Year |
Citation |
Score |
2024 |
Bilgin N, Tumber A, Dhingra S, Salah E, Al-Salmy A, Martín SP, Wang Y, Schofield CJ, Mecinović J. Substrate selectivity and inhibition of the human lysyl hydroxylase JMJD7. Protein Science : a Publication of the Protein Society. 33: e5162. PMID 39276004 DOI: 10.1002/pro.5162 |
0.502 |
|
2023 |
Bilgin N, Türkmen VA, Hammami N, Christensen NR, Hintzen JCJ, Mecinović J. Reading and erasing of histone crotonyllysine mimics by the AF9 YEATS domain and SIRT2 deacylase. Bioorganic & Medicinal Chemistry. 95: 117500. PMID 37839329 DOI: 10.1016/j.bmc.2023.117500 |
0.382 |
|
2023 |
Türkmen VA, Hintzen JCJ, Tumber A, Moesgaard L, Salah E, Kongsted J, Schofield CJ, Mecinović J. Substrate selectivity and inhibition of histidine JmjC hydroxylases MINA53 and NO66. Rsc Chemical Biology. 4: 235-243. PMID 36908702 DOI: 10.1039/d2cb00182a |
0.443 |
|
2022 |
Belle R, Kamps JJAG, Poater J, Kumar K, Pieters BJGE, Salah E, Claridge TDW, Paton RS, Bickelhaupt FM, Kawamura A, Schofield CJ, Mecinović J. Reading and erasing of the phosphonium analogue of trimethyllysine by epigenetic proteins. Communications Chemistry. 5: 27. PMID 36697896 DOI: 10.1038/s42004-022-00640-4 |
0.647 |
|
2022 |
Merx J, Hintzen JCJ, Proietti G, Elferink H, Wang Y, Porzberg MRB, Sondag D, Bilgin N, Park J, Mecinović J, Boltje TJ. Investigation of in vitro histone H3 glycosylation using H3 tail peptides. Scientific Reports. 12: 19251. PMID 36357422 DOI: 10.1038/s41598-022-21883-0 |
0.328 |
|
2022 |
Betlem P, Maas MN, Middelburg J, Pieters BJGE, Mecinović J. Recognition of stapled histone H3K4me3 peptides by epigenetic reader proteins. Chemical Communications (Cambridge, England). PMID 36239132 DOI: 10.1039/d2cc04294k |
0.33 |
|
2022 |
Belle R, Kamps JJAG, Poater J, Kumar K, Pieters BJGE, Salah E, Claridge TDW, Paton RS, Matthias Bickelhaupt F, Kawamura A, Schofield CJ, Mecinović J. Reading and erasing of the phosphonium analogue of trimethyllysine by epigenetic proteins. Communications Chemistry. 5. PMID 36071790 DOI: 10.1038/s42004-022-00640-4 |
0.665 |
|
2022 |
Porzberg MRB, Moesgaard L, Johansson C, Oppermann U, Kongsted J, Mecinović J. Recognition of Dimethylarginine Analogues by Tandem Tudor Domain Protein Spindlin1. Molecules (Basel, Switzerland). 27. PMID 35164245 DOI: 10.3390/molecules27030983 |
0.353 |
|
2021 |
Hintzen JCJ, Merx J, Maas MN, Langens SGHA, White PB, Boltje TJ, Mecinović J. Amide-derived lysine analogues as substrates and inhibitors of histone lysine methyltransferases and acetyltransferases. Organic & Biomolecular Chemistry. PMID 34877957 DOI: 10.1039/d1ob02191e |
0.355 |
|
2021 |
Proietti G, Wang Y, Punzo C, Mecinović J. Substrate Scope for Human Histone Lysine Acetyltransferase KAT8. International Journal of Molecular Sciences. 22. PMID 33467728 DOI: 10.3390/ijms22020846 |
0.347 |
|
2020 |
Pieters BJGE, Wuts MHM, Poater J, Kumar K, White PB, Kamps JJAG, Sherman W, Pruijn GJM, Paton RS, Beuming T, Bickelhaupt FM, Mecinović J. Mechanism of biomolecular recognition of trimethyllysine by the fluorinated aromatic cage of KDM5A PHD3 finger. Communications Chemistry. 3: 69. PMID 36703460 DOI: 10.1038/s42004-020-0313-2 |
0.35 |
|
2020 |
Al Temimi AHK, Merx J, van Noortwijk CJ, Proietti G, Buijs R, White PB, Rutjes FPJT, Boltje TJ, Mecinović J. Fine-tuning of lysine side chain modulates the activity of histone lysine methyltransferases. Scientific Reports. 10: 21574. PMID 33299050 DOI: 10.1038/s41598-020-78331-0 |
0.33 |
|
2020 |
