Benjamin H. Kwok, Ph.D. - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
organic synthesis, pharmacology, molecular biology

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Laflamme G, Tremblay-Boudreault T, Roy MA, Andersen P, Bonneil É, Atchia K, Thibault P, D'Amours D, Kwok BH. Structural maintenance of chromosome (SMC) proteins link microtubule stability to genome integrity. The Journal of Biological Chemistry. 289: 27418-31. PMID 25135640 DOI: 10.1074/jbc.M114.569608  0.8
2014 Arora K, Talje L, Asenjo AB, Andersen P, Atchia K, Joshi M, Sosa H, Allingham JS, Kwok BH. KIF14 binds tightly to microtubules and adopts a rigor-like conformation. Journal of Molecular Biology. 426: 2997-3015. PMID 24949858 DOI: 10.1016/j.jmb.2014.05.030  0.8
2014 Talje L, Ben El Kadhi K, Atchia K, Tremblay-Boudreault T, Carreno S, Kwok BH. DHTP is an allosteric inhibitor of the kinesin-13 family of microtubule depolymerases. Febs Letters. 588: 2315-20. PMID 24859087 DOI: 10.1016/j.febslet.2014.05.024  0.8
2013 Solinet S, Mahmud K, Stewman SF, Ben El Kadhi K, Decelle B, Talje L, Ma A, Kwok BH, Carreno S. The actin-binding ERM protein Moesin binds to and stabilizes microtubules at the cell cortex. The Journal of Cell Biology. 202: 251-60. PMID 23857773 DOI: 10.1083/jcb.201304052  0.8
2008 Kapitein LC, Kwok BH, Weinger JS, Schmidt CF, Kapoor TM, Peterman EJ. Microtubule cross-linking triggers the directional motility of kinesin-5. The Journal of Cell Biology. 182: 421-8. PMID 18678707 DOI: 10.1083/jcb.200801145  0.8
2008 Woo EM, Fenyo D, Kwok BH, Funabiki H, Chait BT. Efficient identification of phosphorylation by mass spectrometric phosphopeptide fingerprinting. Analytical Chemistry. 80: 2419-25. PMID 18321079 DOI: 10.1021/ac702059p  0.8
2007 Kwok BH, Kapoor TM. Microtubule flux: drivers wanted. Current Opinion in Cell Biology. 19: 36-42. PMID 17174541 DOI: 10.1016/j.ceb.2006.12.003  0.8
2006 Peters U, Cherian J, Kim JH, Kwok BH, Kapoor TM. Probing cell-division phenotype space and Polo-like kinase function using small molecules. Nature Chemical Biology. 2: 618-26. PMID 17028580 DOI: 10.1038/nchembio826  0.8
2006 Kwok BH, Kapitein LC, Kim JH, Peterman EJ, Schmidt CF, Kapoor TM. Allosteric inhibition of kinesin-5 modulates its processive directional motility. Nature Chemical Biology. 2: 480-5. PMID 16892050 DOI: 10.1038/nchembio812  0.8
2005 Kapitein LC, Peterman EJ, Kwok BH, Kim JH, Kapoor TM, Schmidt CF. The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks. Nature. 435: 114-8. PMID 15875026 DOI: 10.1038/nature03503  0.8
2004 Kwok BH, Yang JG, Kapoor TM. The rate of bipolar spindle assembly depends on the microtubule-gliding velocity of the mitotic kinesin Eg5. Current Biology : Cb. 14: 1783-8. PMID 15458652 DOI: 10.1016/j.cub.2004.09.052  0.8
2004 Lin S, Yang ZQ, Kwok BH, Koldobskiy M, Crews CM, Danishefsky SJ. Total synthesis of TMC-95A and -B via a new reaction leading to Z-enamides. Some preliminary findings as to SAR. Journal of the American Chemical Society. 126: 6347-55. PMID 15149232 DOI: 10.1021/ja049821k  0.8
2003 Han YG, Kwok BH, Kernan MJ. Intraflagellar transport is required in Drosophila to differentiate sensory cilia but not sperm. Current Biology : Cb. 13: 1679-86. PMID 14521833 DOI: 10.1016/j.cub.2003.08.034  0.8
2003 Yang ZQ, Kwok BH, Lin S, Koldobskiy MA, Crews CM, Danishefsky SJ. Simplified synthetic TMC-95A/B analogues retain the potency of proteasome inhibitory activity. Chembiochem : a European Journal of Chemical Biology. 4: 508-13. PMID 12794861 DOI: 10.1002/cbic.200300560  0.8
2002 Ndubuisil MI, Kwok BH, Vervoort J, Koh BD, Elofsson M, Crews CM. Characterization of a novel mammalian phosphatase having sequence similarity to Schizosaccharomyces pombe PHO2 and Saccharomyces cerevisiae PHO13. Biochemistry. 41: 7841-8. PMID 12056916 DOI: 10.1021/bi0255064  0.8
2001 Kwok BH, Koh B, Ndubuisi MI, Elofsson M, Crews CM. The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase. Chemistry & Biology. 8: 759-66. PMID 11514225 DOI: 10.1016/S1074-5521(01)00049-7  0.8
1999 Meng L, Mohan R, Kwok BH, Elofsson M, Sin N, Crews CM. Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity. Proceedings of the National Academy of Sciences of the United States of America. 96: 10403-8. PMID 10468620 DOI: 10.1073/pnas.96.18.10403  0.8
1999 Sin N, Kim KB, Elofsson M, Meng L, Auth H, Kwok BH, Crews CM. Total synthesis of the potent proteasome inhibitor epoxomicin: a useful tool for understanding proteasome biology. Bioorganic & Medicinal Chemistry Letters. 9: 2283-8. PMID 10465562 DOI: 10.1016/S0960-894X(99)00376-5  0.8
1999 Meng L, Kwok BH, Sin N, Crews CM. Eponemycin exerts its antitumor effect through the inhibition of proteasome function. Cancer Research. 59: 2798-801. PMID 10383134  0.8
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