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Year Citation  Score
2019 Lu H, Mu W, Balagurunathan Y, Qi J, Abdalah MA, Garcia AL, Ye Z, Gillies RJ, Schabath MB. Multi-window CT based Radiomic signatures in differentiating indolent versus aggressive lung cancers in the National Lung Screening Trial: a retrospective study. Cancer Imaging : the Official Publication of the International Cancer Imaging Society. 19: 45. PMID 31253194 DOI: 10.1186/s40644-019-0232-6  1
2019 Balagurunathan Y, Schabath MB, Wang H, Liu Y, Gillies RJ. Quantitative Imaging features Improve Discrimination of Malignancy in Pulmonary nodules. Scientific Reports. 9: 8528. PMID 31189944 DOI: 10.1038/s41598-019-44562-z  1
2019 Jardim-Perassi BV, Huang S, Dominguez-Viqueira W, Poleszczuk J, Budzevich MM, Abdalah MA, Pillai SR, Ruiz E, Bui MM, Zuccari DAPC, Gillies RJ, Martinez GV. Multiparametric MRI and co-registered histology identify tumor habitats in breast cancer mouse models. Cancer Research. PMID 31186232 DOI: 10.1158/0008-5472.CAN-19-0213  1
2019 Parra NA, Lu H, Li Q, Stoyanova R, Pollack A, Punnen S, Choi J, Abdalah M, Lopez C, Gage K, Park JY, Kosj Y, Pow-Sang JM, Gillies RJ, Balagurunathan Y. Erratum: Predicting clinically significant prostate cancer using DCE-MRI habitat descriptors. Oncotarget. 10: 2113. PMID 31007853 DOI: 10.18632/oncotarget.26802  1
2019 Pillai SR, Damaghi M, Marunaka Y, Spugnini EP, Fais S, Gillies RJ. Causes, consequences, and therapy of tumors acidosis. Cancer Metastasis Reviews. PMID 30911978 DOI: 10.1007/s10555-019-09792-7  1
2019 Parra NA, Lu H, Choi J, Gage K, Pow-Sang J, Gillies RJ, Balagurunathan Y. Habitats in DCE-MRI to Predict Clinically Significant Prostate Cancers. Tomography (Ann Arbor, Mich.). 5: 68-76. PMID 30854444 DOI: 10.18383/j.tom.2018.00037  1
2019 Bi WL, Hosny A, Schabath MB, Giger ML, Birkbak NJ, Mehrtash A, Allison T, Arnaout O, Abbosh C, Dunn IF, Mak RH, Tamimi RM, Tempany CM, Swanton C, Hoffmann U, ... ... Gillies RJ, et al. Artificial intelligence in cancer imaging: Clinical challenges and applications. Ca: a Cancer Journal For Clinicians. PMID 30720861 DOI: 10.3322/caac.21552  1
2019 Choi JW, Budzevich M, Wang S, Gage K, Estrella V, Gillies RJ. In vivo positron emission tomographic blood pool imaging in an immunodeficient mouse model using 18F-fluorodeoxyglucose labeled human erythrocytes. Plos One. 14: e0211012. PMID 30682160 DOI: 10.1371/journal.pone.0211012  1
2018 Parra AN, Lu H, Li Q, Stoyanova R, Pollack A, Punnen S, Choi J, Abdalah M, Lopez C, Gage K, Park JY, Kosj Y, Pow-Sang JM, Gillies RJ, Balagurunathan Y. Predicting clinically significant prostate cancer using DCE-MRI habitat descriptors. Oncotarget. 9: 37125-37136. PMID 30647849 DOI: 10.18632/oncotarget.26437  1
2018 Cherezov D, Hawkins SH, Goldgof DB, Hall LO, Liu Y, Li Q, Balagurunathan Y, Gillies RJ, Schabath MB. Delta radiomic features improve prediction for lung cancer incidence: A nested case-control analysis of the National Lung Screening Trial. Cancer Medicine. PMID 30507033 DOI: 10.1002/cam4.1852  1
2018 Hosny A, Parmar C, Coroller TP, Grossmann P, Zeleznik R, Kumar A, Bussink J, Gillies RJ, Mak RH, Aerts HJWL. Deep learning for lung cancer prognostication: A retrospective multi-cohort radiomics study. Plos Medicine. 15: e1002711. PMID 30500819 DOI: 10.1371/journal.pmed.1002711  1
2018 Napel S, Mu W, Jardim-Perassi BV, Aerts HJWL, Gillies RJ. Quantitative imaging of cancer in the postgenomic era: Radio(geno)mics, deep learning, and habitats. Cancer. PMID 30383900 DOI: 10.1002/cncr.31630  1
2018 Kishimoto S, Oshima N, Krishna MC, Gillies RJ. Direct and indirect assessment of cancer metabolism explored by MRI. Nmr in Biomedicine. e3966. PMID 30169896 DOI: 10.1002/nbm.3966  1
2018 Persi E, Duran-Frigola M, Damaghi M, Roush WR, Aloy P, Cleveland JL, Gillies RJ, Ruppin E. Systems analysis of intracellular pH vulnerabilities for cancer therapy. Nature Communications. 9: 2997. PMID 30065243 DOI: 10.1038/s41467-018-05261-x  1
2018 Gillies RJ, Brown JS, Anderson ARA, Gatenby RA. Eco-evolutionary causes and consequences of temporal changes in intratumoural blood flow. Nature Reviews. Cancer. PMID 29891961 DOI: 10.1038/s41568-018-0030-7  1
2018 Matsumoto S, Kishimoto S, Saito K, Takakusagi Y, Munasinghe JP, Devasahayam N, Hart C, Gillies RJ, Mitchell JB, Krishna MC. Metabolic and physiologic imaging biomarkers of the tumor microenvironment predict treatment outcome with radiation or a hypoxia-activated prodrug in mice. Cancer Research. PMID 29792309 DOI: 10.1158/0008-5472.CAN-18-0491  1
2018 Gillies RJ, Balagurunathan Y. Perfusion MR Imaging of Breast Cancer: Insights Using "Habitat Imaging". Radiology. 180271. PMID 29714676 DOI: 10.1148/radiol.2018180271  1
2018 Liu Y, Kim J, Balagurunathan Y, Hawkins S, Stringfield O, Schabath MB, Li Q, Qu F, Liu S, Garcia AL, Ye Z, Gillies RJ. Prediction of pathological nodal involvement by CT-based Radiomic features of the primary tumor in patients with clinically node-negative peripheral lung adenocarcinomas. Medical Physics. PMID 29624702 DOI: 10.1002/mp.12901  1
2018 Paul R, Hawkins SH, Schabath MB, Gillies RJ, Hall LO, Goldgof DB. Predicting malignant nodules by fusing deep features with classical radiomics features. Journal of Medical Imaging (Bellingham, Wash.). 5: 011021. PMID 29594181 DOI: 10.1117/1.JMI.5.1.011021  1
2018 Damgaci S, Ibrahim-Hashim A, Enriquez-Navas PM, Pilon-Thomas S, Guvenis A, Gillies RJ. Hypoxia and Acidosis: Immune Suppressors and Therapeutic Targets. Immunology. PMID 29485185 DOI: 10.1111/imm.12917  1
2017 Tunali I, Stringfield O, Guvenis A, Wang H, Liu Y, Balagurunathan Y, Lambin P, Gillies RJ, Schabath MB. Radial gradient and radial deviation radiomic features from pre-surgical CT scans are associated with survival among lung adenocarcinoma patients. Oncotarget. 8: 96013-96026. PMID 29221183 DOI: 10.18632/oncotarget.21629  1
2017 Li Q, Balagurunathan Y, Liu Y, Qi J, Schabath MB, Ye Z, Gillies RJ. Comparison Between Radiological Semantic Features and Lung-RADS in Predicting Malignancy of Screen-Detected Lung Nodules in the National Lung Screening Trial. Clinical Lung Cancer. PMID 29137847 DOI: 10.1016/j.cllc.2017.10.002  1
2017 Li Q, Kim J, Balagurunathan Y, Qi J, Liu Y, Latifi K, Moros EG, Schabath MB, Ye Z, Gillies RJ, Dilling TJ. CT imaging features associated with recurrence in non-small cell lung cancer patients after stereotactic body radiotherapy. Radiation Oncology (London, England). 12: 158. PMID 28946909 DOI: 10.1186/s13014-017-0892-y  1
2017 Chang YC, Ackerstaff E, Tschudi Y, Jimenez B, Foltz W, Fisher C, Lilge L, Cho H, Carlin S, Gillies RJ, Balagurunathan Y, Yechieli RL, Subhawong T, Turkbey B, Pollack A, et al. Delineation of Tumor Habitats based on Dynamic Contrast Enhanced MRI. Scientific Reports. 7: 9746. PMID 28851989 DOI: 10.1038/s41598-017-09932-5  1
2017 Liu Y, Wang H, Li Q, McGettigan MJ, Balagurunathan Y, Garcia AL, Thompson ZJ, Heine JJ, Ye Z, Gillies RJ, Schabath MB. Radiologic Features of Small Pulmonary Nodules and Lung Cancer Risk in the National Lung Screening Trial: A Nested Case-Control Study. Radiology. 161458. PMID 28837413 DOI: 10.1148/radiol.2017161458  1
2017 Grossmann P, Stringfield O, El-Hachem N, Bui MM, Rios Velazquez E, Parmar C, Leijenaar RT, Haibe-Kains B, Lambin P, Gillies R, Aerts HJ. Defining the biological basis of radiomic phenotypes in lung cancer. Elife. 6. PMID 28731408 DOI: 10.7554/eLife.23421  1
2017 Yip SSF, Liu Y, Parmar C, Li Q, Liu S, Qu F, Ye Z, Gillies RJ, Aerts HJWL. Associations between radiologist-defined semantic and automatically computed radiomic features in non-small cell lung cancer. Scientific Reports. 7: 3519. PMID 28615677 DOI: 10.1038/s41598-017-02425-5  1
2017 Rios Velazquez E, Parmar C, Liu Y, Coroller TP, Cruz G, Stringfield O, Ye Z, Makrigiorgos GM, Fennessy FMM, Mak RH, Gillies RJ, Quackenbush J, Aerts H. Somatic mutations drive distinct imaging phenotypes in lung cancer. Cancer Research. PMID 28566328 DOI: 10.1158/0008-5472.CAN-17-0122  1
2017 Ibrahim-Hashim A, Abrahams D, Enriquez-Navas PM, Luddy K, Gatenby RA, Gillies RJ. Tris-base buffer: a promising new inhibitor for cancer progression and metastasis. Cancer Medicine. PMID 28556628 DOI: 10.1002/cam4.1032  1
2017 Li Q, Kim J, Balagurunathan Y, Liu Y, Latifi K, Stringfield O, Garcia A, Moros EG, Dilling TJ, Schabath MB, Ye Z, Gillies RJ. Imaging features from pre-treatment CT scans are associated with clinical outcomes in non-small-cell lung cancer patients treated with stereotactic body radiotherapy. Medical Physics. PMID 28464316 DOI: 10.1002/mp.12309  1
2017 Silva AS, Silva MD, Sudalagunta P, Distler AI, Jacobson T, Collins A, Nguyen T, Song J, Chen DT, Chen L, Cubitt CL, Baz R, Perez L, Rebatchouk D, Dalton W, ... ... Gillies RJ, et al. An ex vivo platform for the prediction of clinical response in multiple myeloma. Cancer Research. PMID 28400475 DOI: 10.1158/0008-5472.CAN-17-0502  1
2017 Ibrahim-Hashim A, Robertson-Tessi M, Enrizues-Navas P, Damaghi M, Balagurunathan Y, Wojtkowiak JW, Russell S, Yoonseok K, Lloyd MC, Bui MM, Brown JS, Anderson AR, Gillies RJ, Gatenby RA. Defining cancer subpopulations by adaptive strategies rather than molecular properties provides novel insights into intratumoral evolution. Cancer Research. PMID 28249898 DOI: 10.1158/0008-5472.CAN-16-2844  1
