Year |
Citation |
Score |
2006 |
Peters U, Cherian J, Kim JH, Kwok BH, Kapoor TM. Probing cell-division phenotype space and Polo-like kinase function using small molecules. Nature Chemical Biology. 2: 618-26. PMID 17028580 DOI: 10.1038/Nchembio826 |
0.314 |
|
2006 |
Kwok BH, Kapitein LC, Kim JH, Peterman EJ, Schmidt CF, Kapoor TM. Allosteric inhibition of kinesin-5 modulates its processive directional motility. Nature Chemical Biology. 2: 480-5. PMID 16892050 DOI: 10.1038/Nchembio812 |
0.343 |
|
2004 |
Lin S, Yang ZQ, Kwok BH, Koldobskiy M, Crews CM, Danishefsky SJ. Total synthesis of TMC-95A and -B via a new reaction leading to Z-enamides. Some preliminary findings as to SAR. Journal of the American Chemical Society. 126: 6347-55. PMID 15149232 DOI: 10.1021/Ja049821K |
0.5 |
|
2003 |
Yang ZQ, Kwok BH, Lin S, Koldobskiy MA, Crews CM, Danishefsky SJ. Simplified synthetic TMC-95A/B analogues retain the potency of proteasome inhibitory activity. Chembiochem : a European Journal of Chemical Biology. 4: 508-13. PMID 12794861 DOI: 10.1002/Cbic.200300560 |
0.55 |
|
2002 |
Ndubuisil MI, Kwok BH, Vervoort J, Koh BD, Elofsson M, Crews CM. Characterization of a novel mammalian phosphatase having sequence similarity to Schizosaccharomyces pombe PHO2 and Saccharomyces cerevisiae PHO13. Biochemistry. 41: 7841-8. PMID 12056916 DOI: 10.1021/Bi0255064 |
0.465 |
|
2001 |
Kwok BH, Koh B, Ndubuisi MI, Elofsson M, Crews CM. The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase. Chemistry & Biology. 8: 759-66. PMID 11514225 DOI: 10.1016/S1074-5521(01)00049-7 |
0.559 |
|
1999 |
Meng L, Mohan R, Kwok BH, Elofsson M, Sin N, Crews CM. Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity. Proceedings of the National Academy of Sciences of the United States of America. 96: 10403-8. PMID 10468620 DOI: 10.1073/Pnas.96.18.10403 |
0.617 |
|
1999 |
Sin N, Kim KB, Elofsson M, Meng L, Auth H, Kwok BH, Crews CM. Total synthesis of the potent proteasome inhibitor epoxomicin: a useful tool for understanding proteasome biology. Bioorganic & Medicinal Chemistry Letters. 9: 2283-8. PMID 10465562 DOI: 10.1016/S0960-894X(99)00376-5 |
0.591 |
|
1999 |
Meng L, Kwok BH, Sin N, Crews CM. Eponemycin exerts its antitumor effect through the inhibition of proteasome function. Cancer Research. 59: 2798-801. PMID 10383134 |
0.597 |
|
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