation in mice. Plos One. 8: e75868. PMID 24073283 DOI: 10.1371/journal.pone.0075868  0.32
2013 Wang D, Green MF, McDonnell E, Hirschey MD. Oxygen flux analysis to understand the biological function of sirtuins. Methods in Molecular Biology (Clifton, N.J.). 1077: 241-58. PMID 24014411 DOI: 10.1007/978-1-62703-637-5_16  0.32
2013 Hershberger KA, Motley J, Hirschey MD, Anderson KA. Generating mammalian sirtuin tools for protein-interaction analysis. Methods in Molecular Biology (Clifton, N.J.). 1077: 69-78. PMID 24014400 DOI: 10.1007/978-1-62703-637-5_5  0.32
2013 Merksamer PI, Liu Y, He W, Hirschey MD, Chen D, Verdin E. The sirtuins, oxidative stress and aging: an emerging link. Aging. 5: 144-50. PMID 23474711  0.32
2013 Shimazu T, Hirschey MD, Newman J, He W, Shirakawa K, Le Moan N, Grueter CA, Lim H, Saunders LR, Stevens RD, Newgard CB, Farese RV, de Cabo R, Ulrich S, Akassoglou K, et al. Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Science (New York, N.Y.). 339: 211-4. PMID 23223453 DOI: 10.1126/science.1227166  0.32
2013 Gut P, Baeza-Raja B, Andersson O, Hasenkamp L, Hsiao J, Hesselson D, Akassoglou K, Verdin E, Hirschey MD, Stainier DY. Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism. Nature Chemical Biology. 9: 97-104. PMID 23201900 DOI: 10.1038/nchembio.1136  0.32
2013 Anderson KA, Wang D, Hirschey MD. HINT2 and fatty liver disease: mitochondrial protein hyperacetylation gives a hint? Hepatology (Baltimore, Md.). 57: 1681-3. PMID 22991239 DOI: 10.1002/hep.26085  0.32
2013 Green MF, Hirschey MD. SIRT3 weighs heavily in the metabolic balance: a new role for SIRT3 in metabolic syndrome. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 68: 105-7. PMID 22562958 DOI: 10.1093/gerona/gls132  0.32
2012 Anderson KA, Hirschey MD. Mitochondrial protein acetylation regulates metabolism. Essays in Biochemistry. 52: 23-35. PMID 22708561 DOI: 10.1042/bse0520023  0.32
2012 Fritz KS, Galligan JJ, Hirschey MD, Verdin E, Petersen DR. Mitochondrial acetylome analysis in a mouse model of alcohol-induced liver injury utilizing SIRT3 knockout mice. Journal of Proteome Research. 11: 1633-43. PMID 22309199 DOI: 10.1021/pr2008384  0.32
2012 Streeper RS, Grueter CA, Salomonis N, Cases S, Levin MC, Koliwad SK, Zhou P, Hirschey MD, Verdin E, Farese RV. Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice. Aging. 4: 13-27. PMID 22291164  0.32
2011 Hirschey MD, Shimazu T, Huang JY, Schwer B, Verdin E. SIRT3 regulates mitochondrial protein acetylation and intermediary metabolism. Cold Spring Harbor Symposia On Quantitative Biology. 76: 267-77. PMID 22114326 DOI: 10.1101/sqb.2011.76.010850  0.32
2011 Jing E, Emanuelli B, Hirschey MD, Boucher J, Lee KY, Lombard D, Verdin EM, Kahn CR. Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. Proceedings of the National Academy of Sciences of the United States of America. 108: 14608-13. PMID 21873205 DOI: 10.1073/pnas.1111308108  0.32
2011 Hirschey MD, Shimazu T, Jing E, Grueter CA, Collins AM, Aouizerat B, Stančáková A, Goetzman E, Lam MM, Schwer B, Stevens RD, Muehlbauer MJ, Kakar S, Bass NM, Kuusisto J, et al. SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. Molecular Cell. 44: 177-90. PMID 21856199 DOI: 10.1016/j.molcel.2011.07.019  0.32
2011 Hirschey MD, Shimazu T, Capra JA, Pollard KS, Verdin E. SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2 Aging. 3: 635-642. PMID 21701047  0.32
2010 Qiu X, Brown K, Hirschey MD, Verdin E, Chen D. Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metabolism. 12: 662-7. PMID 21109198 DOI: 10.1016/j.cmet.2010.11.015  0.32
2010 Shimazu T, Hirschey MD, Hua L, Dittenhafer-Reed KE, Schwer B, Lombard DB, Li Y, Bunkenborg J, Alt FW, Denu JM, Jacobson MP, Verdin E. SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. Cell Metabolism. 12: 654-61. PMID 21109197 DOI: 10.1016/j.cmet.2010.11.003  0.32
2010 Verdin E, Hirschey MD, Finley LW, Haigis MC. Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling. Trends in Biochemical Sciences. 35: 669-75. PMID 20863707 DOI: 10.1016/j.tibs.2010.07.003  0.32
2010 Shimazu T, Hirschey MD, Huang JY, Ho LT, Verdin E. Acetate metabolism and aging: An emerging connection. Mechanisms of Ageing and Development. 131: 511-6. PMID 20478325 DOI: 10.1016/j.mad.2010.05.001  0.32
2010 Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, et al. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature. 464: 121-5. PMID 20203611 DOI: 10.1038/nature08778  0.32
2010 Huang JY, Hirschey MD, Shimazu T, Ho L, Verdin E. Mitochondrial sirtuins. Biochimica Et Biophysica Acta. 1804: 1645-51. PMID 20060508 DOI: 10.1016/j.bbapap.2009.12.021  0.32
2009 Hirschey MD, Shimazu T, Huang JY, Verdin E. Acetylation of mitochondrial proteins. Methods in Enzymology. 457: 137-47. PMID 19426866 DOI: 10.1016/S0076-6879(09)05008-3  0.32
2007 Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, et al. Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation. Molecular and Cellular Biology. 27: 8807-14. PMID 17923681 DOI: 10.1128/MCB.01636-07  0.32
2006 Hirschey MD, Han YJ, Stucky GD, Butler A. Imaging Escherichia coli using functionalized core/shell CdSe/CdS quantum dots. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 11: 663-9. PMID 16724226 DOI: 10.1007/s00775-006-0116-7  0.32
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