2017 Beichel RR, Smith BJ, Bauer C, Ulrich EJ, Ahmadvand P, Budzevich MM, Gillies RJ, Goldgof D, Grkovski M, Hamarneh G, Huang Q, Kinahan PE, Laymon CM, Mountz JM, Muzi JP, et al. Multi-site quality and variability analysis of 3D FDG PET segmentations based on phantom and clinical image data. Medical Physics. 44: 479-496. PMID 28205306 DOI: 10.1002/mp.12041  1
2016 Cherezov D, Hawkins S, Goldgof D, Hall L, Balagurunathan Y, Gillies RJ, Schabath MB. Improving malignancy prediction through feature selection informed by nodule size ranges in NLST. Conference Proceedings. Ieee International Conference On Systems, Man, and Cybernetics. 2016: 001939-1944. PMID 30473607 DOI: 10.1109/SMC.2016.7844523  1
2016 Stoyanova R, Takhar M, Tschudi Y, Ford JC, Solórzano G, Erho N, Balagurunathan Y, Punnen S, Davicioni E, Gillies RJ, Pollack A. Prostate cancer radiomics and the promise of radiogenomics. Translational Cancer Research. 5: 432-447. PMID 29188191  1
2016 Paul R, Hawkins SH, Balagurunathan Y, Schabath MB, Gillies RJ, Hall LO, Goldgof DB. Deep Feature Transfer Learning in Combination with Traditional Features Predicts Survival Among Patients with Lung Adenocarcinoma. Tomography : a Journal For Imaging Research. 2: 388-395. PMID 28066809 DOI: 10.18383/j.tom.2016.00211  1
2016 Avnet S, Di Pompo G, Chano T, Errani C, Ibrahim-Hashim A, Gillies RJ, Donati DM, Baldini N. Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB acivation. International Journal of Cancer. PMID 27888521 DOI: 10.1002/ijc.30540  1
2016 Wang H, Schabath MB, Liu Y, Han Y, Li Q, Gillies RJ, Ye Z. Clinical and CT characteristics of surgically resected lung adenocarcinomas harboring ALK rearrangements or EGFR mutations. European Journal of Radiology. 85: 1934-1940. PMID 27776643 DOI: 10.1016/j.ejrad.2016.08.023  1
2016 O'Connor JP, Aboagye EO, Adams JE, Aerts HJ, Barrington SF, Beer AJ, Boellaard R, Bohndiek SE, Brady M, Brown G, Buckley DL, Chenevert TL, Clarke LP, Collette S, Cook GJ, ... ... Gillies RJ, et al. Imaging biomarker roadmap for cancer studies. Nature Reviews. Clinical Oncology. PMID 27725679 DOI: 10.1038/nrclinonc.2016.162  1
2016 Zhou M, Chaudhury B, Hall LO, Goldgof DB, Gillies RJ, Gatenby RA. Identifying spatial imaging biomarkers of glioblastoma multiforme for survival group prediction. Journal of Magnetic Resonance Imaging : Jmri. PMID 27678245 DOI: 10.1002/jmri.25497  1
2016 Liu Y, Balagurunathan Y, Atwater T, Antic S, Li Q, Walker RC, Smith G, Massion PP, Schabath MB, Gillies RJ. Radiological Image traits Predictive of Cancer Status in Pulmonary Nodules. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27663588 DOI: 10.1158/1078-0432.CCR-15-3102  1
2016 Schabath MB, Massion PP, Thompson ZJ, Eschrich SA, Balagurunathan Y, Goldof D, Aberle DR, Gillies RJ. Differences in Patient Outcomes of Prevalence, Interval, and Screen-Detected Lung Cancers in the CT Arm of the National Lung Screening Trial. Plos One. 11: e0159880. PMID 27509046 DOI: 10.1371/journal.pone.0159880  1
2016 Stoyanova R, Pollack A, Takhar M, Lynne C, Parra N, Lam LL, Alshalalfa M, Buerki C, Castillo R, Jorda M, Ashab HA, Kryvenko ON, Punnen S, Parekh DJ, Abramowitz MC, ... Gillies RJ, et al. Association of multiparametric MRI quantitative imaging features with prostate cancer gene expression in MRI-targeted prostate biopsies. Oncotarget. PMID 27438142 DOI: 10.18632/oncotarget.10523  1
2016 Hawkins S, Wang H, Liu Y, Garcia A, Stringfield O, Krewer H, Li Q, Cherezov D, Gatenby RA, Balagurunathan Y, Goldgof D, Schabath MB, Hall L, Gillies RJ. Predicting malignant nodules from screening CTs. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 27422797 DOI: 10.1016/j.jtho.2016.07.002  1
2016 Athelogou M, Kim HJ, Dima A, Obuchowski N, Peskin A, Gavrielides MA, Petrick N, Saiprasad G, Colditz Colditz D, Beaumont H, Oubel E, Tan Y, Zhao B, Kuhnigk JM, Moltz JH, ... ... Gillies RJ, et al. Algorithm Variability in the Estimation of Lung Nodule Volume From Phantom CT Scans: Results of the QIBA 3A Public Challenge. Academic Radiology. PMID 27215408 DOI: 10.1016/j.acra.2016.02.018  1
2016 Huang X, Xiao X, Gillies RJ, Tian H. Design and automated production of 11C-alpha-methyl-l-tryptophan (11C-AMT). Nuclear Medicine and Biology. 43: 303-8. PMID 27150033 DOI: 10.1016/j.nucmedbio.2016.02.001  1
2016 Damaghi M, Gillies RJ. Lysosomal Protein Relocation as an Adaptation Mechanism to Extracellular Acidosis. Cell Cycle (Georgetown, Tex.). 0. PMID 27097301 DOI: 10.1080/15384101.2016.1176394  1
2016 Liu Y, Kim J, Balagurunathan Y, Li Q, Garcia AL, Stringfield O, Ye Z, Gillies RJ. Radiomic Features Are Associated With EGFR Mutation Status in Lung Adenocarcinomas. Clinical Lung Cancer. PMID 27017476 DOI: 10.1016/j.cllc.2016.02.001  1
2016 Lloyd MC, Cunningham JJ, Bui MM, Gillies RJ, Brown JS, Gatenby RA. Darwinian dynamics of intratumoral heterogeneity: not solely random mutations but also variable environmental selection forces. Cancer Research. PMID 27009166 DOI: 10.1158/0008-5472.CAN-15-2962  1
2016 Liu Y, Kim J, Qu F, Liu S, Wang H, Balagurunathan Y, Ye Z, Gillies RJ. CT Features Associated with Epidermal Growth Factor Receptor Mutation Status in Patients with Lung Adenocarcinoma. Radiology. 151455. PMID 26937803 DOI: 10.1148/radiol.2016151455  1
2016 Enriquez-Navas PM, Kam Y, Das T, Hassan S, Silva A, Foroutan P, Ruiz E, Martinez G, Minton S, Gillies RJ, Gatenby RA. Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer. Science Translational Medicine. 8: 327ra24. PMID 26912903 DOI: 10.1126/scitranslmed.aad7842  1
2016 Yankeelov TE, Mankoff DA, Schwartz LH, Lieberman FS, Buatti JM, Mountz JM, Erickson BJ, Fennessy FM, Huang W, Kalpathy-Cramer J, Wahl RL, Linden HM, Kinahan PE, Zhao B, Hylton NM, ... Gillies RJ, et al. Quantitative Imaging in Cancer Clinical Trials. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 22: 284-90. PMID 26773162 DOI: 10.1158/1078-0432.CCR-14-3336  1
2015 Pilon-Thomas S, Kodumudi KN, El-Kenawi AE, Russell S, Weber AM, Luddy K, Damaghi M, Wojtkowiak JW, Mulé JJ, Ibrahim-Hashim A, Gillies RJ. Neutralization of tumor acidity improves antitumor responses to immunotherapeutic interventions. Cancer Research. PMID 26719539 DOI: 10.1158/0008-5472.CAN-15-1743  1
2015 Wang H, Schabath MB, Liu Y, Stringfield O, Balagurunathan Y, Heine JJ, Eschrich SA, Ye Z, Gillies RJ. Association Between Computed Tomographic Features and Kirsten Rat Sarcoma Viral Oncogene Mutations in Patients With Stage I Lung Adenocarcinoma and Their Prognostic Value. Clinical Lung Cancer. PMID 26712103 DOI: 10.1016/j.cllc.2015.11.002  1
2015 Damaghi M, Tafreshi NK, Lloyd MC, Sprung R, Estrella V, Wojtkowiak JW, Morse DL, Koomen JM, Bui MM, Gatenby RA, Gillies RJ. Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane. Nature Communications. 6: 8752. PMID 26658462 DOI: 10.1038/ncomms9752  1
2015 Gillies RJ, Kinahan PE, Hricak H. Radiomics: Images Are More than Pictures, They Are Data. Radiology. 151169. PMID 26579733 DOI: 10.1148/radiol.2015151169  1
2015 Schabath MB, Gillies RJ. Noninvasive Quantitative Imaging-based Biomarkers and Lung Cancer Screening. American Journal of Respiratory and Critical Care Medicine. 192: 654-6. PMID 26371810 DOI: 10.1164/rccm.201506-1160ED  1
2015 Stephen RM, Jha AK, Roe DJ, Trouard TP, Galons JP, Kupinski MA, Frey G, Cui H, Squire S, Pagel MD, Rodriguez JJ, Gillies RJ, Stopeck AT. Diffusion MRI with Semi-Automated Segmentation Can Serve as a Restricted Predictive Biomarker of the Therapeutic Response of Liver Metastasis. Magnetic Resonance Imaging. PMID 26284600 DOI: 10.1016/j.mri.2015.08.006  1
2015 Tafreshi NK, Lloyd MC, Proemsey JB, Bui MM, Kim J, Gillies RJ, Morse DL. Evaluation of CAIX and CAXII Expression in Breast Cancer at Varied O2 Levels: CAIX is the Superior Surrogate Imaging Biomarker of Tumor Hypoxia. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 26276155 DOI: 10.1007/s11307-015-0885-x  1
2015 Leijenaar RT, Nalbantov G, Carvalho S, van Elmpt WJ, Troost EG, Boellaard R, Aerts HJ, Gillies RJ, Lambin P. The effect of SUV discretization in quantitative FDG-PET Radiomics: the need for standardized methodology in tumor texture analysis. Scientific Reports. 5: 11075. PMID 26242464 DOI: 10.1038/srep11075  1
2015 Rajeshkumar NV, Dutta P, Yabuuchi S, de Wilde RF, Matrinez GV, Le A, Kamphorst JJ, Rabinowitz JD, Jain SK, Hidalgo M, Dang CV, Gillies RJ, Maitra A. Therapeutic targeting of the Warburg effect in pancreatic cancer relies on an absence of p53 function. Cancer Research. PMID 26113084 DOI: 10.1158/0008-5472.CAN-15-0108  1
2015 Wang H, Schabath MB, Liu Y, Berglund AE, Bloom GC, Kim J, Stringfield O, Eikman EA, Klippenstein DL, Heine JJ, Eschrich SA, Ye Z, Gillies RJ. Semiquantitative Computed Tomography Characteristics for Lung Adenocarcinoma and Their Association With Lung Cancer Survival. Clinical Lung Cancer. PMID 26077095 DOI: 10.1016/j.cllc.2015.05.007  1
