Nicholas W. Keiser, Ph.D. - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Ocular Gene Therapy

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Rosen BH, Evans TIA, Moll SR, Gray JS, Liang B, Sun X, Zhang Y, Jensen-Cody CW, Swatek AM, Zhou W, He N, Rotti PG, Tyler SR, Keiser NW, Anderson PJ, et al. Infection is Not Required for Mucoinflammatory Lung Disease in CFTR-knockout Ferrets. American Journal of Respiratory and Critical Care Medicine. PMID 29327941 DOI: 10.1164/Rccm.201708-1616Oc  0.338
2015 Evans TI, Joo NS, Keiser NW, Yan Z, Tyler SR, Xie W, Zhang Y, Hsiao JJ, Cho HJ, Wright ME, Wine JJ, Engelhardt JF. Glandular Proteome Identifies Antiprotease Cystatin C as a Critical Modulator of Airway Hydration and Clearance. American Journal of Respiratory Cell and Molecular Biology. PMID 26334941 DOI: 10.1165/Rcmb.2015-0090Oc  0.338
2015 Keiser NW, Birket SE, Evans IA, Tyler SR, Crooke AK, Sun X, Zhou W, Nellis JR, Stroebele EK, Chu KK, Tearney GJ, Stevens MJ, Harris JK, Rowe SM, Engelhardt JF. Defective innate immunity and hyperinflammation in newborn cystic fibrosis transmembrane conductance regulator-knockout ferret lungs. American Journal of Respiratory Cell and Molecular Biology. 52: 683-94. PMID 25317669 DOI: 10.1165/Rcmb.2014-0250Oc  0.365
2014 Sun X, Olivier AK, Yi Y, Pope CE, Hayden HS, Liang B, Sui H, Zhou W, Hager KR, Zhang Y, Liu X, Yan Z, Fisher JT, Keiser NW, Song Y, et al. Gastrointestinal pathology in juvenile and adult CFTR-knockout ferrets. The American Journal of Pathology. 184: 1309-22. PMID 24637292 DOI: 10.1016/J.Ajpath.2014.01.035  0.36
2014 Sun X, Olivier AK, Liang B, Yi Y, Sui H, Evans TI, Zhang Y, Zhou W, Tyler SR, Fisher JT, Keiser NW, Liu X, Yan Z, Song Y, Goeken JA, et al. Lung phenotype of juvenile and adult cystic fibrosis transmembrane conductance regulator-knockout ferrets. American Journal of Respiratory Cell and Molecular Biology. 50: 502-12. PMID 24074402 DOI: 10.1165/Rcmb.2013-0261Oc  0.343
2013 Yan Z, Keiser NW, Song Y, Deng X, Cheng F, Qiu J, Engelhardt JF. A novel chimeric adenoassociated virus 2/human bocavirus 1 parvovirus vector efficiently transduces human airway epithelia. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 2181-94. PMID 23896725 DOI: 10.1038/Mt.2013.92  0.385
2013 Keiser NW, Engelhardt JF. Gene delivery to the airway. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 13.9. PMID 23853081 DOI: 10.1002/0471142905.Hg1309S78  0.367
2013 Fisher JT, Tyler SR, Zhang Y, Lee BJ, Liu X, Sun X, Sui H, Liang B, Luo M, Xie W, Yi Y, Zhou W, Song Y, Keiser N, Wang K, et al. Bioelectric characterization of epithelia from neonatal CFTR knockout ferrets. American Journal of Respiratory Cell and Molecular Biology. 49: 837-44. PMID 23782101 DOI: 10.1165/Rcmb.2012-0433Oc  0.404
2013 Yan Z, Lei-Butters DC, Keiser NW, Engelhardt JF. Distinct transduction difference between adeno-associated virus type 1 and type 6 vectors in human polarized airway epithelia. Gene Therapy. 20: 328-37. PMID 22695783 DOI: 10.1038/Gt.2012.46  0.354
2012 Kaminsky PM, Keiser NW, Yan Z, Lei-Butters DC, Engelhardt JF. Directing integrin-linked endocytosis of recombinant AAV enhances productive FAK-dependent transduction. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 972-83. PMID 22233580 DOI: 10.1038/Mt.2011.295  0.362
2011 Keiser NW, Engelhardt JF. New animal models of cystic fibrosis: what are they teaching us? Current Opinion in Pulmonary Medicine. 17: 478-83. PMID 21857224 DOI: 10.1097/Mcp.0B013E32834B14C9  0.356
2011 Keiser NW, Yan Z, Zhang Y, Lei-Butters DC, Engelhardt JF. Unique characteristics of AAV1, 2, and 5 viral entry, intracellular trafficking, and nuclear import define transduction efficiency in HeLa cells. Human Gene Therapy. 22: 1433-44. PMID 21574868 DOI: 10.1089/Hum.2011.044  0.347
2006 Keiser NW, Maminishkis A, Bennicelli JL, Miller SS, Bennett J. 886. AAV-Mediated Somatic Gene Transfer as an Approach To Delineate Pathogenic Mechanisms in an Autosomal Dominant Blindness Disorder Resembling Age-Related Macular Degeneration (AMD) Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.975  0.509
2005 Keiser NW, Tang W, Wei Z, Bennett J. Spatial and temporal expression patterns of the choroideremia gene in the mouse retina. Molecular Vision. 11: 1052-60. PMID 16357828  0.469
2005 Keiser NW, Chung DC, Tang W, Wei Z, Maguire A, Bennett J, Bennicelli JL. 135. AAV-Mediated Gene Delivery To Evaluate the Biology of an Inherited Macular Degeneration Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.140  0.501
2001 Mautino MR, Keiser N, Morgan RA. Inhibition of Human Immunodeficiency Virus Type 1 (HIV-1) Replication by HIV-1-Based Lentivirus Vectors Expressing Transdominant Rev Journal of Virology. 75: 3590-3599. PMID 11264348 DOI: 10.1128/Jvi.75.8.3590-3599.2001  0.317
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