| Year |
Citation |
Score |
| 2020 |
Alonso-Caballero A, Echelman DJ, Tapia-Rojo R, Haldar S, Eckels EC, Fernandez JM. Protein folding modulates the chemical reactivity of a Gram-positive adhesin. Nature Chemistry. PMID 33257887 DOI: 10.1038/s41557-020-00586-x |
1 |
|
| 2020 |
Tapia-Rojo R, Alonso-Caballero A, Fernandez JM. Direct observation of a coil-to-helix contraction triggered by vinculin binding to talin. Science Advances. 6: eaaz4707. PMID 32494739 DOI: 10.1126/sciadv.aaz4707 |
1 |
|
| 2018 |
Berkovich R, Fernandez VI, Stirnemann G, Valle-Orero J, Fernandez JM. Segmentation and the Entropic Elasticity of Modular Proteins. The Journal of Physical Chemistry Letters. PMID 30058807 DOI: 10.1021/acs.jpclett.8b01925 |
1 |
|
| 2018 |
Giganti D, Yan K, Badilla CL, Fernandez JM, Alegre-Cebollada J. Disulfide isomerization reactions in titin immunoglobulin domains enable a mode of protein elasticity. Nature Communications. 9: 185. PMID 29330363 DOI: 10.1038/s41467-017-02528-7 |
1 |
|
| 2017 |
Haldar S, Tapia-Rojo R, Eckels EC, Valle-Orero J, Fernandez JM. Trigger factor chaperone acts as a mechanical foldase. Nature Communications. 8: 668. PMID 28939815 DOI: 10.1038/s41467-017-00771-6 |
1 |
|
| 2017 |
Valle-Orero J, Tapia-Rojo R, Eckels EC, Rivas-Pardo JA, Popa I, Fernandez JM. Proteins Breaking Bad: A Free Energy Perspective. The Journal of Physical Chemistry Letters. PMID 28723106 DOI: 10.1021/acs.jpclett.7b01509 |
1 |
|
| 2017 |
Valle Orero J, Rivas-Pardo JA, Tapia-Rojo R, Popa I, Echelman DJ, Haldar S, Fernandez JM. Mechanical deformation accelerates protein ageing. Angewandte Chemie (International Ed. in English). PMID 28470663 DOI: 10.1002/anie.201703630 |
1 |
|
| 2016 |
Popa I, Rivas-Pardo JA, Eckels EC, Echelman D, Valle-Orero J, Fernandez JM. A HaloTag Anchored Ruler for Week-Long Studies of Protein Dynamics. Journal of the American Chemical Society. PMID 27409974 DOI: 10.1021/jacs.6b05429 |
1 |
|
| 2015 |
Rivas-Pardo JA, Alegre-Cebollada J, Ramírez-Sarmiento CA, Fernandez JM, Guixé V. Identifying sequential substrate binding at the single-molecule level by enzyme mechanical stabilization. Acs Nano. 9: 3996-4005. PMID 25840594 DOI: 10.1021/nn507480v |
1 |
|
| 2015 |
Valle-Orero J, Eckels EC, Stirnemann G, Popa I, Berkovich R, Fernandez JM. The elastic free energy of a tandem modular protein under force. Biochemical and Biophysical Research Communications. 460: 434-8. PMID 25796331 DOI: 10.1016/j.bbrc.2015.03.051 |
1 |
|
| 2015 |
Chen H, Yuan G, Winardhi RS, Yao M, Popa I, Fernandez JM, Yan J. Dynamics of equilibrium folding and unfolding transitions of titin immunoglobulin domain under constant forces. Journal of the American Chemical Society. 137: 3540-6. PMID 25726700 DOI: 10.1021/ja5119368 |
1 |
|
| 2014 |
Perez-Jimenez R, Alonso-Caballero A, Berkovich R, Franco D, Chen MW, Richard P, Badilla CL, Fernandez JM. Probing the effect of force on HIV-1 receptor CD4. Acs Nano. 8: 10313-20. PMID 25299596 DOI: 10.1021/nn503557w |
1 |
|
| 2014 |
Solsona C, Kahn TB, Badilla CL, Ãlvarez-Zaldiernas C, Blasi J, Fernandez JM, Alegre-Cebollada J. Altered thiol chemistry in human amyotrophic lateral sclerosis-linked mutants of superoxide dismutase 1. The Journal of Biological Chemistry. 289: 26722-32. PMID 25096579 DOI: 10.1074/jbc.M114.565333 |
1 |
|
| 2013 |