2015 Chaudhury B, Zhou M, Goldgof DB, Hall LO, Gatenby RA, Gillies RJ, Patel BK, Weinfurtner RJ, Drukteinis JS. Heterogeneity in intratumoral regions with rapid gadolinium washout correlates with estrogen receptor status and nodal metastasis. Journal of Magnetic Resonance Imaging : Jmri. PMID 25884277 DOI: 10.1002/jmri.24921  1
2015 Robertson-Tessi M, Gillies RJ, Gatenby RA, Anderson AR. Impact of metabolic heterogeneity on tumor growth, invasion, and treatment outcomes. Cancer Research. 75: 1567-79. PMID 25878146 DOI: 10.1158/0008-5472.CAN-14-1428  1
2015 Gillies RJ, Gatenby RA. Metabolism and its sequelae in cancer evolution and therapy. Cancer Journal (Sudbury, Mass.). 21: 88-96. PMID 25815848 DOI: 10.1097/PPO.0000000000000102  1
2015 Verduzco D, Lloyd M, Xu L, Ibrahim-Hashim A, Balagurunathan Y, Gatenby RA, Gillies RJ. Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance. Plos One. 10: e0120958. PMID 25811878 DOI: 10.1371/journal.pone.0120958  1
2015 Grove O, Berglund AE, Schabath MB, Aerts HJ, Dekker A, Wang H, Velazquez ER, Lambin P, Gu Y, Balagurunathan Y, Eikman E, Gatenby RA, Eschrich S, Gillies RJ. Quantitative computed tomographic descriptors associate tumor shape complexity and intratumor heterogeneity with prognosis in lung adenocarcinoma. Plos One. 10: e0118261. PMID 25739030 DOI: 10.1371/journal.pone.0118261  1
2015 Huang X, Gillies RJ, Tian H. Synthesis of [(18) F] 4-amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide (IDO5L): a novel potential PET probe for imaging of IDO1 expression. Journal of Labelled Compounds & Radiopharmaceuticals. 58: 156-62. PMID 25690452 DOI: 10.1002/jlcr.3263  1
2015 Wojtkowiak JW, Cornnell HC, Matsumoto S, Saito K, Takakusagi Y, Dutta P, Kim M, Zhang X, Leos R, Bailey KM, Martinez G, Lloyd MC, Weber C, Mitchell JB, Lynch RM, ... ... Gillies RJ, et al. Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302. Cancer & Metabolism. 3: 2. PMID 25635223 DOI: 10.1186/s40170-014-0026-z  1
2015 Kam Y, Das T, Tian H, Foroutan P, Ruiz E, Martinez G, Minton S, Gillies RJ, Gatenby RA. Sweat but no gain: inhibiting proliferation of multidrug resistant cancer cells with "ersatzdroges". International Journal of Cancer. Journal International Du Cancer. 136: E188-96. PMID 25156304 DOI: 10.1002/ijc.29158  1
2015 Obuchowski NA, Reeves AP, Huang EP, Wang XF, Buckler AJ, Kim HJ, Barnhart HX, Jackson EF, Giger ML, Pennello G, Toledano AY, Kalpathy-Cramer J, Apanasovich TV, Kinahan PE, Myers KJ, ... ... Gillies RJ, et al. Quantitative imaging biomarkers: a review of statistical methods for computer algorithm comparisons. Statistical Methods in Medical Research. 24: 68-106. PMID 24919829 DOI: 10.1177/0962280214537390  1
2015 Farhidzadeh H, Chaudhury B, Zhou M, Goldgof DB, Hall LO, Gatenby RA, Gillies RJ, Raghavan M. Prediction of treatment outcome in soft tissue sarcoma based on radiologically defined habitats Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9414. DOI: 10.1117/12.2082324  1
2015 Chaudhury B, Zhou M, Goldgof DB, Hall LO, Gatenby RA, Gillies RJ, Drukteinis JS. Identifying metastatic breast tumors using textural kinetic features of a contrast based habitat in DCE-MRI Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9414. DOI: 10.1117/12.2081386  1
2015 Zhou M, Hall LO, Goldgof DB, Gillies RJ, Gatenby RA. Imbalanced learning for clinical survival group prediction of brain tumor patients Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9414. DOI: 10.1117/12.2075606  1
2015 Zhou M, Hall LO, Goldgof DB, Russo R, Gillies RJ, Gatenby RA. Decoding brain cancer dynamics: A quantitative histogram-based approach using temporal MRI Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9414. DOI: 10.1117/12.2075545  1
2015 Tafreshi NK, Lloyd MC, Proemsey JB, Bui MM, Kim J, Gillies RJ, Morse DL. Evaluation of CAIX and CAXII Expression in Breast Cancer at Varied O2 Levels: CAIX is the Superior Surrogate Imaging Biomarker of Tumor Hypoxia Molecular Imaging and Biology. DOI: 10.1007/s11307-015-0885-x  1
2014 Dutta P, Martinez GV, Gillies RJ. Nanodiamond as a New Hyperpolarizing Agent and Its (13)C MRS. The Journal of Physical Chemistry Letters. 5: 597-600. PMID 26276615 DOI: 10.1021/jz402659t  1
2014 Bailey KM, Cornnell HH, Ibrahim-Hashim A, Wojtkowiak JW, Hart CP, Zhang X, Leos R, Martinez GV, Baker AF, Gillies RJ. Evaluation of the "steal" phenomenon on the efficacy of hypoxia activated prodrug TH-302 in pancreatic cancer. Plos One. 9: e113586. PMID 25532146 DOI: 10.1371/journal.pone.0113586  1
2014 Fernandes SM, Lee YS, Gillies RJ, Hruby VJ. Synthesis and evaluation of bivalent ligands for binding to the human melanocortin-4 receptor. Bioorganic & Medicinal Chemistry. 22: 6360-5. PMID 25438759 DOI: 10.1016/j.bmc.2014.09.055  1
2014 Takakusagi Y, Matsumoto S, Saito K, Matsuo M, Kishimoto S, Wojtkowiak JW, DeGraff W, Kesarwala AH, Choudhuri R, Devasahayam N, Subramanian S, Munasinghe JP, Gillies RJ, Mitchell JB, Hart CP, et al. Pyruvate induces transient tumor hypoxia by enhancing mitochondrial oxygen consumption and potentiates the anti-tumor effect of a hypoxia-activated prodrug TH-302. Plos One. 9: e107995. PMID 25254649 DOI: 10.1371/journal.pone.0107995  1
2014 Balagurunathan Y, Kumar V, Gu Y, Kim J, Wang H, Liu Y, Goldgof DB, Hall LO, Korn R, Zhao B, Schwartz LH, Basu S, Eschrich S, Gatenby RA, Gillies RJ. Test-retest reproducibility analysis of lung CT image features. Journal of Digital Imaging. 27: 805-23. PMID 24990346 DOI: 10.1007/s10278-014-9716-x  1
2014 Epstein T, Xu L, Gillies RJ, Gatenby RA. Separation of metabolic supply and demand: aerobic glycolysis as a normal physiological response to fluctuating energetic demands in the membrane. Cancer & Metabolism. 2: 7. PMID 24982758 DOI: 10.1186/2049-3002-2-7  1
2014 Aerts HJ, Velazquez ER, Leijenaar RT, Parmar C, Grossmann P, Carvalho S, Cavalho S, Bussink J, Monshouwer R, Haibe-Kains B, Rietveld D, Hoebers F, Rietbergen MM, Leemans CR, Dekker A, ... ... Gillies RJ, et al. Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach. Nature Communications. 5: 4006. PMID 24892406 DOI: 10.1038/ncomms5006  1
2014 Mountz JM, Yankeelov TE, Rubin DL, Buatti JM, Erikson BJ, Fennessy FM, Gillies RJ, Huang W, Jacobs MA, Kinahan PE, Laymon CM, Linden HM, Mankoff DA, Schwartz LH, Shim H, et al. Letter to cancer center directors: Progress in quantitative imaging as a means to predict and/or measure tumor response in cancer therapy trials. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 2115-6. PMID 24868025 DOI: 10.1200/JCO.2014.55.8866  1
2014 Bailey KM, Wojtkowiak JW, Cornnell HH, Ribeiro MC, Balagurunathan Y, Hashim AI, Gillies RJ. Mechanisms of buffer therapy resistance. Neoplasia (New York, N.Y.). 16: 354-64.e1-3. PMID 24862761 DOI: 10.1016/j.neo.2014.04.005  1
2014 Balagurunathan Y, Gu Y, Wang H, Kumar V, Grove O, Hawkins S, Kim J, Goldgof DB, Hall LO, Gatenby RA, Gillies RJ. Reproducibility and Prognosis of Quantitative Features Extracted from CT Images. Translational Oncology. 7: 72-87. PMID 24772210 DOI: 10.1593/tlo.13844  1
2014 Lloyd MC, Alfarouk KO, Verduzco D, Bui MM, Gillies RJ, Ibrahim ME, Brown JS, Gatenby RA. Vascular measurements correlate with estrogen receptor status. Bmc Cancer. 14: 279. PMID 24755315 DOI: 10.1186/1471-2407-14-279  1
2014 Zhang X, Pagel MD, Baker AF, Gillies RJ. Reproducibility of magnetic resonance perfusion imaging. Plos One. 9: e89797. PMID 24587040 DOI: 10.1371/journal.pone.0089797  1
2014 Khramtsov VV, Gillies RJ. Janus-faced tumor microenvironment and redox. Antioxidants & Redox Signaling. 21: 723-9. PMID 24512276 DOI: 10.1089/ars.2014.5864  1
2014 Oosterwijk E, Gillies RJ. Targeting ion transport in cancer. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20130107. PMID 24493755 DOI: 10.1098/rstb.2013.0107  1
2014 Mignion L, Dutta P, Martinez GV, Foroutan P, Gillies RJ, Jordan BF. Monitoring chemotherapeutic response by hyperpolarized 13C-fumarate MRS and diffusion MRI. Cancer Research. 74: 686-94. PMID 24285723 DOI: 10.1158/0008-5472.CAN-13-1914  1
2014 Luhach I, Idiyatullin D, Lynch CC, Corum C, Martinez GV, Garwood M, Gillies RJ. Rapid ex vivo imaging of PAIII prostate to bone tumor with SWIFT-MRI. Magnetic Resonance in Medicine. 72: 858-63. PMID 24155275 DOI: 10.1002/mrm.24979  1
2014 Tafreshi NK, Lloyd MC, Bui MM, Gillies RJ, Morse DL. Carbonic anhydrase IX as an imaging and therapeutic target for tumors and metastases. Sub-Cellular Biochemistry. 75: 221-54. PMID 24146382 DOI: 10.1007/978-94-007-7359-2_12  1
2014 Chaudhury B, Zhou M, Goldgof DB, Hall LO, Gatenby RA, Gillies RJ, Drukteinis JS. Using features from tumor subregions of breast DCE-MRI for estrogen receptor status prediction Conference Proceedings - Ieee International Conference On Systems, Man and Cybernetics. 2014: 2624-2629. DOI: 10.1109/smc.2014.6974323  1
2014 Zhou M, Hall LO, Goldgof DB, Gillies RJ, Gatenby RA. Exploring brain tumor heterogeneity for survival time prediction Proceedings - International Conference On Pattern Recognition. 580-585. DOI: 10.1109/ICPR.2014.110  1
2014 Hawkins SH, Korecki JN, Balagurunathan Y, Gu Y, Kumar V, Basu S, Hall LO, Goldgof DB, Gatenby RA, Gillies RJ. Predicting outcomes of nonsmall cell lung cancer using CT image features Ieee Access. 2: 1418-1426. DOI: 10.1109/ACCESS.2014.2373335  1
