Sergey N. Savinov, Ph.D. - Publications

Affiliations: 
Yale University, New Haven, CT 

9/45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Rasapalli S, Sammeta VR, Murphy ZF, Huang Y, Boerth JA, Golen JA, Savinov SN. Synthesis of C-Ring-Substituted Vasicinones and Luotonins via Regioselective Aza-Nazarov Cyclization of Quinazolinonyl Enones. Organic Letters. PMID 31800251 DOI: 10.1021/Acs.Orglett.9B03586  0.343
2002 Smith AB, Savinov SN, Manjappara UV, Chaiken IM. Peptide-small molecule hybrids via orthogonal deprotection-chemoselective conjugation to cysteine-anchored scaffolds. A model study. Organic Letters. 4: 4041-4. PMID 12423081 DOI: 10.1021/Ol026736D  0.301
2002 Savinov SN, Austin DJ. Diastereofacial solid phase synthesis and self-promoted cleavage of a [2.2.1] bicyclic diversity scaffold. Organic Letters. 4: 1419-22. PMID 11975593 DOI: 10.1021/Ol017264Q  0.622
2002 Savinov SN, Austin DJ. Modular evolution of a chiral auxiliary for the 1,3-dipolar cycloaddition of isomünchnones with vinyl ethers. Organic Letters. 4: 1415-8. PMID 11975592 DOI: 10.1021/Ol017263Y  0.577
2001 Savinov SN, Austin DJ. The cloning of human genes using cDNA phage display and small-molecule chemical probes. Combinatorial Chemistry & High Throughput Screening. 4: 593-7. PMID 11562262 DOI: 10.2174/1386207013330814  0.463
1999 Savinov SN, Austin DJ. The diastereoselective cycloaddition of vinyl ethers with isomunchnones Chemical Communications. 1813-1814. DOI: 10.1039/A903381E  0.551
1998 Whitehouse DL, Nelson KH, Savinov SN, Löwe RS, Austin DJ. A metathetical cycloaddition-cycloreversion approach to the formation of furan scaffold libraries. Bioorganic & Medicinal Chemistry. 6: 1273-82. PMID 9784868 DOI: 10.1016/S0968-0896(98)00115-1  0.598
1997 Whitehouse DL, Savinov SN, Austin DJ. An improved synthesis and selective coupling of a hydroxy based photolabile linker for solid phase organic synthesis Tetrahedron Letters. 38: 7851-7852. DOI: 10.1016/S0040-4039(97)10133-2  0.576
1997 Whitehouse DL, Nelson KH, Savinov SN, Austin DJ. A chemoselective rhodium(II) mediated solid phase 1,3-dipolar cycloaddition and its application to a thermally self-cleaving puran scaffold Tetrahedron Letters. 38: 7139-7142. DOI: 10.1016/S0040-4039(97)01768-1  0.616
Low-probability matches (unlikely to be authored by this person)
2019 Sivappa R, Sammeta VR, Huang Y, Golen JA, Savinov SN. Facile synthesis of 3-substituted imidazo[1,2-]pyridines through formimidamide chemistry. Rsc Advances. 9: 29659-29664. PMID 35531553 DOI: 10.1039/c9ra05841a  0.223
2004 Horswill AR, Savinov SN, Benkovic SJ. A systematic method for identifying small-molecule modulators of protein-protein interactions. Proceedings of the National Academy of Sciences of the United States of America. 101: 15591-6. PMID 15498867 DOI: 10.1073/Pnas.0406999101  0.207
2021 Rasapalli S, Reddy Sammeta V, Murphy ZF, Golen JA, Agama K, Pommier Y, Savinov SN. Design and Synthesis of C-Aryl Angular Luotonins via One-Pot Aza-Nazarov-Friedlander Sequence and Their Topo-I Inhibition Studies Along with C-Aryl Vasicinones and Luotonins. Bioorganic & Medicinal Chemistry Letters. 127998. PMID 33794318 DOI: 10.1016/j.bmcl.2021.127998  0.199
