Fuqiang Ban, Ph.D. - Publications

Affiliations: 
Dalhousie University, Halifax, Nova Scotia, Canada 

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Li SW, Liu Y, Sampson PB, Patel NK, Forrest BT, Edwards L, Laufer R, Feher M, Ban F, Awrey DE, Hodgson R, Beletskaya I, Mao G, Mason JM, Wei X, et al. Design and optimization of (3-aryl-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-ones as potent PLK4 inhibitors with oral antitumor efficacy. Bioorganic & Medicinal Chemistry Letters. PMID 27592744 DOI: 10.1016/j.bmcl.2016.08.063  0.68
2015 Liu Y, Lang Y, Patel NK, Ng G, Laufer R, Li SW, Edwards L, Forrest B, Sampson PB, Feher M, Ban F, Awrey DE, Beletskaya I, Mao G, Hodgson R, et al. The Discovery of Orally Bioavailable Tyrosine Threonine Kinase (TTK) Inhibitors: 3-(4-(heterocyclyl)phenyl)-1H-indazole-5-carboxamides as Anticancer Agents. Journal of Medicinal Chemistry. 58: 3366-92. PMID 25763473 DOI: 10.1021/jm501740a  0.68
2015 Sampson PB, Liu Y, Forrest B, Cumming G, Li SW, Patel NK, Edwards L, Laufer R, Feher M, Ban F, Awrey DE, Mao G, Plotnikova O, Hodgson R, Beletskaya I, et al. The discovery of Polo-like kinase 4 inhibitors: identification of (1R,2S).2-(3-((E).4-(((cis).2,6-dimethylmorpholino)methyl)styryl). 1H.indazol-6-yl)-5'-methoxyspiro[cyclopropane-1,3'-indolin]-2'-one (CFI-400945) as a potent, orally active antitumor agent. Journal of Medicinal Chemistry. 58: 147-69. PMID 25723005 DOI: 10.1021/jm5005336  0.68
2014 Munuganti RS, Hassona MD, Leblanc E, Frewin K, Singh K, Ma D, Ban F, Hsing M, Adomat H, Lallous N, Andre C, Jonadass JP, Zoubeidi A, Young RN, Guns ET, et al. Identification of a potent antiandrogen that targets the BF3 site of the androgen receptor and inhibits enzalutamide-resistant prostate cancer. Chemistry & Biology. 21: 1476-85. PMID 25459660 DOI: 10.1016/j.chembiol.2014.09.012  0.68
2014 Dalal K, Roshan-Moniri M, Sharma A, Li H, Ban F, Hassona MD, Hessein M, Hsing M, Singh K, LeBlanc E, Dehm S, Tomlinson Guns ES, Cherkasov A, Rennie PS. Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer. The Journal of Biological Chemistry. 289: 26417-29. PMID 25086042 DOI: 10.1074/jbc.M114.553818  0.68
2014 Li H, Ban F, Dalal K, Leblanc E, Frewin K, Ma D, Adomat H, Rennie PS, Cherkasov A. Discovery of small-molecule inhibitors selectively targeting the DNA-binding domain of the human androgen receptor Journal of Medicinal Chemistry. 57: 6458-6467. PMID 25062331 DOI: 10.1021/jm500802j  0.68
2014 Laufer R, Ng G, Liu Y, Patel NK, Edwards LG, Lang Y, Li SW, Feher M, Awrey DE, Leung G, Beletskaya I, Plotnikova O, Mason JM, Hodgson R, Wei X, ... ... Ban F, et al. Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides. Bioorganic & Medicinal Chemistry. 22: 4968-97. PMID 25043312 DOI: 10.1016/j.bmc.2014.06.027  0.68
2014 Ban F, Leblanc E, Li H, Munuganti RSN, Frewin K, Rennie PS, Cherkasov A. Discovery of 1 H-indole-2-carboxamides as novel inhibitors of the androgen receptor binding function 3 (BF3) Journal of Medicinal Chemistry. 57: 6867-6872. PMID 25025737 DOI: 10.1021/jm500684r  0.68
2013 Laufer R, Forrest B, Li SW, Liu Y, Sampson P, Edwards L, Lang Y, Awrey DE, Mao G, Plotnikova O, Leung G, Hodgson R, Beletskaya I, Mason JM, Luo X, ... ... Ban F, et al. The discovery of PLK4 inhibitors: (E)-3-((1H-Indazol-6-yl)methylene)indolin-2-ones as novel antiproliferative agents. Journal of Medicinal Chemistry. 56: 6069-87. PMID 23829549 DOI: 10.1021/jm400380m  0.68