2014 Dutta P, Martinez GV, Gillies RJ. Nanodiamond as a new hyperpolarizing agent and its 13C MRS Journal of Physical Chemistry Letters. 5: 597-600. DOI: 10.1021/jz402659t  1
2013 Dutta P, Martinez GV, Gillies RJ. A New Horizon of DNP technology: Application to In-vivo (13)C Magnetic Resonance Spectroscopy and Imaging. Biophysical Reviews. 5: 271-281. PMID 26491489 DOI: 10.1007/s12551-012-0099-2  1
2013 Damaghi M, Wojtkowiak JW, Gillies RJ. pH sensing and regulation in cancer. Frontiers in Physiology. 4: 370. PMID 24381558 DOI: 10.3389/fphys.2013.00370  1
2013 Foroutan P, Kreahling JM, Morse DL, Grove O, Lloyd MC, Reed D, Raghavan M, Altiok S, Martinez GV, Gillies RJ. Diffusion MRI and novel texture analysis in osteosarcoma xenotransplants predicts response to anti-checkpoint therapy. Plos One. 8: e82875. PMID 24358232 DOI: 10.1371/journal.pone.0082875  1
2013 Kim M, Gillies RJ, Rejniak KA. Current advances in mathematical modeling of anti-cancer drug penetration into tumor tissues. Frontiers in Oncology. 3: 278. PMID 24303366 DOI: 10.3389/fonc.2013.00278  1
2013 Rothberg JM, Bailey KM, Wojtkowiak JW, Ben-Nun Y, Bogyo M, Weber E, Moin K, Blum G, Mattingly RR, Gillies RJ, Sloane BF. Acid-mediated tumor proteolysis: contribution of cysteine cathepsins. Neoplasia (New York, N.Y.). 15: 1125-37. PMID 24204192 DOI: 10.1593/neo.13946  1
2013 Gatenby RA, Grove O, Gillies RJ. Quantitative imaging in cancer evolution and ecology. Radiology. 269: 8-15. PMID 24062559 DOI: 10.1148/radiol.13122697  1
2013 Leijenaar RT, Carvalho S, Velazquez ER, van Elmpt WJ, Parmar C, Hoekstra OS, Hoekstra CJ, Boellaard R, Dekker AL, Gillies RJ, Aerts HJ, Lambin P. Stability of FDG-PET Radiomics features: an integrated analysis of test-retest and inter-observer variability. Acta Oncologica (Stockholm, Sweden). 52: 1391-7. PMID 24047337 DOI: 10.3109/0284186X.2013.812798  1
2013 Alleti R, Vagner J, Dehigaspitiya DC, Moberg VE, Elshan NG, Tafreshi NK, Brabez N, Weber CS, Lynch RM, Hruby VJ, Gillies RJ, Morse DL, Mash EA. Synthesis and characterization of time-resolved fluorescence probes for evaluation of competitive binding to melanocortin receptors. Bioorganic & Medicinal Chemistry. 21: 5029-38. PMID 23890524 DOI: 10.1016/j.bmc.2013.06.052  1
2013 Barkey NM, Preihs C, Cornnell HH, Martinez G, Carie A, Vagner J, Xu L, Lloyd MC, Lynch VM, Hruby VJ, Sessler JL, Sill KN, Gillies RJ, Morse DL. Development and in vivo quantitative magnetic resonance imaging of polymer micelles targeted to the melanocortin 1 receptor. Journal of Medicinal Chemistry. 56: 6330-8. PMID 23863078 DOI: 10.1021/jm4005576  1
2013 Dutta P, Le A, Vander Jagt DL, Tsukamoto T, Martinez GV, Dang CV, Gillies RJ. Evaluation of LDH-A and glutaminase inhibition in vivo by hyperpolarized 13C-pyruvate magnetic resonance spectroscopy of tumors. Cancer Research. 73: 4190-5. PMID 23722553 DOI: 10.1158/0008-5472.CAN-13-0465  1
2013 Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC, Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, ... ... Gillies RJ, et al. A physical sciences network characterization of non-tumorigenic and metastatic cells. Scientific Reports. 3: 1449. PMID 23618955 DOI: 10.1038/srep01449  1
2013 Kreahling JM, Foroutan P, Reed D, Martinez G, Razabdouski T, Bui MM, Raghavan M, Letson D, Gillies RJ, Altiok S. Wee1 inhibition by MK-1775 leads to tumor inhibition and enhances efficacy of gemcitabine in human sarcomas. Plos One. 8: e57523. PMID 23520471 DOI: 10.1371/journal.pone.0057523  1
2013 Brabez N, Nguyen KL, Saunders K, Lacy R, Xu L, Gillies RJ, Lynch RM, Chassaing G, Lavielle S, Hruby VJ. Synthesis and evaluation of cholecystokinin trimers: a multivalent approach to pancreatic cancer detection and treatment. Bioorganic & Medicinal Chemistry Letters. 23: 2422-5. PMID 23489620 DOI: 10.1016/j.bmcl.2013.02.022  1
2013 Martinez GV, Navath S, Sewda K, Rao V, Foroutan P, Alleti R, Moberg VE, Ahad AM, Coppola D, Lloyd MC, Gillies RJ, Morse DL, Mash EA. Demonstration of a sucrose-derived contrast agent for magnetic resonance imaging of the GI tract. Bioorganic & Medicinal Chemistry Letters. 23: 2061-4. PMID 23481651 DOI: 10.1016/j.bmcl.2013.02.008  1
2013 Gu Y, Kumar V, Hall LO, Goldgof DB, Li CY, Korn R, Bendtsen C, Velazquez ER, Dekker A, Aerts H, Lambin P, Li X, Tian J, Gatenby RA, Gillies RJ. Automated Delineation of Lung Tumors from CT Images Using a Single Click Ensemble Segmentation Approach. Pattern Recognition. 46: 692-702. PMID 23459617 DOI: 10.1016/j.patcog.2012.10.005  1
2013 Kumar V, Nath K, Berman CG, Kim J, Tanvetyanon T, Chiappori AA, Gatenby RA, Gillies RJ, Eikman EA. Variance of SUVs for FDG-PET/CT is greater in clinical practice than under ideal study settings. Clinical Nuclear Medicine. 38: 175-82. PMID 23354032 DOI: 10.1097/RLU.0b013e318279ffdf  1
2013 Estrella V, Chen T, Lloyd M, Wojtkowiak J, Cornnell HH, Ibrahim-Hashim A, Bailey K, Balagurunathan Y, Rothberg JM, Sloane BF, Johnson J, Gatenby RA, Gillies RJ. Acidity generated by the tumor microenvironment drives local invasion. Cancer Research. 73: 1524-35. PMID 23288510 DOI: 10.1158/0008-5472.CAN-12-2796  1
2013 Martinez-Zaguilan R, Tompkins LS, Gillies RJ, Lynch RM. Simultaneous analysis of intracellular pH and Ca²⁺ from cell populations. Methods in Molecular Biology (Clifton, N.J.). 937: 253-71. PMID 23007592 DOI: 10.1007/978-1-62703-086-1_16  1
2013 Zhou M, Hall LO, Goldgof DB, Gillies RJ, Gatenby RA. Survival time prediction of patients with glioblastoma multiforme tumors using spatial distance measurement Proceedings of Spie - the International Society For Optical Engineering. 8670. DOI: 10.1117/12.2007699  1
2013 Krewer H, Geiger B, Hall LO, Goldgof DB, Gu Y, Tockman M, Gillies RJ. Effect of texture features in computer aided diagnosis of pulmonary nodules in low-dose computed tomography Proceedings - 2013 Ieee International Conference On Systems, Man, and Cybernetics, Smc 2013. 3887-3891. DOI: 10.1109/SMC.2013.663  1
2013 Dutta P, Martinez GV, Gillies RJ. A new horizon of DNP technology: Application to in-vivo 13C magnetic resonance spectroscopy and imaging Biophysical Reviews. 5: 271-281. DOI: 10.1007/s12551-012-0099-2  1
2013 Martinez-Zaguilan R, Tompkins LS, Gillies RJ, Lynch RM. Simultaneous analysis of intracellular pH and Ca2+ from cell populations Methods in Molecular Biology. 937: 253-271. DOI: 10.1007/978-1-62703-86-1_16  1
2012 Ribeiro MD, Silva AS, Bailey KM, Kumar NB, Sellers TA, Gatenby RA, Ibrahim-Hashim A, Gillies RJ. Buffer Therapy for Cancer. Journal of Nutrition & Food Sciences. 2: 6. PMID 24371544  1
2012 Stephen RM, Pagel MD, Brown K, Baker AF, Meuillet EJ, Gillies RJ. Monitoring the development of xenograft triple-negative breast cancer models using diffusion-weighted magnetic resonance imaging. Experimental Biology and Medicine (Maywood, N.J.). 237: 1273-80. PMID 23239438 DOI: 10.1258/ebm.2012.011326  1
2012 Xu L, Josan JS, Vagner J, Caplan MR, Hruby VJ, Mash EA, Lynch RM, Morse DL, Gillies RJ. Heterobivalent ligands target cell-surface receptor combinations in vivo. Proceedings of the National Academy of Sciences of the United States of America. 109: 21295-300. PMID 23236171 DOI: 10.1073/pnas.1211762109  1
2012 Rios Velazquez E, Aerts HJ, Gu Y, Goldgof DB, De Ruysscher D, Dekker A, Korn R, Gillies RJ, Lambin P. A semiautomatic CT-based ensemble segmentation of lung tumors: comparison with oncologists' delineations and with the surgical specimen. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 105: 167-73. PMID 23157978 DOI: 10.1016/j.radonc.2012.09.023  1
2012 Gillies RJ, Flowers CI, Drukteinis JS, Gatenby RA. A unifying theory of carcinogenesis, and why targeted therapy doesn't work. European Journal of Radiology. 81: S48-50. PMID 23083599 DOI: 10.1016/S0720-048X(12)70018-9  1
2012 Tafreshi NK, Gillies RJ, Morse DL. Molecular imaging of breast cancer lymph node metastasis. European Journal of Radiology. 81: S160-1. PMID 23083574 DOI: 10.1016/S0720-048X(12)70067-0  1
2012 Silva AS, Kam Y, Khin ZP, Minton SE, Gillies RJ, Gatenby RA. Evolutionary approaches to prolong progression-free survival in breast cancer. Cancer Research. 72: 6362-70. PMID 23066036 DOI: 10.1158/0008-5472.CAN-12-2235  1
2012 Bailey KM, Wojtkowiak JW, Hashim AI, Gillies RJ. Targeting the metabolic microenvironment of tumors. Advances in Pharmacology (San Diego, Calif.). 65: 63-107. PMID 22959024 DOI: 10.1016/B978-0-12-397927-8.00004-X  1
2012 Kumar V, Gu Y, Basu S, Berglund A, Eschrich SA, Schabath MB, Forster K, Aerts HJ, Dekker A, Fenstermacher D, Goldgof DB, Hall LO, Lambin P, Balagurunathan Y, Gatenby RA, ... Gillies RJ, et al. Radiomics: the process and the challenges. Magnetic Resonance Imaging. 30: 1234-48. PMID 22898692 DOI: 10.1016/j.mri.2012.06.010  1
2012 Wojtkowiak JW, Gillies RJ. Autophagy on acid. Autophagy. 8: 1688-9. PMID 22874557 DOI: 10.4161/auto.21501  1
2012 Wojtkowiak JW, Rothberg JM, Kumar V, Schramm KJ, Haller E, Proemsey JB, Lloyd MC, Sloane BF, Gillies RJ. Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments. Cancer Research. 72: 3938-47. PMID 22719070 DOI: 10.1158/0008-5472.CAN-11-3881  1
