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Manjinder S. Lall, Ph.D. - Publications

Affiliations: 
University of Alberta, Edmonton, Alberta, Canada 
Area:
Bioorganic chemistry
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12/38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Lall MS, Ramtohul YK, James MNG, Vederas JC. ChemInform Abstract: Serine and Threonine β-Lactones: A New Class of Hepatitis A Virus 3C Cysteine Proteinase Inhibitors. Cheminform. 33: no-no. DOI: 10.1002/chin.200236107  0.554
2005 Yin J, Bergmann EM, Cherney MM, Lall MS, Jain RP, Vederas JC, James MN. Dual modes of modification of hepatitis A virus 3C protease by a serine-derived beta-lactone: selective crystallization and formation of a functional catalytic triad in the active site. Journal of Molecular Biology. 354: 854-71. PMID 16288920 DOI: 10.1016/J.Jmb.2005.09.074  0.7
2005 Yin J, Bergmann EM, Cherney MM, Lall MS, Jain RP, Vederas JC, James MN. Dual modes of modification of hepatitis A virus 3C protease by a serine-derived beta-lactone: selective crystallization and formation of a functional catalytic triad in the active site. Journal of Molecular Biology. 354: 854-71. PMID 16288920 DOI: 10.1016/J.Jmb.2005.09.074  0.7
2005 Yin J, Bergmann EM, Cherney MM, Lall MS, Jain RP, Vederas JC, James MNG. Crystal structure of HAV 3C protease complexed with a β-lactone inhibitor: a new crystal form of HAV 3C and its application for studying enzyme-inhibitor interaction Acta Crystallographica Section a Foundations of Crystallography. 61: c206-c206. DOI: 10.1107/S0108767305091233  0.537
2004 Lall MS, Jain RP, Vederas JC. Inhibitors of 3C cysteine proteinases from Picornaviridae. Current Topics in Medicinal Chemistry. 4: 1239-53. PMID 15320724 DOI: 10.2174/1568026043387836  0.653
2004 Lall MS, Jain RP, Vederas JC. Inhibitors of 3C cysteine proteinases from Picornaviridae. Current Topics in Medicinal Chemistry. 4: 1239-53. PMID 15320724 DOI: 10.2174/1568026043387836  0.653
2002 Lall MS, Ramtohul YK, James MN, Vederas JC. Serine and threonine beta-lactones: a new class of hepatitis A virus 3C cysteine proteinase inhibitors. The Journal of Organic Chemistry. 67: 1536-47. PMID 11871884 DOI: 10.1021/Jo0109016  0.693
2002 Lall MS, Ramtohul YK, James MN, Vederas JC. Serine and threonine beta-lactones: a new class of hepatitis A virus 3C cysteine proteinase inhibitors. The Journal of Organic Chemistry. 67: 1536-47. PMID 11871884 DOI: 10.1021/Jo0109016  0.693
1999 Lall MS, Karvellas C, Vederas JC. β-Lactones as a new class of cysteine proteinase inhibitors: inhibition of hepatitis A virus 3C proteinase by N-Cbz-serine β-Lactone Organic Letters. 1: 803-806. PMID 10823207 DOI: 10.1021/Ol990148R  0.763
1999 Lall MS, Karvellas C, Vederas JC. β-Lactones as a new class of cysteine proteinase inhibitors: inhibition of hepatitis A virus 3C proteinase by N-Cbz-serine β-Lactone Organic Letters. 1: 803-806. PMID 10823207  0.379
1997 Morris TS, Frormann S, Shechosky S, Lowe C, Lall MS, Gauss-Müller V, Purcell RH, Emerson SU, Vederas JC, Malcolm BA. In vitro and ex vivo inhibition of hepatitis A virus 3C proteinase by a peptidyl monofluoromethyl ketone. Bioorganic & Medicinal Chemistry. 5: 797-807. PMID 9208091 DOI: 10.1016/S0968-0896(97)88649-X  0.678