2005 Naumann TA, Savinov SN, Benkovic SJ. Engineering an affinity tag for genetically encoded cyclic peptides. Biotechnology and Bioengineering. 92: 820-30. PMID 16155946 DOI: 10.1002/Bit.20644  0.145
2015 Conley JM, Meyer JM, Nuss AB, Doyle TB, Savinov SN, Hill CA, Watts VJ. Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti. The Journal of Pharmacology and Experimental Therapeutics. 352: 53-60. PMID 25332454 DOI: 10.1124/Jpet.114.219717  0.14
2024 Cruz KG, Hill Eron M, Makhaik S, Savinov S, Hardy JA. A Non-Active-Site Inhibitor with Selectivity for Zika Virus NS2B-NS3 Protease. Acs Infectious Diseases. PMID 38265226 DOI: 10.1021/acsinfecdis.3c00330  0.124
2022 Zhang Y, Kao PL, Rampal A, Mafu S, Savinov S, Ma LJ. High-Throughput Screening Assays to Identify Plant Natural Products with Antifungal Properties Against Fusarium oxysporum. Methods in Molecular Biology (Clifton, N.J.). 2391: 171-184. PMID 34686985 DOI: 10.1007/978-1-0716-1795-3_14  0.119
2018 Minsky BB, Abzalimov RR, Niu C, Zhao Y, Kirsch Z, Dubin PL, Savinov SN, Kaltashov IA. Mass spectrometry reveals a multi-faceted role of glycosaminoglycan chains in factor Xa inactivation by antithrombin. Biochemistry. PMID 29999301 DOI: 10.1021/Acs.Biochem.8B00199  0.113
2019 Lorès P, Dacheux D, Kherraf ZE, Nsota Mbango JF, Coutton C, Stouvenel L, Ialy-Radio C, Amiri-Yekta A, Whitfield M, Schmitt A, Cazin C, Givelet M, Ferreux L, Fourati Ben Mustapha S, Halouani L, ... ... Savinov SN, et al. Mutations in TTC29, Encoding an Evolutionarily Conserved Axonemal Protein, Result in Asthenozoospermia and Male Infertility. American Journal of Human Genetics. PMID 31735292 DOI: 10.1016/j.ajhg.2019.10.007  0.112
2018 Tubeleviciute-Aydin A, Zhou L, Sharma G, Soni IV, Savinov SN, Hardy JA, LeBlanc AC. Rare human Caspase-6-R65W and Caspase-6-G66R variants identify a novel regulatory region of Caspase-6 activity. Scientific Reports. 8: 4428. PMID 29535332 DOI: 10.1038/S41598-018-22283-Z  0.111
2020 Niu C, Zhao Y, Bobst CE, Savinov SN, Kaltashov IA. Identification of protein recognition elements within heparin chains using enzymatic foot-printing in solution and on-line SEC/MS. Analytical Chemistry. PMID 32347711 DOI: 10.1021/Acs.Analchem.0C00115  0.11
2019 Liang C, Savinov SN, Fejzo J, Eyles SJ, Chen J. Modulation of Amyloid-β42 Conformation by Small Molecules Through Non-Specific Binding. Journal of Chemical Theory and Computation. PMID 31476124 DOI: 10.1021/Acs.Jctc.9B00599  0.109
2003 Savinov SN, Hirschmann R, Benkovic SJ, Smith AB. Investigation of an antibody-ligase. Evidence for strain-induced catalysis. Bioorganic & Medicinal Chemistry Letters. 13: 1321-4. PMID 12657273 DOI: 10.1016/S0960-894X(03)00123-9  0.108
2009 Koley D, Colón OC, Savinov SN. Chemoselective nitration of phenols with tert-butyl nitrite in solution and on solid support. Organic Letters. 11: 4172-5. PMID 19697919 DOI: 10.1021/ol901731w  0.107
