F. A. Romero, Ph.D. - Publications

Affiliations: 
University of Kansas, Lawrence, KS, United States 
Area:
neurotransmitters and drugs affecting them in the central nervous system

11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

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Year Citation  Score
2008 Kimball FS, Romero FA, Ezzili C, Garfunkle J, Rayl TJ, Hochstatter DG, Hwang I, Boger DL. Optimization of alpha-ketooxazole inhibitors of fatty acid amide hydrolase. Journal of Medicinal Chemistry. 51: 937-47. PMID 18247553 DOI: 10.1021/jm701210y  1
2007 Hardouin C, Kelso MJ, Romero FA, Rayl TJ, Leung D, Hwang I, Cravatt BF, Boger DL. Structure-activity relationships of alpha-ketooxazole inhibitors of fatty acid amide hydrolase. Journal of Medicinal Chemistry. 50: 3359-68. PMID 17559203 DOI: 10.1021/jm061414r  1
2007 Romero FA, Du W, Hwang I, Rayl TJ, Kimball FS, Leung D, Hoover HS, Apodaca RL, Breitenbucher JG, Cravatt BF, Boger DL. Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase. Journal of Medicinal Chemistry. 50: 1058-68. PMID 17279740 DOI: 10.1021/jm0611509  1
2006 Romero FA, Hwang I, Boger DL. Delineation of a fundamental alpha-ketoheterocycle substituent effect for use in the design of enzyme inhibitors. Journal of the American Chemical Society. 128: 14004-5. PMID 17061864 DOI: 10.1021/ja064522b  1
2006 Schnermann MJ, Romero FA, Hwang I, Nakamaru-Ogiso E, Yagi T, Boger DL. Total synthesis of piericidin A1 and B1 and key analogues. Journal of the American Chemical Society. 128: 11799-807. PMID 16953619 DOI: 10.1021/ja0632862  1
2005 Grunewald GL, Romero FA, Criscione KR. Nanomolar inhibitors of CNS epinephrine biosynthesis: (R)-(+)-3-fluoromethyl-7-(N-substituted aminosulfonyl)-1,2,3,4-tetrahydroisoquinolines as potent and highly selective inhibitors of phenylethanolamine N-methyltransferase1. Journal of Medicinal Chemistry. 48: 1806-12. PMID 15771426 DOI: 10.1021/jm049594x  1
2005 Grunewald GL, Romero FA, Seim MR, Criscione KR, Deupree JD, Spackman CC, Bylund DB. Exploring the active site of phenylethanolamine N-methyltransferase with 3-hydroxyethyl- and 3-hydroxypropyl-7-substituted-1,2,3,4-tetrahydroisoquinolines. Bioorganic & Medicinal Chemistry Letters. 15: 1143-7. PMID 15686930 DOI: 10.1016/j.bmcl.2004.12.013  1
2005 Grunewald GL, Romero FA, Chieu AD, Fincham KJ, Bhat SR, Criscione KR. Exploring the active site of phenylethanolamine N-methyltransferase: 3-alkyl-7-substituted-1,2,3,4-tetrahydroisoquinoline inhibitors. Bioorganic & Medicinal Chemistry. 13: 1261-73. PMID 15670935 DOI: 10.1016/j.bmc.2004.11.015  1
2005 Grunewald GL, Romero FA, Criscione KR. 3-hydroxymethyl-7-(N-substituted aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline inhibitors of phenylethanolamine N-methyltransferase that display remarkable potency and selectivity. Journal of Medicinal Chemistry. 48: 134-40. PMID 15634007 DOI: 10.1021/jm049368n  1
2004 Romero FA, Vodonick SM, Criscione KR, McLeish MJ, Grunewald GL. Inhibitors of phenylethanolamine N-methyltransferase that are predicted to penetrate the blood-brain barrier: design, synthesis, and evaluation of 3-fluoromethyl-7-(N-substituted aminosulfonyl)-1,2,3,4-tetrahydroisoquinolines that possess low affinity toward the alpha2-adrenoceptor. Journal of Medicinal Chemistry. 47: 4483-93. PMID 15317460 DOI: 10.1021/jm0400653  1
2002 Lankin DC, Grunewald GL, Romero FA, Oren IY, Snyder JP. The NH---FC dipole orientation effect for pendant exocyclic CH(2)F. Organic Letters. 4: 3557-60. PMID 12375886 DOI: 10.1021/ol026358c  1
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