1997 Morris TS, Frormann S, Shechosky S, Lowe C, Lall MS, Gauss-Müller V, Purcell RH, Emerson SU, Vederas JC, Malcolm BA. In vitro and ex vivo inhibition of hepatitis A virus 3C proteinase by a peptidyl monofluoromethyl ketone. Bioorganic & Medicinal Chemistry. 5: 797-807. PMID 9208091 DOI: 10.1016/S0968-0896(97)88649-X  0.678
Low-probability matches (unlikely to be authored by this person)
2022 Ryder TF, Bergman A, King-Ahmad A, Amin NB, Lall MS, Ballard TE, Kalgutkar AS. Pharmacokinetics, mass balance, metabolism, and excretion of the liver-targeted acetyl-CoA carboxylase inhibitor PF-05221304 (clesacostat) in humans. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-14. PMID 35382680 DOI: 10.1080/00498254.2022.2062487  0.271
2022 Ren X, Couture BM, Liu N, Lall MS, Kohrt JT, Fasan R. Enantioselective Single and Dual α-C-H Bond Functionalization of Cyclic Amines via Enzymatic Carbene Transfer. Journal of the American Chemical Society. PMID 36542059 DOI: 10.1021/jacs.2c10775  0.257
2010 Miller JR, Thanabal V, Melnick MM, Lall M, Donovan C, Sarver RW, Lee DY, Ohren J, Emerson D. The use of biochemical and biophysical tools for triage of high-throughput screening hits - aa case study with escherichia coli phosphopantetheine adenylyltransferase Chemical Biology and Drug Design. 75: 444-454. PMID 20486930 DOI: 10.1111/j.1747-0285.2010.00957.x  0.227
2010 Qi XB, Rice GT, Lall MS, Plummer MS, White MC. Diversification of a β-Lactam Pharmacophore via Allylic C-H Amination: Accelerating Effect of Lewis Acid Co-Catalyst. Tetrahedron. 66: 4816-4826. PMID 21379377 DOI: 10.1016/J.Tet.2010.04.064  0.216
2010 Qi X, Rice GT, Lall MS, Plummer MS, White MC. Diversification of a β-lactam pharmacophore via allylic C-H amination: Accelerating effect of Lewis acid co-catalyst Tetrahedron. 66: 4816-4826. DOI: 10.1016/j.tet.2010.04.064  0.164
2010 Qi X, Rice GT, Lall MS, Plummer MS, White MC. Diversification of a β-lactam pharmacophore via allylic C-H amination: Accelerating effect of Lewis acid co-catalyst Tetrahedron. 66: 4816-4826. DOI: 10.1016/j.tet.2010.04.064  0.164
2012 Lall MS, Hoge G, Tran TP, Kissel W, Murphy ST, Taylor C, Hutchings K, Samas B, Ellsworth EL, Curran T, Showalter HD. Stereoselective synthesis of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile. The Journal of Organic Chemistry. 77: 4732-9. PMID 22524537 DOI: 10.1021/jo3004716  0.163
2012 Lall MS, Hoge G, Tran TP, Kissel W, Murphy ST, Taylor C, Hutchings K, Samas B, Ellsworth EL, Curran T, Showalter HD. Stereoselective synthesis of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile. The Journal of Organic Chemistry. 77: 4732-9. PMID 22524537 DOI: 10.1021/jo3004716  0.163
2020 Lall MS, Bassyouni A, Bradow J, Brown M, Bundesmann MW, Chen J, Ciszewski G, Hagen A, Hyek D, Jenkinson S, Liu B, Obach RS, Pan S, Reilly U, Sach NW, et al. Late Stage Lead Diversification (LSLD) Coupled with Quantitative NMR Spectroscopy to Identify New SAR Vectors at Nanomole Scale Synthesis: Application to Loratadine a Human Histamine H Receptor Inverse Agonist. Journal of Medicinal Chemistry. PMID 32462865 DOI: 10.1021/acs.jmedchem.0c00483  0.161