Proietti G, Wang Y, Rainone G, Mecinović J. Effect of lysine side chain length on histone lysine acetyltransferase catalysis. Scientific Reports. 10: 13046. PMID 32747680 DOI: 10.1038/S41598-020-69510-0 |
0.449 |
|
2020 |
Jian J, Poater J, Hammink R, Tinnemans P, McKenzie CJ, Bickelhaupt FM, Mecinović J. Through-Space Polar-π Interactions in 2,6-Diarylthiophenols. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 21: 1080. PMID 32496661 DOI: 10.1002/Cphc.202000414 |
0.306 |
|
2020 |
Hintzen JCJ, Poater J, Kumar K, Al Temimi AHK, Pieters BJGE, Paton RS, Bickelhaupt FM, Mecinović J. Comparison of Molecular Recognition of Trimethyllysine and Trimethylthialysine by Epigenetic Reader Proteins. Molecules (Basel, Switzerland). 25. PMID 32326252 DOI: 10.3390/Molecules25081918 |
0.42 |
|
2020 |
Jian J, Poater J, Hammink R, Tinnemans P, McKenzie C, Bickelhaupt FM, Mecinović J. Through-Space Polar-π Interactions in 2,6-Diarylthiophenols. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. PMID 32253802 DOI: 10.1002/Cphc.202000132 |
0.308 |
|
2020 |
Temimi AHKA, Tran V, Teeuwen RS, Altunc AJ, Amatdjais-Groenen HIV, White PB, Lenstra DC, Proietti G, Wang Y, Wegert A, Blaauw RH, Qian P, Ren W, Guo H, Mecinović J. Examining sterically demanding lysine analogs for histone lysine methyltransferase catalysis. Scientific Reports. 10: 3671. PMID 32111884 DOI: 10.1038/S41598-020-60337-3 |
0.456 |
|
2020 |
Proietti G, Rainone G, Hintzen J, Mecinovic J. Exploring the Histone Acylome Through Incorporation of γ-Thialysine on Histone Tails. Bioconjugate Chemistry. PMID 32058696 DOI: 10.1021/Acs.Bioconjchem.0C00012 |
0.663 |
|
2020 |
Al Temimi AHK, White PB, Mulders MJM, van der Linden NGA, Blaauw RH, Wegert A, Rutjes FPJT, Mecinović J. Methylation of geometrically constrained lysine analogues by histone lysine methyltransferases. Chemical Communications (Cambridge, England). PMID 32048637 DOI: 10.1039/C9Cc09098C |
0.38 |
|
2019 |
Al Temimi AHK, Martin M, Meng Q, Lenstra DC, Qian P, Guo H, Weinhold E, Mecinovic J. Lysine Ethylation by Histone Lysine Methyltransferases. Chembiochem : a European Journal of Chemical Biology. PMID 31287209 DOI: 10.1002/Cbic.201900359 |
0.428 |
|
2019 |
Al Temimi AHK, Teeuwen RS, Tran V, Altunc AJ, Lenstra DC, Ren W, Qian P, Guo H, Mecinović J. Importance of the main chain of lysine for histone lysine methyltransferase catalysis. Organic & Biomolecular Chemistry. PMID 31134245 DOI: 10.1039/C9Ob01038F |
0.462 |
|
2019 |
Al Temimi AHK, van der Wekken-de Bruijne R, Proietti G, Guo H, Qian P, Mecinovic J. γ-Thialysine versus Lysine: An Insight into the Epigenetic Methylation of Histones. Bioconjugate Chemistry. PMID 31117351 DOI: 10.1021/Acs.Bioconjchem.9B00313 |
0.445 |
|
2019 |
Wang Y, Reddy YV, Al Temimi AHK, Venselaar H, Nelissen FHT, Lenstra DC, Mecinovic J. Investigating the active site of human trimethyllysine hydroxylase. The Biochemical Journal. PMID 30898847 DOI: 10.1042/Bcj20180857 |
0.388 |
|
2019 |
Pieters BJGE, Hintzen JCJ, Grobben Y, Al Temimi AHK, Kamps JJAG, Mecinović J. Installation of Trimethyllysine Analogs on Intact Histones via Cysteine Alkylation. Bioconjugate Chemistry. PMID 30794748 DOI: 10.1021/Acs.Bioconjchem.9B00065 |
0.435 |
|
2018 |
Bush JT, Leśniak RK, Yeh TL, Belle R, Kramer H, Tumber A, Chowdhury R, Flashman E, Mecinović J, Schofield CJ. Small-molecules that covalently react with a human prolyl hydroxylase - towards activity modulation and substrate capture. Chemical Communications (Cambridge, England). PMID 30452037 DOI: 10.1039/C8Cc07706A |
0.752 |
|
2018 |
Lenstra DC, Damen E, Leenders RGG, Blaauw RH, Rutjes FPJT, Wegert A, Mecinovic J. Structure-Activity Relationship Studies on (R)-PFI-2 Analogs as Inhibitors of Histone Lysine Methyltransferase SETD7. Chemmedchem. PMID 29869845 DOI: 10.1002/Cmdc.201800242 |
