Christopher J. Fischer, Ph.D. - Publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Structural Enzymology, Protein Processing and Folding

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Nguyen B, Hsieh J, Fischer CJ, Lohman TM. Subunit Communication within Dimeric SF1 DNA Helicases. Journal of Molecular Biology. 168578. PMID 38648969 DOI: 10.1016/j.jmb.2024.168578  0.727
2022 Morgan A, Eastlund A, Fischer C, Jardine P. Kinetics of ATP/ADP binding to the gp16 ATPase. Biophysical Journal. PMID 35421388 DOI: 10.1016/j.bpj.2022.04.013  0.802
2020 Morgan A, LeGresley S, Fischer C. Remodeler Catalyzed Nucleosome Repositioning: Influence of Structure and Stability. International Journal of Molecular Sciences. 22. PMID 33374740 DOI: 10.3390/ijms22010076  0.503
2019 Grotemeyer EN, Briggs K, Fischer CJ. Proteins are Not Recruited: A Plea for Better Diction Emerging Trends in Kinetics and Thermodynamics. 1. DOI: 10.36959/672/587  0.528
2018 Briggs K, Al-Ani G, Eastlund A, Fischer CJ. Anisotropy-Based Nucleosome Repositioning Assay. Methods in Molecular Biology (Clifton, N.J.). 1805: 333-347. PMID 29971726 DOI: 10.1007/978-1-4939-8556-2_17  0.817
2018 Morgan AM, LeGresley SE, Briggs K, Al-Ani G, Fischer CJ. Effects of nucleosome stability on remodeler-catalyzed repositioning. Physical Review. E. 97: 032422. PMID 29776169 DOI: 10.1103/Physreve.97.032422  0.832
2018 LeGresley SE, Briggs K, Fischer CJ. Molecular Motor Translocation Kinetics: Application of Monte Carlo Computer Simulations to Determine Microscopic Kinetic Parameters. Bio Systems. PMID 29733888 DOI: 10.1016/J.Biosystems.2018.05.001  0.633
2015 Eastlund A, Al-Ani G, Fischer CJ. Low processivity for DNA translocation by the ISWI molecular motor. Biochimica Et Biophysica Acta. 1854: 1487-93. PMID 26116984 DOI: 10.1016/J.Bbapap.2015.06.011  0.836
2015 Chen C, Cao R, Shrestha R, Ward C, Katz BB, Fischer CJ, Tomich JM, Li P. Trapping of intermediates with substrate analog HBOCoA in the polymerizations catalyzed by class III polyhydroxybutyrate (PHB) synthase from Allochromatium vinosum. Acs Chemical Biology. 10: 1330-9. PMID 25686368 DOI: 10.1021/Cb5009958  0.346
2014 Briggs K, Fischer CJ. All motors have to decide is what to do with the DNA that is given them. Biomolecular Concepts. 5: 383-95. PMID 25367619 DOI: 10.1515/Bmc-2014-0017  0.777
2014 Al-Ani G, Briggs K, Malik SS, Conner M, Azuma Y, Fischer CJ. Quantitative determination of binding of ISWI to nucleosomes and DNA shows allosteric regulation of DNA binding by nucleotides. Biochemistry. 53: 4334-45. PMID 24898734 DOI: 10.1021/Bi500224T  0.847
2014 Al-Ani G, Malik SS, Eastlund A, Briggs K, Fischer CJ. ISWI remodels nucleosomes through a random walk. Biochemistry. 53: 4346-57. PMID 24898619 DOI: 10.1021/Bi500226B  0.806
2013 Eastlund A, Malik SS, Fischer CJ. Kinetic mechanism of DNA translocation by the RSC molecular motor. Archives of Biochemistry and Biophysics. 532: 73-83. PMID 23399434 DOI: 10.1016/J.Abb.2013.01.011  0.854
2012 Fischer CJ, Tomko EJ, Wu CG, Lohman TM. Fluorescence methods to study DNA translocation and unwinding kinetics by nucleic acid motors. Methods in Molecular Biology (Clifton, N.J.). 875: 85-104. PMID 22573437 DOI: 10.1007/978-1-61779-806-1_5  0.832
2012 Tomko EJ, Fischer CJ, Lohman TM. Single-stranded DNA translocation of E. coli UvrD monomer is tightly coupled to ATP hydrolysis. Journal of Molecular Biology. 418: 32-46. PMID 22342931 DOI: 10.1016/J.Jmb.2012.02.013  0.843
2011 Malik SS, Rich E, Viswanathan R, Cairns BR, Fischer CJ. Allosteric interactions of DNA and nucleotides with S. cerevisiae RSC. Biochemistry. 50: 7881-90. PMID 21834590 DOI: 10.1021/Bi200837B  0.645
2010 Khaki AR, Field C, Malik S, Niedziela-Majka A, Leavitt SA, Wang R, Hung M, Sakowicz R, Brendza KM, Fischer CJ. The macroscopic rate of nucleic acid translocation by hepatitis C virus helicase NS3h is dependent on both sugar and base moieties. Journal of Molecular Biology. 400: 354-78. PMID 20451531 DOI: 10.1016/J.Jmb.2010.04.065  0.823
2010 Tomko EJ, Fischer CJ, Lohman TM. Ensemble methods for monitoring enzyme translocation along single stranded nucleic acids. Methods (San Diego, Calif.). 51: 269-76. PMID 20371288 DOI: 10.1016/J.Ymeth.2010.03.010  0.788
2010 Fischer CJ, Wooten L, Tomko EJ, Lohman TM. Kinetics of motor protein translocation on single-stranded DNA. Methods in Molecular Biology (Clifton, N.J.). 587: 45-56. PMID 20225141 DOI: 10.1007/978-1-60327-355-8_4  0.84