2010 White M, Qi X, Rice G, Lall M, Plummer M. Accelerating Effect of Lewis Acid Co-Catalyst on C-H Amination Synfacts. 2010: 1050-1050. DOI: 10.1055/s-0030-1257893  0.144
2007 Boyer FE, Vara Prasad JVN, Choy AL, Chupak L, Dermyer MR, Ding Q, Huband MD, Jiao W, Kaneko T, Khlebnikov V, Kim JY, Lall MS, Maiti SN, Romero K, Wu X. Synthesis and SAR of novel conformationally-restricted oxazolidinones possessing Gram-positive and fastidious Gram-negative antibacterial activity. Part 1: Substituted pyrazoles Bioorganic and Medicinal Chemistry Letters. 17: 4694-4698. PMID 17590334 DOI: 10.1016/j.bmcl.2007.05.056  0.138
2007 Boyer FE, Vara Prasad JVN, Choy AL, Chupak L, Dermyer MR, Ding Q, Huband MD, Jiao W, Kaneko T, Khlebnikov V, Kim JY, Lall MS, Maiti SN, Romero K, Wu X. Synthesis and SAR of novel conformationally-restricted oxazolidinones possessing Gram-positive and fastidious Gram-negative antibacterial activity. Part 1: Substituted pyrazoles Bioorganic and Medicinal Chemistry Letters. 17: 4694-4698. PMID 17590334 DOI: 10.1016/j.bmcl.2007.05.056  0.138
2011 Flanagan ME, Brickner SJ, Lall M, Casavant J, Deschenes L, Finegan SM, George DM, Granskog K, Hardink JR, Huband MD, Hoang T, Lamb L, Marra A, Mitton-Fry M, Mueller JP, et al. Preparation, gram-negative antibacterial activity, and hydrolytic stability of novel siderophore-conjugated monocarbam diols. Acs Medicinal Chemistry Letters. 2: 385-90. PMID 24900319 DOI: 10.1021/Ml200012F  0.136
2013 Brown MF, Mitton-Fry MJ, Arcari JT, Barham R, Casavant J, Gerstenberger BS, Han S, Hardink JR, Harris TM, Hoang T, Huband MD, Lall MS, Lemmon MM, Li C, Lin J, et al. Pyridone-conjugated monobactam antibiotics with gram-negative activity. Journal of Medicinal Chemistry. 56: 5541-52. PMID 23755848 DOI: 10.1021/Jm400560Z  0.133
2013 Brown MF, Mitton-Fry MJ, Arcari JT, Barham R, Casavant J, Gerstenberger BS, Han S, Hardink JR, Harris TM, Hoang T, Huband MD, Lall MS, Lemmon MM, Li C, Lin J, et al. Pyridone-conjugated monobactam antibiotics with gram-negative activity. Journal of Medicinal Chemistry. 56: 5541-52. PMID 23755848 DOI: 10.1021/Jm400560Z  0.133
2012 Mitton-Fry MJ, Arcari JT, Brown MF, Casavant JM, Finegan SM, Flanagan ME, Gao H, George DM, Gerstenberger BS, Han S, Hardink JR, Harris TM, Hoang T, Huband MD, Irvine R, ... Lall MS, et al. Novel monobactams utilizing a siderophore uptake mechanism for the treatment of gram-negative infections. Bioorganic & Medicinal Chemistry Letters. 22: 5989-94. PMID 22892121 DOI: 10.1016/J.Bmcl.2012.07.005  0.116
2012 Mitton-Fry MJ, Arcari JT, Brown MF, Casavant JM, Finegan SM, Flanagan ME, Gao H, George DM, Gerstenberger BS, Han S, Hardink JR, Harris TM, Hoang T, Huband MD, Irvine R, ... Lall MS, et al. Novel monobactams utilizing a siderophore uptake mechanism for the treatment of gram-negative infections. Bioorganic & Medicinal Chemistry Letters. 22: 5989-94. PMID 22892121 DOI: 10.1016/J.Bmcl.2012.07.005  0.116