Ingles-Prieto A, Ibarra-Molero B, Delgado-Delgado A, Perez-Jimenez R, Fernandez JM, Gaucher EA, Sanchez-Ruiz JM, Gavira JA. Conservation of protein structure over four billion years Structure. 21: 1690-1697. PMID 23932589 DOI: 10.1016/j.str.2013.06.020 |
1 |
|
| 2013 |
Popa I, Berkovich R, Alegre-Cebollada J, Badilla CL, Rivas-Pardo JA, Taniguchi Y, Kawakami M, Fernandez JM. Nanomechanics of HaloTag tethers. Journal of the American Chemical Society. 135: 12762-71. PMID 23909704 DOI: 10.1021/ja4056382 |
1 |
|
| 2013 |
Kan Z, Zheng H, Liu X, Li S, Barber TD, Gong Z, Gao H, Hao K, Willard MD, Xu J, Hauptschein R, Rejto PA, Fernandez J, Wang G, Zhang Q, et al. Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma. Genome Research. 23: 1422-33. PMID 23788652 DOI: 10.1101/gr.154492.113 |
0.44 |
|
| 2013 |
Popa I, Kosuri P, Alegre-Cebollada J, Garcia-Manyes S, Fernandez JM. Force dependency of biochemical reactions measured by single-molecule force-clamp spectroscopy. Nature Protocols. 8: 1261-76. PMID 23744288 DOI: 10.1038/nprot.2013.056 |
1 |
|
| 2013 |
Stirnemann G, Giganti D, Fernandez JM, Berne BJ. Elasticity, structure, and relaxation of extended proteins under force. Proceedings of the National Academy of Sciences of the United States of America. 110: 3847-52. PMID 23407163 DOI: 10.1073/pnas.1300596110 |
1 |
|
| 2013 |
Javadi Y, Fernandez JM, Perez-Jimenez R. Protein folding under mechanical forces: a physiological view. Physiology (Bethesda, Md.). 28: 9-17. PMID 23280353 DOI: 10.1152/physiol.00017.2012 |
1 |
|
| 2012 |
Berkovich R, Hermans RI, Popa I, Stirnemann G, Garcia-Manyes S, Berne BJ, Fernandez JM. Rate limit of protein elastic response is tether dependent. Proceedings of the National Academy of Sciences of the United States of America. 109: 14416-21. PMID 22895787 DOI: 10.1073/pnas.1212167109 |
1 |
|
| 2011 |
Dougan L, Genchev GZ, Lu H, Fernandez JM. Probing osmolyte participation in the unfolding transition state of a protein. Proceedings of the National Academy of Sciences of the United States of America. 108: 9759-64. PMID 21613570 DOI: 10.1073/pnas.1101934108 |
1 |
|
| 2011 |
Perez-Jimenez R, Inglés-Prieto A, Zhao ZM, Sanchez-Romero I, Alegre-Cebollada J, Kosuri P, Garcia-Manyes S, Kappock TJ, Tanokura M, Holmgren A, Sanchez-Ruiz JM, Gaucher EA, Fernandez JM. Single-molecule paleoenzymology probes the chemistry of resurrected enzymes. Nature Structural & Molecular Biology. 18: 592-6. PMID 21460845 DOI: 10.1038/nsmb.2020 |
1 |
|
| 2010 |
Li J, Fernandez JM, Berne BJ. Water's role in the force-induced unfolding of ubiquitin. Proceedings of the National Academy of Sciences of the United States of America. 107: 19284-9. PMID 20974922 DOI: 10.1073/pnas.1013159107 |
1 |
|
| 2010 |
Berkovich R, Garcia-Manyes S, Urbakh M, Klafter J, Fernandez JM. Collapse dynamics of single proteins extended by force. Biophysical Journal. 98: 2692-701. PMID 20513414 DOI: 10.1016/j.bpj.2010.02.053 |
1 |
|
| 2010 |
Rodriguez-Larrea D, Perez-Jimenez R, Sanchez-Romero I, Delgado-Delgado A, Fernandez JM, Sanchez-Ruiz JM. Role of conservative mutations in protein multi-property adaptation. The Biochemical Journal. 429: 243-9. PMID 20446918 DOI: 10.1042/BJ20100386 |
1 |
|
| 2010 |
Alegre-Cebollada J, Perez-Jimenez R, Kosuri P, Fernandez JM. Single-molecule force spectroscopy approach to enzyme catalysis. The Journal of Biological Chemistry. 285: 18961-6. PMID 20382731 DOI: 10.1074/jbc.R109.011932 |