2018 Lorès P, Coutton C, El Khouri E, Stouvenel L, Givelet M, Thomas L, Rode B, Schmitt A, Louis B, Sakheli Z, Chaudhry M, Fernandez-Gonzales A, Mitsialis A, Dacheux D, Wolf JP, ... ... Savinov SN, et al. Homozygous missense mutation L673P in Adenylate Kinase 7 (AK7) leads to primary male infertility and Multiple Morphological Anomalies of the Flagella but not to Primary Ciliary Dyskinesia. Human Molecular Genetics. PMID 29365104 DOI: 10.1093/Hmg/Ddy034  0.1
2023 Lynch A, Pearson P, Savinov SN, Li AY, Rich SM. Lactate Dehydrogenase Inhibitors Suppress Growth In Vitro. Pathogens (Basel, Switzerland). 12. PMID 37513809 DOI: 10.3390/pathogens12070962  0.084
2015 Escoffier J, Lee HC, Yassine S, Zouari R, Martinez G, Karaouzène T, Coutton C, Kherraf ZE, Halouani L, Triki C, Nef S, Thierry-Mieg N, Savinov SN, Fissore R, Ray PF, et al. Homozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW binding protein PAWP. Human Molecular Genetics. PMID 26721930 DOI: 10.1093/Hmg/Ddv617  0.082
2017 Savinov SN, Heuck AP. Interaction of Cholesterol with Perfringolysin O: What Have We Learned from Functional Analysis? Toxins. 9. PMID 29168745 DOI: 10.3390/Toxins9120381  0.081
2019 Kaltashov IA, El-Khoury A, Ren C, Savinov SN. Ruthenium coordination preferences in imidazole-containing systems revealed by electrospray ionization mass spectrometry and molecular modeling: possible cues for the surprising stability of the Ru (III)/tris (hydroxymethyl)-aminomethane/imidazole complexes. Journal of Mass Spectrometry : Jms. PMID 31508870 DOI: 10.1002/Jms.4435  0.076
2012 Verhoeven KD, Altstadt OC, Savinov SN. Intracellular detection and evolution of site-specific proteases using a genetic selection system. Applied Biochemistry and Biotechnology. 166: 1340-54. PMID 22270548 DOI: 10.1007/s12010-011-9522-6  0.075
2010 Bucks ME, Savinov SN. Direct evaluation of cellular internalization rates using chromogenic disulfides. Molecular Biosystems. 6: 1176-9. PMID 20405082 DOI: 10.1039/c003969a  0.074
2020 Chuchina V, Gubal A, Lyalkin Y, Glumov O, Trefilov I, Sorokina A, Savinov S, Solovyev N, Ganeev A. A study of matrix and admixture elements in fluorine-rich ionic conductors by pulsed glow discharge mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 34: e8786. PMID 32182379 DOI: 10.1002/rcm.8786  0.074
2021 Taskaev S, Berendeev E, Bikchurina M, Bykov T, Kasatov D, Kolesnikov I, Koshkarev A, Makarov A, Ostreinov G, Porosev V, Savinov S, Shchudlo I, Sokolova E, Sorokin I, Sycheva T, et al. Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target. Biology. 10. PMID 33919153 DOI: 10.3390/biology10050350  0.073
2007 Xie H, Ng D, Savinov SN, Dey B, Kwong PD, Wyatt R, Smith AB, Hendrickson WA. Structure-activity relationships in the binding of chemically derivatized CD4 to gp120 from human immunodeficiency virus Journal of Medicinal Chemistry. 50: 4898-4908. PMID 17803292 DOI: 10.1021/Jm070564E  0.072
2019 Elfawal MA, Savinov SN, Aroian RV. Drug Screening for Discovery of Broad-spectrum Agents for Soil-transmitted Nematodes. Scientific Reports. 9: 12347. PMID 31451730 DOI: 10.1038/S41598-019-48720-1  0.071