2012 Ibrahim-Hashim A, Cornnell HH, Abrahams D, Lloyd M, Bui M, Gillies RJ, Gatenby RA. Systemic buffers inhibit carcinogenesis in TRAMP mice. The Journal of Urology. 188: 624-31. PMID 22704445 DOI: 10.1016/j.juro.2012.03.113  1
2012 Gillies RJ, Verduzco D, Gatenby RA. Evolutionary dynamics of carcinogenesis and why targeted therapy does not work. Nature Reviews. Cancer. 12: 487-93. PMID 22695393 DOI: 10.1038/nrc3298  1
2012 Cárdenas-Rodríguez J, Li Y, Galons JP, Cornnell H, Gillies RJ, Pagel MD, Baker AF. Imaging biomarkers to monitor response to the hypoxia-activated prodrug TH-302 in the MiaPaCa2 flank xenograft model. Magnetic Resonance Imaging. 30: 1002-9. PMID 22554971 DOI: 10.1016/j.mri.2012.02.015  1
2012 D'Silva L, Pola A, Dutta P, Martinez GV, Sprenger P, Gillies RJ, Kuchel PW, Sendhil Velan S. Slow relaxation of longitudinal multispin orders in weakly and strongly coupled two-spin systems. Magnetic Resonance in Chemistry : Mrc. 50: 443-8. PMID 22552892 DOI: 10.1002/mrc.3820  1
2012 Martin NK, Robey IF, Gaffney EA, Gillies RJ, Gatenby RA, Maini PK. Predicting the safety and efficacy of buffer therapy to raise tumour pHe: an integrative modelling study. British Journal of Cancer. 106: 1280-7. PMID 22382688 DOI: 10.1038/bjc.2012.58  1
2012 Tafreshi NK, Bui MM, Bishop K, Lloyd MC, Enkemann SA, Lopez AS, Abrahams D, Carter BW, Vagner J, Grobmyer SR, Gobmyer SR, Gillies RJ, Morse DL. Noninvasive detection of breast cancer lymph node metastasis using carbonic anhydrases IX and XII targeted imaging probes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 207-19. PMID 22016510 DOI: 10.1158/1078-0432.CCR-11-0238  1
2012 Gillies RJ, Gelovani J. The World Molecular Imaging Society (WMIS) Molecular Imaging and Biology. 14: 1-3. DOI: 10.1007/s11307-011-0536-9  1
2011 Ibrahim-Hashim A, Wojtkowiak JW, de Lourdes Coelho Ribeiro M, Estrella V, Bailey KM, Cornnell HH, Gatenby RA, Gillies RJ. Free Base Lysine Increases Survival and Reduces Metastasis in Prostate Cancer Model. Journal of Cancer Science & Therapy. PMID 24032073  1
2011 Barkey NM, Tafreshi NK, Josan JS, De Silva CR, Sill KN, Hruby VJ, Gillies RJ, Morse DL, Vagner J. Development of melanoma-targeted polymer micelles by conjugation of a melanocortin 1 receptor (MC1R) specific ligand. Journal of Medicinal Chemistry. 54: 8078-84. PMID 22011200 DOI: 10.1021/jm201226w  1
2011 Wojtkowiak JW, Verduzco D, Schramm KJ, Gillies RJ. Drug resistance and cellular adaptation to tumor acidic pH microenvironment. Molecular Pharmaceutics. 8: 2032-8. PMID 21981633 DOI: 10.1021/mp200292c  1
2011 Rao V, Alleti R, Xu L, Tafreshi NK, Morse DL, Gillies RJ, Mash EA. A sucrose-derived scaffold for multimerization of bioactive peptides. Bioorganic & Medicinal Chemistry. 19: 6474-82. PMID 21940174 DOI: 10.1016/j.bmc.2011.08.053  1
2011 Brabez N, Lynch RM, Xu L, Gillies RJ, Chassaing G, Lavielle S, Hruby VJ. Design, synthesis, and biological studies of efficient multivalent melanotropin ligands: tools toward melanoma diagnosis and treatment. Journal of Medicinal Chemistry. 54: 7375-84. PMID 21928837 DOI: 10.1021/jm2009937  1
2011 Ibrahim Hashim A, Cornnell HH, Coelho Ribeiro Mde L, Abrahams D, Cunningham J, Lloyd M, Martinez GV, Gatenby RA, Gillies RJ. Reduction of metastasis using a non-volatile buffer. Clinical & Experimental Metastasis. 28: 841-9. PMID 21861189 DOI: 10.1007/s10585-011-9415-7  1
2011 Gatenby RA, Gillies RJ. Integrated imaging of cancer metabolism. Academic Radiology. 18: 929-31. PMID 21718952 DOI: 10.1016/j.acra.2011.05.005  1
2011 Huynh AS, Abrahams DF, Torres MS, Baldwin MK, Gillies RJ, Morse DL. Development of an orthotopic human pancreatic cancer xenograft model using ultrasound guided injection of cells. Plos One. 6: e20330. PMID 21647423 DOI: 10.1371/journal.pone.0020330  1
2011 Josan JS, Handl HL, Sankaranarayanan R, Xu L, Lynch RM, Vagner J, Mash EA, Hruby VJ, Gillies RJ. Cell-specific targeting by heterobivalent ligands. Bioconjugate Chemistry. 22: 1270-8. PMID 21639139 DOI: 10.1021/bc1004284  1
2011 Martinez GV, Zhang X, García-Martín ML, Morse DL, Woods M, Sherry AD, Gillies RJ. Imaging the extracellular pH of tumors by MRI after injection of a single cocktail of T1 and T2 contrast agents. Nmr in Biomedicine. 24: 1380-91. PMID 21604311 DOI: 10.1002/nbm.1701  1
2011 Gatenby RA, Gillies RJ, Brown JS. Of cancer and cave fish. Nature Reviews. Cancer. 11: 237-8. PMID 21548400 DOI: 10.1038/nrc3036  1
2011 Perfahl H, Byrne HM, Chen T, Estrella V, Alarcón T, Lapin A, Gatenby RA, Gillies RJ, Lloyd MC, Maini PK, Reuss M, Owen MR. Multiscale modelling of vascular tumour growth in 3D: the roles of domain size and boundary conditions. Plos One. 6: e14790. PMID 21533234 DOI: 10.1371/journal.pone.0014790  1
2011 Hashim AI, Zhang X, Wojtkowiak JW, Martinez GV, Gillies RJ. Imaging pH and metastasis. Nmr in Biomedicine. 24: 582-91. PMID 21387439 DOI: 10.1002/nbm.1644  1
2011 Tafreshi NK, Enkemann SA, Bui MM, Lloyd MC, Abrahams D, Huynh AS, Kim J, Grobmyer SR, Carter WB, Vagner J, Gillies RJ, Morse DL. A mammaglobin-A targeting agent for noninvasive detection of breast cancer metastasis in lymph nodes. Cancer Research. 71: 1050-9. PMID 21169406 DOI: 10.1158/0008-5472.CAN-10-3091  1
2011 Martin NK, Gaffney EA, Gatenby RA, Gillies RJ, Robey IF, Maini PK. A mathematical model of tumour and blood pHe regulation: The HCO3-/CO2 buffering system. Mathematical Biosciences. 230: 1-11. PMID 21167185 DOI: 10.1016/j.mbs.2010.12.002  1
2011 Basu S, Hall LO, Goldgof DB, Gu Y, Kumar V, Choi J, Gillies RJ, Gatenby RA. Developing a classifier model for lung tumors in CT-scan images Conference Proceedings - Ieee International Conference On Systems, Man and Cybernetics. 1306-1312. DOI: 10.1109/ICSMC.2011.6083840  1
2010 Gatenby RA, Gillies RJ, Brown JS. Evolutionary dynamics of cancer prevention. Nature Reviews. Cancer. 10: 526-7. PMID 21137109 DOI: 10.1038/nrc2892  1
2010 Alleti R, Rao V, Xu L, Gillies RJ, Mash EA. A solanesol-derived scaffold for multimerization of bioactive peptides. The Journal of Organic Chemistry. 75: 5895-903. PMID 20701315 DOI: 10.1021/jo101043m  1
2010 Zhang X, Lin Y, Gillies RJ. Tumor pH and its measurement. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 1167-70. PMID 20660380 DOI: 10.2967/jnumed.109.068981  1
2010 Lee YS, Fernandes S, Kulkarani V, Mayorov A, Davis P, Ma SW, Brown K, Gillies RJ, Lai J, Porreca F, Hruby VJ. Design and synthesis of trivalent ligands targeting opioid, cholecystokinin, and melanocortin receptors for the treatment of pain. Bioorganic & Medicinal Chemistry Letters. 20: 4080-4. PMID 20547453 DOI: 10.1016/j.bmcl.2010.05.078  1
2010 Gillies RJ, Anderson AR, Gatenby RA, Morse DL. The biology underlying molecular imaging in oncology: from genome to anatome and back again. Clinical Radiology. 65: 517-21. PMID 20541651 DOI: 10.1016/j.crad.2010.04.005  1
2010 Morse DL, Balagurunathan Y, Hostetter G, Trissal M, Tafreshi NK, Burke N, Lloyd M, Enkemann S, Coppola D, Hruby VJ, Gillies RJ, Han H. Identification of novel pancreatic adenocarcinoma cell-surface targets by gene expression profiling and tissue microarray. Biochemical Pharmacology. 80: 748-54. PMID 20510208 DOI: 10.1016/j.bcp.2010.05.018  1
2010 Morse DL, Gillies RJ. Molecular imaging and targeted therapies. Biochemical Pharmacology. 80: 731-8. PMID 20399197 DOI: 10.1016/j.bcp.2010.04.011  1
2010 Xu L, Vagner J, Alleti R, Rao V, Jagadish B, Morse DL, Hruby VJ, Gillies RJ, Mash EA. Synthesis and characterization of a Eu-DTPA-PEGO-MSH(4) derivative for evaluation of binding of multivalent molecules to melanocortin receptors. Bioorganic & Medicinal Chemistry Letters. 20: 2489-92. PMID 20304640 DOI: 10.1016/j.bmcl.2010.03.007  1
2010 Morse DL, Hostetter G, Balagurunathan Y, Gillies RJ, Han H. Identification of pancreatic cancer-specific cell-surface markers for development of targeting ligands. Methods in Molecular Biology (Clifton, N.J.). 624: 195-210. PMID 20217597 DOI: 10.1007/978-1-60761-609-2_13  1
2010 Silva AS, Gatenby RA, Gillies RJ, Yunes JA. A quantitative theoretical model for the development of malignancy in ductal carcinoma in situ. Journal of Theoretical Biology. 262: 601-13. PMID 19887072 DOI: 10.1016/j.jtbi.2009.10.031  1
2010 De Silva CR, Vagner J, Lynch R, Gillies RJ, Hruby VJ. Optimization of time-resolved fluorescence assay for detection of europium-tetraazacyclododecyltetraacetic acid-labeled ligand-receptor interactions. Analytical Biochemistry. 398: 15-23. PMID 19852924 DOI: 10.1016/j.ab.2009.10.031  1
2009 Xu L, Vagner J, Josan J, Lynch RM, Morse DL, Baggett B, Han H, Mash EA, Hruby VJ, Gillies RJ. Enhanced targeting with heterobivalent ligands. Molecular Cancer Therapeutics. 8: 2356-65. PMID 19671749 DOI: 10.1158/1535-7163.MCT-08-1183  1
2009 Lee HK, Smith MD, Smith BJ, Grussendorf J, Xu L, Gillies RJ, White HS, Bulaj G. Anticonvulsant Met-enkephalin analogues containing backbone spacers reveal alternative non-opioid signaling in the brain. Acs Chemical Biology. 4: 659-71. PMID 19634861 DOI: 10.1021/cb900045c  1
2009 Rosca EV, Gillies RJ, Caplan MR. Glioblastoma targeting via integrins is concentration dependent. Biotechnology and Bioengineering. 104: 408-17. PMID 19575417 DOI: 10.1002/bit.22424  1