1 |
|
| 2009 |
Fernandez VI, Kosuri P, Parot V, Fernandez JM. Extended Kalman filter estimates the contour length of a protein in single molecule atomic force microscopy experiments. The Review of Scientific Instruments. 80: 113104. PMID 19947714 DOI: 10.1063/1.3252982 |
1 |
|
| 2009 |
Grützner A, Garcia-Manyes S, Kötter S, Badilla CL, Fernandez JM, Linke WA. Modulation of titin-based stiffness by disulfide bonding in the cardiac titin N2-B unique sequence. Biophysical Journal. 97: 825-34. PMID 19651040 DOI: 10.1016/j.bpj.2009.05.037 |
1 |
|
| 2009 |
Perez-Jimenez R, Li J, Kosuri P, Sanchez-Romero I, Wiita AP, Rodriguez-Larrea D, Chueca A, Holmgren A, Miranda-Vizuete A, Becker K, Cho SH, Beckwith J, Gelhaye E, Jacquot JP, Gaucher EA, ... ... Fernandez JM, et al. Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy. Nature Structural & Molecular Biology. 16: 890-6. PMID 19597482 DOI: 10.1038/nsmb.1627 |
1 |
|
| 2009 |
Dougan L, Li J, Badilla CL, Berne BJ, Fernandez JM. Single homopolypeptide chains collapse into mechanically rigid conformations. Proceedings of the National Academy of Sciences of the United States of America. 106: 12605-10. PMID 19549822 DOI: 10.1073/pnas.0900678106 |
1 |
|
| 2009 |
del Rio A, Perez-Jimenez R, Liu R, Roca-Cusachs P, Fernandez JM, Sheetz MP. Stretching single talin rod molecules activates vinculin binding. Science (New York, N.Y.). 323: 638-41. PMID 19179532 DOI: 10.1126/science.1162912 |
1 |
|
| 2008 |
Dougan L, Koti AS, Genchev G, Lu H, Fernandez JM. A single-molecule perspective on the role of solvent hydrogen bonds in protein folding and chemical reactions. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 9: 2836-47. PMID 19058277 DOI: 10.1002/cphc.200800572 |
1 |
|
| 2008 |
Perez-Jimenez R, Wiita AP, Rodriguez-Larrea D, Kosuri P, Gavira JA, Sanchez-Ruiz JM, Fernandez JM. Force-clamp spectroscopy detects residue co-evolution in enzyme catalysis. The Journal of Biological Chemistry. 283: 27121-9. PMID 18687682 DOI: 10.1074/jbc.M803746200 |
1 |
|
| 2008 |
Koti Ainavarapu SR, Wiita AP, Dougan L, Uggerud E, Fernandez JM. Single-molecule force spectroscopy measurements of bond elongation during a bimolecular reaction. Journal of the American Chemical Society. 130: 6479-87. PMID 18433129 DOI: 10.1021/ja800180u |
1 |
|
| 2008 |
Dougan L, Feng G, Lu H, Fernandez JM. Solvent molecules bridge the mechanical unfolding transition state of a protein. Proceedings of the National Academy of Sciences of the United States of America. 105: 3185-90. PMID 18305176 DOI: 10.1073/pnas.0706075105 |
1 |
|
| 2008 |
Ainavarapu SR, Wiita AP, Huang HH, Fernandez JM. A single-molecule assay to directly identify solvent-accessible disulfide bonds and probe their effect on protein folding. Journal of the American Chemical Society. 130: 436-7. PMID 18088123 DOI: 10.1021/ja077851s |
1 |
|
| 2008 |
Szoszkiewicz R, Ainavarapu SR, Wiita AP, Perez-Jimenez R, Sanchez-Ruiz JM, Fernandez JM. Dwell time analysis of a single-molecule mechanochemical reaction. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 1356-64. PMID 17999545 DOI: 10.1021/la702368b |
1 |
|
| 2007 |
Dougan L, Fernandez JM. Tandem repeating modular proteins avoid aggregation in single molecule force spectroscopy experiments. The Journal of Physical Chemistry. A. 111: 12402-8. PMID 18020430 DOI: 10.1021/jp076095+ |