2019 Marcinko TM, Liang C, Savinov S, Chen J, Vachet RW. Structural heterogeneity in the pre-amyloid oligomers of β-2-microglobulin. Journal of Molecular Biology. PMID 31711963 DOI: 10.1016/J.Jmb.2019.10.030  0.07
2010 Datta S, Bucks ME, Koley D, Lim PX, Savinov SN. Functional profiling of p53-binding sites in Hdm2 and Hdmx using a genetic selection system. Bioorganic & Medicinal Chemistry. 18: 6099-108. PMID 20638853 DOI: 10.1016/j.bmc.2010.06.053  0.064
2017 Dagbay KB, Bolik-Coulon N, Savinov SN, Hardy JA. Caspase-6 Undergoes a Distinct Helix-Strand Interconversion Upon Substrate Binding. The Journal of Biological Chemistry. PMID 28154009 DOI: 10.1074/Jbc.M116.773499  0.061
2019 Okerberg ES, Dagbay KB, Green JL, Soni I, Aban A, Nomanbhoy TK, Savinov SN, Hardy JA, Kozarich JW. Chemoproteomics Using Nucleotide Acyl Phosphates Reveals an ATP-Binding Site at the Dimer Interface of Procaspase-6. Biochemistry. PMID 31095371 DOI: 10.1021/Acs.Biochem.9B00290  0.06
2013 Eggler AL, Savinov SN. Chemical and biological mechanisms of phytochemical activation of Nrf2 and importance in disease prevention. Recent Advances in Phytochemistry. 43: 121-155. PMID 26855455 DOI: 10.1007/978-3-319-00581-2_7  0.057
2014 Eissler CL, Mazón G, Powers BL, Savinov SN, Symington LS, Hall MC. The Cdk/cDc14 module controls activation of the Yen1 holliday junction resolvase to promote genome stability. Molecular Cell. 54: 80-93. PMID 24631283 DOI: 10.1016/J.Molcel.2014.02.012  0.048
2015 Chen Y, Savinov SN, Mielech AM, Cao T, Baker SC, Mesecar AD. X-ray Structural and Functional Studies of the Three Tandemly-Linked Domains of Nsp3 from Murine Hepatitis Virus Reveal Conserved Functions. The Journal of Biological Chemistry. PMID 26296883 DOI: 10.1074/Jbc.M115.662130  0.047
2020 Zhang Y, Yang H, Turra D, Zhou S, Ayhan DH, DeIulio GA, Guo L, Broz K, Wiederhold N, Coleman JJ, Donnell KO, Youngster I, McAdam AJ, Savinov S, Shea T, et al. The genome of opportunistic fungal pathogen Fusarium oxysporum carries a unique set of lineage-specific chromosomes. Communications Biology. 3: 50. PMID 32005944 DOI: 10.1038/s42003-020-0770-2  0.045
2016 Fatunmbi O, Abzalimov R, Savinov SN, Gershenson A, Kaltashov IA. Haptoglobin interactions with monomeric globin species: insights from molecular modeling and native electrospray ionization mass spectrometry. Biochemistry. PMID 26937685 DOI: 10.1021/Acs.Biochem.5B00807  0.038
2018 Lorès P, Coutton C, Khouri EE, Stouvenel L, Givelet M, Thomas L, Rode B, Schmitt A, Louis B, Sakheli Z, Chaudhry M, Fernandez-Gonzales A, Mitsialis A, Dacheux D, Wolf JP, ... ... Savinov SN, et al. Homozygous missense mutation L673P in adenylate kinase 7 (AK7) leads to primary male infertility and multiple morphological anomalies of the flagella but not to primary ciliary dyskinesia. Human Molecular Genetics. PMID 30517620 DOI: 10.1093/hmg/ddy368  0.031
2021 Dymova M, Dmitrieva M, Kuligina E, Richter V, Savinov S, Shchudlo I, Sycheva T, Taskaeva I, Taskaev S. Method of Measuring High-LET Particles Dose. Radiation Research. 196: 192-196. PMID 34019668 DOI: 10.1667/RADE-21-00015.1  0.022
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