2009 Gatenby RA, Silva AS, Gillies RJ, Frieden BR. Adaptive therapy. Cancer Research. 69: 4894-903. PMID 19487300 DOI: 10.1158/0008-5472.CAN-08-3658  1
2009 Josan JS, Morse DL, Xu L, Trissal M, Baggett B, Davis P, Vagner J, Gillies RJ, Hruby VJ. Solid-phase synthetic strategy and bioevaluation of a labeled delta-opioid receptor ligand Dmt-Tic-Lys for in vivo imaging. Organic Letters. 11: 2479-82. PMID 19445485 DOI: 10.1021/ol900200k  1
2009 Josan JS, Sankaranarayanan R, Handl HL, Fernandes S, Xu L, Vagner J, Gillies RJ, Hruby VJ. Heterobivalent ligands crosslink multiple cell-surface receptors--a step towards personal medicine. Advances in Experimental Medicine and Biology. 611: 413-4. PMID 19400245 DOI: 10.1007/978-0-387-73657-0_178  1
2009 Robey IF, Baggett BK, Kirkpatrick ND, Roe DJ, Dosescu J, Sloane BF, Hashim AI, Morse DL, Raghunand N, Gatenby RA, Gillies RJ. Bicarbonate increases tumor pH and inhibits spontaneous metastases. Cancer Research. 69: 2260-8. PMID 19276390 DOI: 10.1158/0008-5472.CAN-07-5575  1
2009 Silva AS, Yunes JA, Gillies RJ, Gatenby RA. The potential role of systemic buffers in reducing intratumoral extracellular pH and acid-mediated invasion. Cancer Research. 69: 2677-84. PMID 19276380 DOI: 10.1158/0008-5472.CAN-08-2394  1
2009 De Leon-Rodriguez LM, Lubag AJ, Malloy CR, Martinez GV, Gillies RJ, Sherry AD. Responsive MRI agents for sensing metabolism in vivo. Accounts of Chemical Research. 42: 948-57. PMID 19265438 DOI: 10.1021/ar800237f  1
2009 Morse DL, Carroll D, Day S, Gray H, Sadarangani P, Murthi S, Job C, Baggett B, Raghunand N, Gillies RJ. Characterization of breast cancers and therapy response by MRS and quantitative gene expression profiling in the choline pathway. Nmr in Biomedicine. 22: 114-27. PMID 19016452 DOI: 10.1002/nbm.1318  1
2008 Josan JS, Vagner J, Handl HL, Sankaranarayanan R, Gillies RJ, Hruby VJ. Solid-Phase Synthesis of Heterobivalent Ligands Targeted to Melanocortin and Cholecystokinin Receptors. International Journal of Peptide Research and Therapeutics. 14: 293-300. PMID 19714261 DOI: 10.1007/s10989-008-9150-3  1
2008 Shewmake TA, Solis FJ, Gillies RJ, Caplan MR. Effects of linker length and flexibility on multivalent targeting. Biomacromolecules. 9: 3057-64. PMID 18828631 DOI: 10.1021/bm800529b  1
2008 Balagurunathan Y, Morse DL, Hostetter G, Shanmugam V, Stafford P, Shack S, Pearson J, Trissal M, Demeure MJ, Von Hoff DD, Hruby VJ, Gillies RJ, Han H. Gene expression profiling-based identification of cell-surface targets for developing multimeric ligands in pancreatic cancer. Molecular Cancer Therapeutics. 7: 3071-80. PMID 18765825 DOI: 10.1158/1535-7163.MCT-08-0402  1
2008 Robey IF, Stephen RM, Brown KS, Baggett BK, Gatenby RA, Gillies RJ. Regulation of the Warburg effect in early-passage breast cancer cells. Neoplasia (New York, N.Y.). 10: 745-56. PMID 18670636 DOI: 10.1593/neo.07724  1
2008 Trouard TP, Harkins KD, Divijak JL, Gillies RJ, Galons JP. Ischemia-induced changes of intracellular water diffusion in rat glioma cell cultures. Magnetic Resonance in Medicine. 60: 258-64. PMID 18666112 DOI: 10.1002/mrm.21616  1
2008 Gillies RJ, Robey I, Gatenby RA. Causes and consequences of increased glucose metabolism of cancers Journal of Nuclear Medicine. 49: 24S-42S. PMID 18523064 DOI: 10.2967/jnumed.107.047258  1
2008 Jennings D, Raghunand N, Gillies RJ. Imaging hemodynamics Cancer and Metastasis Reviews. 27: 589-613. PMID 18506397 DOI: 10.1007/s10555-008-9157-4  1
2008 Lope-Piedrafita S, Garcia-Martin ML, Galons JP, Gillies RJ, Trouard TP. Longitudinal diffusion tensor imaging in a rat brain glioma model. Nmr in Biomedicine. 21: 799-808. PMID 18470959 DOI: 10.1002/nbm.1256  1
2008 Black KC, Kirkpatrick ND, Troutman TS, Xu L, Vagner J, Gillies RJ, Barton JK, Utzinger U, Romanowski M. Gold nanorods targeted to delta opioid receptor: plasmon-resonant contrast and photothermal agents. Molecular Imaging. 7: 50-7. PMID 18384724 DOI: 10.2310/7290.2008.0007  1
2008 Moellering RE, Black KC, Krishnamurty C, Baggett BK, Stafford P, Rain M, Gatenby RA, Gillies RJ. Acid treatment of melanoma cells selects for invasive phenotypes. Clinical & Experimental Metastasis. 25: 411-25. PMID 18301995 DOI: 10.1007/s10585-008-9145-7  1
2008 Vagner J, Xu L, Handl HL, Josan JS, Morse DL, Mash EA, Gillies RJ, Hruby VJ. Heterobivalent ligands crosslink multiple cell-surface receptors: the human melanocortin-4 and delta-opioid receptors. Angewandte Chemie (International Ed. in English). 47: 1685-8. PMID 18205159 DOI: 10.1002/anie.200702770  1
2008 Gatenby RA, Gillies RJ. A microenvironmental model of carcinogenesis Nature Reviews Cancer. 8: 56-61. PMID 18059462 DOI: 10.1038/nrc2255  1
2008 Borden MA, Zhang H, Gillies RJ, Dayton PA, Ferrara KW. A stimulus-responsive contrast agent for ultrasound molecular imaging Biomaterials. 29: 597-606. PMID 17977595 DOI: 10.1016/j.biomaterials.2007.10.011  1
2008 Philip RC, Rodriguez JJ, Gillies RJ. Seed pruning using a multi-resolution approach for automated segmentation of breast cancer tissue Proceedings - International Conference On Image Processing, Icip. 1436-1439. DOI: 10.1109/ICIP.2008.4712035  1
2008 Jordan BF, Galons JP, Gillies RJ. Post-treatment changes in tumor microenvironment: Dynamic contrast-enhanced and diffusion-weighted magnetic resonance imaging Cancer Imaging. 235-248. DOI: 10.1016/B978-012374212-4.50094-8  1
2007 Ackerstaff E, Artemov D, Gillies RJ, Bhujwalla ZM. Hypoxia and the presence of human vascular endothelial cells affect prostate cancer cell invasion and metabolism Neoplasia. 9: 1138-1151. PMID 18084621 DOI: 10.1593/neo.07568  1
2007 Rosca EV, Stukel JM, Gillies RJ, Vagner J, Caplan MR. Specificity and mobility of biomacromolecular, multivalent constructs for cellular targeting Biomacromolecules. 8: 3830-3835. PMID 18039007 DOI: 10.1021/bm700791a  1
2007 Gatenby RA, Smallbone K, Maini PK, Rose F, Averill J, Nagle RB, Worrall L, Gillies RJ. Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer. British Journal of Cancer. 97: 646-53. PMID 17687336 DOI: 10.1038/sj.bjc.6603922  1
2007 Borden MA, Caskey CF, Little E, Gillies RJ, Ferrara KW. DNA and polylysine adsorption and multilayer construction onto cationic lipid-coated microbubbles Langmuir. 23: 9401-9408. PMID 17665937 DOI: 10.1021/la7009034  1
2007 Morse DL, Raghunand N, Sadarangani P, Murthi S, Job C, Day S, Howison C, Gillies RJ. Response of choline metabolites to docetaxel therapy is quantified in vivo by localized (31)P MRS of human breast cancer xenografts and in vitro by high-resolution (31)P NMR spectroscopy of cell extracts. Magnetic Resonance in Medicine. 58: 270-80. PMID 17654590 DOI: 10.1002/mrm.21333  1
2007 Gillies RJ, Gatenby RA. Adaptive landscapes and emergent phenotypes: Why do cancers have high glycolysis? Journal of Bioenergetics and Biomembranes. 39: 251-257. PMID 17624581 DOI: 10.1007/s10863-007-9085-y  1
2007 Handl HL, Sankaranarayanan R, Josan JS, Vagner J, Mash EA, Gillies RJ, Hruby VJ. Synthesis and evaluation of bivalent NDP-alpha-MSH(7) peptide ligands for binding to the human melanocortin receptor 4 (hMC4R). Bioconjugate Chemistry. 18: 1101-9. PMID 17591746 DOI: 10.1021/bc0603642  1
2007 Gatenby RA, Gillies RJ. Glycolysis in cancer: A potential target for therapy International Journal of Biochemistry and Cell Biology. 39: 1358-1366. PMID 17499003 DOI: 10.1016/j.biocel.2007.03.021  1
2007 Jagadish B, Sankaranarayanan R, Xu L, Richards R, Vagner J, Hruby VJ, Gillies RJ, Mash EA. Squalene-derived flexible linkers for bioactive peptides. Bioorganic & Medicinal Chemistry Letters. 17: 3310-3. PMID 17448660 DOI: 10.1016/j.bmcl.2007.04.001  1
2007 Gillies RJ, Gatenby RA. Hypoxia and adaptive landscapes in the evolution of carcinogenesis Cancer and Metastasis Reviews. 26: 311-317. PMID 17404691 DOI: 10.1007/s10555-007-9065-z  1
2007 Stephen RM, Gillies RJ. Promise and progress for functional and molecular imaging of response to targeted therapies Pharmaceutical Research. 24: 1172-1185. PMID 17385018 DOI: 10.1007/s11095-007-9250-3  1
2007 Bowen ME, Monguchi Y, Sankaranarayanan R, Vagner J, Begay LJ, Xu L, Jagadish B, Hruby VJ, Gillies RJ, Mash EA. Design, synthesis, and validation of a branched flexible linker for bioactive peptides. The Journal of Organic Chemistry. 72: 1675-80. PMID 17279799 DOI: 10.1021/jo062276g  1
2007 Morse DL, Galons JP, Payne CM, Jennings DL, Day S, Xia G, Gillies RJ. MRI-measured water mobility increases in response to chemotherapy via multiple cell-death mechanisms. Nmr in Biomedicine. 20: 602-14. PMID 17265424 DOI: 10.1002/nbm.1127  1
2007 Smallbone K, Gatenby RA, Gillies RJ, Maini PK, Gavaghan DJ. Metabolic changes during carcinogenesis: potential impact on invasiveness. Journal of Theoretical Biology. 244: 703-13. PMID 17055536 DOI: 10.1016/j.jtbi.2006.09.010  1
2006 Sloane BF, Gillies RJ, Mohla S, Sogn JA, Menkens AE, Sullivan DC. I2 imaging: cancer biology and the tumor microenvironment. Cancer Research. 66: 11097-9. PMID 17114235 DOI: 10.1158/0008-5472.CAN-06-3102  1
2006 Vagner J, Handl HL, Monguchi Y, Jana U, Begay LJ, Mash EA, Hruby VJ, Gillies RJ. Rigid linkers for bioactive peptides. Bioconjugate Chemistry. 17: 1545-50. PMID 17105235 DOI: 10.1021/bc060154p  1