2013 Yu DH, Ban FQ, Zhao M, Lu Q, Lovell JF, Bai F, Wang C, Guan YY, Luan X, Liu YR, Fang C, Chen HZ. The use of nanoparticulate delivery systems in metronomic chemotherapy. Biomaterials. 34: 3925-37. PMID 23465835 DOI: 10.1016/j.biomaterials.2013.02.017  0.68
2013 Munuganti RSN, Leblanc E, Axerio-Cilies P, Labriere C, Frewin K, Singh K, Hassona MDH, Lack NA, Li H, Ban F, Tomlinson Guns E, Young R, Rennie PS, Cherkasov A. Targeting the binding function 3 (BF3) site of the androgen receptor through virtual screening. 2. Development of 2-((2-phenoxyethyl) thio)-1H-benzimidazole derivatives Journal of Medicinal Chemistry. 56: 1136-1148. PMID 23301637 DOI: 10.1021/jm3015712  0.68
2009 Danumah C, Beingessner RL, Haque A, Ban F, Richards JP, Kovalenko A, Fenniri H. Synthesis, properties, and mechanistic insight into the self-assembly of a lamellar fibrous superstructure from a synthetically simple discotic molecule. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 11857-61. PMID 19555114 DOI: 10.1021/la901511v  0.68
2008 Cherkasov A, Ban F, Santos-Filho O, Thorsteinson N, Fallahi M, Hammond GL. An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin. Journal of Medicinal Chemistry. 51: 2047-56. PMID 18330978 DOI: 10.1021/jm7011485  0.68
2007 Nandan D, Lopez M, Ban F, Huang M, Li Y, Reiner NE, Cherkasov A. Indel-based targeting of essential proteins in human pathogens that have close host orthologue(s): discovery of selective inhibitors for Leishmania donovani elongation factor-1alpha. Proteins. 67: 53-64. PMID 17243179 DOI: 10.1002/prot.21278  0.68
2006 Liu N, Ban F, Boyd RJ. Modeling competitive reaction mechanisms of peroxynitrite oxidation of guanine. The Journal of Physical Chemistry. A. 110: 9908-14. PMID 16898693 DOI: 10.1021/jp061297b  0.68
2005 Pearson JK, Ban F, Boyd RJ. An evaluation of various computational methods for the treatment of organoselenium compounds. The Journal of Physical Chemistry. A. 109: 10373-9. PMID 16833333 DOI: 10.1021/jp054185d  0.68
2004 Ban F, Kusalik P, Weaver DF. Density functional theory investigations on the chemical basis of the selectivity filter in the K+ channel protein. Journal of the American Chemical Society. 126: 4711-6. PMID 15070390 DOI: 10.1021/ja0367290  0.68
2003 Wu Z, Ban F, Boyd RJ. Modeling the reaction mechanisms of the amide hydrolysis in an N-(o-carboxybenzoyl)-L-amino acid. Journal of the American Chemical Society. 125: 6994-7000. PMID 12783553 DOI: 10.1021/ja021329i  0.68
2003 Wu Z, Ban F, Boyd RJ. Modeling the reaction mechanisms of the imide formation in an N-(o-carboxybenzoyl)-L-amino acid. Journal of the American Chemical Society. 125: 3642-8. PMID 12643727 DOI: 10.1021/ja020700z  0.68
2002 Ban F, Lundqvist MJ, Boyd RJ, Eriksson LA. Theoretical studies of the cross-linking mechanisms between cytosine and tyrosine. Journal of the American Chemical Society. 124: 2753-61. PMID 11890827 DOI: 10.1021/ja011528m  0.68
2001 Ban F, Gauld JW, Boyd RJ. Modeling the action of an antitumor drug: a density functional theory study of the mechanism of tirapazamine. Journal of the American Chemical Society. 123: 7320-5. PMID 11472160 DOI: 10.1021/ja010772a  0.68
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