0.329 |
|
2018 |
Wang H, Jiang D, Axelsson E, Lorković ZJ, Montgomery S, Holec S, Pieters BJGE, Al Temimi AHK, Mecinović J, Berger F. Title: LHP1 interacts with ATRX through plant-specific domains at specific loci targeted by PRC2. Molecular Plant. PMID 29793052 DOI: 10.1016/J.Molp.2018.05.004 |
0.345 |
|
2018 |
Abboud MI, McAllister TE, Leung IKH, Chowdhury R, Jorgensen C, Domene C, Mecinović J, Lippl K, Hancock RL, Hopkinson RJ, Kawamura A, Claridge TDW, Schofield CJ. 2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2. Chemical Communications (Cambridge, England). PMID 29522057 DOI: 10.1039/C8Cc00387D |
0.684 |
|
2018 |
Lenstra DC, Al Temimi AHK, Mecinović J. Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). Bioorganic & Medicinal Chemistry Letters. PMID 29519735 DOI: 10.1016/J.Bmcl.2018.02.043 |
0.368 |
|
2018 |
Al Temimi AHK, Belle R, Kumar K, Poater J, Betlem P, Pieters BJGE, Paton RS, Bickelhaupt FM, Mecinović J. Recognition of shorter and longer trimethyllysine analogues by epigenetic reader proteins. Chemical Communications (Cambridge, England). PMID 29457186 DOI: 10.1039/C8Cc01009A |
0.407 |
|
2017 |
Belle R, Al Temimi AHK, Kumar K, Pieters BJGE, Tumber A, Dunford JE, Johansson C, Oppermann U, Brown T, Schofield CJ, Hopkinson RJ, Paton RS, Kawamura A, Mecinović J. Investigating d-lysine stereochemistry for epigenetic methylation, demethylation and recognition. Chemical Communications (Cambridge, England). 53: 13264-13267. PMID 29186216 DOI: 10.1039/C7Cc08028J |
0.654 |
|
2017 |
Temimi AHKA, Reddy YV, White PB, Guo H, Qian P, Mecinović J. Lysine Possesses the Optimal Chain Length for Histone Lysine Methyltransferase Catalysis. Scientific Reports. 7: 16148. PMID 29170487 DOI: 10.1038/S41598-017-16128-4 |
0.441 |
|
2017 |
Simó Padial J, Poater J, Nguyen DT, Tinnemans P, Bickelhaupt FM, Mecinovic J. Stabilization of 2,6-Diarylanilinum Cation by Through-Space Cation-π Interactions. The Journal of Organic Chemistry. PMID 28836782 DOI: 10.1021/Acs.Joc.7B01406 |
0.306 |
|
2016 |
Al Temimi AH, Pieters BJ, Reddy YV, White PB, Mecinović J. Substrate scope for trimethyllysine hydroxylase catalysis. Chemical Communications (Cambridge, England). PMID 27730239 DOI: 10.1039/C6Cc07845A |
0.337 |
|
2016 |
Kamps JJAG, Khan A, Choi H, Lesniak RK, Brem J, Rydzik AM, McDonough MA, Schofield CJ, Claridge TDW, Mecinović J. Frontispiece: Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis Chemistry - a European Journal. 22. DOI: 10.1002/Chem.201680462 |
0.735 |
|
2015 |
Kamps JJ, Khan A, Choi H, Lesniak RK, Brem J, Rydzik AM, McDonough MA, Schofield CJ, Claridge TD, Mecinović J. Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26660433 DOI: 10.1002/Chem.201503761 |
0.752 |
|
2015 |
Kamps JJ, Huang J, Poater J, Xu C, Pieters BJ, Dong A, Min J, Sherman W, Beuming T, Matthias Bickelhaupt F, Li H, Mecinović J. Chemical basis for the recognition of trimethyllysine by epigenetic reader proteins. Nature Communications. 6: 8911. PMID 26578293 DOI: 10.1038/Ncomms9911 |
0.399 |
|
2015 |
Pieters BJ, Meulenbroeks E, Belle R, Mecinović J. The Role of Electrostatic Interactions in Binding of Histone H3K4me2/3 to the Sgf29 Tandem Tudor Domain. Plos One. 10: e0139205. PMID 26421618 DOI: 10.1371/Journal.Pone.0139205 |
0.473 |
|
2015 |
Lenstra DC, Nguyen DT, Mecinović J. Zirconium-catalyzed direct amide bond formation between carboxylic esters and amines Tetrahedron. 71: 5547-5553. DOI: 10.1016/J.Tet.2015.06.066 |
0.301 |