2006 Gatenby RA, Gawlinski ET, Gmitro AF, Kaylor B, Gillies RJ. Acid-mediated tumor invasion: a multidisciplinary study. Cancer Research. 66: 5216-23. PMID 16707446 DOI: 10.1158/0008-5472.CAN-05-4193  1
2006 Raghunand N, Jagadish B, Trouard TP, Galons JP, Gillies RJ, Mash EA. Redox-sensitive contrast agents for MRI based on reversible binding of thiols to serum albumin. Magnetic Resonance in Medicine. 55: 1272-80. PMID 16700014 DOI: 10.1002/mrm.20904  1
2006 Borden MA, Martinez GV, Ricker J, Tsvetkova N, Longo M, Gillies RJ, Dayton PA, Ferrara KW. Lateral phase separation in lipid-coated microbubbles. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 4291-7. PMID 16618177 DOI: 10.1021/la052841v  1
2006 Garcia-Martin ML, Martinez GV, Raghunand N, Sherry AD, Zhang S, Gillies RJ. High resolution pH(e) imaging of rat glioma using pH-dependent relaxivity. Magnetic Resonance in Medicine. 55: 309-15. PMID 16402385 DOI: 10.1002/mrm.20773  1
2006 Rajguru NS, Rodríguez JJ, Raghunand N, Gillies RJ. Enhanced level-set approach to segmentation of 3-D heterogeneous lesions from dynamic contrast-enhanced MR images Proceedings of the Ieee Southwest Symposium On Image Analysis and Interpretation. 2006: 71-75.  1
2005 Martinez-Zaguilan R, Tompkins LS, Gillies RJ, Lynch RM. Simultaneous analysis of intracellular pH and Ca²+ from cell populations. Methods in Molecular Biology (Clifton, N.J.). 312: 269-87. PMID 21341106 DOI: 10.1385/1-59259-949-4:269  1
2005 Morse DL, Gray H, Payne CM, Gillies RJ. Docetaxel induces cell death through mitotic catastrophe in human breast cancer cells. Molecular Cancer Therapeutics. 4: 1495-504. PMID 16227398 DOI: 10.1158/1535-7163.MCT-05-0130  1
2005 Jordan BF, Black K, Robey IF, Runquist M, Powis G, Gillies RJ. Metabolite changes in HT-29 xenograft tumors following HIF-1alpha inhibition with PX-478 as studied by MR spectroscopy in vivo and ex vivo. Nmr in Biomedicine. 18: 430-9. PMID 16206237 DOI: 10.1002/nbm.977  1
2005 Gillies RJ, Hoffman JM, Lam KS, Menkens AE, Piwnica-Worms DR, Sullivan DC, Weissleder R. Meeting report: high-throughput technologies for in vivo imaging agents. Molecular Imaging. 4: 98-103. PMID 16105507  1
2005 Handl HL, Vagner J, Yamamura HI, Hruby VJ, Gillies RJ. Development of a lanthanide-based assay for detection of receptor-ligand interactions at the delta-opioid receptor. Analytical Biochemistry. 343: 299-307. PMID 16004955 DOI: 10.1016/j.ab.2005.05.040  1
2005 Gillies RJ, Morse DL. In vivo magnetic resonance spectroscopy in cancer Annual Review of Biomedical Engineering. 7: 287-326. PMID 16004573 DOI: 10.1146/annurev.bioeng.7.060804.100411  1
2005 Galons JP, Lope-Piedrafita S, Divijak JL, Corum C, Gillies RJ, Trouard TP. Uncovering of intracellular water in cultured cells. Magnetic Resonance in Medicine. 54: 79-86. PMID 15968680 DOI: 10.1002/mrm.20565  1
2005 Robey IF, Lien AD, Welsh SJ, Baggett BK, Gillies RJ. Hypoxia-inducible factor-1alpha and the glycolytic phenotype in tumors. Neoplasia (New York, N.Y.). 7: 324-30. PMID 15967109 DOI: 10.1593/neo.04430  1
2005 Jordan BF, Runquist M, Raghunand N, Baker A, Williams R, Kirkpatrick L, Powis G, Gillies RJ. Dynamic contrast-enhanced and diffusion MRI show rapid and dramatic changes in tumor microenvironment in response to inhibition of HIF-1alpha using PX-478. Neoplasia (New York, N.Y.). 7: 475-85. PMID 15967100 DOI: 10.1593/neo.04628  1
2005 Morse DL, Carroll D, Weberg L, Borgstrom MC, Ranger-Moore J, Gillies RJ. Determining suitable internal standards for mRNA quantification of increasing cancer progression in human breast cells by real-time reverse transcriptase polymerase chain reaction. Analytical Biochemistry. 342: 69-77. PMID 15958182 DOI: 10.1016/j.ab.2005.03.034  1
2005 Handl HL, Gillies RJ. Lanthanide-based luminescent assays for ligand-receptor interactions Life Sciences. 77: 361-371. PMID 15894006 DOI: 10.1016/j.lfs.2005.01.009  1
2005 Jordan BF, Runquist M, Raghunand N, Gillies RJ, Tate WR, Powis G, Baker AF. The thioredoxin-1 inhibitor 1-methylpropyl 2-imidazolyl disulfide (PX-12) decreases vascular permeability in tumor xenografts monitored by dynamic contrast enhanced magnetic resonance imaging. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 529-36. PMID 15701837  1
2005 Gatenby RA, Vincent TL, Gillies RJ. Evolutionary dynamics in carcinogenesis Mathematical Models and Methods in Applied Sciences. 15: 1619-1638. DOI: 10.1142/S0218202505000911  1
2005 Monguchi Y, Vagner J, Handl HL, Jana U, Begay LJ, Hruby VJ, Gillies RJ, Mash EA. Design, synthesis, and validation of rigid linkers for bioactive peptides Tetrahedron Letters. 46: 7589-7592. DOI: 10.1016/j.tetlet.2005.08.151  1
2004 Baggett B, Roy R, Momen S, Morgan S, Tisi L, Morse D, Gillies RJ. Thermostability of firefly luciferases affects efficiency of detection by in vivo bioluminescence Molecular Imaging. 3: 324-332. PMID 15802049 DOI: 10.1162/1535350042973553  1
2004 Theilmann RJ, Borders R, Trouard TP, Xia G, Outwater E, Ranger-Moore J, Gillies RJ, Stopeck A. Changes in water mobility measured by diffusion MRI predict response of metastatic breast cancer to chemotherapy. Neoplasia (New York, N.Y.). 6: 831-7. PMID 15720810 DOI: 10.1593/neo.03343  1
2004 Gillies RJ, Raghunand N, Garcia-Martin ML, Gatenby RA. pH imaging Ieee Engineering in Medicine and Biology Magazine. 23: 57-64. PMID 15565800 DOI: 10.1109/MEMB.2004.1360409  1
2004 Bascuñan-Castillo EC, Erickson RP, Howison CM, Hunter RJ, Heidenreich RH, Hicks C, Trouard TP, Gillies RJ. Tamoxifen and vitamin E treatments delay symptoms in the mouse model of Niemann-Pick C. Journal of Applied Genetics. 45: 461-7. PMID 15523158  1
2004 Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nature Reviews Cancer. 4: 891-899. PMID 15516961 DOI: 10.1038/nrc1478  1
2004 Handl HL, Vagner J, Yamamura HI, Hruby VJ, Gillies RJ. Lanthanide-based time-resolved fluorescence of in cyto ligand-receptor interactions. Analytical Biochemistry. 330: 242-50. PMID 15203329 DOI: 10.1016/j.ab.2004.04.012  1
2004 Vagner J, Handl HL, Gillies RJ, Hruby VJ. Novel targeting strategy based on multimeric ligands for drug delivery and molecular imaging: homooligomers of alpha-MSH. Bioorganic & Medicinal Chemistry Letters. 14: 211-5. PMID 14684330 DOI: 10.1016/j.bmcl.2003.09.079  1
2004 Krishnamurthy C, Rodríguez JJ, Gillies RJ. Snake-Based Liver Lesion Segmentation Proceedings of the Ieee Southwest Symposium On Image Analysis and Interpretation. 6: 187-191.  1
2004 López-Larrubia P, García-Amo M, Mayoral EP, Gillies RJ, Cerdán S, Ballesteros P. τ-regioselective addition of (-)-Nα -tert-butoxycarbonyl-L-histidine methyl ester to diethyl fumarate Arkivoc. 2004: 26-31.  1
2003 Raghunand N, Gatenby RA, Gillies RJ. Microenvironmental and cellular consequences of altered blood flow in tumours. The British Journal of Radiology. 76: S11-22. PMID 15456710 DOI: 10.1259/bjr/12913493  1
2003 Lukasik VM, Gillies RJ. Animal anaesthesia for in vivo magnetic resonance Nmr in Biomedicine. 16: 459-467. PMID 14696002 DOI: 10.1002/nbm.836  1
2003 Raghunand N, Mahoney BP, Gillies RJ. Tumor acidity, ion trapping and chemotherapeutics. II. pH-dependent partition coefficients predict importance of ion trapping on pharmacokinetics of weakly basic chemotherapeutic agents. Biochemical Pharmacology. 66: 1219-29. PMID 14505801 DOI: 10.1016/S0006-2952(03)00468-4  1
2003 Mahoney BP, Raghunand N, Baggett B, Gillies RJ. Tumor acidity, ion trapping and chemotherapeutics. I. Acid pH affects the distribution of chemotherapeutic agents in vitro. Biochemical Pharmacology. 66: 1207-18. PMID 14505800 DOI: 10.1016/S0006-2952(03)00467-2  1
2003 Gillies RJ, Hruby VJ. Expression-driven reverse engineering of targeted imaging and therapeutic agents. Expert Opinion On Therapeutic Targets. 7: 137-9. PMID 12667092 DOI: 10.1517/14728222.7.2.137  1
2003 Schornack PA, Gillies RJ. Contributions of cell metabolism and H+ diffusion to the acidic pH of tumors. Neoplasia (New York, N.Y.). 5: 135-45. PMID 12659686  1
2003 Gillies RJ. Noninvasive imaging of anticancer therapy. Molecular Cancer Therapeutics. 2: 333-4. PMID 12657728  1
2003 Raghunand N, Howison C, Sherry AD, Zhang S, Gillies RJ. Renal and systemic pH imaging by contrast-enhanced MRI Magnetic Resonance in Medicine. 49: 249-257. PMID 12541244 DOI: 10.1002/mrm.10347  1
2003 Galons JP, Morse DL, Jennings DR, Gillies RJ. Diffusion-weighted MRI and response to anti-cancer therapies Israel Journal of Chemistry. 43: 91-101.  1
2003 Gillies RJ. Society for Molecular Imaging - Second Annual Meeting: 15-18 August 2003, San Francisco, CA, USA Idrugs. 6: 958-960.  1
2003 Gillies RJ. An image of faster drug development Current Drug Discovery. 35-37.  1
2002 Gillies RJ. In vivo molecular imaging. Journal of Cellular Biochemistry. Supplement. 39: 231-8. PMID 12552622 DOI: 10.1002/jcb.10450  1
2002 Gillies RJ, Raghunand N, Karczmar GS, Bhujwalla ZM. MRI of the tumor microenvironment. Journal of Magnetic Resonance Imaging : Jmri. 16: 430-50. PMID 12353258 DOI: 10.1002/jmri.10181  1
