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Sudarshan Rajagopal, Ph.D. - Publications

Affiliations: 
University of Chicago, Chicago, IL 
Area:
dynamic X-ray diffraction studies of macromolecules; natural and engineered photoreceptors
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Ma Z, Mao L, Rajagopal S. Hemodynamic Characterization of Rodent Models of Pulmonary Arterial Hypertension. Journal of Visualized Experiments : Jove. PMID 27167679 DOI: 10.3791/53335  0.88
2016 Dahhan T, Kaushik SS, He M, Mammarappallil JG, Tapson VF, McAdams HP, Sporn TA, Driehuys B, Rajagopal S. Abnormalities in hyperpolarized (129)Xe magnetic resonance imaging and spectroscopy in two patients with pulmonary vascular disease. Pulmonary Circulation. 6: 126-31. PMID 27162620 DOI: 10.1086/685110  0.88
2016 Smith JS, Rajagopal S. The β-arrestins: Multifunctional regulators of G protein-coupled receptors. The Journal of Biological Chemistry. PMID 26984408 DOI: 10.1074/jbc.R115.713313  0.88
2016 Parikh KS, Rajagopal S, Fortin T, Tapson VF, Poms AD. Safety and Tolerability of High-dose Inhaled Treprostinil in Pulmonary Hypertension. Journal of Cardiovascular Pharmacology. PMID 26828324 DOI: 10.1097/FJC.0000000000000357  0.88
2015 Forsha D, Risum N, Rajagopal S, Dolgner S, Hornik C, Barnhart H, Kisslo J, Barker P. The influence of angle of insonation and target depth on speckle-tracking strain. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 28: 580-6. PMID 25655402 DOI: 10.1016/j.echo.2014.12.015  0.88
2015 Abdullah N, Chu S, Rajagopal S, Tung A, Kwong-Man Y. Exploring libraries' efforts in inclusion and outreach activities using social media Libri. 65: 34-47. DOI: 10.1515/libri-2014-0055  0.32
2015 Parikh KS, Rajagopal S, Arges K, Ahmad T, Sivak J, Kaul P, Shah SH, Tapson V, Velazquez EJ, Douglas PS, Samad Z. Use of outcome measures in pulmonary hypertension clinical trials American Heart Journal. DOI: 10.1016/j.ahj.2015.06.010  0.88
2014 Onaran HO, Rajagopal S, Costa T. What is biased efficacy? Defining the relationship between intrinsic efficacy and free energy coupling. Trends in Pharmacological Sciences. 35: 639-47. PMID 25448316 DOI: 10.1016/j.tips.2014.09.010  0.88
2014 Kahsai AW, Rajagopal S, Sun J, Xiao K. Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry. Nature Protocols. 9: 1301-19. PMID 24810039 DOI: 10.1038/nprot.2014.075  0.88
2014 Rajagopal S, Forsha DE, Risum N, Hornik CP, Poms AD, Fortin TA, Tapson VF, Velazquez EJ, Kisslo J, Samad Z. Comprehensive assessment of right ventricular function in patients with pulmonary hypertension with global longitudinal peak systolic strain derived from multiple right ventricular views. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 27: 657-665.e3. PMID 24656881 DOI: 10.1016/j.echo.2014.02.001  0.88
2014 Forsha D, Risum N, Kropf PA, Rajagopal S, Smith PB, Kanter RJ, Samad Z, Sogaard P, Barker P, Kisslo J. Right ventricular mechanics using a novel comprehensive three-view echocardiographic strain analysis in a normal population. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 27: 413-22. PMID 24508364 DOI: 10.1016/j.echo.2013.12.018  0.88
2014 Bhuvaneswari J, Mareeswaran PM, Anandababu K, Rajagopal S. The switching of a Rhenium(i) complex from turn-off to turn-on sensor system through protein binding Rsc Advances. 4: 34659-34668. DOI: 10.1039/c4ra05464d  0.01
2013 Rajagopal S, Bassoni DL, Campbell JJ, Gerard NP, Gerard C, Wehrman TS. Biased agonism as a mechanism for differential signaling by chemokine receptors. The Journal of Biological Chemistry. 288: 35039-48. PMID 24145037 DOI: 10.1074/jbc.M113.479113  0.88
2013 Rajagopal S. Quantifying biased agonism: understanding the links between affinity and efficacy. Nature Reviews. Drug Discovery. 12: 483. PMID 23681006 DOI: 10.1038/nrd3954-c1  0.88
2012 Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, et al. Global phosphorylation analysis of β-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR) (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 34 (15299-15304) doi:10.1073/pnas.1008461107) Proceedings of the National Academy of Sciences of the United States of America. 109: 13464. DOI: 10.1073/pnas.1211889109  0.88
2011 Nobles KN, Xiao K, Ahn S, Shukla AK, Lam CM, Rajagopal S, Strachan RT, Huang TY, Bressler EA, Hara MR, Shenoy SK, Gygi SP, Lefkowitz RJ. Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin. Science Signaling. 4: ra51. PMID 21868357 DOI: 10.1126/scisignal.2001707  0.88