|
2014 |
van Eldijk MB, Smits FC, Thies JC, Mecinović J, van Hest JC. Thermodynamic investigation of Z33-antibody interaction leads to selective purification of human antibodies. Journal of Biotechnology. 179: 32-41. PMID 24667538 DOI: 10.1016/J.Jbiotec.2014.03.023 |
0.349 |
|
2014 |
Van Eldijk MB, Pieters BJ, Mikhailov VA, Robinson CV, Van Hest JCM, Mecinović J. Catenane versus ring: Do both assemblies of CS2 hydrolase exhibit the same stability and catalytic activity? Chemical Science. 5: 2879-2884. DOI: 10.1039/C4Sc00059E |
0.304 |
|
2013 |
Pieters B, Belle R, Mecinović J. The effect of the length of histone H3K4me3 on recognition by reader proteins. Chembiochem : a European Journal of Chemical Biology. 14: 2408-12. PMID 24307373 DOI: 10.1002/Cbic.201300525 |
0.385 |
|
2011 |
Snyder PW, Mecinovic J, Moustakas DT, Thomas SW, Harder M, Mack ET, Lockett MR, Héroux A, Sherman W, Whitesides GM. Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase. Proceedings of the National Academy of Sciences of the United States of America. 108: 17889-94. PMID 22011572 DOI: 10.1073/Pnas.1114107108 |
0.669 |
|
2011 |
Mecinović J, Snyder PW, Mirica KA, Bai S, Mack ET, Kwant RL, Moustakas DT, Héroux A, Whitesides GM. Fluoroalkyl and alkyl chains have similar hydrophobicities in binding to the "hydrophobic wall" of carbonic anhydrase. Journal of the American Chemical Society. 133: 14017-26. PMID 21790183 DOI: 10.1021/Ja2045293 |
0.68 |
|
2010 |
Kelly DJ, Mecinovic J, Arnold N, Suvarna K, Schofield CJ, Gunn J, Gershlick AH. 104 Upregulation of hypoxia-inducible factor 1α by di-methyl oxalyl glycine promotes angiogenesis within ischaemic myocardium in a porcine coronary occlusion model Heart. 96: A61.2-A62. DOI: 10.1136/Hrt.2010.196071.26 |
0.384 |
|
2010 |
Kelly DJ, Mecinovic J, Arnold N, Suvarna K, Schofield CJ, Gunn J, Gershlick AH. UPREGULATION OF HYPOXIA-INDUCIBLE FACTOR BY DI-METHYL OXALYL GLYCINE (DMOG) INCREASES NEOVASCULARIZATION WITHIN ISCHAEMIC MYOCARDIUM IN A PORCINE CORONARY OCCLUSION MODEL Journal of the American College of Cardiology. 55: A216.E2047. DOI: 10.1016/S0735-1097(10)62048-7 |
0.41 |
|
2009 |
Cook KM, Hilton ST, Mecinovic J, Motherwell WB, Figg WD, Schofield CJ. Epidithiodiketopiperazines block the interaction between hypoxia-inducible factor-1alpha (HIF-1alpha) and p300 by a zinc ejection mechanism. The Journal of Biological Chemistry. 284: 26831-8. PMID 19589782 DOI: 10.1074/Jbc.M109.009498 |
0.454 |
|
2009 |
Thalhammer A, Mecinović J, Schofield CJ. Triflic anhydride-mediated synthesis of oxazoles Tetrahedron Letters. 50: 1045-1047. DOI: 10.1016/J.Tetlet.2008.12.080 |
0.411 |
|
2009 |
Hamed RB, Batchelar ET, Mecinović J, Claridge TDW, Schofield CJ. Cover Picture: Evidence that Thienamycin Biosynthesis Proceeds via C-5 Epimerization: ThnE Catalyzes the Formation of (2S,5S)-trans-Carboxymethylproline (ChemBioChem 2/2009) Chembiochem. 10: 189-189. DOI: 10.1002/Cbic.200990000 |
0.603 |
|
2008 |
Mecinović J, Chowdhury R, Liénard BM, Flashman E, Buck M, Oldham N, Schofield C. Cover Picture: ESI-MS Studies on Prolyl Hydroxylase Domain 2 Reveal a New Metal Binding Site (ChemMedChem 4/2008) Chemmedchem. 3: 509-509. DOI: 10.1002/Cmdc.200890014 |
0.586 |
|
2007 |
Coleman ML, McDonough MA, Hewitson KS, Coles C, Mecinovic J, Edelmann M, Cook KM, Cockman ME, Lancaster DE, Kessler BM, Oldham NJ, Ratcliffe PJ, Schofield CJ. Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor. The Journal of Biological Chemistry. 282: 24027-38. PMID 17573339 DOI: 10.1074/Jbc.M704102200 |
0.625 |
|
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