2010 Matlock DL, Yeruva L, Byrd AK, Mackintosh SG, Langston C, Brown C, Cameron CE, Fischer CJ, Raney KD. Investigation of translocation, DNA unwinding, and protein displacement by NS3h, the helicase domain from the hepatitis C virus helicase. Biochemistry. 49: 2097-109. PMID 20108974 DOI: 10.1021/Bi901977K  0.659
2010 Eastlund A, Malik S, Fischer C. Dna Binding and Translocation by S. Cerevisiae RSC Biophysical Journal. 98: 269a-270a. DOI: 10.1016/J.Bpj.2009.12.1469  0.854
2010 Fischer CJ, Khaki AR, Field C, Malik S, Wang R, Niedziela-Majka A, Leavitt S, Hung M, Sakowicz R, Brendza KM. Nucleic Acid Translocation By Hepatitis C Virus Helicase NS3h Is Dependent on Sugar and Base Moieties Biophysical Journal. 98: 12a. DOI: 10.1016/J.Bpj.2009.12.070  0.804
2009 Fischer CJ, Yamada K, Fitzgerald DJ. Kinetic mechanism for single-stranded DNA binding and translocation by Saccharomyces cerevisiae Isw2. Biochemistry. 48: 2960-8. PMID 19203228 DOI: 10.1021/Bi8021153  0.669
2009 Fischer CJ. Kinetic Mechanism for Single stranded DNA binding and Translocation by S. cerevisiae Isw2 Biophysical Journal. 96: 415a. DOI: 10.1016/J.Bpj.2008.12.2118  0.675
2007 Fischer CJ, Saha A, Cairns BR. Kinetic model for the ATP-dependent translocation of Saccharomyces cerevisiae RSC along double-stranded DNA. Biochemistry. 46: 12416-26. PMID 17918861 DOI: 10.1021/Bi700930N  0.682
2007 Tomko EJ, Fischer CJ, Niedziela-Majka A, Lohman TM. A nonuniform stepping mechanism for E. coli UvrD monomer translocation along single-stranded DNA. Molecular Cell. 26: 335-47. PMID 17499041 DOI: 10.1016/J.Molcel.2007.03.024  0.847
2005 Brendza KM, Cheng W, Fischer CJ, Chesnik MA, Niedziela-Majka A, Lohman TM. Autoinhibition of Escherichia coli Rep monomer helicase activity by its 2B subdomain. Proceedings of the National Academy of Sciences of the United States of America. 102: 10076-81. PMID 16009938 DOI: 10.1073/Pnas.0502886102  0.834
2004 Fischer CJ, Maluf NK, Lohman TM. Mechanism of ATP-dependent translocation of E.coli UvrD monomers along single-stranded DNA. Journal of Molecular Biology. 344: 1287-309. PMID 15561144 DOI: 10.1016/J.Jmb.2004.10.005  0.859
2004 Fischer CJ, Lohman TM. ATP-dependent translocation of proteins along single-stranded DNA: models and methods of analysis of pre-steady state kinetics. Journal of Molecular Biology. 344: 1265-86. PMID 15561143 DOI: 10.1016/J.Jmb.2004.10.004  0.748
2003 Lucius AL, Maluf NK, Fischer CJ, Lohman TM. General methods for analysis of sequential "n-step" kinetic mechanisms: application to single turnover kinetics of helicase-catalyzed DNA unwinding. Biophysical Journal. 85: 2224-39. PMID 14507688 DOI: 10.1016/S0006-3495(03)74648-7  0.829
2003 Maluf NK, Fischer CJ, Lohman TM. A Dimer of Escherichia coli UvrD is the active form of the helicase in vitro. Journal of Molecular Biology. 325: 913-35. PMID 12527299 DOI: 10.1016/S0022-2836(02)01277-9  0.856
2003 Lohman TM, Hsieh J, Maluf NK, Cheng W, Lucius AL, Fischer CJ, Brendza KM, Korolev S, Waksman G. DNA helicases, motors that move along nucleic acids: Lessons from the SF1 helicase superfamily Enzymes. 23: 303-369,III-VII. DOI: 10.1016/S1874-6047(04)80008-8  0.828
2002 Fischer CJ, Gafni A, Steel DG, Schauerte JA. The triplet-state lifetime of indole in aqueous and viscous environments: significance to the interpretation of room temperature phosphorescence in proteins. Journal of the American Chemical Society. 124: 10359-66. PMID 12197738 DOI: 10.1021/Ja016609X  0.576
2001 Fischer CJ, Schauerte JA, Wisser KC, Steel DG, Gafni A. Differences in the pathways for unfolding and hydrogen exchange among mutants of Escherichia coli alkaline phosphatase. Biochimica Et Biophysica Acta. 1545: 96-103. PMID 11342035 DOI: 10.1016/S0167-4838(00)00266-1  0.604
2000 Fischer CJ, Schauerte JA, Wisser KC, Gafni A, Steel DG. Hydrogen exchange at the core of Escherichia coli alkaline phosphatase studied by room-temperature tryptophan phosphorescence. Biochemistry. 39: 1455-61. PMID 10684627 DOI: 10.1021/Bi991560H  0.605
1998 Gershenson A, Fischer CJ, Schauerte JA, Steel DG, Gafni A. Rapid events in protein folding studied by laser-induced pH and temperature jumps Proceedings of Spie - the International Society For Optical Engineering. 3256: 252-262. DOI: 10.1117/12.307067  0.568
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