2011 Hara MR, Kovacs JJ, Whalen EJ, Rajagopal S, Strachan RT, Grant W, Towers AJ, Williams B, Lam CM, Xiao K, Shenoy SK, Gregory SG, Ahn S, Duckett DR, Lefkowitz RJ. A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1. Nature. 477: 349-53. PMID 21857681 DOI: 10.1038/nature10368  0.88
2011 Kahsai AW, Xiao K, Rajagopal S, Ahn S, Shukla AK, Sun J, Oas TG, Lefkowitz RJ. Multiple ligand-specific conformations of the β2-adrenergic receptor. Nature Chemical Biology. 7: 692-700. PMID 21857662 DOI: 10.1038/nchembio.634  0.88
2011 Rajagopal S, Ahn S, Rominger DH, Gowen-MacDonald W, Lam CM, Dewire SM, Violin JD, Lefkowitz RJ. Quantifying ligand bias at seven-transmembrane receptors. Molecular Pharmacology. 80: 367-77. PMID 21610196 DOI: 10.1124/mol.111.072801  0.88
2011 Whalen EJ, Rajagopal S, Lefkowitz RJ. Therapeutic potential of β-arrestin- and G protein-biased agonists. Trends in Molecular Medicine. 17: 126-39. PMID 21183406 DOI: 10.1016/j.molmed.2010.11.004  0.88
2010 Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, et al. Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR). Proceedings of the National Academy of Sciences of the United States of America. 107: 15299-304. PMID 20686112 DOI: 10.1073/pnas.1008461107  0.88
2010 Rajagopal S, Rajagopal K, Lefkowitz RJ. Teaching old receptors new tricks: biasing seven-transmembrane receptors. Nature Reviews. Drug Discovery. 9: 373-86. PMID 20431569 DOI: 10.1038/nrd3024  0.88
2010 Rajagopal S, Kim J, Ahn S, Craig S, Lam CM, Gerard NP, Gerard C, Lefkowitz RJ. Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7. Proceedings of the National Academy of Sciences of the United States of America. 107: 628-32. PMID 20018651 DOI: 10.1073/pnas.0912852107  0.88
2007 Rajagopal S, Kent SB. Total chemical synthesis and biophysical characterization of the minimal isoform of the KChIP2 potassium channel regulatory subunit. Protein Science : a Publication of the Protein Society. 16: 2056-64. PMID 17660260 DOI: 10.1110/ps.072876107  0.88
2005 Ihee H, Rajagopal S, Srajer V, Pahl R, Anderson S, Schmidt M, Schotte F, Anfinrud PA, Wulff M, Moffat K. Visualizing reaction pathways in photoactive yellow protein from nanoseconds to seconds. Proceedings of the National Academy of Sciences of the United States of America. 102: 7145-50. PMID 15870207 DOI: 10.1073/pnas.0409035102  0.88
2005 Rajagopal S, Anderson S, Srajer V, Schmidt M, Pahl R, Moffat K. A structural pathway for signaling in the E46Q mutant of photoactive yellow protein. Structure (London, England : 1993). 13: 55-63. PMID 15642261 DOI: 10.1016/j.str.2004.10.016  0.88
2004 Rajagopal S, Key JM, Purcell EB, Boerema DJ, Moffat K. Purification and initial characterization of a putative blue light-regulated phosphodiesterase from Escherichia coli. Photochemistry and Photobiology. 80: 542-7. PMID 15453820 DOI: 10.1562/2004-06-16-RA-203  0.88
2004 Rajagopal S, Kostov KS, Moffat K. Analytical trapping: extraction of time-independent structures from time-dependent crystallographic data. Journal of Structural Biology. 147: 211-22. PMID 15450291 DOI: 10.1016/j.jsb.2004.04.007  0.88
2004 Anderson S, Srajer V, Pahl R, Rajagopal S, Schotte F, Anfinrud P, Wulff M, Moffat K. Chromophore conformation and the evolution of tertiary structural changes in photoactive yellow protein. Structure (London, England : 1993). 12: 1039-45. PMID 15274923 DOI: 10.1016/j.str.2004.04.008  0.88
2004 Rajagopal S, Schmidt M, Anderson S, Ihee H, Moffat K. Analysis of experimental time-resolved crystallographic data by singular value decomposition. Acta Crystallographica. Section D, Biological Crystallography. 60: 860-71. PMID 15103131 DOI: 10.1107/S0907444904004160  0.88
2004 Schmidt M, Pahl R, Srajer V, Anderson S, Ren Z, Ihee H, Rajagopal S, Moffat K. Protein kinetics: structures of intermediates and reaction mechanism from time-resolved x-ray data. Proceedings of the National Academy of Sciences of the United States of America. 101: 4799-804. PMID 15041745 DOI: 10.1073/pnas.0305983101  0.88
2003 Schmidt M, Rajagopal S, Ren Z, Moffat K. Application of singular value decomposition to the analysis of time-resolved macromolecular x-ray data. Biophysical Journal. 84: 2112-29. PMID 12609912 DOI: 10.1016/S0006-3495(03)75018-8  0.88
2003 Rajagopal S, Moffat K. Crystal structure of a photoactive yellow protein from a sensor histidine kinase: conformational variability and signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 100: 1649-54. PMID 12563032 DOI: 10.1073/pnas.0336353100  0.88
2003 Crosson S, Rajagopal S, Moffat K. The LOV domain family: photoresponsive signaling modules coupled to diverse output domains. Biochemistry. 42: 2-10. PMID 12515534 DOI: 10.1021/bi026978l  0.88
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