1 |
|
| 2007 |
Wiita AP, Perez-Jimenez R, Walther KA, Gräter F, Berne BJ, Holmgren A, Sanchez-Ruiz JM, Fernandez JM. Probing the chemistry of thioredoxin catalysis with force. Nature. 450: 124-7. PMID 17972886 DOI: 10.1038/nature06231 |
1 |
|
| 2007 |
Walther KA, Gräter F, Dougan L, Badilla CL, Berne BJ, Fernandez JM. Signatures of hydrophobic collapse in extended proteins captured with force spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 104: 7916-21. PMID 17470816 DOI: 10.1073/pnas.0702179104 |
1 |
|
| 2007 |
Brujic J, Hermans RI, Garcia-Manyes S, Walther KA, Fernandez JM. Dwell-time distribution analysis of polyprotein unfolding using force-clamp spectroscopy. Biophysical Journal. 92: 2896-903. PMID 17259284 DOI: 10.1529/biophysj.106.099481 |
1 |
|
| 2007 |
Sarkar A, Caamano S, Fernandez JM. The mechanical fingerprint of a parallel polyprotein dimer. Biophysical Journal. 92: L36-8. PMID 17158577 DOI: 10.1529/biophysj.106.097741 |
1 |
|
| 2007 |
Ainavarapu SR, Brujic J, Huang HH, Wiita AP, Lu H, Li L, Walther KA, Carrion-Vazquez M, Li H, Fernandez JM. Contour length and refolding rate of a small protein controlled by engineered disulfide bonds. Biophysical Journal. 92: 225-33. PMID 17028145 DOI: 10.1529/biophysj.106.091561 |
1 |
|
| 2006 |
Perez-Jimenez R, Garcia-Manyes S, Ainavarapu SR, Fernandez JM. Mechanical unfolding pathways of the enhanced yellow fluorescent protein revealed by single molecule force spectroscopy. The Journal of Biological Chemistry. 281: 40010-4. PMID 17082195 DOI: 10.1074/jbc.M609890200 |
1 |
|
| 2006 |
Ainavarapu SR, Li L, Fernandez JM. Fingerprinting DHFR in single-molecule AFM studies. Biophysical Journal. 91: 2009-10, discussion . PMID 16782796 DOI: 10.1529/biophysj.106.085126 |
1 |
|
| 2006 |
Wiita AP, Ainavarapu SR, Huang HH, Fernandez JM. Force-dependent chemical kinetics of disulfide bond reduction observed with single-molecule techniques. Proceedings of the National Academy of Sciences of the United States of America. 103: 7222-7. PMID 16645035 DOI: 10.1073/pnas.0511035103 |
1 |
|
| 2006 |
Li L, Wetzel S, Plückthun A, Fernandez JM. Stepwise unfolding of ankyrin repeats in a single protein revealed by atomic force microscopy. Biophysical Journal. 90: L30-2. PMID 16387766 DOI: 10.1529/biophysj.105.078436 |
1 |
|
| 2005 |
Sato T, Esaki M, Fernandez JM, Endo T. Comparison of the protein-unfolding pathways between mitochondrial protein import and atomic-force microscopy measurements. Proceedings of the National Academy of Sciences of the United States of America. 102: 17999-8004. PMID 16326810 DOI: 10.1073/pnas.0504495102 |
1 |
|
| 2005 |
Fernandez JM. Fingerprinting single molecules in vivo. Biophysical Journal. 89: 3676-7. PMID 16319078 DOI: 10.1529/biophysj.105.072223 |
1 |
|
| 2005 |
Ainavarapu SR, Li L, Badilla CL, Fernandez JM. Ligand binding modulates the mechanical stability of dihydrofolate reductase. Biophysical Journal. 89: 3337-44. PMID 16100277 DOI: 10.1529/biophysj.105.062034 |
1 |
|
| 2005 |
Sarkar A, Caamano S, Fernandez JM. The elasticity of individual titin PEVK exons measured by single molecule atomic force microscopy. The Journal of Biological Chemistry. 280: 6261-4. PMID 15632200 DOI: 10.1074/jbc.C400573200 |
1 |
|
| 2005 |
