Dennis Buckley, Ph.D. - Publications

Yale University, New Haven, CT
organic synthesis, pharmacology, molecular biology

9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Gustafson JL, Neklesa TK, Cox CS, Roth AG, Buckley DL, Tae HS, Sundberg TB, Stagg DB, Hines J, McDonnell DP, Norris JD, Crews CM. Small-Molecule-Mediated Degradation of the Androgen Receptor Through Hydrophobic Tagging. Angewandte Chemie (International Ed. in English). PMID 26083457 DOI: 10.1002/Anie.201503720  0.48
2015 Bondeson DP, Mares A, Smith IE, Ko E, Campos S, Miah AH, Mulholland KE, Routly N, Buckley DL, Gustafson JL, Zinn N, Grandi P, Shimamura S, Bergamini G, Faelth-Savitski M, et al. Catalytic in vivo protein knockdown by small-molecule PROTACs. Nature Chemical Biology. 11: 611-7. PMID 26075522 DOI: 10.1038/Nchembio.1858  0.48
2015 Buckley DL, Raina K, Darricarrere N, Hines J, Gustafson JL, Smith IE, Miah AH, Harling JD, Crews CM. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. Acs Chemical Biology. PMID 26070106 DOI: 10.1021/Acschembio.5B00442  0.48
2014 Singel SM, Cornelius C, Zaganjor E, Batten K, Sarode VR, Buckley DL, Peng Y, John GB, Li HC, Sadeghi N, Wright WE, Lum L, Corson TW, Shay JW. KIF14 promotes AKT phosphorylation and contributes to chemoresistance in triple-negative breast cancer. Neoplasia (New York, N.Y.). 16: 247-56, 256.e2. PMID 24784001 DOI: 10.1016/J.Neo.2014.03.008  0.48
2014 Buckley DL, Crews CM. Small-molecule control of intracellular protein levels through modulation of the ubiquitin proteasome system. Angewandte Chemie (International Ed. in English). 53: 2312-30. PMID 24459094 DOI: 10.1002/Anie.201307761  0.48
2012 Van Molle I, Thomann A, Buckley DL, So EC, Lang S, Crews CM, Ciulli A. Dissecting fragment-based lead discovery at the von Hippel-Lindau protein:hypoxia inducible factor 1α protein-protein interface. Chemistry & Biology. 19: 1300-12. PMID 23102223 DOI: 10.1016/J.Chembiol.2012.08.015  0.48
2012 Buckley DL, Gustafson JL, Van Molle I, Roth AG, Tae HS, Gareiss PC, Jorgensen WL, Ciulli A, Crews CM. Small-molecule inhibitors of the interaction between the E3 ligase VHL and HIF1α. Angewandte Chemie (International Ed. in English). 51: 11463-7. PMID 23065727 DOI: 10.1002/Anie.201206231  0.48
2012 Buckley DL, Van Molle I, Gareiss PC, Tae HS, Michel J, Noblin DJ, Jorgensen WL, Ciulli A, Crews CM. Targeting the von Hippel-Lindau E3 ubiquitin ligase using small molecules to disrupt the VHL/HIF-1α interaction. Journal of the American Chemical Society. 134: 4465-8. PMID 22369643 DOI: 10.1021/Ja209924V  0.48
2011 Buckley DL, Corson TW, Aberle N, Crews CM. HIV protease-mediated activation of sterically capped proteasome inhibitors and substrates. Journal of the American Chemical Society. 133: 698-700. PMID 21186803 DOI: 10.1021/Ja109377P  0.48
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