2009 Starr JT, Sciotti RJ, Hanna DL, Huband MD, Mullins LM, Cai H, Gage JW, Lockard M, Rauckhorst MR, Owen RM, Lall MS, Tomilo M, Chen H, McCurdy SP, Barbachyn MR. 5-(2-Pyrimidinyl)-imidazo[1,2-a]pyridines are antibacterial agents targeting the ATPase domains of DNA gyrase and topoisomerase IV. Bioorganic & Medicinal Chemistry Letters. 19: 5302-6. PMID 19683922 DOI: 10.1016/J.Bmcl.2009.07.141  0.105
2015 Mitton-Fry MJ, Arcari JT, Brown MF, Casavant JM, Finegan SM, Flanagan ME, Gao H, George DM, Gerstenberger BS, Han S, Hardink JR, Harris TM, Hoang T, Huband MD, Irvine R, ... Lall MS, et al. Corrigendum to "Novel monobactams utilizing a siderophore uptake mechanism for the treatment of Gram-negative infections" [Bioorg. Med. Chem. Lett. 22/18 (2012) 5989-5994] Bioorganic and Medicinal Chemistry Letters. 25: 4029. DOI: 10.1016/J.Bmcl.2015.07.024  0.088
2015 Mitton-Fry MJ, Arcari JT, Brown MF, Casavant JM, Finegan SM, Flanagan ME, Gao H, George DM, Gerstenberger BS, Han S, Hardink JR, Harris TM, Hoang T, Huband MD, Irvine R, ... Lall MS, et al. Corrigendum to "Novel monobactams utilizing a siderophore uptake mechanism for the treatment of Gram-negative infections" [Bioorg. Med. Chem. Lett. 22/18 (2012) 5989-5994] Bioorganic and Medicinal Chemistry Letters. 25: 4029. DOI: 10.1016/J.Bmcl.2015.07.024  0.088
2019 Tao Y, Lall MS, Boyles DC, Lilley SC, Pattavina SD, Rafka RJ, Sitter BJ, Stewart AM, Szeliga J, Weisenburger GA. Enabled Process To Synthesize Monobactam 1 for Early Development Organic Process Research & Development. 23: 2499-2509. DOI: 10.1021/acs.oprd.9b00374  0.067
2003 Fujita M, Mah HM, Sgarbi PWM, Lall MS, Ly TW, Browne LM. Separation of Acids, Bases, and Neutral Compounds Journal of Chemical Education. 80: 107. DOI: 10.1021/ed080p107  0.066
2016 Farley KA, Reilly U, Anderson DP, Boscoe BP, Bundesmann MW, Foley DA, Lall MS, Li C, Reese MR, Yan J. Utilizing on- and off-line monitoring tools to follow a kinetic resolution step during flow synthesis. Magnetic Resonance in Chemistry : Mrc. PMID 27469271 DOI: 10.1002/mrc.4494  0.057
2009 Starr JT, Sciotti RJ, Hanna DL, Huband MD, Mullins LM, Cai H, Gage JW, Lockard M, Rauckhorst MR, Owen RM, Lall MS, Tomilo M, Chen H, McCurdy SP, Barbachyn MR. 5-(2-Pyrimidinyl)-imidazo[1,2-a]pyridines are antibacterial agents targeting the ATPase domains of DNA gyrase and topoisomerase IV Bioorganic and Medicinal Chemistry Letters. 19: 5302-5306. PMID 19683922 DOI: 10.1016/j.bmcl.2009.07.141  0.057
2021 Ratnayake AS, Flanagan ME, Foley TL, Hultgren SL, Bellenger J, Montgomery JI, Lall MS, Liu B, Ryder T, Kölmel DK, Shavnya A, Feng X, Lefker B, Byrnes LJ, Sahasrabudhe PV, et al. Toward the assembly and characterization of an encoded library hit confirmation platform: Bead-Assisted Ligand Isolation Mass Spectrometry (BALI-MS). Bioorganic & Medicinal Chemistry. 41: 116205. PMID 34000509 DOI: 10.1016/j.bmc.2021.116205  0.056
2008 Lall MS. ChemInform Abstract: Noyori Catalytic Asymmetric Hydrogenation Cheminform. 39. DOI: 10.1002/chin.200837243  0.053
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