Li L, Huang HH, Badilla CL, Fernandez JM. Mechanical unfolding intermediates observed by single-molecule force spectroscopy in a fibronectin type III module. Journal of Molecular Biology. 345: 817-26. PMID 15588828 DOI: 10.1016/j.jmb.2004.11.021 |
1 |
|
| 2004 |
Sarkar A, Robertson RB, Fernandez JM. Simultaneous atomic force microscope and fluorescence measurements of protein unfolding using a calibrated evanescent wave. Proceedings of the National Academy of Sciences of the United States of America. 101: 12882-6. PMID 15326308 DOI: 10.1073/pnas.0403534101 |
1 |
|
| 2004 |
Schlierf M, Li H, Fernandez JM. The unfolding kinetics of ubiquitin captured with single-molecule force-clamp techniques. Proceedings of the National Academy of Sciences of the United States of America. 101: 7299-304. PMID 15123816 DOI: 10.1073/pnas.0400033101 |
1 |
|
| 2004 |
Fernandez JM, Li H. Force-clamp spectroscopy monitors the folding trajectory of a single protein. Science (New York, N.Y.). 303: 1674-8. PMID 15017000 DOI: 10.1126/science.1092497 |
1 |
|
| 2003 |
Li H, Fernandez JM. Mechanical design of the first proximal Ig domain of human cardiac titin revealed by single molecule force spectroscopy. Journal of Molecular Biology. 334: 75-86. PMID 14596801 DOI: 10.1016/j.jmb.2003.09.036 |
1 |
|
| 2003 |
Marszalek PE, Oberhauser AF, Li H, Fernandez JM. The force-driven conformations of heparin studied with single molecule force microscopy. Biophysical Journal. 85: 2696-704. PMID 14507732 DOI: 10.1016/S0006-3495(03)74692-X |
1 |
|
| 2003 |
Kenniston JA, Baker TA, Fernandez JM, Sauer RT. Linkage between ATP consumption and mechanical unfolding during the protein processing reactions of an AAA+ degradation machine. Cell. 114: 511-20. PMID 12941278 DOI: 10.1016/S0092-8674(03)00612-3 |
1 |
|
| 2003 |
Carrion-Vazquez M, Li H, Lu H, Marszalek PE, Oberhauser AF, Fernandez JM. The mechanical stability of ubiquitin is linkage dependent. Nature Structural Biology. 10: 738-43. PMID 12923571 DOI: 10.1038/nsb965 |
1 |
|
| 2002 |
Linke WA, Fernandez JM. Cardiac titin: molecular basis of elasticity and cellular contribution to elastic and viscous stiffness components in myocardium. Journal of Muscle Research and Cell Motility. 23: 483-97. PMID 12785099 DOI: 10.1023/A:1023462507254 |
1 |
|
| 2002 |
Li H, Linke WA, Oberhauser AF, Carrion-Vazquez M, Kerkvliet JG, Lu H, Marszalek PE, Fernandez JM. Reverse engineering of the giant muscle protein titin. Nature. 418: 998-1002. PMID 12198551 DOI: 10.1038/nature00938 |
1 |
|
| 2002 |
Linke WA, Kulke M, Li H, Fujita-Becker S, Neagoe C, Manstein DJ, Gautel M, Fernandez JM. PEVK domain of titin: an entropic spring with actin-binding properties. Journal of Structural Biology. 137: 194-205. PMID 12064946 DOI: 10.1006/jsbi.2002.4468 |
1 |
|
| 2002 |
Oberhauser AF, Badilla-Fernandez C, Carrion-Vazquez M, Fernandez JM. The mechanical hierarchies of fibronectin observed with single-molecule AFM Journal of Molecular Biology. 319: 433-447. PMID 12051919 DOI: 10.1016/S0022-2836(02)00306-6 |
1 |
|
| 2002 |
Marszalek PE, Li H, Oberhauser AF, Fernandez JM. Chair-boat transitions in single polysaccharide molecules observed with force-ramp AFM Proceedings of the National Academy of Sciences of the United States of America. 99: 4278-4283. PMID 11917130 DOI: 10.1073/pnas.072435699 |
1 |
|
| Show low-probability matches. |