2002 Raghunand N, Zhang S, Sherry AD, Gillies RJ. In vivo magnetic resonance imaging of tissue pH using a novel pH-sensitive contrast agent, GdDOTA-4AmP Academic Radiology. 9: S481-S483. PMID 12188315 DOI: 10.1016/S1076-6332(03)80270-2  1
2002 Jennings D, Hatton BN, Guo J, Galons JP, Trouard TP, Raghunand N, Marshall J, Gillies RJ. Early response of prostate carcinoma xenografts to docetaxel chemotherapy monitored with diffusion MRI. Neoplasia (New York, N.Y.). 4: 255-62. PMID 11988845 DOI: 10.1038/sj/neo/7900225  1
2002 Bhujwalla ZM, Artemov D, Ballesteros P, Cerdan S, Gillies RJ, Solaiyappan M. Combined vascular and extracellular pH imaging of solid tumors Nmr in Biomedicine. 15: 114-119. PMID 11870907 DOI: 10.1002/nbm.743  1
2002 Veress AI, Weiss JA, Gillies RJ, Bowden AE, Galons JP, Rabbitt RD. Deformable image registration of mouse brain MRI data using hyperelastic warping Asme International Mechanical Engineering Congress and Exposition, Proceedings. 195-196. DOI: 10.1115/IMECE2002-32375  1
2001 Gillies RJ, Lynch RM. Frontiers in the measurement of cell and tissue pH. Novartis Foundation Symposium. 240: 7-19; discussion 19-. PMID 11727938  1
2001 Bhujwalla ZM, Artemov D, Aboagye E, Ackerstaff E, Gillies RJ, Natarajan K, Solaiyappan M. The physiological environment in cancer vascularization, invasion and metastasis Novartis Foundation Symposium. 240: 23-38. PMID 11727932  1
2001 Raghunand N, Gillies RJ. pH and chemotherapy Novartis Foundation Symposium. 240: 199-211. PMID 11727930  1
2001 Gillies RJ. The tumour microenvironment: causes and consequences of hypoxia and acidity. Introduction Novartis Foundation Symposium. 240: 1-6. PMID 11727923  1
2001 Raghunand N, Mahoney B, van Sluis R, Baggett B, Gillies RJ. Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone. Neoplasia (New York, N.Y.). 3: 227-35. PMID 11494116 DOI: 10.1038/sj/neo/7900151  1
2000 Gillies RJ. Causes and consequences of hypoxia and acidity in tumors - Novartis foundation symposium Trends in Molecular Medicine. 7: 47-49. PMID 11330256 DOI: 10.1016/S1471-4914(01)01913-X  1
2000 Gillies RJ, Bhujwalla ZM, Evelhoch J, Garwood M, Neeman M, Robinson SP, Sotak CH, Van Der Sanden B. Applications of magnetic resonance in model systems: tumor biology and physiology. Neoplasia (New York, N.Y.). 2: 139-51. PMID 10933073  1
1999 Raghunand N, Martínez-Zaguilán R, Wright SH, Gillies RJ. pH and drug resistance. II. Turnover of acidic vesicles and resistance to weakly basic chemotherapeutic drugs. Biochemical Pharmacology. 57: 1047-58. PMID 10796075  1
1999 Martínez-Zaguilán R, Raghunand N, Lynch RM, Bellamy W, Martinez GM, Rojas B, Smith D, Dalton WS, Gillies RJ. pH and drug resistance. I. Functional expression of plasmalemmal V-type H+-ATPase in drug-resistant human breast carcinoma cell lines. Biochemical Pharmacology. 57: 1037-46. PMID 10796074 DOI: 10.1016/S0006-2952(99)00022-2  1
1999 van Sluis R, Bhujwalla ZM, Raghunand N, Ballesteros P, Alvarez J, Cerdán S, Galons JP, Gillies RJ. In vivo imaging of extracellular pH using 1H MRSI. Magnetic Resonance in Medicine. 41: 743-50. PMID 10332850 DOI: 10.1002/(SICI)1522-2594(199904)41:4<743::AID-MRM13>3.0.CO;2-Z  1
1999 Raghunand N, Altbach MI, van Sluis R, Baggett B, Taylor CW, Bhujwalla ZM, Gillies RJ. Plasmalemmal pH-gradients in drug-sensitive and drug-resistant MCF-7 human breast carcinoma xenografts measured by 31P magnetic resonance spectroscopy. Biochemical Pharmacology. 57: 309-12. PMID 9890558 DOI: 10.1016/S0006-2952(98)00306-2  1
1996 Aiken NR, Gillies RJ. Phosphomonoester metabolism as a function of cell proliferative status and exogenous precursors. Anticancer Research. 16: 1393-7. PMID 8694507  0.24
1996 Martínez-Zaguilán R, Seftor EA, Seftor RE, Chu YW, Gillies RJ, Hendrix MJ. Acidic pH enhances the invasive behavior of human melanoma cells. Clinical & Experimental Metastasis. 14: 176-86. PMID 8605731  1
1994 Peterson EP, Martinez GM, Martinez-Zaguilan R, Perona R, Gillies RJ. NIH 3T3 cells transfected with a yeast H(+)-ATPase have altered sensitivity to insulin, insulin growth factor-I, and platelet-derived growth factor-AA. Journal of Cellular Physiology. 159: 551-60. PMID 8188769 DOI: 10.1002/jcp.1041590319  1
1994 Gillies RJ, Liu Z, Bhujwalla Z. 31P-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate. The American Journal of Physiology. 267: C195-203. PMID 8048479  0.01
1994 Gillies RJ, Barry JA, Ross BD. In vitro and in vivo 13C and 31P NMR analyses of phosphocholine metabolism in rat glioma cells. Magnetic Resonance in Medicine. 32: 310-8. PMID 7984063  1
1994 Martínez-Zaguilán R, Wegner JA, Gillies RJ, Hoyer PB. Differential regulation of Ca2+ homeostasis in ovine large and small luteal cells. Endocrinology. 135: 2099-108. PMID 7956933 DOI: 10.1210/endo.135.5.7956933  1
1994 Martínez-Zaguilán R, Gillies RJ, Sánchez-Armass S. Regulation of pH in rat brain synaptosomes. II. Role of Cl-. Journal of Neurophysiology. 71: 2249-57. PMID 7931514  1
1994 Martínez GM, Martínez-Zaguilán R, Gillies RJ. Effect of glucose on pHin and [Ca2+]in in NIH-3T3 cells transfected with the yeast P-type H(+)-ATPase. Journal of Cellular Physiology. 161: 129-41. PMID 7929598 DOI: 10.1002/jcp.1041610116  1
1993 Barry JA, McGovern KA, Lien YH, Ashmore B, Gillies RJ. Dimethyl methylphosphonate (DMMP): a 31P nuclear magnetic resonance spectroscopic probe of intracellular volume in mammalian cell cultures. Biochemistry. 32: 4665-70. PMID 8485143  1
1993 Gillies RJ, Galons JP, McGovern KA, Scherer PG, Lien YH, Job C, Ratcliff R, Chapa F, Cerdan S, Dale BE. Design and application of NMR-compatible bioreactor circuits for extended perfusion of high-density mammalian cell cultures. Nmr in Biomedicine. 6: 95-104. PMID 8457432  1
1993 Martinez-Zaguilan R, Lynch RM, Martinez GM, Gillies RJ. Vacuolar-type H(+)-ATPases are functionally expressed in plasma membranes of human tumor cells. The American Journal of Physiology. 265: C1015-29. PMID 8238296  1
1992 Gillies RJ. Nuclear magnetic resonance and its applications to physiological problems. Annual Review of Physiology. 54: 733-48. PMID 1562189 DOI: 10.1146/annurev.ph.54.030192.003505  0.01
1992 Lien YH, Zhou HZ, Job C, Barry JA, Gillies RJ. In vivo 31P NMR study of early cellular responses to hyperosmotic shock in cultured glioma cells. Biochimie. 74: 931-9. PMID 1467347  1
1992 Martínez-Zaguilán R, Gillies RJ. A plasma membrane V-type H(+)-ATPase may contribute to elevated intracellular pH (pHin) in some human tumor cells. Annals of the New York Academy of Sciences. 671: 478-80. PMID 1288345  1
1991 Gillies RJ, Scherer PG, Raghunand N, Okerlund LS, Martinez-Zaguilan R, Hesterberg L, Dale BE. Iteration of hybridoma growth and productivity in hollow fiber bioreactors using 31P NMR. Magnetic Resonance in Medicine. 18: 181-92. PMID 2062229  1
1991 Martínez-Zaguilán R, Martínez GM, Lattanzio F, Gillies RJ. Simultaneous measurement of intracellular pH and Ca2+ using the fluorescence of SNARF-1 and fura-2. The American Journal of Physiology. 260: C297-307. PMID 1996613  1
1991 Gillies RJ, Martinez-Zaguilan R. Regulation of intracellular pH in BALB/c 3T3 cells. Bicarbonate raises pH via NaHCO3/HCl exchange and attenuates the activation of Na+/H+ exchange by serum. The Journal of Biological Chemistry. 266: 1551-6. PMID 1846359  1
1990 Gillies RJ, Martinez-Zaguilan R, Martinez GM, Serrano R, Perona R. Tumorigenic 3T3 cells maintain an alkaline intracellular pH under physiological conditions. Proceedings of the National Academy of Sciences of the United States of America. 87: 7414-8. PMID 2170979  1
1983 Findly RC, Gillies RJ, Shulman RG. In vivo phosphorus-31 nuclear magnetic resonance reveals lowered ATP during heat shock of Tetrahymena. Science (New York, N.Y.). 219: 1223-5. PMID 6828852  1
1982 Gillies RJ, Ogino T, Shulman RG, Ward DC. 31P nuclear magnetic resonance evidence for the regulation of intracellular pH by Ehrlich ascites tumor cells. The Journal of Cell Biology. 95: 24-8. PMID 7142288  1
1981 Alger JR, Sillerud LO, Behar KL, Gillies RJ, Shulman RG, Gordon RE, Shae D, Hanley PE. In vivo carbon-13 nuclear magnetic resonance studies of mammals. Science (New York, N.Y.). 214: 660-2. PMID 7292005 DOI: 10.1126/science.7292005  1
1981 Gillies RJ, Alger JR, den Hollander JA, Shulman RG. Intracellular pH measured by NMR: methods and results. Kroc Foundation Series. 15: 79-104. PMID 7042927  1
1981 Gillies RJ, Ugurbil K, den Hollander JA, Shulman RG. 31P NMR studies of intracellular pH and phosphate metabolism during cell division cycle of Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 78: 2125-9. PMID 7017724  1
1981 Gillies RJ, Rosenberg MP, Deamer DW. Carbon dioxide efflux accompanies release of fertilization acid from sea urchin eggs. Journal of Cellular Physiology. 108: 115-22. PMID 6790553 DOI: 10.1002/jcp.1041080202  1
1980 Gillies RJ, Deamer DW. Endogenously produced CO2 induces stationary phase in Tetrahymena cultures. Journal of Cellular Physiology. 105: 221-5. PMID 6780574 DOI: 10.1002/jcp.1041050205  1
1979 Gillies RJ, Deamer DW. Intracellular pH changes during the cell cycle in Tetrahymena. Journal of Cellular Physiology. 100: 23-31. PMID 38259 DOI: 10.1002/jcp.1041000103  1
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